Steroids

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  Subject Areas on Research

  • A perspective for understanding the modes of juvenile hormone action as a lipid signaling system. 
  • A systematic approach to mapping recessive disease genes in individuals from outbred populations. 
  • A timecourse analysis of systemic and gonadal effects of temperature on sexual development of the red-eared slider turtle Trachemys scripta elegans. 
  • Actions of glucocorticosteroids on ischemic-reperfused muscle and cutaneous tissue. 
  • Adverse events associated with fluoroscopically guided lumbosacral transforaminal epidural steroid injections. 
  • An Embryonic and Induced Pluripotent Stem Cell Model for Ovarian Granulosa Cell Development and Steroidogenesis. 
  • Anaphylactic reactions to neuromuscular blocking drugs: are we making the correct diagnosis? 
  • Androgen and estrogen treatment, alone or in combination, differentially influences bone maturation and hypothalamic mechanisms that time puberty in the male rhesus monkey (Macaca mulatta). 
  • Arteritis with impaired renal function. 
  • Association of tocolytic therapy with antenatal steroid administration and infant outcomes. Newborn Lung Project. 
  • Avascular necrosis following bone marrow transplantation: a case-control study. 
  • Belatacept and sirolimus prolong nonhuman primate islet allograft survival: adverse consequences of concomitant alefacept therapy. 
  • Biologics in organ transplantation. 
  • Bone marrow B cell precursor number after allogeneic stem cell transplantation and GVHD development. 
  • CT Fluoroscopy-Guided Interlaminar Epidural Steroid Injections in the Cervical Spine: Rate of Nontarget Injection Into the Retrodural Space of Okada. 
  • CT fluoroscopy-assisted cervical transforaminal steroid injection: tips, traps, and use of contrast material. 
  • CT fluoroscopy-guided cervical interlaminar steroid injections: safety, technique, and radiation dose parameters. 
  • CT-guided cervical transforaminal steroid injections: where should the needle tip be located? 
  • CYP7B1: one cytochrome P450, two human genetic diseases, and multiple physiological functions. 
  • Cataracts after bone marrow transplantation: long-term follow-up of adults treated with fractionated total body irradiation. 
  • Changes in mortality and morbidities among infants born at less than 25 weeks during the post-surfactant era. 
  • Clinical impact of stress dose steroids in patients with septic shock: insights from the PROWESS-Shock trial. 
  • Clinical trials: where are we now? 
  • Coaxial continuous flow fast atom bombardment in conjunction with tandem mass spectrometry for the analysis of biomolecules. 
  • Collapsing glomerulopathy in 19 patients with systemic lupus erythematosus or lupus-like disease. 
  • Comparable effectiveness of caudal vs. trans-foraminal epidural steroid injections. 
  • Comparison of four different immunosuppression protocols without long-term steroid therapy in kidney recipients monitored by surveillance biopsy: five-year outcomes. 
  • Complete response to steroids in dural inflammatory pseudotumor associated with Still's disease. 
  • Consensus treatments for moderate juvenile dermatomyositis: beyond the first two months. Results of the second Childhood Arthritis and Rheumatology Research Alliance consensus conference. 
  • Contralateral radiculopathy after transforaminal lumbar interbody fusion. 
  • Crohn's disease patients' risk-benefit preferences: serious adverse event risks versus treatment efficacy. 
  • Current management of pediatric inflammatory bowel disease. 
  • Differential changes in steroid hormones before competition in bonobos and chimpanzees. 
  • Diterpenoid, steroid, and triterpenoid agonists of liver X receptors from diversified terrestrial plants and marine sources. 
  • Editorial comment. The value of intensive medical management of distal ureteral calculi in an effort to facilitate spontaneous stone passage. 
  • Effect of Body Habitus on Radiation Dose During CT Fluoroscopy-Guided Spine Injections. 
  • Effect of sulphanilamide on formation of sterols in Saccharomyces cerevisiae and Neurospora crassa. 
  • Effects of prenatal treatment with antiandrogens on luteinizing hormone secretion and sex steroid concentrations in adult spotted hyenas, Crocuta crocuta. 
  • Efficacy of intranasal corticosteroids for acute sinusitis. 
