RNA, Small Nuclear
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Subject Areas on Research
- A compensatory base change in U1 snRNA suppresses a 5' splice site mutation.
- A compensatory base change in human U2 snRNA can suppress a branch site mutation.
- A rare example of lock-and-key RNA recognition.
- A sequence-specific conformational epitope on U1 RNA is recognized by a unique autoantibody.
- A specific 31-nucleotide domain of U1 RNA directly interacts with the 70K small nuclear ribonucleoprotein component.
- An ATP-independent U2 small nuclear ribonucleoprotein particle/precursor mRNA complex requires both splice sites and the polypyrimidine tract.
- Anti-U1A monoclonal antibodies recognize unique epitope targets of U1A which are involved in the binding of U1 RNA.
- Autoantibodies specific for U1 RNA and initiator methionine tRNA.
- Characterization of immunophilins in the silkmoth Bombyx mori.
- Connections between the processing and nuclear export of mRNA: evidence for an export license?
- Downregulation of RNA polymerase III transcription of the hY3 gene in vitro.
- Expression of autoantibodies to recombinant (U1) RNP-associated 70K antigen in systemic lupus erythematosus.
- Group-I intron family in the nuclear ribosomal RNA small subunit genes of Cenococcum geophilum isolates.
- In vitro RNA selection of an autoimmune epitope on stem-loop II of U1 RNA.
- In vitro selection of RNA epitopes using autoimmune patient serum.
- In vitro selection of an RNA epitope immunologically cross-reactive with a peptide.
- Inhibitory effects of vesicular stomatitis virus on cellular and influenza viral RNA metabolism and protein synthesis.
- Interactions between small viral RNAs of vesicular stomatitis virus and components of cellular gene expression.
- Leucine periodicity of U2 small nuclear ribonucleoprotein particle (snRNP) A' protein is implicated in snRNP assembly via protein-protein interactions.
- Quantitative determination that one of two potential RNA-binding domains of the A protein component of the U1 small nuclear ribonucleoprotein complex binds with high affinity to stem-loop II of U1 RNA.
- RNA binding specificity of a Drosophila snRNP protein that shares sequence homology with mammalian U1-A and U2-B" proteins.
- RNA-binding domain of the A protein component of the U1 small nuclear ribonucleoprotein analyzed by NMR spectroscopy is structurally similar to ribosomal proteins.
- Randomization and selection of RNA to identify targets for RRM RNA-binding proteins and antibodies.
- Recognition of U-rich RNA by Hfq from the Gram-positive pathogen Listeria monocytogenes.
- Recognition of U1 and U2 small nuclear RNAs can be altered by a 5-amino-acid segment in the U2 small nuclear ribonucleoprotein particle (snRNP) B" protein and through interactions with U2 snRNP-A' protein.
- Rpl13a small nucleolar RNAs regulate systemic glucose metabolism.
- The carboxy terminal WD domain of the pre-mRNA splicing factor Prp17p is critical for function.
- The natural 5' splice site of simian virus 40 large T antigen can be improved by increasing the base complementarity to U1 RNA.
- Trans-activating rev protein of the human immunodeficiency virus 1 interacts directly and specifically with its target RNA.
- U1 small nuclear RNA variants differentially form ribonucleoprotein particles in vitro.
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Keywords of People
- Shinohara, Mari L., Associate Professor of Immunology, Immunology