Respiratory Insufficiency

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  Subject Areas on Research

  • A Propensity-matched Survival Analysis: Do Simultaneous Liver-lung Transplant Recipients Need a Liver? 
  • A Rare Case of Isolated Congenital Asplenia Presenting in Septic Shock: Howell-Jolly Bodies a Clue to Early Diagnosis. 
  • A Systematic Review Evaluating Neuraxial Morphine and Diamorphine-Associated Respiratory Depression After Cesarean Delivery. 
  • A metabolomic endotype of bioenergetic dysfunction predicts mortality in critically ill patients with acute respiratory failure. 
  • A methodology to explore ventilatory chemosensitivity and opioid-induced respiratory depression risk. 
  • A retrospective assessment of the incidence of respiratory depression after neuraxial morphine administration for postcesarean delivery analgesia. 
  • A scoring system derived from electronic health records to identify patients at high risk for noninvasive ventilation failure. 
  • AAV9 gene replacement therapy for respiratory insufficiency in very-long chain acyl-CoA dehydrogenase deficiency. 
  • Acute Kidney Injury, Fluid Overload, and Outcomes in Children Supported With Extracorporeal Membrane Oxygenation for a Respiratory Indication. 
  • Acute Respiratory Failure in Pediatric Hematopoietic Cell Transplantation: A Multicenter Study. 
  • Acute exacerbations and respiratory failure in chronic obstructive pulmonary disease. 
  • Acute respiratory failure and the kinetics of neutrophil recovery in pediatric hematopoietic cell transplantation: a multicenter study. 
  • Adjunctive agents in systemic chemotherapy. 
  • Aerosol delivery in intubated, mechanically ventilated patients. 
  • Ambulatory ECMO as a bridge to lung transplant in a previously well pediatric patient with ARDS. 
  • American Thoracic Society/European Respiratory Society statement on pulmonary rehabilitation. 
  • Amyloid myopathy presenting with respiratory failure. 
  • Anesthetic management of the patient with extracorporeal membrane oxygenator support. 
  • Appropriate Use of High-Flow Nasal Oxygen in Hospitalized Patients for Initial or Postextubation Management of Acute Respiratory Failure: A Clinical Guideline From the American College of Physicians. 
  • Aspirated contrast material contributing to respiratory arrest in a pediatric trauma patient. 
  • Association between Respiratory Failure and Clinical Outcomes in Patients with Acute Heart Failure: Analysis of 5 Pooled Clinical Trials. 
  • Association between choice of reversal agent for neuromuscular block and postoperative pulmonary complications in patients at increased risk undergoing non-emergency surgery: STIL-STRONGER, a multicentre matched cohort study. 
  • Blockade of tissue factor-factor X binding attenuates sepsis-induced respiratory and renal failure. 
  • Bronchodilator S-nitrosothiol deficiency in asthmatic respiratory failure. 
  • Buprenorphine metabolites, buprenorphine-3-glucuronide and norbuprenorphine-3-glucuronide, are biologically active. 
  • Candida pneumonia in a term infant after prolonged use of inhaled corticosteroids for bronchopulmonary dysplasia (BPD). 
  • Carbon monoxide diffusion capacity: how low can you go for hematopoietic cell transplantation eligibility? 
  • Cardiac tamponade in a patient with chronic lymphocytic leukemia. 
  • Cascade iatrogenesis: a case-control study to detect postoperative respiratory failure in hospitalized older adults. 
  • Case 2: acute respiratory failure secondary to lymphangitic carcinomatosis. 
  • Catastrophic antiphospholipid syndrome with concurrent thrombotic and hemorrhagic manifestations. 
  • Central nervous system modulation of respiratory function in the critically ill. 
  • Clinical characteristics and outcomes of critically ill mechanically ventilated COVID-19 patients receiving interleukin-6 receptor antagonists and corticosteroid therapy: a preliminary report from a multinational registry. 
  • Co-morbidities Associated With Early Mortality in Adults With Spina Bifida. 
  • Commentaries on Viewpoint: Why do some patients stop breathing after taking narcotics? Ventilatory chemosensitivity as a predictor of opioid-induced respiratory depression. 
