Osteosarcoma

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  Subject Areas on Research

  • 5-Fluorouracil in childhood solid tumors. 
  • A novel, non-apoptotic role for Scythe/BAT3: a functional switch between the pro- and anti-proliferative roles of p21 during the cell cycle. 
  • A perioperative strategy for the placement of a thoracic epidural catheter in a pediatric patient on high-dose enoxaprin. 
  • ASO Visual Abstract: Identifying Modifiable and Non-Modifiable Risk Factors of Readmission and Short-Term Mortality in Osteosarcoma-A National Cancer Database Study. 
  • Abundant tyrosine residues in the antigen binding site in anti-osteosarcoma monoclonal antibodies TP-1 and TP-3: Application to radiolabeling. 
  • Adjuvant chemotherapy for osteosarcoma may not increase survival after neoadjuvant chemotherapy and surgical resection. 
  • Adjuvant chemotherapy for osteosarcoma of the extremity. Long-term results of two consecutive prospective protocol studies. 
  • Adjuvant chemotherapy in nonmetastatic osteosarcoma: a Southwest Oncology Group Study. 
  • Adjuvant chemotherapy in primary treatment of osteogenic sarcoma. A Southwest Oncology Group study. 
  • Adverse hypersensitivity reactions to mesna as adjunctive therapy for cyclophosphamide. 
  • An evolutionary framework for treating pediatric sarcomas. 
  • An exploratory study of environmental and medical factors potentially related to childhood cancer. 
  • Autopsy and grief: a case of transformative postmortem examination. 
  • BMP-2 inhibits tumor-initiating ability in human renal cancer stem cells and induces bone formation. 
  • Beta4 integrin promotes osteosarcoma metastasis and interacts with ezrin. 
  • Bone Morphogenetic Proteins Are Expressed by Both Bone-Forming and Non-Bone-Forming Lesions. 
  • Bone formation induced by BMP-2 in human osteosarcoma cells. 
  • Can you tBID on it? 
  • Clinical and morphologic features of post-traumatic ocular sarcomas in cats. 
  • Cloning and sequencing of V genes from anti-osteosarcoma monoclonal antibodies TP-1 and TP-3: location of lysine residues and implications for radiolabeling. 
  • Combination chemotherapy for osteosarcoma. 
  • Common genetic variants associated with telomere length confer risk for neuroblastoma and other childhood cancers. 
  • Common genetic variation and risk of osteosarcoma in a multi-ethnic pediatric and adolescent population. 
  • Cowpox virus and other members of the orthopoxvirus genus interfere with the regulation of NF-kappaB activation. 
  • Cowpox virus encodes a fifth member of the tumor necrosis factor receptor family: a soluble, secreted CD30 homologue. 
  • Custom facial reconstruction for osteosarcoma of the jaw. 
  • Cytoplasmic and/or nuclear accumulation of the beta-catenin protein is a frequent event in human osteosarcoma. 
  • Deletions and point mutations of p16,p15 gene in primary tumors and tumor cell lines. 
  • Deletions of a DNA sequence in retinoblastomas and mesenchymal tumors: organization of the sequence and its encoded protein. 
  • Electrophoretic evaluation of sera from dogs with cancer. 
  • Endogenous protein kinase-C activation in osteoblast-like cells modulates responsiveness to estrogen and estrogen receptor levels. 
  • Exploratory analysis of Fas gene polymorphisms in pediatric osteosarcoma patients. 
  • Exposure of human osteosarcoma and bone marrow cells to tumour-targeted alpha-particles and gamma-irradiation: analysis of cell survival and microdosimetry. 
  • Expression of osteocalcin and its transcriptional regulators core-binding factor alpha 1 and MSX2 in osteoid-forming tumours. 
  • FOXO transcription factors control E2F1 transcriptional specificity and apoptotic function. 
  • Fine needle aspiration of osteogenic sarcoma metastatic to the lung. A report of four cases. 
