Sialic Acids

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  Subject Areas on Research

  • A CRISPR Activation Screen Identifies a Pan-avian Influenza Virus Inhibitory Host Factor. 
  • Carbohydrate on human factor VIII/von Willebrand factor. Impairment of function by removal of specific galactose residues. 
  • Characterization of new gangliosides of the lactotetraose series in murine xenografts of a human glioma cell line. 
  • Determination of gangliosides in six human primary medulloblastomas. 
  • Developmental regulation of neural cell adhesion molecule in human prefrontal cortex. 
  • Diversity in prokaryotic glycosylation: an archaeal-derived N-linked glycan contains legionaminic acid. 
  • Dobson backed NICE ruling on flu drug. 
  • Economic analysis of influenza vaccination and antiviral treatment for healthy working adults. 
  • Effect of desialylation on the biological properties of human plasminogen. 
  • Effectiveness of neuraminidase inhibitors in treatment and prevention of influenza A and B: systematic review and meta-analyses of randomised controlled trials. 
  • Factor VIII/von Willebrand protein. Modification of its carbohydrate causes reduced binding to platelets. 
  • Gangliosides in the human glioma cell line U-118 MG grown in culture or as xenografts in nude rats. 
  • Identification of the ligand-binding domains of CD22, a member of the immunoglobulin superfamily that uniquely binds a sialic acid-dependent ligand. 
  • Infantile sialic acid storage disease: a rare cause of cytoplasmic vacuolation in pediatric patients. 
  • Influenza immunization elicits antibodies specific for an egg-adapted vaccine strain. 
  • Interaction of desialated guinea pig erythrocytes with the classical and alternative pathways of guinea pig complement in vivo and in vitro. 
  • NICE to rule on influenza flu drug zanamivir. 
  • New observation of sialuria prompts detection of liver tumor in previously reported patient 
  • Polysialic acid expression is not necessary for motor neuron target selectivity. 
  • Preparation of cytidine 5'-monophospho-N-acetylneuraminic acid and uridine 5'-diphosphoglucuronic acid; syntheses of alpha-2, 6-sialyllactosamine, alpha-2, 6-sialyllactose, and hyaluronic acid. 
  • Relationship of sialic acid to function and in vivo survival of human factor VIII/von Willebrand factor protein. 
  • Schwann cell influence on motor neuron regeneration accuracy. 
  • Sialic acid content of plasminogen 2 glycoforms as a regulator of fibrinolytic activity. Isolation, carbohydrate analysis, and kinetic characterization of six glycoforms of plasminogen. 
  • Sialic acid prevents loss of large von Willebrand factor multimers by protecting against amino-terminal proteolytic cleavage. 
  • Sialyl-dimeric Lewis-X antigen expressed on mucin-like glycoproteins in colorectal cancer metastases. 
  • The abnormal surface characteristics of the red blood cell membrane in congenital dyserythropoietic anaemia type II (HEMPAS). 
  • The same epitope on CD22 of B lymphocytes mediates the adhesion of erythrocytes, T and B lymphocytes, neutrophils, and monocytes. 
  • Unique glycan signatures regulate adeno-associated virus tropism in the developing brain.