Staphylococcus aureus

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  Subject Areas on Research

  • A Prognostic Model of Persistent Bacteremia and Mortality in Complicated Staphylococcus aureus Bloodstream Infection. 
  • A Test for the Rapid Detection of the Cefazolin Inoculum Effect in Methicillin-Susceptible Staphylococcus aureus. 
  • A randomized Phase 2 trial of telavancin versus standard therapy in patients with uncomplicated Staphylococcus aureus bacteremia: the ASSURE study. 
  • A tactile response in Staphylococcus aureus. 
  • A thioesterase bypasses the requirement for exogenous fatty acids in the plsX deletion of Streptococcus pneumoniae. 
  • A time-kill evaluation of clarithromycin and azithromycin against two extracellular pathogens and the development of resistance. 
  • A toll-like receptor 2 pathway regulates the Ppargc1a/b metabolic co-activators in mice with Staphylococcal aureus sepsis. 
  • Accelerated induction of experimental allergic encephalomyelitis in PL/J mice by a non-V beta 8-specific superantigen. 
  • Activation of mitochondrial biogenesis by heme oxygenase-1-mediated NF-E2-related factor-2 induction rescues mice from lethal Staphylococcus aureus sepsis. 
  • Acute osteomyelitis of the pubic symphysis following cardiac catheterization. 
  • Adverse clinical and economic outcomes attributable to methicillin resistance among patients with Staphylococcus aureus surgical site infection. 
  • Altered Mitochondrial Homeostasis during Systemic Lupus Erythematosus Impairs Neutrophil Extracellular Trap Formation Rendering Neutrophils Ineffective at Combating Staphylococcus aureus. 
  • Amino acid alterations in fibronectin binding protein A (FnBPA) and bacterial genotype are associated with cardiac device related infection in Staphylococcus aureus bacteraemia. 
  • An economical and preparative orthogonal solid phase synthesis of fluorescein and rhodamine derivatized peptides: FRET substrates for the Staphylococcus aureus sortase SrtA transpeptidase reaction. 
  • Anaerobic resistance of clinical isolates of Staphylococcus aureus to aminoglycosides. 
  • Analysis of the impact of early surgery on in-hospital mortality of native valve endocarditis: use of propensity score and instrumental variable methods to adjust for treatment-selection bias. 
  • Analysis of the substrate specificity of the Staphylococcus aureus sortase transpeptidase SrtA. 
  • Analysis of two- and three-year trends in antimicrobial resistance in intensive care units using unit-specific antibiograms. 
  • Antimicrobial activity of a continuously active disinfectant against healthcare pathogens. 
  • Antiplatelet Therapy in Staphylococcus aureus Bacteremia: No Time Like the Past? 
  • Apple pectin-derived oligosaccharides produce carbon dioxide radical anion in Fenton reaction and prevent growth of Escherichia coli and Staphylococcus aureus. 
  • Association between the timing of surgery for complicated, left-sided infective endocarditis and survival. 
  • Association of an Active Surveillance and Decolonization Program on Incidence of Clinical Cultures Growing Staphylococcus aureus in the Neonatal Intensive Care Unit. 
  • Associations between the genotypes of Staphylococcus aureus bloodstream isolates and clinical characteristics and outcomes of bacteremic patients. 
  • Autosomal Dominant Hyper-IgE Syndrome in the USIDNET Registry. 
  • Bacteremia, Sepsis, and Infective Endocarditis Associated with Staphylococcus aureus. 
  • Bacteremia, central catheters, and neonates: when to pull the line. 
  • Bacterial genotype and clinical outcomes in solid organ transplant recipients with Staphylococcus aureus bacteremia. 
  • Bacterial infection of osteoblasts induces interleukin-1beta and interleukin-18 transcription but not protein synthesis. 
  • Bacteriophage K antimicrobial-lock technique for treatment of Staphylococcus aureus central venous catheter-related infection: a leporine model efficacy analysis. 
  • Bioburden after Staphylococcus aureus inoculation in type 1 diabetic rats undergoing internal fixation. 
  • Bioreduction of nitroxides by Staphylococcus aureus. 
  • Bloodstream infections in community hospitals in the 21st century: a multicenter cohort study. 
  • Bonds between fibronectin and fibronectin-binding proteins on Staphylococcus aureus and Lactococcus lactis. 
  • Bovine TLR2 and TLR4 properly transduce signals from Staphylococcus aureus and E. coli, but S. aureus fails to both activate NF-kappaB in mammary epithelial cells and to quickly induce TNFalpha and interleukin-8 (CXCL8) expression in the udder. 
  • Burden of Invasive Staphylococcus aureus Infections in Hospitalized Infants. 
  • Candidate genes on murine chromosome 8 are associated with susceptibility to Staphylococcus aureus infection in mice and are involved with Staphylococcus aureus septicemia in humans. 
  • Ceftobiprole versus daptomycin in Staphylococcus aureus bacteremia: a novel protocol for a double-blind, Phase III trial. 
  • Changing Characteristics of Staphylococcus aureus Bacteremia: Results From a 21-Year, Prospective, Longitudinal Study. 
  • Changing patient characteristics and the effect on mortality in endocarditis. 
  • Characterization of Staphylococcus aureus Cas9: a smaller Cas9 for all-in-one adeno-associated virus delivery and paired nickase applications. 
  • Characterization of alpha-toxin hla gene variants, alpha-toxin expression levels, and levels of antibody to alpha-toxin in hemodialysis and postsurgical patients with Staphylococcus aureus bacteremia. 
  • Characterization of the SarA virulence gene regulator of Staphylococcus aureus. 
  • Chelating agents exert distinct effects on biofilm formation in Staphylococcus aureus depending on strain background: role for clumping factor B. 
  • Chiral evasion and stereospecific antifolate resistance in Staphylococcus aureus. 
  • Clindamycin Pharmacokinetics and Safety in Preterm and Term Infants. 
  • Clinical characteristics and outcomes of diabetic patients with Staphylococcus aureus bacteremia and endocarditis. 
  • Clinical consensus conference: survey on Gram-positive bloodstream infections with a focus on Staphylococcus aureus. 
  • Clinical management of Staphylococcus aureus bacteremia: a review. 
  • Clinical outcomes and costs among patients with Staphylococcus aureus bacteremia and orthopedic device infections. 
  • Clinical outcomes and costs due to Staphylococcus aureus bacteremia among patients receiving long-term hemodialysis. 
  • Clinical presentation, etiology, and outcome of infective endocarditis in the 21st century: the International Collaboration on Endocarditis-Prospective Cohort Study. 
  • Coagulase-negative staphylococcal prosthetic valve endocarditis--a contemporary update based on the International Collaboration on Endocarditis: prospective cohort study. 
  • Colonization, pathogenicity, host susceptibility, and therapeutics for Staphylococcus aureus: what is the clinical relevance? 
  • Community-associated methicillin-resistant Staphylococcus aureus necrotizing fasciitis in a neonate. 
  • Comparative evaluation of supplemented peptone broth with sodium polyanetholesulfonate and trypticase soy broth with sodium amylosulfate for detection of septicemia. 
  • Comparative evaluation of the microbicidal activity of low-temperature sterilization technologies to steam sterilization. 
  • Comparative study of α-helical and β-sheet self-assembled peptide nanofiber vaccine platforms: influence of integrated T-cell epitopes. 
  • Complement levels in patients with bloodstream infection due to Staphylococcus aureus or Gram-negative bacteria. 
  • Comèl-Netherton syndrome defined as primary immunodeficiency. 
  • Considerations for Clinical Trials of Staphylococcus aureus Bloodstream Infection in Adults. 
  • Contrasting methicillin-resistant Staphylococcus aureus colonization in Veterans Affairs and community nursing homes. 
  • Contribution of urinary tract infection to the burden of febrile illnesses in young children in rural Kenya. 
  • Controlled Release of Vancomycin and Tigecycline from an Orthopaedic Implant Coating Prevents Staphylococcus aureus Infection in an Open Fracture Animal Model. 
  • Controlled clinical comparison of bioMérieux VITAL and BACTEC NR-660 blood culture systems for detection of bacteremia and fungemia in adults. 
  • Controlled evaluation of 5 versus 10 milliliters of blood cultured in aerobic BacT/Alert blood culture bottles. 
  • Controlled multicenter evaluation of a bacteriophage-based method for rapid detection of Staphylococcus aureus in positive blood cultures. 
  • Correlation between fundamental binding forces and clinical prognosis of Staphylococcus aureus infections of medical implants. 
  • Costs and outcomes among hemodialysis-dependent patients with methicillin-resistant or methicillin-susceptible Staphylococcus aureus bacteremia. 
  • Critical role of NOD2 in regulating the immune response to Staphylococcus aureus. 
  • Crystal structures of SarA, a pleiotropic regulator of virulence genes in S. aureus. 
  • DNA-remethylation around a STAT5-binding enhancer in the alphaS1-casein promoter is associated with abrupt shutdown of alphaS1-casein synthesis during acute mastitis. 
  • Dalbavancin as an option for treatment of S. aureus bacteremia (DOTS): study protocol for a phase 2b, multicenter, randomized, open-label clinical trial. 
  • Daptomycin use in infants: report of two cases with peak and trough drug concentrations. 
  • Daptomycin versus standard therapy for bacteremia and endocarditis caused by Staphylococcus aureus. 
  • Deciphering the molecular basis of multidrug recognition: crystal structures of the Staphylococcus aureus multidrug binding transcription regulator QacR. 
  • Defining persistent Staphylococcus aureus bacteraemia: secondary analysis of a prospective cohort study. 
  • Determination of an inoculum effect with various cephalosporins among clinical isolates of methicillin-susceptible Staphylococcus aureus. 
  • Development of a high-performance liquid chromatography assay and revision of kinetic parameters for the Staphylococcus aureus sortase transpeptidase SrtA. 
  • Development of a vaccine against Staphylococcus aureus invasive infections: Evidence based on human immunity, genetics and bacterial evasion mechanisms. 
  • Development of pooled suppression subtractive hybridization to analyze the pangenome of Staphylococcus aureus. 
  • Differential regulation of the PGC family of genes in a mouse model of Staphylococcus aureus sepsis. 
  • Direct-from-blood RNA sequencing identifies the cause of post-bronchoscopy fever. 
