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Subject Areas on Research
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A CORRELATION BETWEEN THE PROTEIN STRUCTURE AND CATALYTIC ACTIVITY OF ASPARTATE AMINOTRANSFERASE.
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A cellular Trojan Horse for delivery of therapeutic nanoparticles into tumors.
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A kinetic investigation of the interaction of alpha-methylaspartic acid with aspartate aminotransferase.
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A kinetic investigation of the interaction of erythro-beta-hydroxyaspartic acid with aspartate aminotransferase.
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A modified spectrophotometric method appropriate for measuring cholinesterase activity in tissue from carbaryl-treated animals.
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A new purification procedure for bovine milk xanthine oxidase: effect of proteolysis on the subunit structure.
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A novel eye in 'eyeless' shrimp from hydrothermal vents of the Mid-Atlantic Ridge.
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A series of new organic-inorganic molybdenum arsenate complexes based on [(ZnO6)(As3O3)2Mo6O18]4- and [HxAs2Mo6O26](6-x)- clusters as SBUs.
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A simplified method for monitoring the cytochrome aa3 redox state in bilateral cortical areas of unanesthetized cats.
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A temperature jump study of aspartate aminotransferase. a reinvestigation.
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Age-dependent photoionization thresholds of melanosomes and lipofuscin isolated from human retinal pigment epithelium cells.
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Altered ultrastructural morphology of self-aggregated low density lipoproteins: coalescence of lipid domains forming droplets and vesicles.
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An active site tyrosine influences the ability of the dimethyl sulfoxide reductase family of molybdopterin enzymes to reduce S-oxides.
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An investigation of hemopexin redox properties by spectroelectrochemistry: biological relevance for heme uptake.
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An iron tetrahydroporphyrin prosthetic group common to both assimilatory and dissimilatory sulfite reductases.
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An obligately photosynthetic bacterial anaerobe from a deep-sea hydrothermal vent.
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Anaerobic oxidations of myoglobin and hemoglobin by spectroelectrochemistry.
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Analysis of slitless holographic spectrometers implemented by spherical beam volume holograms.
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Assay and detection of the molybdenum cofactor.
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Assessment of the number of nucleotide binding sites on chloroplast coupling factor 1 by the continuous variation method.
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Automated analysis for free and short-chain acylcarnitine in plasma with a centrifugal analyzer.
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Automated dry-film method for phosphorus in serum evaluated.
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Binding of phosphate ligands to ribonuclease A.
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Biological evaluation of some norphenyl analogs of hemicholinium No. 3 and acetyl-seco-hemicholinium No. 3.
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Bis(2,2'-bipyridine)(5,6-epoxy-5,6-dihydro-[1,10]phenanthroline)ruthenium: synthesis and electrochemical and electrochemiluminescence characterization.
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Calcium influx and poststimulus current during early adaptation in Aplysia giant neurons.
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Carbon monoxide-cytochrome interactions in the brain of the fluorocarbon-perfused rat.
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Carbon monoxide-driven reduction of ferric heme and heme proteins.
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Cerebral cytochrome a,a3 inhibition by cyanide in bloodless rats.
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Characterization of a spectrophotometric assay for cAMP phosphodiesterase.
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Characterization of the aqueous iron(III) chelation chemistry of a potential Trojan Horse antimicrobial agent: chelate structure, stability and pH dependent speciation.
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Characterization of the flavoprotein moieties of NADPH-sulfite reductase from Salmonella typhimurium and Escherichia coli. Physicochemical and catalytic properties, amino acid sequence deduced from DNA sequence of cysJ, and comparison with NADPH-cytochrome P-450 reductase.
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Characterization of the molybdenum cofactor of sulfite oxidase, xanthine, oxidase, and nitrate reductase. Identification of a pteridine as a structural component.
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Chemical modification and site-directed mutagenesis of conserved HXXH and PP-loop motif arginines and histidines in the murine bifunctional ATP sulfurylase/adenosine 5'-phosphosulfate kinase.
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Chloroplast coupling factor 1: dependence of rotational correlation time on polypeptide composition.
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Chromogenic assay for phospholipase C from Bacillus cereus.
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Chromophore conformation and the evolution of tertiary structural changes in photoactive yellow protein.
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Comparison of a chemical assay with a tissue-mediated bio-assay for chemical mutagens.
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Conformational changes in the photocycle of Anabaena sensory rhodopsin: absence of the Schiff base counterion protonation signal.
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Conformational changes of beta-lactoglobulin induced by anionic phospholipid.
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Cyclophilin active site mutants have native prolyl isomerase activity with a protein substrate.
