RNA

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  Subject Areas on Research

  • 2'Fluoro Modification Differentially Modulates the Ability of RNAs to Activate Pattern Recognition Receptors. 
  • 3D maps of RNA interhelical junctions. 
  • A Common Variant in MIR182 Is Associated With Primary Open-Angle Glaucoma in the NEIGHBORHOOD Consortium. 
  • A Comparative Study of Serum Exosome Isolation Using Differential Ultracentrifugation and Three Commercial Reagents. 
  • A DNA-binding-independent pathway of repression by the Drosophila Runt protein. 
  • A Xenopus egg factor with DNA-binding properties characteristic of terminus-specific telomeric proteins. 
  • A case study of the reproducibility of transcriptional reporter cell-based RNAi screens in Drosophila. 
  • A circular trans-acting hepatitis delta virus ribozyme. 
  • A common RNA recognition motif identified within a defined U1 RNA binding domain of the 70K U1 snRNP protein. 
  • A comparative analysis of the information content in long and short SAGE libraries. 
  • A comparison of methods for RNA extraction from lymphocytes for RT-PCR. 
  • A copper-regulated transporter required for copper acquisition, pigmentation, and specific stages of development in Drosophila melanogaster. 
  • A different life? 
  • A functional isoform of the human granulocyte/macrophage colony-stimulating factor receptor has an unusual cytoplasmic domain. 
  • A genetically tractable model of human glioma formation. 
  • A high-resolution map of human evolutionary constraint using 29 mammals. 
  • A light-inducible CRISPR-Cas9 system for control of endogenous gene activation. 
  • A major role for the EP4 receptor in regulation of renin. 
  • A method for analysis of gene expression patterns. 
  • A missense mutation in exon 4 of the human adenosine deaminase gene causes severe combined immunodeficiency. 
  • A mutation in the largest subunit of RNA polymerase II alters RNA chain elongation in vitro. 
  • A negative coregulator for the human ER. 
  • A novel multi-tissue RNA diagnostic of healthy ageing relates to cognitive health status. 
  • A novel process for optimizing musculoskeletal allograft tissue to improve safety, ultrastructural properties, and cell infiltration. 
  • A novel species-specific RNA related to alternatively spliced amyloid precursor protein mRNAs. 
  • A nuclear role for the Fragile X mental retardation protein. 
  • A paired-end sequencing strategy to map the complex landscape of transcription initiation. 
  • A research for the relationship between human papillomavirus and human uterine cervical carcinoma. II. Molecular genetic and ultrastructural study on the transforming activity of recombinant retrovirus containing human papillomavirus type 16 subgenomic sequences. 
  • A role for nuclear factor kappa B/rel transcription factors in the regulation of the recombinase activator genes. 
  • A small circular TAR RNA decoy specifically inhibits Tat-activated HIV-1 transcription. 
  • A statistical and biological response to an informatics appraisal of healthy aging gene signatures. 
  • A versatile microporation technique for the transfection of cultured CNS neurons. 
  • Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity. 
  • Abnormal gene expression profiles in unaffected parents of patients with hereditary-type retinoblastoma. 
  • Accumulation of hedgehog-responsive progenitors parallels alcoholic liver disease severity in mice and humans. 
  • Activation of MEF2 by muscle activity is mediated through a calcineurin-dependent pathway. 
  • Activation of the heat shock transcription factor by hypoxia in mammalian cells. 
  • Activity of a type 1 picornavirus internal ribosomal entry site is determined by sequences within the 3' nontranslated region. 
  • Acute tubular necrosis. An experimental model detailing the biochemical events accompanying renal injury and recovery. 
  • Acute vascular rejection and accommodation: divergent outcomes of the humoral response to organ transplantation. 
  • Adenovirus 12S E1A gene represses differentiation of F9 teratocarcinoma cells. 
  • Advances in the determination of nucleic acid conformational ensembles. 
  • Advances, interactions, and future developments in the CNS, Phenix, and Rosetta structural biology software systems. 
  • Altered gene expression and DNA damage in peripheral blood cells from Friedreich's ataxia patients: cellular model of pathology. 
  • Alternative processing of androgen-binding protein RNA transcripts in fetal rat liver. Identification of a transcript formed by trans splicing. 
  • Alternative splicing in disease and therapy. 
  • An Arabidopsis thaliana lipoxygenase gene can be induced by pathogens, abscisic acid, and methyl jasmonate. 
  • An ectopic human XIST gene can induce chromosome inactivation in postdifferentiation human HT-1080 cells. 
  • Analysis of expression of multiple genes encoding calmodulin during spermatogenesis. 
  • Animals lacking endothelin-converting enzyme-2 are deficient in learning and memory. 
  • Antigen receptor control of methionine metabolism in T cells. 
  • Antimetastatic potential of PAI-1-specific RNA aptamers. 
  • Approximate reconstruction of continuous spatially complex domain motions by multialignment NMR residual dipolar couplings. 
  • Aptamers in immunotherapy. 
  • Aspirin exposure reveals novel genes associated with platelet function and cardiovascular events. 
  • Association between the 7 S RNA and the lupus La protein varies among cell types. 
  • Association of the viral reverse transcriptase with an enzyme degrading the RNA moiety of RNA-DNA hybrids. 
  • Attenuated hepatic inflammation and fibrosis in angiotensin type 1a receptor deficient mice. 
  • Aurora Kinase A is critical for the Nkx6.1 mediated β-cell proliferation pathway. 
  • Bacterial lipopolysaccharide induces uncoupling protein-2 expression in hepatocytes by a tumor necrosis factor-alpha-dependent mechanism. 
  • Bacteriophage T4 helicase loader protein gp59 functions as gatekeeper in origin-dependent replication in vivo. 
  • Balloon catheterization induced arterial expression of embryonic fibronectins. 
  • BayFish: Bayesian inference of transcription dynamics from population snapshots of single-molecule RNA FISH in single cells. 
  • Beta adrenergic control of macromolecule synthesis in neonatal rat heart, kidney and lung: relationship to sympathetic neuronal development. 
  • Beta-adrenergic control of c-fos expression in fetal and neonatal rat tissues: relationship to cell differentiation and teratogenesis. 
  • Beta-catenin mediates soft tissue contracture in clubfoot. 
  • Beyond static structures of RNA by NMR: folding, refolding, and dynamics at atomic resolution. 
  • Binding sites of the 9- and 14-kilodalton heterodimeric protein subunit of the signal recognition particle (SRP) are contained exclusively in the Alu domain of SRP RNA and contain a sequence motif that is conserved in evolution. 
  • Biochemical determinants of growth sparing during neonatal nutritional deprivation or enhancement: ornithine decarboxylase, polyamines, and macromolecules in brain regions and heart. 
  • Biochemical development of the rat lung: studies on cellular DNA, RNA and protein content in relation to maternal vitamin A status. 
  • Blocking the initiation of coagulation by RNA aptamers to factor VIIa. 
  • Blood-sample processing for the study of age-dependent gene expression in peripheral blood mononuclear cells. 
  • Bone marrow biopsy: RNA isolation with expression profiling in men with metastatic castration-resistant prostate cancer--factors affecting diagnostic success. 
  • Bone morphogenetic protein-4 (BMP-4) acts during gastrula stages to cause ventralization of Xenopus embryos. 
  • Bone morphogenetic proteins are expressed by both bone-forming and non-bone-forming lesions. 
  • Brain-specific polyA- transcripts are detected in polyA+ RNA: do complex polyA- brain RNAs really exist? 
  • Calmodulin is required for cell-cycle progression during G1 and mitosis. 
  • Carbon monoxide, skeletal muscle oxidative stress, and mitochondrial biogenesis in humans. 
  • Catecholaminergic cell lines from the brain and adrenal glands of tyrosine hydroxylase-SV40 T antigen transgenic mice. 
  • Cellular and molecular mechanisms of pomegranate juice-induced anti-metastatic effect on prostate cancer cells. 
  • Characteristics of the interaction of a synthetic human tristetraprolin tandem zinc finger peptide with AU-rich element-containing RNA substrates. 
