Saccharomyces cerevisiae

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  Subject Areas on Research

  • 14-3-3 proteins are part of an abscisic acid-VIVIPAROUS1 (VP1) response complex in the Em promoter and interact with VP1 and EmBP1. 
  • 4-oxatetradecanoic acid is fungicidal for Cryptococcus neoformans and inhibits replication of human immunodeficiency virus I. 
  • A GH3-like domain in reaper is required for mitochondrial localization and induction of IAP degradation. 
  • A High-Throughput Mutational Scan of an Intrinsically Disordered Acidic Transcriptional Activation Domain. 
  • A Mep2-dependent transcriptional profile links permease function to gene expression during pseudohyphal growth in Saccharomyces cerevisiae. 
  • A PAK-like protein kinase is required for maturation of young hyphae and septation in the filamentous ascomycete Ashbya gossypii. 
  • A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine. 
  • A catalog of neutral and deleterious polymorphism in yeast. 
  • A cell-nonautonomous mechanism of yeast chronological aging regulated by caloric restriction and one-carbon metabolism. 
  • A chimeric kinesin-1 head/kinesin-5 tail motor switches between diffusive and processive motility. 
  • A colony color method identifies the vulnerability of mitochondria to oxidative damage. 
  • A conserved alternative splice in the von Recklinghausen neurofibromatosis (NF1) gene produces two neurofibromin isoforms, both of which have GTPase-activating protein activity. 
  • A conserved family of enzymes that phosphorylate inositol hexakisphosphate. 
  • A constitutively active GPCR governs morphogenic transitions in Cryptococcus neoformans. 
  • A critical role of two positively charged amino acids in the Jas motif of Arabidopsis JAZ proteins in mediating coronatine- and jasmonoyl isoleucine-dependent interactions with the COI1 F-box protein. 
  • A developmentally regulated translational control pathway establishes the meiotic chromosome segregation pattern. 
  • A family of ubiquitin-like proteins binds the ATPase domain of Hsp70-like Stch. 
  • A fine-structure map of spontaneous mitotic crossovers in the yeast Saccharomyces cerevisiae. 
  • A functional proteomics approach to signal transduction. 
  • A generalized model for multi-marker analysis of cell cycle progression in synchrony experiments. 
  • A genetic analysis of nitrosative stress. 
  • A genome-wide visual screen reveals a role for sphingolipids and ergosterol in cell surface delivery in yeast. 
  • A glucan synthase FKS1 homolog in cryptococcus neoformans is single copy and encodes an essential function. 
  • A high-performance liquid chromatographic method to measure sphingosine 1-phosphate and related compounds from sphingosine kinase assays and other biological samples. 
  • A library approach for the discovery of customized yeast three-hybrid counter selections. 
  • A metabolic enzyme for S-nitrosothiol conserved from bacteria to humans. 
  • A molecular basis for inositol polyphosphate synthesis in Drosophila melanogaster. 
  • A mutation of the yeast gene encoding PCNA destabilizes both microsatellite and minisatellite DNA sequences. 
  • A new SOD mimic, Mn(III) ortho N-butoxyethylpyridylporphyrin, combines superb potency and lipophilicity with low toxicity. 
  • A new face of the Rhesus antigen. 
  • A novel domain in Set2 mediates RNA polymerase II interaction and couples histone H3 K36 methylation with transcript elongation. 
  • A novel dwarfing mutation in a green revolution gene from Brassica rapa. 
  • A novel narnavirus is widespread in Saccharomyces cerevisiae and impacts multiple host phenotypes. 
  • A novel structural form of the 2 micron plasmid of the yeast Saccharomyces cerevisiae. 
  • A novel, highly regulated, rapidly inducible system for the expression of chicken progesterone receptor, cPRA, in Saccharomyces cerevisiae. 
  • A nucleosome-guided map of transcription factor binding sites in yeast. 
  • A phospholipase C-dependent inositol polyphosphate kinase pathway required for efficient messenger RNA export. 
  • A probabilistic model for cell cycle distributions in synchrony experiments. 
  • A promoter deletion reduces the rate of mitotic, but not meiotic, recombination at the HIS4 locus in yeast. 
  • A protein kinase that phosphorylates the C-terminal repeat domain of the largest subunit of RNA polymerase II. 
  • A proteomics approach to the identification of mammalian mitochondrial small subunit ribosomal proteins. 
  • A role for nuclear inositol 1,4,5-trisphosphate kinase in transcriptional control. 
  • A single base substitution in the variable pocket of yeast tRNA(Arg) eliminates species-specific aminoacylation. 
  • A yeast cyclophilin gene essential for lactate metabolism at high temperature. 
  • A yeast expression system for human galactose-1-phosphate uridylyltransferase. 
  • ATM binds to beta-adaptin in cytoplasmic vesicles. 
  • ATP-sensitive K+ channels in a plasma membrane H+-ATPase mutant of the yeast Saccharomyces cerevisiae. 
  • Abasic sites in the transcribed strand of yeast DNA are removed by transcription-coupled nucleotide excision repair. 
  • Aberrant processing of the WSC family and Mid2p cell surface sensors results in cell death of Saccharomyces cerevisiae O-mannosylation mutants. 
  • Absolute Arrangement of Subunits in Cytoskeletal Septin Filaments in Cells Measured by Fluorescence Microscopy. 
  • Acquisition and processing of a conditional dicentric chromosome in Saccharomyces cerevisiae. 
  • Additive estrogenic activities of a binary mixture of 2',4',6'-trichloro- and 2',3',4',5'-tetrachloro-4-biphenylol. 
  • All cyclophilins and FK506 binding proteins are, individually and collectively, dispensable for viability in Saccharomyces cerevisiae. 
  • Alleles of the yeast Pms1 mismatch-repair gene that differentially affect recombination- and replication-related processes. 
  • Allelic and ectopic interactions in recombination-defective yeast strains. 
  • Allelic and ectopic recombination between Ty elements in yeast. 
  • Allosteric modulation of nucleoporin assemblies by intrinsically disordered regions. 
  • Alteration of lithium pharmacology through manipulation of phosphoadenosine phosphate metabolism. 
  • Amino acid changes in Xrs2p, Dun1p, and Rfa2p that remove the preferred targets of the ATM family of protein kinases do not affect DNA repair or telomere length in Saccharomyces cerevisiae. 
  • Amino acid permeases require COPII components and the ER resident membrane protein Shr3p for packaging into transport vesicles in vitro. 
  • An Antifungal Combination Matrix Identifies a Rich Pool of Adjuvant Molecules that Enhance Drug Activity against Diverse Fungal Pathogens. 
  • An engineered Saccharomyces cerevisiae strain binds the broadly neutralizing human immunodeficiency virus type 1 antibody 2G12 and elicits mannose-specific gp120-binding antibodies. 
  • An essential role for Mad homology domain 1 in the association of Smad3 with histone deacetylase activity*. 
  • An examination of adaptive reversion in Saccharomyces cerevisiae. 
  • Analysis of APOBEC-induced mutations in yeast strains with low levels of replicative DNA polymerases. 
  • Analysis of a gene conversion gradient at the HIS4 locus in Saccharomyces cerevisiae. 
  • Analysis of candidate antagonists of IAP-mediated caspase inhibition using yeast reconstituted with the mammalian Apaf-1-activated apoptosis mechanism. 
  • Analysis of meiotic recombination events near a recombination hotspot in the yeast Saccharomyces cerevisiae. 
  • Analysis of microsatellite mutations in the mitochondrial DNA of Saccharomyces cerevisiae. 
  • Analysis of the junction between ribosomal RNA genes and single-copy chromosomal sequences in the yeast Saccharomyces cerevisiae. 
  • Analysis of the proteins involved in the in vivo repair of base-base mismatches and four-base loops formed during meiotic recombination in the yeast Saccharomyces cerevisiae. 
  • Antibiotic and antimalarial quinones from fungus-growing ant-associated Pseudonocardia sp. 
  • Antiestrogen can establish nonproductive receptor complexes and alter chromatin structure at target enhancers. 
  • Antifungal effects of cyclosporine and FK 506 are mediated via immunophilin-dependent calcineurin inhibition. 
  • Aquaglyceroporin AQP9: solute permeation and metabolic control of expression in liver. 
  • Aquaporins in Saccharomyces. Genetic and functional distinctions between laboratory and wild-type strains. 
  • Aromatic hydrocarbon receptor polymorphism: development of new methods to correlate genotype with phenotype. 
  • Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9. 
  • Ashbya Genome Database 3.0: a cross-species genome and transcriptome browser for yeast biologists. 
  • Assaying CTD kinases in vitro and phosphorylation-modulated properties of RNA polymerase II in vivo. 
  • Assessing transcription factor motif drift from noisy decoy sequences. 
  • Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans. 
  • Association of increased spontaneous mutation rates with high levels of transcription in yeast. 
  • B-cyclin/CDKs regulate mitotic spindle assembly by phosphorylating kinesins-5 in budding yeast. 
  • Base composition of mononucleotide runs affects DNA polymerase slippage and removal of frameshift intermediates by mismatch repair in Saccharomyces cerevisiae. 
  • Bi-allelic KARS1 pathogenic variants affecting functions of cytosolic and mitochondrial isoforms are associated with a progressive and multisystem disease. 
  • Biolistic nuclear transformation of Saccharomyces cerevisiae and other fungi. 
  • Branched-Chain Aminotransferases Control TORC1 Signaling in Saccharomyces cerevisiae. 
  • Branching process deconvolution algorithm reveals a detailed cell-cycle transcription program. 
  • CD30 contains two binding sites with different specificities for members of the tumor necrosis factor receptor-associated factor family of signal transducing proteins. 
  • CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1. 
  • CNS1 encodes an essential p60/Sti1 homolog in Saccharomyces cerevisiae that suppresses cyclophilin 40 mutations and interacts with Hsp90. 
  • COPII and secretory cargo capture into transport vesicles. 
  • COPII-cargo interactions direct protein sorting into ER-derived transport vesicles. 
  • CTD kinase large subunit is encoded by CTK1, a gene required for normal growth of Saccharomyces cerevisiae. 
  • Calcineurin Targets Involved in Stress Survival and Fungal Virulence. 
  • Calcineurin is essential in cyclosporin A- and FK506-sensitive yeast strains. 
  • Calcium binding is required for calmodulin function in Aspergillus nidulans. 
  • Calcium-myristoyl switches turn on new lights. 
  • Calmodulin dissociation regulates Myo5 recruitment and function at endocytic sites. 
  • Cancer-associated isocitrate dehydrogenase mutations induce mitochondrial DNA instability. 
  • Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex. 
  • Casein kinase II copurifies with yeast DNA topoisomerase II and re-activates the dephosphorylated enzyme. 
  • Casein kinase II phosphorylates the eukaryote-specific C-terminal domain of topoisomerase II in vivo. 
  • Caspase-3 cleavage links delta-catenin to the novel nuclear protein ZIFCAT. 
  • Cationic amphiphilic Zn-porphyrin with high antifungal photodynamic potency. 
  • Causal Genetic Variation Underlying Metabolome Differences. 
  • Cch1 mediates calcium entry in Cryptococcus neoformans and is essential in low-calcium environments. 
  • Cell biology. A fungal Achilles' heel. 
  • Cell biology. Cells listen to their inner voice. 
  • Cell biology: How to combat stress. 
  • Cell cycle progression in G1 and S phases is CCR4 dependent following ionizing radiation or replication stress in Saccharomyces cerevisiae. 
