RNA-Directed DNA Polymerase
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Subject Areas on Research
- 3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro.
- A comparison of methods for RNA extraction from lymphocytes for RT-PCR.
- A method for analysis of gene expression patterns.
- A novel species-specific RNA related to alternatively spliced amyloid precursor protein mRNAs.
- A soluble inhibitor of T lymphocyte function induced by HIV-1 infection of CD4+ T cells: characterization of a cellular protein and its relationship to p15E.
- Anti-AIDS agents. 15. Synthesis and anti-HIV activity of dihydroseselins and related analogs.
- Anti-human immunodeficiency virus synergism by zidovudine (3'-azidothymidine) and didanosine (dideoxyinosine) contrasts with their additive inhibition of normal human marrow progenitor cells.
- Antibody-dependent enhancement of human immunodeficiency virus type 1 (HIV-1) infection in vitro by serum from HIV-1-infected and passively immunized chimpanzees.
- Antibody-independent, complement-mediated enhancement of HIV-1 infection by mannosidase I and II inhibitors.
- Antiretroviral monotherapy in early stage human immunodeficiency virus disease has no detectable effect on virus load in peripheral blood and lymph nodes.
- Association of the viral reverse transcriptase with an enzyme degrading the RNA moiety of RNA-DNA hybrids.
- Betulinic acid and dihydrobetulinic acid derivatives as potent anti-HIV agents.
- Complement-mediated, antibody-dependent enhancement of HIV-1 infection in vitro is characterized by increased protein and RNA syntheses and infectious virus release.
- Cytokine expression by models of human trophoblast as assessed by a semiquantitative reverse transcription-polymerase chain reaction technique.
- DNA polymerases versus HIV reverse transcriptase in AIDS therapy.
- Detection of sequences homologous to human retroviral DNA in multiple sclerosis by gene amplification.
- Differential collagen I gene expression in fetal fibroblasts.
- Differential inhibition of HIV-1 cell binding and HIV-1-induced syncytium formation by low molecular weight sulphated polysaccharides.
- Drug resistance and HCV coinfection in former blood donors infected with HIV type 1 in China.
- Evidence of mRNA-mediated intron loss in the human-pathogenic fungus Cryptococcus neoformans.
- Evolutionarily conserved epitopes on human immunodeficiency virus type 1 (HIV-1) and feline immunodeficiency virus reverse transcriptases detected by HIV-1-infected subjects.
- Evolutionary implications of primate endogenous retroviruses.
- Frequent detection and isolation of cytopathic retroviruses (HTLV-III) from patients with AIDS and at risk for AIDS.
- High-Frequency Illegitimate Strand Transfers of Nascent DNA Fragments During Reverse Transcription Result in Defective Retrovirus Genomes.
- Homotypic antibody responses to fresh clinical isolates of human immunodeficiency virus.
- In vitro assays for detecting neutralizing and fusion-inhibiting antibodies to SIVMAC251.
- In vitro selection and characterization of human immunodeficiency virus type 2 with decreased susceptibility to lopinavir.
- Incorporation of (alpha-P-borano)-2',3'-dideoxycytidine 5'-triphosphate into DNA by drug-resistant MMLV reverse transcriptase and Taq DNA polymerase.
- Initiation of antiretroviral therapy during primary HIV-1 infection induces rapid stabilization of the T-cell receptor beta chain repertoire and reduces the level of T-cell oligoclonality.
- Kinetic mechanism of the DNA-dependent DNA polymerase activity of human immunodeficiency virus reverse transcriptase.
- Lack of enhancing effect of human anti-human immunodeficiency virus type 1 (HIV-1) antibody on HIV-1 infection of human blood monocytes and peritoneal macrophages.
- Letter: Role of reverse transcriptase.
- Misincorporation and mispaired primer extension by human immunodeficiency virus reverse transcriptase.
- Molecular genetic and immunohistochemical analysis of the tumor suppressor genes Rb and p53 in palmar and aggressive fibromatosis.
- Multiprotein HIV type 1 clade B DNA and MVA vaccines: construction, expression, and immunogenicity in rodents of the MVA component.
- Oligoclonal CD8 lymphocytes from persons with asymptomatic human immunodeficiency virus (HIV) type 1 infection inhibit HIV-1 replication.
- Ovalbumin gene: purification of the coding strand.
- Patterns of HIV-1 mRNA expression in transgenic mice are tissue-dependent.
- Porcine granulosa cells do not express transforming growth factor-beta 2 (TGF-beta 2) messenger ribonucleic acid: molecular basis for their inability to produce TGF-beta activity comparable to that of rat granulosa cells.
- Productive human immunodeficiency virus type 1 (HIV-1) infection of nonproliferating human monocytes.
- Prolonged tenofovir treatment of macaques infected with K65R reverse transcriptase mutants of SIV results in the development of antiviral immune responses that control virus replication after drug withdrawal.
- Properties of prostatic cultures transformed by SV40.
- Purification of a terminal uridylyltransferase that acts as host factor in the in vitro poliovirus replicase reaction.
- Rapid 16S ribosomal DNA sequencing from a single colony without DNA extraction or purification.
- Rat thecal/interstitial cells express transforming growth factor-beta type 1 and 2, but only type 2 is regulated by gonadotropin in vitro.
- Restricted neutralization of divergent human T-lymphotropic virus type III isolates by antibodies to the major envelope glycoprotein.
- Role of conserved gp41 cysteine residues in the processing of human immunodeficiency virus envelope precursor and viral infectivity.
- Selective antiviral activity of synthetic soluble L-tyrosine and L-dopa melanins against human immunodeficiency virus in vitro.
- Simultaneous amplification of four DNA repair genes and beta-actin in human lymphocytes by multiplex reverse transcriptase-PCR.
- Structural components of avian myeloblastosis virus.
- Structural components of rna tumor viruses.
- Structure and morphogenesis of type-C retroviruses.
- Synthesis of (3H)DNA complementary to ovalbumin messenger RNA: evidence for limited copies of the ovalbumin gene in chick oviduct.
- Synthesis of 5-(1-propynyl)-2'-deoxyuridine 5'-(alpha-P-borano)triphosphate and kinetic characterization as a substrate for mmlv reverse transcriptase.
- Synthesis of acyclothymidine triphosphate and alpha-P-boranotriphosphate and their substrate properties with retroviral reverse transcriptase.
- Synthesis of single-stranded hybridization probes from reusable DNA templates bound to solid support.
- The case for a family of reverse transcriptase viruses: Retraviridae.
- The initial nucleotide sequence of DNA transcribed from avian myeloblastosis virus 70 S RNA by RNA-dependent DNA polymerase.
- Two DNA polymerases: HIV reverse transcriptase and the Klenow fragment of Escherichia coli DNA polymerase I.
- Use of a specific probe for ovalbumin messenger RNA to quantitate estrogen-induced gene transcripts.
- [Morphogenesis and structure of RNA tumor viruses. Electron microscopy studies on C-type viruses].
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Keywords of People
- Ferrari, Guido, Professor in Surgery, Molecular Genetics and Microbiology
- Weinhold, Kent James, Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery, in the School of Medicine, Immunology