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Detection, characterization, and abundance of engineered nanoparticles in complex waters by hyperspectral imagery with enhanced Darkfield microscopy.
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Determination of residual manganese in Mn porphyrin-based superoxide dismutase (SOD) and peroxynitrite reductase mimics.
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Dialyzable calcium measured in 60 micro L of routinely processed serum by continuous-flow analysis with CO2/air segmentation.
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Differential replication of satellite DNA in polyploid tissues of Drosophila virilis.
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Digital image analysis for rapid quantification of total RNA and cDNA for SMART-PCR.
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Direct Optical Imaging of Graphene In Vitro by Nonlinear Femtosecond Laser Spectral Reshaping
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Dispersion multiplexing with broadband filtering for miniature spectrometers.
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Distance dependence of electron transfer in rigid, cofacially compressed, pi-stacked porphyrin-bridge-quinone systems.
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Duchenne muscular dystrophy: detection of deletion carriers by spectrophotometric densitometry.
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Early intracellular events in the replication of bacteriophage T4 deoxyribonucleic acid. VI. Newly synthesized proteins in the T4 protein-deoxyribonucleic acid complex.
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Effect of chemical modification of dihydrouridine in yeast transfer ribonucleic acid on amino acid acceptor activity and ribosomal binding.
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Effect of conformation on the binding of flavins to flavoenzymes.
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Effect of pH and anions on functional properties of hemoglobin from Lemur fulvus fulvus.
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Effect of steady illumination on the binding of carbon monoxide by carboxymethylated cytochrome c.
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Effect of transient hypoxia on oxygenation of the developing rat brain: relationships among haemoglobin saturation, autoregulation of blood flow and mitochondrial redox state.
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Effects of S-nitrosation on oxygen binding by normal and sickle cell hemoglobin.
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Effects of serum creatinine calibration on estimated renal function in african americans: the Jackson heart study.
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Electromagnetic spectroscopy of normal breast tissue specimens obtained from reduction surgeries: comparison of optical and microwave properties.
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Electron microscopic study of the base sequence in nucleic acids. VI. Preparation of ribonucleic acid with marked gauanosine monophosphate nucleotides.
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Electron paramagnetic resonance and optical evidence for interaction between siroheme and Fe4S4 prosthetic groups in complexes of Escherichia coli sulfite reductase hemoprotein with added ligands.
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Evaluation of BA1112 rhabdomyosarcoma oxygenation with microelectrodes, optical spectrophotometry, radiosensitivity, and magnetic resonance spectroscopy.
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Evidence against formation of A23187 dimers and oligomers in solution: photo-induced degradation of Ionophore A23187.
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Evidence for siroheme-Fe4S4 interaction in spinach ferredoxin-sulfite reductase.
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Fluorescence energy transfer measurements in rabbit muscle phosphofructokinase.
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Functional and structural properties of Murex fulvescens hemocyanin: isolation of two different subunits required for reassociation of a molluscan hemocyanin.
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Functional consequences of ligand-linked dissociation in hemoglobin from the sea cucumber Molpadia arenicola.
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Further assessment of an in vitro screen that may help identify organophosphorus pesticides that are more acutely toxic to the young.
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Gamma-L-glutaminyl-3,4-benzoquinone. Structural studies and enzymatic synthesis.
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Genetic diversity of coastal bottlenose dolphins revealed by structurally and functionally diverse hemoglobins.
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HEPATIC ALDEHYDE OXIDASE. 3. THE SUBSTRATE-BINDING SITE.
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HEPATIC ALDEHYDE OXIDASE. II. DIFFERENTIAL INHIBITION OF ELECTRON TRANSFER TO VARIOUS ELECTRON ACCEPTORS.
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Heme-copper oxidases use tunneling pathways.
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Hemoglobin-based oxygen carriers (HBOCs): structural alterations that affect free radical generation.
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Hepatic sulfite oxidase. Congruency in mitochondria of prosthetic groups and activity.
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Hepatic sulfite oxidase. Identification of the molybdenum center as the site of irreversible inactivation by ferricyanide.
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Histologic, nuclear DNA, and human papillomavirus studies of cervical condylomas.
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Human erythrocyte catalase: an improved method of isolation and a reevaluation of reported properties.
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Identification of molybdopterin guanine dinucleotide in formate dehydrogenase from Methanobacterium formicicum.
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Identification of quinone-binding and heme-ligating residues of the smallest membrane-anchoring subunit (QPs3) of bovine heart mitochondrial succinate:ubiquinone reductase.
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In vitro effects of fluoride and bromide on pseudocholinesterase and acetylcholinesterase activities.
