Spine

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  Subject Areas on Research

  • 313 Impact of Intraoperative Steroids on Postoperative Infection Rates and Length of Hospital Stay: A Study of 1200 Spine Surgery Patients. 
  • 315 Race as a Predictor of Postoperative Hospital Readmission After Spine Surgery. 
  • A Novel Weave Tether Technique for Proximal Junctional Kyphosis Prevention in 71 Adult Spinal Deformity Patients: A Preliminary Case Series Assessing Early Complications and Efficacy. 
  • A benefit of spinal manipulation as adjunctive therapy for acute low-back pain: a stratified controlled trial. 
  • A mechanism for gene-environment interaction in the etiology of congenital scoliosis. 
  • A prospective, multi-institutional comparative effectiveness study of lumbar spine surgery in morbidly obese patients: does minimally invasive transforaminal lumbar interbody fusion result in superior outcomes? 
  • A survey-based study of wrong-level lumbar spine surgery: the scope of the problem and current practices in place to help avoid these errors. 
  • Abnormal vertebral segmentation and the notch signaling pathway in man. 
  • Actin Out: Regulation of the Synaptic Cytoskeleton. 
  • Acute heart failure during spinal surgery in a boy with Duchenne muscular dystrophy. 
  • Acute spinal ligament disruption: MR imaging with anatomic correlation. 
  • Adding thoracic fusion levels in Lenke 5 curves: risks and benefits. 
  • Adjunct and minimally invasive techniques for the diagnosis and treatment of vertebral tumors. 
  • Alignment Risk Factors for Proximal Junctional Kyphosis and the Effect of Lower Thoracic Junctional Tethers for Adult Spinal Deformity. 
  • An application of generalizability theory to study a physical performance measure in Parkinson's disease. 
  • An image-guided technique for planning and verification of supine craniospinal irradiation. 
  • Apparatus-dependent dosimetric differences in spine stereotactic body radiotherapy. 
  • Are extra-spinal symptoms associated with quality of life in patients with axial spondyloarthritis? A 1-year follow-up study. 
  • Assessing agreement with repeated measures for random observers. 
  • Assessment of Adult Spinal Deformity Complication Timing and Impact on 2-Year Outcomes Using a Comprehensive Adult Spinal Deformity Classification System. 
  • Assessment of Patient Outcomes and Proximal Junctional Failure Rate of Patients with Adult Spinal Deformity Undergoing Caudal Extension of Previous Spinal Fusion. 
  • Automatic localization of target vertebrae in spine surgery: clinical evaluation of the LevelCheck registration algorithm. 
  • Basis for spinal manipulative therapy: a physical therapist perspective. 
  • Beyond opioid patient-controlled analgesia: a systematic review of analgesia after major spine surgery. 
  • Bone density and amenorrhea in ballet dancers are related to a decreased resting metabolic rate and lower leptin levels. 
  • Brief Report: Macrophage Activation in HIV-Infected Adolescent Males Contributes to Differential Bone Loss by Sex: Adolescent Trials Network Study 021. 
  • Cell Saver for Adult Spinal Deformity Surgery Reduces Cost. 
  • Cerebellar hemorrhage after spinal surgery: report of two cases and literature review. 
  • Cervical sagittal deformity develops after PJK in adult thoracolumbar deformity correction: radiographic analysis utilizing a novel global sagittal angular parameter, the CTPA. 
  • Cervical spine injuries in pediatric athletes: mechanisms and management. 
  • Chronic axial compression of the mouse tail segment induces MRI bone marrow edema changes that correlate with increased marrow vasculature and cellularity. 
  • Classifications for adult spinal deformity and use of the Scoliosis Research Society-Schwab Adult Spinal Deformity Classification. 
  • Clinical and radiographic evaluation of the adult spinal deformity patient. 
  • Clinical and radiographic parameters associated with best versus worst clinical outcomes in minimally invasive spinal deformity surgery. 
  • Commentary: Optimizing Visualization in Endoscopic Spine Surgery. 
