Sindbis Virus

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  Subject Areas on Research

  • Chimeric Sindbis/eastern equine encephalitis vaccine candidates are highly attenuated and immunogenic in mice. 
  • Chimeric alphavirus vaccine candidates for chikungunya. 
  • Conversion of Bcl-2 to a Bax-like death effector by caspases. 
  • Effect of alternating passage on adaptation of sindbis virus to vertebrate and invertebrate cells. 
  • Inhibition of nitric oxide synthesis increases mortality in Sindbis virus encephalitis. 
  • Intracerebral cytokine mRNA expression during fatal and nonfatal alphavirus encephalitis suggests a predominant type 2 T cell response. 
  • c-IAP1 is cleaved by caspases to produce a proapoptotic C-terminal fragment.