Mass Spectrometry

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  Subject Areas on Research

  • 3-Aminopyrrolidinone farnesyltransferase inhibitors: design of macrocyclic compounds with improved pharmacokinetics and excellent cell potency. 
  • 3-Hydroxyisovalerylcarnitine in 3-methylcrotonyl-CoA carboxylase deficiency. 
  • A PRDM16-Driven Metabolic Signal from Adipocytes Regulates Precursor Cell Fate. 
  • A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance. 
  • A comprehensive method for extraction and quantitative analysis of sterols and secosteroids from human plasma. 
  • A convenient LC-MS method for assessment of glucose kinetics in vivo with D-[13C6]glucose as a tracer. 
  • A facile synthesis of 1-O-alkyl-2-(R)-hydroxypropane-3-phosphonocholine (lyso-phosphono-platelet activating factor). 
  • A functional proteomics approach to signal transduction. 
  • A gel-free MS-based quantitative proteomic approach accurately measures cytochrome P450 protein concentrations in human liver microsomes. 
  • A mass spectrometry-based probe of equilibrium intermediates in protein-folding reactions. 
  • A metabolic signature of colon cancer initiating cells. 
  • A metabolomic endotype of bioenergetic dysfunction predicts mortality in critically ill patients with acute respiratory failure. 
  • A new face on apoptosis: death-associated protein 3 and PDCD9 are mitochondrial ribosomal proteins. 
  • A new ganglioside of the lactotetraose series, GalNAc-3'-isoLM1, detected in human meconium. 
  • A novel high-performance liquid chromatography/mass spectrometry method for improved selective and sensitive measurement of methotrexate polyglutamation status in human red blood cells. 
  • A novel murine protein with no effect on iron homoeostasis is homologous with transferrin and is the putative inhibitor of carbonic anhydrase. 
  • A novel silver-sulfoethyl cellulose column for purification of ethynyl steroids from biological fluids. 
  • A proteogenomic survey of the Medicago truncatula genome. 
  • A resource of lipidomics and metabolomics data from individuals with undiagnosed diseases. 
  • A stable dimer in the pH-induced equilibrium unfolding of the homo-hexameric enzyme 4-oxalocrotonate tautomerase (4-OT). 
  • A synthetic peptide inhibitor of human immunodeficiency virus replication: correlation between solution structure and viral inhibition. 
  • A truncated progesterone receptor (PR-M) localizes to the mitochondrion and controls cellular respiration. 
  • Acylcarnitines in amniotic fluid: application to the prenatal diagnosis of propionic acidaemia. 
  • Adduct formation in quantitative bioanalysis: effect of ionization conditions on paclitaxel. 
  • Aerosol propellant interference with clinical mass spectrometers. 
  • Agl28 and Agl29 are key components of a Halobacterium salinarum N-glycosylation pathway. 
  • Alkaloids of American species of Erythrina. 
  • Alkaloids of some African, Asian, Polynesian and Australian species of Erythrina. 
  • An auxin gradient and maximum in the Arabidopsis root apex shown by high-resolution cell-specific analysis of IAA distribution and synthesis. 
  • Analysis of "old" proteins unmasks dynamic gradient of cartilage turnover in human limbs. 
  • Analysis of alkylphenol ethoxylate metabolites in the aquatic environment using liquid chromatography-electrospray mass spectrometry 
  • Analysis of biomedical polymer surfaces: polyurethanes and plasma-deposited thin films. 
  • Analysis of phenylthiohydantoin amino acid mixtures for sequencing by thermospray liquid chromatography/mass spectrometry. 
  • Analytical and biological methods for probing the blood-brain barrier. 
  • Anticolon cancer activity of largazole, a marine-derived tunable histone deacetylase inhibitor. 
  • Antigen receptor control of methionine metabolism in T cells. 
  • Antigens from synthetic and natural estrogens: formation by conjugation with protein through a thiopropionic acid link. 
  • Antioxidant responses and oxidative stress in sheepshead minnow larvae exposed to Corexit 9500^® or its component surfactant, DOSS. 
  • Antitumor agents. 172. Synthesis and biological evaluation of novel deacetamidothiocolchicin-7-ols and ester analogs as antitubulin agents. 
  • ApolipoproteinE mimetic peptides improve outcome after focal ischemia. 
  • Application of electrospray ionization mass spectrometry for analysis of haemoglobin adducts with acrylonitrile. 
  • Application of fast atom bombardment with tandem mass spectrometry and liquid chromatography/mass spectrometry to the analysis of acylcarnitines in human urine, blood, and tissue. 
  • Application of high resolution fast atom bombardment and constant B/E ratio linked scanning to the identification and analysis of acylcarnitines in metabolic disease. 
  • Application of ion trap-MS with H/D exchange and QqTOF-MS in the identification of microbial degradates of trimethoprim in nitrifying activated sludge. 
  • Arsenic exposure of rural populations from the Rift Valley of Ethiopia as monitored by keratin in toenails. 
  • Assay for free and total carnitine in human plasma using tandem mass spectrometry. 
  • Assay for protein modification by poly-ADP-ribose in vitro. 
  • Association of a peripheral blood metabolic profile with coronary artery disease and risk of subsequent cardiovascular events. 
  • Association of calcineurin with the COPI protein Sec28 and the COPII protein Sec13 revealed by quantitative proteomics. 
  • Automated analysis for free and short-chain acylcarnitine in plasma with a centrifugal analyzer. 
  • Automated, reproducible, titania-based phosphopeptide enrichment strategy for label-free quantitative phosphoproteomics. 
  • Autophosphorylation in the leucine-rich repeat kinase 2 (LRRK2) GTPase domain modifies kinase and GTP-binding activities. 
  • Basic matrices for the matrix-assisted laser desorption/ionization mass spectrometry of proteins and oligonucleotides. 
  • Benthic and pelagic pathways of methylmercury bioaccumulation in estuarine food webs of the northeast United States. 
  • Benzoic acid glucosinolate esters and other glucosinolates from Arabidopsis thaliana. 
  • Beta2-adrenergic receptor lysosomal trafficking is regulated by ubiquitination of lysyl residues in two distinct receptor domains. 
  • Bioavailability of metalloporphyrin-based SOD mimics is greatly influenced by a single charge residing on a Mn site. 
  • Biochemical mass spectrometry: worth the weight? 
  • Biochemical surrogate markers of hemolysis do not correlate with directly measured erythrocyte survival in sickle cell anemia. 
  • Bioinformatic challenges in targeted proteomics. 
  • Biomimetic, synthetic HDL nanostructures for lymphoma. 
  • Biosynthesis of 2-deoxystreptamine by three crucial enzymes in Streptomyces fradiae NBRC 12773. 