  • Cell cycle-regulated transcription: effectively using a genomics toolbox. 
  • Cell surface polarization during yeast mating. 
  • Cell-Cycle-Dependent Chromatin Dynamics at Replication Origins. 
  • Cellular mechanisms regulating protein phosphatase-1. A key functional interaction between inhibitor-2 and the type 1 protein phosphatase catalytic subunit. 
  • Cellular response to endoplasmic reticulum stress: a matter of life or death. 
  • Challenge of Drosophila melanogaster with Cryptococcus neoformans and role of the innate immune response. 
  • Characterization and expression of a rice RAD23 gene. 
  • Characterization of G25K, a GTP-binding protein containing a novel putative nucleotide binding domain. 
  • Characterization of a mutation in yeast causing nonrandom chromosome loss during mitosis. 
  • Characterization of a selective inhibitor of inositol hexakisphosphate kinases: use in defining biological roles and metabolic relationships of inositol pyrophosphates. 
  • Characterization of alcohol-induced filamentous growth in Saccharomyces cerevisiae. 
  • Characterization of avian and viral p60src proteins expressed in yeast. 
  • Characterization of dependencies between growth and division in budding yeast. 
  • Characterization of long G4-rich enhancer-associated genomic regions engaging in a novel loop:loop 'G4 Kissing' interaction. 
  • Characterization of the Saccharomyces cerevisiae ATP-Interactome using the iTRAQ-SPROX Technique. 
  • Characterization of the energy-dependent, mating factor-activated Ca2+ influx in Saccharomyces cerevisiae. 
  • Characterization of the repeat-tract instability and mutator phenotypes conferred by a Tn3 insertion in RFC1, the large subunit of the yeast clamp loader. 
  • Characterization of two types of yeast ribosomal DNA genes. 
  • Charged residues on the side of the nucleosome contribute to normal Spt16-gene interactions in budding yeast. 
  • Checkpoints couple transcription network oscillator dynamics to cell-cycle progression. 
  • Chicken progesterone receptor expressed in Saccharomyces cerevisiae is correctly phosphorylated at all four Ser-Pro phosphorylation sites. 
  • Chromatin conformation of yeast centromeres 
  • Chromosomal rearrangements accompanying yeast mating-type switching: evidence for a gene-conversion model. 
  • Chromosomal translocations generated by high-frequency meiotic recombination between repeated yeast genes. 
  • Chromosomal translocations in yeast induced by low levels of DNA polymerase a model for chromosome fragile sites. 
  • Chromosome aberrations resulting from double-strand DNA breaks at a naturally occurring yeast fragile site composed of inverted ty elements are independent of Mre11p and Sae2p. 
  • Chromosome fragility at GAA tracts in yeast depends on repeat orientation and requires mismatch repair. 
  • Chromosome rearrangements and aneuploidy in yeast strains lacking both Tel1p and Mec1p reflect deficiencies in two different mechanisms. 
  • Chromosome rearrangements via template switching between diverged repeated sequences. 
  • Chronic oxidative DNA damage due to DNA repair defects causes chromosomal instability in Saccharomyces cerevisiae. 
  • Clathrin is important for normal actin dynamics and progression of Sla2p-containing patches during endocytosis in yeast. 
  • Cloning and characterization of ATRAP, a novel protein that interacts with the angiotensin II type 1 receptor. 
  • Cloning and characterization of a mammalian lithium-sensitive bisphosphate 3'-nucleotidase inhibited by inositol 1,4-bisphosphate. 
  • Cloning and characterization of two yeast genes encoding members of the CCCH class of zinc finger proteins: zinc finger-mediated impairment of cell growth. 
  • Cloning and expression of the yeast plasma membrane ATPase in Escherichia coli. 
  • Cloning the Cryptococcus neoformans TRP1 gene by complementation in Saccharomyces cerevisiae. 
  • Coat proteins and selective protein packaging into transport vesicles. 
  • Collaborative interactions between MEF-2 and Sp1 in muscle-specific gene regulation. 
  • Compact organization of rRNA genes in the filamentous fungus Ashbya gossypii. 
  • Comparative electrokinetic properties of extracellular vesicles produced by yeast and bacteria. 
  • Comparative genome-wide screening identifies a conserved doxorubicin repair network that is diploid specific in Saccharomyces cerevisiae. 
  • Comparative pathogenesis of clinical and nonclinical isolates of Saccharomyces cerevisiae. 
  • Comparison of in vitro activities of camptothecin and nitidine derivatives against fungal and cancer cells. 
  • Comparison of myristoyl-CoA:protein N-myristoyltransferases from three pathogenic fungi: Cryptococcus neoformans, Histoplasma capsulatum, and Candida albicans. 
  • Competition between adjacent meiotic recombination hotspots in the yeast Saccharomyces cerevisiae. 
  • Complex genetic interactions in a quantitative trait locus. 
  • Conditional dicentric chromosomes in yeast. 
  • Conservation, duplication, and loss of the Tor signaling pathway in the fungal kingdom. 
  • Conserved cAMP signaling cascades regulate fungal development and virulence. 
  • Conserved elements of the RAM signaling pathway establish cell polarity in the basidiomycete Cryptococcus neoformans in a divergent fashion from other fungi. 
  • Conserved nucleosome positioning defines replication origins. 
  • Context dependence of meiotic recombination hotspots in yeast: the relationship between recombination activity of a reporter construct and base composition. 
  • Contribution of horizontal gene transfer to the evolution of Saccharomyces cerevisiae. 
  • Control of gene expression and assembly of chromosomal subdomains by chromatin regulators with antagonistic functions. 
  • Control of meiotic recombination and gene expression in yeast by a simple repetitive DNA sequence that excludes nucleosomes. 
  • Control of morphology and virulence by ADP-ribosylation factors (Arf) in Mucor circinelloides. 
  • Control of septin filament flexibility and bundling by subunit composition and nucleotide interactions. 
  • Control of yeast mating signal transduction by a mammalian beta 2-adrenergic receptor and Gs alpha subunit. 
  • Conversion-type and restoration-type repair of DNA mismatches formed during meiotic recombination in Saccharomyces cerevisiae. 
  • Coordinating expression of RNA binding proteins with their mRNA targets. 
  • Coping with stress: calmodulin and calcineurin in model and pathogenic fungi. 
  • Copper-chelatin: isolation from various eucaryotic sources. 
  • Cotranscriptional association of mRNA export factor Yra1 with C-terminal domain of RNA polymerase II. 
  • Creation of an active estrogen-responsive element by a single base change in the flanking sequence of a cellular oncogene: a possible mechanism for hormonal carcinogenesis? 
  • Cryo-EM structure of the essential ribosome assembly AAA-ATPase Rix7. 
  • Cryptococcus neoformans Ilv2p confers resistance to sulfometuron methyl and is required for survival at 37 degrees C and in vivo. 
  • Cryptococcus neoformans histone acetyltransferase Gcn5 regulates fungal adaptation to the host. 
  • Cryptococcus neoformans mating and virulence are regulated by the G-protein alpha subunit GPA1 and cAMP. 
  • Curated collection of yeast transcription factor DNA binding specificity data reveals novel structural and gene regulatory insights. 
  • Curing Saccharomyces cerevisiae of the 2 micron plasmid by targeted DNA damage. 
  • Cyclic AMP-dependent protein kinase catalytic subunits have divergent roles in virulence factor production in two varieties of the fungal pathogen Cryptococcus neoformans. 
  • Cyclic AMP-dependent protein kinase regulates pseudohyphal differentiation in Saccharomyces cerevisiae. 
  • Cycloheximide-resistant temperature-sensitive lethal mutations of Saccharomyces cerevisiae. 
  • Cyclophilin A and Ess1 interact with and regulate silencing by the Sin3-Rpd3 histone deacetylase. 
  • Cyclophilin A is localized to the nucleus and controls meiosis in Saccharomyces cerevisiae. 
  • Cyclophilin active site mutants have native prolyl isomerase activity with a protein substrate. 
  • Cytocidal amino acid starvation of Saccharomyces cerevisiae and Candida albicans acetolactate synthase (ilv2{Delta}) mutants is influenced by the carbon source and rapamycin. 
  • Cytokinesis breaks dicentric chromosomes preferentially at pericentromeric regions and telomere fusions. 
  • Cytological and genetic consequences for the progeny of a mitotic catastrophe provoked by Topoisomerase II deficiency. 
  • Cytosine deaminase MX cassettes as positive/negative selectable markers in Saccharomyces cerevisiae. 
  • DNA polymerase zeta introduces multiple mutations when bypassing spontaneous DNA damage in Saccharomyces cerevisiae. 
  • DNA polymerase zeta is essential for hexavalent chromium-induced mutagenesis. 
  • DNA repair mechanisms and the bypass of DNA damage in Saccharomyces cerevisiae. 
  • DNA strand-exchange patterns associated with double-strand break-induced and spontaneous mitotic crossovers in Saccharomyces cerevisiae. 
  • DNA-binding protein RAP1 stimulates meiotic recombination at the HIS4 locus in yeast. 
  • Daughter-specific transcription factors regulate cell size control in budding yeast. 
  • De Novo Heterozygous POLR2A Variants Cause a Neurodevelopmental Syndrome with Profound Infantile-Onset Hypotonia. 
  • Decoupling of nucleotide- and microtubule-binding sites in a kinesin mutant. 
  • Decreased meiotic intergenic recombination and increased meiosis I nondisjunction in exo1 mutants of Saccharomyces cerevisiae. 
  • Deletion of the Tail Domain of the Kinesin-5 Cin8 Affects Its Directionality. 
  • Deletions associated with stabilization of the Top1 cleavage complex in yeast are products of the nonhomologous end-joining pathway. 
  • Delineating the requirements for spontaneous DNA damage resistance pathways in genome maintenance and viability in Saccharomyces cerevisiae. 
  • Dependence of the regulation of telomere length on the type of subtelomeric repeat in the yeast Saccharomyces cerevisiae. 
  • Design and Analysis of Large-Scale Biological Rhythm Studies: A Comparison of Algorithms for Detecting Periodic Signals in Biological Data 
  • Destabilization of simple repetitive DNA sequences by transcription in yeast. 
  • Destabilization of yeast micro- and minisatellite DNA sequences by mutations affecting a nuclease involved in Okazaki fragment processing (rad27) and DNA polymerase delta (pol3-t). 
  • Destruction of Myc by ubiquitin-mediated proteolysis: cancer-associated and transforming mutations stabilize Myc. 
  • Detecting separate time scales in genetic expression data. 
  • Determination of mitotic recombination rates by fluctuation analysis in Saccharomyces cerevisiae. 
  • Development of Saccharomyces cerevisiae as a model pathogen. A system for the genetic identification of gene products required for survival in the mammalian host environment. 
  • Diamagnetic levitation changes growth, cell cycle, and gene expression of Saccharomyces cerevisiae. 
  • Dicentric chromosomes: unique models to study centromere function and inactivation. 
  • Differential impact of ionic and coordinate covalent chromium (Cr)-DNA binding on DNA replication. 
  • Differential localization and potency of manganese porphyrin superoxide dismutase-mimicking compounds in Saccharomyces cerevisiae. 
  • Differential regulation of transcription: repression by unactivated mitogen-activated protein kinase Kss1 requires the Dig1 and Dig2 proteins. 
