Selection, Genetic

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  Subject Areas on Research

  • A catalog of neutral and deleterious polymorphism in yeast. 
  • A conservative test of genetic drift in the endosymbiotic bacterium Buchnera: slightly deleterious mutations in the chaperonin groEL. 
  • A gain-of-function polymorphism controlling complex traits and fitness in nature. 
  • A haplotype map of the human genome. 
  • A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response. 
  • A high-resolution map of human evolutionary constraint using 29 mammals. 
  • A multilocus sequence survey in Arabidopsis thaliana reveals a genome-wide departure from a neutral model of DNA sequence polymorphism. 
  • A refined model of the genomic basis for phenotypic variation in vertebrate hemostasis. 
  • A second generation human haplotype map of over 3.1 million SNPs. 
  • A strongly selected mutation in the HIV-1 genome is independent of T cell responses and neutralizing antibodies. 
  • A system of transposon mutagenesis for bacteriophage T4. 
  • A test of the chromosomal rearrangement model of speciation in Drosophila pseudoobscura. 
  • Acid potentiation of the capsaicin receptor determined by a key extracellular site. 
  • Acute-phase CD8 T cell responses that select for escape variants are needed to control live attenuated simian immunodeficiency virus. 
  • Adaptive evolution and fixation of drug-resistant Plasmodium falciparum genotypes in pregnancy-associated malaria: 9-year results from the QuEERPAM study. 
  • Adaptive evolution drives the diversification of zinc-finger binding domains. 
  • Adaptive evolution: evaluating empirical support for theoretical predictions. 
  • Allelic diversity and gene genealogy at the self-incompatibility locus in the Solanaceae. 
  • An evolutionary framework for treating pediatric sarcomas. 
  • Analyses on mutation patterns, detection of population bottlenecks, and suggestion of deleterious-compensatory evolution among members of the genus Potyvirus. 
  • Ancestry adjustment improves genome-wide estimates of regional intolerance. 
  • Ancient and recent positive selection transformed opioid cis-regulation in humans. 
  • Ancient polymorphisms contribute to genome-wide variation by long-term balancing selection and divergent sorting in Boechera stricta. 
  • Antagonistic selection and pleiotropy constrain the evolution of plant chemical defenses. 
  • Antibiotics as a selective driver for conjugation dynamics. 
  • Approximating selective sweeps. 
  • Architecture of the human regulatory network derived from ENCODE data. 
  • Balancing selection and trans-specific polymorphisms. 
  • Balancing selection on a floral polymorphism. 
  • Bone-associated gene evolution and the origin of flight in birds. 
  • Buffering of life histories against environmental stochasticity: accounting for a spurious correlation between the variabilities of vital rates and their contributions to fitness. 
  • Changes in phenology can alter patterns of natural selection: the joint evolution of germination time and postgermination traits. 
  • Coevolution of self-fertilization and inbreeding depression. I. Mutation-selection balance at one and two loci. 
  • Coevolution of the major histocompatibility complex and the t-complex in the mouse. I. Generation and maintenance of high complementarity associations. 
  • Coevolution of the major histocompatibility complex and the t-complex in the mouse. II. Modification of response to sharing of histocompatibility antigens. 
  • Coevolution to the edge of chaos: coupled fitness landscapes, poised states, and coevolutionary avalanches. 
  • Comment on "Evolutionary paths underlying flower color variation in Antirrhinum" 
  • Commentary: When does understanding phenotypic evolution require identification of the underlying genes? 
  • Comparative Developmental Transcriptomics Reveals Rewiring of a Highly Conserved Gene Regulatory Network during a Major Life History Switch in the Sea Urchin Genus Heliocidaris. 
  • Comparative Genomic Analysis of the Pheromone Receptor Class 1 Family (V1R) Reveals Extreme Complexity in Mouse Lemurs (Genus, Microcebus) and a Chromosomal Hotspot across Mammals. 
  • Comparative genomic analysis of fungal genomes reveals intron-rich ancestors. 
  • Comparative genomics based on massive parallel transcriptome sequencing reveals patterns of substitution and selection across 10 bird species. 
  • Comparative genomics reveals insights into avian genome evolution and adaptation. 