  • Branched-chain amino acid levels are associated with improvement in insulin resistance with weight loss. 
  • Broadband quadrupolar axialization of large multiply charged ions to enhance measurement and minimize conformational restrictions. 
  • Calcineurin-dependent dephosphorylation of the transcription factor CrzA at specific sites controls conidiation, stress tolerance, and virulence of Aspergillus fumigatus. 
  • Capillary Electrophoresis-High Resolution Mass Spectrometry for Measuring In Vivo Arginine Isotope Incorporation in Alzheimer's Disease Mouse Models. 
  • Carbon Nanotube Electron Ionization Source for Portable Mass Spectrometry 
  • Carbon sequestration in Synechococcus Sp.: from molecular machines to hierarchical modeling. 
  • Cardiovascular Metabolomics. 
  • Carnitine homeostasis in the organic acidurias. 
  • Carnitine revisited: potential use as adjunctive treatment in diabetes. 
  • Catabolism of (2E)-4-hydroxy-2-nonenal via ω- and ω-1-oxidation stimulated by ketogenic diet. 
  • Cell cycle dependence of group VIA calcium-independent phospholipase A2 activity. 
  • Cell geometry considerations for the Fourier transform ion cyclotron resonance mass spectrometry remeasurement experiment. 
  • Cell surface glycoproteomic analysis of prostate cancer-derived PC-3 cells. 
  • Cellular response to phase-separated blends of tyrosine-derived polycarbonates. 
  • Ceramide kinase uses ceramide provided by ceramide transport protein: localization to organelles of eicosanoid synthesis. 
  • Certain pairs of ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) synthesize nondegradable forked ubiquitin chains containing all possible isopeptide linkages. 
  • Characterization of Mn(III) complexes of linear and cyclic desferrioxamines as mimics of superoxide dismutase activity. 
  • Characterization of canine intestinal cholecystokinin-58 lacking its carboxyl-terminal nonapeptide. Evidence for similar post-translational processing in brain and gut. 
  • Characterization of cytoskeleton-enriched protein fraction of the trabecular meshwork and ciliary muscle cells. 
  • Characterization of glycosylation profiles of HIV-1 transmitted/founder envelopes by mass spectrometry. 
  • Characterization of host-cell line specific glycosylation profiles of early transmitted/founder HIV-1 gp120 envelope proteins. 
  • Characterization of longitudinal canal tissue in the acorn barnacle Amphibalanus amphitrite. 
  • Characterization of new diagnostic acylcarnitines in patients with beta-ketothiolase deficiency and glutaric aciduria type I using mass spectrometry. 
  • Characterization of new gangliosides of the lactotetraose series in murine xenografts of a human glioma cell line. 
  • Characterization of serum proteins associated with IL28B genotype among patients with chronic hepatitis C. 
  • Characterization of the Vibrio cholerae VolA surface-exposed lipoprotein lysophospholipase. 
  • Chikungunya virus nsP3 & nsP4 interacts with HSP-90 to promote virus replication: HSP-90 inhibitors reduce CHIKV infection and inflammation in vivo. 
  • Chondroitin 4-sulfate covalently cross-links the chains of the human blood protein pre-alpha-inhibitor. 
  • Cleavage and polyadenylation specificity factor 1 (CPSF1) regulates alternative splicing of interleukin 7 receptor (IL7R) exon 6. 
  • Coaxial continuous flow fast atom bombardment in conjunction with tandem mass spectrometry for the analysis of biomolecules. 
  • Combined high-performance liquid chromatographic-continuous-flow fast atom bombardment mass spectrometric analysis of acylcoenzyme A compounds. 
  • Comparative Analysis of Mass-Spectrometry-Based Proteomic Methods for Protein Target Discovery Using a One-Pot Approach. 
  • Comparative Evaluation of MS-based Metabolomics Software and Its Application to Preclinical Alzheimer's Disease. 
  • Comparative analysis of LIN28-RNA binding sites identified at single nucleotide resolution. 
  • Complement-Mediated Regulation of Apolipoprotein E in Cultured Human RPE Cells. 
  • Comprehensive two-dimensional high-performance liquid chromatography for the isolation of overexpressed proteins and proteome mapping. 
  • Concentration and desalting of protein samples for mass spectrometry analysis. 
  • Context-specific effects of fibulin-5 (DANCE/EVEC) on cell proliferation, motility, and invasion. Fibulin-5 is induced by transforming growth factor-beta and affects protein kinase cascades. 
  • Continuous high-frequency dissolved O2/Ar measurements by Equilibrator Inlet Mass Spectrometry (EIMS) 
  • Contribution of various carbon sources toward isoprene biosynthesis in poplar leaves mediated by altered atmospheric CO2 concentrations. 
  • Coordination chemistry of siderophores: thermodynamics and kinetics of iron chelation and release. 
  • Coordination of platinum therapeutic agents to met-rich motifs of human copper transport protein1. 
  • Coupling of capillary zone electrophoresis and capillary liquid chromatography with coaxial continuous-flow fast atom bombardment tandem sector mass spectrometry. 
  • Creatine kinase: essential arginine residues at the nucleotide binding site identified by chemical modification and high-resolution tandem mass spectrometry. 
  • Crystal structure of molybdopterin synthase and its evolutionary relationship to ubiquitin activation. 
  • Crystal-storing histiocytosis: a clinicopathological study of 13 cases. 
  • Current trends in differential expression proteomics: isotopically coded tags. 
  • Decision tree classification of proteins identified by mass spectrometry of blood serum samples from people with and without lung cancer. 
  • Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance. 
  • Delineating signal transduction pathways in smooth muscle through focused proteomics. 
  • Design and application of a data-independent precursor and product ion repository. 
  • Design, synthesis, and evaluation of diarylpyridines and diarylanilines as potent non-nucleoside HIV-1 reverse transcriptase inhibitors. 
  • Detection and characterization of methionine oxidation in peptides by collision-induced dissociation and electron capture dissociation. 
  • Determination of disopyramide and mono-N-desisopropyl-disopyramide in serum by gas-liquid chromatography with nitrogen-selective detection. 
  • Determination of polybrominated diphenyl ethers in indoor dust standard reference materials. 
  • Development of a novel method for measuring in vivo breast epithelial cell proliferation in humans. 
  • Development of an on-line preconcentration method for the analysis of pathogenic lipopolysaccharides using capillary electrophoresis-electrospray mass spectrometry. Application to small colony isolates. 
  • Diagnosis of mitochondrial trifunctional protein deficiency in a blood spot from the newborn screening card by tandem mass spectrometry and DNA analysis. 
  • Dicranin, an antimicrobial and 15-lipoxygenase inhibitor from the moss Dicranum scoparium. 