  • Disinfectant testing using a modified use-dilution method: collaborative study. 
  • Dissemination of an Enterococcus Inc18-Like vanA plasmid associated with vancomycin-resistant Staphylococcus aureus. 
  • Dissociation rate constants of human fibronectin binding to fibronectin-binding proteins on living Staphylococcus aureus isolated from clinical patients. 
  • Duration of antibiotic therapy for Staphylococcus aureus bacteraemia: the long and the short of it. 
  • Early Oral Antibiotic Switch for Staphylococcus aureus Bacteremia: Many Are Called, but Few Are Chosen. 
  • Echocardiographic documentation of vegetative lesions in infective endocarditis: clinical implications. 
  • Effect of Algorithm-Based Therapy vs Usual Care on Clinical Success and Serious Adverse Events in Patients with Staphylococcal Bacteremia: A Randomized Clinical Trial. 
  • Effect of an investigational vaccine for preventing Staphylococcus aureus infections after cardiothoracic surgery: a randomized trial. 
  • Effect of human serum on inhibition of growth of Staphylococcus aureus by antimicrobial agents. 
  • Effect of vancomycin serum trough levels on outcomes in patients with nosocomial pneumonia due to Staphylococcus aureus: a retrospective, post hoc, subgroup analysis of the Phase 3 ATTAIN studies. 
  • Emergence of nosocomial methicillin-resistant Staphylococcus aureus and therapy of colonized personnel during a hospital-wide outbreak. 
  • Emerging options for treatment of invasive, multidrug-resistant Staphylococcus aureus infections. 
  • Endocarditis caused by Staphylococcus aureus with reduced susceptibility to vancomycin. 
  • Endocarditis from Staphylococcus aureus. 
  • Engineering the substrate specificity of Staphylococcus aureus Sortase A. The beta6/beta7 loop from SrtB confers NPQTN recognition to SrtA. 
  • Epidemiology and risk factors for recurrent Staphylococcus aureus colonization following active surveillance and decolonization in the NICU. 
  • Epidemiology of Staphylococcus aureus infections in patients admitted to freestanding pediatric hospitals, 2009-2016. 
  • Epidemiology of methicillin-resistant Staphylococcus aureus. 
  • Escherichia coli, but not Staphylococcus aureus triggers an early increased expression of factors contributing to the innate immune defense in the udder of the cow. 
  • Evaluating genetic susceptibility to Staphylococcus aureus bacteremia in African Americans using admixture mapping. 
  • Evaluation of an antimicrobial-impregnated continuous ambulatory peritoneal dialysis catheter for infection control in rats. 
  • FabH mutations confer resistance to FabF-directed antibiotics in Staphylococcus aureus. 
  • Fatal outcome of bacteraemic patients caused by infection with staphylokinase-deficient Staphylococcus aureus strains. 
  • Fibrinogen binding is affected by amino acid substitutions in C-terminal repeat region of fibronectin binding protein A. 
  • Frequency of infective endocarditis among infants and children with Staphylococcus aureus bacteremia. 
  • Functional consequences of substitution mutations in MepR, a repressor of the Staphylococcus aureus MepA multidrug efflux pump gene. 
  • Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli. 
  • Functional heterogeneity of type 1 fimbriae of Escherichia coli. 
  • Functional polymer brushes via surface-initiated atom transfer radical graft polymerization for combating marine biofouling. 
  • Gene expression-based classifiers identify Staphylococcus aureus infection in mice and humans. 
  • Generation of ramoplanin-resistant Staphylococcus aureus. 
  • Genetic variability in beta-defensins is not associated with susceptibility to Staphylococcus aureus bacteremia. 
  • Genotypic characteristics of Staphylococcus aureus isolates from a multinational trial of complicated skin and skin structure infections. 
  • Good Studies Evaluate the Disease While Great Studies Evaluate the Patient: Development and Application of a Desirability of Outcome Ranking Endpoint for Staphylococcus aureus Bloodstream Infection. 
  • High-density microarray of small-subunit ribosomal DNA probes. 
  • High-dose daptomycin therapy for left-sided infective endocarditis: a prospective study from the international collaboration on endocarditis. 
  • Histone acetylation in keratinocytes enables control of the expression of cathelicidin and CD14 by 1,25-dihydroxyvitamin D3. 
  • Human IFN-gamma production is inhibited by a synthetic peptide homologous to retroviral envelope protein. 
  • Human genetic variation in GLS2 is associated with development of complicated Staphylococcus aureus bacteremia. 
  • Identification of a two-component fatty acid kinase responsible for host fatty acid incorporation by Staphylococcus aureus. 
  • Immune dysregulation and osteosarcoma: Staphylococcus aureus downregulates TGF-β and heightens the inflammatory signature in human and canine macrophages suppressed by osteosarcoma. 
  • Immunostimulatory properties of genomic DNA from different bacterial species. 
  • Impact of Bacterial and Human Genetic Variation on Staphylococcus aureus Infections. 
  • Impact of Immunosuppressive Agents on Clinical Manifestations and Outcome of Staphylococcus aureus Bloodstream Infection: A Propensity Score-Matched Analysis in 2 Large, Prospectively Evaluated Cohorts. 
