Repetitive Sequences, Nucleic Acid
-
Subject Areas on Research
-
50 million years of genomic stasis in endosymbiotic bacteria.
-
A 6-Mb high-resolution physical and transcription map encompassing the hereditary prostate cancer 1 (HPC1) region.
-
A T cell-specific transcriptional enhancer within the human T cell receptor delta locus.
-
A Xenopus egg factor with DNA-binding properties characteristic of terminus-specific telomeric proteins.
-
A compound nucleotide repeat in the neurofibromatosis (NF1) gene.
-
A comprehensive panel of near-full-length clones and reference sequences for non-subtype B isolates of human immunodeficiency virus type 1.
-
A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors.
-
A disease locus for hereditary haemorrhagic telangiectasia maps to chromosome 9q33-34.
-
A family of long reiterated DNA sequences, one copy of which is next to the human beta globin gene.
-
A functional prodynorphin promoter polymorphism and opioid dependence.
-
A genetic linkage map of the laboratory rat, Rattus norvegicus.
-
A molecular analysis of hyalin--a substrate for cell adhesion in the hyaline layer of the sea urchin embryo.
-
A physical map of the human genome.
-
A positive addition to a negative tail's tale.
-
A radiation hybrid map of the distal short arm of human chromosome 11, containing the Beckwith-Wiedemann and associated embryonal tumor disease loci.
-
A sea urchin genome project: sequence scan, virtual map, and additional resources.
-
A study of the repetitive structure and distribution of short motifs in human genomic sequences.
-
Absence of a correlation of androgen receptor gene CAG repeat length and prostate cancer risk in an African-American population.
-
Acquisition and processing of a conditional dicentric chromosome in Saccharomyces cerevisiae.
-
Adenosine deaminase (ADA) deficiency due to deletion of the ADA gene promoter and first exon by homologous recombination between two Alu elements.
-
Alu RNA-protein complexes formed in vitro react with a novel lupus autoantibody.
-
Alu-PCR fingerprinting of YACs.
-
An Exploration of Fern Genome Space
-
An extensive de novo deletion removing FMR1 in a patient with mental retardation and the fragile X syndrome phenotype.
-
Analysis of cDNA for human erythrocyte ankyrin indicates a repeated structure with homology to tissue-differentiation and cell-cycle control proteins.
-
Analysis of repetitive sequence elements containing tRNA-like sequences.
-
Analysis of the junction between ribosomal RNA genes and single-copy chromosomal sequences in the yeast Saccharomyces cerevisiae.
-
Angiotensin II can regulate gene expression by the AP-1 binding sequence via a protein kinase C-dependent pathway.
-
Antiangiogenic treatment with the three thrombospondin-1 type 1 repeats recombinant protein in an orthotopic human pancreatic cancer model.
-
COL5A1: fine genetic mapping and exclusion as candidate gene in families with nail-patella syndrome, tuberous sclerosis 1, hereditary hemorrhagic telangiectasia, and Ehlers-Danlos Syndrome type II.
-
Characterization of human brain cDNA encoding the general isoform of beta-spectrin.
-
Characterization of the transcriptional trans activator of human foamy retrovirus.
-
Characterization of the variable-number tandem repeats in vrrA from different Bacillus anthracis isolates.
-
Characterization of transcriptional activation and DNA-binding functions in the hinge region of the vitamin D receptor.
-
Chromosomal translocations generated by high-frequency meiotic recombination between repeated yeast genes.
-
Chromosome fragility at GAA tracts in yeast depends on repeat orientation and requires mismatch repair.
-
Cloning and characterization of DNA sequences surrounding the human gamma-, delta-, and beta-globin genes.
-
Combination gene therapy for liver metastasis of colon carcinoma in vivo.
-
Compact organization of rRNA genes in the filamentous fungus Ashbya gossypii.
-
Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution.
-
Complete genomic and epigenetic maps of human centromeres.
-
Complete vertebrate mitogenomes reveal widespread repeats and gene duplications.
