Somatomedins
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Subject Areas on Research
- Cellular patterns of insulin-like growth factor system gene expression in murine chondrogenesis and osteogenesis.
- DAF-16/FOXO regulates transcription of cki-1/Cip/Kip and repression of lin-4 during C. elegans L1 arrest.
- Differential effects of epidermal growth factor, somatomedin-C/insulin-like growth factor I, and transforming growth factor-beta on porcine granulosa cell deoxyribonucleic acid synthesis and cell proliferation.
- Distinct function of estrogen receptor α in smooth muscle and fibroblast cells in prostate development.
- Embryonic chick cartilage produces its own somatomedin-like peptide to stimulate cartilage growth in vitro.
- Epidermal growth factor stimulates glycogen synthesis in fetal rat hepatocytes: comparison with the glycogenic effects of insulin-like growth factor I and insulin.
- Evidence for a novel insulin-like growth factor (IGF)-dependent protease regulating IGF-binding protein-4 in dermal fibroblasts.
- Food perception without ingestion leads to metabolic changes and irreversible developmental arrest in C. elegans.
- Gli2 and p53 cooperate to regulate IGFBP-3- mediated chondrocyte apoptosis in the progression from benign to malignant cartilage tumors.
- Growth factor-mediated phosphorylation of proapoptotic BAD reduces tubule cell death in vitro and in vivo.
- Growth retardation in the Lesch-Nyhan syndrome.
- Homologous and heterologous growth hormones fail to stimulate avian cartilage growth in vitro.
- Hormonal activation of ornithine decarboxylase in embryonic chick pelvic cartilage.
- Hormonal stimulation of avian embryonic cartilage growth in vitro: histologic and ultrastructural features.
- Identification of late larval stage developmental checkpoints in Caenorhabditis elegans regulated by insulin/IGF and steroid hormone signaling pathways.
- Insulin-like growth factor axis gene polymorphisms and clinical outcomes in pancreatic cancer.
- Insulin-like growth factor axis gene polymorphisms modify risk of pancreatic cancer.
- Insulin/IGF Signaling and Vitellogenin Provisioning Mediate Intergenerational Adaptation to Nutrient Stress.
- N-myc can substitute for insulin-like growth factor signaling in a mouse model of sonic hedgehog-induced medulloblastoma.
- Nutritional regulation of insulin-like growth factor-binding protein gene expression in the ovine fetus and pregnant ewe.
- Pervasive Positive and Negative Feedback Regulation of Insulin-Like Signaling in Caenorhabditis elegans .
- Rare and low-frequency coding variants alter human adult height.
- Regulation and localization of the insulin-like growth factor system in small bowel during altered nutrient status.
- Roles of the lactogens and somatogens in perinatal and postnatal metabolism and growth: studies of a novel mouse model combining lactogen resistance and growth hormone deficiency.
- Somatomedin-C stimulates glycogen synthesis in fetal rat hepatocytes.
- Suppression of immune function in growth hormone-deficient children during treatment with human growth hormone.
- The 25-kilodalton insulin-like growth factor (IGF)-binding protein inhibits both basal and IGF-I-mediated growth of chick embryo pelvic cartilage in vitro.
- The distinct roles of insulin signaling in polyphenic development.
- dbl-1/TGF-β and daf-12/NHR Signaling Mediate Cell-Nonautonomous Effects of daf-16/FOXO on Starvation-Induced Developmental Arrest
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Keywords of People
- Freemark, Michael Scott, Robert C. Atkins, M.D. and Veronica Atkins Distinguished Professor of Pediatrics, in the School of Medicine, Pediatrics, Endocrinology