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Incorporation of tyrosine and glutamine residues into the soluble guanylate cyclase heme distal pocket alters NO and O2 binding.
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Induction of specific cytochrome P-450 isozymes by methylenedioxyphenyl compounds and antagonism by 3-methylcholanthrene.
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Integrated optical attenuated total reflection spectrometry of aqueous superstrates using prism-coupled polymer waveguides.
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Interaction of photoreactive and fluorescent nucleotides with chloroplast coupling factor 1.
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Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2.
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Intracellular monitoring of experimental respiratory failure. Collaborative Group on Intracellular Monitoring.
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Intraocular pressure effects on optic nerve-head oxidative metabolism measured in vivo.
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Intravitreal clearance of tissue plasminogen activator in the rabbit.
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Investigation of quercetin binding sites on chloroplast coupling factor 1.
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Investigation of the influence on conformational transition of DNA induced by cationic lipid vesicles.
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Isolation and characterization of the major apolipoprotein from chicken high density lipoproteins.
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Isolation and characterization of two group-specific antigens from feline leukemia virus.
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Isolation from the mushroom Agaricus bisporus and chemical synthesis of gamma-L-glutaminyl-4-hydroxybenzene.
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Isolation of the domain containing the molybdenum, iron-sulfur I, and iron-sulfur II centers of chicken liver xanthine dehydrogenase.
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Kinetic and equilibrium studies of the ribonuclease-catalyzed hydrolysis of uridine 2',3'-cyclic phosphate.
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Kinetic mechanism of quinone oxidoreductase 2 and its inhibition by the antimalarial quinolines.
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Kinetic studies of tryptophan synthetase. Interaction of L-serine, indole, and tryptophan with the native enzyme.
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Kinetic studies of tryptophan synthetase. Interaction of substrates with the B subunit.
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Kinetics of iron release from ferric binding protein (FbpA): mechanistic implications in bacterial periplasm-to-cytosol Fe3+ transport.
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Label free colorimetric biosensing using nanoparticles.
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Localization of a cryptic binding site for tenascin on fibronectin.
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Lysolipid incorporation in dipalmitoylphosphatidylcholine bilayer membranes enhances the ion permeability and drug release rates at the membrane phase transition.
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Mapping Tertiary Interactions in Protein Folding Reactions: A Novel Mass Spectrometry- and Chemical Synthesis-Based Approach
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Measuring morphological features using light-scattering spectroscopy and Fourier-domain low-coherence interferometry.
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Mechanism of action of a respiratory inhibitor from the gill tissue of the sporulating common mushroom, Agaricus bisporus.
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Microassay for the photometric quantitation of cell-associated plasminogen activator using a chromogenic tripeptide substrate.
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Mitochondrial Diagnostics: A Multiplexed Assay Platform for Comprehensive Assessment of Mitochondrial Energy Fluxes.
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Mitoxantrone and ametantrone inhibit hydroperoxide-dependent initiation and propagation reactions in fatty acid peroxidation.
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Mn porphyrin-based superoxide dismutase (SOD) mimic, MnIIITE-2-PyP5+, targets mouse heart mitochondria.
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Molecular basis of the biological function of molybdenum. Molybdenum-free sulfite oxidase from livers of tungsten-treated rats.
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Molecular basis of the biological function of molybdenum. Molybdenum-free xanthine oxidase from livers of tungsten-treated rats.
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Molybdopterin guanine dinucleotide: a modified form of molybdopterin identified in the molybdenum cofactor of dimethyl sulfoxide reductase from Rhodobacter sphaeroides forma specialis denitrificans.
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Molybdopterin in carbon monoxide oxidase from carboxydotrophic bacteria.
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Neutron-stimulated emission computed tomography of a multi-element phantom.
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Nitric oxide binding to human ferrihemoglobins cross-linked between either alpha or beta subunits.
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Nitric oxide interactions with cobalamins: biochemical and functional consequences.
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Nitrosylation of manganese(II) tetrakis(N-ethylpyridinium-2-yl)porphyrin: a simple and sensitive spectrophotometric assay for nitric oxide.
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Nonequivalence of the flavin adenine dinucleotide moieties of chicken liver xanthine dehydrogenase.
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Oligonucleotides produced by digestion of bakers' yeast serine transfer ribonucleic acid with specific nucleases.
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On the feasibility of comprehensive high-resolution 3D remote dosimetry.
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On the polyol synthesis of silver nanostructures: glycolaldehyde as a reducing agent.
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On the reaction of ferric heme proteins with nitrite and sulfite.