  • Characterization of 67 kD laminin receptor, a protein whose gene is overexpressed on treatment of cells with anti-benzo[a]pyrene-7,8-diol-9,10-epoxide. 
  • Characterization of cDNA encoding mouse DNA repair protein O6-methylguanine-DNA methyltransferase and high-level expression of the wild-type and mutant proteins in Escherichia coli. 
  • Characterization of interactions between PinX1 and human telomerase subunits hTERT and hTR. 
  • Characterization of the hyperpolarization-activated chloride current in dissociated rat sympathetic neurons. 
  • Characterizing RNA dynamics at atomic resolution using solution-state NMR spectroscopy. 
  • Characterizing the relative orientation and dynamics of RNA A-form helices using NMR residual dipolar couplings. 
  • Charge-reversal lipids, peptide-based lipids, and nucleoside-based lipids for gene delivery. 
  • Chemical evidence for early but unsustained growth in the obstructed mouse kidney. 
  • Chemical structure of carbamoylating groups and their relationship to bone marrow toxicity and antiglioma activity of bifunctionally alkylating and carbamoylating nitrosoureas. 
  • Chondrocyte transport and concentration of ascorbic acid is mediated by SVCT2. 
  • Chromosomal translocation in a human leukemic stem-cell line disrupts the T-cell antigen receptor delta-chain diversity region and results in a previously unreported fusion transcript. 
  • CircIRAK3 sponges miR-3607 to facilitate breast cancer metastasis. 
  • Circular RNAs are abundant, conserved, and associated with ALU repeats. 
  • Circular transcripts of the testis-determining gene Sry in adult mouse testis. 
  • Circularizing ribozymes and decoy-competitors by autocatalytic splicing in vitro and in vivo. 
  • Cloning and characterization of developmental endothelial locus-1: an embryonic endothelial cell protein that binds the alphavbeta3 integrin receptor. 
  • Cloning and characterization of three new murine genes encoding short homologues of RNase P RNA. 
  • Cloning of DNA corresponding to rare transcripts of rat brain: evidence of transcriptional and post-transcriptional control and of the existence of nonpolyadenylated transcripts. 
  • Coarse grained models reveal essential contributions of topological constraints to the conformational free energy of RNA bulges. 
  • Comparative analysis of the HTLV-I Rex and HIV-1 Rev trans-regulatory proteins and their RNA response elements. 
  • Comparing reference-based RNA-Seq mapping methods for non-human primate data. 
  • Compensatory renal growth after unilateral ureteral obstruction. 
  • Complement-Mediated Regulation of Apolipoprotein E in Cultured Human RPE Cells. 
  • Complementary techniques: RNA amplification for gene profiling analysis. 
  • Complexity of cytoplasmic polyadenylated and nonpolyadenylated rat brain ribonucleic acids. 
  • Composition and dynamics of the Caenorhabditis elegans early embryonic transcriptome. 
  • Comprehensive analysis of the chromatin landscape in Drosophila melanogaster. 
  • Computational Methods for RNA Structure Validation and Improvement. 
  • Computing. Successes and challenges. 
  • Concerning the mechanism of FSH action: rapid stimulation of testicular synthesis of nuclear RNA. 
  • Conditional telomerase induction causes proliferation of hair follicle stem cells. 
  • Constructing atomic-resolution RNA structural ensembles using MD and motionally decoupled NMR RDCs. 
  • Control of nucleic acid and protein synthesis in developing brain, kidney, and heart of the neonatal rat: effects of alpha-difluoromethylornithine, a specific, irreversible inhibitor of ornithine decarboxylase. 
  • Control of phenylalanine hydroxylase synthesis in tissue culture by serum and insulin. 
  • Coordinate reduction of rat pancreatic islet glucokinase and proinsulin mRNA by exercise training. 
  • Cotransfection of DC with TLR4 and MART-1 RNA induces MART-1-specific responses. 
  • Creation of human tumour cells with defined genetic elements. 
  • Crosstalk in competing endogenous RNA networks reveals new circular RNAs involved in the pathogenesis of early HIV infection. 
  • Crystal structure of a pol alpha family DNA polymerase from the hyperthermophilic archaeon Thermococcus sp. 9 degrees N-7. 
  • Cti6 is an Rpd3-Sin3 histone deacetylase-associated protein required for growth under iron-limiting conditions in Saccharomyces cerevisiae. 
  • Cytological evidence of transcription of highly repeated DNA sequences during the lampbrush stage in Triturus cristatus carnifex. 
  • DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration. 
  • DNA methyltransferase 3B mutations linked to the ICF syndrome cause dysregulation of lymphogenesis genes. 
  • DO-RIP-seq to quantify RNA binding sites transcriptome-wide. 
  • Deciphering the molecular machinery of stem cells: a look at the neoblast gene expression profile. 
  • Defective cellular immunity associated with chronic mucocutaneous moniliasis and recurrent staphylococcal botryomycosis: immunological reconstitution by allogeneic bone marrow. 
  • Dendritic cells engineered to secrete anti-GITR antibodies are effective adjuvants to dendritic cell-based immunotherapy. 
  • Dendritic cells pulsed with RNA are potent antigen-presenting cells in vitro and in vivo. 
  • Detecting and characterizing circular RNAs. 
  • Detection of differentially regulated genes in ischaemic equine intestinal mucosa. 
  • Developmental neurotoxicity of chlorpyrifos: delayed targeting of DNA synthesis after repeated administration. 
  • Developmental pattern of the hepatic DNA, RNA and protein in relation to maternal vitamin A status in rats. 
  • Developmental regulation of calmodulin, actin, and tubulin RNAs during rat testis differentiation. 
  • Diagnostic potential of prostate-specific antigen expressing epithelial cells in blood of prostate cancer patients. 
  • Dietary regulation of rat intestinal cholecystokinin gene expression. 
  • Difference between mitochondrial RNase P and nuclear RNase P. 
  • Differential Induction of Immunogenic Cell Death and Interferon Expression in Cancer Cells by Structured ssRNAs. 
  • Differential expression of genes encoding TGFs beta 1, beta 2, and beta 3 during murine palate formation. 
  • Differential expression of the homeobox gene Hox-1.3 in F9 embryonal carcinoma cells. 
  • Differential gene expression of blood-derived cell lines in familial combined hyperlipidemia. 
  • Differential requirements for segment polarity genes in wingless signaling. 
  • Differential responsiveness of MCF-7 human breast cancer cell line stocks to the pineal hormone, melatonin. 
  • Differential systemic gene expression profile in patients with diabetic macular edema: responders versus nonresponders to standard treatment. 
  • Differentiating pancreatic lesions by microarray and QPCR analysis of pancreatic juice RNAs. 
  • Differentiation and classification of RNA motifs using small molecule-based pattern recognition. 
  • Digital image analysis for rapid quantification of total RNA and cDNA for SMART-PCR. 
  • Direct NMR Evidence that Transient Tautomeric and Anionic States in dG·dT Form Watson-Crick-like Base Pairs. 
  • Direct assessment of articular cartilage and underlying subchondral bone reveals a progressive gene expression change in human osteoarthritic knees. 
  • Direct fluorescence detection of RNA on microarrays by surface-initiated enzymatic polymerization. 
  • Discovery of Key Physicochemical, Structural, and Spatial Properties of RNA-Targeted Bioactive Ligands. 
  • Discovery of Small Molecule Ligands for MALAT1 by Tuning an RNA-Binding Scaffold. 
  • Discovery of selective bioactive small molecules by targeting an RNA dynamic ensemble. 
  • Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization. 
  • Distinctive RNA expression profiles in blood associated with white matter hyperintensities in brain. 
  • Do sympathetic neurons coordinate cellular development in the heart and kidney? Effects of neonatal central and peripheral catecholaminergic lesions on cardiac and renal nucleic acids and proteins. 
  • Doing molecular biophysics: finding, naming, and picturing signal within complexity. 