  • Commentary: Neonatal Extracorporeal Membrane Oxygenation: The More (Practice), The Merrier. 
  • Common postoperative pulmonary complications after hysterectomy for benign indications. 
  • Comparative safety profile of chloral hydrate versus other sedatives for procedural sedation in hospitalized infants. 
  • Comparing Presenting Clinical Features in 48 Children With Microscopic Polyangiitis to 183 Children Who Have Granulomatosis With Polyangiitis (Wegener's): An ARChiVe Cohort Study. 
  • Contemporary treatment of children with critical and near-fatal asthma. 
  • Continuing Non-Invasive Ventilation During Amyotrophic Lateral Sclerosis-Related Hospice Care Is Medically, Administratively, and Financially Feasible. 
  • Continuous oximetry/capnometry monitoring reveals frequent desaturation and bradypnea during patient-controlled analgesia. 
  • Correlation between the %MinVol setting and work of breathing during adaptive support ventilation in patients with respiratory failure. 
  • Correlation between transition percentage of minute volume (TMV%) and outcome of patients with acute respiratory failure. 
  • Corticosteroids improve survival of children with AIDS and Pneumocystis carinii pneumonia. 
  • Current issues in mechanical ventilation for respiratory failure. 
  • Cyclosporine or cyclosporine plus methylprednisolone for prophylaxis of graft-versus-host disease: a prospective, randomized trial. 
  • Definitions and epidemiology. 
  • Delirium is a robust predictor of morbidity and mortality among critically ill patients treated in the cardiac intensive care unit. 
  • Design and evaluation of a new, low pressure loss, implantable artificial lung. 
  • Developing a risk stratification tool for predicting opioid-related respiratory depression after non-cardiac surgery: a retrospective study. 
  • Diaphragmatic performance during recovery from acute ventilatory failure in Guillain-Barré syndrome and myasthenia gravis. 
  • Diffuse alveolar hemorrhage: retrospective review of clinical outcome in allogeneic transplant recipients treated with aminocaproic acid. 
  • Discontinuing mechanical ventilatory support: removing positive pressure ventilation vs removing the artificial airway. 
  • Does the clinical examination predict airflow limitation? 
  • Dual Procurement of Lung and Heart Allografts Does Not Negatively Affect Lung Transplant Outcomes. 
  • Effect of Discontinuing vs Continuing Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers on Days Alive and Out of the Hospital in Patients Admitted With COVID-19: A Randomized Clinical Trial. 
  • Effect of Vitamin C, Thiamine, and Hydrocortisone on Ventilator- and Vasopressor-Free Days in Patients With Sepsis: The VICTAS Randomized Clinical Trial. 
  • Effects of implementing adaptive support ventilation in a medical intensive care unit. 
  • Effects of mindfulness training programmes delivered by a self-directed mobile app and by telephone compared with an education programme for survivors of critical illness: a pilot randomised clinical trial. 
  • Effects of pressure support during an acute reduction of synchronized intermittent mandatory ventilation in preterm infants. 
  • Epidemiology and Outcomes of Patients Readmitted to the Intensive Care Unit After Cardiac Intensive Care Unit Admission. 
  • Estimated Global Proportions of Individuals With Persistent Fatigue, Cognitive, and Respiratory Symptom Clusters Following Symptomatic COVID-19 in 2020 and 2021. 
  • Evaluation of a new weaning index based on ventilatory endurance and the efficiency of gas exchange. 
  • Evidence-based guidelines for weaning and discontinuing ventilatory support: a collective task force facilitated by the American College of Chest Physicians; the American Association for Respiratory Care; and the American College of Critical Care Medicine. 
  • Evolution of the United States Military Extracorporeal Membrane Oxygenation Transport Team. 
  • Extracorporeal Membrane Oxygenation and Coronavirus Disease 2019. 
  • Extracorporeal Membrane Oxygenation for Hemodynamic Support. 
  • Extracorporeal Membrane Oxygenation in Pediatric Trisomy 21: 30 Years of Experience from the Extracorporeal Life Support Organization Registry. 