  • Impact of early valve surgery on outcome of Staphylococcus aureus prosthetic valve infective endocarditis: analysis in the International Collaboration of Endocarditis-Prospective Cohort Study. 
  • Importance of aggressive evaluation in patients with Staphylococcus aureus bacteremia. 
  • In Vivo Efficacy of a ´93Smart´94 Antimicrobial Implant Coating 
  • In vitro resistance to thrombin-induced platelet microbicidal protein among clinical bacteremic isolates of Staphylococcus aureus correlates with an endovascular infectious source. 
  • In vitro resistance to thrombin-induced platelet microbicidal protein in isolates of Staphylococcus aureus from endocarditis patients correlates with an intravascular device source. 
  • In-vitro modelling of the bactericidal activity of teicoplanin versus flucloxacillin as used in surgical prophylaxis, against Staphylococcus aureus. 
  • Incorporation of extracellular fatty acids by a fatty acid kinase-dependent pathway in Staphylococcus aureus. 
  • Increased in vitro phenol-soluble modulin production is associated with soft tissue infection source in clinical isolates of methicillin-susceptible Staphylococcus aureus. 
  • Increased risk of Staphylococcus aureus bacteremia in hemodialysis-A nationwide study. 
  • Increasing Clindamycin and Trimethoprim-Sulfamethoxazole Resistance in Pediatric Staphylococcus aureus Infections. 
  • Increasing US rates of endocarditis with Staphylococcus aureus: 1999-2008. 
  • Infection of orthopedic prostheses after Staphylococcus aureus bacteremia. 
  • Infective endocarditis due to Staphylococcus aureus: 59 prospectively identified cases with follow-up. 
  • Influence of diabetes mellitus on the clinical manifestations and prognosis of infective endocarditis: a report from the International Collaboration on Endocarditis-Merged Database. 
  • Influence of host genetics and environment on nasal carriage of staphylococcus aureus in danish middle-aged and elderly twins. 
  • Influence of vancomycin minimum inhibitory concentration on the outcome of methicillin-susceptible Staphylococcus aureus left-sided infective endocarditis treated with antistaphylococcal β-lactam antibiotics: a prospective cohort study by the International Collaboration on Endocarditis. 
  • Inhibition of the Staphylococcus aureus sortase transpeptidase SrtA by phosphinic peptidomimetics. 
  • Initial low-dose gentamicin for Staphylococcus aureus bacteremia and endocarditis is nephrotoxic. 
  • Inoculum effect with cefazolin among clinical isolates of methicillin-susceptible Staphylococcus aureus: frequency and possible cause of cefazolin treatment failure. 
  • Integrin beta 1 regulates phagosome maturation in macrophages through Rac expression. 
  • Interaction of cefotaxime and desacetylcefotaxime against pathogenic bacteria. Assessment with the serum bactericidal test. 
  • Interpretive criteria and quality control for antimicrobial susceptibility tests of levofloxacin. 
  • Intestinal Microbiota of Mice Influences Resistance to Staphylococcus aureus Pneumonia. 
  • Isolation, structure and biological activities of platensimycin B4 from Streptomyces platensis. 
  • Isotretinoin and Staphylococcus aureus infection. A possible association. 
  • Lack of efficacy for conventional gamma irradiation of platelet concentrates to abrogate bacterial growth. 
  • Lacrimal gland abscess in a child as a rare manifestation of IgG4-related disease. 
  • Low-Avidity Autoantibodies against Bactericidal/Permeability-Increasing Protein Occur in Gram-Negative and Gram-Positive Bacteremia. 
  • MRGPR-mediated activation of local mast cells clears cutaneous bacterial infection and protects against reinfection. 
  • MRSA nares swab is a more accurate predictor of MRSA wound infection compared with clinical risk factors in emergency department patients with skin and soft tissue infections. 
  • Macrophage-Produced Peroxynitrite Induces Antibiotic Tolerance and Supersedes Intrinsic Mechanisms of Persister Formation. 
  • Management Considerations in Infective Endocarditis: A Review. 
  • Management of methicillin-resistant Staphylococcus aureus bacteremia. 
  • Management of skin abscesses by primary care pediatricians. 
  • Mapping Hfq-RNA interaction surfaces using tryptophan fluorescence quenching. 
  • Mechanism of Reduction of an Aminyl Radical Intermediate in the Radical SAM GTP 3',8-Cyclase MoaA. 
  • Mechanism of staphylococcal multiresistance plasmid replication origin assembly by the RepA protein. 
  • Mechanistic Investigation of cPMP Synthase in Molybdenum Cofactor Biosynthesis Using an Uncleavable Substrate Analogue. 
  • Membrane disruption by antimicrobial fatty acids releases low-molecular-weight proteins from Staphylococcus aureus. 
  • Metabolic basis for the differential susceptibility of Gram-positive pathogens to fatty acid synthesis inhibitors. 
  • Methicillin-resistant Staphylococcus aureus bacteremia after isolation from urine. 
  • Methicillin-resistant Staphylococcus aureus in hospitals: time for a culture change. 
  • Methicillin-resistant Staphylococcus aureus outbreak in an intensive care nursery: potential for interinstitutional spread. 