-
Cowpox virus contains two copies of an early gene encoding a soluble secreted form of the type II TNF receptor.
-
DNA methylation of individual repetitive elements in hepatitis C virus infection-induced hepatocellular carcinoma.
-
DNA- and PCR-fingerprinting in fungi.
-
Delineation of the intronless nature of the genes for the human and hamster beta 2-adrenergic receptor and their putative promoter regions.
-
Dentatorubral-pallidoluysian atrophy and Haw River syndrome.
-
Dependence of the regulation of telomere length on the type of subtelomeric repeat in the yeast Saccharomyces cerevisiae.
-
Derivation and functional characterization of a consensus DNA binding sequence for the tas transcriptional activator of simian foamy virus type 1.
-
Destabilization of simple repetitive DNA sequences by transcription in yeast.
-
Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair.
-
Different models, different trees: the geographic origin of PTLV-I.
-
Differentiation of strains in Mycobacterium tuberculosis complex by DNA sequence polymorphisms, including rapid identification of M. bovis BCG.
-
Dinucleotide repeat polymorphism at the human erythropoietin receptor locus (EPOR) at 19p13.
-
Dinucleotide repeat polymorphisms at the SCN4A locus suggest allelic heterogeneity of hyperkalemic periodic paralysis and paramyotonia congenita.
-
Does the human immunodeficiency virus Tat trans-activator contain a discrete activation domain?
-
Drosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution.
-
Effect of allelic variation at the NACP-Rep1 repeat upstream of the alpha-synuclein gene (SNCA) on transcription in a cell culture luciferase reporter system.
-
Endogenous avian retroviruses contain deficient promoter and leader sequences.
-
Eukaryotic transcription termination factor La mediates transcript release and facilitates reinitiation by RNA polymerase III.
-
Evidence against equimolarity of large repeat arrangements and a predominant master circle structure of the mitochondrial genome from a monkeyflower (Mimulus guttatus) lineage with cryptic CMS.
-
Expanded polyglutamine domain proteins bind neurofilament and alter the neurofilament network.
-
Experimental determination of rates of concerted evolution.
-
Expression of a constitutive form of calcium/calmodulin dependent protein kinase II leads to arrest of the cell cycle in G2.
-
Formation of telomeric repeat-containing RNA (TERRA) foci in highly proliferating mouse cerebellar neuronal progenitors and medulloblastoma.
-
Functional analysis of the transcription control region located within the avian retroviral long terminal repeat.
-
Functional characterization of a complex protein-DNA-binding domain located within the human immunodeficiency virus type 1 long terminal repeat leader region.
-
Functional studies of the carboxy-terminal repeat domain of Drosophila RNA polymerase II in vivo.
-
Genetic and genomic evolution of sexual reproduction: echoes from LECA to the fungal kingdom.
-
Genetic control of chromosome length in yeast.
-
Genetic instability of microsatellites in endometrial carcinoma.
-
Genetic mapping of a gene causing hypertension in the stroke-prone spontaneously hypertensive rat.
-
Genetic mapping of dinucleotide repeat polymorphisms and von Hippel-Lindau disease on chromosome 3p25-26.
-
Genetic relationships and evolution of genotypes of yellow fever virus and other members of the yellow fever virus group within the Flavivirus genus based on the 3' noncoding region.
-
Glycosyl phosphatidylinositol-linked blood group antigens and paroxysmal nocturnal hemoglobinuria.
-
Guanine repeat-containing sequences confer transcription-dependent instability in an orientation-specific manner in yeast.
-
Hel-N1: an autoimmune RNA-binding protein with specificity for 3' uridylate-rich untranslated regions of growth factor mRNAs.
-
High-frequency meiotic gene conversion between repeated genes on nonhomologous chromosomes in yeast.
-
Histone gene clusters of the newt notophthalmus are separated by long tracts of satellite DNA.
-
Human and mouse alpha-synuclein genes: comparative genomic sequence analysis and identification of a novel gene regulatory element.
-
Human gamma-satellite DNA maintains open chromatin structure and protects a transgene from epigenetic silencing.
