Shock, Septic

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  Subject Areas on Research

  • A controlled clinical trial of E5 murine monoclonal IgM antibody to endotoxin in the treatment of gram-negative sepsis. The XOMA Sepsis Study Group. 
  • A prospective, multicenter derivation of a biomarker panel to assess risk of organ dysfunction, shock, and death in emergency department patients with suspected sepsis. 
  • A randomized trial of protocol-based care for early septic shock. 
  • Altered mitochondrial redox responses in gram negative septic shock in primates. 
  • American College of Critical Care Medicine Clinical Practice Parameters for Hemodynamic Support of Pediatric and Neonatal Septic Shock. 
  • Association between Initial Fluid Choice and Subsequent In-hospital Mortality during the Resuscitation of Adults with Septic Shock. 
  • Block-diagonal discriminant analysis and its bias-corrected rules. 
  • Calcium/calmodulin-dependent protein kinase kinase 2 regulates macrophage-mediated inflammatory responses. 
  • Capnocytophagia canimorsus sepsis in an asplenic heart transplant candidate with a left ventricular assist system. 
  • Circulating tetrahydrobiopterin concentrations in patients with septic shock. 
  • Clinical impact of stress dose steroids in patients with septic shock: insights from the PROWESS-Shock trial. 
  • Clostridial infection of a liver transplant treated with retransplantation. 
  • Development of the sympathetic nervous system response to endotoxicosis in the rat: importance of non-baroreflex mechanisms in pre-weanlings and adults. 
  • Differential expression of the nuclear-encoded mitochondrial transcriptome in pediatric septic shock. 
  • Disease progression in hemodynamically stable patients presenting to the emergency department with sepsis. 
  • Disseminated Mycobacterium immunogenum infection presenting with septic shock and skin lesions in a renal transplant recipient. 
  • Dopamine and dobutamine in septic shock. A comparison. 
  • Drotrecogin alfa (activated) in adults with septic shock. 
  • Early, Goal-Directed Therapy for Septic Shock - A Patient-Level Meta-Analysis. 
  • Epidemiology, pathophysiology and clinical presentation of gram-negative sepsis. 
  • Essential roles of S-nitrosothiols in vascular homeostasis and endotoxic shock. 
  • Etiologies of illness among patients meeting integrated management of adolescent and adult illness district clinician manual criteria for severe infections in northern Tanzania: implications for empiric antimicrobial therapy. 
  • Extracorporeal membrane oxygenation for neonatal and pediatric respiratory failure: an evidence-based review of the past decade (2002-2012). 
  • Four phases of intravenous fluid therapy: a conceptual model. 
  • Glucocorticoid therapy in sepsis/shock caused by gram-negative microorganisms. 
  • Glutamine and heat shock protein expression. 
  • Glutamine attenuates tumor necrosis factor-alpha release and enhances heat shock protein 72 in human peripheral blood mononuclear cells. 
  • Glutamine induces heat shock protein and protects against endotoxin shock in the rat. 
  • Gram-negative sepsis and endotoxic shock (lecture). 
  • Haemophagocytic lymphohistiocytosis mimicking septic shock after the initiation of chemotherapy for squamous cell carcinoma of the neck. 
  • Images in Anesthesiology: Examining the Edges of Extravasation. 
  • Incorporating Interprofessional Evidenced-Based Sepsis Simulation Education for Certified Nursing Assistants (CNAs) and Licensed Care Providers Within Long-term Care Settings for Process and Quality Improvement. 
  • Index of suspicion. 
  • Infectious complications after pulsatile-flow and continuous-flow left ventricular assist device implantation. 
  • Interleukin-1 receptor-associated kinase-1: more evidence. 
  • Intrathecal endotoxin: Intrathecal endotoxin: the role of the central nervous system in septic shock. 
  • Kilohertz frequency nerve block enhances anti-inflammatory effects of vagus nerve stimulation. 
  • Leukocyte entry into sites of inflammation requires overlapping interactions between the L-selectin and ICAM-1 pathways. 
  • Macro- and Microvascular Parameters After Toxic Shock Syndrome. 
  • Medical vs. surgical management of early pregnancy failure. 
  • Methylene blue reverses endotoxin-induced hypotension. 
  • Myocardial adenosine triphosphate levels during early sepsis. 
  • Neutrophils with myeloid derived suppressor function deplete arginine and constrain T cell function in septic shock patients. 
  • Nucleic acid-binding polymers as anti-inflammatory agents. 
  • Pathophysiology and treatment of septic shock in neonates. 
  • Phenoxybenzamine in septic shock. 
  • Photoperiodic adjustments in immune function protect Siberian hamsters from lethal endotoxemia. 
  • Protection from death in endotoxin shock: does fish oil need a LIF? 
  • Protocolized Care for Early Septic Shock (ProCESS) statistical analysis plan. 
  • Pyogenic liver abscesses: mortality-related factors. 
  • Reduction of cardiomyocyte S-nitrosylation by S-nitrosoglutathione reductase protects against sepsis-induced myocardial depression. 
  • Relative contribution of preload and afterload to the reduction in cardiac output caused by nitric oxide synthase inhibition with L-N(G)-methylarginine hydrochloride 546C88. 
  • Resistance of CD7-deficient mice to lipopolysaccharide-induced shock syndromes. 
  • Somatic mosaicism caused by monoallelic reversion of a mutation in T cells of a patient with ADA-SCID and the effects of enzyme replacement therapy on the revertant phenotype. 
  • Stunned myocardium in the toxic shock syndrome. 
  • Sudden infant death syndrome: a toxic response. 
  • Systemic loxoscelism in a nonendemic area: a diagnostic challenge for the unsuspecting physician. 
  • The American College of Critical Care Medicine Clinical Practice Parameters for Hemodynamic Support of Pediatric and Neonatal Septic Shock: Executive Summary. 
  • The Dose Makes the Poison: Comparing Epinephrine With Dopamine in Pediatric Septic Shock. 
  • The Effects of Alternative Resuscitation Strategies on Acute Kidney Injury in Patients with Septic Shock. 
  • The GENESIS project (GENeralized Early Sepsis Intervention Strategies): a multicenter quality improvement collaborative. 
  • The changing pattern of bacterial sepsis since the introduction of antibiotic therapy. 
  • The role of the central nervous system in septic shock. I. Pathologic changes following intraventricular and intracisternal endotoxin in the dog. 
  • The role of the central nervous system in septic shock. II. Hemodynamic, respiratory and metabolic effects of intracisternal or intraventricular endotoxin. 
  • The use of recombinant human activated protein C (drotrecogin alpha) in solid organ transplant recipients: case series and review of the literature. 
  • Thrombocytopenia in hospitalized patients with severe clostridium difficile infection. 
  • Toxic shock syndrome after inguinal hernia repair. Report of a case with patient survival. 
  • Toxic strep syndrome. 
  • Treatment of anemia with darbepoetin alfa in systolic heart failure. 
  • Urologic sepsis/shock. 
  • VA/Q abnormalities during gram negative sepsis. 
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  Keywords of People

  • Tsalik, Ephraim, Associate Professor of Medicine, Molecular Genetics and Microbiology