  • Comparing methods for detecting multilocus adaptation with multivariate genotype-environment associations. 
  • Complex trait divergence contributes to environmental niche differentiation in ecological speciation of Boechera stricta. 
  • Connecting recombination, nucleotide diversity and species divergence in Drosophila. 
  • Continental-level population differentiation and environmental adaptation in the mushroom Suillus brevipes. 
  • Contrasts between adaptive coding and noncoding changes during human evolution. 
  • Convergent adaptation of human lactase persistence in Africa and Europe. 
  • Convergent evolution of escape from hepaciviral antagonism in primates. 
  • Correctly estimating how environmental stochasticity influences fitness and population growth. 
  • Correlation between env V1/V2 region diversification and neutralizing antibodies during primary infection by simian immunodeficiency virus sm in rhesus macaques. 
  • Costs of resistance and correlational selection in the multiple-herbivore community of Solanum carolinense. 
  • Culture and the Constructal-Law evolution of the human and machine species: comment on "An evolutionary framework for cultural change: selectionism versus communal exchange" by L. Gabora. 
  • DNA copy number evolution in Drosophila cell lines. 
  • Deciphering human immunodeficiency virus type 1 transmission and early envelope diversification by single-genome amplification and sequencing. 
  • Deep Sequencing of Influenza A Virus from a Human Challenge Study Reveals a Selective Bottleneck and Only Limited Intrahost Genetic Diversification. 
  • Defending information-free genocentrism. 
  • Deleterious mutations and genetic variation for flower size in Mimulus guttatus. 
  • Dependence of morphometric allometries on the growth kinetics of body parts. 
  • Detecting differential copy number variation between groups of samples. 
  • Developmental causes of allometry: new models and implications for phenotypic plasticity and evolution. 
  • Developmental stress, song-learning, and cognition. 
  • Differential adaptation to a harsh granite outcrop habitat between sympatric Mimulus species. 
  • Differential patterns of male and female mtDNA exchange across the Atlantic Ocean in the blue mussel, Mytilus edulis. 
  • Distinguishing between selection and population expansion in an experimental lineage of bacteriophage T7. 
  • Divergent selection on flowering time contributes to local adaptation in Mimulus guttatus populations. 
  • Diversity in the weapons of sexual selection: horn evolution in the beetle genus Onthophagus (Coleoptera: Scarabaeidae). 
  • Does evolutionary theory need a rethink? 
  • Drosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution. 
  • Drosophila mutants suggest a strong drive toward complexity in evolution 
  • DsdA (D-serine deaminase): a new heterologous MX cassette for gene disruption and selection in Saccharomyces cerevisiae. 
  • Dynamic functional evolution of an odorant receptor for sex-steroid-derived odors in primates. 
  • Ecological factors influence balancing selection on leaf chemical profiles of a wildflower. 
  • Economic weights for restriction of selection index as optimal strategy for combining multiple traits. 
  • Effects of maternal source and progeny microhabitat on natural selection and population dynamics in Alliaria petiolata. 
  • Effects of selection and mutation on mitochondrial variation and inferences of historical population expansion in a Caribbean reef fish. 
  • Efficient purging of deleterious mutations in plants with haploid selfing. 
  • Endosymbiont evolution: predictions from theory and surprises from genomes. 
  • Environmental adaptation contributes to gene polymorphism across the Arabidopsis thaliana genome. 
  • Evidence for GC-biased gene conversion as a driver of between-lineage differences in avian base composition. 
  • Evidence for selection at multiple allozyme loci across a mussel hybrid zone. 
  • Evidence of adaptive divergence in plasticity: density- and site-dependent selection on shade-avoidance responses in Impatiens capensis. 
  • Evidence of viral adaptation to HLA class I-restricted immune pressure in chronic hepatitis C virus infection. 
  • Evolution of a polyphenism by genetic accommodation. 
  • Evolution of flux control in the glucosinolate pathway in Arabidopsis thaliana. 
  • Evolution of resistance to a multiple-herbivore community: genetic correlations, diffuse coevolution, and constraints on the plant's response to selection. 
  • Evolution of the gene network underlying wing polyphenism in ants. 
  • Evolution of the segregation ratio: modification of gene conversion and meiotic drive. 