  • Comparing and Contrasting the Clinical Utility of Sagittal Spine Alignment Classification Frameworks: Roussouly Versus SRS-Schwab. 
  • Comparison of Complications and Clinical and Radiographic Outcomes Between Nonobese and Obese Patients with Adult Spinal Deformity Undergoing Minimally Invasive Surgery. 
  • Comparison of three predictive scoring systems for morbidity in oncological spine surgery. 
  • Comparison of visually estimated blood loss with direct hemoglobin measurement in multilevel spine surgery. 
  • Comprehensive study of back and leg pain improvements after adult spinal deformity surgery: analysis of 421 patients with 2-year follow-up and of the impact of the surgery on treatment satisfaction. 
  • Concerning the inferior portion of the spinal radiotherapy field for malignancies that disseminate via the cerebrospinal fluid. 
  • Congenitally absent C-7 pedicle presenting as a jumped locked facet. Case illustration. 
  • Consensus building in metastatic spine disease. 
  • Coronal plane spinal malalignment and Parkinson's disease: prevalence and associations with disease severity. 
  • Correlation of higher preoperative American Society of Anesthesiology grade and increased morbidity and mortality rates in patients undergoing spine surgery. 
  • Cost-Utility Analysis of rhBMP-2 Use in Adult Spinal Deformity Surgery. 
  • Counseling Guidelines for Anticipated Postsurgical Improvements in Pain, Function, Mental Health, and Self-image for Different Types of Adult Spinal Deformity. 
  • Current applications of robotics in spine surgery: a systematic review of the literature. 
  • De Novo Mutations in SON Disrupt RNA Splicing of Genes Essential for Brain Development and Metabolism, Causing an Intellectual-Disability Syndrome. 
  • Defective molybdopterin biosynthesis: clinical heterogeneity associated with molybdenum cofactor deficiency. 
  • Defining Spino-Pelvic Alignment Thresholds: Should Operative Goals in Adult Spinal Deformity Surgery Account for Age? 
  • Defining Usage and Clinical Outcomes Following Perioperative Fresh Frozen Plasma and Platelet Administration in Spine Surgery Patients. 
  • Defining a Surgical Invasiveness Threshold for Increased Risk of a Major Complication Following Adult Spinal Deformity Surgery. 
  • Depression as an independent predictor of postoperative delirium in spine deformity patients undergoing elective spine surgery. 
  • Descriptive Epidemiology of Spinal Meningiomas in the United States. 
  • Development of a preoperative predictive model for major complications following adult spinal deformity surgery. 
  • Development of a straight vertebrate body axis. 
  • Development, validation and characterization of a novel mouse model of Adynamic Bone Disease (ABD). 
  • Developmental anomalies of the skin. 
  • Diet and bone status in amenorrheic runners. 
  • Digital image-intensifier radiography at a level I trauma center. 
  • Does Achieving Global Spinal Alignment Lead to Higher Patient Satisfaction and Lower Disability in Adult Spinal Deformity? 
  • Does MIS Surgery Allow for Shorter Constructs in the Surgical Treatment of Adult Spinal Deformity? 
  • Does facility volume influence survival in patients with primary malignant bone tumors of the vertebral column? A comparative cohort study. 
  • Dynamic changes of the pelvis and spine are key to predicting postoperative sagittal alignment after pedicle subtraction osteotomy: a critical analysis of preoperative planning techniques. 
  • Editorial: Incremental cost-effectiveness of adult spinal deformity surgery. 
  • Effect of Body Habitus on Radiation Dose During CT Fluoroscopy-Guided Spine Injections. 
  • Effect of Prone Positional Apparatus on the Occurrence of Acute Kidney Injury After Spine Surgery. 
  • Emerging Technologies in Spinal Surgery. 
  • Evaluation of complication rates of pediatric spinal procedures in which a polyethylene glycol sealant was used. 
  • Exercise to improve spinal flexibility and function for people with Parkinson's disease: a randomized, controlled trial. 
  • Explanatory multivariate modeling for disability, pain, and claims in patients with spine pain via a physical therapy direct access model of care. 
