Sodium

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  Subject Areas on Research

  • 22Na+ and 86Rb+ transport in vascular smooth muscle of SHR, Wistar Kyoto, and Wistar rats. 
  • 23Na MRI combined with contrast-enhanced 1H MRI provides in vivo characterization of infarct healing. 
  • A comparison of 3% hypertonic saline and mannitol for brain relaxation during elective supratentorial brain tumor surgery. 
  • A fine line between molecular umbrella transport and ionophoric activity. 
  • A further subgroup analysis of the effects of the DASH diet and three dietary sodium levels on blood pressure: results of the DASH-Sodium Trial. 
  • A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis. 
  • A new container geometry for better sensitivity in radiometric measurements. 
  • A novel role for renal epithelial cells and the medullary sodium gradient in the local immune response. 
  • A primary role for K+ and Na+ efflux in the activation of apoptosis. 
  • A quantitative description of QX222 blockade of sodium channels in squid axons. 
  • A reappraisal of the concept of an abnormality of glutamine metabolism in primary gout. 
  • A silicone rubber that cures rapidly at body temperature. 
  • A sodium channel mutation identified in Aedes aegypti selectively reduces cockroach sodium channel sensitivity to type I, but not type II pyrethroids. 
  • A theoretical analysis of acute ischemia and infarction using ECG reconstruction on a 2-D model of myocardium. 
  • A voltage-gated calcium-selective channel encoded by a sodium channel-like gene. 
  • AT1A angiotensin receptors in the renal proximal tubule regulate blood pressure. 
  • ATP receptor activation potentiates a voltage-dependent Ca channel in hippocampal neurons. 
  • Absorption filtration. A tool for the measurement of ion tracer flux in native membranes and reconstituted lipid vesicles. 
  • Acetylcholine receptor from Torpedo. Preferential solubilization and efficient reintegration into lipid vesicles. 
  • Acetylcholine receptors from electroplax membranes: in vitro and in situ properties. 
  • Actions of Dendritic Cells in the Kidney during Hypertension. 
  • Activation by saccharides of a cation-selective pathway on canine lingual epithelium. 
  • Acute heart failure in elderly patients: worse outcomes and differential utility of standard prognostic variables. Insights from the PROTECT trial. 
  • Adhesion of acorn barnacles on surface-active borate glasses. 
  • Alkali Citrate Content of Common Over-the-Counter and Medical Food Supplements. 
  • Alkali action on the urinary crystallization of calcium salts: contrasting responses to sodium citrate and potassium citrate. 
  • Alterations in serum sodium in relation to atrial natriuretic factor and other neuroendocrine variables in experimental pacing-induced heart failure. 
  • An important role of a pyrethroid-sensing residue F1519 in the action of the N-alkylamide insecticide BTG 502 on the cockroach sodium channel. 
  • An upper limit for the electrogenic Na-K pump contribution to maximum diastolic potential in feline cardiac Purkinje fibers in steady state. 
  • Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney. 
  • Ankyrin and spectrin associate with voltage-dependent sodium channels in brain. 
  • Antenatal Bartter's syndrome: why is this not a lethal condition? 
  • Antiarrhythmic drug action. Blockade of the inward sodium current. 
  • Antillatoxin, a novel lipopeptide, enhances neurite outgrowth in immature cerebrocortical neurons through activation of voltage-gated sodium channels. 
  • Association of Visit-to-Visit Variability in Kidney Function and Serum Electrolyte Indexes With Risk of Adverse Clinical Outcomes Among Patients With Heart Failure With Preserved Ejection Fraction. 
  • Association of a reduction in central obesity and phosphorus intake with changes in urinary albumin excretion: the PREMIER study. 
  • Astringent-tasting compounds alter ion transport across isolated canine lingual epithelia. 
  • Atrial natriuretic factor: pharmacokinetics and cyclic GMP response in relation to biologic effects in severe heart failure. 
  • Author response: Influence of sodium consumption and associated knowledge on poststroke hypertension in Uganda. 
  • Autoradiographic localization of proline uptake in excitatory hippocampal pathways. 
  • Biochemical and structural changes in cultured heart cells induced by metabolic inhibition. 
  • Blockade of cardiac sodium channels by amitriptyline and diphenylhydantoin. Evidence for two use-dependent binding sites. 
  • Blockade of cardiac sodium channels. Competition between the permeant ion and antiarrhythmic drugs. 