  • Evolution. CNCing is believing. 
  • Evolutionary analysis of the well characterized endo16 promoter reveals substantial variation within functional sites. 
  • Evolutionary and biomedical insights from a marmoset diploid genome assembly. 
  • Evolutionary biology: Genes to make new species. 
  • Evolutionary dynamics of an Arabidopsis insect resistance quantitative trait locus. 
  • Evolutionary dynamics of self-incompatibility alleles in Brassica. 
  • Evolutionary genetics: gene replacement and the genetics of speciation. 
  • Experimental evidence that selection favors character displacement in the ivyleaf morning glory. 
  • Explaining the heritability of an ecologically significant trait in terms of individual quantitative trait loci. 
  • Extensive evolutionary changes in regulatory element activity during human origins are associated with altered gene expression and positive selection. 
  • Extrapolating weak selection in evolutionary games. 
  • Extreme phenotypic divergence and the evolution of development. 
  • Extreme selective sweeps independently targeted the X chromosomes of the great apes. 
  • Falling palm fronds structure amazonian rainforest sapling communities. 
  • Four reasons for scepticism about a human major transition in social individuality. 
  • Functional evolution of an anthocyanin pathway enzyme during a flower color transition. 
  • Functional evolution of mammalian odorant receptors. 
  • Functional organization of the genome may shape the species boundary in the house mouse. 
  • Further selection of rat lines differing in 5-HT-1A receptor sensitivity: behavioral and functional correlates. 
  • Gene expression divergence recapitulates the developmental hourglass model. 
  • Gene flow, divergent selection and resistance to introgression in two species of morning glories (Ipomoea). 
  • Gene loss, adaptive evolution and the co-evolution of plumage coloration genes with opsins in birds. 
  • Genetic Consequences of Biologically Altered Environments. 
  • Genetic architecture and adaptation of flowering time among environments. 
  • Genetic comparisons yield insight into the evolution of enamel thickness during human evolution. 
  • Genetic evidence for long-term population decline in a savannah-dwelling primate: inferences from a hierarchical bayesian model. 
  • Genetic isolation between two recently diverged populations of a symbiotic fungus. 
  • Genetic mechanisms and evolutionary significance of natural variation in Arabidopsis. 
  • Genetic trade-offs and conditional neutrality contribute to local adaptation. 
  • Genetic variance in fitness indicates rapid contemporary adaptive evolution in wild animals. 
  • Genetics of Brassica rapa (syn. campestris). 2. Multiple disease resistance to three fungal pathogens: Peronospora parasitica, Albugo candida and Leptosphaeria maculans. 
  • Genetics of incipient speciation in Drosophila mojavensis. I. Male courtship song, mating success, and genotype x environment interactions. 
  • Genetics. Origin of species in overdrive. 
  • Genome-wide detection and characterization of positive selection in human populations. 
  • Genomic and physiological responses to strong selective pressure during late organogenesis: few gene expression changes found despite striking morphological differences. 
  • Genomic impacts of chromosomal inversions in parapatric Drosophila species. 
  • Geographic selection in the small heat shock gene complex differentiating populations of Drosophila pseudoobscura. 
  • Glimpse of natural selection of long-lived T-cell clones in healthy life. 
  • Globally Relaxed Selection and Local Adaptation in Boechera stricta. 
  • Glutathione activates virulence gene expression of an intracellular pathogen. 
  • HLA antigen structural gene mutants selected with an allospecific monoclonal antibody. 
  • Heterologous URA3MX cassettes for gene replacement in Saccharomyces cerevisiae. 
  • How cells get the right chromosomes. 
  • How reliable is song learning accuracy as a signal of male early condition? 
  • Human genetic admixture through the lens of population genomics. 
  • Human genetic admixture. 
  • Human genomic regions with exceptionally high levels of population differentiation identified from 911 whole-genome sequences. 
  • IDH1(R132) mutation identified in one human melanoma metastasis, but not correlated with metastases to the brain. 
  • Identification of two genes causing reinforcement in the Texas wildflower Phlox drummondii. 
  • Identifying branch-specific positive selection throughout the regulatory genome using an appropriate proxy neutral. 
