Retroviridae Infections

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  Subject Areas on Research

  • Alternative approaches for the application of ribozymes as gene therapies for retroviral infections. 
  • Antibody-dependent enhancement of simian immunodeficiency virus (SIV) infection in vitro by plasma from SIV-infected rhesus macaques. 
  • CD4+Thy1- thymocytes with a Th-type 2 cytokine response. 
  • Characterization of Rhesus Macaque Liver-Resident CD49a+ NK Cells During Retrovirus Infections. 
  • Complement-mediated, infection-enhancing antibodies in plasma from vaccinated macaques before and after inoculation with live simian immunodeficiency virus. 
  • Current status and strategies for vaccines against diseases induced by human T-cell lymphotropic retroviruses (HTLV-I, -II, -III). 
  • Enhanced type 1 immunity after secondary viral challenge in mice primed as neonates. 
  • Evidence against transmission of human T-lymphotropic virus/lymphadenopathy-associated virus (HTLV-III/LAV) in families of children with the acquired immunodeficiency syndrome. 
  • Expression of transfected DNA in avian cells can be enhanced in trans by retroviral infection. 
  • IFN-gamma production in response to neuropathogenic Cas-Br-M murine leukemia virus infection. 
  • Identification of novel, highly expressed retroviral microRNAs in cells infected by bovine foamy virus. 
  • In vivo hypermutation of xenotropic murine leukemia virus-related virus DNA in peripheral blood mononuclear cells of rhesus macaque by APOBEC3 proteins. 
  • Induction of protective CTL responses in newborn mice by a murine retrovirus. 
  • Is MMTV associated with human breast cancer? Maybe, but probably not. 
  • Local production of TGF beta1 inhibits cerebral edema, enhances TNF-alpha induced apoptosis and improves survival in a murine glioma model. 
  • Molecular ecology and natural history of simian foamy virus infection in wild-living chimpanzees. 
  • Monoclonal antibodies against human T cell leukemia-lymphoma virus (HTLV) p24 internal core protein. Use as diagnostic probes and cellular localization of HTLV. 
  • Monoclonal antibodies reactive with human T cell lymphotropic virusI (HTLVI) p19 internal core protein: cross-reactivity with normal tissues and differential reactivity with HTLV types I and II. 
  • Multiple sclerosis, retroviruses, and PCR. The HTLV-MS Working Group. 
  • Neonatal W-mutant mice are favorable hosts for tracking development of marked hematopoietic stem cells. 
  • Neonate-primed CD8+ memory cells rival adult-primed memory cells in antigen-driven expansion and anti-viral protection. 
  • Prevalence of HTLV-I-associated T-cell lymphoma. 
  • Progress in vaccine development against SIV and HIV. 
  • Prospects for development of a vaccine against HTLV-III-related disorders. 
  • Prospects for treatment of human retrovirus-associated diseases. 
  • Retroviral E-DNA: persistence and gene expression in nondividing immune cells. 
  • Retroviruses and human cancer: evaluation of T-lymphocyte transformation by human T-cell leukemia-lymphoma virus. 
  • Strategies of antiretroviral therapy in adults. 
  • Synthetic autoantigens of immunoglobulins and T-cell receptors: their recognition in aging, infection, and autoimmunity. 
  • Therapeutic effects of diethylcarbamazine and 3'-azido-3'-deoxythymidine on feline leukemia virus lymphoma formation. 
  • Ultraviolet-light-inactivated Cas-Br-M murine leukemia virus induces a protective CD8+ cytotoxic T lymphocyte response in newborn mice. 
  • Use of antiretroviral therapy in children and pregnant women. 
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  Keywords of People

  • Cianciolo, George James, Associate Professor Emeritus of Pathology, Pathology
  • Sampson, John Howard, Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine, Biomedical Engineering
  • Weinhold, Kent James, Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery, Immunology