-
Human immunodeficiency virus type 1 rev protein as a negative trans-regulator.
-
Hypermutability and mismatch repair deficiency in RER+ tumor cells.
-
Identification and functional characterization of a high-affinity Bel-1 DNA binding site located in the human foamy virus internal promoter.
-
Identification of a U5-specific sequence required for efficient polyadenylation within the human immunodeficiency virus long terminal repeat.
-
Identification of a W variant outbreak of Mycobacterium tuberculosis via population-based molecular epidemiology.
-
Identification of a naturally occurring 21 bp deletion in alpha 2c noradrenergic receptor gene and cognitive correlates to antipsychotic treatment.
-
Identification of a new subclass of Alu DNA repeats which can function as estrogen receptor-dependent transcriptional enhancers.
-
Identification of a region of genetic variability among Bacillus anthracis strains and related species.
-
Identification of an X-ray induced deletion mutant flanked by direct repeats.
-
Identification of the sex genes in an early diverged fungus.
-
Identification of two regions of beta G spectrin that bind to distinct sites in brain membranes.
-
Identification of yeast mutants with altered telomere structure.
-
Importance of a c-Myb binding site for lymphomagenesis by the retrovirus SL3-3.
-
Inactivated whole-virus vaccine derived from a proviral DNA clone of simian immunodeficiency virus induces high levels of neutralizing antibodies and confers protection against heterologous challenge.
-
Inducible nitric oxide synthase (NOS2) promoter CCTTT repeat polymorphism: relationship to in vivo nitric oxide production/NOS activity in an asymptomatic malaria-endemic population.
-
Initial sequencing and analysis of the human genome.
-
Initial sequencing and comparative analysis of the mouse genome.
-
Instability of a plasmid-borne inverted repeat in Saccharomyces cerevisiae.
-
Instability of simple sequence DNA in Saccharomyces cerevisiae.
-
Instability of simple sequence repeats in a mammalian cell line.
-
Intrachromosomal gene conversion and the maintenance of sequence homogeneity among repeated genes.
-
Intrachromosomal gene conversion in yeast.
-
Intragenic duplication and divergence in the spectrin superfamily of proteins.
-
Inverted DNA repeats channel repair of distant double-strand breaks into chromatid fusions and chromosomal rearrangements.
-
Isolation and characterization of a Ty element inserted into the ribosomal DNA of the yeast Saccharomyces cerevisiae.
-
Isolation and characterization of cDNA clones encoding pig gastric mucin.
-
Isolation and characterization of the replicon of a Thiobacillus intermedius plasmid.
-
L-selectin binds to P-selectin glycoprotein ligand-1 on leukocytes: interactions between the lectin, epidermal growth factor, and consensus repeat domains of the selectins determine ligand binding specificity.
-
Linkage localization of X-linked Charcot-Marie-Tooth disease.
-
Linkage of a locus for autosomal dominant familial spastic paraplegia to chromosome 2p markers.
-
Linkage of frontotemporal dementia to chromosome 17: clinical and neuropathological characterization of phenotype.
-
Linkage of recessive familial amyotrophic lateral sclerosis to chromosome 2q33-q35.
-
Long poly(A) tracts in the human genome are associated with the Alu family of repeated elements.
-
Microsatellite instability in yeast: dependence on repeat unit size and DNA mismatch repair genes.
-
Mismatch repair deficiency in phenotypically normal human cells.
-
Mismatch repair proteins regulate heteroduplex formation during mitotic recombination in yeast.
-
Mitotic and meiotic gene conversion of Ty elements and other insertions in Saccharomyces cerevisiae.
-
Molecular analysis of recombination in a family with Duchenne muscular dystrophy and a large pericentric X chromosome inversion.
-
Mutational Dissection of Telomeric DNA Binding Requirements of G4 Resolvase 1 Shows that G4-Structure and Certain 3'-Tail Sequences Are Sufficient for Tight and Complete Binding.
-
Mutational analysis of the trans-activation-responsive region of the human immunodeficiency virus type I long terminal repeat.