  • Extracorporeal membrane oxygenation for adult respiratory failure. 
  • Extracorporeal membrane oxygenation for neonatal and pediatric respiratory failure: an evidence-based review of the past decade (2002-2012). 
  • Extracorporeal membrane oxygenation for severe refractory respiratory failure secondary to 2009 H1N1 influenza A. 
  • Extracorporeal membrane oxygenation in critically ill neonatal and pediatric patients with acute respiratory failure: a guide for the clinician. 
  • Extracorporeal membrane oxygenation post lung transplantation. 
  • Factors associated with survival in pediatric extracorporeal membrane oxygenation--a single-center experience. 
  • Fulminant pertussis: a multi-center study with new insights into the clinico-pathological mechanisms. 
  • Fundoplication after lung transplantation prevents the allograft dysfunction associated with reflux. 
  • Gas exchange and exercise capacity affect neurocognitive performance in patients with lung disease. 
  • Heliox improves hemodynamics in mechanically ventilated patients with chronic obstructive pulmonary disease with systolic pressure variations. 
  • High-Flow Nasal Cannula in Pediatric Critical Asthma. 
  • High-Frequency Jet Ventilation in Infants With Congenital Heart Disease. 
  • High-Frequency Jet Ventilation in Neonatal and Pediatric Subjects: A Narrative Review. 
  • High-Frequency Jet Ventilation in Pediatric Acute Respiratory Failure. 
  • High-frequency jet ventilation. 
  • High-frequency oscillatory ventilation compared with conventional mechanical ventilation in the treatment of respiratory failure in preterm infants. 
  • How to handle myasthenic crisis. Essential steps in patient care. 
  • Humidified High-Flow Nasal Cannula Oxygen-More Than Just Supplemental Oxygen. 
  • Hypercoagulability and coronavirus disease 2019-associated hypoxemic respiratory failure: Mechanisms and emerging management paradigms. 
  • Hypoxia and Complications of Oxygenation in Extracorporeal Membrane Oxygenation. 
  • Hypoxic Gene Expression of Donor Bronchi Linked to Airway Complications after Lung Transplantation. 
  • Importance of trigger sensitivity to ventilator response delay in advanced chronic obstructive pulmonary disease with respiratory failure. 
  • Incidence and severity of acute complications after spinal cord injury. 
  • Index of suspicion. Case 1: Infant who has respiratory distress. Case 2: Abnormal behavior, seizures, and altered sensorium in a 7-year-old boy. Case 3: Fever and dysphagia in a 4-year-old girl. 
  • Inhaled PGE1 in neonates with hypoxemic respiratory failure: two pilot feasibility randomized clinical trials. 
  • Initial Noninvasive Oxygenation Strategies in Subjects With De Novo Acute Hypoxemic Respiratory Failure. 
  • Interhospital ECMO Transport: Regional Focus. 
  • Interleukin-1 receptor antagonist anakinra in association with remdesivir in severe COVID-19: A case report. 
  • Intracellular monitoring of experimental respiratory failure. Collaborative Group on Intracellular Monitoring. 
  • Intralingual Administration of AAVrh10-miRSOD1 Improves Respiratory But Not Swallowing Function in a Superoxide Dismutase-1 Mouse Model of Amyotrophic Lateral Sclerosis. 
  • Intravascular Gas Exchange: Physiology, Literature Review, and Current Efforts. 
  • Intravenous oxygen: a novel method of oxygen delivery in hypoxemic respiratory failure? 
  • Invasive Mechanical Ventilation and Mortality in Pediatric Hematopoietic Stem Cell Transplantation: A Multicenter Study. 
  • Invasive mechanical ventilation in adults: conference summary. 
  • Jet ventilation at 100 breaths per minute in adult respiratory failure. 
  • Last Word on Viewpoint: Why do some patients stop breathing after taking narcotics? Ventilatory chemosensitivity as a predictor of opioid-induced respiratory depression. 
  • Liquid ventilation. 
  • Long-term Neurocognitive Morbidity After a Single Episode of Respiratory Failure in Children. 
  • Low Incidence of Postoperative Respiratory Depression with Oliceridine Compared to Morphine: A Retrospective Chart Analysis. 