  • Extensive spinal epidural abscess treated with "apical laminectomies" and irrigation of the epidural space: report of 2 cases. 
  • Extraneural Glioblastoma Multiforme Vertebral Metastasis. 
  • Extreme lateral interbody fusion for the treatment of adult degenerative scoliosis. 
  • FRODO pulse sequences: a new means of eliminating motion, flow, and wraparound artifacts. 
  • Fracture Rates and Bone Density Among Postmenopausal Veteran and Non-Veteran Women From the Women's Health Initiative. 
  • Functional and evolutionary aspects of axial stability in euarchontans and other mammals. 
  • Grasping primate origins. 
  • Growth-preserving instrumentation in early-onset scoliosis patients with multi-level congenital anomalies. 
  • Guideline summary review: an evidence-based clinical guideline for the diagnosis and treatment of low back pain. 
  • Hardware failure in patients with metastatic cancer to the spine. 
  • Hippocrates' influence on the origins of neurosurgery. 
  • Hospital Readmission Within 2 Years Following Adult Thoracolumbar Spinal Deformity Surgery: Prevalence, Predictors, and Effect on Patient-derived Outcome Measures. 
  • Hyponatremia and syndrome of inappropriate antidiuretic hormone secretion in adult spinal surgery. 
  • Impact of Affective Disorders on Recovery of Baseline Function in Patients Undergoing Spinal Surgery: A Single Institution Study of 275 Patients. 
  • Impact of Neurapheresis System on Intrathecal Cerebrospinal Fluid Dynamics: A Computational Fluid Dynamics Study. 
  • Impact of age on the likelihood of reaching a minimum clinically important difference in 374 three-column spinal osteotomies: clinical article. 
  • Impact of anesthesia on transcranial electric motor evoked potential monitoring during spine surgery: a review of the literature. 
  • Impact of growth friendly interventions on spine and pulmonary outcomes of patients with spinal muscular atrophy. 
  • Impact of spinopelvic alignment on decision making in deformity surgery in adults: A review. 
  • Importance of Spinal Alignment in Primary and Metastatic Spine Tumors. 
  • Improving Quality and Consistency in NRG Oncology Radiation Therapy Oncology Group 0631 for Spine Radiosurgery via Knowledge-Based Planning. 
  • Incidence and risk factors of postoperative neurologic decline after complex adult spinal deformity surgery: results of the Scoli-RISK-1 study. 
  • Incidence of Congenital Spinal Abnormalities Among Pediatric Patients and Their Association With Scoliosis and Systemic Anomalies. 
  • Independent Association Between Preoperative Cognitive Status and Discharge Location After Surgery: A Strategy to Reduce Resource Use After Surgery for Deformity. 
  • Independent Associations With 30- and 90-Day Unplanned Readmissions After Elective Lumbar Spine Surgery: A National Trend Analysis of 144 123 Patients. 
  • Independent Predictors of 30-Day Perioperative Deep Vein Thrombosis in 1346 Consecutive Patients After Spine Surgery. 
  • Inflammatory and dysplastic lesions involving the spine. 
  • Initial experience with the use of an expandable titanium cage as a vertebral body replacement in patients with tumors of the spinal column: a report of 95 patients. 
  • Intermediate-term clinical and radiographic outcomes with less invasive adult spinal deformity surgery: patients with a minimum follow-up of 4 years. 
  • Intraoperative electrophysiological monitoring in spine surgery. 
  • Joint hypermobility is not positively associated with prevalent multiple joint osteoarthritis: a cross-sectional study of older adults. 
  • Kickstand Rod Technique for Correcting Coronal Imbalance in Adult Scoliosis: 2-Dimensional Operative Video. 
  • Kinematic characterization of standing reach: comparison of younger vs. older subjects. 
  • Lateral Thoracolumbar Listhesis as an Independent Predictor of Disability in Adult Scoliosis Patients: Multivariable Assessment Before and After Surgical Realignment. 
  • Less invasive surgery for treating adult spinal deformities: ceiling effects for deformity correction with 3 different techniques. 