  • Impaired active avoidance responding in rats selectively bred for increased cholinergic function. 
  • Improved EBV shuttle vectors. 
  • In it for the long haul: evolutionary consequences of persistent endosymbiosis. 
  • Increased hypothermic responses to ethanol in rats selectively bred for cholinergic supersensitivity. 
  • Individual variation in inbreeding depression: the roles of inbreeding history and mutation. 
  • Information content of female copulation calls in yellow baboons. 
  • Initial sequencing and comparative analysis of the mouse genome. 
  • Integrative annotation of variants from 1092 humans: application to cancer genomics. 
  • Interferon and ribavirin therapy does not select for resistance mutations in hepatitis C virus polymerase. 
  • Interpreting the genomic landscape of speciation: a road map for finding barriers to gene flow. 
  • Interrogating the Roles of Mutation-Selection Balance, Heterozygote Advantage, and Linked Selection in Maintaining Recessive Lethal Variation in Natural Populations. 
  • Introducing MX Cassettes into Saccharomyces cerevisiae. 
  • Known mutator alleles do not markedly increase mutation rate in clinical Saccharomyces cerevisiae strains. 
  • Lessons from flower colour evolution on targets of selection. 
  • Life history in a model system: opening the black box with Arabidopsis thaliana. 
  • Life-history QTLS and natural selection on flowering time in Boechera stricta, a perennial relative of Arabidopsis. 
  • Linkage disequilibrium and signatures of positive selection around LINE-1 retrotransposons in the human genome. 
  • Local adaptation and species segregation in two mussel (Mytilus edulis x Mytilus trossulus) hybrid zones. 
  • Longitudinal Antigenic Sequences and Sites from Intra-Host Evolution (LASSIE) Identifies Immune-Selected HIV Variants. 
  • Looking for Darwin's footprints in the microbial world. 
  • MX Cassettes for Knocking Out Genes in Yeast. 
  • Major QTL controls adaptation to serpentine soils in Mimulus guttatus. 
  • Major histocompatibility complex variation and evolution at a single, expressed DQA locus in two genera of elephants. 
  • Mammalian Y chromosomes retain widely expressed dosage-sensitive regulators. 
  • Manipulation of insulin signaling phenocopies evolution of a host-associated polyphenism. 
  • Mapping of antibody specificities to VH gene families. 
  • Microgeographic patterns of genetic divergence and adaptation across natural environments in Boechera stricta (Brassicaceae) 
  • Molecular evolution of X-linked accessory gland proteins in Drosophila pseudoobscura. 
  • Molecular footprint of Medawar's mutation accumulation process in mammalian aging. 
  • Morning glory as a powerful model in ecological genomics: tracing adaptation through both natural and artificial selection. 
  • Multi-tasking as an ancient skill: When one gene does many things well. 
  • Multiple hybrid formation in natural populations: concerted evolution of the internal transcribed spacer of nuclear ribosomal DNA (ITS) in North American Arabis divaricarpa (Brassicaceae). 
  • Mutation exposed: a neutral explanation for extreme base composition of an endosymbiont genome. 
  • Mutational origin of new mating type specificities in flowering plants. 
  • Mutational selection in normal urothelium. 
  • Natural Selection Shapes Variation in Genome-wide Recombination Rate in Drosophila pseudoobscura. 
  • Natural positive selection and north-south genetic diversity in East Asia. 
  • Natural selection of memory-one strategies for the iterated prisoner's dilemma. 
  • Natural selection on a carbon cycling trait drives ecosystem engineering by Sphagnum (peat moss). 
  • Natural selection on a leaf-shape polymorphism in the ivyleaf morning glory (Ipomoea hederacea). 
  • Natural selection on a polymorphic disease-resistance locus in Ipomoea purpurea. 
  • Natural selection on extrafloral nectar production in Chamaecrista fasciculata: the costs and benefits of a mutualism trait. 
  • Nearshore fish (Pholis gunnellus) persists across the North Atlantic through multiple glacial episodes. 
  • Neutral evolution of the nonbinding region of the anthocyanin regulatory gene Ipmyb1 in Ipomoea. 
  • New tools for studying integration and modularity. 