-
Mutations in the MSH3 gene preferentially lead to deletions within tracts of simple repetitive DNA in Saccharomyces cerevisiae.
-
Nef protein of human immunodeficiency virus type 1: evidence against its role as a transcriptional inhibitor.
-
Nonconsensus Protein Binding to Repetitive DNA Sequence Elements Significantly Affects Eukaryotic Genomes.
-
Organization of ribosomal DNA in the basidiomycete Thanatephorus praticola.
-
P pili in uropathogenic E. coli are composite fibres with distinct fibrillar adhesive tips.
-
Parallel analysis of ribonucleotide-dependent deletions produced by yeast Top1 in vitro and in vivo.
-
Peripheral blood chimerism in renal allograft recipients transfused with donor bone marrow.
-
Polyglutamine domains are substrates of tissue transglutaminase: does transglutaminase play a role in expanded CAG/poly-Q neurodegenerative diseases?
-
Polymerase chain reaction fingerprinting in fungi using single primers specific to minisatellites and simple repetitive DNA sequences: strain variation in Cryptococcus neoformans.
-
Population dynamics of a meiotic/mitotic expansion model for the fragile X syndrome.
-
Positive patches and negative noodles: linking RNA processing to transcription?
-
Posttranscriptional regulation of protein expression in human epithelial carcinoma cells by adenine-uridine-rich elements in the 3'-untranslated region of tumor necrosis factor-alpha messenger RNA.
-
Prediction of genome-wide DNA methylation in repetitive elements.
-
Prevalence of incompletely penetrant Huntington's disease alleles among individuals with major depressive disorder.
-
Prevention of graft-versus-host disease by peptides binding to class II major histocompatibility complex molecules.
-
Probing the DNA sequence specificity of Escherichia coli RECA protein.
-
Protein-DNA binding in the absence of specific base-pair recognition.
-
Pseudomonas syringae pv. syringae harpinPss: a protein that is secreted via the Hrp pathway and elicits the hypersensitive response in plants.
-
RNA replication for the paramyxovirus simian virus 5 requires an internal repeated (CGNNNN) sequence motif.
-
Rapid genetic identification and mapping of enzymatically amplified ribosomal DNA from several Cryptococcus species.
-
Recent evolution of the human pathogen Cryptococcus neoformans by intervarietal transfer of a 14-gene fragment.
-
Recombination between palindromes P5 and P1 on the human Y chromosome causes massive deletions and spermatogenic failure.
-
Recombination of plasmids into the Saccharomyces cerevisiae chromosome is reduced by small amounts of sequence heterogeneity.
-
Regulation of mitotic homeologous recombination in yeast. Functions of mismatch repair and nucleotide excision repair genes.
-
Repeat polymorphisms within gene regions: phenotypic and evolutionary implications.
-
Replication control of autonomously replicating human sequences.
-
Replication of the murine cytomegalovirus genome: structure and role of the termini in the generation and cleavage of concatenates.
-
Retroviral vector gene expression in F9 embryonal carcinoma cells.
-
Retroviruses and human cancer: evaluation of T-lymphocyte transformation by human T-cell leukemia-lymphoma virus.
-
Saccharomyces cerevisiae RAD5-encoded DNA repair protein contains DNA helicase and zinc-binding sequence motifs and affects the stability of simple repetitive sequences in the genome.
-
Sequence of terminal regions of cowpox virus DNA: arrangement of repeated and unique sequence elements.
-
Sequencing and analysis of genomic fragments from the NF1 locus.
-
Seven-base-pair inverted repeats in DNA form stable hairpins in vivo in Saccharomyces cerevisiae.
-
Sp1, but not Sp3, functions to mediate promoter activation by TGF-beta through canonical Sp1 binding sites.
-
Specific 33-residue repeat(s) of erythrocyte ankyrin associate with the anion exchanger.
-
Spreading of X chromosome inactivation via a hierarchy of defined Polycomb stations.
-
Structural organization of the human insulin receptor ectodomain.
-
Structurally divergent human T cell receptor gamma proteins encoded by distinct C gamma genes.
