Sarcoplasmic Reticulum
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Subject Areas on Research
- Ankyrin-B coordinates the Na/K ATPase, Na/Ca exchanger, and InsP3 receptor in a cardiac T-tubule/SR microdomain.
- Ankyrin-B is required for intracellular sorting of structurally diverse Ca2+ homeostasis proteins.
- Association of chronic congestive heart failure in humans with an intrinsic upregulation in skeletal muscle sarcoplasmic reticulum calcium ion adenosine triphosphatase activity.
- Biochemical characterization of the Ca2+ release channel of skeletal and cardiac sarcoplasmic reticulum.
- Calcium Signaling and Cardiac Arrhythmias.
- Calcium accumulation by isolated sarcoplasmic reticulum of skeletal muscle during development in tissue culture.
- Cardiac and muscle fatigue due to relative functional overload induced by excessive stimulation, hypersensitive excitation-contraction coupling, or diminished performance capacity correlates with sarcoplasmic reticulum failure.
- Classes of thiols that influence the activity of the skeletal muscle calcium release channel.
- Comparative stereology of mouse atria.
- Comparative stereology of the lizard and frog myocardium.
- Comparative stereology of the mouse and finch left ventricle.
- Cysteine-3635 is responsible for skeletal muscle ryanodine receptor modulation by NO.
- Disruption of sarcoendoplasmic reticulum calcium ATPase function in Drosophila leads to cardiac dysfunction.
- Drosophila as a model for the identification of genes causing adult human heart disease.
- Eca1, a sarcoplasmic/endoplasmic reticulum Ca2+-ATPase, is involved in stress tolerance and virulence in Cryptococcus neoformans.
- Effects of HMGB1 on in vitro responses of isolated muscle fibers and functional aspects in skeletal muscles of idiopathic inflammatory myopathies.
- Effects of perchlorate on the molecules of excitation-contraction coupling of skeletal and cardiac muscle.
- Enhanced myocardial relaxation in vivo in transgenic mice overexpressing the beta2-adrenergic receptor is associated with reduced phospholamban protein.
- Evidence for a Ca2+ channel within the ryanodine receptor complex from cardiac sarcoplasmic reticulum.
- Evidence for a junctional feet-ryanodine receptor complex from sarcoplasmic reticulum.
- Fenestrations of sarcoplasmic reticulum. Delineation by lanthanum acting as a fortuitous tracer and in situ negative stain.
- Glycogen debranching enzyme is associated with rat skeletal muscle sarcoplasmic reticulum.
- High-affinity [3H]PN200-110 and [3H]ryanodine binding to rabbit and frog skeletal muscle.
- Hypoxia reprograms calcium signaling and regulates myoglobin expression.
- Junctophilin-2 expression silencing causes cardiocyte hypertrophy and abnormal intracellular calcium-handling.
- Lamellar junctional sarcoplasmic reticulum. A specialization of cardiac sarcoplasmic reticulum.
- Lumenal sites and C terminus accessibility of the skeletal muscle calcium release channel (ryanodine receptor).
- Muscle membrane protein kinase in myotonic muscular dystrophy.
- Myocardial myoglobin deficiency in various animal models of congestive heart failure.
- Mystery of biphasic defibrillation waveform efficacy is it calcium?
- Nitric oxide regulation of myocardial contractility and calcium cycling: independent impact of neuronal and endothelial nitric oxide synthases.
- Overexpression of the rat sarcoplasmic reticulum Ca2+ ATPase gene in the heart of transgenic mice accelerates calcium transients and cardiac relaxation.
- Oxygen-coupled redox regulation of the skeletal muscle ryanodine receptor-Ca2+ release channel by NADPH oxidase 4.
- Peripheral couplings in adult vertebrate skeletal muscle. Anatomical observations and functional implications.
- Peripheral couplings in human skeletal muscle.
- Purification and reconstitution of the calcium release channel from skeletal muscle.
- Purification and reconstitution of the ryanodine- and caffeine-sensitive Ca2+ release channel complex from muscle sarcoplasmic reticulum.
- Rapid ventricular pacing of dogs to heart failure: biochemical and physiological studies.
- Reduced junctional Na+/Ca2+-exchanger activity contributes to sarcoplasmic reticulum Ca2+ leak in junctophilin-2-deficient mice.
- Regulation of the cardiac muscle ryanodine receptor by O(2) tension and S-nitrosoglutathione.
- STIM1 enhances SR Ca2+ content through binding phospholamban in rat ventricular myocytes.
- STIM1 signalling controls store-operated calcium entry required for development and contractile function in skeletal muscle.
- STIM1-Ca2+ signaling modulates automaticity of the mouse sinoatrial node.
- Sarcoplasmic reticulum Ca-release channel and ATP-synthesis activities are early myocardial markers of heart failure produced by rapid ventricular pacing in dogs.
- Solubilization of membrane proteins for two-dimensional gel electrophoresis: identification of sarcoplasmic reticulum membrane proteins.
- Structural and functional characterization of the purified cardiac ryanodine receptor-Ca2+ release channel complex.
- T-tubule depolarization-induced SR Ca2+ release is controlled by dihydropyridine receptor- and Ca(2+)-dependent mechanisms in cell homogenates from rabbit skeletal muscle.
- Targeted overexpression of phospholamban to mouse atrium depresses Ca2+ transport and contractility.
- Thapsigargin stimulates Ca2+ entry in vascular smooth muscle cells: nicardipine-sensitive and -insensitive pathways.
- The skeletal muscle calcium release channel: coupled O2 sensor and NO signaling functions.
- The superfast extraocular myosin (MYH13) is localized to the innervation zone in both the global and orbital layers of rabbit extraocular muscle.
- To excite a heart: a bird's view.
- Transgenic overexpression of the Ca2+-binding protein S100A1 in the heart leads to increased in vivo myocardial contractile performance.
- Ultrastructure of heart muscle.
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Keywords of People
- Bennett, Vann, George Barth Geller Distinguished Professor of Molecular Biology, Duke Cancer Institute
- Erickson, Harold Paul, James B. Duke Distinguished Professor of Cell Biology, Cell Biology