  • Blood levels and urinary excretion of harmine and its metabolites in man and rats. 
  • Burden of early hospitalization after simultaneous liver-kidney transplantation: Results from the US Multicenter SLKT Consortium. 
  • CFTR as a cAMP-dependent regulator of sodium channels. 
  • Calcineurin is essential in cyclosporin A- and FK506-sensitive yeast strains. 
  • Calmodulin mediates Ca2+ sensitivity of sodium channels. 
  • Capsaicin and nicotine both activate a subset of rat trigeminal ganglion neurons. 
  • Cardiac cell toxicity induced by 4-hydroperoxycyclophosphamide is modulated by glutathione. 
  • Cationic selectivity and competition at the sodium entry site in frog skin. 
  • Cell-Specific Actions of the Prostaglandin E-Prostanoid Receptor 4 Attenuating Hypertension: A Dominant Role for Kidney Epithelial Cells Compared With Macrophages. 
  • Changes in children's and adolescents' dietary intake after the implementation of Chile's law of food labeling, advertising and sales in schools: a longitudinal study. 
  • Characteristics of cystine uptake by cultured LLC-PK1 cells. 
  • Characteristics of lysine transport by isolated rat renal cortical tubule fragments. 
  • Characterization and prognostic value of persistent hyponatremia in patients with severe heart failure in the ESCAPE Trial. 
  • Characterization of a Na+/glucose cotransporter cloned from rabbit small intestine. 
  • Characterization of a microcarrier cell culture system for 23Na MR spectroscopy studies. 
  • Characterization of putative amino acid transmitter release from slices of rat dentate gyrus. 
  • Chlorothiazide-induced kaliuresis after adrenalectomy. 
  • Chondrocyte transport and concentration of ascorbic acid is mediated by SVCT2. 
  • Chronic IL-1beta signaling potentiates voltage-dependent sodium currents in trigeminal nociceptive neurons. 
  • Cisplatin-induced changes in sodium, chloride, and urea transport by the frog skin. 
  • Clinical progress note: Indications for and management of sodium-glucose cotransporter-2 (SGLT-2) inhibitors in hospitalized patients. 
  • Cloning and expression of a novel Na(+)-dependent neutral amino acid transporter structurally related to mammalian Na+/glutamate cotransporters. 
  • Combined treatment with vessel dilator and kaliuretic hormone in persons with congestive heart failure. 
  • Comparison of renin-specific IgG and antibody fragments in studies of blood pressure regulation. 
  • Comparison of sodium-glucose cotransporter-2 inhibitors and thiazolidinediones for management of non-alcoholic fatty liver disease: A systematic review and meta-analysis. 
  • Compartmental responses to acute osmotic stress in Leishmania major result in rapid loss of Na+ and Cl-. 
  • Complex binding of L-[3H]glutamate to hippocampal synaptic membranes in the absence of sodium. 
  • Coupled sodium-calcium transport in cultured chick heart cells. 
  • Crystal structure of a concentrative nucleoside transporter from Vibrio cholerae at 2.4 Å. 
  • Cs+ loading reveals Na+-dependent persistent inward current and negative slope resistance region in Aplysia giant neurons. 
  • Current treatment practice and outcomes. Report of the hyponatremia registry. 
  • Cyclosporine A inhibits Ca2+-dependent stimulation of the Na+/H+ antiport in human T cells. 
  • Cystine and lysine transport in cultured human renal epithelial cells. 
  • Dapagliflozin across the range of ejection fraction in patients with heart failure: a patient-level, pooled meta-analysis of DAPA-HF and DELIVER. 
  • Decongestion strategies and renin-angiotensin-aldosterone system activation in acute heart failure. 
  • Defective PTH regulation of sodium-dependent phosphate transport in NHERF-1-/- renal proximal tubule cells and wild-type cells adapted to low-phosphate media. 
  • Deficiency of COX-1 causes natriuresis and enhanced sensitivity to ACE inhibition. 
  • Detection thresholds of potassium salts are related to the molar conductivity of the anion. 
  • Determinants of hypertension in West Africa: contribution of anthropometric and dietary factors to urban-rural and socioeconomic gradients. 
  • Diagnosis and Management of Disorders of Body Tonicity-Hyponatremia and Hypernatremia: Core Curriculum 2020. 
  • Differential regulation of the alpha 2-adrenergic receptor by Na+ and guanine nucleotides. 