-
Substrate length requirements for efficient mitotic recombination in Saccharomyces cerevisiae.
-
Suppression of leukaemia virus pathogenicity by polyoma virus enhancers.
-
Suppressor and activator functions mediated by a repeated heptad sequence in the liver fatty acid-binding protein gene (Fabpl). Effects on renal, small intestinal, and colonic epithelial cell gene expression in transgenic mice.
-
Tandemly repeated sequences are present at the ends of the DNA of raccoonpox virus.
-
The ANK repeats of erythrocyte ankyrin form two distinct but cooperative binding sites for the erythrocyte anion exchanger.
-
The Alacoil: a very tight, antiparallel coiled-coil of helices.
-
The DNA sequence of the human X chromosome.
-
The Haw River syndrome: dentatorubropallidoluysian atrophy (DRPLA) in an African-American family.
-
The MerR-like protein BldC binds DNA direct repeats as cooperative multimers to regulate Streptomyces development.
-
The Shortest Nucleosomal Repeat Lengths during Sea Urchin Development are Found in Two-Cell Embryos
-
The carboxyl-terminal repeat domain of RNA polymerase II is not required for transcription factor Sp1 to function in vitro.
-
The compact chromatin structure of a Ty repeated sequence suppresses recombination hotspot activity in Saccharomyces cerevisiae.
-
The human T-cell leukemia virus-1 transcriptional activator Tax enhances cAMP-responsive element-binding protein (CREB) binding activity through interactions with the DNA minor groove.
-
The human foamy virus Bel-1 transcription factor is a sequence-specific DNA binding protein.
-
The membrane-binding domain of ankyrin contains four independently folded subdomains, each comprised of six ankyrin repeats.
-
The pattern of gene amplification is determined by the chromosomal location of hairpin-capped breaks.
-
The rRNA-encoding DNA array has an altered structure in topoisomerase I mutants of Saccharomyces cerevisiae.
-
The role of avian retroviral LTRs in the regulation of gene expression and viral replication.
-
The role of the mismatch repair machinery in regulating mitotic and meiotic recombination between diverged sequences in yeast.
-
The stabilization of repetitive tracts of DNA by variant repeats requires a functional DNA mismatch repair system.
-
The western painted turtle genome, a model for the evolution of extreme physiological adaptations in a slowly evolving lineage.
-
Transcriptional activity of avian retroviral long terminal repeats directly correlates with enhancer activity.
-
Transcriptional interference in avian retroviruses--implications for the promoter insertion model of leukaemogenesis.
-
Translocation of Y-linked genes to the dot chromosome in Drosophila pseudoobscura.
-
Truncated forms of the insulin-like growth factor II (IGF-II)/mannose 6-phosphate receptor encompassing the IGF-II binding site: characterization of a point mutation that abolishes IGF-II binding.
-
Unusual chromosome architecture and behaviour at an HSR.
-
Utilization of a soluble integrin-alkaline phosphatase chimera to characterize integrin alpha 8 beta 1 receptor interactions with tenascin: murine alpha 8 beta 1 binds to the RGD site in tenascin-C fragments, but not to native tenascin-C.
-
Viral sequences determining the oncogenicity of avian leukosis viruses.
-
Viral sequences enable efficient and tissue-specific expression of transgenes in Xenopus.
-
Wild-type p53 is a cell cycle checkpoint determinant following irradiation.
-
α satellite DNA variation and function of the human centromere.
-
Keywords of People
-
Bennett, Vann,
George Barth Geller Distinguished Professor of Molecular Biology,
Duke Cancer Institute
-
Berchuck, Andrew,
James M. Ingram Distinguished Professor of Gynecologic Oncology,
Obstetrics and Gynecology, Gynecologic Oncology
-
Erickson, Harold Paul,
Professor Emeritus of Cell Biology,
Cell Biology
-
McDonnell, Donald Patrick,
Glaxo-Wellcome Distinguished Professor of Molecular Cancer Biology, in the School of Medicine,
Cell Biology