Ribosomes

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  Subject Areas on Research

  • 5' UTR m(6)A Promotes Cap-Independent Translation. 
  • 5'-Terminal nucleotide sequence of Escherichia coli lactose repressor mRNA: features of translational initiation and reinitiation sites. 
  • A novel ensemble-based scoring and search algorithm for protein redesign and its application to modify the substrate specificity of the gramicidin synthetase a phenylalanine adenylation enzyme. 
  • A novel interface for variable flow nanoscale LC/MS/MS for improved proteome coverage. 
  • A platform for compartmentalized protein synthesis: protein translation and translocation in the ER. 
  • A predicted secondary structural domain within the internal ribosome entry site of echovirus 12 mediates a cell-type-specific block to viral replication. 
  • A ribosome binding site from the pR RNA of bacteriophage lambda. 
  • Accurate multiplex gene synthesis from programmable DNA microchips. 
  • Activity of a type 1 picornavirus internal ribosomal entry site is determined by sequences within the 3' nontranslated region. 
  • An ARF-independent c-MYC-activated tumor suppression pathway mediated by ribosomal protein-Mdm2 Interaction. 
  • An electron microscopic study of pigeon aorta cell cultures. Cytodifferentiation and intracellular lipid accumulation. 
  • Analysis of mRNA partitioning between the cytosol and endoplasmic reticulum compartments of mammalian cells. 
  • Assessment of sex steroid action in vitro. 
  • Atomic force microscopy captures folded ribosome bound nascent chains. 
  • Attenuation of herpes simplex virus neurovirulence with picornavirus cis-acting genetic elements. 
  • Bacteriophage lambda N gene leader RNA. RNA processing and translational initiation signals. 
  • Biochemical fractionation and assembly of the membrane components that mediate nascent chain targeting and translocation. 
  • Bovine mitochondrial initiation and elongation factors. 
  • Cell-type-specific repression of internal ribosome entry site activity by double-stranded RNA-binding protein 76. 
  • Comparison of the Euglena chloroplast protein synthesizing system with those of prokaryotes and eukaryotes. 
  • Competitive translation efficiency at the picornavirus type 1 internal ribosome entry site facilitated by viral cis and trans factors. 
  • Concerning the mechanism of FSH action: rapid stimulation of testicular synthesis of nuclear RNA. 
  • Covariation of branch lengths in phylogenies of functionally related genes. 
  • De novo translation initiation on membrane-bound ribosomes as a mechanism for localization of cytosolic protein mRNAs to the endoplasmic reticulum. 
  • Direct ribosomal binding by a cellular inhibitor of translation. 
  • Discovery and fine mapping of serum protein loci through transethnic meta-analysis. 
  • Distinctive patterns of translational reinitiation in the lac repressor mRNA: bridging of long distances by out-of-frame translation and RNA secondary structure, effects of primary sequence. 
  • Divergent regulation of protein synthesis in the cytosol and endoplasmic reticulum compartments of mammalian cells. 
  • Effect of chemical modification of dihydrouridine in yeast transfer ribonucleic acid on amino acid acceptor activity and ribosomal binding. 
  • Effect of cyclic adenosine 3',5'-monophosphate on the incorporation of 3H-leucine into polypeptides by beef thyroid polysomes in vitro. 
  • Effects of Escherichia coli physiology on growth of phage T7 in vivo and in silico. 
  • Effects of length and mRNA secondary structure on the interaction of bovine mitochondrial ribosomes with messenger RNA. 
  • Electron microscopy of young Candida albicans chlamydospores. 
  • Endoplasmic reticulum-bound ribosomes reside in stable association with the translocon following termination of protein synthesis. 
  • Estrogen-induced changes in translation, and specific messenger RNA levels during oviduct differentiation. 
  • Euglena gracilis chloroplast small subunit rRNA. Sequence and base pairing potential of the 3' terminus, cleavage by colicin E3. 
  • Exploiting the complementary nature of LC/MALDI/MS/MS and LC/ESI/MS/MS for increased proteome coverage. 
  • Expression of rRNA and tRNA genes in Escherichia coli: evidence for feedback regulation by products of rRNA operons. 
  • Flipping of the ribosomal A-site adenines provides a basis for tRNA selection. 
  • Functional analysis of lac repressor restart sites in translational initiation and reinitiation. 
  • Gene expression throughout a vertebrate's embryogenesis. 
