Rheology

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  Subject Areas on Research

  • A Microfluidic System with Surface Patterning for Investigating Cavitation Bubble(s)-Cell Interaction and the Resultant Bioeffects at the Single-cell Level. 
  • A hybrid polymer gel with controlled rates of cross-link rupture and self-repair. 
  • A novel ultrasound-based method to evaluate hemostatic function of whole blood. 
  • A work-performing heart preparation for myocardial performance analysis in murine hearts. 
  • Adaptive force sonorheometry for assessment of whole blood coagulation. 
  • Alterations in the rheological flow profile in conduit femoral artery during rhythmic thigh muscle contractions in humans. 
  • Altered intravascular contrast material flow dynamics: clues for refining thoracic CT diagnosis. 
  • An analytic, Fourier domain description of shear wave propagation in a viscoelastic medium using asymmetric Gaussian sources. 
  • Angiojet rheolytic thrombectomy in infants following cardiac surgery. 
  • Angle independent ultrasonic blood flow detection by frame-to-frame correlation of B-mode images. 
  • Angle independent ultrasonic detection of blood flow. 
  • Anxiety and cerebral blood flow. 
  • Bioelectrorheological model of the cell. 5. Electrodestruction of cellular membrane in alternating electric field. 
  • Blood flow distribution in sorbent beds: analysis of a new sorbent device for hemoperfusion. 
  • Blood-induced arterial segmental spasm. 
  • CHST1 and CHST2 sulfotransferase expression by vascular endothelial cells regulates shear-resistant leukocyte rolling via L-selectin. 
  • Cardiac fatigue after prolonged exercise. 
  • Cardiovascular correlates of the psychotherapeutic process. 
  • Catheter-based intracoronary myocardial adenoviral gene delivery: importance of intraluminal seal and infusion flow rate. 
  • Cell adhesion peptides alter smooth muscle cell adhesion, proliferation, migration, and matrix protein synthesis on modified surfaces and in polymer scaffolds. 
  • Cell mechanics: dissecting the physical responses of cells to force. 
  • Central venous catheter integrity during mechanical power injection of iodinated contrast medium. 
  • Characterization of a genetically engineered elastin-like polypeptide for cartilaginous tissue repair. 
  • Circulating Tumor Cell Phenotyping via High-Throughput Acoustic Separation. 
  • Coagulation-induced resistance to fluid flow in small-diameter vascular grafts and graft mimics measured by purging pressure. 
  • Coefficient of restitution for wet particles. 
  • Color flow-encoded MR imaging. 
  • Combined macro- and microrheometer for use with Langmuir monolayers. 
  • Comparison of real and idealized cetacean flippers. 
  • Comparison of renal function following anesthesia with low-flow sevoflurane and isoflurane. 
  • Comparison of the rheological properties of Advantage-S and Replens. 
  • Computer-assisted modeling of blood-flow: theoretical evidence for the existence of optimal flow wave patterns. 
  • Control of Mesh Size and Modulus by Kinetically Dependent Cross-Linking in Hydrogels. 
  • Differentiation of mammalian skeletal muscle cells cultured on microcarrier beads in a rotating cell culture system. 
  • Dilution of microbicide gels with vaginal fluid and semen simulants: effect on rheological properties and coating flow. 
  • Dissociation between global and regional systolic and diastolic ventricular function during coronary occlusion and reperfusion. 
  • Dorsal root ganglia neurite extension is inhibited by mechanical and chondroitin sulfate-rich interfaces. 
  • Dynamics of tandem bubble interaction in a microfluidic channel. 
  • Effect of temperature and pH on contraceptive gel viscosity. 
  • Effects of menstrual cycle and urinary tract instrumentation on uroflowmetry. 
  • Effects of turbulence on signal intensity in gradient echo images. 
  • Establishment of normal ranges of laser Doppler blood flow in autologous tissue transplants. 
  • Experimental velocity profiles and volumetric flow via two-dimensional speckle tracking. 
  • Feedback-tracking microrheology in living cells. 
  • Flow patterns and heat convection in a rectangular water bolus for use in superficial hyperthermia. 
  • Flow stabilization with active hydrodynamic cloaks. 