  • Methicillin-susceptible Staphylococcus aureus endocarditis isolates are associated with clonal complex 30 genotype and a distinct repertoire of enterotoxins and adhesins. 
  • Mice lacking neutrophil elastase reveal impaired host defense against gram negative bacterial sepsis. 
  • Microbial Cell-Free DNA Identifies Etiology of Bloodstream Infections, Persists Longer Than Conventional Blood Cultures, and Its Duration of Detection Is Associated With Metastatic Infection in Patients With Staphylococcus aureus and Gram-Negative Bacteremia. 
  • Microbiological and genotypic analysis of methicillin-resistant Staphylococcus aureus bacteremia. 
  • Minimum inhibitory and bactericidal concentrations of 44 antimicrobial agents against three standard control strains in broth with and without human serum. 
  • Mitochondrial biogenesis restores oxidative metabolism during Staphylococcus aureus sepsis. 
  • Mitochondrial quality control in alveolar epithelial cells damaged by S. aureus pneumonia in mice. 
  • Molecular epidemiology of Staphylococcus aureus mastitis in dairy heifers. 
  • Mortality and neurodevelopmental outcome after Staphylococcus aureus bacteremia in infants. 
  • Multicenter study to determine disk diffusion and broth microdilution criteria for prediction of high- and low-level mupirocin resistance in Staphylococcus aureus. 
  • Multiscale conformational heterogeneity in staphylococcal protein a: possible determinant of functional plasticity. 
  • Mutagenesis studies of substrate recognition and catalysis in the sortase A transpeptidase from Staphylococcus aureus. 
  • Mutational analysis of active site residues in the Staphylococcus aureus transpeptidase SrtA. 
  • Mutations within the mepA operator affect binding of the MepR regulatory protein and its induction by MepA substrates in Staphylococcus aureus. 
  • Myeloid-Specific Deletion of Mcl-1 Yields Severely Neutropenic Mice That Survive and Breed in Homozygous Form. 
  • Nosocomial methicillin-resistant and methicillin-susceptible Staphylococcus aureus primary bacteremia: at what costs? 
  • Nrf2 promotes alveolar mitochondrial biogenesis and resolution of lung injury in Staphylococcus aureus pneumonia in mice. 
  • Ofloxacin, a new broad-spectrum fluoroquinolone. Results from a Multicenter, National Comparative Activity Surveillance Study. The Ofloxacin Surveillance Group. 
  • Optimization of a multiplex CRISPR/Cas system for use as an antiviral therapeutic. 
  • Optimizing therapy for methicillin-resistant Staphylococcus aureus bacteremia. 
  • Osteoblasts express the inflammatory cytokine interleukin-6 in a murine model of Staphylococcus aureus osteomyelitis and infected human bone tissue. 
  • Osteoblasts produce monocyte chemoattractant protein-1 in a murine model of Staphylococcus aureus osteomyelitis and infected human bone tissue. 
  • Outcome of Staphylococcus aureus bacteremia according to compliance with recommendations of infectious diseases specialists: experience with 244 patients. 
  • Outcomes of Staphylococcus aureus infection in hemodialysis-dependent patients. 
  • Outcomes with daptomycin versus standard therapy for osteoarticular infections associated with Staphylococcus aureus bacteraemia. 
  • Panton-Valentine leukocidin is not the primary determinant of outcome for Staphylococcus aureus skin infections: evaluation from the CANVAS studies. 
  • Pathogen flow: what we need to know. 
  • Patients' Experiences With Staphylococcus aureus and Gram-negative Bacterial Bloodstream Infections: A Qualitative Descriptive Study and Concept Elicitation Phase To Inform Measurement of Patient-reported Quality of Life. 
  • Peptide-PEG amphiphiles as cytophobic coatings for mammalian and bacterial cells. 
  • Performance of the cobas MRSA/SA Test for Simultaneous Detection of Methicillin-Susceptible and Methicillin-Resistant Staphylococcus aureus From Nasal Swabs. 
  • Peroxisome proliferator-activated receptor γ co-activator 1-α as a critical co-activator of the murine hepatic oxidative stress response and mitochondrial biogenesis in Staphylococcus aureus sepsis. 
  • Persistence of zinc-binding bacterial superantigens at the surface of antigen-presenting cells contributes to the extreme potency of these superantigens as T-cell activators. 
  • Persistent bacteremia due to methicillin-resistant Staphylococcus aureus infection is associated with agr dysfunction and low-level in vitro resistance to thrombin-induced platelet microbicidal protein. 
  • Perturbation of Staphylococcus aureus gene expression by the enoyl-acyl carrier protein reductase inhibitor AFN-1252. 
  • Phase 2, randomized, double-blind, dose-ranging study evaluating the safety, tolerability, population pharmacokinetics, and efficacy of oral torezolid phosphate in patients with complicated skin and skin structure infections. 
  • Phase II, randomized, double-blind, multicenter study comparing the safety and pharmacokinetics of tefibazumab to placebo for treatment of Staphylococcus aureus bacteremia. 
  • Phase II, randomized, multicenter, double-blind, placebo-controlled trial of a polyclonal anti-Staphylococcus aureus capsular polysaccharide immune globulin in treatment of Staphylococcus aureus bacteremia. 