  • Dietary regulation of catabolic disposal of 4-hydroxynonenal analogs in rat liver. 
  • Differentiation of isomeric acylcarnitines using tandem mass spectrometry. 
  • Direct analysis of traditional Chinese medicines using Surface-Enhanced Raman Scattering (SERS). 
  • Direct liquid chromatography determination of the reactive imine SJG-136 (NSC 694501). 
  • Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers. 
  • Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects. 
  • Discovery of novel cyclophilin A ligands using an H/D exchange- and mass spectrometry-based strategy. 
  • Diversity in prokaryotic glycosylation: an archaeal-derived N-linked glycan contains legionaminic acid. 
  • Domain structure and DNA binding regions of beta protein from bacteriophage lambda. 
  • Dual role of glutathione in modulating camptothecin activity: depletion potentiates activity, but conjugation enhances the stability of the topoisomerase I-DNA cleavage complex. 
  • Durhamycin A, a potent inhibitor of HIV Tat transactivation. 
  • ENU mutagenesis identifies mice with mitochondrial branched-chain aminotransferase deficiency resembling human maple syrup urine disease. 
  • ERK-dependent proteasome degradation of Txnip regulates thioredoxin oxidoreductase activity. 
  • Early-life experience decreases drug-induced reinstatement of morphine CPP in adulthood via microglial-specific epigenetic programming of anti-inflammatory IL-10 expression. 
  • Effects of S-nitrosation on oxygen binding by normal and sickle cell hemoglobin. 
  • Electron capture dissociation mass spectrometry in characterization of post-translational modifications. 
  • Elucidating structural and molecular mechanisms of β-arrestin-biased agonism at GPCRs via MS-based proteomics. 
  • Elucidating the Molecular Composition of Cartilage by Proteomics. 
  • Enantiomeric propanolamines as selective N-methyl-D-aspartate 2B receptor antagonists. 
  • Enhanced TOF-SIMS imaging of a micropatterned protein by stable isotope protein labeling. 
  • Enhanced method performance due to a shorter chromatographic run-time in a liquid chromatography-tandem mass spectrometry assay for paclitaxel. 
  • Ethylmalonic aciduria: an organic acidemia with CNS involvement and vasculopathy. 
  • Evaluation of 3-methylcrotonyl-CoA carboxylase deficiency detected by tandem mass spectrometry newborn screening. 
  • Evidence against formation of A23187 dimers and oligomers in solution: photo-induced degradation of Ionophore A23187. 
  • Evidence for CRHR1 in multiple sclerosis using supervised machine learning and meta-analysis in 12,566 individuals. 
  • Evidence that Gsta4 modifies susceptibility to skin tumor development in mice and humans. 
  • Expression, purification, and identification of associated proteins of the full-length hCDK12/CyclinK complex. 
  • Extensive diversity in circadian regulation of plasma lipids and evidence for different circadian metabolic phenotypes in humans. 
  • Extracellular matrix proteins and carcinoembryonic antigen-related cell adhesion molecules characterize pancreatic duct fluid exosomes in patients with pancreatic cancer. 
  • Extraction and identification by mass spectrometry of undecaprenyl diphosphate-MurNAc-pentapeptide-GlcNAc from Escherichia coli. 
  • Extraction parameters for metabolomics from cultured cells. 
  • False-positive rate determination of protein target discovery using a covalent modification- and mass spectrometry-based proteomics platform. 
  • From the Cover: Arsenite Uncouples Mitochondrial Respiration and Induces a Warburg-like Effect in Caenorhabditis elegans. 
  • Functional specialization of beta-arrestin interactions revealed by proteomic analysis. 
  • G Protein-Coupled Receptor Endocytosis Confers Uniformity in Responses to Chemically Distinct Ligands. 
  • Gain of glucose-independent growth upon metastasis of breast cancer cells to the brain. 
  • Ganglioside mapping of a human medulloblastoma xenograft. 
  • Gene deletions leading to a reduction in the number of cyclopentane rings in Sulfolobus acidocaldarius tetraether lipids. 
  • Generation and quality control of lipidomics data for the alzheimer's disease neuroimaging initiative cohort. 
  • Genetic polymorphisms of metabolic enzymes and the pharmacokinetics of indapamide in Taiwanese subjects. 
  • Genomic insights into the atopic eczema-associated skin commensal yeast Malassezia sympodialis. 
  • Geochemical evidence for possible natural migration of Marcellus Formation brine to shallow aquifers in Pennsylvania. 
  • Getting more from less: algorithms for rapid protein identification with multiple short peptide sequences. 
  • Giant cell interstitial pneumonia in patients without hard metal exposure: analysis of 3 cases and review of the literature. 
  • Global whole-cell FTICR mass spectrometric proteomics analysis of the heat shock response in the radioresistant bacterium Deinococcus radiodurans. 
  • Glutamine Metabolism Regulates Proliferation and Lineage Allocation in Skeletal Stem Cells. 
  • Glutaric acidemia, type I, missed by newborn screening in an infant with dystonia following promethazine administration. 
  • Glutathione-associated cis-diamminedichloroplatinum(II) metabolism and ATP-dependent efflux from leukemia cells. Molecular characterization of glutathione-platinum complex and its biological significance. 
  • Glycosylation site-specific analysis of clade C HIV-1 envelope proteins. 
  • Growth Differentiation Factor-15-Induced Contractile Activity and Extracellular Matrix Production in Human Trabecular Meshwork Cells. 
  • H/D exchange- and mass spectrometry-based strategy for the thermodynamic analysis of protein-ligand binding. 
  • HLA-B*1502-bound peptides: implications for the pathogenesis of carbamazepine-induced Stevens-Johnson syndrome. 
  • Halobacterium salinarum NRC-1 PeptideAtlas: toward strategies for targeted proteomics and improved proteome coverage. 
  • Hemoglobin Raleigh (beta1 valine replaced by acetylalanine). Structural and functional characterization. 
  • Hepatic monoacylglycerol acyltransferase: ontogeny and characterization of an activity associated with the chick embryo. 
  • Hepatitis C virus selectively perturbs the distal cholesterol synthesis pathway in a genotype-specific manner. 
  • High levels of agreement between clinic-based ethyl glucuronide (EtG) immunoassays and laboratory-based mass spectrometry. 
  • High performance liquid chromatography-mass spectrometry assay for polymyxin B1 and B2 in human plasma. 
  • High spatial resolution proteomic comparison of the brain in humans and chimpanzees. 
  • High-affinity inhibitors of dihydrofolate reductase: antimicrobial and anticancer activities of 7,8-dialkyl-1,3-diaminopyrrolo[3,2-f]quinazolines with small molecular size. 