  • Niche construction through germination cueing: life-history responses to timing of germination in Arabidopsis thaliana. 
  • Novel estrogen response elements identified by genetic selection in yeast are differentially responsive to estrogens and antiestrogens in mammalian cells. 
  • Nucleotide bias of DCL and AGO in plant anti-virus gene silencing. 
  • On the evolution of genetic incompatibility systems. III. Introduction of weak gametophytic self-incompatibility under partial inbreeding. 
  • On the evolution of genetic incompatibility systems. V. Origin of sporophytic self-incompatibility in response to overdominance in viability. 
  • On the evolution of genetic incompatibility systems. VI. A three-locus modifier model for the origin of gametophytic self-incompatibility. 
  • On the origin of meiotic reproduction: a genetic modifier model. 
  • Optimal sequence selection in proteins of known structure by simulated evolution. 
  • Origin, fate, and architecture of ecologically relevant genetic variation. 
  • Orion: Detecting regions of the human non-coding genome that are intolerant to variation using population genetics. 
  • Parallel evolution of drug resistance in HIV: failure of nonsynonymous/synonymous substitution rate ratio to detect selection. 
  • Pervasive Effects of Aging on Gene Expression in Wild Wolves. 
  • Phenotypic plasticity and adaptive evolution contribute to advancing flowering phenology in response to climate change. 
  • Phylogeography's past, present, and future: 10 years after Avise, 2000. 
  • Pioneering paradigms and magnificent manifestos--Leigh Van Valen's priceless contributions to evolutionary biology. 
  • Plant sex and the evolution of plant defenses against herbivores. 
  • Pleiotropy in the wild: the dormancy gene DOG1 exerts cascading control on life cycles. 
  • Pollen limitation and natural selection on floral characters in the yellow monkeyflower, Mimulus guttatus. 
  • Pollinator-mediated selection on flower color allele drives reinforcement. 
  • Polymorphic mimicry in Papilio dardanus: mosaic dominance, big effects, and origins. 
  • Polymorphism at the ribosomal DNA spacers and its relation to breeding structure of the widespread mushroom Schizophyllum commune. 
  • Popping Out MX Cassettes from Saccharomyces cerevisiae. 
  • Population Selection and Sequencing of Caenorhabditis elegans Wild Isolates Identifies a Region on Chromosome III Affecting Starvation Resistance. 
  • Population genetic and phylogenetic evidence for positive selection on regulatory mutations at the factor VII locus in humans. 
  • Population genetics of polymorphism and divergence under fluctuating selection. 
  • Population structure and local selection yield high genomic variation in Mimulus guttatus. 
  • Population-genomic inference of the strength and timing of selection against gene flow. 
  • Positive and negative selection LYS5MX gene replacement cassettes for use in Saccharomyces cerevisiae. 
  • Positive selection driving diversification in plant secondary metabolism. 
  • Positive selection on MMP3 regulation has shaped heart disease risk. 
  • Positive selection on a human-specific transcription factor binding site regulating IL4 expression. 
  • Predictable patterns of constraint among anthocyanin-regulating transcription factors in Ipomoea. 
  • Predicting the response to simultaneous selection: genetic architecture and physiological constraints. 
  • Primate brain architecture and selection in relation to sex. 
  • Promoter regions of many neural- and nutrition-related genes have experienced positive selection during human evolution 
  • Randomization and selection of RNA to identify targets for RRM RNA-binding proteins and antibodies. 
  • Rapid adaptation to malaria facilitated by admixture in the human population of Cabo Verde. 
  • Reciprocal gut microbiota transplants from zebrafish and mice to germ-free recipients reveal host habitat selection. 
  • Recombinant DNA strategies in genetic neurological diseases. 
  • Recombination modulates how selection affects linked sites in Drosophila. 
  • Recombination rate variation in closely related species. 
  • Reduced selective constraint in endosymbionts: elevation in radical amino acid replacements occurs genome-wide. 
  • Reducing environmental bias when measuring natural selection. 
  • Reinforcement and other consequences of sympatry. 
  • Relating ranging ecology, limb length, and locomotor economy in terrestrial animals. 
  • Relationship between functional profile of HIV-1 specific CD8 T cells and epitope variability with the selection of escape mutants in acute HIV-1 infection. 