  • Differential susceptibility of yeast S and M phase CDK complexes to inhibitory tyrosine phosphorylation. 
  • Direct allelic variation scanning of the yeast genome. 
  • Direct fluorescence detection of RNA on microarrays by surface-initiated enzymatic polymerization. 
  • Direct involvement of yeast type I myosins in Cdc42-dependent actin polymerization. 
  • Direct visualization of asymmetric adenine-nucleotide-induced conformational changes in MutL alpha. 
  • Directionality of individual kinesin-5 Cin8 motors is modulated by loop 8, ionic strength and microtubule geometry. 
  • Discrete in vivo roles for the MutL homologs Mlh2p and Mlh3p in the removal of frameshift intermediates in budding yeast. 
  • Dissecting the architecture of a quantitative trait locus in yeast. 
  • Distinct roles of Rho1, Cdc42, and Cyk3 in septum formation and abscission during yeast cytokinesis. 
  • Distinguishing direct versus indirect transcription factor-DNA interactions. 
  • Distribution and abundance of microsatellites in the yeast genome can Be explained by a balance between slippage events and point mutations. 
  • Double-strand breaks associated with repetitive DNA can reshape the genome. 
  • DsdA (D-serine deaminase): a new heterologous MX cassette for gene disruption and selection in Saccharomyces cerevisiae. 
  • Dual roles for DNA sequence identity and the mismatch repair system in the regulation of mitotic crossing-over in yeast. 
  • Dynamic ubiquitination of the mitogen-activated protein kinase kinase (MAPKK) Ste7 determines mitogen-activated protein kinase (MAPK) specificity. 
  • Effect of mutations in genes affecting homologous recombination on restriction enzyme-mediated and illegitimate recombination in Saccharomyces cerevisiae. 
  • Effect of sulphanilamide on formation of sterols in Saccharomyces cerevisiae and Neurospora crassa. 
  • Effects of Temperature on the Meiotic Recombination Landscape of the Yeast Saccharomyces cerevisiae. 
  • Effects of camptothecin or TOP1 overexpression on genetic stability in Saccharomyces cerevisiae. 
  • Effects of granulocyte-macrophage colony stimulating factor produced in Chinese hamster ovary cells (regramostim), Escherichia coli (molgramostim) and yeast (sargramostim) on priming peripheral blood progenitor cells for use with autologous bone marrow after high-dose chemotherapy. 
  • Effects of hexavalent chromium on the survival and cell cycle distribution of DNA repair-deficient S. cerevisiae. 
  • Effects of mismatch repair and Hpr1 on transcription-stimulated mitotic recombination in the yeast Saccharomyces cerevisiae. 
  • Effects of solid-state yeast treatment on the antioxidant properties and protein and fiber compositions of common hard wheat bran. 
  • Efficient Tor signaling requires a functional class C Vps protein complex in Saccharomyces cerevisiae. 
  • Efficient sporulation of yeast in media buffered near pH6. 
  • Electron-tunneling pathways in proteins. 
  • Elevated Genome-Wide Instability in Yeast Mutants Lacking RNase H Activity. 
  • Elucidating the Candida albicans calcineurin signaling cascade controlling stress response and virulence. 
  • Endolysosomal membrane trafficking complexes drive nutrient-dependent TORC1 signaling to control cell growth in Saccharomyces cerevisiae. 
  • Enhancement of estrogen receptor transcriptional activity by the coactivator GRIP-1 highlights the role of activation function 2 in determining estrogen receptor pharmacology. 
  • Environmental and genetic determinants of colony morphology in yeast. 
  • Enzymatically inactive p60c-src mutant with altered ATP-binding site is fully phosphorylated in its carboxy-terminal regulatory region. 
  • Enzyme redesign guided by cancer-derived IDH1 mutations. 
  • Epidemiological investigation of vaginal Saccharomyces cerevisiae isolates by a genotypic method. 
  • Estimating genomic coexpression networks using first-order conditional independence. 
  • Estrogen levels in childhood determined by an ultrasensitive recombinant cell bioassay. 
  • Evaluation of chemicals with endocrine modulating activity in a yeast-based steroid hormone receptor gene transcription assay. 
  • Evidence of mRNA-mediated intron loss in the human-pathogenic fungus Cryptococcus neoformans. 
  • Evidence that the ribosomal DNA genes of yeast are not on chromosome I. 
  • Examination of the roles of Sgs1 and Srs2 helicases in the enforcement of recombination fidelity in Saccharomyces cerevisiae. 
  • Expanding the functional repertoire of CTD kinase I and RNA polymerase II: novel phosphoCTD-associating proteins in the yeast proteome. 
  • Expansions and contractions of the genetic map relative to the physical map of yeast chromosome III. 
  • Experimental determination of rates of concerted evolution. 
  • Experimental guidance for discovering genetic networks through hypothesis reduction on time series. 
  • Expression and sequence analysis of a cDNA encoding the orotidine-5'-monophosphate decarboxylase domain from Ehrlich ascites uridylate synthase. 
  • Expression of functional bacterial undecaprenyl pyrophosphate synthase in the yeast rer2{Delta} mutant and CHO cells. 
  • Expression of functional chicken oviduct progesterone receptors in yeast (Saccharomyces cerevisiae). 
  • Expression of human protein phosphatase-1 in Saccharomyces cerevisiae highlights the role of phosphatase isoforms in regulating eukaryotic functions. 
  • Expression of human vitamin D receptor in Saccharomyces cerevisiae. Purification, properties, and generation of polyclonal antibodies. 
  • Expression of recombinant human methylmalonyl-CoA mutase: in primary mut fibroblasts and Saccharomyces cerevisiae. 
  • Expression of the Salmonella spp. virulence factor SifA in yeast alters Rho1 activity on peroxisomes. 
  • Expression profiling using microarrays fabricated by an ink-jet oligonucleotide synthesizer. 
  • FIT2 is an acyl-coenzyme A diphosphatase crucial for endoplasmic reticulum homeostasis. 
  • FK 506-binding protein proline rotamase is a target for the immunosuppressive agent FK 506 in Saccharomyces cerevisiae. 
  • FKBP12 controls aspartate pathway flux in Saccharomyces cerevisiae to prevent toxic intermediate accumulation. 
  • FKBP12 physically and functionally interacts with aspartokinase in Saccharomyces cerevisiae. 
  • FKBP12-rapamycin target TOR2 is a vacuolar protein with an associated phosphatidylinositol-4 kinase activity. 
  • Fabrication of an autoclavable one-way valve for venting fermentation gases. 
  • False-positive rate determination of protein target discovery using a covalent modification- and mass spectrometry-based proteomics platform. 
  • Farnesylation of YDJ1p is required for function at elevated growth temperatures in Saccharomyces cerevisiae. 
  • Ferrochelatase is a conserved downstream target of the blue light-sensing White collar complex in fungi. 
  • Fine-structure mapping of meiosis-specific double-strand DNA breaks at a recombination hotspot associated with an insertion of telomeric sequences upstream of the HIS4 locus in yeast. 
  • Flow cytometric analysis of DNA content in budding yeast. 
  • Formaldehyde-induced mutagenesis in Saccharomyces cerevisiae: molecular properties and the roles of repair and bypass systems. 
  • Frameshift intermediates in homopolymer runs are removed efficiently by yeast mismatch repair proteins. 
  • Frameshift mutagenesis: the roles of primer-template misalignment and the nonhomologous end-joining pathway in Saccharomyces cerevisiae. 
  • Friedreich's ataxia (GAA)n•(TTC)n repeats strongly stimulate mitotic crossovers in Saccharomyces cerevisae. 
  • From the Cover: mitotic gene conversion events induced in G1-synchronized yeast cells by gamma rays are similar to spontaneous conversion events. 
  • Function of the hydrophilic carboxyl terminus of type II DNA topoisomerase from Drosophila melanogaster. I. In vitro studies. 
  • Function of the hydrophilic carboxyl terminus of type II DNA topoisomerase from Drosophila melanogaster. II. In vivo studies. 
  • Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis. 
  • Functional expression of the multidrug resistance-associated protein in the yeast Saccharomyces cerevisiae. 
  • Functions of FKBP12 and mitochondrial cyclophilin active site residues in vitro and in vivo in Saccharomyces cerevisiae. 
  • Fungal homoserine kinase (thr1Delta) mutants are attenuated in virulence and die rapidly upon threonine starvation and serum incubation. 
  • GC content elevates mutation and recombination rates in the yeast Saccharomyces cerevisiae. 
  • GRIP: a synaptic PDZ domain-containing protein that interacts with AMPA receptors. 
  • GTPase activating specificity of RGS12 and binding specificity of an alternatively spliced PDZ (PSD-95/Dlg/ZO-1) domain. 
  • Galpha subunit Gpa2 recruits kelch repeat subunits that inhibit receptor-G protein coupling during cAMP-induced dimorphic transitions in Saccharomyces cerevisiae. 
  • Gene assembly and combinatorial libraries in S. cerevisiae via reiterative recombination. 
  • Gene conversion and crossing over along the 405-kb left arm of Saccharomyces cerevisiae chromosome VII. 
  • Gene conversion between repeated genes. 
  • Gene copy-number variation in haploid and diploid strains of the yeast Saccharomyces cerevisiae. 
  • Gene disruption with PCR products in Saccharomyces cerevisiae. 
  • Gene expression and survival changes in Saccharomyces cerevisiae during suspension culture. 
  • Genetic Analysis of Complex Traits in Saccharomyces cerevisiae . 
  • Genetic Control of Genomic Alterations Induced in Yeast by Interstitial Telomeric Sequences. 
  • Genetic analysis of a meiotic recombination hotspot on chromosome III of Saccharomyces cerevisiae. 
  • Genetic analysis of transcription-associated mutation in Saccharomyces cerevisiae. 
  • Genetic characterization of pathogenic Saccharomyces cerevisiae isolates. 
  • Genetic control of chromosome length in yeast. 
  • Genetic control of microsatellite stability. 
  • Genetic dissection of interspecific differences in yeast thermotolerance. 
  • Genetic evidence for preferential strand transfer during meiotic recombination in yeast. 
  • Genetic evidence that the meiotic recombination hotspot at the HIS4 locus of Saccharomyces cerevisiae does not represent a site for a symmetrically processed double-strand break. 
  • Genetic interactions among regulators of septin organization. 
  • Genetic manipulation of centromere function. 
  • Genetic mapping of Ty elements in Saccharomyces cerevisiae. 
  • Genetic organization, length conservation, and evolution of RNA polymerase II carboxyl-terminal domain. 
  • Genetic regulation of telomere-telomere fusions in the yeast Saccharomyces cerevisae. 
  • Genetic requirements for spontaneous and transcription-stimulated mitotic recombination in Saccharomyces cerevisiae. 
  • Genome rearrangements caused by interstitial telomeric sequences in yeast. 
  • Genome sequencing and comparative analysis of Saccharomyces cerevisiae strain YJM789. 
  • Genome structure of a Saccharomyces cerevisiae strain widely used in bioethanol production. 
  • Genome-destabilizing effects associated with top1 loss or accumulation of top1 cleavage complexes in yeast. 
  • Genome-wide analysis of genomic alterations induced by oxidative DNA damage in yeast. 
  • Genome-wide analysis of re-replication reveals inhibitory controls that target multiple stages of replication initiation. 
  • Genome-wide association analysis of clinical vs. nonclinical origin provides insights into Saccharomyces cerevisiae pathogenesis. 
