Scorpion Venoms

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  Subject Areas on Research

  • Cell penetration properties of maurocalcine, a natural venom peptide active on the intracellular ryanodine receptor. 
  • Charge substitutions at the voltage-sensing module of domain III enhance actions of site-3 and site-4 toxins on an insect sodium channel. 
  • Envenomation by the scorpion (Centruroides limbatus) outside its natural range and recognition of medically important scorpions. 
  • Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator. 
  • Mapping the interaction surface of scorpion β-toxins with an insect sodium channel. 
  • Release of corticotropin-releasing factor from rat brain regions in vitro. 
  • Sequence variations at I260 and A1731 contribute to persistent currents in Drosophila sodium channels. 
  • Substitutions in the domain III voltage-sensing module enhance the sensitivity of an insect sodium channel to a scorpion beta-toxin. 
  • The differential preference of scorpion alpha-toxins for insect or mammalian sodium channels: implications for improved insect control. 
  • The insecticidal potential of scorpion beta-toxins. 
  • Toxin and kinetic profile of rat brain type III sodium channels expressed in Xenopus oocytes.