  • Phosphatidylglycerol homeostasis in glycerol-phosphate auxotrophs of Staphylococcus aureus. 
  • Point-of-care antimicrobial coating protects orthopaedic implants from bacterial challenge. 
  • Polymorphisms in Fibronectin Binding Proteins A and B among Staphylococcus aureus Bloodstream Isolates Are Not Associated with Arthroplasty Infection. 
  • Polymorphisms in HLA Class II Genes Are Associated With Susceptibility to Staphylococcus aureus Infection in a White Population. 
  • Polymorphisms in fibronectin binding protein A of Staphylococcus aureus are associated with infection of cardiovascular devices. 
  • Pooled analysis of the phase 3 REVIVE trials: randomised, double-blind studies to evaluate the safety and efficacy of iclaprim versus vancomycin for treatment of acute bacterial skin and skin-structure infections. 
  • Poor functional status as a risk factor for surgical site infection due to methicillin-resistant Staphylococcus aureus. 
  • Porcine necrotizing staphylococcal endometritis. 
  • Postoperative bacteremia secondary to surgical site infection. 
  • Postoperative infection following strabismus surgery: case series and increased incidence in a single referral center. 
  • Potential associations between hematogenous complications and bacterial genotype in Staphylococcus aureus infection. 
  • Potential associations between severity of infection and the presence of virulence-associated genes in clinical strains of Staphylococcus aureus. 
  • Potential role for telavancin in bacteremic infections due to gram-positive pathogens: focus on Staphylococcus aureus. 
  • Povidone-iodine to prevent ophthalmia neonatorum. 
  • Presence of genes encoding panton-valentine leukocidin is not the primary determinant of outcome in patients with hospital-acquired pneumonia due to Staphylococcus aureus. 
  • Prevalence of infective endocarditis in patients with Staphylococcus aureus bacteraemia: the value of screening with echocardiography. 
  • Probe directed at a segment of Rickettsia rickettsii rRNA amplified with polymerase chain reaction. 
  • Probing of the cis-5-phenyl proline scaffold as a platform for the synthesis of mechanism-based inhibitors of the Staphylococcus aureus sortase SrtA isoform. 
  • Prognostic factors in 61 cases of Staphylococcus aureus prosthetic valve infective endocarditis from the International Collaboration on Endocarditis merged database. 
  • Quality control limits for ampicillin, carbenicillin, mezlocillin, and piperacillin disk diffusion susceptibility tests: a collaborative study. 
  • RNA-guided transcriptional silencing in vivo with S. aureus CRISPR-Cas9 repressors. 
  • RP 59500, a new streptogramin highly active against recent isolates of North American staphylococci. 
  • Rapid Antimicrobial Susceptibility Testing Using Forward Laser Light Scatter Technology. 
  • Rare cause of back pain: Staphylococcus aureus vertebral osteomyelitis complicated by recurrent epidural abscess and severe sepsis. 
  • Reactive oxygen species induce antibiotic tolerance during systemic Staphylococcus aureus infection. 
  • Recalcitrant rhinosinusitis, innate immunity, and mannose-binding lectin. 
  • Recurrent Staphylococcus aureus bacteremia: pulsed-field gel electrophoresis findings in 29 patients. 
  • Redox regulation of mitophagy in the lung during murine Staphylococcus aureus sepsis. 
  • Reduced susceptibility of Staphylococcus aureus to vancomycin and platelet microbicidal protein correlates with defective autolysis and loss of accessory gene regulator (agr) function. 
  • Reduced valve replacement surgery and complication rate in Staphylococcus aureus endocarditis patients receiving acetyl-salicylic acid. 
  • Relationship between Vancomycin MIC and Virulence Gene Expression in Clonal Complexes of Methicillin-Susceptible Staphylococcus aureus Strains Isolated from Left-Sided Endocarditis. 
  • Repeat infective endocarditis: differentiating relapse from reinfection. 
  • Results from a 13-Year Prospective Cohort Study Show Increased Mortality Associated with Bloodstream Infections Caused by Pseudomonas aeruginosa Compared to Other Bacteria. 
  • Rhythmic bacterial susceptibility to antibiotics at a large hospital. 
  • Rifampicin for Staphylococcus aureus bacteraemia: give it ARREST. 
  • Risk Factors for Recurrent Staphylococcus aureus Bacteremia. 
  • Risk factors for Staphylococcus aureus nasal colonization in Danish middle-aged and elderly twins. 
  • Risk factors for hematogenous complications of intravascular catheter-associated Staphylococcus aureus bacteremia. 
  • Risk factors for pediatric ventriculoperitoneal shunt infection and predictors of infectious pathogens. 
  • Risk factors for postoperative mediastinitis due to methicillin-resistant Staphylococcus aureus. 
  • Risk of endocarditis among patients with prosthetic valves and Staphylococcus aureus bacteremia. 
  • Risk prediction for Staphylococcus aureus surgical site infection following cardiothoracic surgery; A secondary analysis of the V710-P003 trial. 
  • Role of complement receptors 1 and 2 (CD35 and CD21), C3, C4, and C5 in survival by mice of Staphylococcus aureus bacteremia. 
  • Role of echocardiography in evaluation of patients with Staphylococcus aureus bacteremia: experience in 103 patients. 
  • Role of the heat shock protein 90 in immune response stimulation by bacterial DNA and synthetic oligonucleotides. 
  • SHEA neonatal intensive care unit (NICU) white paper series: Practical approaches to Staphylococcus aureus disease prevention. 
  • Segrosome structure revealed by a complex of ParR with centromere DNA. 
  • Selection of TCR V alpha by MHC class II predicts superantigen reactivity. 
  • Selection of strains for quality assessment of the disk induction method for detection of inducible clindamycin resistance in Staphylococci: a CLSI collaborative study. 
  • Selective use of intranasal mupirocin and chlorhexidine bathing and the incidence of methicillin-resistant Staphylococcus aureus colonization and infection among intensive care unit patients. 
  • Serious infection after acute myocardial infarction: incidence, clinical features, and outcomes. 
  • Serum dilution test for bactericidal activity. I. Selection of a physiologic diluent. 
  • Serum dilution test for bactericidal activity. II. Standardization and correlation with antimicrobial assays and susceptibility tests. 
  • Severe surgical site infection in community hospitals: epidemiology, key procedures, and the changing prevalence of methicillin-resistant Staphylococcus aureus. 
  • Sortase-catalyzed initiator attachment enables high yield growth of a stealth polymer from the C terminus of a protein. 
  • Specificity and immunochemical properties of antibodies to bacterial DNA in sera of normal human subjects and patients with systemic lupus erythematosus (SLE). 
  • Sphaerostilbellins, New Antimicrobial Aminolipopeptide Peptaibiotics from Sphaerostilbella toxica. 
  • Staphylococcal surgical site infections. 
  • Staphylococcus aureus Bacteremia Among Patients Receiving Maintenance Hemodialysis: Trends in Clinical Characteristics and Outcomes. 
  • Staphylococcus aureus bacteraemia in a tropical setting: patient outcome and impact of antibiotic resistance. 
  • Staphylococcus aureus bacteremia after median sternotomy: clinical utility of blood culture results in the identification of postoperative mediastinitis. 
  • Staphylococcus aureus bacteremia among elderly vs younger adult patients: comparison of clinical features and mortality. 
  • Staphylococcus aureus bacteremia among patients with health care-associated fever. 
  • Staphylococcus aureus bacteremia and endocarditis. 
  • Staphylococcus aureus bacteremia and endocarditis. 
  • Staphylococcus aureus bacteremia at 5 US academic medical centers, 2008-2011: significant geographic variation in community-onset infections. 
  • Staphylococcus aureus bacteremia in patients with neutropenia. 
  • Staphylococcus aureus bacteremia in patients with permanent pacemakers or implantable cardioverter-defibrillators. 
  • Staphylococcus aureus bacteremia in patients with prosthetic devices: costs and outcomes. 
  • Staphylococcus aureus bloodstream infection: a pooled analysis of five prospective, observational studies. 
  • Staphylococcus aureus bloodstream infections: definitions and treatment. 
  • Staphylococcus aureus endocarditis: The Grady Memorial Hospital Experience. 
  • Staphylococcus aureus endocarditis: a consequence of medical progress. 
  • Staphylococcus aureus evades lysozyme-based peptidoglycan digestion that links phagocytosis, inflammasome activation, and IL-1beta secretion. 
  • Staphylococcus aureus fatty acid auxotrophs do not proliferate in mice. 
  • Staphylococcus aureus infections: epidemiology, pathophysiology, clinical manifestations, and management. 
  • Staphylococcus aureus native valve infective endocarditis: report of 566 episodes from the International Collaboration on Endocarditis Merged Database. 
  • Staphylococcus aureus pericardial abscess in a patient with liver cirrhosis: case report. 
  • Staphylococcus aureus secretes immunomodulatory RNA and DNA via membrane vesicles. 
  • Staphylococcus aureus sepsis and mitochondrial accrual of the 8-oxoguanine DNA glycosylase DNA repair enzyme in mice. 
  • Staphylococcus aureus sepsis induces early renal mitochondrial DNA repair and mitochondrial biogenesis in mice. 
  • Staphylococcus aureus sortase A contributes to the Trojan horse mechanism of immune defense evasion with its intrinsic resistance to Cys184 oxidation. 
  • Staphylococcus aureus sortase transpeptidase SrtA: insight into the kinetic mechanism and evidence for a reverse protonation catalytic mechanism. 
  • Structural and biochemical characterization of MepR, a multidrug binding transcription regulator of the Staphylococcus aureus multidrug efflux pump MepA. 
  • Structural basis for cooperative DNA binding by two dimers of the multidrug-binding protein QacR. 
  • Structural mechanism of Staphylococcus aureus Hfq binding to an RNA A-tract. 
  • Structural mechanism of the simultaneous binding of two drugs to a multidrug-binding protein. 
  • Structural mechanism of transcription regulation of the Staphylococcus aureus multidrug efflux operon mepRA by the MarR family repressor MepR. 
  • Structural mechanisms of QacR induction and multidrug recognition. 
  • Structure and filament dynamics of the pSK41 actin-like ParM protein: implications for plasmid DNA segregation. 
  • Structures of the pleiotropic translational regulator Hfq and an Hfq-RNA complex: a bacterial Sm-like protein. 