  • Fluctuation-dissipation theorem in an aging colloidal glass. 
  • Gold nanorods as a contrast agent for Doppler optical coherence tomography. 
  • Gravity-induced coating flows of vaginal gel formulations: in vitro experimental analysis. 
  • Hemodynamic stress and experimental aortoiliac atherosclerosis. 
  • High-resolution microrheology in the pericellular matrix of prostate cancer cells. 
  • High-resolution probing of cellular force transmission. 
  • Human cervical mucus: research update. 
  • IL-1beta sensitizes intervertebral disc annulus cells to fluid-induced shear stress. 
  • Identification of material properties of orthotropic elastic cylinders immersed in fluid using vibroacoustic techniques. 
  • Improved uniformity of aortic enhancement with customized contrast medium injection protocols at CT angiography. 
  • In vitro calculation of flow by use of contrast ultrasonography. 
  • In vitro functional testing of endothelial progenitor cells that overexpress thrombomodulin. 
  • In vitro temperature map of cardiac ablation demonstrates the effect of flow on lesion development. 
  • In vitro ultrasonic imaging of flow through prosthetic heart valves. 
  • In vivo cardiac, acoustic-radiation-force-driven, shear wave velocimetry. 
  • In vivo optically encoded photoacoustic flowgraphy. 
  • In vivo photoacoustic imaging of transverse blood flow by using Doppler broadening of bandwidth. 
  • Increased yield of endothelial cells from peripheral blood for cell therapies and tissue engineering. 
  • Laser Doppler monitoring of replants using a small prism probe. 
  • Laser-induced heating in optical traps. 
  • Late-outgrowth endothelial progenitors from patients with coronary artery disease: endothelialization of confluent stromal cell layers. 
  • Leukocyte rolling velocities and migration are optimized by cooperative L-selectin and intercellular adhesion molecule-1 functions. 
  • Linear and nonlinear rheology of liberase-treated breast cancer tumors. 
  • Local control of microvascular function: role in tissue oxygen supply. 
  • Mean scalar concentration profile in a sheared and thermally stratified atmospheric surface layer. 
  • Measurement of aortic blood flow in man by the computed pressure derivative method. 
  • Measurement of erythrocyte velocity by use of a periodic differential detector. 
  • Mechanical evidence of cervical facet capsule injury during whiplash: a cadaveric study using combined shear, compression, and extension loading. 
  • Mechanical responsiveness of the endothelial cell of Schlemm's canal: scope, variability and its potential role in controlling aqueous humour outflow. 
  • Metabolic requirements of contractile force generation in platelet rich plasma - a rheological study. 
  • Microporous annealed particle hydrogel stiffness, void space size, and adhesion properties impact cell proliferation, cell spreading, and gene transfer. 
  • Microrheology of hyaluronan solutions: implications for the endothelial glycocalyx. 
  • Microrheology probes length scale dependent rheology. 
  • Microrheology, stress fluctuations, and active behavior of living cells. 
  • Microvascular determinants of blood flow. 
  • Multifactorial optimization of endothelial cell growth using modular synthetic extracellular matrices. 
  • Multiple-particle tracking and two-point microrheology in cells. 
  • NMR rheotomography: feasibility and clinical potential. 
  • Non-linear viscoelastic properties of cervical mucus. 
  • Nonequilibrium mechanics of active cytoskeletal networks. 
  • Noninvasive screening for intracranial hypertension in children with acute, severe traumatic brain injury. 
  • Optical Phase Measurements of Disorder Strength Link Microstructure to Cell Stiffness. 
  • Optical imaging and analysis of human vaginal coating by drug delivery gels 
  • Phase aberration correction using echo signals from moving targets. I: Description and theory. 
  • Phase aberration correction using echo signals from moving targets. II: Experimental system and results. 
  • Photoacoustic thermal flowmetry with a single light source. 
  • Physical principles governing the interrelationships of pressure, flow and volume in collapsible tubes. 
  • Pigtail catheters used for percutaneous fluid drainage: comparison of performance characteristics. 
  • Protein polymer hydrogels by in situ, rapid and reversible self-gelation. 