  • Lung protective ventilation: a summary of the current evidence from the 2012 American Association for Respiratory Care International Congress. 
  • Lung transplantation for Williams-Campbell syndrome. 
  • Macroglossia, Motor Neuron Pathology, and Airway Malacia Contribute to Respiratory Insufficiency in Pompe Disease: A Commentary on Molecular Pathways and Respiratory Involvement in Lysosomal Storage Diseases. 
  • Management of myxedematous respiratory failure: review of ventilation and weaning principles. 
  • Management of patients requiring prolonged mechanical ventilation: report of a NAMDRC consensus conference. 
  • Managing Respiratory Failure in Obstructive Lung Disease. 
  • Massive pulmonary edema and death after prostacyclin infusion in a patient with pulmonary veno-occlusive disease. 
  • Mechanical Ventilation and Clinical Outcomes in Patients with Acute Myocardial Infarction: A Retrospective Observational Study. 
  • Mechanical Ventilation and Respiratory Support in the Pediatric Intensive Care Unit. 
  • Mechanical loads on the ventilatory muscles. A theoretical analysis. 
  • Medical chart validation of inpatient diagnosis codes for transfusion-related acute lung injury 2013-2015. 
  • Monitoring, prevention and treatment of side effects of long-acting neuraxial opioids for post-cesarean analgesia. 
  • Mortality and Respiratory Failure After Thoracoscopic Lung Biopsy for Interstitial Lung Disease. 
  • Motor axonopathies in a mouse model of Duchenne muscular dystrophy. 
  • Motor neuron disease presenting with respiratory failure. Report of two cases. 
  • Myasthenia gravis: management of myasthenic crisis and perioperative care. 
  • Neuro-respiratory pathology in spinocerebellar ataxia. 
  • Noninvasive Oxygenation Strategies in Immunocompromised Patients With Acute Hypoxemic Respiratory Failure: A Pairwise and Network Meta-Analysis of Randomized Controlled Trials. 
  • Noninvasive Ventilation Exposure Prior to Intubation in Pediatric Hematopoietic Cell Transplant Recipients. 
  • Noninvasive ventilation in the emergency department: insights on implementation bias and evidence. 
  • Nutrition care of patients with acute and chronic respiratory failure. 
  • Occurrence and complications of tracheal reintubation in critically ill adults. 
  • Ocular toxicity following high dose chemotherapy and autologous transplant. 
  • Of Goldilocks and ventilatory muscle loading. 
  • Opioid-related respiratory and gastrointestinal adverse events in patients with acute postoperative pain: prevalence, predictors, and burden. 
  • Optimal NIV Medicare Access Promotion: Patients With COPD: A Technical Expert Panel Report From the American College of Chest Physicians, the American Association for Respiratory Care, the American Academy of Sleep Medicine, and the American Thoracic Society. 
  • Optimal NIV Medicare Access Promotion: Patients With Thoracic Restrictive Disorders: A Technical Expert Panel Report From the American College of Chest Physicians, the American Association for Respiratory Care, the American Academy of Sleep Medicine, and the American Thoracic Society. 
  • Optimal timing of tracheostomy after trauma without associated head injury. 
  • Outcomes after esophagectomy: a ten-year prospective cohort. 
  • Outcomes of stem cell transplant patients with acute respiratory failure requiring mechanical ventilation in the United States. 
  • Paraquat ingestion: a challenging diagnosis. 
  • Patient-controlled analgesia. 
  • Patient-ventilator interactions. Implications for clinical management. 
  • Patient-ventilator synchrony during pressure-targeted versus flow-targeted small tidal volume assisted ventilation. 
  • Patient-ventilator trigger dys-synchrony: a common phenomenon with important implications. 
  • Pediatric acute respiratory failure: areas of debate in the pediatric critical care setting. 
  • Percutaneous renal biopsy of ventilated intensive care unit patients. 
  • Perioperative pulmonary function in acute respiratory failure: effect of ventilator type and gas mixture. 
  • Persistent endotracheal tube cuff overdistension: a sign of tracheomalacia. 