  • Disability in patients with end-stage liver disease: Results from the functional assessment in liver transplantation study. 
  • Disentangling the Relationships Between the Renin-Angiotensin-Aldosterone System, Calcium Physiology, and Risk for Kidney Stones. 
  • Disordered salivary immunoglobulin secretion and sodium transport in human chronic graft-versus-host disease. 
  • Disorders of cell volume regulation. I. Effects of inhibition of plasma membrane adenosine triphosphatase with ouabain. 
  • Diuretic complications. 
  • Does a hypertonic saline load predict fluid retention in pacing induced heart failure? 
  • Does smokeless tobacco cause hypertension? 
  • Dopamine neuronal transport kinetics and effects of amphetamine. 
  • Dry electrolyte-balanced heparinized syringes evaluated for determining ionized calcium and other electrolytes in whole blood. 
  • Dual response of lobster muscle fibers to L-glutamate. 
  • Effect of amiloride and some of its analogues of cation transport in isolated frog skin and thin lipid membranes. 
  • Effect of anti-acetylcholine receptor Fab fragments from goats on functional membrane-bound receptor. 
  • Effect of atrial natriuretic factor on brush border membrane transport of phosphate in phosphate-deprived rats. 
  • Effect of chemical modification of dihydrouridine in yeast transfer ribonucleic acid on amino acid acceptor activity and ribosomal binding. 
  • Effect of chemotherapy on uptake of alkali metals by experimental tumors. 
  • Effect of exercise on cation transport in human red cells. 
  • Effect of limited trypsin digestion on the renal Na+-H+ exchanger and its regulation by cAMP-dependent protein kinase. 
  • Effect of low versus high dialysate sodium concentration on blood pressure and endothelial-derived vasoregulators during hemodialysis: a randomized crossover study. 
  • Effect of low vs. high dietary sodium on blood pressure levels in a normotensive Indo-Asian population. 
  • Effect of pH-adjustment of bupivacaine on onset and duration of epidural analgesia in parturients. 
  • Effects of BG9928, an adenosine A₁ receptor antagonist, in patients with congestive heart failure. 
  • Effects of amiloride on pH regulation in canine cardiac Purkinje fibers. 
  • Effects of barbiturates on inhibitory and excitatory responses to applied neurotransmitters in Aplysia. 
  • Effects of cardiotonic steroids on trabecular meshwork cells: search for mediator of ouabain-enhanced outflow facility. 
  • Effects of chemical group specific reagents on sodium entry and the amiloride binding site in frog skin: evidence for separate sites. 
  • Effects of cold exposure and dehydration on renal function in black-tailed prairie dogs. 
  • Effects of converting enzyme inhibition with captopril on renal function in normal and ACTH treated sheep. 
  • Effects of individual components of multiple behavior changes: the PREMIER trial. 
  • Effects of kaliuretic peptide on sodium and water excretion in persons with congestive heart failure. 
  • Effects of potassium and sodium supply on drought-adaptive mechanisms in Eucalyptus grandis plantations. 
  • Effects of stimulation frequency on potassium activity and cell volume in cardiac tissue. 
  • Effects of the DASH diet alone and in combination with exercise and weight loss on blood pressure and cardiovascular biomarkers in men and women with high blood pressure: the ENCORE study. 
  • Effects of the Dietary Approaches to Stop Hypertension (DASH) diet on the pressure-natriuresis relationship. 
  • Effects of two nonsteroidal anti-inflammatory drugs, indomethacin and oxaprozin, on the kidney. 
  • Electron microprobe analysis of human labial gland secretory granules in cystic fibrosis. 
  • Elemental composition of Na pump inhibited rabbit aorta VSM cells by electron probe X-ray microanalysis. 
  • Elemental composition of polyphosphate-containing vacuoles and cytoplasm of Leishmania major. 
  • Elemental microanalysis of organelles in proximal tubules. I. Alterations in transport and metabolism. 
  • Elemental microanalysis of organelles in proximal tubules. II. Effects of oxygen deprivation. 
  • Estimated Long-Term Benefit of Dapagliflozin in Patients With Heart Failure. 
  • Estimated net endogenous acid production and serum bicarbonate in African Americans with chronic kidney disease. 
  • Extending the boundaries of acceptable organ donors: a means of expanding the donor pool for liver transplantation. 
  • Extracellular stimulation of central neurons: influence of stimulus waveform and frequency on neuronal output. 