  • Genetically stable picornavirus expression vectors with recombinant internal ribosomal entry sites. 
  • Global translational reprogramming is a fundamental layer of immune regulation in plants. 
  • Grc3 programs the essential endoribonuclease Las1 for specific RNA cleavage. 
  • Hierarchical regulation of mRNA partitioning between the cytoplasm and the endoplasmic reticulum of mammalian cells. 
  • Hormonal control of oviduct growth and differentiation. 
  • Human La antigen is required for the hepatitis C virus internal ribosome entry site-mediated translation. 
  • Identification and initial characterization of translational initiation factor 2 from bovine mitochondria. 
  • Identification of a novel stage of ribosome/nascent chain association with the endoplasmic reticulum membrane. 
  • Improved computer program data for the resolution and fractionation of macromolecules by isokinetic sucrose density gradient sedimentation. 
  • In vitro and tissue culture methods for analysis of translation initiation on the endoplasmic reticulum. 
  • In-frame overlapping genes: the challenges for regulating gene expression. 
  • Induction of specific translatable messenger RNA's by oestrogen and progesterone. 
  • Influence of dimethylsulfoxide on RNA structure and ligand binding. 
  • Initiation of protein synthesis in animal mitochondria. Purification and characterization of translational initiation factor 2. 
  • Interaction of bovine mitochondrial ribosomes with messenger RNA. 
  • Interactions of bovine mitochondrial phenylalanyl-tRNA with ribosomes and elongation factors from mitochondria and bacteria. 
  • Internal ribosomal entry site substitution eliminates neurovirulence in intergeneric poliovirus recombinants. 
  • Isolation of polyribosomes and characteristics of an amino acid-incorporation system from the liver of a primate (Papio papio). 
  • Isolation of protein factors from oviduct polysomes which stimulate protein synthesis. 
  • LOCAL TRANSLATION. Comment on "Principles of ER cotranslational translocation revealed by proximity-specific ribosome profiling". 
  • Membranomyces species are common ectomycorrhizal symbionts in Northern Hemisphere forests. 
  • Messenger RNA conformation and ribosome selection of translational reinitiation sites in the lac repressor mRNA. 
  • Methods to Investigate the Regulatory Role of Small RNAs and Ribosomal Occupancy of Plasmodium falciparum. 
  • Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome. 
  • Molecular genetics of yeast. 
  • Multifunctional roles for the protein translocation machinery in RNA anchoring to the endoplasmic reticulum. 
  • Nascent secretory chain binding and translocation are distinct processes: differentiation by chemical alkylation. 
  • Nitric oxide-dependent ribosomal RNA cleavage is associated with inhibition of ribosomal peptidyl transferase activity in ANA-1 murine macrophages. 
  • Novel stress-responsive genes EMG1 and NOP14 encode conserved, interacting proteins required for 40S ribosome biogenesis. 
  • Observation of dually decoded regions of the human genome using ribosome profiling data. 
  • Ovalbumin messenger RNA of chick oviduct: partial characterization, estrogen dependence, and translation in vitro. 
  • Partitioning and translation of mRNAs encoding soluble proteins on membrane-bound ribosomes. 
  • Pathways for compartmentalizing protein synthesis in eukaryotic cells: the template-partitioning model. 
  • Peptidyl transferase centres of rat and yeast ribosomes. Different response to modification of protein amino groups. 
  • Poly(A)-binding protein is differentially required for translation mediated by viral internal ribosome entry sites. 
  • Preparation and preliminary characterization of purified ovalbumin messenger RNA from the hen oviduct. 
  • Primary role for endoplasmic reticulum-bound ribosomes in cellular translation identified by ribosome profiling. 
  • Protein biosynthesis in the testis. V. Concerning the mechanism of stimulation by follicle-stimulating hormone. 
  • Protein biosynthesis on chick oviduct polyribosomes. I. Changes during estrogen-mediated tissue differentiation. 
  • Protein biosynthesis on chick oviduct polyribosomes. II. Regulation by progesterone. 
  • Protein bisoynthesis in the testis. IV. Isolation and properties of polyribosomes. 
  • Protein synthesis, microsomes, and polyribosomes in oral tissues. 
  • Purification and activity study of the A- and B-chains of cinnamomin, a type II ribosome-inactivating protein. 