  • Physiologic Effects of Noninvasive Ventilation. 
  • Point-of-care washing of allogeneic red blood cells for the prevention of transfusion-related respiratory complications (WAR-PRC): a protocol for a multicenter randomised clinical trial in patients undergoing cardiac surgery. 
  • Postoperative Pulmonary Complications, Early Mortality, and Hospital Stay Following Noncardiothoracic Surgery: A Multicenter Study by the Perioperative Research Network Investigators. 
  • Postoperative oxycodone toxicity in a patient with chronic pain and end-stage renal disease. 
  • Postpartum Respiratory Depression. 
  • Practical Recommendations for Diagnosis and Management of Respiratory Muscle Weakness in Late-Onset Pompe Disease. 
  • Pre-transplant weight loss and clinical outcomes after lung transplantation. 
  • Predicting the Risk of Postoperative Respiratory Failure in Elective Abdominal and Vascular Operations Using the National Surgical Quality Improvement Program (NSQIP) Participant Use Data File. 
  • Preoperative preparation of patients with myasthenia gravis forestalls postoperative respiratory complications after thymectomy. 
  • Prevalence of Reintubation Within 24 Hours of Extubation in Bronchiolitis: Retrospective Cohort Study Using the Virtual Pediatric Systems Database. 
  • Prevalence, Risk Factors, and Outcomes of Financial Stress in Survivors of Critical Illness. 
  • Preventive use of noninvasive ventilation after extubation: a prospective, multicenter randomized controlled trial. 
  • Progress and perspectives in pediatric acute respiratory distress syndrome. 
  • Protocolized Postextubation Respiratory Support to Prevent Reintubation: A Randomized Clinical Trial. 
  • Psychosocial issues in the assessment and management of patients undergoing lung transplantation. 
  • Pulmonary Artery Catheter Consensus conference: consensus statement. 
  • Pulmonary Edema and Hypoxic Respiratory Failure. 
  • Pulmonary function in preterm infants whose lungs were ventilated conventionally or by high-frequency oscillation. 
  • Pulmonary hemorrhage syndrome as a manifestation of disseminated intravascular coagulation: analysis of ten cases. 
  • Qualifying Patients for Noninvasive Positive Pressure Ventilation Devices on Hospital Discharge. 
  • Rapid clinical assessment of patients with acute heart failure: first blood pressure and oxygen saturation--is that all we need? 
  • Recommendations for rescue of a submerged unresponsive compressed-gas diver. 
  • Reply to Drs. Wang et al. 
  • Rescue therapy in adult and pediatric patients with pH1N1 influenza infection: a tertiary center intensive care unit experience from April to October 2009. 
  • Respiratory Compromise as a New Paradigm for the Care of Vulnerable Hospitalized Patients. 
  • Respiratory Effects of the Atypical Tricyclic Antidepressant Tianeptine in Human Models of Opioid-induced Respiratory Depression. 
  • Respiratory depression after administration of single-dose neuraxial morphine for post-cesarean delivery analgesia: a retrospective cohort study. 
  • Respiratory depression requiring ventilatory support following 0.5 mg of triazolam. 
  • Respiratory distress adversely affects the outcome of childhood cerebral malaria. 
  • Respiratory dysfunction in Guillain-Barré syndrome. 
  • Respiratory failure early after lung transplantation: now that we know the extent of the problem, what are the solutions? 
  • Respiratory pathogens associated with intubated pediatric patients following hematopoietic cell transplant. 
  • Respiratory pathology in the Optn-/- mouse model of Amyotrophic Lateral Sclerosis. 
  • Right heart catheterization in acute respiratory failure. 
  • Safety and side-effect profile of intrathecal morphine in a diverse patient population undergoing total knee and hip arthroplasty. 
  • Short-Term Adverse Outcomes Associated With Hypoglycemia in Critically Ill Children. 
  • Society for Obstetric Anesthesia and Perinatology Consensus Statement: Monitoring Recommendations for Prevention and Detection of Respiratory Depression Associated With Administration of Neuraxial Morphine for Cesarean Delivery Analgesia. 