  • Ezrin binding domain-deficient NHERF attenuates cAMP-mediated inhibition of Na(+)/H(+) exchange in OK cells. 
  • Failure of spermatogenesis in mouse lines deficient in the Na(+)-K(+)-2Cl(-) cotransporter. 
  • Familial hypokalemic periodic paralysis. 
  • Fast 23Na magnetic resonance imaging of acute reperfused myocardial infarction. Potential to assess myocardial viability. 
  • Fetal dexamethasone exposure accelerates development of renal function: relationship to dose, cell differentiation and growth inhibition. 
  • Fibroblast growth factor homologous factor 13 regulates Na+ channels and conduction velocity in murine hearts. 
  • Fibroblast growth factor homologous factors tune arrhythmogenic late NaV1.5 current in calmodulin binding-deficient channels. 
  • Free radicals formed by exposure of pyrimidine solids to sodium atoms: an electron spin resonance study. 
  • FtsZ condensates: an in vitro electron microscopy study. 
  • FtsZ from Escherichia coli, Azotobacter vinelandii, and Thermotoga maritima--quantitation, GTP hydrolysis, and assembly. 
  • Gallbladder Na+/H+ exchange activity is up-regulated prior to cholesterol crystal formation. 
  • Genetic and physiological basis of adaptive salt tolerance divergence between coastal and inland Mimulus guttatus. 
  • HeLa cells express cAMP-inhibitable sodium-dependent phosphate uptake. 
  • How cations change peptide structure. 
  • Hypertonic hyperglycemia progresses to diabetes faster than normotonic hyperglycemia. 
  • Hypotensive effects of clonidine and chlorthalidone. Controlled clinical trial of drugs administered singly and in combination. 
  • Hypoxanthine uptake in isolated rat renal cortical tubule fragments. 
  • Identification and characterization of the sodium-binding site of activated protein C. 
  • Identification of a regulated Na/K/Cl cotransport system in a distal nephron cell line. 
  • Impact of Sodium Humate Coating on Collector Surfaces on Deposition of Polymer-Coated Nanoiron Particles. 
  • Impact of diabetes on the effects of sodium glucose co-transporter-2 inhibitors on kidney outcomes: collaborative meta-analysis of large placebo-controlled trials. 
  • Implications of Alternative Hepatorenal Prognostic Scoring Systems in Acute Heart Failure (from DOSE-AHF and ROSE-AHF). 
  • Improvement in hyponatremia during hospitalization for worsening heart failure is associated with improved outcomes: insights from the Acute and Chronic Therapeutic Impact of a Vasopressin Antagonist in Chronic Heart Failure (ACTIV in CHF) trial. 
  • In situ hybridization evidence for angiotensinogen messenger RNA in the rat proximal tubule. An hypothesis for the intrarenal renin angiotensin system. 
  • Inactivation of the sodium current in squid giant axons by hydrocarbons. 
  • Inappropriate antidiuretic hormone secretion. Occurrence in a patient with Rocky Mountain spotted fever. 
  • Increasing the intracellular Na+ concentration induces differentiation in a pre-B lymphocyte cell line. 
  • Influence of donor base deficit status on recipient outcomes in liver transplantation. 
  • Inhibition of Na+/H+ exchange stimulates CCK secretion in STC-1 cells. 
  • Interaction of signals influencing renin release. 
  • Interindividual variation in serum sodium and longitudinal blood pressure tracking in the Framingham Heart Study. 
  • Introduction: Vasopressin therapy. 
  • Intron retention in mRNA encoding ancillary subunit of insect voltage-gated sodium channel modulates channel expression, gating regulation and drug sensitivity. 
  • Ion beam etching effects in biological microanalysis. 
  • Ion fluxes and differentiation in transformed cell lines. 
  • Ionic content and regulation of cellular volume in rat alveolar type II cells. 
  • Iron accumulation in bronchial epithelial cells is dependent on concurrent sodium transport. 
  • Irreversible stimulation of adenylate cyclase activity of fat cell membranes of phosphoramidate and phosphonate analogs of GTP. 
  • Is the prevalence of dehydration among community-dwelling older adults really low? Informing current debate over the fluid recommendation for adults aged 70+years. 
  • It is strongly recommended to not conduct, fund, or publish research studies that use spot urine samples with estimating equations to assess individuals' sodium (salt) intake in association with health outcomes: a policy statement of the World Hypertension League, International Society of Hypertension and Resolve to Save Lives. 