  • Genome-wide chromatin footprinting reveals changes in replication origin architecture induced by pre-RC assembly. 
  • Genome-wide high-resolution mapping of UV-induced mitotic recombination events in Saccharomyces cerevisiae. 
  • Genome-wide high-resolution mapping of chromosome fragile sites in Saccharomyces cerevisiae. 
  • Genome-wide mapping of spontaneous genetic alterations in diploid yeast cells. 
  • Genomic Variation across a Clinical Cryptococcus Population Linked to Disease Outcome. 
  • Genomic characterization of POS5, the Saccharomyces cerevisiae mitochondrial NADH kinase. 
  • Genomic deletions and point mutations induced in Saccharomyces cerevisiae by the trinucleotide repeats (GAA·TTC) associated with Friedreich's ataxia. 
  • Genomic mismatch scanning: a new approach to genetic linkage mapping. 
  • Genomic regions flanking E-box binding sites influence DNA binding specificity of bHLH transcription factors through DNA shape. 
  • Genomic structure of and genome-wide recombination in the Saccharomyces cerevisiae S288C progenitor isolate EM93. 
  • Genomics: Lessons in complexity from yeast. 
  • Global analysis of genomic instability caused by DNA replication stress in Saccharomyces cerevisiae. 
  • Global analysis of the relationship between the binding of the Bas1p transcription factor and meiosis-specific double-strand DNA breaks in Saccharomyces cerevisiae. 
  • Global control of cell-cycle transcription by coupled CDK and network oscillators. 
  • Global genomic instability caused by reduced expression of DNA polymerase ε in yeast. 
  • Global mapping of meiotic recombination hotspots and coldspots in the yeast Saccharomyces cerevisiae. 
  • Glutathione reductases from a variety of sources are inhibited by physiological levels of glutathione. 
  • Grc3 programs the essential endoribonuclease Las1 for specific RNA cleavage. 
  • Guanidine hydrochloride reactivates an ancient septin hetero-oligomer assembly pathway in budding yeast. 
  • Haploidization in Saccharomyces cerevisiae induced by a deficiency in homologous recombination. 
  • Heteroduplex DNA position defines the roles of the Sgs1, Srs2, and Mph1 helicases in promoting distinct recombination outcomes. 
  • Heterogeneous polymerase fidelity and mismatch repair bias genome variation and composition. 
  • Heterologous URA3MX cassettes for gene replacement in Saccharomyces cerevisiae. 
  • High level expression of biologically active estrogen receptor in Saccharomyces cerevisiae. 
  • High rates of "unselected" aneuploidy and chromosome rearrangements in tel1 mec1 haploid yeast strains. 
  • High-Resolution Mapping of Homologous Recombination Events in rad3 Hyper-Recombination Mutants in Yeast. 
  • High-Throughput Analysis of Heteroduplex DNA in Mitotic Recombination Products. 
  • High-frequency meiotic gene conversion between repeated genes on nonhomologous chromosomes in yeast. 
  • High-resolution genome-wide analysis of irradiated (UV and γ-rays) diploid yeast cells reveals a high frequency of genomic loss of heterozygosity (LOH) events. 
  • High-resolution mapping of heteroduplex DNA formed during UV-induced and spontaneous mitotic recombination events in yeast. 
  • High-resolution mapping of spontaneous mitotic recombination hotspots on the 1.1 Mb arm of yeast chromosome IV. 
  • High-resolution mapping of two types of spontaneous mitotic gene conversion events in Saccharomyces cerevisiae. 
  • Homology analysis of the protein sequences of fatty acid synthases from chicken liver, rat mammary gland, and yeast. 
  • Homoserine toxicity in Saccharomyces cerevisiae and Candida albicans homoserine kinase (thr1Delta) mutants. 
  • Homothallic conversions of yeast mating-type genes occur by intrachromosomal recombination. 
  • Homozygous diploid deletion strains of Saccharomyces cerevisiae that determine lag phase and dehydration tolerance. 
  • Hos2p/Set3p deacetylase complex signals secretory stress through the Mpk1p cell integrity pathway. 
  • How the analysis of genetic mutations can help us to solve basic problems in gerontology? II. Life extending genetic modifications in budding yeast S. cereviseae, fruit fly D. melanogaster and laboratory mice M. musculus. 
  • Human Bcl-2 cannot directly inhibit the Caenorhabditis elegans Apaf-1 homologue CED-4, but can interact with EGL-1. 
  • Human beta-defensin 4: a novel inducible peptide with a specific salt-sensitive spectrum of antimicrobial activity. 
  • Human protein phosphatase PP6 regulatory subunits provide Sit4-dependent and rapamycin-sensitive sap function in Saccharomyces cerevisiae. 
  • INP51, a yeast inositol polyphosphate 5-phosphatase required for phosphatidylinositol 4,5-bisphosphate homeostasis and whose absence confers a cold-resistant phenotype. 
  • IP7 guards the CDK gate. 
  • Identification and characterization of a highly conserved calcineurin binding protein, CBP1/calcipressin, in Cryptococcus neoformans. 
  • Identification and characterization of a human homolog of the Schizosaccharomyces pombe ras-like gene YPT-3. 
  • Identification and characterization of an essential family of inositol polyphosphate 5-phosphatases (INP51, INP52 and INP53 gene products) in the yeast Saccharomyces cerevisiae. 
  • Identification and characterization of novel SNPs in CHEK2 in Ashkenazi Jewish men with prostate cancer. 
  • Identification and characterization of upstream open reading frames (uORF) in the 5' untranslated regions (UTR) of genes in Saccharomyces cerevisiae. 
  • Identification of 80K-H as a protein involved in GLUT4 vesicle trafficking. 
  • Identification of S-nitroso-CoA reductases that regulate protein S-nitrosylation. 
  • Identification of a Cryptococcus neoformans gene that directs expression of the cryptic Saccharomyces cerevisiae mannitol dehydrogenase gene. 
  • Identification of a distinctive mutation spectrum associated with high levels of transcription in yeast. 
  • Identification of a mutant DNA polymerase delta in Saccharomyces cerevisiae with an antimutator phenotype for frameshift mutations. 
  • Identification of a negative regulatory function for steroid receptors. 
  • Identification of a new family of protein phosphatase 2A regulatory subunits. 
  • Identification of a new subclass of Alu DNA repeats which can function as estrogen receptor-dependent transcriptional enhancers. 
  • Identification of a strand-related bias in the PCNA-mediated bypass of spontaneous lesions by yeast Poleta. 
  • Identification of a third autonomous activation domain within the human estrogen receptor. 
  • Identification of cis elements directing termination of yeast nonpolyadenylated snoRNA transcripts. 
  • Identification of novel steroid-response elements. 
  • Identification of the MATa mating-type locus of Cryptococcus neoformans reveals a serotype A MATa strain thought to have been extinct. 
  • Identification of the second chromophore of Escherichia coli and yeast DNA photolyases as 5,10-methenyltetrahydrofolate. 
  • Identification of yeast mutants with altered telomere structure. 
  • Identification, chromosomal mapping and tissue-specific expression of hREV3 encoding a putative human DNA polymerase zeta. 
  • Identification, molecular cloning, and mutagenesis of Saccharomyces cerevisiae RNA polymerase genes. 
  • Identifying phosphoCTD-associating proteins. 
  • Identifying protein phosphatase 2A interacting proteins using the yeast two-hybrid method. 
  • Immunosuppressant target protein FKBP12 is required for P-glycoprotein function in yeast. 
  • Impact of ammonium permeases mepA, mepB, and mepC on nitrogen-regulated secondary metabolism in Fusarium fujikuroi. 
  • Improved flow cytometric analysis of the budding yeast cell cycle. 
  • Improving the odorant sensitivity of olfactory receptor-expressing yeast with accessory proteins. 
  • In situ distinction between steroid receptor binding and transactivation at a target gene. 
  • In vitro reconstitution of cortical actin assembly sites in budding yeast. 
  • In vivo and in vitro examination of stability of primary hyperoxaluria-associated human alanine:glyoxylate aminotransferase. 
  • In vivo dynamics of clathrin and its adaptor-dependent recruitment to the actin-based endocytic machinery in yeast. 
  • Increased rates of genomic deletions generated by mutations in the yeast gene encoding DNA polymerase delta or by decreases in the cellular levels of DNA polymerase delta. 
  • Inferring gene expression from ribosomal promoter sequences, a crowdsourcing approach. 
  • Inositol diphosphate signaling regulates telomere length. 
  • Inositol phosphate metabolomics: merging genetic perturbation with modernized radiolabeling methods. 
  • Inositol phosphate multikinase dependent transcriptional control. 
  • Inositol pyrophosphates modulate S phase progression after pheromone-induced arrest in Saccharomyces cerevisiae. 
  • Instability of a plasmid-borne inverted repeat in Saccharomyces cerevisiae. 
  • Instability of simple sequence DNA in Saccharomyces cerevisiae. 
  • Integration of DNA fragments by illegitimate recombination in Saccharomyces cerevisiae. 
  • Interaction between transcriptional activator protein LAC9 and negative regulatory protein GAL80. 
  • Interaction of Galpha 12 and Galpha 13 with the cytoplasmic domain of cadherin provides a mechanism for beta -catenin release. 
  • Interaction of NPR1 with basic leucine zipper protein transcription factors that bind sequences required for salicylic acid induction of the PR-1 gene. 
  • Interaction of proliferating cell nuclear antigen with PMS2 is required for MutLα activation and function in mismatch repair. 
  • Interactions of TLC1 (which encodes the RNA subunit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae. 
  • Interplay between septin organization, cell cycle and cell shape in yeast. 
  • Interplay of septin amphipathic helices in sensing membrane-curvature and filament bundling. 
  • Intrachromosomal gene conversion in yeast. 
  • Introducing MX Cassettes into Saccharomyces cerevisiae. 
  • InvB is a type III secretion chaperone specific for SspA. 
  • Inverted DNA repeats channel repair of distant double-strand breaks into chromatid fusions and chromosomal rearrangements. 
  • Investigating Conservation of the Cell-Cycle-Regulated Transcriptional Program in the Fungal Pathogen, Cryptococcus neoformans. 
  • Involvement of the checkpoint protein Mec1p in silencing of gene expression at telomeres in Saccharomyces cerevisiae. 
  • Involvement of two endonuclease III homologs in the base excision repair pathway for the processing of DNA alkylation damage in Saccharomyces cerevisiae. 
  • Iron transport across biologic membranes. 
  • Is there left-handed DNA at the ends of yeast chromosomes? 
  • Isolation and analysis of recombinant DNA molecules containing yeast DNA. 
  • Isolation and biochemical characterization of LEAP-2, a novel blood peptide expressed in the liver. 
  • Isolation and characterization of a Ty element inserted into the ribosomal DNA of the yeast Saccharomyces cerevisiae. 
  • Isolation and characterization of effector-loop mutants of CDC42 in yeast. 
  • Isolation and characterization of human casein kinase I epsilon (CKI), a novel member of the CKI gene family. 
  • Isolation and characterization of point mutations in mismatch repair genes that destabilize microsatellites in yeast. 
  • Isolation of retinal proteins that interact with retinitis pigmentosa GTPase regulator by interaction trap screen in yeast. 
  • Isolation of the nuclear gene encoding a subunit of the yeast mitochondrial RNA polymerase. 
  • K63 polyubiquitination is a new modulator of the oxidative stress response. 
