Splenectomy

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  Subject Areas on Research

  • A molecular defect in two families with hemolytic poikilocytic anemia: reduction of high affinity membrane binding sites for ankyrin. 
  • A monoclonal IgM with antibodylike specificity for phospholipids in a patient with lymphoma. 
  • A randomized comparison of two doses of human lymphoblastoid interferon-alpha in hairy cell leukemia. Wellcome HCL Study Group. 
  • A retrospective analysis of the long-term effect of splenectomy on late infections, graft-versus-host disease, relapse, and survival after allogeneic marrow transplantation for chronic myelogenous leukemia. 
  • A synergistic effect of total lymphoid irradiation, cyclosporine, and splenectomy in a hamster-to-rat hepatic xenograft model. 
  • Allogeneic marrow transplantation in patients with chronic myeloid leukemia in the chronic phase: a randomized trial of two irradiation regimens. 
  • Angiotensin II mobilizes spleen monocytes to promote the development of abdominal aortic aneurysm in Apoe-/- mice. 
  • Atraumatic splenic rupture from Babesia: A disease of the otherwise healthy patient. 
  • Brucellosis. Indications for splenectomy. 
  • Capnocytophagia canimorsus sepsis in an asplenic heart transplant candidate with a left ventricular assist system. 
  • Clinical and hematologic benefits of partial splenectomy for congenital hemolytic anemias in children. 
  • Clinical management of adult ITP prior to splenectomy: a perspective. 
  • Clinical outcomes of splenectomy in children: report of the splenectomy in congenital hemolytic anemia registry. 
  • Clinical spectrum of pyruvate kinase deficiency: data from the Pyruvate Kinase Deficiency Natural History Study. 
  • Coil embolization of the splenic artery: impact on splenic volume. 
  • Comparative effectiveness of different types of splenectomy for children with congenital hemolytic anemias. 
  • Comparative effectiveness of treatment strategies for severe splenic trauma in the pediatric population. 
  • Conversion factors for laparoscopic splenectomy for immune thrombocytopenic purpura. 
  • Corticosteroid-induced lymphocytopenia in man: absence of splenic influence and effect of recipient serum. 
  • Cytokine-induced mobilization of circulating endothelial progenitor cells enhances repair of injured arteries. 
  • Cytokinetically based induction chemotherapy and splenectomy for childhood acute nonlymphocytic leukemia. 
  • Delayed presentation of splenic injury: still a common syndrome. 
  • Echinocytosis--an unusual manifestation of hemangioma. 
  • Effects of corticosteroids and splenectomy on the immune clearance and destruction of erythrocytes. 
  • Effects of immunosuppression and pretransplant splenectomy in newborn cardiac xenograft survival. 
  • Effects of nitrogen mustard and splenectomy on mouse bone marrow colony formation in vitro. 
  • Effects of pretransplant splenectomy and immunosuppression of humoral immunity in a pig-to-newborn goat cardiac xenograft model. 
  • Effects of terlipressin versus splenectomy on liver regeneration after partial hepatectomy in rats: What we know so far? 
  • Evaluation of partial and total splenectomy in children with sickle cell disease using an Internet-based registry. 
  • Experimental Babesia bovis infection in Holstein calves. 
  • Failure of splenectomy in Felty's syndrome. The role of antibodies supporting granulocyte lysis by lymphocytes. 
  • HIV-1-associated thrombocytopenia. The role of splenectomy. 
  • Hairy cell leukemia: an elusive but treatable disease. 
  • Hematologic outcomes after total splenectomy and partial splenectomy for congenital hemolytic anemia. 
  • Hereditary spherocytosis and partial splenectomy in children: review of surgical technique and the role of imaging. 
  • Idiopathic autoimmune thrombocytopenic purpura. 
  • Immunologic studies before and after splenectomy in a patient with the Wiskott-Aldrich syndrome. 
  • Immunologic studies on T and B lymphocytes in chimpanzees: effects of thymectomy and irradiation. 
  • Impaired immune response of splenectomised patients to polyvalent pneumococcal vaccine. 
  • Inflammatory pseudotumor of the spleen: a case report. 
  • Influence of nitroglycerin on splanchnic capacity and splanchnic capacity-cardiac output relationship. 
  • Influence of splanchnic intravascular volume changes on cardiac output during muscarinic receptor stimulation in the anaesthetized dog. 
  • Laparoscopic Splenectomy for Benign Hematological Disorders in Adults: A Systematic Review. 
  • Laparoscopic distal pancreatectomy with splenic preservation. 
  • Laparoscopy is safe among patients with congestive heart failure undergoing general surgery procedures. 
  • Late Infection-Related Mortality in Asplenic Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study. 
  • Leiomyosarcoma of the splenic vein. 
  • Long-term management of splenic sequestration in children with sickle cell disease. 
  • Macrophage migration into hepatic xenografts in the hamster-to-rat combination. 