  • Leishmania donovani amastigotes mobilize organic and inorganic osmolytes during regulatory volume decrease. 
  • Ligand binding to transiently accessible sites: mechanisms for varying apparent binding rates. 
  • Lower serum sodium is associated with increased short-term mortality in hospitalized patients with worsening heart failure: results from the Outcomes of a Prospective Trial of Intravenous Milrinone for Exacerbations of Chronic Heart Failure (OPTIME-CHF) study. 
  • Lower urine sodium predicts longer length of stay in acute heart failure patients: Insights from the ROSE AHF trial. 
  • MELD-Na Accurately Predicts 6-Month Mortality in Patients With Decompensated Cirrhosis: Potential Trigger for Hospice Referral. 
  • Maleylated-BSA induces hydrolysis of PIP2, fluxes of Ca2+, NF-kappaB binding, and transcription of the TNF-alpha gene in murine macrophages. 
  • Management of leukemic hyperleukocytosis with hydration, urinary alkalinization, and allopurinol. Are cranial irradiation and invasive cytoreduction necessary? 
  • Mechanisms of closure of cardiac sodium channels in rabbit ventricular myocytes: single-channel analysis. 
  • Mechanisms of oleoylethanolamide-induced changes in feeding behavior and motor activity. 
  • Mechanisms of use-dependent block of sodium channels in excitable membranes by local anesthetics. 
  • Medical costs of abnormal serum sodium levels. 
  • Melphalan transport, glutathione levels, and glutathione-S-transferase activity in human medulloblastoma. 
  • Membrane properties underlying spontaneous activity of denervated muscle fibres. 
  • Metabolic inhibition-induced transient Ca2+ increase depends on mitochondria in a human proximal renal cell line. 
  • Metabolomic Profiling of the Effects of Dapagliflozin in Heart Failure With Reduced Ejection Fraction: DEFINE-HF. 
  • Microvascular integrity and the time course of myocardial sodium accumulation after acute infarction. 
  • Mitochondrial localization and characterization of 99Tc-SESTAMIBI in heart cells by electron probe X-ray microanalysis and 99Tc-NMR spectroscopy. 
  • Modulating intraventricular conduction through competition of two class 1 antiarrhythmic agents: experience with ethacizin and lidocaine in canine heart. 
  • Molecular characterization and functional expression of the DSC1 channel. 
  • Molecular cloning of the structural gene for exopolygalacturonate lyase from Erwinia chrysanthemi EC16 and characterization of the enzyme product. 
  • Multiparametric magnetic resonance imaging, spectroscopy and multinuclear (²³Na) imaging monitoring of preoperative chemotherapy for locally advanced breast cancer. 
  • Mutational Dissection of Telomeric DNA Binding Requirements of G4 Resolvase 1 Shows that G4-Structure and Certain 3'-Tail Sequences Are Sufficient for Tight and Complete Binding. 
  • Myocardial magnetic resonance imaging contrast agent concentrations after reversible and irreversible ischemic injury. 
  • NHERF-1 uniquely transduces the cAMP signals that inhibit sodium-hydrogen exchange in mouse renal apical membranes. 
  • NMR studies of combined lanthanide shift and relaxation agents for differential characterization of 23Na in a two-compartment model system. 
  • Neurotrophin regulation of ionic currents and cell size depends on cell context. 
  • Neutral proteinase of rabbit skin: an enzyme capable of degrading skin protein and inducing an inflammatory response. 
  • Nitric oxide enhances salt secretion and Na+ sequestration in a mangrove plant, Avicennia marina, through increasing the expression of H+-ATPase and Na+/H+ antiporter under high salinity 
  • Novel Concepts in Nephron Sodium Transport: A Physiological and Clinical Perspective. 
  • Open-label randomized trial of the safety and efficacy of a single dose conivaptan to raise serum sodium in patients with traumatic brain injury. 
  • Ouabain-sensitive Na+-K+ ATPase pumps in cultured human retinal pigment epithelium. 
  • Parathyroid hormone inhibits renal phosphate transport by phosphorylation of serine 77 of sodium-hydrogen exchanger regulatory factor-1. 
  • Penicillin effects on iontophoretic responses in Aplysia californica. 
  • Perioperative anesthetic management for Cesarean section of a parturient with gestational diabetes insipidus. 