  • Downregulation of TSLC1 and DAL-1 expression occurs frequently in breast cancer. 
  • Dynamics of large elongated RNA by NMR carbon relaxation. 
  • Dynamics-based amplification of RNA function and its characterization by using NMR spectroscopy. 
  • Early activation and cell cycle entry of resting B cells after Fab-anti-Ig treatment: role of receptor crosslinking. 
  • Early biochemical detection of delayed neurotoxicity resulting from developmental exposure to chloropyrifos. 
  • Early estrogen action: concomitant stimulations within two minutes of nuclear RNA synthesis and uptake of RNA precursor by the uterus. 
  • Early estrogen action: nuclear synthesis and accumulation of protein correlated with enhancement of two DNA-dependent RNA polymerase activities. 
  • Early history of circular RNAs, children of splicing. 
  • Effect of RNA secondary structure on polyadenylation site selection. 
  • Effect of transient hydronephrosis on subsequent compensatory renal growth. 
  • Effective treatment of models of multiple sclerosis by matrix metalloproteinase inhibitors. 
  • Effects of alpha-difluoromethylornithine, a specific irreversible inhibitor of ornithine decarboxylase, on nucleic acids and proteins in developing rat brain: critical perinatal periods for regional selectivity. 
  • Effects of magnesium ions on the stabilization of RNA oligomers of defined structures. 
  • Effects of neonatal methylmercury exposure on development of nucleic acids and proteins in rat brain: regional specificity. 
  • Effects of prenatal nicotine exposure on biochemical development of rat brain regions: maternal drug infusions via osmotic minipumps. 
  • Effects of prenatal terbutaline exposure on cellular development in lung and liver of neonatal rat: ornithine decarboxylase activity and macromolecules. 
  • Effects of vitamin A and phenobarbital on liver endoplasmic reticulum of rats. 
  • Efficient and specific repair of sickle beta-globin RNA by trans-splicing ribozymes. 
  • Efficient processing of primary microRNA hairpins by Drosha requires flanking nonstructured RNA sequences. 
  • Electron transfer characteristics of 2'-deoxy-2'-fluoro-arabinonucleic acid, a nucleic acid with enhanced chemical stability. 
  • Elongation by Drosophila RNA polymerase II. Transcription of 3'-extended DNA templates. 
  • Elucidating the molecular mechanism of cardiac remodeling using a comparative genomic approach. 
  • Embryonic expression of a haematopoietic growth factor encoded by the Sl locus and the ligand for c-kit. 
  • Emerging clinical applications of RNA. 
  • Encoded multichromophore response for simultaneous label-free detection. 
  • Endoglin gene polymorphism as a risk factor for sporadic intracerebral hemorrhage. 
  • Endotoxin-stimulated nitric oxide production inhibits expression of cytochrome c oxidase in ANA-1 murine macrophages. 
  • Engineered Ribonucleoprotein Granules Inhibit Translation in Protocells. 
  • Enhanced growth of small bowel in transgenic mice overexpressing bovine growth hormone. 
  • Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells. 
  • Enhancing RNA repair efficiency by combining trans-splicing ribozymes that recognize different accessible sites on a target RNA. 
  • Epstein-Barr virus latent infection membrane protein 1 TRAF-binding site induces NIK/IKK alpha-dependent noncanonical NF-kappaB activation. 
  • Essential amino acid deprivation induces monocytic differentiation of the human HL-60 myeloid leukemia cell line. 
  • Estrogen-induced synthesis of ovalbumin messenger RNA and its translation in a cell-free system. 
  • Evaluating and enhancing ribozyme reaction efficiency in mammalian cells. 
  • Evaluating the specificity of antisense oligonucleotide conjugates. A DNA array analysis. 
  • Evaluating whole transcriptome amplification for gene profiling experiments using RNA-Seq. 
  • Evidence for depression of nuclear protein synthesis and concomitant stimulation of nuclear RNA synthesis during early estrogen action. 
  • Evidence that electrostatic interactions dictate the ligand-induced arrest of RNA global flexibility. 
  • Excitatory amino acid receptor activation produces a selective and long-lasting modulation of gene expression in hippocampal neurons. 
  • Exon circularization in mammalian nuclear extracts. 
  • Expanding the CRISPR Toolbox: Targeting RNA with Cas13b. 
  • Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. 
  • Expression and sequence analysis of a cDNA encoding the orotidine-5'-monophosphate decarboxylase domain from Ehrlich ascites uridylate synthase. 
  • Expression and subcellular distribution of mouse cytochrome P1-450 mRNA as determined by molecular hybridization with cloned P1-450 DNA. 
  • Expression microarray identifies novel markers of free flap failure in a rat model. 
  • Expression of CD44 and variant isoforms in cultured human retinal pigment epithelial cells. 
  • Expression of TERT in early premalignant lesions and a subset of cells in normal tissues. 
  • Expression of a chemokine by ciliary body epithelium in horses with naturally occurring recurrent uveitis and in cultured ciliary body epithelial cells. 
  • Expression of a constitutive form of calcium/calmodulin dependent protein kinase II leads to arrest of the cell cycle in G2. 
  • Expression of aquaporin-1 in human trabecular meshwork cells: role in resting cell volume. 
  • Expression of c-fos in parietal endoderm, amnion and differentiating F9 teratocarcinoma cells. 
  • Expression of five selected human mismatch repair genes simultaneously detected in normal and cancer cell lines by a nonradioactive multiplex reverse transcription-polymerase chain reaction. 
  • Expression of non-N-methyl-D-aspartate glutamate receptor subunits in the olfactory epithelium. 
  • Expression of photosynthesis genes in relation to nitrogen fixation in the diazotrophic filamentous nonheterocystous cyanobacterium Trichodesmium sp. IMS 101. 
  • Expression of transforming growth factor beta 2 RNA during murine embryogenesis. 
  • Expression, purification, and identification of associated proteins of the full-length hCDK12/CyclinK complex. 
  • Extending the NMR spatial resolution limit for RNA by motional couplings. 
  • Extraction and comparison of gene expression patterns from 2D RNA in situ hybridization images. 
  • Failure of adrenal corticosterone production in POMC-deficient mice results from lack of integrated effects of POMC peptides on multiple factors. 
  • Female steroid hormones and target cell nuclei. 
  • Fluorescent peptide displacement as a general assay for screening small molecule libraries against RNA. 
  • Forced expression of AID facilitates the isolation of class switch variants from hybridoma cells. 
  • Functional complexity and regulation through RNA dynamics. 
  • G-quadruplex structures trigger RNA phase separation. 
  • GSAASeqSP: a toolset for gene set association analysis of RNA-Seq data. 
  • GYGD pore motifs in neighbouring potassium channel subunits interact to determine ion selectivity. 
  • Gating currents from a delayed rectifier K+ channel with altered pore structure and function. 
  • Gene Expression Profiling in the Hibernating Primate, Cheirogaleus Medius. 
  • Gene expression in obliterative bronchiolitis-like lesions in 2,3-pentanedione-exposed rats. 
  • Gene expression in the rectus abdominus muscle of patients with and without pelvic organ prolapse. 
  • Gene expression profile in human trabecular meshwork from patients with primary open-angle glaucoma. 
  • Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain. 
  • Generating RNA Baits for Capture-Based Enrichment. 
  • Generation and characterization of circular Bacillus subtilis RNase P RNA; activation by RNase P protein. 
  • Generation of nuclease resistant circular RNA decoys for HIV-Tat and HIV-Rev by autocatalytic splicing. 
  • Generation of nuclease resistant circular RNA decoys for HIV-Tat and HIV-Rev by autocatalytic splicing. 
  • Generation of species cross-reactive aptamers using "toggle" SELEX. 
  • Genetic background influences cardiac phenotype in murine chronic kidney disease. 
  • Genetic basis of murine responses to hyperoxia-induced lung injury. 
  • Genome-wide high-resolution mapping of exosome substrates reveals hidden features in the Arabidopsis transcriptome. 
  • Genome-wide patterns of expression in Drosophila pure species and hybrid males. 