  • Pulmonary vascular impedance analysis of adaptation to chronically elevated blood flow in the awake dog. 
  • Quantitation of vascular outflow by measurement of impedance. 
  • RNA Controls PolyQ Protein Phase Transitions. 
  • Rapid flow of passive neutrophils into a 4 microns pipet and measurement of cytoplasmic viscosity. 
  • Real-time in vivo color Doppler optical coherence tomography. 
  • Rheological properties of contraceptive gels. 
  • Rheological properties of cysteine-containing elastin-like polypeptide solutions and hydrogels. 
  • Rheological properties of living cytoplasm: a preliminary investigation of squid axoplasm (Loligo pealei). 
  • Rheological properties of living cytoplasm: endoplasm of Physarum plasmodium. 
  • Roles of mucus adhesion and cohesion in cough clearance. 
  • Round versus flat: bone cell morphology, elasticity, and mechanosensing. 
  • Routine clinical use of laser Doppler flowmeter to monitor free tissue transfer: preliminary results. 
  • Shear Modulus Measurement by Quantitative Phase Imaging and Correlation with Atomic Force Microscopy. 
  • Shear stress elevates endothelial cGMP. Role of a potassium channel and G protein coupling. 
  • Single-pass volumetric bidirectional blood flow imaging spectral domain optical coherence tomography using a modified Hilbert transform. 
  • Sonorheometry: a noncontact method for the dynamic assessment of thrombosis. 
  • Streptokinase-induced degradation of crosslinked and uncrosslinked clots. 
  • Suitability of lattice Boltzmann inlet and outlet boundary conditions for simulating flow in image-derived vasculature. 
  • Surgeon judgment and utility of transit time flow probes in coronary artery bypass grafting surgery. 
  • Sustained release of antibiotics from injectable and thermally responsive polypeptide depots. 
  • Tenascin supports lymphocyte rolling. 
  • The biocompatibility of titanium cardiovascular devices seeded with autologous blood-derived endothelial progenitor cells: EPC-seeded antithrombotic Ti implants. 
  • The changing paradigm of outflow resistance generation: towards synergistic models of the JCT and inner wall endothelium. 
  • The consensus mechanics of cultured mammalian cells 
  • The constructal law of organization in nature: tree-shaped flows and body size. 
  • The effect of aging on low-fat, reduced-fat, and full-fat Cheddar cheese texture. 
  • The effect of flunarizine on erythrocyte suspension viscosity under conditions of extreme hypoxia, low pH, and lactate treatment. 
  • The effect of pentoxifylline on retinal capillary blood flow velocity and whole blood viscosity. 
  • The role of adhesion molecules in human leukocyte attachment to porcine vascular endothelium: implications for xenotransplantation. 
  • The use of gradient flow compensation to separate diffusion and microcirculatory flow in MRI. 
  • Titanium with aligned, elongated pores for orthopedic tissue engineering applications. 
  • Two phenomenological constants explain similarity laws in stably stratified turbulence. 
  • Ultrasound-heated photoacoustic flowmetry. 
  • Using rheology to quantify the effects of localized collagenase treatments on uterine fibroid digestion. 
  • Vaginal administration of low-dose conjugated estrogens: systemic absorption and effects on the endometrium. 
  • Viscoelastic response of a model endothelial glycocalyx. 
  • Water mobility within bovine cervical mucus. 
  • Zinc acetate/carrageenan gels exhibit potent activity in vivo against high-dose herpes simplex virus 2 vaginal and rectal challenge. 
  • p38 signaling and receptor recycling events in a microfluidic endothelial cell adhesion assay. 
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  Keywords of People

  • Erickson, Harold Paul, James B. Duke Distinguished Professor Emeritus, Cell Biology
  • Katz, David F., Nello L. Teer, Jr. Distinguished Professor of Biomedical Engineering, in the Edmund T. Pratt, Jr. School of Engineering, Biomedical Engineering
  • Milano, Carmelo Alessio, Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery, Surgery, Cardiovascular and Thoracic Surgery
  • Starmer, Charles Franklin, Professor Emeritus of Computer Science, Computer Science
  • Wolpert, Robert L., Professor Emeritus of Statistical Science, Environmental Sciences and Policy