RNA, Fungal

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  Subject Areas on Research

  • A bifunctional dihydrofolate synthetase--folylpolyglutamate synthetase in Plasmodium falciparum identified by functional complementation in yeast and bacteria. 
  • A cell cycle checkpoint monitors cell morphogenesis in budding yeast. 
  • A cyclin B homolog in S. cerevisiae: chronic activation of the Cdc28 protein kinase by cyclin prevents exit from mitosis. 
  • A non-canonical RNA degradation pathway suppresses RNAi-dependent epimutations in the human fungal pathogen Mucor circinelloides. 
  • A phospholipase C-dependent inositol polyphosphate kinase pathway required for efficient messenger RNA export. 
  • A small yeast RNA blocks hepatitis C virus internal ribosome entry site (HCV IRES)-mediated translation and inhibits replication of a chimeric poliovirus under translational control of the HCV IRES element. 
  • ACE1, a copper-dependent transcription factor, activates expression of the yeast copper, zinc superoxide dismutase gene. 
  • ACE2, an activator of yeast metallothionein expression which is homologous to SWI5. 
  • Analysis of genes coding for small-subunit rRNA sequences in studying phylogenetics of dematiaceous fungal pathogens. 
  • Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation. 
  • Analyzing transcription dynamics during the budding yeast cell cycle. 
  • Broad antifungal resistance mediated by RNAi-dependent epimutation in the basal human fungal pathogen Mucor circinelloides. 
  • Cdc28 tyrosine phosphorylation and the morphogenesis checkpoint in budding yeast. 
  • Cell biology: How to combat stress. 
  • Circadian clock-controlled genes isolated from Neurospora crassa are late night- to early morning-specific. 
  • Comparison of 5.8S ribosomal DNA sequences among the basidiomycetous yeast genera Cystofilobasidium, Filobasidium and Filobasidiella. 
  • Comparison of ribosomal DNA ITS regions among geographic isolates of Cenococcum geophilum. 
  • Cotranscriptional association of mRNA export factor Yra1 with C-terminal domain of RNA polymerase II. 
  • Cryptococcus neoformans methionine synthase: expression analysis and requirement for virulence. 
  • Differential surface localization and temperature-dependent expression of the Candida albicans CSH1 protein. 
  • Disruption of ergosterol biosynthesis confers resistance to amphotericin B in Candida lusitaniae. 
  • Distinct microbial communities within the endosphere and rhizosphere of Populus deltoides roots across contrasting soil types. 
  • Ectomycorrhizal fungal diversity in orchards of cultivated pecan (Carya illinoinensis; Juglandaceae). 
  • Effect of alpha-isopropylmalate on the synthesis of RNA and protein in Neurospora. 
  • Effect of the laccase gene CNLAC1, on virulence of Cryptococcus neoformans. 
  • Elevated Genome-Wide Instability in Yeast Mutants Lacking RNase H Activity. 
  • Evolutionary relationships within the fungi: analyses of nuclear small subunit rRNA sequences. 
  • Ferrochelatase is a conserved downstream target of the blue light-sensing White collar complex in fungi. 
  • Genome-wide analysis of the regulation of Cu metabolism in Cryptococcus neoformans. 
  • Identification and analysis of a Saccharomyces cerevisiae copper homeostasis gene encoding a homeodomain protein. 
  • Identification and characterization of rns4/vps32 mutation in the RNase T1 expression-sensitive strain of Saccharomyces cerevisiae: Evidence for altered ambient response resulting in transportation of the secretory protein to vacuoles. 
  • Identification and characterization of upstream open reading frames (uORF) in the 5' untranslated regions (UTR) of genes in Saccharomyces cerevisiae. 
  • Identification of an apparent aminoacyl-tRNA synthetase activator factor as tRNA nucleotidyltransferase. 
  • Identification of the yeast cytidine deaminase CDD1 as an orphan C-->U RNA editase. 
  • Impact of ammonium permeases mepA, mepB, and mepC on nitrogen-regulated secondary metabolism in Fusarium fujikuroi. 