  • Embryonic expression and steroid regulation of brain aromatase cyp19a1b in zebrafish (Danio rerio). 
  • Endocardial and epicardial steroid lead pacing in the neonatal and paediatric age group. 
  • Erosive spinal tophus in a patient with gout and back pain. 
  • Familial Bell's palsy. 
  • Fasting-induced hepatic production of DHEA is regulated by PGC-1alpha, ERRalpha, and HNF4alpha. 
  • Final results of a study of escalating doses of hyperfractionated radiotherapy in brain stem tumors in children: a Pediatric Oncology Group study. 
  • Genetic ablation of the steroid receptor coactivator-ubiquitin ligase, E6-AP, results in tissue-selective steroid hormone resistance and defects in reproduction. 
  • Gipr is essential for adrenocortical steroidogenesis; however, corticosterone deficiency does not mediate the favorable metabolic phenotype of Gipr(-/-) mice. 
  • Graft survival in a rhesus renal transplant model after immunotoxin-mediated T-cell depletion is enhanced by mycophenolate and steroids. 
  • Guidelines for treatment of decompression illness. 
  • HLA-DQA1 and APOL1 as Risk Loci for Childhood-Onset Steroid-Sensitive and Steroid-Resistant Nephrotic Syndrome. 
  • HLA-DQA1 and PLCG2 Are Candidate Risk Loci for Childhood-Onset Steroid-Sensitive Nephrotic Syndrome. 
  • Hydrocortisone inhibits mucin secretion from guinea pig gallbladder. 
  • Identification of metabolities of progesterone-4-14C in domestic sow urine. 
  • Immune reconstitution syndrome in a patient with disseminated histoplasmosis and steroid taper: maintaining the perfect balance. 
  • Immunology of inflammatory bowel disease: summary of the proceedings of the Subcommittee on Immunosuppressive Use in IBD. 
  • Impact of Intraoperative Steroids on Postoperative Infection Rates and Length of Hospital Stay: A Study of 1200 Spine Surgery Patients. 
  • Inadvertent Intrafacet Injection during Lumbar Interlaminar Epidural Steroid Injection: A Comparison of CT Fluoroscopic and Conventional Fluoroscopic Guidance. 
  • Inhaled steroids as prophylaxis for delayed pulmonary toxicity syndrome in breast cancer patients undergoing high-dose chemotherapy and autologous stem cell transplantation. 
  • Inhibition of complement, evoked antibody, and cellular response prevents rejection of pig-to-primate cardiac xenografts. 
  • Isolated beta-adrenergic binding sites: a potential assay vehicle for catecholamines. 
  • Kerma area product method for effective dose estimation during lumbar epidural steroid injection procedures: phantom study. 
  • Long-term outcome of early steroid withdrawal after kidney transplantation in African American recipients monitored by surveillance biopsy. 
  • Management patterns of childhood-onset nephrotic syndrome. 
  • Mitochondrial benzodiazepine receptors regulate steroid biosynthesis. 
  • Multiple etiologies of tumor hypoxia require multifaceted solutions. 
  • Mutational analysis of NPHS2 and WT1 in frequently relapsing and steroid-dependent nephrotic syndrome. 
  • Neuroactive steroids and PTSD treatment. 
  • Neuroactive steroids are altered in schizophrenia and bipolar disorder: relevance to pathophysiology and therapeutics. 
  • Novel 17 alpha-chloro-17 beta-sulfinyl steroids as specific inhibitors of sebaceous gland activity: potential antiacne agents. 
  • Novel therapeutic approaches for thrombotic thrombocytopenic purpura. 
  • Obesity following kidney transplantation and steroid avoidance immunosuppression. 
  • Occipital Headache in Chronic Lymphocytic Inflammation With Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS). 
  • On eating poison ivy. 
  • Optimal contrast concentration for CT-guided epidural steroid injections. 
  • Origins of fecal neutral steroids in rats. 
  • Participation in weight-related sports is associated with higher use of unhealthful weight-control behaviors and steroid use. 
  • Pericardial pseudoeffusion due to steroid-induced lipomatosis. 
  • Peripheral nerve entrapment due to steroid-induced lipomatosis of the popliteal fossa. Case report. 