  • Fine structure of a radiation-induced osteogenic sarcoma. 
  • Free vascularized fibula in traumatic long bone defects and in limb salvaging following tumor resection: comparative study. 
  • Genetic determinants of childhood and adult height associated with osteosarcoma risk. 
  • Human smooth muscle alpha-actin gene is a transcriptional target of the p53 tumor suppressor protein. 
  • Identification of CD146 as a marker enriched for tumor-propagating capacity reveals targetable pathways in primary human sarcoma. 
  • Identifying Modifiable and Non-modifiable Risk Factors of Readmission and Short-Term Mortality in Osteosarcoma: A National Cancer Database Study. 
  • Imaging of human tumors and organs with N-13-labeled L-methionine. 
  • Immune dysregulation and osteosarcoma: Staphylococcus aureus downregulates TGF-β and heightens the inflammatory signature in human and canine macrophages suppressed by osteosarcoma. 
  • Immunotherapy for osteosarcoma: Where do we go from here? 
  • In situ mass spectrometry imaging reveals heterogeneous glycogen stores in human normal and cancerous tissues. 
  • Incidence of anemia in children with solid tumors or Hodgkin disease. 
  • Increased expression of S100A6 is associated with decreased metastasis and inhibition of cell migration and anchorage independent growth in human osteosarcoma. 
  • Induction of wild-type p53 activity in human cancer cells by ribozymes that repair mutant p53 transcripts. 
  • Initial testing (stage 1) of the kinesin spindle protein inhibitor ispinesib by the pediatric preclinical testing program. 
  • Intra-arterial cisplatin with or without radiation in limb-sparing for canine osteosarcoma. 
  • Intra-arterial cisplatinum in preparation for the limb salvage procedure. 
  • Intrathoracic metastasis from an extrathoracic malignancy: a radiographic approach to patient evaluation. 
  • Involvement and targeted intervention of dysregulated Hedgehog signaling in osteosarcoma. 
  • Isolation of cowpox virus A-type inclusions and characterization of their major protein component. 
  • Limb salvage procedures in children with osteosarcoma. 
  • Limb salvage versus amputation in patients with osteosarcoma of the extremities: an update in the modern era using the National Cancer Database. 
  • Lipoid pneumonia in an adolescent girl secondary to use of lip gloss. 
  • Local complications after limb-salvage surgery for pediatric bone tumours: a pictorial essay. 
  • Localization and quantitation of hexabrachion (tenascin) in skin, embryonic brain, tumors, and plasma. 
  • Long-term survival following total sacrectomy with reconstruction for the treatment of primary osteosarcoma of the sacrum. A case report. 
  • Longitudinal follow-up of adult survivors of Ewing sarcoma: A report from the Childhood Cancer Survivor Study. 
  • Loss of ATRX promotes aggressive features of osteosarcoma with increased NF-κB signaling and integrin binding. 
  • Loss of p16(INK4a) expression correlates with decreased survival in pediatric osteosarcomas. 
  • Malignant giant cell tumor of soft parts. 
  • Malignant mesothelioma with heterologous elements: clinicopathological correlation of 27 cases and literature review. 
  • Management of pelvic sarcoma. 
  • Management of primary sarcomas of the pulmonary artery and reperfusion intrabronchial hemorrhage. 
  • Massive allografts in the treatment of osteosarcoma and Ewing sarcoma in children and adolescents. 
  • Messenger RNAs of a strongly-expressed late gene of cowpox virus contain 5'-terminal poly(A) sequences. 
  • Microsurgical salvage of the intractable oral vestibule. 
  • Multiple relapses of Clostridium difficile-associated diarrhea in a cancer patient. Successful control with long-term cholestyramine therapy. 
  • Osteogenic sarcoma of the head and neck. The UCLA experience. 
  • Osteosarcomatosis. 
  • Overexpression of integrin alphav promotes human osteosarcoma cell populated collagen lattice contraction and cell migration. 