  • Kar3 interaction with Cik1 alters motor structure and function. 
  • Kin28, the TFIIH-associated carboxy-terminal domain kinase, facilitates the recruitment of mRNA processing machinery to RNA polymerase II. 
  • Kinesin-5 Kip1 is a bi-directional motor that stabilizes microtubules and tracks their plus-ends in vivo. 
  • Known mutator alleles do not markedly increase mutation rate in clinical Saccharomyces cerevisiae strains. 
  • LXRalpha functions as a cAMP-responsive transcriptional regulator of gene expression. 
  • Layers of regulation of cell-cycle gene expression in the budding yeast Saccharomyces cerevisiae. 
  • Length Specificity and Polymerization Mechanism of (1,3)-β-d-Glucan Synthase in Fungal Cell Wall Biosynthesis. 
  • Lic4, a nuclear phosphoprotein that cooperates with calcineurin to regulate cation homeostasis in Saccharomyces cerevisiae. 
  • Ligand-dependent and -independent function of the transactivation regions of the human estrogen receptor in yeast. 
  • Lipid rafts function in biosynthetic delivery of proteins to the cell surface in yeast. 
  • Lipid rafts in protein sorting and cell polarity in budding yeast Saccharomyces cerevisiae. 
  • Localization of RAP1 and topoisomerase II in nuclei and meiotic chromosomes of yeast. 
  • Location of the 5.8S rRNA gene of Saccharomyces cerevisiae. 
  • Long-Chain Polyprenols Promote Spore Wall Formation in Saccharomyces cerevisiae. 
  • Low levels of DNA polymerase alpha induce mitotic and meiotic instability in the ribosomal DNA gene cluster of Saccharomyces cerevisiae. 
  • MOP2 (SLA2) affects the abundance of the plasma membrane H(+)-ATPase of Saccharomyces cerevisiae. 
  • MSH6, a Saccharomyces cerevisiae protein that binds to mismatches as a heterodimer with MSH2. 
  • MX Cassettes for Knocking Out Genes in Yeast. 
  • Maf1 is an essential mediator of diverse signals that repress RNA polymerase III transcription. 
  • Manganese superoxide dismutases from Escherichia coli and from yeast mitochondria: preliminary x-ray crystallographic studies. 
  • Mapping of transcription start sites in Saccharomyces cerevisiae using 5' SAGE. 
  • Maximal polar growth potential depends on the polarisome component AgSpa2 in the filamentous fungus Ashbya gossypii. 
  • Maximal stimulation of meiotic recombination by a yeast transcription factor requires the transcription activation domain and a DNA-binding domain. 
  • Mcm2-7 Is an Active Player in the DNA Replication Checkpoint Signaling Cascade via Proposed Modulation of Its DNA Gate. 
  • Measurements of excision repair tracts formed during meiotic recombination in Saccharomyces cerevisiae. 
  • Meiosis-specific double-strand DNA breaks at the HIS4 recombination hot spot in the yeast Saccharomyces cerevisiae: control in cis and trans. 
  • Meiotic chromosome segregation in triploid strains of Saccharomyces cerevisiae. 
  • Meiotic crossing over between nonhomologous chromosomes affects chromosome segregation in yeast. 
  • Meiotic mapping of yeast ribosomal deoxyribonucleic acid on chromosome XII. 
  • Meiotic recombination between dispersed repeated genes is associated with heteroduplex formation. 
  • Meiotic recombination between repeated transposable elements in Saccharomyces cerevisiae. 
  • Meiotic recombination involving heterozygous large insertions in Saccharomyces cerevisiae: formation and repair of large, unpaired DNA loops. 
  • Meiotic recombination within the centromere of a yeast chromosome. 
  • Meiotic sister chromatid recombination. 
  • Metabolic Labeling of Inositol Phosphates and Phosphatidylinositols in Yeast and Mammalian Cells. 
  • Microsatellite analysis of genetic diversity among clinical and nonclinical Saccharomyces cerevisiae isolates suggests heterozygote advantage in clinical environments. 
  • Microsatellite instability in yeast: dependence on repeat unit size and DNA mismatch repair genes. 
  • Microsatellite instability in yeast: dependence on the length of the microsatellite. 
  • Mismatch recognition and subsequent processing have distinct effects on mitotic recombination intermediates and outcomes in yeast. 
  • Mismatch repair proteins regulate heteroduplex formation during mitotic recombination in yeast. 
  • Mitochondrial FtsZ in a chromophyte alga 
  • Mitochondrial Genome Variation Affects Multiple Respiration and Nonrespiration Phenotypes in Saccharomyces cerevisiae. 
  • Mitochondrial phosphatase PTPMT1 is essential for cardiolipin biosynthesis. 
  • Mitotic Gene Conversion Tracts Associated with Repair of a Defined Double-Strand Break in Saccharomyces cerevisiae. 
  • Mitotic and meiotic gene conversion of Ty elements and other insertions in Saccharomyces cerevisiae. 
  • Mitotic crossovers between diverged sequences are regulated by mismatch repair proteins in Saccaromyces cerevisiae. 
  • Mitotic recombination in the rDNA of S. cerevisiae is suppressed by the combined action of DNA topoisomerases I and II. 
  • Mitotic recombination in yeast: what we know and what we don't know. 
  • Mitotic recombination within the centromere of a yeast chromosome. 
  • Model systems for the study of seven-transmembrane-segment receptors. 
  • Modeling in yeast how rDNA introns slow growth and increase desiccation tolerance in lichens. 
  • Modeling mutant phenotypes and oscillatory dynamics in the \emph{Saccharomyces cerevisiae} cAMP-PKA pathway 
  • Molecular and biochemical characterization of two plant inositol polyphosphate 6-/3-/5-kinases. 
  • Molecular approaches to identify novel targets for future development of antifungal agents. 
  • Molecular characterization of the cis-prenyltransferase of Giardia lamblia. 
  • Molecular cloning of aldolases for synthetic applications. 
  • Molecular definition of a novel inositol polyphosphate metabolic pathway initiated by inositol 1,4,5-trisphosphate 3-kinase activity in Saccharomyces cerevisiae. 
  • Molecular genetics of yeast. 
  • Molecular structures of crossover and noncrossover intermediates during gap repair in yeast: implications for recombination. 
  • Most of the yeast genomic sequences are not essential for cell growth and division. 
  • Mre11-Sae2 and RPA Collaborate to Prevent Palindromic Gene Amplification. 
  • MultiFocus Polarization Microscope (MF-PolScope) for 3D polarization imaging of up to 25 focal planes simultaneously. 
  • Mutagenesis and the three R's in yeast. 
  • Mutagenesis from meiotic recombination is not a primary driver of sequence divergence between Saccharomyces species. 
  • Mutagenic effects of abasic and oxidized abasic lesions in Saccharomyces cerevisiae. 
  • Mutagenic processing of ribonucleotides in DNA by yeast topoisomerase I. 
  • Mutagenic repair of a ZFN-induced double-strand break in yeast: Effects of cleavage site sequence and spacer size. 
  • Mutation of Nogo-B receptor, a subunit of cis-prenyltransferase, causes a congenital disorder of glycosylation. 
  • Mutations in Saccharomyces cerevisiae which confer resistance to several amino acid analogs. 
  • Mutations in topoisomerase IIβ result in a B cell immunodeficiency. 
  • Mutations that perturb cyclophilin A ligand binding pocket confer cyclosporin A resistance in Saccharomyces cerevisiae. 
  • Myristoylation of calcineurin B is not required for function or interaction with immunophilin-immunosuppressant complexes in the yeast Saccharomyces cerevisiae. 
  • NADPH oxidase 4: walking the walk with Poldip2. 
  • Nanopore sequencing of complex genomic rearrangements in yeast reveals mechanisms of repeat-mediated double-strand break repair. 
  • Nascent chromatin occupancy profiling reveals locus- and factor-specific chromatin maturation dynamics behind the DNA replication fork. 
  • Natural variation in CDC28 underlies morphological phenotypes in an environmental yeast isolate. 
  • Nature and distribution of large sequence polymorphisms in Saccharomyces cerevisiae. 
  • New fungal metabolite geranylgeranyltransferase inhibitors with antifungal activity. 
  • Non-coding RNA prediction and verification in Saccharomyces cerevisiae. 
  • Noncoding Transcription Is a Driving Force for Nucleosome Instability in spt16 Mutant Cells. 
  • Nonrandom distribution of interhomolog recombination events induced by breakage of a dicentric chromosome in Saccharomyces cerevisiae. 
  • Not-so-pseudo a substrate: Acm1-mediated inhibition of the APC. 
  • Novel PMS1 alleles preferentially affect the repair of primer strand loops during DNA replication. 
  • Novel Sfp1 transcriptional regulation of Saccharomyces cerevisiae gene expression changes during spaceflight. 
  • Novel chimeric spermidine synthase-saccharopine dehydrogenase gene (SPE3-LYS9) in the human pathogen Cryptococcus neoformans. 
  • Novel estrogen response elements identified by genetic selection in yeast are differentially responsive to estrogens and antiestrogens in mammalian cells. 
  • Novel function of clathrin light chain in promoting endocytic vesicle formation. 
  • Nuclear translocation of Gln3 in response to nutrient signals requires Golgi-to-endosome trafficking in Saccharomyces cerevisiae. 
  • Nucleosomes influence multiple steps during replication initiation. 
  • Nucleotide sequence of the LYS2 gene of Saccharomyces cerevisiae: homology to Bacillus brevis tyrocidine synthetase 1. 
  • Numerous group I introns with variable distributions in the ribosomal DNA of a lichen fungus. 
  • Nutrient signaling through TOR kinases controls gene expression and cellular differentiation in fungi. 
  • Nutritional control via Tor signaling in Saccharomyces cerevisiae. 
  • O-glycosylation as a sorting determinant for cell surface delivery in yeast. 
  • Obligate sexual reproduction of a homothallic fungus closely related to the Cryptococcus pathogenic species complex. 
  • Oligonucleotide transformation of yeast reveals mismatch repair complexes to be differentially active on DNA replication strands. 
  • Organizing mRNA export. 
  • Outcrossing, mitotic recombination, and life-history trade-offs shape genome evolution in Saccharomyces cerevisiae. 
  • Overlapping specificities of base excision repair, nucleotide excision repair, recombination, and translesion synthesis pathways for DNA base damage in Saccharomyces cerevisiae. 
  • Oxidative stress survival in a clinical Saccharomyces cerevisiae isolate is influenced by a major quantitative trait nucleotide. 
  • PCR-Based Determination of Mitochondrial DNA Copy Number in Multiple Species. 
  • PINA is essential for growth and positively influences NIMA function in Aspergillus nidulans. 
  • PKC signaling regulates drug resistance of the fungal pathogen Candida albicans via circuitry comprised of Mkc1, calcineurin, and Hsp90. 
  • PR48, a novel regulatory subunit of protein phosphatase 2A, interacts with Cdc6 and modulates DNA replication in human cells. 
  • Palindromic sequences in heteroduplex DNA inhibit mismatch repair in yeast. 
  • Parallel analysis of ribonucleotide-dependent deletions produced by yeast Top1 in vitro and in vivo. 
  • Parametric modeling of cellular state transitions as measured with flow cytometry. 
  • Pathogenicity of Saccharomyces cerevisiae in complement factor five-deficient mice. 
  • Patterns of heteroduplex formation associated with the initiation of meiotic recombination in the yeast Saccharomyces cerevisiae. 