  • High-level 2H/13C/15N labeling of proteins for NMR studies. 
  • High-level misincorporation of lysine for arginine at AGA codons in a fusion protein expressed in Escherichia coli. 
  • Human UDP-galactose 4'-epimerase (GALE) is required for cell-surface glycome structure and function. 
  • Human cytidine triphosphate synthetase 1 interacting proteins. 
  • Hydrogen/deuterium exchange- and protease digestion-based screening assay for protein-ligand binding detection. 
  • Identification and Quantitation of Coding Variants and Isoforms of Pulmonary Surfactant Protein A. 
  • Identification and localization of the fatty acid modification in ghrelin by electron capture dissociation. 
  • Identification in rat bile of glutathione conjugates of fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether, a nephrotoxic degradate of the anesthetic agent sevoflurane. 
  • Identification of N-acylphosphatidylserine molecules in eukaryotic cells. 
  • Identification of Proteins Bound to Dengue Viral RNA In Vivo Reveals New Host Proteins Important for Virus Replication. 
  • Identification of a chloroform-soluble membrane miniprotein in Escherichia coli and its homolog in Salmonella typhimurium. 
  • Identification of an elaborate complex mediating postsynaptic inhibition. 
  • Identification of four proteins from the small subunit of the mammalian mitochondrial ribosome using a proteomics approach. 
  • Identification of impurities in erythromycin by liquid chromatography-mass spectrometric detection. 
  • Identification of novel quaternary domain interactions in the Hsp90 chaperone, GRP94. 
  • Identification of phenylpropionylcarnitine, a new metabolite of phenylpropionic acid, in a patient with medium chain acyl-CoA dehydrogenase deficiency. 
  • Identification of self-lipids presented by CD1c and CD1d proteins. 
  • Identification of the carotenoid present in the B-800-850 antenna complex from Rhodopseudomonas capsulata as that which responds electrochromically to transmembrane electric fields. 
  • Identification of ubiquitination sites on the X-linked inhibitor of apoptosis protein. 
  • Immunomodulatory lipid mediator profiling of cerebrospinal fluid following surgery in older adults. 
  • Improved Detection of Invasive Pulmonary Aspergillosis Arising during Leukemia Treatment Using a Panel of Host Response Proteins and Fungal Antigens. 
  • In vitro metabolism of the COX-2 inhibitor DFU, including a novel glutathione adduct rearomatization. 
  • Inactivation of 4-oxalocrotonate tautomerase by 2-oxo-3-pentynoate. 
  • Increased in vitro phenol-soluble modulin production is associated with soft tissue infection source in clinical isolates of methicillin-susceptible Staphylococcus aureus. 
  • Inflammatory cytokines and cellular metabolites as synovial fluid biomarkers of posttraumatic ankle arthritis. 
  • Insulin resistance is associated with a metabolic profile of altered protein metabolism in Chinese and Asian-Indian men. 
  • International Ring Trial of a High Resolution Targeted Metabolomics and Lipidomics Platform for Serum and Plasma Analysis. 
  • Intravenous and oral alfentanil as in vivo probes for hepatic and first-pass cytochrome P450 3A activity: noninvasive assessment by use of pupillary miosis. 
  • Intravenous fluid resuscitation is associated with septic endothelial glycocalyx degradation. 
  • Investigating the Sensitivity of NAD+-dependent Sirtuin Deacylation Activities to NADH. 
  • Ion beam etching effects in biological microanalysis. 
  • Ion microanalysis of cells. 
  • Ion mobility derived collision cross sections to support metabolomics applications. 
  • Iron chelation equilibria, redox, and siderophore activity of a saccharide platform ferrichrome analogue. 
  • Isocoproporphyrin: nuclear-magnetic-resonance-and mass-spectral methods for the determination of porphyrin structure. 
  • Isolation from the mushroom Agaricus bisporus and chemical synthesis of gamma-L-glutaminyl-4-hydroxybenzene. 
  • Isolation of human trophoblastic extracellular vesicles and characterization of their cargo and antiviral activity. 
  • Isolation, gas chromatography-mass spectrometry, and structures of new alkaloids from Erythrina folkersii Krukoff and Moldenke and Erythrina salviiflora Krukoff and Barneby. 
  • JMJD6 cleaves MePCE to release positive transcription elongation factor b (P-TEFb) in higher eukaryotes. 
  • L-carnitine enhances excretion of propionyl coenzyme A as propionylcarnitine in propionic acidemia. 
  • L-carnitine therapy in isovaleric acidemia. 
  • LC-UV/MS methods for the analysis of prochelator-boronyl salicylaldehyde isonicotinoyl hydrazone (BSIH) and its active chelator salicylaldehyde isonicotinoyl hydrazone (SIH). 
  • LC/MS analysis of cardiolipins in substantia nigra and plasma of rotenone-treated rats: Implication for mitochondrial dysfunction in Parkinson's disease. 
  • LRRK2 and Rab10 coordinate macropinocytosis to mediate immunological responses in phagocytes. 
  • Largazole pharmacokinetics in rats by LC-MS/MS. 
  • Layers of regulation of cell-cycle gene expression in the budding yeast Saccharomyces cerevisiae. 
  • Lipid diversity among botulinum neurotoxin-producing clostridia. 
  • Lipid modification gives rise to two distinct Haloferax volcanii S-layer glycoprotein populations. 
  • Lipidomic Analysis of Clostridium cadaveris and Clostridium fallax. 
  • Location and role of free cysteinyl residues in the Sindbis virus E1 and E2 glycoproteins. 
  • Lysine glutarylation is a protein posttranslational modification regulated by SIRT5. 
  • Lysolipid incorporation in dipalmitoylphosphatidylcholine bilayer membranes enhances the ion permeability and drug release rates at the membrane phase transition. 
  • Lysophosphatidic Acid Induces ECM Production via Activation of the Mechanosensitive YAP/TAZ Transcriptional Pathway in Trabecular Meshwork Cells. 
  • Manganese-porphyrin reactions with lipids and lipoproteins. 
  • Mapping bacterial glycolipid complexity using capillary electrophoresis and electrospray mass spectrometry. 
  • Mass spectrometry as a readout of protein structure and function. 
  • Mass spectrometry of nucleic acids: the promise of matrix-assisted laser desorption-ionization (MALDI) mass spectrometry. 
  • Mass spectrometry- and lysine amidination-based protocol for thermodynamic analysis of protein folding and ligand binding interactions. 
  • Mass spectrometry. 
  • Matching isotopic distributions from metabolically labeled samples. 
  • Maternal metabolic profiling to assess fetal gestational age and predict preterm delivery: a two-centre retrospective cohort study in the US. 