  • Marrow transplantation for patients in accelerated phase of chronic myeloid leukemia. 
  • Modalities of preservation of the traumatized spleen. 
  • NIH Conference: Immunoglobulin G Fc receptor-mediated clearance in autoimmune diseases. 
  • NIH conference. Pathophysiology of immune hemolytic anemia. 
  • Nonoperative Management Is as Effective as Immediate Splenectomy for Adult Patients with High-Grade Blunt Splenic Injury. 
  • Opsonic requirements for intravascular clearance after splenectomy. 
  • Outcomes following splenectomy in patients with myeloid neoplasms. 
  • Partial splenectomy before a hematopoietic stem cell transplantation in children. 
  • Partial splenectomy but not total splenectomy preserves immunoglobulin M memory B cells in mice. 
  • Partial splenectomy for children with congenital hemolytic anemia and massive splenomegaly. 
  • Partial splenectomy for hereditary spherocytosis. 
  • Partial splenectomy for hereditary spherocytosis: a multi-institutional review. 
  • Partial splenectomy for symptomatic splenic hamartoma. 
  • Persistent thrombocytopaenia in a young man with splenomegaly, rebound thrombocytosis after splenectomy and subsequent pulmonary embolism: splenic littoral cell angioma and associated events. 
  • Physician decision making in selection of second-line treatments in immune thrombocytopenia in children. 
  • Platelet antibody in prolonged remission of childhood idiopathic thrombocytopenic purpura. 
  • Pneumococcal vaccine administration associated with splenectomy: the need for improved education, documentation, and the use of a practical checklist. 
  • Prognostic implications for direct platelet-associated IgG in childhood idiopathic thrombocytopenic purpura. 
  • Prolonged survival of hepatic xenografts in the hamster to rat combination: efficacy of cyclosporine in combination with splenectomy. 
  • Rate of bleeding-related episodes in elderly patients with primary immune thrombocytopenia: a retrospective cohort study. 
  • Relapse of thrombotic thrombocytopenic purpura: is it a continuum of disease? 
  • Retransplantation in the diabetic with a pancreas allograft after previous kidney or pancreas transplant. 
  • Risk factors for renal allograft loss in patients with systemic lupus erythematosus. 
  • Short-term outcomes of splenectomy avoidance in trauma patients. 
  • Significant prolongation of hamster liver transplant survival in Lewis rats by total-lymphoid irradiation, cyclosporine, and splenectomy. 
  • Sonographic appearance of oxidized cellulose (Surgicel): pitfall in the diagnosis of postoperative abscess. 
  • Splenectomy and partial splenectomy improve hematopoietic stem cell engraftment in hypersplenic mice. 
  • Splenectomy as a Destination: Improving Quality of Care Among Asplenic Veterans Through a Travel Clinic. 
  • Splenectomy for Felty's syndrome. Clinicopathological study of 27 patients. 
  • Splenectomy for primary and recurrent immune thrombocytopenic purpura (ITP). Current criteria for patient selection and results. 
  • Splenectomy in sickle-cell disease. 
  • Splenectomy is not indicated in living donor liver transplantation. 
  • Splenic Irradiation for the Treatment of Severe Antibody-Mediated Rejection. 
  • Subtotal splenic embolization is a safe and effective treatment for isolated splenic vascular tumors associated with consumptive coagulopathy. 
  • Surgical and obstetric outcomes in adults with sickle cell disease. 
  • The role of complement in the in vivo destruction of erythrocytes. 
  • The role of the spleen in experimental pneumococcal bacteremia. 
  • The significance of splenomegaly in 101 adults with acute lymphoblastic leukemia (ALL) at presentation and during remission. 
  • Therapeutic considerations in childhood idiopathic thrombocytopenic purpura. 
  • Thrombotic thrombocytopenic purpura occurring despite absence of the spleen: report of case. 
  • Transformation in pretreatment manifestations of Gaucher disease type 1 during two decades of alglucerase/imiglucerase enzyme replacement therapy in the International Collaborative Gaucher Group (ICGG) Gaucher Registry. 
  • Treatment of multiple aneurysms of the splenic artery after liver transplantation by percutaneous embolization and laparoscopic splenectomy. 
  • Understanding splenectomy for children with hereditary spherocytosis. 
  • Upper gastrointestinal bleeding from gastric submucosal arterial collaterals secondary to splenic artery occlusion: treatment by splenectomy and partial gastric devascularization. 
  • Velaglucerase alfa enzyme replacement therapy compared with imiglucerase in patients with Gaucher disease. 
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  Keywords of People

  • Bennett, Vann, George B. Geller Distinguished Professor for Research in Molecular Biology in the School of Medicine, Duke Cancer Institute
  • Kim, Charles Yoon, Associate Professor of Radiology, Radiology, Interventional Radiology
  • Roy Choudhury, Kingshuk, Adjunct Associate Professor in the Department of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics