Schizosaccharomyces

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  Subject Areas on Research

  • A conserved family of enzymes that phosphorylate inositol hexakisphosphate. 
  • A copper-sensing transcription factor regulates iron uptake genes in Schizosaccharomyces pombe. 
  • A heterochromatin barrier partitions the fission yeast centromere into discrete chromatin domains. 
  • A probabilistic model for cell cycle distributions in synchrony experiments. 
  • An Antifungal Combination Matrix Identifies a Rich Pool of Adjuvant Molecules that Enhance Drug Activity against Diverse Fungal Pathogens. 
  • An RNA polymerase III-dependent heterochromatin barrier at fission yeast centromere 1. 
  • Biochemical and functional characterization of inositol 1,3,4,5, 6-pentakisphosphate 2-kinases. 
  • Centromeric barrier disruption leads to mitotic defects in Schizosaccharomyces pombe. 
  • Characterization of an iron-sulfur cluster assembly protein (ISU1) from Schizosaccharomyces pombe. 
  • Characterization of proteins that interact with the cell-cycle regulatory protein Ran/TC4. 
  • Characterization of vps33+, a gene required for vacuolar biogenesis and protein sorting in Schizosaccharomyces pombe. 
  • Conservation, duplication, and loss of the Tor signaling pathway in the fungal kingdom. 
  • Conserved cAMP signaling cascades regulate fungal development and virulence. 
  • Dial 9-1-1 for DNA damage: the Rad9-Hus1-Rad1 (9-1-1) clamp complex. 
  • Dicentric chromosomes: unique models to study centromere function and inactivation. 
  • Dissection of the relative contribution of the Schizosaccharomyces pombe Ctr4 and Ctr5 proteins to the copper transport and cell surface delivery functions. 
  • Epigenetic regulation of gene expression: the effect of altered chromatin structure from yeast to mammals. 
  • Essential roles of class E Vps proteins for sorting into multivesicular bodies in Schizosaccharomyces pombe. 
  • Experimental determination of rates of concerted evolution. 
  • Fission yeast Cyk3p is a transglutaminase-like protein that participates in cytokinesis and cell morphogenesis. 
  • Functions of fission yeast orp2 in DNA replication and checkpoint control. 
  • Gene conversion between repeated genes. 
  • Identification and characterization of a human homolog of the Schizosaccharomyces pombe ras-like gene YPT-3. 
  • Identification and characterization of two Ca2+/CaM-dependent protein kinases required for normal nuclear division in Aspergillus nidulans. 
  • Identification of Drosophila cytoskeletal proteins by induction of abnormal cell shape in fission yeast. 
  • Identification of a novel high affinity copper transport complex in the fission yeast Schizosaccharomyces pombe. 
  • Implications for proteasome nuclear localization revealed by the structure of the nuclear proteasome tether protein Cut8. 
  • Inportance of phosphatidylinositol 3-phosphate in sporulation of Schizosaccharomyces pombe. 
  • Isolation of suppressor mutants of phosphatidylinositol 3-phosphate 5-kinase deficient cells in Schizosaccharomyces pombe. 
  • Membrane localization of the kinase which phosphorylates p34cdc2 on threonine 14. 
  • Microtubule organization: cell shape is destiny. 
  • Microtubule-driven multimerization recruits ase1p onto overlapping microtubules. 
  • Neuronal cell shape and neurite initiation are regulated by the Ndr kinase SAX-1, a member of the Orb6/COT-1/warts serine/threonine kinase family. 
  • Pcp1p, an Spc110p-related calmodulin target at the centrosome of the fission yeast Schizosaccharomyces pombe. 
  • Phosphatases join kinases in DNA-damage response pathways. 
  • RNA interference: silencing in the cytoplasm and nucleus. 
  • RNAi function, diversity, and loss in the fungal kingdom. 
  • Role of phosphatidylinositol 3-phosphate in formation of forespore membrane in Schizosaccharomyces pombe. 
  • Role of septins in the orientation of forespore membrane extension during sporulation in fission yeast. 
  • Schizosaccharomyces pombe Sst4p, a conserved Vps27/Hrs homolog, functions downstream of phosphatidylinositol 3-kinase Pik3p to mediate proper spore formation. 
  • Sorting nexin homologues are targets of phosphatidylinositol 3-phosphate in sporulation of Schizosaccharomyces pombe. 
  • Specificity determinants in phosphoinositide dephosphorylation: crystal structure of an archetypal inositol polyphosphate 5-phosphatase. 
  • Spindle function in yeast: a human motor to the rescue. 
  • Symmetrically dividing cells of the fission yeast schizosaccharomyces pombe do age. 
  • The impact of local genome sequence on defining heterochromatin domains. 
  • The mammalian Rad24 homologous to yeast Saccharomyces cerevisiae Rad24 and Schizosaccharomyces pombe Rad17 is involved in DNA damage checkpoint. 
  • The prevalence and regulation of antisense transcripts in Schizosaccharomyces pombe. 
  • To avoid a mating mishap, yeast focus and communicate. 
  • Topology and control of the cell-cycle-regulated transcriptional circuitry. 
  • Uncoupling of genomic and epigenetic signals in the maintenance and inheritance of heterochromatin domains in fission yeast. 
  • cis-acting DNA from fission yeast centromeres mediates histone H3 methylation and recruitment of silencing factors and cohesin to an ectopic site.