  • Maximum entropy reconstructions of dynamic signaling networks from quantitative proteomics data. 
  • Measurements of secondary organic aerosol from oxidation of cycloalkenes, terpenes, and m-xylene using an Aerodyne aerosol mass spectrometer. 
  • Measuring acetyl-CoA and acetylated histone turnover in vivo: Effect of a high fat diet. 
  • Mechanistic Investigation of cPMP Synthase in Molybdenum Cofactor Biosynthesis Using an Uncleavable Substrate Analogue. 
  • Mechanistic and mutational studies of Escherichia coli molybdopterin synthase clarify the final step of molybdopterin biosynthesis. 
  • Mechanistic aspects of carbon monoxide formation from volatile anesthetics. 
  • Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency: diagnosis by acylcarnitine analysis in blood. 
  • Medium-chain acyl-CoA dehydrogenase deficiency. 
  • Metabolic profiles predict adverse events after coronary artery bypass grafting. 
  • Metabolism and distribution of norethynodrel in pregnant and nonpregnant mice. 
  • Metabolites and diabetes remission after weight loss. 
  • Metabolomic profiling for the identification of novel biomarkers and mechanisms related to common cardiovascular diseases: form and function. 
  • Metabolomic profiling identifies complex lipid species and amino acid analogues associated with response to weight loss interventions. 
  • Metabolomics in early Alzheimer's disease: identification of altered plasma sphingolipidome using shotgun lipidomics. 
  • Metabolomics in premature labor: a novel approach to identify patients at risk for preterm delivery. 
  • Metabolomics, pathway regulation, and pathway discovery. 
  • Metabolomics: A Primer. 
  • Metastatic castration-resistant prostate cancer reveals intrapatient similarity and interpatient heterogeneity of therapeutic kinase targets. 
  • Methodologies for the characterization, identification and quantification of S-nitrosylated proteins. 
  • Microchemical analysis of selenium in otoliths of two West Virginia fishes captured near mountaintop removal coal mining operations. 
  • Mixed peptide sequencing and the FASTF/FASTS algorithms. 
  • Modification of cysteine 111 in human Cu,Zn-superoxide dismutase. 
  • Modified SH2 domain to phototrap and identify phosphotyrosine proteins from subcellular sites within cells. 
  • Monitoring protein conformational changes and dynamics using stable-isotope labeling and mass spectrometry. 
  • Monomeric yeast frataxin is an iron-binding protein. 
  • Multiple ligand-specific conformations of the β2-adrenergic receptor. 
  • Multiplex detection of disease biomarkers using SERS molecular sentinel-on-chip. 
  • Mutants resistant to LpxC inhibitors by rebalancing cellular homeostasis. 
  • NADPH:quinone oxidoreductase 1 regulates host susceptibility to ozone via isoprostane generation. 
  • Naming and counting disorders (conditions) included in newborn screening panels. 
  • Nanoscale separations combined with tandem mass spectrometry. 
  • Nanotechnologies and regenerative medical approaches for space and terrestrial medicine. 
  • Nasopharyngeal Protein Biomarkers of Acute Respiratory Virus Infection. 
  • Native nonmuscle myosin II stability and light chain binding in Drosophila melanogaster. 
  • Nephrotoxicity of sevoflurane compound A [fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether] in rats: evidence for glutathione and cysteine conjugate formation and the role of renal cysteine conjugate beta-lyase. 
  • New Insight of Common Regulatory Pathways in Human Trabecular Meshwork Cells in Response to Dexamethasone and Prednisolone Using an Integrated Quantitative Proteomics: SWATH and MRM-HR Mass Spectrometry. 
  • New Strategies and Challenges in Lung Proteomics and Metabolomics. An Official American Thoracic Society Workshop Report. 
  • New developments in proteomics. 
  • New mass spectrometric assay for angiotensin-converting enzyme 2 activity. 
  • New techniques for imaging and analyzing lung tissue. 
  • Newborn screening for Krabbe disease in New York State: the first eight years' experience. 
  • Newborn screening for lysosomal storage disorders. 
  • Newborn tandem mass spectroscopy screening for adenosine deaminase deficiency. 
  • Nitric oxide reduces NADPH oxidase 5 (Nox5) activity by reversible S-nitrosylation. 
  • Non-enzymatically derived minor lipids found in Escherichia coli lipid extracts. 
  • Nonparametric estimation and inference for polytomous discrimination index. 
  • Nontarget Screening with High Resolution Mass Spectrometry in the Environment: Ready to Go? 
  • Norethynodrel metabolites in human plasma and urine. 
  • Novel HIV-1 Non-nucleoside Reverse Transcriptase Inhibitor Agents: Optimization of Diarylanilines with High Potency against Wild-Type and Rilpivirine-Resistant E138K Mutant Virus. 
  • O-Alkyl dioleoylphosphatidylcholinium compounds: the effect of varying alkyl chain length on their physical properties and in vitro DNA transfection activity. 
  • Oncogene-specific activation of tyrosine kinase networks during prostate cancer progression. 
  • Opposing effects of cancer-type-specific SPOP mutants on BET protein degradation and sensitivity to BET inhibitors. 
  • Osteoarthritic chondrocyte-secreted morphogens induce chondrogenic differentiation of human mesenchymal stem cells. 
  • Overproduction of alpha chains provides a proton-insensitive component to the bluefish hemoglobin system. 
  • Oxidative stress and covalent modification of protein with bioactive aldehydes. 
  • Oxygenated norethindrone derivatives from incubation with beagle liver. Structure, synthesis, and biological activity. 
  • Oxylipid Profile of Low-Dose Aspirin Exposure: A Pharmacometabolomics Study. 
  • Painting proteins with covalent labels: what's in the picture? 
  • Parental dietary seleno-L-methionine exposure and resultant offspring developmental toxicity. 
  • Phagocytic cells synthesize 19-nor-10-keto-25-hydroxyvitamin D3, a metabolite that may induce differentiation of the human monoblastic cell line U937. 
  • Pharmacokinetic Analysis of a Novel Human EGFRvIII:CD3 Bispecific Antibody in Plasma and Whole Blood Using a High-Resolution Targeted Mass Spectrometry Approach. 
  • Phenotypic mapping of metabolic profiles using self-organizing maps of high-dimensional mass spectrometry data. 
  • Phosphatidylcholine composition of pulmonary surfactant from terrestrial and marine diving mammals. 
  • Phosphoproteome analysis of capacitated human sperm. Evidence of tyrosine phosphorylation of a kinase-anchoring protein 3 and valosin-containing protein/p97 during capacitation. 
  • Phosphoproteome analysis reveals regulatory sites in major pathways of cardiac mitochondria. 