  • PET imaging of osteosarcoma in dogs using a fluorine-18-labeled monoclonal antibody Fab fragment. 
  • Perinatal factors associated with clinical presentation of osteosarcoma in children and adolescents. 
  • Pharmacokinetics and toxicity of high-dose intravenous methotrexate in the treatment of leptomeningeal carcinomatosis. 
  • Preclinical Testing of a Novel Niclosamide Stearate Prodrug Therapeutic (NSPT) Shows Efficacy Against Osteosarcoma. 
  • Progress against childhood cancer: the Pediatric Oncology Group experience. 
  • Protein expression and functional analysis of the FHIT gene in human tumor cells. 
  • Quantitative scanning of osteogenic sarcoma with nitrogen-13-labeled L-glutamate. 
  • Quotient imaging with N-13 L-glutamate in osteogenic sarcoma: correlation with tumor viability. 
  • Randomized Double-Blind Phase II Study of Regorafenib in Patients With Metastatic Osteosarcoma. 
  • Receptor tyrosine kinase inhibitors for the treatment of osteosarcoma and Ewing sarcoma. 
  • Registration of three-dimensional magnetic resonance and radionuclide skeletal images. 
  • Response rate as an endpoint in clinical trials. 
  • Rotationplasty after failed limb-sparing tumor surgery: a report of two cases. 
  • Sarcoma treatment in the era of molecular medicine. 
  • Sarcomas arising in Paget disease of bone: a clinicopathologic analysis of 70 cases. 
  • Sarcomas in the elderly. 
  • Single-round selection yields a unique retroviral envelope utilizing GPR172A as its host receptor. 
  • Stapled peptides as scaffolds for developing radiotracers for intracellular targets: Preliminary evaluation of a radioiodinated MDM2-binding stapled peptide in the SJSA-1 osteosarcoma model. 
  • Synthesis and purification of sodium [11C]benzoate for physiological and metabolic studies: evaluation in a tumor-bearing dog. 
  • Systemic doxorubicin and intraarterial cisplatin preoperative chemotherapy plus postoperative adjuvant chemotherapy in patients with osteosarcoma. 
  • TP53 intron 1 hotspot rearrangements are specific to sporadic osteosarcoma and can cause Li-Fraumeni syndrome. 
  • The combined use of the Ilizarov method and microsurgical techniques for limb salvage. 
  • The effects of clinically relevant hyperthermic temperatures on the kinetic binding parameters of a monoclonal antibody. 
  • The fibula-flexor hallucis longus osteomuscular flap. 
  • The integrin-linked kinase regulates cell morphology and motility in a rho-associated kinase-dependent manner. 
  • The nucleolar localization domain of the catalytic subunit of human telomerase. 
  • The oncoprotein DEK affects the outcome of PARP1/2 inhibition during mild replication stress. 
  • The problem of benign pulmonary nodules in children receiving cytotoxic chemotherapy. 
  • The value of radionuclide bone imaging in selected patients with osteogenic sarcoma metastatic to lung. 
  • Toward a drug development path that targets metastatic progression in osteosarcoma. 
  • Transcription of a poxvirus early gene is regulated both by a short promoter element and by a transcriptional termination signal controlling transcriptional interference. 
  • Transforming growth factor beta mediates the estrogen induced inhibition of UMR106 cell growth. 
  • Two HLA Class II Gene Variants Are Independently Associated with Pediatric Osteosarcoma Risk. 
  • Utility of fine-needle aspiration in the diagnosis of primary osteosarcoma. 
  • Validation of the Brazilian version of the musculoskeletal tumor society rating scale for lower extremity bone sarcoma. 
  • Vascularized fibula-based physis transfer for pediatric proximal humerus reconstruction. 
  • Whole-body magnetic resonance imaging (WB-MRI) as surveillance for subsequent malignancies in survivors of hereditary retinoblastoma: a pilot study. 
  • YJ5 as an immunohistochemical marker of osteogenic lineage.