  • Peripheral vascular complications during transcatheter aortic valve replacement: management and potential role of chronic steroid use. 
  • Phylogenetic comparisons implicate sex hormone-binding globulin in "masculinization" of the female spotted hyena (Crocuta crocuta). 
  • Pregnancy and adrenocortical function; endocrine studies of pregnancy occurring in two adrenal-deficient women. 
  • Radiation dose exposure for lumbar spine epidural steroid injections: a comparison of conventional fluoroscopy data and CT fluoroscopy techniques. 
  • Radiation therapy for renal transplant rejection refractory to pulse steroids and OKT3. 
  • Regulation of the dynamics of hsp90 action on the glucocorticoid receptor by acetylation/deacetylation of the chaperone. 
  • Resolution of innumerable cerebral Nocardia paucivorans abscesses after medical management. 
  • Ritterazine B, a new cytotoxic natural compound, induces apoptosis in cancer cells. 
  • Role of cyclic AMP in the actions of luteinizing hormone on steroidogenesis in the corpus luteum. 
  • Self-presentation can be hazardous to your health: impression management and health risk. 
  • Serum cartilage oligomeric matrix protein (COMP) level is a marker of disease activity in relapsing polychondritis. 
  • Sex differences in cocaine-stimulated motor behavior: disparate effects of gonadectomy. 
  • Simultaneous quantification of GABAergic 3alpha,5alpha/3alpha,5beta neuroactive steroids in human and rat serum. 
  • Simultaneous quantitation of multiple contraceptive hormones in human serum by LC-MS/MS. 
  • Specific podocin mutations correlate with age of onset in steroid-resistant nephrotic syndrome. 
  • Steroid hormone regulation of specific gene expression. 
  • Steroid secretion and testosterone binding in a woman with an ovarian hilus cell tumor and thyrotoxicosis. 
  • Steroid structural requirements for high affinity binding to human sex steroid binding protein (SBP). 
  • Steroid treatment for myasthenia gravis: steroids have an important role. 
  • Steroidal and triterpenoidal fungal metabolites as ligands of liver X receptors. 
  • Steroidogenesis in porcine atretic follicles: loss of aromatase activity in isolated granulosa and theca. 
  • Steroidogenic factor-1 is a sphingolipid binding protein. 
  • Steroids for restenosis: strike three! 
  • Stimulation of cholesterogenesis by ascorbic acid in adrenal of rats fed vitamin A. 
  • Technique for CT fluoroscopy-guided cervical interlaminar steroid injections. 
  • Tendinitis and other chronic tendinopathies. 
  • Testis ecdysiotropin, an insect gonadotropin that induces synthesis of ecdysteroid. 
  • The effect of angiostatic steroids and beta-cyclodextrin tetradecasulfate on corneal neovascularization in the rat. 
  • The higher affinity of human type 1 3beta-hydroxysteroid dehydrogenase (3beta-HSD1) for substrate and inhibitor steroids relative to human 3beta-HSD2 is validated in MCF-7 tumor cells and related to subunit interactions. 
  • The mechanism of action of steroid hormones: a new twist to an old tale. 
  • The peripheral-type benzodiazepine receptor is functionally linked to Leydig cell steroidogenesis. 
  • The predominance of membranoproliferative glomerulonephritis in childhood nephrotic syndrome in Ibadan, Nigeria. 
  • The subcellular localization of syntaxin 17 varies among different cell types and is altered in some malignant cells. 
  • Thin-layer and gas--liquid chromatographic identification of neutral steroids in human and rat feces. 
  • Treatment of osteonecrosis of the femoral head with free vascularized fibular grafting. A long-term follow-up study of one hundred and three hips. 
  • Treatment of steroid-refractory acute graft-versus-host disease with anti-CD147 monoclonal antibody ABX-CBL. 
  • Unique response profile of trabecular meshwork cells to the novel selective glucocorticoid receptor agonist, GW870086X. 
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  Keywords of People

  • McDonnell, Donald Patrick, Chair, Department of Pharmacology & Cancer Biology, Duke Innovation & Entrepreneurship
  • McLendon, Roger Edwin, Professor of Pathology, Pathology
  • Sampson, John Howard, Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine, Immunology