  • Genomic convergence: identifying candidate genes for Parkinson's disease by combining serial analysis of gene expression and genetic linkage. 
  • Genomic structure and chromosomal localization of the novel ETS factor, PE-2 (ERF). 
  • Genomics-Inspired Biomarkers and Diagnostics-Where Are They? 
  • Global analysis of gene expression in renal ischemia-reperfusion in the mouse. 
  • Global gene expression profiling of end-stage dilated cardiomyopathy using a human cardiovascular-based cDNA microarray. 
  • Group I permuted intron-exon (PIE) sequences self-splice to produce circular exons. 
  • Growth Differentiation Factor-15-Induced Contractile Activity and Extracellular Matrix Production in Human Trabecular Meshwork Cells. 
  • HEART DISEASE. Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy. 
  • HIV-1 Rev promotes the nuclear export of unspliced and singly spliced RNAs in a mammalian cell-free export system. 
  • HIV-1 leader RNA dimeric interface revealed by NMR. 
  • HL-A antigenic loss in malignant transformation. 
  • HMGB1 and microparticles as mediators of the immune response to cell death. 
  • Hedgehog signaling patterns mesoderm in the sea urchin. 
  • Hepatocyte nuclear factor 1 alpha is expressed in a hamster insulinoma line and transactivates the rat insulin I gene. 
  • Hepcidin, a candidate modifier of the hemochromatosis phenotype in mice. 
  • Hic-5 Regulates Actin Cytoskeletal Reorganization and Expression of Fibrogenic Markers and Myocilin in Trabecular Meshwork Cells. 
  • Hidden Structural Modules in a Cooperative RNA Folding Transition. 
  • Hierarchy of RNA functional dynamics. 
  • Human Schlemm's canal cells express the endothelial adherens proteins, VE-cadherin and PECAM-1. 
  • Human adipocyte lipid-binding protein: purification of the protein and cloning of its complementary DNA. 
  • Human dendritic cells transfected with RNA encoding prostate-specific antigen stimulate prostate-specific CTL responses in vitro. 
  • Human granulosa-luteal and cumulus cells express transforming growth factors-beta type 1 and type 2 mRNA. 
  • Human lymphocyte complement receptors. Stimulation of lymphocyte RNA synthesis by complement-coated human red cells. 
  • Human thymic epithelial cells produce IL-6, granulocyte-monocyte-CSF, and leukemia inhibitory factor. 
  • Human thymic epithelial cells produce granulocyte and macrophage colony-stimulating factors. 
  • Huntingtin is present in the nucleus, interacts with the transcriptional corepressor C-terminal binding protein, and represses transcription. 
  • Hybrid error correction and de novo assembly of single-molecule sequencing reads. 
  • Hybrid male sterility in Mimulus (Phrymaceae) is associated with a geographically restricted mitochondrial rearrangement. 
  • Hybridization studies with a renin cDNA probe: evidence for widespread expression of renin in the mouse. 
  • Hybridoma SLE autoantibodies: insights for the pathogenesis of autoimmune disease. 
  • Identification and characterization of a cDNA encoding cytochrome P450 3A from the fresh water teleost medaka (Oryzias latipes). 
  • Identification and characterization of a human homolog of the Schizosaccharomyces pombe ras-like gene YPT-3. 
  • Identification of Tat-SF1 cellular targets by exon array analysis reveals dual roles in transcription and splicing. 
  • Identification of an alternate promoter in the rat androgen-binding protein/sex hormone-binding globulin gene that regulates synthesis of a messenger RNA encoding a protein with altered function. 
  • Identification of genes expressed in a human scleral cDNA library. 
  • Identification of liver cancer-specific aptamers using whole live cells. 
  • Identification of mZnf8, a mouse Krüppel-like transcriptional repressor, as a novel nuclear interaction partner of Smad1. 
  • Identification of multiple species of calmodulin messenger RNA using a full length complementary DNA. 
  • Identification of rare-disease genes using blood transcriptome sequencing and large control cohorts. 
  • Identification of specific protein-RNA target sites using libraries of natural sequences. 
  • Identification of the RNA recognition element of the RBPMS family of RNA-binding proteins and their transcriptome-wide mRNA targets. 
  • Immune (gamma) interferon production by a murine T cell lymphoma: requirements for macromolecular synthesis and lack of relationship with cell cycle. 
  • Impact of exercise stress testing on diagnostic gene expression in patients with obstructive and nonobstructive coronary artery disease. 
  • Impact of the genetic background of transgenic mice upon the formation and timing of choroid plexus papillomas. 
  • Implementing a cumulative supermatrix approach for a comprehensive phylogenetic study of the Teloschistales (Pezizomycotina, Ascomycota). 
  • In situ hybridization analysis of TGF beta 3 RNA expression during mouse development: comparative studies with TGF beta 1 and beta 2. 
  • In vitro RNA selection identifies RNA ligands that specifically bind to eukaryotic translation initiation factor 4B: the role of the RNA remotif. 
  • In vitro chick embryo cell response to strain MC29 avian leukosis virus. 
  • In vitro selection of RNA epitopes using autoimmune patient serum. 
  • In vitro selection of an RNA epitope immunologically cross-reactive with a peptide. 
  • In vitro selection of aptamers from RNA libraries. 
  • In vitro synthesis of laminin and entactin polypeptides. 
  • In vitro synthesis of type IV procollagen. 
  • In vivo expression of mRNA for the Ca++-binding protein SPARC (osteonectin) revealed by in situ hybridization. 
  • In vivo selection of tumor-targeting RNA motifs. 
  • Incorporation of ribonucleoside 5'-(alpha-P-borano)triphosphates into a 20-mer RNA by T7 RNA polymerase. 
  • Increased expression of anti-apoptosis genes in peripheral blood cells from patients with paroxysmal nocturnal hemoglobinuria. 
  • Increased expression of the glucose-regulated gene encoding the Mr 78,000 glucose-regulated protein in chemically and radiation-transformed C3H 10T1/2 mouse embryo cells. 
  • Increasing the specificity of CRISPR systems with engineered RNA secondary structures. 
  • Inducing circular RNA formation using the CRISPR endoribonuclease Csy4. 
  • Induction of cytochrome P(1)450 RNA and benzo[a]pyrene metabolism in primary human hepatocyte cultures with benzanthracene. 
  • Induction of cytotoxic T cell responses and tumor immunity against unrelated tumors using telomerase reverse transcriptase RNA transfected dendritic cells. 
  • Induction of human dendritic cell maturation using transfection with RNA encoding a dominant positive toll-like receptor 4. 
  • Induction of immediate-early genes by angiotensin II and endothelin-1 in adult rat cardiomyocytes. 
  • Induction of primary carcinoembryonic antigen (CEA)-specific cytotoxic T lymphocytes in vitro using human dendritic cells transfected with RNA. 
  • Induction of uterine prostaglandin H synthase 2 by estradiol following fetal adrenalectomy. 
  • Induction therapy with monoclonal antibodies specific for CD80 and CD86 delays the onset of acute renal allograft rejection in non-human primates. 
  • Inflammatory biomarkers in osteoarthritis. 
  • Influence of dimethylsulfoxide on RNA structure and ligand binding. 
  • Inhibition of LPS toxicity for macrophages by metallothionein-inducing agents. 
  • Inhibition of cell proliferation by an RNA ligand that selectively blocks E2F function. 
  • Inhibition of nucleic acid methylation by cordycepin. In vivo synthesis of S-3'-DEOXYADENOSYLMETHIONINE BY WI-L2 human lymphoblasts. 
  • Inhibition of rat corneal angiogenesis by a nuclease-resistant RNA aptamer specific for angiopoietin-2. 
  • Initial sequencing and analysis of the human genome. 
  • Insight into the CSA tensors of nucleobase carbons in RNA polynucleotides from solution measurements of residual CSA: towards new long-range orientational constraints. 
  • Insights into domain-domain motions in proteins and RNA from solution NMR. 
  • Insights into the development of chemical probes for RNA. 