  • Phospho-carboxyl-terminal domain binding and the role of a prolyl isomerase in pre-mRNA 3'-End formation. 
  • Phospholipase C-beta 2 interacts with mitogen-activated protein kinase kinase 3. 
  • Phosphoproteome analysis in yeast. 
  • Phosphorylation of RNA polymerase II CTD fragments results in tight binding to the WW domain from the yeast prolyl isomerase Ess1. 
  • Physical detection of heteroduplexes during meiotic recombination in the yeast Saccharomyces cerevisiae. 
  • Physical lengths of meiotic and mitotic gene conversion tracts in Saccharomyces cerevisiae. 
  • Phytosphingosine as a specific inhibitor of growth and nutrient import in Saccharomyces cerevisiae. 
  • Plasma membrane polarization during mating in yeast cells. 
  • Plasma membrane proton ATPase Pma1p requires raft association for surface delivery in yeast. 
  • Pleiotropic plasma membrane ATPase mutations of Saccharomyces cerevisiae. 
  • Pleiotropic signaling pathways orchestrate yeast development. 
  • Polarity of meiotic gene conversion in fungi: contrasting views. 
  • Polarized Fluorescence Microscopy to Study Cytoskeleton Assembly and Organization in Live Cells. 
  • Polo-like kinase 1 enhances survival and mutagenesis after genotoxic stress in normal cells through cell cycle checkpoint bypass. 
  • Popping Out MX Cassettes from Saccharomyces cerevisiae. 
  • Population perspectives on functional genomic variation in yeast. 
  • Positional clustering improves computational binding site detection and identifies novel cis-regulatory sites in mammalian GABAA receptor subunit genes. 
  • Positive and negative selection LYS5MX gene replacement cassettes for use in Saccharomyces cerevisiae. 
  • Positive feedback of G1 cyclins ensures coherent cell cycle entry. 
  • Positive regulation of the vitamin D receptor by its cognate ligand in heterologous expression systems. 
  • Potentiation of progesterone receptor-mediated transcription by the immunosuppressant FK506. 
  • Predictors of Outcome in Ulcerative Colitis. 
  • Preferential synthesis of yeast mitochondrial DNA in alpha factor-arrested cells. 
  • Production of adrenergic receptors in yeast. 
  • Proline isomerases at the crossroads of protein folding, signal transduction, and immunosuppression. 
  • Prolyl isomerases in yeast. 
  • Properties of Mitotic and Meiotic Recombination in the Tandemly-Repeated CUP1 Gene Cluster in the Yeast Saccharomyces cerevisiae. 
  • Protection against Experimental Cryptococcosis following Vaccination with Glucan Particles Containing Cryptococcus Alkaline Extracts. 
  • Protection from nitrosative stress by yeast flavohemoglobin. 
  • Protein kinase A operates a molecular switch that governs yeast pseudohyphal differentiation. 
  • Protein kinase activity of Tel1p and Mec1p, two Saccharomyces cerevisiae proteins related to the human ATM protein kinase. 
  • Protein prenyltransferases. 
  • Proteome-wide search reveals unexpected RNA-binding proteins in Saccharomyces cerevisiae. 
  • R73A and H144Q mutants of the yeast mitochondrial cyclophilin Cpr3 exhibit a low prolyl isomerase activity in both peptide and protein-folding assays. 
  • RNAi function, diversity, and loss in the fungal kingdom. 
  • RNA∶DNA hybrids initiate quasi-palindrome-associated mutations in highly transcribed yeast DNA. 
  • Rapamycin and less immunosuppressive analogs are toxic to Candida albicans and Cryptococcus neoformans via FKBP12-dependent inhibition of TOR. 
  • Rapamycin antifungal action is mediated via conserved complexes with FKBP12 and TOR kinase homologs in Cryptococcus neoformans. 
  • Rapamycin exerts antifungal activity in vitro and in vivo against Mucor circinelloides via FKBP12-dependent inhibition of Tor. 
  • Rapamycin induces the G0 program of transcriptional repression in yeast by interfering with the TOR signaling pathway. 
  • Rapid and quantitative imaging of excitation polarized fluorescence reveals ordered septin dynamics in live yeast. 
  • Rapid generation of potent antibodies by autonomous hypermutation in yeast. 
  • Rapid purification of microtubule motor domain proteins expressed in bacteria. 
  • Ratiometric GPCR signaling enables directional sensing in yeast. 
  • Rational design of superoxide dismutase (SOD) mimics: the evaluation of the therapeutic potential of new cationic Mn porphyrins with linear and cyclic substituents. 
  • Reciprocal uniparental disomy in yeast. 
  • Recombination between genes located on nonhomologous chromosomes in Saccharomyces cerevisiae. 
  • Recombination between homologous chromosomes induced by unrepaired UV-generated DNA damage requires Mus81p and is suppressed by Mms2p. 
  • Recombination between retrotransposons as a source of chromosome rearrangements in the yeast Saccharomyces cerevisiae. 
  • Recombination in yeast and the recombinant DNA technology. 
  • Recombination of plasmids into the Saccharomyces cerevisiae chromosome is reduced by small amounts of sequence heterogeneity. 
  • Recombinational Repair of Nuclease-Generated Mitotic Double-Strand Breaks with Different End Structures in Yeast. 
  • Reconciling conflicting models for global control of cell-cycle transcription. 
  • Reconstitution of the vitamin D-responsive osteocalcin transcription unit in Saccharomyces cerevisiae. 
  • Reconstructing the temporal ordering of biological samples using microarray data. 
  • Reduced levels of DNA polymerase delta induce chromosome fragile site instability in yeast. 
  • Reduction of invasive bacteria in ethanol fermentations using bacteriophages. 
  • Reg1p targets protein phosphatase 1 to dephosphorylate hexokinase II in Saccharomyces cerevisiae: characterizing the effects of a phosphatase subunit on the yeast proteome. 
  • Regional bivalent-univalent pairing versus trivalent pairing of a trisomic chromosome in Saccharomyces cerevisiae. 
  • Regulation of ALK-1 signaling by the nuclear receptor LXRbeta. 
  • Regulation of a cyclin-CDK-CDK inhibitor complex by inositol pyrophosphates. 
  • Regulation of genome stability by TEL1 and MEC1, yeast homologs of the mammalian ATM and ATR genes. 
  • Regulation of hetDNA Length during Mitotic Double-Strand Break Repair in Yeast. 
  • Regulation of mitotic homeologous recombination in yeast. Functions of mismatch repair and nucleotide excision repair genes. 
  • Regulation of phosphatidate phosphatase activity from the yeast Saccharomyces cerevisiae by sphingoid bases. 
  • Regulation of topoisomerase II by phosphorylation: a role for casein kinase II. 
  • Regulators of pseudohyphal differentiation in Saccharomyces cerevisiae identified through multicopy suppressor analysis in ammonium permease mutant strains. 
  • Regulatory interactions between the Reg1-Glc7 protein phosphatase and the Snf1 protein kinase. 
  • Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii. 
  • Reiterative Recombination for the in vivo assembly of libraries of multigene pathways. 
  • Relationship between nuclease-hypersensitive sites and meiotic recombination hot spot activity at the HIS4 locus of Saccharomyces cerevisiae. 
  • Relationship between the G protein signaling and homologous desensitization of G protein-coupled receptors. 
  • Release of ubiquitin-charged Cdc34-S - Ub from the RING domain is essential for ubiquitination of the SCF(Cdc4)-bound substrate Sic1. 
  • Removal of N-6-methyladenine by the nucleotide excision repair pathway triggers the repair of mismatches in yeast gap-repair intermediates. 
  • Removal of frameshift intermediates by mismatch repair proteins in Saccharomyces cerevisiae. 
  • Repair of DNA loops involves DNA-mismatch and nucleotide-excision repair proteins. 
  • Repair of specific base pair mismatches formed during meiotic recombination in the yeast Saccharomyces cerevisiae. 
  • Replicating circular DNA molecules in yeast. 
  • Replication and preferential inheritance of hypersuppressive petite mitochondrial DNA. 
  • Replication of yeast chromosomal DNA. 
  • Repression of yeast Ste12 transcription factor by direct binding of unphosphorylated Kss1 MAPK and its regulation by the Ste7 MEK. 
  • Ribodysgenesis: sudden genome instability in the yeast Saccharomyces cerevisiae arising from RNase H2 cleavage at genomic-embedded ribonucleotides. 
  • Ribonomic analysis of human Pum1 reveals cis-trans conservation across species despite evolution of diverse mRNA target sets. 
  • Ribonucleotides and Transcription-Associated Mutagenesis in Yeast. 
  • Ribotrap : targeted purification of RNA-specific RNPs from cell lysates through immunoaffinity precipitation to identify regulatory proteins and RNAs. 
  • RoboCOP: jointly computing chromatin occupancy profiles for numerous factors from chromatin accessibility data. 
  • Role for topoisomerase 1 in transcription-associated mutagenesis in yeast. 
  • Role of Cdc42p in pheromone-stimulated signal transduction in Saccharomyces cerevisiae. 
  • Role of Inn1 and its interactions with Hof1 and Cyk3 in promoting cleavage furrow and septum formation in S. cerevisiae. 
  • Role of Scd5, a protein phosphatase-1 targeting protein, in phosphoregulation of Sla1 during endocytosis. 
  • Role of arginine 180 and glutamic acid 177 of ricin toxin A chain in enzymatic inactivation of ribosomes. 
  • Role of mismatch repair in the fidelity of RAD51- and RAD59-dependent recombination in Saccharomyces cerevisiae. 
  • Role of nitrogen and carbon transport, regulation, and metabolism genes for Saccharomyces cerevisiae survival in vivo. 
  • Role of proliferating cell nuclear antigen interactions in the mismatch repair-dependent processing of mitotic and meiotic recombination intermediates in yeast. 
  • Role of the Hof1-Cyk3 interaction in cleavage-furrow ingression and primary-septum formation during yeast cytokinesis. 
  • Role of the Srs2-Rad51 Interaction Domain in Crossover Control in Saccharomyces cerevisiae. 
  • Roles of exonucleases and translesion synthesis DNA polymerases during mitotic gap repair in yeast. 
  • Roles of inositol phosphates and inositol pyrophosphates in development, cell signaling and nuclear processes. 
  • Rsp5 ubiquitin-protein ligase mediates DNA damage-induced degradation of the large subunit of RNA polymerase II in Saccharomyces cerevisiae. 
  • Rvs161p and sphingolipids are required for actin repolarization following salt stress. 
  • SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatases. 
  • SCF E3-mediated autoubiquitination negatively regulates activity of Cdc34 E2 but plays a nonessential role in the catalytic cycle in vitro and in vivo. 
  • SRD5A3 is required for converting polyprenol to dolichol and is mutated in a congenital glycosylation disorder. 
  • STT4 is an essential phosphatidylinositol 4-kinase that is a target of wortmannin in Saccharomyces cerevisiae. 
  • SW1PerS: Sliding windows and 1-persistence scoring; discovering periodicity in gene expression time series data. 
  • Saccharomyces cerevisiae Bzz1p is implicated with type I myosins in actin patch polarization and is able to recruit actin-polymerizing machinery in vitro. 
  • Saccharomyces cerevisiae MutLalpha is a mismatch repair endonuclease. 
  • Saccharomyces cerevisiae Ntg1p and Ntg2p: broad specificity N-glycosylases for the repair of oxidative DNA damage in the nucleus and mitochondria. 
