Sex Differentiation

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  Subject Areas on Research

  • A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation. 
  • AMH induces mesonephric cell migration in XX gonads. 
  • Androgens and masculinization of genitalia in the spotted hyaena (Crocuta crocuta). 2. Effects of prenatal anti-androgens. 
  • CBX2 is required to stabilize the testis pathway by repressing Wnt signaling. 
  • Cell proliferation is necessary for the determination of male fate in the gonad. 
  • Cellular mechanisms of sex determination in the red-eared slider turtle, Trachemys scripta. 
  • Chromosome segregation. Programmed to stay together. 
  • Deletion of Y chromosome sequences located outside the testis determining region can cause XY female sex reversal. 
  • Determining the sensitive developmental stages of intersex induction in medaka (Oryzias latipes) exposed to 17 beta-estradiol or testosterone. 
  • Effects of prenatal treatment with antiandrogens on luteinizing hormone secretion and sex steroid concentrations in adult spotted hyenas, Crocuta crocuta. 
  • Endocrine correlates of pregnancy in the ring-tailed lemur (Lemur catta): implications for the masculinization of daughters. 
  • Evolution of life cycle, colony morphology, and host specificity in the family Hydractiniidae (Hydrozoa, Cnidaria). 
  • Fgf9 induces proliferation and nuclear localization of FGFR2 in Sertoli precursors during male sex determination. 
  • Germ cell depletion does not alter the morphogenesis of the fetal testis or ovary in the red-eared slider turtle (Trachemys scripta). 
  • Germ cells are not required to establish the female pathway in mouse fetal gonads. 
  • Gonad morphogenesis in vertebrates: divergent means to a convergent end. 
  • Hormonal modulation of the cutaneous initiation of lordosis in infant and adult rats. 
  • Male-to-female sex reversal in mice lacking fibroblast growth factor 9. 
  • Mammalian sexual differentiation: lessons from the spotted hyena. 
  • Meiotic germ cells antagonize mesonephric cell migration and testis cord formation in mouse gonads. 
  • Mixed signals: development of the testis. 
  • Molecular biology and function of the androgen receptor in genital development. 
  • Molecular determinants of sexual differentiation. 
  • Neural crest-derived neurons invade the ovary but not the testis during mouse gonad development. 
  • Organizational effects of early gonadal secretions on sexual differentiation in spatial memory. 
  • Pleiotropic roles of the Msi1-like protein Msl1 in Cryptococcus neoformans. 
  • Predetermination of sexual fate in a turtle with temperature-dependent sex determination. 
  • Prenatal cocaine and/or nicotine exposure in rats: preliminary findings on long-term cognitive outcome and genital development at birth. 
  • Sexual development of the soma in the mouse. 
  • Sox8 is expressed at similar levels in gonads of both sexes during the sex determining period in turtles. 
  • Spotted hyaenas and the sexual spectrum: reproductive endocrinology and development. 
  • Stabilization of beta-catenin in XY gonads causes male-to-female sex-reversal. 
  • Steroidogenic factor 1 is the essential transcript of the mouse Ftz-F1 gene. 
  • Temperature, genes, and sex: a comparative view of sex determination in Trachemys scripta and Mus musculus. 
  • The PGD2 pathway, independently of FGF9, amplifies SOX9 activity in Sertoli cells during male sexual differentiation. 
  • The anti-androgen combination, flutamide plus finasteride, paradoxically suppressed LH and androgen concentrations in pregnant spotted hyenas, but not in males. 
  • The battle of the sexes: opposing pathways in sex determination. 
  • The effect of neonatal exposure to diethylstilbestrol, coumestrol, and beta-sitosterol on pituitary responsiveness and sexually dimorphic nucleus volume in the castrated adult rat. 
  • The effect of prenatal exposure to the phytoestrogen genistein on sexual differentiation in rats. 
  • The nuclear receptor steroidogenic factor 1 is essential for the formation of the ventromedial hypothalamic nucleus. 
  • The roles of steroidogenic factor-1 in reproductive function. 
  • Trophic effects of androgen: development and hormonal regulation of neuron number in a sexually dimorphic vocal motor nucleus.