  • Interaction of RNA polymerase II with acetylated nucleosomal core particles. 
  • Interaction of RNA polymerase II with structurally altered nucleosomal particles. Transcription is facilitated by loss of one H2A.H2B dimer. 
  • Interaction with RNA polymerase of nucleosomal cores lacking one H2A.H2B dimer. 
  • Interactions of TLC1 (which encodes the RNA subunit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae. 
  • Interactions of plus and minus strand leader RNAs of the New Jersey serotype of vesicular stomatitis virus with the cellular La protein. 
  • Interferon action: effects of mouse alpha and beta interferons on rosette formation, phagocytosis, and surface-antigen expression of cells of the macrophage-type line RAW 309Cr.1. 
  • Investigating RNA expression profiles altered by nicotinamide mononucleotide therapy in a chronic model of alcoholic liver disease. 
  • Iron importers Zip8 and Zip14 are expressed in retina and regulated by retinal iron levels. 
  • Isolation and analysis of recombinant DNA molecules containing yeast DNA. 
  • Isolation and characterization of a new chemokine receptor gene, the putative chicken CXCR1. 
  • Isolation and characterization of the rat chromosomal gene for a polypeptide (pS1) antigenically related to statin. 
  • Isolation and expression of multiple forms of beta amyloid protein precursor cDNAs. 
  • Isolation and functional analysis of the mouse RXRgamma1 gene promoter in anterior pituitary cells. 
  • Isolation and localization of a slow troponin (TnT) gene on chromosome 19 by subtraction hybridization of a cDNA muscle library using myotonic dystrophy muscle cDNA. 
  • Isolation of a candidate cDNA for the gene causing retinal degeneration in the rd mouse. 
  • Isolation of a nuclease-resistant decoy RNA that can protect human acetylcholine receptors from myasthenic antibodies. 
  • Isolation of a nuclease-resistant decoy RNA that selectively blocks autoantibody binding to insulin receptors on human lymphocytes. 
  • Isolation of cDNA clones coding for the beta subunit of human beta-hexosaminidase. 
  • Isolation of microarray-quality RNA from primary human cells after intracellular immunostaining and fluorescence-activated cell sorting. 
  • Isolation of the structural gene for calmodulin. 
  • Isolation, characterization and chromosomal localization of cDNA clones for the E1 beta subunit of the pyruvate dehydrogenase complex. 
  • Kinetics of expression of multiply spliced RNA in early human immunodeficiency virus type 1 infection of lymphocytes and monocytes. 
  • Know thyself. 
  • Kupffer cell depletion by CI2MDP-liposomes alters hepatic cytokine expression and delays liver regeneration after partial hepatectomy. 
  • Laser-capture microdissection. 
  • Letter: Role of reverse transcriptase. 
  • Little qualitative RNA misexpression in sterile male F1 hybrids of Drosophila pseudoobscura and D. persimilis. 
  • Long-term protein and calorie restriction: alterations in nucleic acid levels of organs of male rats. 
  • Macromolecular levels, DNA synthesis and ornithine decarboxylase activity in leg muscles from 6-mercaptopurine-treated rats. 
  • Mapping Hfq-RNA interaction surfaces using tryptophan fluorescence quenching. 
  • Maternal vitamin A restriction alters biochemical development of the brain in rats. 
  • Maturation of sympathetic neurotransmission in the rat heart. IV. Effects guanethidine-induced sympathectomy on neonatal development of synaptic vesicles, synaptic terminal function and heart growth. 
  • Maximization of signal derived from cDNA microarrays. 
  • Mechanical culture conditions effect gene expression: gravity-induced changes on the space shuttle. 
  • Mechanism of estrogen action: early transcriptional and translational events. 
  • Mechanism of insulin gene regulation by the pancreatic transcription factor Pdx-1: application of pre-mRNA analysis and chromatin immunoprecipitation to assess formation of functional transcriptional complexes. 
  • Mechanisms of chromium-induced suppression of RNA synthesis in cellular and cell-free systems: relationship to RNA polymerase arrest. 
  • Mediation of meiotic and early mitotic chromosome segregation in Drosophila by a protein related to kinesin. 
  • Mesotheliomas induced in rats by the fibrous mineral erionite are independent from p53 alterations. 
  • Metallothionein abrogates GTP cyclohydrolase I inhibition-induced cardiac contractile and morphological defects: role of mitochondrial biogenesis. 
  • Methionine metabolism in health and cancer: a nexus of diet and precision medicine. 
  • Methods for the study of alternative splicing. 
  • MicroRNA target site identification by integrating sequence and binding information. 
  • Microarray analysis of gene expression in human donor sclera. 
  • Microarray-based comparison of three amplification methods for nanogram amounts of total RNA. 
  • Microinjection of Rap2B protein or RNA induces rearrangement of pigment granules in Xenopus oocytes. 
  • Microparticles as autoadjuvants in the pathogenesis of SLE. 
  • Mineralocorticoid receptor antagonists modulate galectin-3 and interleukin-33/ST2 signaling in left ventricular systolic dysfunction after acute myocardial infarction. 
  • Minor RNA and other components of host origin intrinsic to avian leukosis virus particles. 
  • Mitochondrial DNA structure and expression in specialized subtypes of mammalian striated muscle. 
  • Mitochondrial proteins that regulate apoptosis and necrosis are induced in mouse fatty liver. 
  • Mitotic phosphorylation of eukaryotic initiation factor 4G1 (eIF4G1) at Ser1232 by Cdk1:cyclin B inhibits eIF4A helicase complex binding with RNA. 
  • Model validation: local diagnosis, correction and when to quit. 
  • Modeling the developmental neurotoxicity of chlorpyrifos in vitro: macromolecule synthesis in PC12 cells. 
  • Modulating RNA Alignment Using Directional Dynamic Kinks: Application in Determining an Atomic-Resolution Ensemble for a Hairpin using NMR Residual Dipolar Couplings. 
  • Modulation of myocilin/TIGR expression in human trabecular meshwork. 
  • Molecular analysis of mutations in a patient with purine nucleoside phosphorylase deficiency. 
  • Molecular and immunohistochemical characterization of the onset and resolution of human renal allograft ischemia-reperfusion injury. 
  • Molecular basis of an inherited retinal defect in Drosophila. 
  • Molecular biology techniques and their applicability to the study of diabetes and hypertension: the renin-angiotensin system as an example. 
  • Molecular cloning and expression of the cDNA for the alpha 1A-adrenergic receptor. The gene for which is located on human chromosome 5. 
  • Molecular cloning and nucleotide sequence of cDNA encoding human muscle glycogen debranching enzyme. 
  • Molecular cloning of protein phosphatase inhibitor-1 and its expression in rat and rabbit tissues. 
  • Molecular cloning of rat glucose-dependent insulinotropic peptide (GIP). 
  • Molecular cloning of the cDNA for ligatin. 
  • Molecular composition of Ro small ribonucleoprotein complexes in human cells. Intracellular localization of the 60- and 52-kD proteins. 
  • Molecular structure of the La and Ro autoantigens and their use in autoimmune diagnostics. 
  • Morphological and biochemical changes which occur during postnatal development and maturation of the rat testis. 
  • Multivalent RNA aptamers that inhibit CTLA-4 and enhance tumor immunity. 
  • Murine polypyrimidine tract binding protein. Purification, cloning, and mapping of the RNA binding domain. 
  • Muscle sodium channel inactivation defect in paramyotonia congenita with the thr1313met mutation. 
  • Mutants resistant to LpxC inhibitors by rebalancing cellular homeostasis. 
  • Mutation analysis of the THRA1 gene in breast cancer: deletion/fusion of the gene to a novel sequence on 17q in the BT474 cell line. 
  • Mutational definition of functional domains within the Rev homolog encoded by human endogenous retrovirus K. 
  • Myosin light chain-2 luciferase transgenic mice reveal distinct regulatory programs for cardiac and skeletal muscle-specific expression of a single contractile protein gene. 
  • NMR studies of RNA dynamics and structural plasticity using NMR residual dipolar couplings. 
