S-Adenosylmethionine
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Subject Areas on Research
- A chemical method for labeling lysine methyltransferase substrates.
- A mathematical model gives insights into nutritional and genetic aspects of folate-mediated one-carbon metabolism.
- A mathematical model of the methionine cycle.
- Altered regulation of S-adenosylmethionine dependent methylation in adenosine deaminase deficiency.
- Behavioral and neurochemical changes in folate-deficient mice.
- Binding of MetJ repressor to specific and nonspecific DNA and effect of S-adenosylmethionine on these interactions.
- Blood biomarkers of methylation in Down syndrome and metabolic simulations using a mathematical model.
- C-C bond forming radical SAM enzymes involved in the construction of carbon skeletons of cofactors and natural products.
- Carbon extension in peptidylnucleoside biosynthesis by radical SAM enzymes.
- Cellular stress signaling activates type-I IFN response through FOXO3-regulated lamin posttranslational modification.
- Characterization and mechanistic study of a radical SAM dehydrogenase in the biosynthesis of butirosin.
- Characterization of a Radical SAM Oxygenase for the Ether Crosslinking in Darobactin Biosynthesis.
- Conservation and functional importance of carbon-oxygen hydrogen bonding in AdoMet-dependent methyltransferases.
- Decreased DNA methyltransferase 3A and 3B mRNA expression in peripheral blood mononuclear cells and increased plasma SAH concentration in adult patients with idiopathic thrombocytopenic purpura.
- Direct evidence for methyl group coordination by carbon-oxygen hydrogen bonds in the lysine methyltransferase SET7/9.
- Histone Methylation Dynamics and Gene Regulation Occur through the Sensing of One-Carbon Metabolism.
- In vitro synthesis of messenger RNA by a defective interfering particle of vesicular stomatitis virus.
- Increased Ca2+ -ATPase activity associated with methylation of phospholipids in human erythrocytes.
- Influence of threonine metabolism on S-adenosylmethionine and histone methylation.
- Manipulating unconventional CH-based hydrogen bonding in a methyltransferase via noncanonical amino acid mutagenesis.
- Mechanism of Rate Acceleration of Radical C-C Bond Formation Reaction by a Radical SAM GTP 3',8-Cyclase.
- Mechanism of Reduction of an Aminyl Radical Intermediate in the Radical SAM GTP 3',8-Cyclase MoaA.
- Mechanistic study on the reaction of a radical SAM dehydrogenase BtrN by electron paramagnetic resonance spectroscopy.
- Methionine metabolism is essential for SIRT1-regulated mouse embryonic stem cell maintenance and embryonic development.
- Nonpharmacologic treatments for depression in patients with coronary heart disease.
- One-carbon metabolism and epigenetics: understanding the specificity.
- One-carbon metabolism during the menstrual cycle and pregnancy
- One-methyl group metabolism in non-ketotic hyperglycinaemia: mildly elevated cerebrospinal fluid homocysteine levels.
- Paradigm Shift for Radical S-Adenosyl-l-methionine Reactions: The Organometallic Intermediate Ω Is Central to Catalysis.
- Perturbations in S-adenosylhomocysteine and S-adenosylmethionine metabolism: effects on transmethylation.
- Phospholipid methylation unmasks cryptic beta-adrenergic receptors in rat reticulocytes.
- Radical Breakthroughs in Natural Product and Cofactor Biosynthesis.
- Regulation of beta-adrenergic receptors by phospholipid methylation.
- Regulation of mononuclear leukocyte function by transmethylation reactions.
- Requirement of S-adenosyl-L-methionine-mediated methylation for human monocyte chemotaxis.
- Role of transmethylation reactions in cellular motility and phagocytosis.
- Selenocysteine substitutions in thiyl radical enzymes.
- Serotonin-induced hypersensitivity via inhibition of catechol O-methyltransferase activity.
- Structural and Functional Characterization of Sulfonium Carbon-Oxygen Hydrogen Bonding in the Deoxyamino Sugar Methyltransferase TylM1.
- Structural basis for the differential regulation of DNA by the methionine repressor MetJ.
- Structural mechanism of S-adenosyl methionine binding to catechol O-methyltransferase.
- Structure determination of selenomethionyl S-adenosylhomocysteine hydrolase using data at a single wavelength.
- Structure-guided DOT1L probe optimization by label-free ligand displacement.
- The mouse lethal nonagouti (a(x)) mutation deletes the S-adenosylhomocysteine hydrolase (Ahcy) gene.
- The relationship between intracellular and plasma levels of folate and metabolites in the methionine cycle: a model.
- Thermodynamic evaluation of binding interactions in the methionine repressor system of Escherichia coli using isothermal titration calorimetry.
- Transmethylation reactions regulate affinity and functional activity of chemotactic factor receptors on macrophages.
- Water-Mediated Carbon-Oxygen Hydrogen Bonding Facilitates S-Adenosylmethionine Recognition in the Reactivation Domain of Cobalamin-Dependent Methionine Synthase.
- [The role of DNA methylation in the pathogenesis of adult idiopathic thrombocytopenic purpura].