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Optical and electron paramagnetic resonance spectroscopic studies on purine hydroxylase II from Aspergillus nidulans.
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Optical imaging of epileptiform activity in human neocortex.
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Optimization of expression of human sulfite oxidase and its molybdenum domain.
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Parathyroid hormone secretion and target organ response in experimental acute pancreatitis.
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Partial restoration of normal functional properties in carboxypeptidase A-digested hemoglobin.
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Performance comparison of aperture codes for multimodal, multiplex spectroscopy.
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Phase-lifetime spectrophotometry of deoxycholate-purified bacteriorhodopsin reconstituted into asolectin vesicles.
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Phase-lifetime spectrophotometry of membranes from ion flux mutants of Halobacterium halobium.
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Phosphate ester hydrolysis is catalyzed by a bacterial transferrin: potential implications for in vivo iron transport mechanisms.
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Polypeptides of avian RNA tumor viruses. 1. Isolation and physical and chemical analysis.
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Polypeptides of avian RNA tumor viruses. V. Analysis of the virus core.
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Pressure corrections for CoCl2 as a thermometer in an analytic ultracentrifuge.
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Properties of rabbit muscle phosphofructokinase modified with 7-chloro-4-nitrobenzo-2-oxa-1,3-diazole.
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Protein nitration is mediated by heme and free metals through Fenton-type chemistry: an alternative to the NO/O2- reaction.
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Protonation state of Glu142 differs in the green- and blue-absorbing variants of proteorhodopsin.
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Purification and characterization of a lecithin-D(-)- -hydroxybutyrate dehydrogenase complex.
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Purification and properties of chicken liver xanthine dehydrogenase.
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Purification and properties of the NAD+-dependent (type D) and O2-dependent (type O) forms of rat liver xanthine dehydrogenase.
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Purification and properties of xanthine dehydroganase from Micrococcus lactilyticus.
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Purification of serine-specific transfer ribonucleic acid from bakers' yeast.
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Putative human blue-light photoreceptors hCRY1 and hCRY2 are flavoproteins.
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Quantification of mouse macrophage chemotaxis in vitro: role of C5 for the production of chemotactic activity.
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RNA extraction from human articular cartilage by chondrocyte isolation.
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Reactions of manganese porphyrins with peroxynitrite and carbonate radical anion.
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Reduced nicotinamide adenine dinucleotide phosphate-sulfite reductase of enterobacteria. 3. The Escherichia coli hemoflavoprotein: catalytic parameters and the sequence of electron flow.
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Reduced nicotinamide adenine dinucleotide phosphate-sulfite reductase of enterobacteria. IV. The Escherichia coli hemoflavoprotein: subunit structure and dissociation into hemoprotein and flavoprotein components.
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Reduced nicotinamide adenine dinucleotide phosphate-sulfite reductase of enterobacteria. V. Studies with the Escherichia coli hemoflavoprotein depleted of flavin mononucleotide: distinct roles for the flavin adenine dinucleotide and flavin mononucleotide prosthetic groups in catalysis.
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Reduced nicotinamide adenine dinucleotide phosphate-sulfite reductase of enterobacteria. VI. The reaction of carbon monoxide with the Escherichia coli holoenzyme, the hemoprotein, and free siroheme.
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Reflectance spectroscopy.
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Regulation of translation and transcription of messenger RNA during early embryonic development.
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Relaxation spectra of aspartate transcarbamylase. I. Interaction of 5-bromocytidine triphosphate with native enzyme and regulatory subunit.
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Relaxation spectra of aspartate transcarbamylase. Interaction of the catalytic subunit with carbamyl phosphate, succinate, and L-malate.
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Relaxation spectra of aspartate transcarbamylase. Interaction of the native enzyme with aspartate analogs.
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Relaxation spectra of aspartate transcarbamylase. Interaction of the native enzyme with carbamyl phosphate.
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Relaxation spectra of ribonuclease. VII. The interaction of ribonuclease with uridine 2',3'-cyclic phosphate.
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Resonance Raman spectroscopic characterization of the molybdopterin active site of DMSO reductase.
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Ring-Opening Copolymerization of Maleic Anhydride with Functional Epoxides: Poly(propylene fumarate) Analogues Capable of Post-Polymerization Modification.
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Robust IR-based detection of stable and fractionally populated G-C+ and A-T Hoogsteen base pairs in duplex DNA.
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Role of conserved tyrosine 343 in intramolecular electron transfer in human sulfite oxidase.
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Scanning fiber angle-resolved low coherence interferometry.
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Shape and size control of ZnO nanostructures via a simple solution route.