  • Implementing a cumulative supermatrix approach for a comprehensive phylogenetic study of the Teloschistales (Pezizomycotina, Ascomycota). 
  • Insights into evolution of multicellular fungi from the assembled chromosomes of the mushroom Coprinopsis cinerea (Coprinus cinereus). 
  • Interactions of TLC1 (which encodes the RNA subunit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae. 
  • Kin28, the TFIIH-associated carboxy-terminal domain kinase, facilitates the recruitment of mRNA processing machinery to RNA polymerase II. 
  • Major fungal lineages are derived from lichen symbiotic ancestors. 
  • Mammalian RAFT1 kinase domain provides rapamycin-sensitive TOR function in yeast. 
  • Mating type (MAT) locus and possible sexuality of the opportunistic pathogen Exophiala dermatitidis. 
  • Messenger RNA intron in the nuclear 18s ribosomal RNA gene of deuteromycetes. 
  • Molecular characterization of the spatial diversity and novel lineages of mycoplankton in Hawaiian coastal waters. 
  • New species and distribution records for Clavulina (Cantharellales, Basidiomycota) from the Guiana Shield, with a key to the lowland neotropical taxa. 
  • Non-coding RNA prediction and verification in Saccharomyces cerevisiae. 
  • Novel stress-responsive genes EMG1 and NOP14 encode conserved, interacting proteins required for 40S ribosome biogenesis. 
  • Numerous group I introns with variable distributions in the ribosomal DNA of a lichen fungus. 
  • Phylogenetic relationships in the mushroom genus Coprinus and dark-spored allies based on sequence data from the nuclear gene coding for the large ribosomal subunit RNA: divergent domains, outgroups, and monophyly. 
  • Phylogenomic analysis of non-ribosomal peptide synthetases in the genus Aspergillus. 
  • Post-transcriptional regulation of gene expression in response to iron deficiency: co-ordinated metabolic reprogramming by yeast mRNA-binding proteins. 
  • Proteome-wide search reveals unexpected RNA-binding proteins in Saccharomyces cerevisiae. 
  • RNA-based analyses reveal fungal communities structured by a senescence gradient in the moss Dicranum scoparium and the presence of putative multi-trophic fungi. 
  • Recombination of plasmids into the Saccharomyces cerevisiae chromosome is reduced by small amounts of sequence heterogeneity. 
  • Ribotrap : targeted purification of RNA-specific RNPs from cell lysates through immunoaffinity precipitation to identify regulatory proteins and RNAs. 
  • Sequences within a small yeast RNA required for inhibition of internal initiation of translation: interaction with La and other cellular proteins influences its inhibitory activity. 
  • Sequences within the spacer region of yeast rRNA cistrons that stimulate 35S rRNA synthesis in vivo mediate RNA polymerase I-dependent promoter and terminator activities. 
  • Sequential elimination of major-effect contributors identifies additional quantitative trait loci conditioning high-temperature growth in yeast. 
  • The Cryptococcus neoformans transcriptome at the site of human meningitis. 
  • The MEP2 ammonium permease regulates pseudohyphal differentiation in Saccharomyces cerevisiae. 
  • The calmodulin-dependent protein phosphatase catalytic subunit (calcineurin A) is an essential gene in Aspergillus nidulans. 
  • The secretory pathway in control of endoplasmic reticulum homeostasis. 
  • The suppressor gene scl1+ of Saccharomyces cerevisiae is essential for growth. 
  • Threonine biosynthetic genes are essential in Cryptococcus neoformans. 
  • Variation in modes and rates of evolution in nuclear and mitochondrial ribosomal DNA in the mushroom genus Amanita (Agaricales, Basidiomycota): phylogenetic implications. 
  • Verification of a new gene on Saccharomyces cerevisiae chromosome III. 
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  Keywords of People

  • Shinohara, Mari L., Associate Professor of Immunology, Immunology