  • Relaxed natural selection alone does not permit transposable element expansion within 4,000 generations in Escherichia coli. 
  • Relaxed selection among duplicate floral regulatory genes in Lamiales. 
  • Relaxed selection in the wild. 
  • Remarkably little variation in proteins encoded by the Y chromosome's single-copy genes, implying effective purifying selection. 
  • Repeated phenotypic changes highlight molecular targets of convergent evolution. 
  • Replicated Landscape Genomics Identifies Evidence of Local Adaptation to Urbanization in Wood Frogs. 
  • Seasonal mortality patterns in non-human primates: implications for variation in selection pressures across environments. 
  • Selection against admixture and gene regulatory divergence in a long-term primate field study. 
  • Selection and analysis of spontaneous reciprocal mitotic cross-overs in Saccharomyces cerevisiae. 
  • Selection favors loss of floral pigmentation in a highly selfing morning glory. 
  • Selection for character displacement is constrained by the genetic architecture of floral traits in the ivyleaf morning glory. 
  • Selection is no more efficient in haploid than in diploid life stages of an angiosperm and a moss. 
  • Selection on QTL and complex traits in complex environments. 
  • Selection through female fitness helps to explain the maintenance of male flowers. 
  • Selection through male function favors smaller floral display size in the common morning glory Ipomoea purpurea (Convolvulaceae). 
  • Selective inhibition of alcohol intake in diverse alcohol-preferring rat strains by the 5-HT2A antagonists amperozide and FG 5974. 
  • Selective trade-offs maintain alleles underpinning complex trait variation in plants. 
  • Sequence context of indel mutations and their effect on protein evolution in a bacterial endosymbiont. 
  • Short communication: HIV type 1 subtype C variants transmitted through the bottleneck of breastfeeding are sensitive to new generation broadly neutralizing antibodies directed against quaternary and CD4-binding site epitopes. 
  • Signatures of neutral evolution in exponentially growing tumors: A theoretical perspective. 
  • Sleep intensity and the evolution of human cognition. 
  • Slip into something more functional: selection maintains ancient frameshifts in homopolymeric sequences. 
  • Social cognitive evolution in captive foxes is a correlated by-product of experimental domestication. 
  • Spatial models for hybrid zones. 
  • Spatial working and reference memory in rats bred for autonomic sensitivity to cholinergic stimulation: acquisition, accuracy, speed, and effects of cholinergic drugs. 
  • Spatially and temporally varying selection on intrapopulation quantitative trait loci for a life history trade-off in Mimulus guttatus. 
  • Speciation by reinforcement: a model derived from studies of Drosophila. 
  • Speciation driven by natural selection in Drosophila. 
  • Statistical genetics of an annual plant, Impatiens capensis. II. Natural selection. 
  • Strain-Specific V3 and CD4 Binding Site Autologous HIV-1 Neutralizing Antibodies Select Neutralization-Resistant Viruses. 
  • Stress resistance declines with age: analysis of data from a survival experiment with Drosophila melanogaster. 
  • Strict evolutionary conservation followed rapid gene loss on human and rhesus Y chromosomes. 
  • Strong reinforcing selection in a Texas wildflower. 
  • Strong selection genome-wide enhances fitness tradeoffs across environments and episodes of selection 
  • Synergism and Antagonism of Proximate Mechanisms Enable and Constrain the Response to Simultaneous Selection on Body Size and Development Time: An Empirical Test Using Experimental Evolution. 
  • Systematic detection of positive selection in the human-pathogen interactome and lasting effects on infectious disease susceptibility. 
  • Systems Biology of Phenotypic Robustness and Plasticity. 
  • Targeted deletion of 5'HS2 of the murine beta-globin LCR reveals that it is not essential for proper regulation of the beta-globin locus. 
  • Targeted selection of HIV-specific antibody mutations by engineering B cell maturation. 
  • The Boechera model system for evolutionary ecology. 
  • The DNA sequence and biological annotation of human chromosome 1. 
  • The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers. 
  • The PIG-A mutation and absence of glycosylphosphatidylinositol-linked proteins do not confer resistance to apoptosis in paroxysmal nocturnal hemoglobinuria. 