  • Purification of alpha-sarcin and an antifungal protein from Aspergillus giganteus by blue sepharose CL-6B affinity chromatography. 
  • Reconstitution of rat liver 60S ribosomal subunits following disassembly by dimethylmaleic anhydride. 
  • Regulation of ribosome detachment from the mammalian endoplasmic reticulum membrane. 
  • Regulation of the ribosome-membrane junction at early stages of presecretory protein translocation in the mammalian endoplasmic reticulum. 
  • Regulation of translation and transcription of messenger RNA during early embryonic development. 
  • Relation of neuronal endoplasmic reticulum calcium homeostasis to ribosomal aggregation and protein synthesis: implications for stress-induced suppression of protein synthesis. 
  • Response of bone marrow to MC29 avian leukosis virus in vitro. 
  • Revising messages traveling along the cellular information superhighway. 
  • Ribonomic analysis of human Pum1 reveals cis-trans conservation across species despite evolution of diverse mRNA target sets. 
  • Ribosomal RACK1:Protein Kinase C βII Modulates Intramolecular Interactions between Unstructured Regions of Eukaryotic Initiation Factor 4G (eIF4G) That Control eIF4E and eIF3 Binding. 
  • Ribosomal RACK1:Protein Kinase C βII Phosphorylates Eukaryotic Initiation Factor 4G1 at S1093 To Modulate Cap-Dependent and -Independent Translation Initiation. 
  • Ribosomal RNA in avian leukosis virus particles. 
  • Ribosomal subunits of Landschütz ascites cells during changes in polysome distribution. 
  • Ribosome exchange revisited: a mechanism for translation-coupled ribosome detachment from the ER membrane. 
  • Ribosome-independent regulation of translocon composition and Sec61alpha conformation. 
  • Role of arginine 180 and glutamic acid 177 of ricin toxin A chain in enzymatic inactivation of ribosomes. 
  • Sequential changes in bulk renal protein and polyribosomes in the acutely obstructed mouse kidney. 
  • Simple and inexpensive ribosome profiling analysis of mRNA translation. 
  • Small but Mighty: Functional Peptides Encoded by Small ORFs in Plants. 
  • Stable ribosome binding to the endoplasmic reticulum enables compartment-specific regulation of mRNA translation. 
  • Stage- and ribosome-specific alterations in nascent chain-Sec61p interactions accompany translocation across the ER membrane. 
  • Steroid hormone induction of a specific translatable messenger RNA. 
  • Steroid hormone regulation of specific messenger RNA and protein synthesis in eucaryotic cells. 
  • Stimulation of cell-free polypeptide synthesis by a protein fraction extracted from chick oviduct polyribosomes. 
  • Stimulation of synthesis of ribonucleic acid in sub-apical sections of Avena coleoptile by indolyl-3-acetic acid. 
  • Structural determinants of insert retention of poliovirus expression vectors with recombinant IRES elements. 
  • Temporal dynamics of Wnt-dependent transcriptome reveal an oncogenic Wnt/MYC/ribosome axis. 
  • The DRiP hypothesis decennial: support, controversy, refinement and extension. 
  • The effect of protein synthesis inhibition on the entry of messenger RNA into the cytoplasm of sea urchin embryos. 
  • The enduring enigma of nuclear translation. 
  • The fate of membrane-bound ribosomes following the termination of protein synthesis. 
  • The inoculum effect and band-pass bacterial response to periodic antibiotic treatment. 
  • The large subunit of the mammalian mitochondrial ribosome. Analysis of the complement of ribosomal proteins present. 
  • The role of ribosomal subunits and 80-S monomers in polysome formation in an ascites tumour cell. 
  • The signal sequence receptor, unlike the signal recognition particle receptor, is not essential for protein translocation. 
  • The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present. 
  • Transcriptomic profiles of aging in purified human immune cells. 
  • Translation at higher than an optimal level interferes with coupling at an intercistronic junction. 
  • Translation limits synthesis of an assembly-initiating coat protein of filamentous phage IKe. 
  • Translational control of phage f1 gene expression by differential activities of the gene V, VII, IX and VIII initiation sites. 
  • Visualizing transient low-populated structures of RNA. 
  • he effect of inhibitors of protein synthesis on the level of ribosomal subunits in ascites cells. 
  • mRNA translation is compartmentalized to the endoplasmic reticulum following physiological inhibition of cap-dependent translation.