  • Persistent tetrodotoxin-sensitive sodium current resulting from U-to-C RNA editing of an insect sodium channel. 
  • Pharmacologic Therapy for Heart Failure with Preserved Ejection Fraction. 
  • Phenamil: an irreversible inhibitor of sodium channels in the toad urinary bladder. 
  • Phorbol esters induce differentiation in a pre-B-lymphocyte cell line by enhancing Na+/H+ exchange. 
  • Plasma atrial natriuretic factor during chronic thoracic inferior vena caval constriction. 
  • Plasma hypertonicity: another marker of frailty? 
  • Polarized localization of voltage-gated Na+ channels is regulated by concerted FGF13 and FGF14 action. 
  • Polypeptides of avian RNA tumor viruses. 1. Isolation and physical and chemical analysis. 
  • Polypeptides of avian RNA tumor viruses. II. Serological characterization. 
  • Population-Level Implications of Sodium-Glucose Cotransporter-2 Inhibitors for Heart Failure With Preserved Ejection Fraction in the US. 
  • Potassium recycling pathways in the human cochlea. 
  • Predictors of postdischarge outcomes from information acquired shortly after admission for acute heart failure: a report from the Placebo-Controlled Randomized Study of the Selective A1 Adenosine Receptor Antagonist Rolofylline for Patients Hospitalized With Acute Decompensated Heart Failure and Volume Overload to Assess Treatment Effect on Congestion and Renal Function (PROTECT) Study. 
  • Predictors of target organ damage in hypertensive blacks and whites. 
  • Prenatal alpha-difluoromethylornithine treatment: effects on postnatal renal growth and function in the rat. 
  • Prescriptions for dietary sodium in patients with chronic kidney disease: how will this shake out? 
  • Probing Na(+)-induced changes in the HIV-1 TAR conformational dynamics using NMR residual dipolar couplings: new insights into the role of counterions and electrostatic interactions in adaptive recognition. 
  • Prostaglandins in severe congestive heart failure. Relation to activation of the renin--angiotensin system and hyponatremia. 
  • Prostanoids and blood pressure: which way is up? 
  • Protein kinase C activates the renal apical membrane Na+/H+ exchanger. 
  • Protein kinase C-alpha regulation of gallbladder Na+ transport becomes progressively more dysfunctional during gallstone formation. 
  • Proton-gated ion channels in mouse bone marrow stromal cells. 
  • RNA editing generates tissue-specific sodium channels with distinct gating properties. 
  • Real-time quantitative elemental analysis and mapping: microchemical imaging in cell physiology. 
  • Regulation of renal Na(+)-H+ exchanger by cAMP-dependent protein kinase. 
  • Regulation of sodium balance and blood pressure by the AT(1A) receptor for angiotensin II. 
  • Regulation of the renal Na+-H+ exchanger. 
  • Relation of the renin-angiotensin-aldosterone system to clinical state in congestive heart failure. 
  • Relationship between admission serum sodium concentration and clinical outcomes in patients hospitalized for heart failure: an analysis from the OPTIMIZE-HF registry. 
  • Relationship of elevated 23Na magnetic resonance image intensity to infarct size after acute reperfused myocardial infarction. 
  • Renal function in the AT1A receptor knockout mouse during normal and volume-expanded conditions. 
  • Renal hemodynamic and tubular transport effects of nitrendipine. 
  • Renin and myocardial infarction in hypertension. 
  • Renin-angiotensin-aldosterone system in nephrotic syndrome. 
  • Revisiting the Role of Ser982 Phosphorylation in Stoichiometry Shift of the Electrogenic Na+/qHCO3- Cotransporter NBCe1. 
  • Robustness of outcomes in trials evaluating sodium-glucose co-transporter 2 inhibitors for heart failure. 
  • Role of Na-K pump potassium regulation and IPSPs in seizures and spreading depression in immature rabbit hippocampal slices. 
  • Role of sodium channel deglycosylation in the genesis of cardiac arrhythmias in heart failure. 
  • Salt and acid studies on canine lingual epithelium. 
  • Seizure-like afterdischarges simulated in a model neuron. 
  • Sequencing and characterization of oligosaccharides using infrared multiphoton dissociation and boronic acid derivatization in a quadrupole ion trap. 
  • Serum electrolyte patterns in end-stage renal disease. 