  • The cost of reinforcement: selection on flower color in allopatric populations of Phlox drummondii. 
  • The earliest stages of adaptation in an experimental plant population: strong selection on QTLs for seed dormancy. 
  • The ecological, genetic and genomic architecture of local adaptation and population differentiation in Boechera stricta . 
  • The effective rate of influenza reassortment is limited during human infection. 
  • The effects of selection against spurious transcription factor binding sites. 
  • The evolution of intrinsic reproductive isolation in the genus Cakile (Brassicaceae). 
  • The evolution of quantitative traits in complex environments 
  • The evolution of self-control. 
  • The evolution of tolerance to deer herbivory: modifications caused by the abundance of insect herbivores. 
  • The evolutionary ecology of seed germination of Arabidopsis thaliana: variable natural selection on germination timing. 
  • The extent and genetic basis of phenotypic divergence in life history traits in Mimulus guttatus. 
  • The genetic architecture of gene expression levels in wild baboons. 
  • The genetic architecture of selection at the human dopamine receptor D4 (DRD4) gene locus. 
  • The genetic bottleneck in vertical transmission of subtype C HIV-1 is not driven by selection of especially neutralization-resistant virus from the maternal viral population. 
  • The genetics of sex ratio distortion by cytoplasmic infection under maternal and contagious transmission: an epidemiological study. 
  • The influence of neighbor relatedness on multilevel selection in the Great Lakes sea rocket. 
  • The neutral theory and natural selection in the HLA region. 
  • The role of developmental plasticity in evolutionary innovation. 
  • The roles of positive and negative selection in the molecular evolution of insect endosymbionts. 
  • The roots of human altruism. 
  • The standing pool of genomic structural variation in a natural population of Mimulus guttatus. 
  • The western painted turtle genome, a model for the evolution of extreme physiological adaptations in a slowly evolving lineage. 
  • Theories of kin and group selection: a population genetics perspective. 
  • Thousands of human mobile element fragments undergo strong purifying selection near developmental genes. 
  • Three periods of regulatory innovation during vertebrate evolution. 
  • Transcriptional regulation and the evolution of development. 
  • Transmission of single HIV-1 genomes and dynamics of early immune escape revealed by ultra-deep sequencing. 
  • Unifying genetic canalization, genetic constraint, and genotype-by-environment interaction: QTL by genomic background by environment interaction of flowering time in Boechera stricta. 
  • Unisexual reproduction enhances fungal competitiveness by promoting habitat exploration via hyphal growth and sporulation. 
  • Variables affecting the T cell receptor V beta repertoire heterogeneity of T cells infiltrating human renal allografts. 
  • Variation and selection in neural function. 
  • Variation in the fitness effects of mutations with population density and size in Escherichia coli. 
  • Waiting for two mutations: with applications to regulatory sequence evolution and the limits of Darwinian evolution. 
  • What can patterns of differentiation across plant genomes tell us about adaptation and speciation? 
  • When sensing is gambling: An experimental system reveals how plasticity can generate tunable bet-hedging strategies. 
  • Whole-genome comparison of Leu3 binding in vitro and in vivo reveals the importance of nucleosome occupancy in target site selection. 
  • Whole-genome positive selection and habitat-driven evolution in a shallow and a deep-sea urchin. 
  • Why flying dogs are rare: A general theory of luck in evolutionary transitions. 
  • minotaur: A platform for the analysis and visualization of multivariate results from genome scans with R Shiny. 
  • optix Drives the Repeated Convergent Evolution of Butterfly Wing Pattern Mimicry 
• 

  Keywords of People

  • Ferrari, Guido, Professor in Surgery, Molecular Genetics and Microbiology
  • Kelsoe, Garnett H., James B. Duke Distinguished Professor of Immunology, Integrative Immunobiology
  • Krangel, Michael S., George Barth Geller Distinguished Professor of Immunology, Integrative Immunobiology
  • McLendon, Roger Edwin, Professor of Pathology, Pathology
  • Mitchell-Olds, Thomas, Newman Ivey White Distinguished Professor of Biology, Biology
  • Wray, Gregory Allan, Professor of Biology, Evolutionary Anthropology