  • State of the art: strategies for extracorporeal membrane oxygenation in respiratory failure. 
  • Successful extracorporeal membrane oxygenation for respiratory failure in an infant with DiGeorge anomaly, following thymus transplantation. 
  • Successful use of extracorporeal membrane oxygenation in a child with obstructive shock due to massive bilateral pulmonary embolism. 
  • Supporting oxygenation in acute respiratory failure. 
  • Surgical management of aortic abdominal aneurysms in patients with severe pulmonary insufficiency. 
  • Survey of methadone-drug interactions among patients of methadone maintenance treatment program in Taiwan. 
  • Technological advances in extracorporeal membrane oxygenation for respiratory failure. 
  • Testing of an intrathoracic artificial lung in a pig model. 
  • The ARREST Pneumonia Clinical Trial. Rationale and Design. 
  • The Challenges of Identifying an Oxygenation Index Threshold for Increased Mortality in Pediatric Acute Respiratory Failure. 
  • The changing epidemiology of mechanical ventilation: a population-based study. 
  • The management of myasthenia gravis in pregnancy. 
  • The number of tracheal intubation attempts matters! A prospective multi-institutional pediatric observational study. 
  • The science of neonatal high-frequency ventilation. 
  • The use of high-flow nasal cannula in the pediatric emergency department. 
  • Thoracoscopic lobectomy: a safe and effective strategy for patients receiving induction therapy for non-small cell lung cancer. 
  • Thymoma and myasthenia gravis in a 4-year-old child. Case report and review of the literature. 
  • Timing of Treatment Outcomes and Risk Factors for Failure of BPAP in Patients Hospitalized for COPD Exacerbation. 
  • Tracheostomy After Operations for Congenital Heart Disease: An Analysis of the Society of Thoracic Surgeons Congenital Heart Surgery Database. 
  • Tracheostomy After Severe Acute Brain Injury: Trends and Variability in the USA. 
  • Tracheostomy Practices and Outcomes in Children During Respiratory Extracorporeal Membrane Oxygenation. 
  • Tracheostomy for COVID-19 Respiratory Failure: Multidisciplinary, Multicenter Data on Timing, Technique, and Outcomes. 
  • Training, detraining, and retraining: Two 12-week respiratory muscle training regimens in a child with infantile-onset Pompe disease. 
  • Transesophageal echocardiography of pulmonary thrombus causing complete left pulmonary artery occlusion. 
  • Transoral Sclerotherapy for Deep Space Cervical Lymphatic Malformations in Children With Acute Airway Compromise. 
  • UNUSUAL NEUROLOGICAL AND CARDIOVASCULAR COMPLICATIONS OF RESPIRATORY FAILURE. 
  • Use of extracorporeal life support in adults with severe acute respiratory failure. 
  • Ventilator advisory system employing load and tolerance strategy recommends appropriate pressure support ventilation settings: multisite validation study. 
  • Ventilatory drive and carbon dioxide response in ventilatory failure due to myasthenia gravis and Guillain-Barré syndrome. 
  • Ventilatory management in critical neurologic illness. 
  • Video-assisted wedge resection and local radiotherapy for peripheral lung cancer in high-risk patients: the Cancer and Leukemia Group B (CALGB) 9335, a phase II, multi-institutional cooperative group study. 
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  Keywords of People

  • Al-Hegelan, Mashael, Associate Professor of Medicine, Medicine, Pulmonary, Allergy, and Critical Care Medicine
  • Anderson, Ruth A., Professor Emerita in the School of Nursing, School of Nursing
  • Dominguez, Jennifer Estrella, Associate Professor of Anesthesiology, Anesthesiology, Women's
  • Mallory, Palen Powelson, Assistant Professor of Pediatrics, Pediatrics, Critical Care Medicine
  • O'Connor, Christopher Michael, Adjunct Professor in the Department of Medicine, Medicine, Clinical Pharmacology
  • Turner, David Ashley, Consulting Professor in the Department of Pediatrics, Pediatrics, Critical Care Medicine
  • Wu, Li-Tzy, Professor in Psychiatry and Behavioral Sciences, Medicine, General Internal Medicine