  • Saccharomyces cerevisiae gene expression changes during rotating wall vessel suspension culture. 
  • Saccharomyces cerevisiae vacuole in zinc storage and intracellular zinc distribution. 
  • Saccharomyces cerevisiae virulence phenotype as determined with CD-1 mice is associated with the ability to grow at 42 degrees C and form pseudohyphae. 
  • Saccharomyces cerevisiae: population divergence and resistance to oxidative stress in clinical, domesticated and wild isolates. 
  • Scaffold-mediated symmetry breaking by Cdc42p. 
  • Scd5p and clathrin function are important for cortical actin organization, endocytosis, and localization of sla2p in yeast. 
  • Schizosaccharomyces pombe Sst4p, a conserved Vps27/Hrs homolog, functions downstream of phosphatidylinositol 3-kinase Pik3p to mediate proper spore formation. 
  • Secretion of FK506/FK520 and rapamycin by Streptomyces inhibits the growth of competing Saccharomyces cerevisiae and Cryptococcus neoformans. 
  • Sedimentation properties of yeast chromosomal DNA. 
  • Segregation of recombinant chromatids following mitotic crossing over in yeast. 
  • Selection and analysis of spontaneous reciprocal mitotic cross-overs in Saccharomyces cerevisiae. 
  • Selection of novel affinity-matured human chondroitin sulfate proteoglycan 4 antibody fragments by yeast display. 
  • Separation of chromosomes of Cryptococcus neoformans by pulsed field gel electrophoresis. 
  • Septin assemblies form by diffusion-driven annealing on membranes. 
  • Septin complexes assemble during a kinetic window of opportunity. 
  • Septin ring assembly involves cycles of GTP loading and hydrolysis by Cdc42p. 
  • Sequence composition and context effects on the generation and repair of frameshift intermediates in mononucleotide runs in Saccharomyces cerevisiae. 
  • Sequence divergence impedes crossover more than noncrossover events during mitotic gap repair in yeast. 
  • Sequences within a small yeast RNA required for inhibition of internal initiation of translation: interaction with La and other cellular proteins influences its inhibitory activity. 
  • Sequences within the spacer region of yeast rRNA cistrons that stimulate 35S rRNA synthesis in vivo mediate RNA polymerase I-dependent promoter and terminator activities. 
  • Sequential elimination of major-effect contributors identifies additional quantitative trait loci conditioning high-temperature growth in yeast. 
  • Seven-base-pair inverted repeats in DNA form stable hairpins in vivo in Saccharomyces cerevisiae. 
  • Seven-up inhibits ultraspiracle-based signaling pathways in vitro and in vivo. 
  • Shared genetic pathways contribute to the tolerance of endogenous and low-dose exogenous DNA damage in yeast. 
  • Shuffling the yeast genome using CRISPR/Cas9-generated DSBs that target the transposable Ty1 elements. 
  • Signal transduction cascades regulating pseudohyphal differentiation of Saccharomyces cerevisiae. 
  • Signal transduction. Unexpected mediators of protein phosphorylation. 
  • Simple Mendelian inheritance of the reiterated ribosomal DNA of yeast. 
  • Simple Mendelian inheritance of the repeating yeast ribosomal DNA genes. 
  • Singularity in polarization: rewiring yeast cells to make two buds. 
  • Sir2 suppresses transcription-mediated displacement of Mcm2-7 replicative helicases at the ribosomal DNA repeats. 
  • Sirtuin 5 Is Regulated by the SCFCyclin F Ubiquitin Ligase and Is Involved in Cell Cycle Control. 
  • Size and structure of yeast chromosomal DNA. 
  • Sok2 regulates yeast pseudohyphal differentiation via a transcription factor cascade that regulates cell-cell adhesion. 
  • Spatial guidance of cell asymmetry: septin GTPases show the way. 
  • Species and genotypic diversities and similarities of pathogenic yeasts colonizing women. 
  • Species identification and virulence attributes of Saccharomyces boulardii (nom. inval.). 
  • Sphingolipids signal heat stress-induced ubiquitin-dependent proteolysis. 
  • Split luciferase complementation assay for the analysis of G protein-coupled receptor ligand response in Saccharomyces cerevisiae. 
  • Spontaneous deamination of cytosine to uracil is biased to the non-transcribed DNA strand in yeast. 
  • Spontaneous frameshift mutations in Saccharomyces cerevisiae: accumulation during DNA replication and removal by proofreading and mismatch repair activities. 
  • Stabilization of microsatellite sequences by variant repeats in the yeast Saccharomyces cerevisiae. 
  • StableIsotope Labeling with Amino Acids in Cell Culture (SILAC)-based strategy for proteome-wide thermodynamic analysis of protein-ligand binding interactions. 
  • Steady state kinetic studies of purified yeast plasma membrane proton-translocating ATPase. 
  • Structural analysis and detection of biological inositol pyrophosphates reveal that the family of VIP/diphosphoinositol pentakisphosphate kinases are 1/3-kinases. 
  • Structural analysis of a yeast centromere. 
  • Structural impact of K63 ubiquitin on yeast translocating ribosomes under oxidative stress. 
  • Structural relationships in glycogen phosphorylases. 
  • Structural requirements for high affinity ligand binding by estrogen receptors: a comparative analysis of truncated and full length estrogen receptors expressed in bacteria, yeast, and mammalian cells. 
  • Structural studies and protein engineering of inositol phosphate multikinase. 
  • Structure of DNA in DNA replication mutants of yeast. 
  • Structure of the Rad50 x Mre11 DNA repair complex from Saccharomyces cerevisiae by electron microscopy. 
  • Structures of naturally evolved CUP1 tandem arrays in yeast indicate that these arrays are generated by unequal nonhomologous recombination. 
  • Structures of yeast vesicle trafficking proteins. 
  • Studies of the phosphoenzyme intermediate of the yeast plasma membrane proton-translocating ATPase. 
  • Study of the kinetic and physical properties of the orotidine-5'-monophosphate decarboxylase domain from mouse UMP synthase produced in Saccharomyces cerevisiae. 
  • Substrate length requirements for efficient mitotic recombination in Saccharomyces cerevisiae. 
  • Suppressor analysis of temperature-sensitive RNA polymerase I mutations in Saccharomyces cerevisiae: suppression of mutations in a zinc-binding motif by transposed mutant genes. 
  • Syndrome of hepatic cirrhosis, dystonia, polycythemia, and hypermanganesemia caused by mutations in SLC30A10, a manganese transporter in man. 
  • Synthetic biology: Division of logic labour. 
  • System for expression of microsporidian methionine amino peptidase type 2 (MetAP2) in the yeast Saccharomyces cerevisiae. 
  • Systematic analysis of F-box proteins reveals a new branch of the yeast mating pathway. 
  • TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene. 
  • TOR controls transcriptional and translational programs via Sap-Sit4 protein phosphatase signaling effectors. 
  • TOR kinase homologs function in a signal transduction pathway that is conserved from yeast to mammals. 
  • TOR mutations confer rapamycin resistance by preventing interaction with FKBP12-rapamycin. 
  • Tandemly arranged variant 5S ribosomal RNA genes in the yeast Saccharomyces cerevisiae. 
  • Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast. 
  • Targets of immunophilin-immunosuppressant complexes are distinct highly conserved regions of calcineurin A. 
  • Tetramerization and single-stranded DNA binding properties of native and mutated forms of murine mitochondrial single-stranded DNA-binding proteins. 
  • The 100-genomes strains, an S. cerevisiae resource that illuminates its natural phenotypic and genotypic variation and emergence as an opportunistic pathogen. 
  • The 2013 Thomas Hunt Morgan Medal: Thomas Douglas Petes. 
  • The 9-1-1 checkpoint clamp physically interacts with polzeta and is partially required for spontaneous polzeta-dependent mutagenesis in Saccharomyces cerevisiae. 
  • The ATP binding site of the yeast plasma membrane proton-translocating ATPase. 
  • The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces cerevisiae genome. 
  • The Caenorhabditis elegans CED-9 protein does not directly inhibit the caspase CED-3, in vitro nor in yeast. 
  • The Cryptococcus neoformans Flc1 Homologue Controls Calcium Homeostasis and Confers Fungal Pathogenicity in the Infected Hosts. 
  • The DNA helicase activities of Rad3 protein of Saccharomyces cerevisiae and helicase II of Escherichia coli are differentially inhibited by covalent and noncovalent DNA modifications. 
  • The DNA-binding protein Hdf1p (a putative Ku homologue) is required for maintaining normal telomere length in Saccharomyces cerevisiae. 
  • The Ess1 prolyl isomerase is linked to chromatin remodeling complexes and the general transcription machinery. 
  • The G protein-coupled receptor gpr1 is a nutrient sensor that regulates pseudohyphal differentiation in Saccharomyces cerevisiae. 
  • The Galpha protein Gpa2 controls yeast differentiation by interacting with kelch repeat proteins that mimic Gbeta subunits. 
  • The Local Edge Machine: inference of dynamic models of gene regulation. 
  • The MEP2 ammonium permease regulates pseudohyphal differentiation in Saccharomyces cerevisiae. 
  • The Mre11p/Rad50p/Xrs2p complex and the Tel1p function in a single pathway for telomere maintenance in yeast. 
  • The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins. 
  • The RNA polymerase II CTD kinase CTDK-I affects pre-mRNA 3' cleavage/polyadenylation through the processing component Pti1p. 
  • The RNase P associated with HeLa cell mitochondria contains an essential RNA component identical in sequence to that of the nuclear RNase P. 
  • The SV40 core sequence functions as a repressor element in yeast. 
  • The Saccharomyces and Drosophila heat shock transcription factors are identical in size and DNA binding properties. 
  • The Saccharomyces cerevisiae suppressor of choline sensitivity (SCS2) gene is a multicopy Suppressor of mec1 telomeric silencing defects. 
  • The TOR signal transduction cascade controls cellular differentiation in response to nutrients. 
  • The TOR signaling cascade regulates gene expression in response to nutrients. 
  • The Tn3 beta-lactamase gene acts as a hotspot for meiotic recombination in yeast. 
  • The Transient Inactivation of the Master Cell Cycle Phosphatase Cdc14 Causes Genomic Instability in Diploid Cells of Saccharomyces cerevisiae. 
  • The beta2-adrenergic receptor/betaarrestin complex recruits the clathrin adaptor AP-2 during endocytosis. 
  • The catalytic subunit of yeast telomerase. 
  • The cell-cycle transcriptional network generates and transmits a pulse of transcription once each cell cycle. 
  • The compact chromatin structure of a Ty repeated sequence suppresses recombination hotspot activity in Saccharomyces cerevisiae. 
  • The composition and morphology of yeast nuclear scaffolds. 
  • The conserved bromo-adjacent homology domain of yeast Orc1 functions in the selection of DNA replication origins within chromatin. 
  • The dCMP transferase activity of yeast Rev1 is biologically relevant during the bypass of endogenously generated AP sites. 
  • The deacetylase Sir2 from the yeast Clavispora lusitaniae lacks the evolutionarily conserved capacity to generate subtelomeric heterochromatin. 
  • The effect of oxidative metabolism on spontaneous Pol zeta-dependent translesion synthesis in Saccharomyces cerevisiae. 
  • The effect of sequence context on spontaneous Polzeta-dependent mutagenesis in Saccharomyces cerevisiae. 