  • NMR studies of nucleic acid dynamics. 
  • New insights into the fundamental role of topological constraints as a determinant of two-way junction conformation. 
  • Nicotine is a developmental neurotoxicant and neuroprotectant: stage-selective inhibition of DNA synthesis coincident with shielding from effects of chlorpyrifos. 
  • Nonlinear interferometric vibrational imaging. 
  • North, south, or east? Blotting techniques. 
  • Novel RNA modifications in the nervous system: form and function. 
  • Novel late-onset Alzheimer disease loci variants associate with brain gene expression. 
  • Nuclear RNA export pathways. 
  • Nuclear RNA export. 
  • Nuclear RNA synthesis in sea urchin embryos. 
  • Nuclear RNA-binding proteins. 
  • Nuclear estrogen receptor in the avian liver: correlation with biologic response. 
  • Nucleocytoplasmic shuttling by protein nuclear import factors. 
  • Nucleotide sequences of the RNA subunit of RNase P from several mammals. 
  • OligoCalc: an online oligonucleotide properties calculator. 
  • Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis. 
  • Optimized lymphocyte protein extraction performed simultaneously with DNA and RNA isolation: application to the study of factors affecting DNA, RNA, and protein recovery from lymphocytes of the oldest individuals. 
  • Optimizing aptamer activity for gene therapy applications using expression cassette SELEX. 
  • Origin of overstretching transitions in single-stranded nucleic acids. 
  • Osteopontin-dependent CD44v6 expression and cell adhesion in HepG2 cells. 
  • PARalyzer: definition of RNA binding sites from PAR-CLIP short-read sequence data. 
  • Paternal deletion from Snrpn to Ube3a in the mouse causes hypotonia, growth retardation and partial lethality and provides evidence for a gene contributing to Prader-Willi syndrome. 
  • Patterns of expression of murine Vgr-1 and BMP-2a RNA suggest that transforming growth factor-beta-like genes coordinately regulate aspects of embryonic development. 
  • Patterns of gene expression that characterize long-term survival in advanced stage serous ovarian cancers. 
  • Perinatal dietary supplementation with a commercial soy lecithin preparation: effects on behavior and brain biochemistry in the developing rat. 
  • Peritoneal and subperitoneal stroma may facilitate regional spread of ovarian cancer. 
  • Phenotype correction of hemophilia A mice by spliceosome-mediated RNA trans-splicing. 
  • Phylogenetic analyses suggest reverse splicing spread of group I introns in fungal ribosomal DNA. 
  • Pleiotrophin regulates the ductular reaction by controlling the migration of cells in liver progenitor niches. 
  • Podocan, a novel small leucine-rich repeat protein expressed in the sclerotic glomerular lesion of experimental HIV-associated nephropathy. 
  • Positive and negative elements regulate human interleukin 3 expression. 
  • Postlipopolysaccharide oxidative damage of mitochondrial DNA. 
  • Postmortem delay has minimal effect on brain RNA integrity. 
  • Potential treatment for clubfeet based on growth factor blockade. 
  • Prediction of autism by translation and immune/inflammation coexpressed genes in toddlers from pediatric community practices. 
  • Prevalence of transcription promoters within archaeal operons and coding sequences. 
  • Probing motions between equivalent RNA domains using magnetic field induced residual dipolar couplings: accounting for correlations between motions and alignment. 
  • Probiotic administration reduces mortality and improves intestinal epithelial homeostasis in experimental sepsis. 
  • Processing of nuclear heterogeneous RNA: recent developments. 
  • Prognostic value of an RNA expression signature derived from cell cycle proliferation genes in patients with prostate cancer: a retrospective study. 
  • Proper function of the Drosophila trp gene product during pupal development is important for normal visual transduction in the adult. 
  • Properties of an intermediate-sized androgen receptor: association with RNA. 
  • Prospects for personalized cardiovascular medicine: the impact of genomics. 
  • Prostate intraepithelial neoplasia induced by prostate restricted Akt activation: the MPAKT model. 
  • Protection against oxidized low-density lipoprotein-induced vascular endothelial cell death by integrin-linked kinase. 
  • Protein biosynthesis in the testis. V. Concerning the mechanism of stimulation by follicle-stimulating hormone. 
  • Pseudouridine and N6-methyladenosine modifications weaken PUF protein/RNA interactions. 
  • Purkinje cell degeneration associated with erythroid ankyrin deficiency in nb/nb mice. 
  • Quantification of alternatively spliced FGFR2 RNAs using the RNA invasive cleavage assay. 
  • Quantification of microRNAs, splicing isoforms, and homologous mRNAs with the invader assay. 
  • Quantitative measurement of alternatively spliced amyloid precursor protein mRNA expression in Alzheimer's disease and normal brain by S1 nuclease protection analysis. 
  • R-BIND: An Interactive Database for Exploring and Developing RNA-Targeted Chemical Probes. 
  • RAD52 is required for RNA-templated recombination repair in post-mitotic neurons. 
  • RNA Structural Differentiation: Opportunities with Pattern Recognition. 
  • RNA Vaccination Therapy: Advances in an Emerging Field. 
  • RNA aptamer to thrombin binds anion-binding exosite-2 and alters protease inhibition by heparin-binding serpins. 
  • RNA aptamers as reversible antagonists of coagulation factor IXa. 
  • RNA as an RNA polymerase: net elongation of an RNA primer catalyzed by the Tetrahymena ribozyme. 
  • RNA as performance-enhancers for dendritic cells. 
  • RNA backbone is rotameric. 
  • RNA backbone rotamers--finding your way in seven dimensions. 
  • RNA backbone: consensus all-angle conformers and modular string nomenclature (an RNA Ontology Consortium contribution). 
  • RNA binding by Sxl proteins in vitro and in vivo. 
  • RNA dynamics by design: biasing ensembles towards the ligand-bound state. 
  • RNA dynamics: it is about time. 
  • RNA editing of the glutamate receptor subunits GluR2 and GluR6 in human brain tissue. 
  • RNA extraction from human articular cartilage by chondrocyte isolation. 
  • RNA inhibitors of nuclear proteins responsible for multiple organ dysfunction syndrome. 
  • RNA interference and single particle tracking analysis of hepatitis C virus endocytosis. 
  • RNA on the brain: emerging layers of post-transcriptional regulation in cerebral cortex development. 
  • RNA recognition by autoantigens and autoantibodies. 
  • RNA recognition: towards identifying determinants of specificity. 
  • RNA regulons: coordination of post-transcriptional events. 
  • RNA repair: a novel approach to gene therapy. 
  • RNA subunit of mitochondrial RNA-processing enzyme is induced by contractile activity in striated muscle. 
  • RNA surfaces as functional mimetics of proteins. 
  • RNA synthesis in liver nuclei of young rats fed varying amounts of vitamin A. 
  • RNA transfected dendritic cells as cancer vaccines. 
  • RNA-dependent stabilization of SUV39H1 at constitutive heterochromatin. 
  • RNA-transfected dendritic cells in cancer immunotherapy. 
  • RNA-transfected dendritic cells. 
  • RNABC: forward kinematics to reduce all-atom steric clashes in RNA backbone. 
  • RNA∶DNA hybrids initiate quasi-palindrome-associated mutations in highly transcribed yeast DNA. 
  • RacGap50C negatively regulates wingless pathway activity during Drosophila embryonic development. 
  • Randomization and selection of RNA to identify targets for RRM RNA-binding proteins and antibodies. 
  • Rapid Exchange Between Free and Bound States in RNA-Dendrimer Polyplexes: Implications on the Mechanism of Delivery and Release. 
  • Rapid identification of cell-specific, internalizing RNA aptamers with bioinformatics analyses of a cell-based aptamer selection. 
  • Receptor binding, endocytosis, and mitogenesis of insulin-like growth factors I and II in fetal rat brain neurons. 
  • Reduced dermatopontin expression is a molecular link between uterine leiomyomas and keloids. 
  • Reduction of folic acid-induced acute tubular injury by diuresis: an experimental model. 