  • Looking through a crystal ball--the question of primarily fusing to the pelvis in adult degenerative scoliosis. 
  • Loss of col8a1a function during zebrafish embryogenesis results in congenital vertebral malformations. 
  • Loss of tubulin deglutamylase CCP1 causes infantile-onset neurodegeneration. 
  • MR parameters for imaging titanium spinal instrumentation. 
  • Magnitude of spinal muscle damage is not statistically associated with exercise-induced low back pain intensity. 
  • Magnitude, Location, and Factors Related to Regional and Global Sagittal Alignment Change in Long Adult Deformity Constructs: Report of 183 Patients With 2-Year Follow-up. 
  • Methadone and Ketamine: Boosting Benefits and Still More to Learn. 
  • Minimally Invasive Advances in Deformity. 
  • Minimally invasive spine surgery. 
  • Molecular and phenotypic characterization of a new mouse insertional mutation that causes a defect in the distal vertebrae of the spine. 
  • Multicenter validation of a formula predicting postoperative spinopelvic alignment. 
  • Muscle Flap Closures in Spine Surgery: Predictors of Usage Patterns and Factors Associated With Postoperative Complications From the NSQIP Database. 
  • Myelographic Techniques for the Detection of Spinal CSF Leaks in Spontaneous Intracranial Hypotension. 
  • National trends in vertebral augmentation procedures for the treatment of vertebral compression fractures. 
  • Natural history of spinopelvic alignment differs from symptomatic deformity of the spine. 
  • Nitrous oxide anesthesia and plasma homocysteine in adolescents. 
  • Normal fetal pelvis: important factors for morphometric characterization with US. 
  • Notochord vacuoles are lysosome-related organelles that function in axis and spine morphogenesis. 
  • Notochordal Signals Establish Phylogenetic Identity of the Teleost Spine. 
  • Orthopaedic resident education--it's a whole new game: "If I'm going to be a spine surgeon, why do I need to learn how to reconstruct an anterior cruciate ligament?": AOA critical issues. 
  • Outcomes and Complications in Management of Congenital Myopathy Early-Onset Scoliosis. 
  • Outcomes following surgical intervention for impending and gross instability caused by multiple myeloma in the spinal column. 
  • Patient Satisfaction and Press Ganey Scores for Spine Versus Nonspine Neurosurgery Clinics. 
  • Pediatric spinal deformities. 
  • Percentage change in hemoglobin level and morbidity in spine surgery patients. 
  • Perioperative Optimization of Senior Health in Spine Surgery: Impact on Postoperative Delirium. 
  • Peripheral nerve block techniques for ambulatory surgery. 
  • Pilot assessment of a radiologic classification system for segmentation defects of the vertebrae. 
  • Plastic Surgeon Closure of Index Spinal Cases: A Single-Institution Review of 928 Cases. 
  • Posterior global malalignment after osteotomy for sagittal plane deformity: it happens and here is why. 
  • Predicting survival for metastatic spine disease: a comparison of nine scoring systems. 
  • Preemptive analgesia for postoperative pain relief in thoracolumbosacral spine operations: a double-blind, placebo-controlled randomized trial. 
  • Prehospital spinal immobilization and the backboard quality assessment study. 
  • Preoperative optimization for patients undergoing elective spine surgery. 
  • Prevalence and type of cervical deformity among 470 adults with thoracolumbar deformity. 
  • Progress in the understanding of the genetic etiology of vertebral segmentation disorders in humans. 
  • Progressive Spinal Kyphosis in the Aging Population. 
  • Prophylactic use of intraoperative vancomycin powder and postoperative infection: an analysis of microbiological patterns in 1200 consecutive surgical cases. 
  • Prospective Multicenter Assessment of Early Complication Rates Associated With Adult Cervical Deformity Surgery in 78 Patients. 
  • Prospective multicenter assessment of perioperative and minimum 2-year postoperative complication rates associated with adult spinal deformity surgery. 
  • Quality Outcomes Database Spine Care Project 2012-2020: milestones achieved in a collaborative North American outcomes registry to advance value-based spine care and evolution to the American Spine Registry. 