  • Phosphorylation by protein kinase CK2 changes the DNA binding properties of the human chromatin protein DEK. 
  • Phosphorylation of Src by phosphoinositide 3-kinase regulates beta-adrenergic receptor-mediated EGFR transactivation. 
  • Phosphorylation of c-Abl by protein kinase Pak2 regulates differential binding of ABI2 and CRK. 
  • Phosphorylation of phosphatase inhibitor-2 at centrosomes during mitosis. 
  • Photodegradation pathways of nonabrominated diphenyl ethers, 2-ethylhexyltetrabromobenzoate and di(2-ethylhexyl)tetrabromophthalate: identifying potential markers of photodegradation. 
  • Plasma acylcarnitines are associated with physical performance in elderly men. 
  • Polycyclic aromatic hydrocarbons in the atmospheres of Titan and Jupiter. 
  • Polyene antibiotics. IV. Structure of chainin. 
  • Prediction of Residual Risk by Ceramide-Phospholipid Score in Patients With Stable Coronary Heart Disease on Optimal Medical Therapy. 
  • Predictors of urinary flame retardant concentration among pregnant women. 
  • Preliminary evidence of effects of potassium chloride on a metabolomic path to diabetes and cardiovascular disease. 
  • Presence of the protein-glycosaminoglycan-protein covalent cross-link in the inter-alpha-inhibitor-related proteinase inhibitor heavy chain 2/bikunin. 
  • Prion protein paralog doppel protein interacts with alpha-2-macroglobulin: a plausible mechanism for doppel-mediated neurodegeneration. 
  • ProSAAS-derived peptides are regulated by cocaine and are required for sensitization to the locomotor effects of cocaine. 
  • Probing conformational changes in human DNA topoisomerase IIα by pulsed alkylation mass spectrometry. 
  • Probing the oligomeric structure of an enzyme by electrospray ionization time-of-flight mass spectrometry. 
  • Proceedings: Measurement of endogenous steroid levels in human breast tumours by mass fragmentography. 
  • Processive post-translational modification. Vitamin K-dependent carboxylation of a peptide substrate. 
  • Prognostic Implications of Long-Chain Acylcarnitines in Heart Failure and Reversibility With Mechanical Circulatory Support. 
  • Progressive Rod-Cone Degeneration (PRCD) Protein Requires N-Terminal S-Acylation and Rhodopsin Binding for Photoreceptor Outer Segment Localization and Maintaining Intracellular Stability. 
  • Proposed high-risk screening protocol for Fabry disease in patients with renal and vascular disease. 
  • Protein expression profiles in pancreatic adenocarcinoma compared with normal pancreatic tissue and tissue affected by pancreatitis as detected by two-dimensional gel electrophoresis and mass spectrometry. 
  • Protein kinetic signatures of the remodeling heart following isoproterenol stimulation. 
  • Protein modification by deamidation indicates variations in joint extracellular matrix turnover. 
  • Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex. 
  • Proteins of purified Epstein-Barr virus. 
  • Proteome analyses using accurate mass and elution time peptide tags with capillary LC time-of-flight mass spectrometry. 
  • Proteome analysis by mass spectrometry. 
  • Proteome-Wide Structural Biology: An Emerging Field for the Structural Analysis of Proteins on the Proteomic Scale. 
  • Proteome-wide muscle protein fractional synthesis rates predict muscle mass gain in response to a selective androgen receptor modulator in rats. 
  • Proteomic analysis of S-nitrosylation and denitrosylation by resin-assisted capture. 
  • Proteomic analysis of desmosomes reveals novel components required for epidermal integrity. 
  • Proteomic analysis of endometrium from fertile and infertile patients suggests a role for apolipoprotein A-I in embryo implantation failure and endometriosis. 
  • Proteomic analysis of the NOS2 interactome in human airway epithelial cells. 
  • Proteomic identification of unique photoreceptor disc components reveals the presence of PRCD, a protein linked to retinal degeneration. 
  • Proteomics in prostate cancer. 
  • Protonation of the neutral repeats of the RNA polymerase II CTD. 
  • Proximity labeling for investigating protein-protein interactions. 
  • Purification and characterization of a luminal cholecystokinin-releasing factor from rat intestinal secretion. 
  • Purification of outer membrane vesicles from Pseudomonas aeruginosa and their activation of an IL-8 response. 
  • Purification, characterization, and structural elucidation of the active moiety of the previously called "suppressor activating factor (SAF)". 
  • Quality of potent Mn porphyrin-based SOD mimics and peroxynitrite scavengers for pre-clinical mechanistic/therapeutic purposes. 
  • Quantifying ceramide kinetics in vivo using stable isotope tracers and LC-MS/MS. 
  • Quantitation of dolastatin-10 using HPLC/electrospray ionization mass spectrometry: application in a phase I clinical trial. 
  • Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane. 
  • Quantitative assay of free and total carnitine using tandem mass spectrometry. 
  • Quantitative determinants of aerobic glycolysis identify flux through the enzyme GAPDH as a limiting step. 
  • Quantitative label-free phosphoproteomics strategy for multifaceted experimental designs. 
  • Quantitative proteomics approach for identifying protein-drug interactions in complex mixtures using protein stability measurements. 
  • RRmix: A method for simultaneous batch effect correction and analysis of metabolomics data in the absence of internal standards. 
  • Rabbit and human liver contain a novel pentacyclic triterpene ester with acyl-CoA: cholesterol acyltransferase inhibitory activity. 
  • Rapid detection of argininosuccinic aciduria and citrullinuria by fast atom bombardment and tandem mass spectrometry. 
  • Rapid diagnosis of homocystinuria and other hypermethioninemias from newborns' blood spots by tandem mass spectrometry. 
  • Rapid diagnosis of maple syrup urine disease in blood spots from newborns by tandem mass spectrometry. 
  • Rapid diagnosis of phenylketonuria by quantitative analysis for phenylalanine and tyrosine in neonatal blood spots by tandem mass spectrometry. 
  • Rapid identification of protein phosphatase 1-binding proteins by mixed peptide sequencing and data base searching. Characterization of a novel holoenzymic form of protein phosphatase 1. 
  • Rapid optimization of enzyme substrates using defined substrate mixtures. 
  • Rapid separation and characterization of protein and peptide mixtures using 1.5 microns diameter non-porous silica in packed capillary liquid chromatography/mass spectrometry. 
  • Rare disorders of metabolism with elevated butyryl- and isobutyryl-carnitine detected by tandem mass spectrometry newborn screening. 
  • Re-patterning of skeletal muscle energy metabolism by fat storage-inducing transmembrane protein 2. 
  • Reaction of N-acylhomoserine lactones with hydroxyl radicals: rates, products, and effects on signaling activity. 
