Spermine
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Subject Areas on Research
- A fine line between molecular umbrella transport and ionophoric activity.
- A simplified method for isocratic HPLC analysis of polyamines.
- Bacterial endotoxin stimulates macrophages to release HMGB1 partly through CD14- and TNF-dependent mechanisms.
- Changes in regional polyamine profiles in rat brains after transient cerebral ischemia (single versus repetitive ischemia): evidence for release of polyamines from injured neurons.
- Direct binding properties of conantokins to native N-methyl-d-aspartate receptors.
- Direct tris(2,2'-bipyridyl)ruthenium (II) electrochemiluminescence detection of polyamines separated by capillary electrophoresis.
- Disrupted spermine homeostasis: a novel mechanism in polyglutamine-mediated aggregation and cell death.
- Effect of spermine on membranolytic effect of vitamin A in rats.
- Effects of beta-endorphin on ornithine decarboxylase in tissues of developing rats: a potential role for this endogenous neuropeptide in the modulation of tissue growth.
- Erythrocyte polyamine levels during intravenous feeding of patients with colorectal carcinoma.
- Ex vivo spermine dialdehyde treatment prevents lethal GVHD in a murine bone marrow transplantation model.
- Increased expression of NR2A subunit does not alter NMDA-evoked responses in cultured fetal trisomy 16 mouse hippocampal neurons.
- Inhibition of NMDA-induced currents by conantokin-G and conantokin-T in cultured embryonic murine hippocampal neurons.
- Initial testing (stage 1) of the polyamine analog PG11047 by the pediatric preclinical testing program.
- Keap1 modification and nuclear accumulation in response to S-nitrosocysteine.
- Kinetic and mechanistic characterization of NMDA receptor antagonism by replacement and truncation variants of the conantokin peptides.
- Modulation of inositol phospholipid metabolism by polyamines.
- Nitric oxide stimulates Nrf2 nuclear translocation in vascular endothelium.
- Ornithine decarboxylase and polyamines in tissues of the neonatal rat: effects of alpha-difluoromethylornithine, a specific, irreversible inhibitor of ornithine decarboxylase.
- Phase 1 study of N(1),N(11)‑diethylnorspermine (DENSPM) in patients with advanced hepatocellular carcinoma.
- Polyamine changes in reversible cerebral ischemia.
- Polyamine metabolism in carcinoma of the oral cavity compared with adjacent and normal oral mucosa.
- Polyamine metabolism in experimental brain tumors of rat.
- Polyamine metabolism in gliomas.
- Polyamine metabolism in transient focal ischemia of rat brain.
- Polyamine stimulation of protein phosphatase-2A from rat liver using a non-protein phosphoester substrate.
- Polyamines antagonize N-methyl-D-aspartate-evoked depolarizations, but reduce Mg2+ block.
- Polyamines as endogenous modulators of the N-methyl-D-aspartate receptor.
- Polyamines in brain and heart of the neonatal rat: effects of inhibitors of ornithine decarboxylase and spermidine synthase.
- Polyamines in cerebral ischemia.
- Purification, characterization, and structural elucidation of the active moiety of the previously called "suppressor activating factor (SAF)".
- Regional profile of polyamines in reversible cerebral ischemia of Mongolian gerbils.
- Relationship of erythrocyte polyamine levels and growth rate of transplantable tumors in rats.
- Spermine dialdehyde, a novel ex vivo purging agent for both allogenic and autologous bone marrow transplantations.
- Spermine. A regulator of mitochondrial calcium cycling.
- Stimulation and inhibition of 1,3-bis(2-chloroethyl)-1-nitrosourea-induced strand breaks and interstrand cross-linking in Col E1 plasmid deoxyribonucleic acid by polyamines and inorganic cations.
- The role of pre-ischaemic application of the nitric oxide donor spermine/nitric oxide complex in enhancing flap survival in a rat model.
- Toxic effects of maternal methadone administration on cardiac development in the neonatal rat: potential participation of altered polyamine levels in growth impairment.
- Transgenic manipulation of the metabolism of polyamines in poplar cells.