  • Serum sodium levels and related treatment-emergent adverse events during eslicarbazepine acetate use in adults with epilepsy. 
  • Sex Differences in Characteristics, Outcomes, and Treatment Response With Dapagliflozin Across the Range of Ejection Fraction in Patients With Heart Failure: Insights From DAPA-HF and DELIVER. 
  • Signal discretization: a source of error in histograms of ion channel events. 
  • Silver nanoparticle toxicity is related to coating materials and disruption of sodium concentration regulation. 
  • Sodium Intake and Socioeconomic Status as Risk Factors for Development of Age-Related Cataracts: The Korea National Health and Nutrition Examination Survey. 
  • Sodium and blood pressure: no data dredging, please! 
  • Sodium and water regulation in a patient with cerebral salt wasting. 
  • Sodium bicarb vs sodium chloride, and acetylcysteine vs placebo, did not differ for adverse events after angiography. 
  • Sodium binding site of factor Xa: role of sodium in the prothrombinase complex. 
  • Sodium depresses arterial baroreceptor reflex function in normotensive humans. 
  • Sodium excretion patterns during and following intravenous sodium chloride loads in normal and hypertensive pregnancies. 
  • Sodium regulation of angiotensinogen mRNA expression in rat kidney cortex and medulla. 
  • Sodium-Glucose Co-Transporter-2 Inhibitor Therapy During Anthracycline Treatment: Is There a Role for Cardioprotection? 
  • Sodium-Glucose Cotransporter 2 Inhibitors and Cardiac Remodeling. 
  • Sodium-Glucose Cotransporter 2 Inhibitors in Patients With Heart Failure With Reduced Ejection Fraction: The Heart and Kidney Working Better Together. 
  • Sodium-Glucose Cotransporter-2 Inhibitors: Impact on Atherosclerosis and Atherosclerotic Cardiovascular Disease Events. 
  • Sodium-dependent proline and glutamate uptake by hippocampal synaptosomes during postnatal development. 
  • Sodium-dependent proline uptake in the rat hippocampal formation: association with ipsilateral-commissural projections of CA3 pyramidal cells. 
  • Sodium-glucose co-transporter 2 inhibitors as an early, first-line therapy in patients with heart failure and reduced ejection fraction. 
  • Sodium-glucose co-transporter 2 inhibitors for heart failure: clinical trial efficacy and clinical practice effectiveness. 
  • Sodium-glucose cotransporter 2 inhibitors for heart failure with mildly reduced or preserved ejection fraction: time to deliver implementation. 
  • Sodium-hydrogen exchanger regulatory factor 1 (NHERF-1) transduces signals that mediate dopamine inhibition of sodium-phosphate co-transport in mouse kidney. 
  • Sodium-independent binding of L-[3H]proline to hippocampal synaptic membranes. 
  • Solubilization and reconstitution of renal brush border Na+-H+ exchanger. 
  • Sources of salinity in ground water from Jericho area, Jordan Valley. 
  • Spot urine sodium in acute heart failure: differences in prognostic value on admission and discharge. 
  • Stimulation and inhibition of 1,3-bis(2-chloroethyl)-1-nitrosourea-induced strand breaks and interstrand cross-linking in Col E1 plasmid deoxyribonucleic acid by polyamines and inorganic cations. 
  • Stimulus-response curve of the renal baroreceptor: effect of converting enzyme inhibition and changes in salt intake. 
  • Structure-function of recombinant Na/H exchanger regulatory factor (NHE-RF). 
  • Succinylcholine-induced hyperkalemia: effects of succinylcholine on resting potentials and electrolyte distributions in normal and denervated muscle. 
  • Synaptic mechanism of pentylenetetrazole: selectivity for chloride conductance. 
  • Targeted proteomic profiling of renal Na(+) transporter and channel abundances in angiotensin II type 1a receptor knockout mice. 
  • Temporal trends in risk profiles among patients hospitalized for heart failure. 
  • The DASH diet and sodium reduction improve markers of bone turnover and calcium metabolism in adults. 
  • The Immune System in Hypertension: a Lost Shaker of Salt 2021 Lewis K. Dahl Memorial Lecture. 
  • The Role of Salt Reduction in the Management of Hypertension. 
  • The Role of Sodium and Chloride in Heart Failure: Does It Take Two to Tango? 
  • The Time Is Now for Sodium Glucose Co-Transporter 2 Inhibitors for Heart Failure: A Call to Overcome Clinical Inertia. 