  • Real-time in vivo proteomic identification of novel kinase substrates in smooth muscle. 
  • Real-time monitoring of the gas phase reactions of a single ion population using the remeasurement experiment in Fourier transform ion cyclotron resonance mass spectrometry. 
  • Recent advances in the analysis of polychlorinated biphenyls in environmental and biological media. 
  • Recognition of medium-chain acyl-CoA dehydrogenase deficiency in asymptomatic siblings of children dying of sudden infant death or Reye-like syndromes. 
  • Red Blood Cells and Lipoproteins: Important Reservoirs and Transporters of Polyphenols and Their Metabolites. 
  • Reduced levels of human apoE4 protein in an animal model of cognitive impairment. 
  • Relationships between personal, indoor, and outdoor exposures to trace elements in PM(2.5). 
  • Remeasurement of electrosprayed proteins in the trapped ion cell of a Fourier transform ion cyclotron resonance mass spectrometer. 
  • Renaturation and partial peptide sequencing of mitogen-activated protein kinase (MAP kinase) activator from rabbit skeletal muscle. 
  • Resolving Adeno-Associated Viral Particle Diversity With Charge Detection Mass Spectrometry. 
  • SILAC-pulse proteolysis: A mass spectrometry-based method for discovery and cross-validation in proteome-wide studies of ligand binding. 
  • SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production. 
  • SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. 
  • Selected metastable peak monitoring: a new specific technique in quantitative gas chromatography mass spectrometry. 
  • Selenium-binding protein-1 in smooth muscle cells is downregulated in a rhesus monkey model of chronic allograft nephropathy. 
  • Sensitive analysis of [D-Pen2,5]enkephalin in rat serum by capillary electrophoresis and laser-induced fluorescence detection. 
  • Sensitive quantitation of chromium-DNA adducts by inductively coupled plasma mass spectrometry with a direct injection high-efficiency nebulizer. 
  • Sequencing and characterization of oligosaccharides using infrared multiphoton dissociation and boronic acid derivatization in a quadrupole ion trap. 
  • Seroconversion on preexposure prophylaxis: a case report with segmental hair analysis for timed adherence determination. 
  • Simple assay for proteases based on aggregation of stimulus-responsive polypeptides. 
  • Simultaneous assessment of drug interactions with low- and high-extraction opioids: application to parecoxib effects on the pharmacokinetics and pharmacodynamics of fentanyl and alfentanil. 
  • Simultaneous determination of alpha-aminoadipic semialdehyde, piperideine-6-carboxylate and pipecolic acid by LC-MS/MS for pyridoxine-dependent seizures and folinic acid-responsive seizures. 
  • Simultaneous proteomic profiling of four different growth states of human fibroblasts, using amine-reactive isobaric tagging reagents and tandem mass spectrometry. 
  • Site-specific conjugation of a temperature-sensitive polymer to a genetically-engineered protein. 
  • Skyline for Small Molecules: A Unifying Software Package for Quantitative Metabolomics. 
  • Slow histidine H/D exchange protocol for thermodynamic analysis of protein folding and stability using mass spectrometry. 
  • Small ubiquitin-like modifier 3-modified proteome regulated by brain ischemia in novel small ubiquitin-like modifier transgenic mice: putative protective proteins/pathways. 
  • Spatiotemporal Transformation in the Alkaloid Profile of Pinus Roots in Response to Mycorrhization. 
  • Sphingolipidomics: high-throughput, structure-specific, and quantitative analysis of sphingolipids by liquid chromatography tandem mass spectrometry. 
  • Stable isotope labeling strategy for protein-ligand binding analysis in multi-component protein mixtures. 
  • StableIsotope Labeling with Amino Acids in Cell Culture (SILAC)-based strategy for proteome-wide thermodynamic analysis of protein-ligand binding interactions. 
  • Static secondary ion mass spectrometric investigation of the surface chemistry of organic plasma-deposited films created from oxygen-containing precursors. 3. Multivariate statistical modeling. 
  • Static secondary-ion mass spectrometric investigation of the surface structure of organic plasma-deposited films prepared from stable-isotope-labeled precursors. 1. Carbonyl precursors. 
  • Stereoselective determination of methadone and the primary metabolite EDDP in human plasma by automated on-line extraction and liquid chromatography mass spectrometry. 
  • Stoichiometries of protein-protein/DNA binding and conformational changes for the transition-state regulator AbrB measured by pseudo cell-size exclusion chromatography-mass spectrometry. 
  • Structural basis of O-GlcNAc recognition by mammalian 14-3-3 proteins. 
  • Structural basis of salicylic acid perception by Arabidopsis NPR proteins. 
  • Structural characterization of a molybdopterin precursor. 
  • Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis. 
  • Structural insight and characterization of human Twinkle helicase in mitochondrial disease. 
  • Structure Database and In Silico Spectral Library for Comprehensive Suspect Screening of Per- and Polyfluoroalkyl Substances (PFASs) in Environmental Media by High-resolution Mass Spectrometry. 
  • Structure and DNA-binding traits of the transition state regulator AbrB. 
  • Structure and biological activity of (-)-[3H]dihydroalprenolol, a radioligand for studies of beta-adrenergic receptors. 
  • Structure and biosynthesis of free lipid A molecules that replace lipopolysaccharide in Francisella tularensis subsp. novicida. 
  • Structure of the F-spondin domain of mindin, an integrin ligand and pattern recognition molecule. 
  • Structure of the ubiquitin-binding zinc finger domain of human DNA Y-polymerase eta. 
  • Substrate Selectivity of Lysophospholipid Transporter LplT Involved in Membrane Phospholipid Remodeling in Escherichia coli. 
  • Successful diagnosis of HIBCH deficiency from exome sequencing and positive retrospective analysis of newborn screening cards in two siblings presenting with Leigh's disease. 
  • Succinylated octopamine ascarosides and a new pathway of biogenic amine metabolism in Caenorhabditis elegans. 
  • Switching of α-Catenin From Epithelial to Neuronal Type During Lens Epithelial Cell Differentiation. 
  • Synthesis and characterization of SERS gene probe for BRCA-1 (breast cancer). 
  • Synthesis of new 2'-deoxy-2'-fluoro-4'-azido nucleoside analogues as potent anti-HIV agents. 
  • Synthesis of prodrug candidates: conjugates of amino acid with nucleoside boranophosphate. 
  • Synthesis, structure, and antibiotic activity of aryl-substituted LpxC inhibitors. 
  • Systemic exposure to fluticasone MDI delivered through antistatic chambers. 
  • TBK1 Limits mTORC1 by Promoting Phosphorylation of Raptor Ser877. 
  • Tandem mass spectrometry: a new method for acylcarnitine profiling with potential for neonatal screening for inborn errors of metabolism. 