  • Subtractive cloning: new genes for studying inflammatory disorders. 
  • Superficial genitourinary abscesses in children: emergence of methicillin resistant Staphylococcus aureus. 
  • Suppression of conformational heterogeneity at a protein-protein interface. 
  • Surgical-site infection due to Staphylococcus aureus among elderly patients: mortality, duration of hospitalization, and cost. 
  • Surveillance of iclaprim activity: In vitro susceptibility of gram-positive pathogens collected from 2012 to 2014 from the United States, Asia Pacific, Latin American and Europe. 
  • Surveillance of iclaprim activity: in vitro susceptibility of Gram-positive skin infection pathogens collected from 2015 to 2016 from North America and Europe. 
  • Survival Benefit of Empirical Therapy for Staphylococcus aureus Bloodstream Infections in Infants. 
  • Susceptibility of ePTFE vascular grafts and bioengineered human acellular vessels to infection. 
  • Synthesis and evaluation of cyclopentane-based muraymycin analogs targeting MraY. 
  • Tailoring nitric oxide release with additive manufacturing to create antimicrobial surfaces. 
  • Telavancin for hospital-acquired pneumonia: clinical response and 28-day survival. 
  • Telavancin for the treatment of hospital-acquired pneumonia: findings from the ATTAIN studies. 
  • The Skin Commensal Yeast Malassezia globosa Thwarts Bacterial Biofilms to Benefit the Host. 
  • The deadly toll of invasive methicillin-resistant Staphylococcus aureus infection in community hospitals. 
  • The effect of burn wound surgery and teicoplanin on the bactericidal activity of polymorphonuclear leucocytes against Staphylococcus aureus. 
  • The intercellular adhesin locus ica is present in clinical isolates of Staphylococcus aureus from bacteremic patients with infected and uninfected prosthetic joints. 
  • The lipid lysyl-phosphatidylglycerol is present in membranes of Rhizobium tropici CIAT899 and confers increased resistance to polymyxin B under acidic growth conditions. 
  • The molecular mechanisms of allosteric mutations impairing MepR repressor function in multidrug-resistant strains of Staphylococcus aureus. 
  • The potential for community exposures to pathogens from an urban dairy. 
  • The smart activatable P2&3TT probe allows accurate, fast, and highly sensitive detection of Staphylococcus aureus in clinical blood culture samples. 
  • The staphylococcal QacR multidrug regulator binds a correctly spaced operator as a pair of dimers. 
  • The statistical conformation of a highly flexible protein: small-angle X-ray scattering of S. aureus protein A. 
  • Three-in-one chromatography-free purification, tag removal, and site-specific modification of recombinant fusion proteins using sortase A and elastin-like polypeptides. 
  • Time series analysis of rhythmic bacterial resistance development to antibiotics. 
  • Titrating T-cell epitopes within self-assembled vaccines optimizes CD4+ helper T cell and antibody outputs. 
  • Treatment of methicillin-resistant staphylococcus aureus infections with quinupristin-dalfopristin in patients intolerant of or failing prior therapy. For the Synercid Emergency-Use Study Group. 
  • Two genes on A/J chromosome 18 are associated with susceptibility to Staphylococcus aureus infection by combined microarray and QTL analyses. 
  • Two-dimensional global longitudinal strain is superior to left ventricular ejection fraction in prediction of outcome in patients with left-sided infective endocarditis. 
  • United States geographic bacteria susceptibility patterns. 1996 ASCP Susceptibility Testing Group. American Society of Clinical Pathologists. 
  • Use of a simple criteria set for guiding echocardiography in nosocomial Staphylococcus aureus bacteremia. 
  • Use of vancomycin or first-generation cephalosporins for the treatment of hemodialysis-dependent patients with methicillin-susceptible Staphylococcus aureus bacteremia. 
  • Variation in the type and frequency of postoperative invasive Staphylococcus aureus infections according to type of surgical procedure. 
  • Vascular access infections in patients undergoing dialysis with special emphasis on the role and treatment of Staphylococcus aureus. 
  • Venous thrombosis in patients with short- and long-term central venous catheter-associated Staphylococcus aureus bacteremia. 
  • Vinyl sulfones: inhibitors of SrtA, a transpeptidase required for cell wall protein anchoring and virulence in Staphylococcus aureus. 
  • Virulence of endemic nonpigmented northern Australian Staphylococcus aureus clone (clonal complex 75, S. argenteus) is not augmented by staphyloxanthin. 
  • Where does a Staphylococcus aureus vaccine stand? 
  • Whole-genome sequencing of bloodstream Staphylococcus aureus isolates does not distinguish bacteraemia from endocarditis. 
  • [In vitro studies on antioxidant and antimicrobial activities of polysaccharide from Lycoris aurea]. 
  • [Staphylococcus aureus infections: new challenges from an old pathogen]. 
  • “A robust platform for the synthesis of new tetracycline antibiotics 
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  Keywords of People

  • Middleton, John Paul, Professor of Medicine, Medicine, Nephrology
  • Reed, Shelby Derene, Professor in Population Health Sciences, Duke Science & Society
  • Tsalik, Ephraim, Adjunct Associate Professor in the Department of Medicine, Medicine, Infectious Diseases