  • Race as a predictor of postoperative hospital readmission after spine surgery. 
  • Radiation injury of the kidney. 
  • Radiation safety and spine surgery: systematic review of exposure limits and methods to minimize radiation exposure. 
  • Radiographical and Implant-Related Complications in Adult Spinal Deformity Surgery: Incidence, Patient Risk Factors, and Impact on Health-Related Quality of Life. 
  • Radiographical spinopelvic parameters and disability in the setting of adult spinal deformity: a prospective multicenter analysis. 
  • Radiology reports for incidental thyroid nodules on CT and MRI: high variability across subspecialties. 
  • Radiotherapy and Surgical Advances in the Treatment of Metastatic Spine Tumors: A Narrative Review. 
  • Rates and causes of mortality associated with spine surgery based on 108,419 procedures: a review of the Scoliosis Research Society Morbidity and Mortality Database. 
  • Recovery kinetics following spinal deformity correction: a comparison of isolated cervical, thoracolumbar, and combined deformity morphometries. 
  • Relationships between mobility of axial structures and physical performance. 
  • Reliability of impairment and physical performance measures for persons with Parkinson's disease. 
  • Reoperation rates and impact on outcome in a large, prospective, multicenter, adult spinal deformity database: clinical article. 
  • Results of the AANS membership survey of adult spinal deformity knowledge: impact of training, practice experience, and assessment of potential areas for improved education: Clinical article. 
  • Revision Surgery Rates After Minimally Invasive Adult Spinal Deformity Surgery: Correlation with Roussouly Spine Type at 2-Year Follow-Up? 
  • Revision extension to the pelvis versus primary spinopelvic instrumentation in adult deformity: comparison of clinical outcomes and complications. 
  • Risk factors for infection after orthopaedic spine surgery at a high-volume institution. 
  • Robotic navigation in spine surgery: Where are we now and where are we going? 
  • Rod Fracture After Apparently Solid Radiographic Fusion in Adult Spinal Deformity Patients. 
  • Rotational thromboelastometry-guided transfusion during lumbar pedicle subtraction osteotomy for adult spinal deformity: preliminary findings from a matched cohort study. 
  • Safety and Diagnostic Efficacy of Gadobenate Dimeglumine in MRI of the Brain and Spine of Neonates and Infants. 
  • Sagittal realignment failures following pedicle subtraction osteotomy surgery: are we doing enough?: Clinical article. 
  • Sagittal spino-pelvic alignment failures following three column thoracic osteotomy for adult spinal deformity. 
  • Sagittal spinopelvic malalignment in Parkinson disease: prevalence and associations with disease severity. 
  • Sagittal spinopelvic parameters in children with achondroplasia: identification of 2 distinct groups. 
  • Salmon calcitonin reduces vertebral bone loss in glucocorticoid-treated beagles. 
  • Seasonal Variation of Common Surgical Site Infections: Does Season Matter? 
  • Sexual Dysfunction Secondary to Lumbar Stiffness in Adult Spinal Deformity Patients Before and After Long-Segment Spinal Fusion. 
  • Smartphone Use and Interest in a Spine Surgery Recovery Mobile Application Among Patients in a US Academic Neurosurgery Practice. 
  • Spinal Arterial Blood Supply Does Not Arise from the Bronchial Arteries: A Detailed Analysis of Angiographic Studies Performed for Hemoptysis. 
  • Spinal deformity surgery. 
  • Spinal flexibility and balance control among community-dwelling adults with and without Parkinson's disease. 
  • Spinal instability neoplastic score: an analysis of reliability and validity from the spine oncology study group. 
  • Spinal movement and performance of a standing reach task in participants with and without Parkinson disease. 
  • Spinal surgery: variations in health care costs and implications for episode-based bundled payments. 
  • Spinal-flexibility-plus-aerobic versus aerobic-only training: effect of a randomized clinical trial on function in at-risk older adults. 
  • Spine Patterning Is Guided by Segmentation of the Notochord Sheath. 
  • Staying ahead of the curve: the use of spinopelvic parameters to predict curve progression and bracing success in adolescent idiopathic scoliosis. 
  • Stratifying outcome based on the Oswestry Disability Index for operative treatment of adult spinal deformity on patients 60 years of age or older: a multicenter, multi-continental study on Prospective Evaluation of Elderly Deformity Surgery (PEEDS). 
  • Surface coil imaging of rat spine at 7.0 T. 
  • Syrinx location and size according to etiology: identification of Chiari-associated syrinx. 
  • TNF is required for the induction but not the maintenance of compression-induced BME signals in murine tail vertebrae: limitations of anti-TNF therapy for degenerative disc disease. 
  • Terminology. 
  • The BMP antagonist Noggin promotes cranial and spinal neurulation by distinct mechanisms. 
  • The Canadian experience with long-term deflazacort treatment in Duchenne muscular dystrophy. 
  • The Impact of Instrumentation and Implant Surface Technology on Cervical and Thoracolumbar Fusion. 
  • The SRS-Schwab adult spinal deformity classification: assessment and clinical correlations based on a prospective operative and nonoperative cohort. 
  • The biomechanics of pedicle screw augmentation with cement. 
  • The comprehensive anatomical spinal osteotomy classification. 
  • The epidemiology of spinal tuberculosis in the United States: an analysis of 2002-2011 data. 
  • The hematological effects of nitrous oxide anesthesia in pediatric patients. 
  • The implementation and efficacy of the Northwestern High Risk Spine Protocol. 
  • The injured canine cervical spine after six months of healing. An in vitro three-dimensional study. 
  • The medicolegal impact of misplaced pedicle and lateral mass screws on spine surgery in the United States. 
  • The minimally invasive spinal deformity surgery algorithm: a reproducible rational framework for decision making in minimally invasive spinal deformity surgery. 
  • The role of imaging and in situ biomechanical testing in assessing pedicle screw pull-out strength. 
  • The spino-pelvic ratio: a novel global sagittal parameter associated with clinical outcomes in adult spinal deformity patients. 
  • The use of G-CSF during craniospinal irradiation. 
  • The use of an expandable cage for corpectomy reconstruction of vertebral body tumors through a posterior extracavitary approach: a multicenter consecutive case series of prospectively followed patients. 
  • The use of animal-assisted therapy in combination with physical therapy in an inpatient rehabilitation facility: A case report. 
  • The vertebrae and ribs of Homo naledi. 
  • The vertebral column of Australopithecus sediba. 
  • The winged helix transcription factor MFH1 is required for proliferation and patterning of paraxial mesoderm in the mouse embryo. 
  • Thoracic spine thrust manipulation for individuals with cervicogenic headache: a crossover randomized clinical trial. 
  • Three-dimensional analysis of cervical spine motion: reliability of a computer assisted magnetic tracking device compared to inclinometer. 
  • Thrombospondin receptor α2δ-1 promotes synaptogenesis and spinogenesis via postsynaptic Rac1. 
  • Timing of surgery and radiotherapy in the management of metastatic spine disease: a systematic review. 
  • Unilateral versus bilateral lower extremity motor deficit following complex adult spinal deformity surgery: is there a difference in recovery up to 2-year follow-up? 
  • Unusual presentation and complication of the prone position for spinal surgery. 
  • Use of endo-vaginal ultrasound to optimize visualization of the distal fetal spine in breech presentations. 
  • VATER and hydrocephalus: distinct syndrome? 
  • Venous thromboembolism in spine surgery. 
  • Ventilator Mode Does Not Influence Blood Loss or Transfusion Requirements During Major Spine Surgery: A Retrospective Study. 
  • Virtual Spine: A Novel, International Teleconferencing Program Developed to Increase the Accessibility of Spine Education During the COVID-19 Pandemic. 
  • Visual loss after spine surgery: a population-based study. 
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  Keywords of People

  • Clewley, Derek James, Assistant Professor in Orthopaedic Surgery, Orthopaedics, Physical Therapy
  • Than, Khoi Duc, Associate Professor of Neurosurgery, Neurosurgery