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Single-target molecule detection with nonbleaching multicolor optical immunolabels.
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Siroheme and sirohydrochlorin. The basis for a new type of porphyrin-related prosthetic group common to both assimilatory and dissimilatory sulfite reductases.
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Siroheme: a new prosthetic group participating in six-electron reduction reactions catalyzed by both sulfite and nitrite reductases.
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Siroheme: a prosthetic group of the Neurospora crassa assimilatory nitrite reductase.
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Site-directed mutagenesis of recombinant sulfite oxidase: identification of cysteine 207 as a ligand of molybdenum.
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Slow oscillations of cytochrome oxidase redox state and blood volume in unanesthetized cat and rabbit cortex. Interhemispheric synchrony.
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Spectrophotometry of b-type cytochromes in rat brain in vivo and in vitro.
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Spectroscopic evidence for anthracenedione antineoplastic agent self-association and complex formation with flavin nucleotides.
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Spectroscopic studies of the molybdenum-containing dimethyl sulfoxide reductase from Rhodobacter sphaeroides f. sp. denitrificans.
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Spot hemoglobin. Studies on the Root effect hemoglobin of a marine teleost.
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Structural and functional properties of cytochrome c oxidases isolated from sharks.
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Structural and metabolic relationship between the molybdenum cofactor and urothione.
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Structural studies of the heme domain of sulfite oxidase: CNBr fragments.
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Structure and phase behavior of lipid suspensions containing phospholipids with covalently attached poly(ethylene glycol).
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Structure of macromolecular aggregates. I. Aggregation-induced conformational changes in polypeptides.
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Studies of aldehyde oxidase by electron paramagnetic resonance spectroscopy. II. Kinetic studies by rapid freezing.
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Studies on the dissociation of flavin adenine dinucleotide from metalloflavoproteins.
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Superoxide dismutase from Streptococcus mutans. Isolation and characterization of two forms of the enzyme.
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Superoxidized states of Escherichia coli sulfite reductase heme protein subunit.
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Synthesis and iron sequestration equilibria of novel exocyclic 3-hydroxy-2-pyridinone donor group siderophore mimics.
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THE ABSORPTION SPECTRA OF IRON-FLAVOPROTEINS.
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The case of the missing NO-hemoglobin: spectral changes suggestive of heme redox reactions reflect changes in NO-heme geometry.
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The effect of a single boranophosphate substitution with defined configuration on the thermal stability and conformation of a DNA duplex.
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The effect of detergents on the reduction of tetrazolium salts.
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The growth mechanism of copper nanowires and their properties in flexible, transparent conducting films.
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The hemoglobin of the crossopterygian fish, Latimeria chalumnae (Smith). Subunit structure and oxygen equilibria.
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The interaction of aspartate aminotransferase with alpha-methylaspartic acid.
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The isolation of 20alpha- and 20beta-hydroxypregn-4-en-3-one from porcine corpora lutea.
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The kinetics of intramolecular distribution of 15N in uric acid following administration of 15N-glycine: preferential labeling of N-(3+9) of uric acid in primary gout and a reappraisal of the "glutamine hypothesis".
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The location of the carotenoid in the B800--850 light-harvesting pigment--protein complex from Rhodopseudomonas capsulata.
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The metabolism of ethynodiol diacetate by rat and human liver.
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The ortho effect makes manganese(III) meso-tetrakis(N-methylpyridinium-2-yl)porphyrin a powerful and potentially useful superoxide dismutase mimic.
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The pterin component of the molybdenum cofactor. Structural characterization of two fluorescent derivatives.
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The site of the redox-linked proton pump in eukaryotic cytochrome c oxidases.
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The state of reduction of molybdopterin in xanthine oxidase and sulfite oxidase.
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Thermodynamic parameters of the alpha-methyl aspartate-aspartate aminotransferase interaction.
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Thin-layer methods for determination of oxygen binding curves of hemoglobin solutions and blood.
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Thrombogenesis: effect of molecular motions, surface order, and hydrophobicity of the polymer interface.
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Total reconstitution of copper-zinc superoxide dismutase.
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Tryptic cleavage of rat liver sulfite oxidase. Isolation and characterization of molybdenum and heme domains.
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Urinary metabolities of harmine in the rat and their inhibition of monoamine oxidase.
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Use of intrinsic optical signals to monitor physiological changes in brain tissue slices.
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Using optical spectroscopy to longitudinally monitor physiological changes within solid tumors.
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Vertical distribution and characterization of aerobic phototrophic bacteria at the Juan de Fuca Ridge in the Pacific Ocean.
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