  • Targeted Mass Spectrometry-Based Approach for Protein-Ligand Binding Analyses in Complex Biological Mixtures Using a Phenacyl Bromide Modification Strategy. 
  • Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection. 
  • Tenascin-C is an innate broad-spectrum, HIV-1-neutralizing protein in breast milk. 
  • The DEXH protein product of the DHX36 gene is the major source of tetramolecular quadruplex G4-DNA resolving activity in HeLa cell lysates. 
  • The G2019S mutation in LRRK2 imparts resiliency to kinase inhibition. 
  • The GTPase activating factor for transducin in rod photoreceptors is the complex between RGS9 and type 5 G protein beta subunit. 
  • The Listeria monocytogenes PASTA Kinase PrkA and Its Substrate YvcK Are Required for Cell Wall Homeostasis, Metabolism, and Virulence. 
  • The binding of SLE autoantibodies to mitochondria. 
  • The cellular lipids of Romboutsia. 
  • The effect of genotype on methotrexate polyglutamate variability in juvenile idiopathic arthritis and association with drug response. 
  • The field ionization spectra of some natural coumarins. 
  • The intestinal glucose-apelin cycle controls carbohydrate absorption in mice. 
  • The isotopic composition of anthropogenic boron and its potential impact on the environment. 
  • The kinetics of intramolecular distribution of 15N in uric acid following administration of 15N-glycine: preferential labeling of N-(3+9) of uric acid in primary gout and a reappraisal of the "glutamine hypothesis". 
  • The large subunit of the mammalian mitochondrial ribosome. Analysis of the complement of ribosomal proteins present. 
  • The metabotropic glutamate receptor subtype 5 antagonist fenobam is analgesic and has improved in vivo selectivity compared with the prototypical antagonist 2-methyl-6-(phenylethynyl)-pyridine. 
  • The oral iron chelator deferiprone protects against iron overload-induced retinal degeneration. 
  • The outer surface lipoprotein VolA mediates utilization of exogenous lipids by Vibrio cholerae. 
  • The pterin component of the molybdenum cofactor. Structural characterization of two fluorescent derivatives. 
  • The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present. 
  • The structure of a molybdopterin precursor. Characterization of a stable, oxidized derivative. 
  • The structure of the molybdenum cofactor. Characterization of di-(carboxamidomethyl)molybdopterin from sulfite oxidase and xanthine oxidase. 
  • The ubiquitin-conjugating enzyme (E2) Ube2w ubiquitinates the N terminus of substrates. 
  • The unanticipated loss of SO2 from sulfonamides in collision-induced dissociation. 
  • Thermodynamic Analysis of the Geldanamycin-Hsp90 Interaction in a Whole Cell Lysate Using a Mass Spectrometry-Based Proteomics Approach. 
  • Thermospray liquid chromatography/mass spectrometry for the analysis of L-carnitine and its short-chain acyl derivatives. 
  • Top-down quantitative proteomics identified phosphorylation of cardiac troponin I as a candidate biomarker for chronic heart failure. 
  • Total body skeletal muscle mass: estimation by creatine (methyl-d3) dilution in humans. 
  • Total testosterone assays in women with polycystic ovary syndrome: precision and correlation with hirsutism. 
  • Towards prenatal biomonitoring in North Carolina: assessing arsenic, cadmium, mercury, and lead levels in pregnant women. 
  • Transitions from functionalization to fragmentation reactions of laboratory secondary organic aerosol (SOA) generated from the OH oxidation of alkane precursors. 
  • Ubiquitin fold modifier 1 (UFM1) and its target UFBP1 protect pancreatic beta cells from ER stress-induced apoptosis. 
  • Understanding the Role of Aggregation in the Broad Absorption Bands of Eumelanin 
  • Urinary biomarkers of oxidative status in a clinical model of oxidative assault. 
  • Urinary tetrabromobenzoic acid (TBBA) as a biomarker of exposure to the flame retardant mixture Firemaster® 550. 
  • Using dynamic programming to create isotopic distribution maps from mass spectra. 
  • Utility of discovery approach using proteomics to create a biomarker profile for coronary microvascular dysfunction. 
  • Validation of the association between a branched chain amino acid metabolite profile and extremes of coronary artery disease in patients referred for cardiac catheterization. 
  • Valproylcarnitine: a novel drug metabolite identified by fast atom bombardment and thermospray liquid chromatography-mass spectrometry. 
  • Variations in IBD (ACAD8) in children with elevated C4-carnitine detected by tandem mass spectrometry newborn screening. 
  • What is mzXML good for? 
  • [A transformylation reaction--transfer of an N-formyl residue to amino acids and peptides in nucleophilic groups--as a side reaction of peptide synthesis]. 
  • [Atypical course of a multiple acyl-CoA-dehydrogenase deficiency]. 
  • [Endogenous inhibitors of the specific binding of benzodiazepines in the cerebral cortex]. 
  • alpha(2)-Macroglobulin from rheumatoid arthritis synovial fluid: functional analysis defines a role for oxidation in inflammation. 
  • p38-MAPK induced dephosphorylation of alpha-tropomyosin is associated with depression of myocardial sarcomeric tension and ATPase activity. 
  • trans-2-Phenylcyclopropylamine is a mechanism-based inactivator of the histone demethylase LSD1. 
• 

  Keywords of People

  • Erickson, Harold Paul, James B. Duke Distinguished Professor Emeritus, Cell Biology
  • Gehm, Michael E., Professor of Electrical and Computer Engineering, Electrical and Computer Engineering
  • Grimsrud, Paul, Assistant Professor in Medicine, Medicine, Endocrinology, Metabolism, and Nutrition
  • Guan, Ziqiang, Research Professor in Biochemistry, Biochemistry
  • Hirschey, Matthew, Associate Professor of Medicine, Cell Biology
  • Luftig, Micah Alan, Professor of Molecular Genetics and Microbiology, Cell Biology
  • Nielsen, Karen Cristina, Associate Professor of Anesthesiology, Anesthesiology, Ambulatory
  • Oas, Terrence Gilbert, Professor of Biochemistry, Biochemistry
  • Patz Jr., Edward F., James and Alice Chen Distinguished Professor of Radiology, Pathology
  • Soderling, Scott Haydn, George Barth Geller Distinguished Professor of Molecular Biology, Cell Biology
  • Vengosh, Avner, Nicholas Distinguished Professor of Environmental Quality, Nicholas Institute-Energy Initiative
  • Yancy Jr., William Samuel, Professor of Medicine, Medicine, General Internal Medicine
  • Young, Sarah Phyllis, Professor of Pediatrics, Pediatrics, Medical Genetics