  • Regulation of HIV-1 gene expression. 
  • Regulation of Kv1 subunit expression in oligodendrocyte progenitor cells and their role in G1/S phase progression of the cell cycle. 
  • Regulation of ornithine decarboxylase activity in the developing heart of euthyroid or hyperthyroid rats. 
  • Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence. 
  • Regulation of rat heart ornithine decarboxylase: change in affinity for ornithine evoked by neuronal, hormonal, and ontogenetic stimuli. 
  • Regulation of sugar transport in cultured diploid human skin fibroblasts. 
  • Regulation of the testis sertoli cell by follicle stimulating hormone. 
  • Relationship between adipose stromal-vascular cells and adipocytes in human adipose tissue. 
  • Remodelling chromatin with RNA. 
  • Reparative capacity of airway epithelium impacts deposition and remodeling of extracellular matrix. 
  • Resequencing Study Confirms That Host Defense and Cell Senescence Gene Variants Contribute to the Risk of Idiopathic Pulmonary Fibrosis. 
  • Resistance of pancreatic carcinoma cells is reversed by coculturing NK-like T cells with dendritic cells pulsed with tumor-derived RNA and CA 19-9. 
  • Resolving sugar puckers in RNA excited states exposes slow modes of repuckering dynamics. 
  • Restoration of the cystic fibrosis transmembrane conductance regulator function by splicing modulation. 
  • Resveratrol prevention of oxidative stress damage to lens epithelial cell cultures is mediated by forkhead box O activity. 
  • Rethinking m6A Readers, Writers, and Erasers. 
  • Reversible cross-linking combined with immunoprecipitation to study RNA-protein interactions in vivo. 
  • Rho kinase differentially regulates phosphorylation of nonmuscle myosin II isoforms A and B during cell rounding and migration. 
  • Ribose metabolism and nucleic acid synthesis in normal and glucose-6-phosphate dehydrogenase-deficient human erythrocytes infected with Plasmodium falciparum. 
  • Ribotrap : targeted purification of RNA-specific RNPs from cell lysates through immunoaffinity precipitation to identify regulatory proteins and RNAs. 
  • Ribozyme-mediated revision of RNA and DNA. 
  • Rodent model of reproductive tract leiomyomata. Establishment and characterization of tumor-derived cell lines. 
  • Role of decreased levels of lipid phosphate phosphatase-1 in accumulation of lysophosphatidic acid in ovarian cancer. 
  • Role of the Fas-signaling pathway in photoreceptor neuroprotection. 
  • SLICER: inferring branched, nonlinear cellular trajectories from single cell RNA-seq data. 
  • Saccharomyces cerevisiae killer virus transcripts contain template-coded polyadenylate tracts. 
  • Satellite DNA is transcribed on lampbrush chromosomes. 
  • Secretion and movement of wingless protein in the epidermis of the Drosophila embryo. 
  • Selection of an RNA molecule that mimics a major autoantigenic epitope of human insulin receptor. 
  • Selection of circularization sites in a group I IVS RNA requires multiple alignments of an internal template-like sequence. 
  • Selection of potential markers for epithelial ovarian cancer with gene expression arrays and recursive descent partition analysis. 
  • Selective regulation of expression of protein kinase C beta isoenzymes occurs via alternative splicing. 
  • Senataxin, A Novel Helicase at the Interface of RNA Transcriptome Regulation and Neurobiology: From Normal Function to Pathological Roles in Motor Neuron Disease and Cerebellar Degeneration. 
  • Sensing the impact of environment on small molecule differentiation of RNA sequences. 
  • Sequence complexity of nuclear RNAs in adult rat tissues. 
  • Sequence complexity of nuclear and cytoplasmic ribonucleic acids from clonal neurotumor cell lines and brain sections of the rat. 
  • Sequence requirements for Rev multimerization in vivo. 
  • Sequence requirements for micro RNA processing and function in human cells. 
  • Single- and dual-fractal analysis of hybridization binding kinetics: biosensor applications. 
  • Single-Cell RNA-seq Reveals a Subpopulation of Prostate Cancer Cells with Enhanced Cell-Cycle-Related Transcription and Attenuated Androgen Response. 
  • Single-stranded RNA facilitates nucleocapsid: APOBEC3G complex formation. 
  • Slowdown of Interhelical Motions Induces a Glass Transition in RNA. 
  • Smad5 induces ventral fates in Xenopus embryo. 
  • Spatially restricted patterns of expression of the homeobox-containing gene Hox 2.1. during mouse embryogenesis. 
  • Specific nuclear binding of adenosine 3',5'-monophosphate-binding protein complex with subsequent poly(A) RNA synthesis in embryonic chick cartilage. 
  • Specificity of anti-DNA antibodies induced in normal mice by immunization with bacterial DNA. 
  • Statistical analysis of RNA backbone. 
  • Stimulation of cartilage macromolecule synthesis by adenosine 3',5'-monophosphate. 
  • Stimulation of synthesis of ribonucleic acid in sub-apical sections of Avena coleoptile by indolyl-3-acetic acid. 
  • Structural analysis of the human BIN1 gene. Evidence for tissue-specific transcriptional regulation and alternate RNA splicing. 
  • Structural and transcriptional properties of different nucleosomal particles containing high mobility group proteins 14 and 17 (HMG 14/17). 
  • Structural dynamics of a single-stranded RNA-helix junction using NMR. 
  • Structural mechanism of Staphylococcus aureus Hfq binding to an RNA A-tract. 
  • Structure and specificity of the RNA-guided endonuclease Cas9 during DNA interrogation, target binding and cleavage. 
  • Structure of the Trypanosoma brucei p22 protein, a cytochrome oxidase subunit II-specific RNA-editing accessory factor. 
  • Structures of MERS1, the 5' processing enzyme of mitochondrial mRNAs in Trypanosoma brucei. 
  • Structures of the T. brucei kRNA editing factor MRB1590 reveal unique RNA-binding pore motif contained within an ABC-ATPase fold. 
  • Studies on mode of action of vitamin A. 
  • Subcellular partitioning of MRP RNA assessed by ultrastructural and biochemical analysis. 
  • Suppression of endo B cytokeratin by its antisense RNA inhibits the normal coexpression of endo A cytokeratin. 
  • Systematic analysis of posttranscriptional gene expression. 
  • TERC is not a major gene in human neural tube defects. 
  • Tagging ribozyme reaction sites to follow trans-splicing in mammalian cells. 
  • Targeted genetic repair: an emerging approach to genetic therapy. 
  • Targeted inhibition of alphavbeta3 integrin with an RNA aptamer impairs endothelial cell growth and survival. 
  • Targeted inhibition of calcineurin in pressure-overload cardiac hypertrophy. Preservation of systolic function. 
  • Targeting RNA in mammalian systems with small molecules. 
  • Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase. 
  • Telomerase reverse transcriptase is required for the localization of telomerase RNA to cajal bodies and telomeres in human cancer cells. 
  • Testosterone regulates cell proliferation in aggressive fibromatosis (desmoid tumour). 
  • Th1 inflammatory response with altered expression of profibrotic and vasoactive mediators in AT1A and AT1B double-knockout mice. 
  • The 5' and 3' splice sites come together via a three dimensional diffusion mechanism. 
  • The DNA sequence of the human X chromosome. 
  • The RNA Ontology Consortium: an open invitation to the RNA community. 
  • The RNAissance period. 
  • The RNase P associated with HeLa cell mitochondria contains an essential RNA component identical in sequence to that of the nuclear RNase P. 
  • The RRM of the kRNA-editing protein TbRGG2 uses multiple surfaces to bind and remodel RNA. 
  • The birth of the Epitranscriptome: deciphering the function of RNA modifications. 
  • The central role of nucleic acids in the pathogenesis of systemic lupus erythematosus. 
  • The claret locus in Drosophila encodes products required for eyecolor and for meiotic chromosome segregation. 
  • The clinical and environmental determinants of airway transcriptional profiles in allergic asthma. 