  • The effects of molecular noise and size control on variability in the budding yeast cell cycle. 
  • The essential sequence elements required for RNAP II carboxyl-terminal domain function in yeast and their evolutionary conservation. 
  • The exoribonuclease Xrn1 is a post-transcriptional negative regulator of autophagy. 
  • The family of glycogen phosphorylases: structure and function. 
  • The fidelity of DNA replication, particularly on GC-rich templates, is reduced by defects of the Fe-S cluster in DNA polymerase δ. 
  • The genetic architecture of biofilm formation in a clinical isolate of Saccharomyces cerevisiae. 
  • The high mobility group protein Abf2p influences the level of yeast mitochondrial DNA recombination intermediates in vivo. 
  • The histone methylase Set2p and the histone deacetylase Rpd3p repress meiotic recombination at the HIS4 meiotic recombination hotspot in Saccharomyces cerevisiae. 
  • The immunosuppressant FK506 inhibits amino acid import in Saccharomyces cerevisiae. 
  • The in vivo characterization of translesion synthesis across UV-induced lesions in Saccharomyces cerevisiae: insights into Pol zeta- and Pol eta-dependent frameshift mutagenesis. 
  • The inhibitor-1 C terminus facilitates hormonal regulation of cellular protein phosphatase-1: functional implications for inhibitor-1 isoforms. 
  • The kelch proteins Gpb1 and Gpb2 inhibit Ras activity via association with the yeast RasGAP neurofibromin homologs Ira1 and Ira2. 
  • The mammalian Rad24 homologous to yeast Saccharomyces cerevisiae Rad24 and Schizosaccharomyces pombe Rad17 is involved in DNA damage checkpoint. 
  • The mechanism of nucleotide excision repair-mediated UV-induced mutagenesis in nonproliferating cells. 
  • The mismatch repair system promotes DNA polymerase zeta-dependent translesion synthesis in yeast. 
  • The network and the remodeling theories of aging: historical background and new perspectives. 
  • The nucleotide sequence of Saccharomyces cerevisiae chromosome IV. 
  • The nucleotide sequence of Saccharomyces cerevisiae chromosome V. 
  • The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI. 
  • The numbers of individual mitochondrial DNA molecules and mitochondrial DNA nucleoids in yeast are co-regulated by the general amino acid control pathway. 
  • The p35 relative, p49, inhibits mammalian and Drosophila caspases including DRONC and protects against apoptosis. 
  • The pattern of gene amplification is determined by the chromosomal location of hairpin-capped breaks. 
  • The polymerase eta translesion synthesis DNA polymerase acts independently of the mismatch repair system to limit mutagenesis caused by 7,8-dihydro-8-oxoguanine in yeast. 
  • The quick and the dead: microbial demography at the yeast thermal limit. 
  • The rRNA-encoding DNA array has an altered structure in topoisomerase I mutants of Saccharomyces cerevisiae. 
  • The reacquisition of biotin prototrophy in Saccharomyces cerevisiae involved horizontal gene transfer, gene duplication and gene clustering. 
  • The reference genome sequence of Saccharomyces cerevisiae: then and now. 
  • The regulation of DNA topoisomerase II by casein kinase II. 
  • The role of Aspartyl aminopeptidase (Ape4) in Cryptococcus neoformans virulence and authophagy. 
  • The role of Dbf4-dependent protein kinase in DNA polymerase ζ-dependent mutagenesis in Saccharomyces cerevisiae. 
  • The role of Exo1p exonuclease in DNA end resection to generate gene conversion tracts in Saccharomyces cerevisiae. 
  • The role of the mismatch repair machinery in regulating mitotic and meiotic recombination between diverged sequences in yeast. 
  • The roles of telomeres and telomerase in cell life span. 
  • The secretory pathway in control of endoplasmic reticulum homeostasis. 
  • The septin cortex at the yeast mother-bud neck. 
  • The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present. 
  • The statistics of bulk segregant analysis using next generation sequencing. 
  • The structure of a primitive kinetochore. 
  • The suppressor gene scl1+ of Saccharomyces cerevisiae is essential for growth. 
  • The tRNA-Tyr gene family of Saccharomyces cerevisiae: agents of phenotypic variation and position effects on mutation frequency. 
  • The tor pathway regulates gene expression by linking nutrient sensing to histone acetylation. 
  • The unusual UBZ domain of Saccharomyces cerevisiae polymerase η. 
  • The use of proline as a nitrogen source causes hypersensitivity to, and allows more economical use of 5FOA in Saccharomyces cerevisiae. 
  • The yeast HSM3 gene is not involved in DNA mismatch repair in rapidly dividing cells. 
  • The yeast Rab GTPase Ypt1 modulates unfolded protein response dynamics by regulating the stability of HAC1 RNA. 
  • The yeast carboxyl-terminal repeat domain kinase CTDK-I is a divergent cyclin-cyclin-dependent kinase complex. 
  • Three galactose inducible promoters for use in C. neoformans var. grubii. 
  • Three new dominant drug resistance cassettes for gene disruption in Saccharomyces cerevisiae. 
  • Time-dependent mitotic recombination in Saccharomyces cerevisiae. 
  • Timely Endocytosis of Cytokinetic Enzymes Prevents Premature Spindle Breakage during Mitotic Exit. 
  • Topoisomerase I and Genome Stability: The Good and the Bad. 
  • Topoisomerase I plays a critical role in suppressing genome instability at a highly transcribed G-quadruplex-forming sequence. 
  • Topology and control of the cell-cycle-regulated transcriptional circuitry. 
  • Topology of the yeast plasma membrane proton-translocating ATPase. 
  • Total Synthesis of a Functional Designer Eukaryotic Chromosome 
  • Total reconstitution of copper-zinc superoxide dismutase. 
  • Transactivation functions facilitate the disruption of chromatin structure by estrogen receptor derivatives in vivo. 
  • Transcription Factor-DNA Binding Motifs in Saccharomyces cerevisiae: Tools and Resources. 
  • Transcription errors induce proteotoxic stress and shorten cellular lifespan. 
  • Transcription factors are required for the meiotic recombination hotspot at the HIS4 locus in Saccharomyces cerevisiae. 
  • Transcription-associated mutagenesis in yeast is directly proportional to the level of gene expression and influenced by the direction of DNA replication. 
  • Transcriptional regulation improves the throughput of three-hybrid counter selections in Saccharomyces cerevisiae. 
  • Transcriptional regulation of changes in growth, cell cycle, and gene expression of Saccharomyces cerevisiae due to changes in buoyancy. 
  • Transfer of the Septin Ring to Cytokinetic Remnants in ER Stress Directs Age-Sensitive Cell-Cycle Re-entry. 
  • Transformation of Saccharomyces cerevisiae with nonhomologous DNA: illegitimate integration of transforming DNA into yeast chromosomes and in vivo ligation of transforming DNA to mitochondrial DNA sequences. 
  • Transposed LEU2 gene of Saccharomyces cerevisiae is regulated normally. 
  • Triplet repeats form secondary structures that escape DNA repair in yeast. 
  • Two distinct genes encode small isoproteolipids affecting plasma membrane H(+)-ATPase activity of Saccharomyces cerevisiae. 
  • Two distinct mechanisms of Topoisomerase 1-dependent mutagenesis in yeast. 
  • Type I and type II keratins have evolved from lower eukaryotes to form the epidermal intermediate filaments in mammalian skin. 
  • Unconventional ubiquitin recognition by the ubiquitin-binding motif within the Y family DNA polymerases iota and Rev1. 
  • Unequal meiotic recombination within tandem arrays of yeast ribosomal DNA genes. 
  • Unified nomenclature for subunits of the Saccharomyces cerevisiae proteasome regulatory particle. 
  • Unraveling the Mechanical Unfolding Pathways of a Multidomain Protein: Phosphoglycerate Kinase. 
  • Unusual DNA sequences associated with the ends of yeast chromosomes. 
  • Using extremal events to characterize noisy time series. 
  • Using graphical models and genomic expression data to statistically validate models of genetic regulatory networks. 
  • Variation in efficiency of DNA mismatch repair at different sites in the yeast genome. 
  • Verification of a new gene on Saccharomyces cerevisiae chromosome III. 
  • Vesicular Trafficking Systems Impact TORC1-Controlled Transcriptional Programs in Saccharomyces cerevisiae. 
  • Vip1 is a kinase and pyrophosphatase switch that regulates inositol diphosphate signaling. 
  • Water permeability of aquaporin-4 channel depends on bilayer composition, thickness, and elasticity. 
  • When sensing is gambling: An experimental system reveals how plasticity can generate tunable bet-hedging strategies. 
  • When two is better than one. 
  • Whole Recombinant Saccharomyces cerevisiae Yeast Expressing Ras Mutations as Treatment for Patients With Solid Tumors Bearing Ras Mutations: Results From a Phase 1 Trial. 
  • Whole genome genetic-typing in yeast using high-density oligonucleotide arrays. 
  • Whole-genome comparison of Leu3 binding in vitro and in vivo reveals the importance of nucleosome occupancy in target site selection. 
  • X-ray crystal structure of the yeast Kar3 motor domain complexed with Mg.ADP to 2.3 A resolution. 
  • Yeast Cdc42 functions at a late step in exocytosis, specifically during polarized growth of the emerging bud. 
  • Yeast RPO41 gene product is required for transcription and maintenance of the mitochondrial genome. 
  • Yeast RSP5 and its human homolog hRPF1 potentiate hormone-dependent activation of transcription by human progesterone and glucocorticoid receptors. 
  • Yeast base excision repair: interconnections and networks. 
  • Yeast chromosomal DNA: size, structure, and replication. 
  • Yeast microarrays for genome wide parallel genetic and gene expression analysis. 
  • Yeast pseudohyphal growth is regulated by GPA2, a G protein alpha homolog. 
  • Yeast ribosomal DNA genes are located on chromosome XII. 
  • beta 1-adrenergic receptor association with PSD-95. Inhibition of receptor internalization and facilitation of beta 1-adrenergic receptor interaction with N-methyl-D-aspartate receptors. 
  • cDNA cloning and expression of rat and human protein geranylgeranyltransferase type-I. 
  • cis element/transcription factor analysis (cis/TF): a method for discovering transcription factor/cis element relationships. 
  • crl mutants of Saccharomyces cerevisiae resemble both mutants affecting general control of amino acid biosynthesis and omnipotent translational suppressor mutants. 
  • dUTP incorporation into genomic DNA is linked to transcription in yeast. 
  • pYAC-RC, a yeast artificial chromosome vector for cloning DNA cut with infrequently cutting restriction endonucleases. 
  • vph6 mutants of Saccharomyces cerevisiae require calcineurin for growth and are defective in vacuolar H(+)-ATPase assembly. 
• 

  Keywords of People

  • Carbrey, Jennifer Mehlman, Assistant Research Professor of Cell Biology, Cell Biology
  • Gordan, Raluca Mihaela, Associate Professor in Biostatistics & Bioinformatics, Computer Science
  • Hartemink, Alexander J., Professor in the Department of Computer Science, Biology
  • McDonnell, Donald Patrick, Glaxo-Wellcome Distinguished Professor of Molecular Cancer Biology, in the School of Medicine, Cell Biology
  • Sampson, John Howard, Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine, Biomedical Engineering
  • Taylor, Gregory Alan, Professor in Medicine, Integrative Immunobiology
  • Wray, Gregory Allan, Professor of Biology, Evolutionary Anthropology