  • The Utility of Basic Metabolic Panel Tests After Total Joint Arthroplasty. 
  • The beta2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange. 
  • The effect of aldosterone on water and electrolyte composition of incubated rat diaphragms. 
  • The effect of cell-free and erythrocyte-containing perfusion in rat livers. 
  • The effect of somatostatin on experimental intestinal obstruction. 
  • The effects of a contrast medium (sodium iothalamate, 80 percent) on left ventricular function. 
  • The feedback regulation of angiotensinogen production by components of the renin-angiotensin system. 
  • The human 5-HT1A receptor expressed in HeLa cells stimulates sodium-dependent phosphate uptake via protein kinase C. 
  • The inextricable role of the kidney in hypertension. 
  • The ionic mechanism of the slow outward current in Aplysia neurons. 
  • The kidney and hypertension: novel insights from transgenic models. 
  • The kidney stone and increased water intake trial in steel workers: results from a pilot study. 
  • The neural basis of sugar preference. 
  • The potential role and rationale for treatment of heart failure with sodium-glucose co-transporter 2 inhibitors. 
  • The predictive value of elevated labial saliva sodium concentration: its relation to labial gland pathology in bone marrow transplant recipients. 
  • The pursuit of truth and beauty. 
  • The specialized junctions of the lens. 
  • Theoretical basis for sodium and potassium MRI of the human heart at 1.5 T. 
  • Theoretical characterization of ion channel blockade: ligand binding to periodically accessible receptors. 
  • Thiazide-Associated Hyponatremia, Report of the Hyponatremia Registry: An Observational Multicenter International Study. 
  • Tolerability and safety barriers to sodium-glucose cotransporter 2 inhibitor initiation in heart failure with reduced ejection fraction. 
  • Transcriptional Dysregulation Underlies Both Monogenic Arrhythmia Syndrome and Common Modifiers of Cardiac Repolarization. 
  • Transport interactions of cystine and dibasic amino acids in isolated rat renal tubules. 
  • Trypsin digestion increases Na(+)-H+ exchange rates in native rabbit brush border membrane. 
  • Type 1 Angiotensin Receptors on CD11c-Expressing Cells Protect Against Hypertension by Regulating Dendritic Cell-Mediated T Cell Activation. 
  • Unconventional serotonergic excitation in Aplysia. 
  • Under pressure: the search for the essential mechanisms of hypertension. 
  • Unitary sodium channels in isolated cardiac myocytes of rabbit. 
  • Urinary sodium excretion is associated with short sleep duration. 
  • Use of the single electrode voltage clamp to perform noise and relaxation studies of acetylcholine-activated channels in Aplysia neurons. 
  • Valproate reduces excitability by blockage of sodium and potassium conductance. 
  • Vascular control of kidney epithelial transporters. 
  • Vascular nutritional correlates of late-life depression. 
  • Vascular type 1 angiotensin receptors control blood pressure by augmenting peripheral vascular resistance in female mice. 
  • Vasopressin receptor antagonists. 
  • Wavelet formation in excitable cardiac tissue: the role of wavefront-obstacle interactions in initiating high-frequency fibrillatory-like arrhythmias. 
  • beta-Adrenergic action on wild-type and KPQ mutant human cardiac Na+ channels: shift in gating but no change in Ca2+:Na+ selectivity. 
  • pH dependence of the Slc4a11-mediated H⁺ conductance is influenced by intracellular lysine residues and modified by disease-linked mutations. 
  • pKa does not predict pH potentiation of sodium channel blockade by lidocaine and W6211 in guinea pig ventricular myocardium. 
  • α1-Syntrophin Variant Identified in Drug-Induced Long QT Syndrome Increases Late Sodium Current. 
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  Keywords of People

  • Erickson, Harold Paul, James B. Duke Distinguished Professor Emeritus, Cell Biology
  • Jabba, Sairam V., Research Scientist, Anesthesiology
  • O'Connor, Christopher Michael, Adjunct Professor in the Department of Medicine, Medicine, Clinical Pharmacology
  • Pitt, Geoffrey Stuart, Adjunct Professor in the Department of Medicine, Medicine, Cardiology
  • Preminger, Glenn Michael, James F. Glenn, M.D. Distinguished Professor of Urology, Surgery, Urology
  • Sparks, Matthew A., Associate Professor of Medicine, Medicine, Nephrology