  • The cloning of GRK7, a candidate cone opsin kinase, from cone- and rod-dominant mammalian retinas. 
  • The content of DNA and RNA in microparticles released by Jurkat and HL-60 cells undergoing in vitro apoptosis. 
  • The crossroads of RNA regulation and function in neurodevelopment. 
  • The crystal structure and mutational analysis of a novel RNA-binding domain found in the human Tap nuclear mRNA export factor. 
  • The effect of a single boranophosphate substitution with defined configuration on the thermal stability and conformation of a DNA duplex. 
  • The effect of protein synthesis inhibition on the entry of messenger RNA into the cytoplasm of sea urchin embryos. 
  • The effects of ascorbic acid on cartilage metabolism in guinea pig articular cartilage explants. 
  • The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote. 
  • The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target. 
  • The molecular basis of disease variability among cystic fibrosis patients carrying the 3849+10 kb C-->T mutation. 
  • The murine winged helix transcription factors, Foxc1 and Foxc2, are both required for cardiovascular development and somitogenesis. 
  • The neuronatin gene resides in a "micro-imprinted" domain on human chromosome 20q11.2. 
  • The ortho effect makes manganese(III) meso-tetrakis(N-methylpyridinium-2-yl)porphyrin a powerful and potentially useful superoxide dismutase mimic. 
  • The phylogeny of extant starfish (Asteroidea: Echinodermata) including Xyloplax, based on comparative transcriptomics. 
  • The potassium channel MBK1 (Kv1.1) is expressed in the mouse retina. 
  • The prevalence and regulation of antisense transcripts in Schizosaccharomyces pombe. 
  • The properties of microparticles from RAW 264.7 macrophage cells undergoing in vitro activation or apoptosis. 
  • The ribonome: a dominant force in co-ordinating gene expression. 
  • The role of cAMP-dependent signaling in receptor-recognized forms of alpha 2-macroglobulin-induced cellular proliferation. 
  • The spliceosome assembly pathway in mammalian extracts. 
  • The spreading of X inactivation into autosomal material of an x;autosome translocation: evidence for a difference between autosomal and X-chromosomal DNA. 
  • The transcripts of zeta-crystallin, a lens protein related to the alcohol dehydrogenase family, are altered in a guinea-pig hereditary cataract. 
  • The virology-RNA biology connection. 
  • Tissue-specific expression in mammalian brain, heart, and muscle of S1, a member of the elongation factor-1 alpha gene family. 
  • Topological constraints: using RNA secondary structure to model 3D conformation, folding pathways, and dynamic adaptation. 
  • Topology links RNA secondary structure with global conformation, dynamics, and adaptation. 
  • Total RNA isolation by a rapid centrifugation method. 
  • Towards structural genomics of RNA: rapid NMR resonance assignment and simultaneous RNA tertiary structure determination using residual dipolar couplings. 
  • Trans-splicing reactions by ribozymes. 
  • Transcript length heterogeneity at the small heat shock protein genes of Drosophila. 
  • Transcription in mouse embryo cells permissively infected by murine cytomegalovirus. 
  • Transcriptional inhibition by carcinogenic chromate: relationship to DNA damage. 
  • Transcriptional network of multiple capsule and melanin genes governed by the Cryptococcus neoformans cyclic AMP cascade. 
  • Transcriptional profiling of whole blood and serum protein analysis of mice exposed to the neurotoxin Pacific Ciguatoxin-1. 
  • Transcriptomic Analysis of the Host Response and Innate Resilience to Enterotoxigenic Escherichia coli Infection in Humans. 
  • Transfecting Human Monocytes with RNA. 
  • Translational profiling of cardiomyocytes identifies an early Jak1/Stat3 injury response required for zebrafish heart regeneration. 
  • Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates. 
  • Tumor acquisition for biomarker research in lung cancer. 
  • Tuning physical properties of nanocomplexes through microfluidics-assisted confinement. 
  • Two biochemical markers in lymphocyte subpopulations. 
  • U1-snRNP-A protein selects a ten nucleotide consensus sequence from a degenerate RNA pool presented in various structural contexts. 
  • Understanding the Contributions of Conformational Changes, Thermodynamics, and Kinetics of RNA-Small Molecule Interactions. 
  • Unraveling the structural complexity in a single-stranded RNA tail: implications for efficient ligand binding in the prequeuosine riboswitch. 
  • Unveiling Inherent Degeneracies in Determining Population-Weighted Ensembles of Interdomain Orientational Distributions Using NMR Residual Dipolar Couplings: Application to RNA Helix Junction Helix Motifs. 
  • Up-regulation of recombination activating gene expression by signal transduction through the surface Ig receptor. 
  • Upregulation of IL-1β, IL-6, and CCL-2 by a novel mouse model of pancreatic ischemia-reperfusion injury. 
  • Urine RNA Processing in a Clinical Setting: Comparison of 3 Protocols. 
  • Use of SYTO 13, a fluorescent dye binding nucleic acids, for the detection of microparticles in in vitro systems. 
  • Utility of 1H NMR chemical shifts in determining RNA structure and dynamics. 
  • Validation of an RNA cell cycle progression score for predicting death from prostate cancer in a conservatively managed needle biopsy cohort. 
  • Vanilloid (capsaicin) receptors influence inflammatory sensitivity in response to particulate matter. 
  • Variable helix elongation as a tool to modulate RNA alignment and motional couplings. 
  • Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk. 
  • Variation in DNA and RNA synthetic responses during activation of lymphocytes from inbred strains of mice. 
  • Visualizing the formation of an RNA folding intermediate through a fast highly modular secondary structure switch. 
  • Visualizing transient Watson-Crick-like mispairs in DNA and RNA duplexes. 
  • Vitamin A supply and biochemical development of the rat heart: studies on cellular DNA, RNA and protein. 
  • Whole exome sequencing of a dominant retinitis pigmentosa family identifies a novel deletion in PRPF31. 
  • Whole genome expression profiling of normal human fetal and adult ocular tissues. 
  • Why are Hoogsteen base pairs energetically disfavored in A-RNA compared to B-DNA? 
  • XIST RNA paints the inactive X chromosome at interphase: evidence for a novel RNA involved in nuclear/chromosome structure. 
  • Y353/B: a candidate multiple-copy spermiogenesis gene on the mouse Y chromosome. 
  • ZCCHC8, the nuclear exosome targeting component, is mutated in familial pulmonary fibrosis and is required for telomerase RNA maturation. 
  • beta-Arrestin 2 expression determines the transcriptional response to lysophosphatidic acid stimulation in murine embryo fibroblasts. 
  • hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization. 
  • m(1)A and m(1)G disrupt A-RNA structure through the intrinsic instability of Hoogsteen base pairs. 
  • permGPU: Using graphics processing units in RNA microarray association studies. 
• 

  Keywords of People

  • Been, Michael Douglas, Professor Emeritus of Biochemistry, Biochemistry
  • Bennett, Vann, George Barth Geller Distinguished Professor of Molecular Biology, Duke Cancer Institute
  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Buckley, Rebecca Hatcher, James Buren Sidbury Distinguished Professor of Pediatrics, in the School of Medicine, Immunology
  • Hartemink, Alexander J., Professor in the Department of Computer Science, Biology
  • Hogan, Brigid L. M., George Barth Geller Distinguished Professor of Immunology, Cell Biology
  • Liu, Yutao, Adjunct Assistant Professor in the Department of Medicine, Medicine, Medical Genetics
  • Luftig, Micah Alan, Associate Professor of Molecular Genetics and Microbiology, Immunology
  • McLendon, Roger Edwin, Professor of Pathology, Pathology
  • Meyer, Kathryn, Assistant Professor of Biochemistry, Neurobiology
  • Richardson, David C., Professor of Biochemistry, Biochemistry
  • Roy Choudhury, Kingshuk, Adjunct Associate Professor in the Department of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics
  • Swaminathan, Madhav, Professor of Anesthesiology, Anesthesiology, Cardiothoracic
  • Weinhold, Kent James, Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery, in the School of Medicine, Immunology