Stimulation, Chemical

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  Subject Areas on Research

  • A comparison of chemical and electrical synaptic transmission between single sensory cells and a motoneurone in the central nervous system of the leech. 
  • A major role for the EP4 receptor in regulation of renin. 
  • ACTH-receptor interaction in the adrenal: a model for the initial step in the action of hormones that stimulate adenyl cyclase. 
  • Acidic stimuli activates two distinct pathways in taste receptor cells from rat fungiform papillae. 
  • Adenosine 3',5'-monophosphate (cyclic AMP) as the mediator of the actions of melanocyte stimulating hormone (MSH) and norepinephrine on the frog skin. 
  • Adenylate cyclase-coupled beta adrenergic receptors effect of membrane lipid-perturbing agents on receptor binding and enzyme stimulation by catecholamines. 
  • Altered activity of the nucleotide regulatory site in the parathyroid hormone-sensitive adenylate cyclase from the renal cortex of a patient with pseudohypoparathyroidism. 
  • An inhibitory role for brain serotonin-containing systems in the locomotor effects of d-amphetamine. 
  • Augmentation of cardiac contractility mediated by the human beta(3)-adrenergic receptor overexpressed in the hearts of transgenic mice. 
  • Binding, coupling, and mRNA subtype heterogeneity of alpha 1-adrenergic receptors in cultured human RPE. 
  • Both insulin and epidermal growth factor stimulate lipogenesis and acetyl-CoA carboxylase activity in isolated adipocytes. Importance of homogenization procedure in avoiding artefacts in acetyl-CoA carboxylase assay. 
  • CHEMICAL STIMULATION OF RED NUCLEUS, SUBSTANTIA NIGRA, AND BASIS PEDUNCULI IN ALERT CATS. 
  • Canine bombesin-like gastrin releasing peptides stimulate gastrin release and acid secretion in the dog. 
  • Cellular anti-GP120 cytolytic reactivities in HIV-1 seropositive individuals. 
  • Characterization of the calcium response to thyrotropin-releasing hormone (TRH) in cells transfected with TRH receptor complementary DNA: importance of voltage-sensitive calcium channels. 
  • Chemical stimulation of telencephalon, diencephalon and mesencephalon in understrained animals. 
  • Cholinergic stimulation of phosphatidic acid formation by rat cornea in vitro. 
  • Cholinergic stimulation of phosphatidylinositol hydrolysis by rat corneal epithelium in vitro. 
  • Clonazepam-induced up-regulation of serotonin1 binding sites in frontal cortex of rat. 
  • Clozapine markedly elevates pregnenolone in rat hippocampus, cerebral cortex, and serum: candidate mechanism for superior efficacy? 
  • Coding in the mammalian gustatory system. 
  • Commentary. Molecular pharmacology of beta-adrenergic receptors--a status report. 
  • Compartmental analysis of amine storage in bovine adrenal medullary granules. 
  • Concerning the mechanism of FSH action: rapid stimulation of testicular synthesis of nuclear RNA. 
  • Conditioned changes in appetitive and consummatory responses to flavors paired with oral or nutrient reinforcement among adult rats. 
  • Cryopreservation: the problem of evaluation. 
  • Defective phorbol ester-stimulated secretion of beta-amyloid precursor protein from Alzheimer's disease fibroblasts. 
  • Desensitization of beta-adrenergic stimulated adenylate cyclase in turkey erythrocytes. 
  • Development of central control of norepinephrine turnover and release in the rat heart: responses to tyramine, 2-deoxyglucose and hydralazine. 
  • Drug-resistant effect of adenine nucleotides and magnesium on catecholamine efflux from isolated adrenal medullary storage vesicles. 
  • Dynamic and multimodal responses of gustatory cortical neurons in awake rats. 
  • Editorial: Smoking, catecholamines, and the heart. 
  • Effect of 5-hydroxytryptamine1 serotonin receptor agonists on noxiously stimulated micturition in cats with chronic spinal cord injury. 
  • Effect of basic fibroblast growth factor on angiogenesis and growth of isografted bone: quantitative in vitro-in vivo analysis in mice. 
  • Effect of cooling on the responsiveness of canine tracheal muscle. 
  • Effect of cyclic adenosine 3',5'-monophosphate on the incorporation of 3H-leucine into polypeptides by beef thyroid polysomes in vitro. 
  • Effect of cyclic nucleotides on the induction of ornithine decarboxylase in BHK cells by serum and insulin. 
  • Effect of growth conditions on the activity of ornithine decarboxylase in cultured hepatoma cells. I. Effect of amino acid supply. 
  • Effect of growth conditions on the activity of ornithine decarboxylase in cultured hepatoma cells. II. Effect of serum and insulin. 
  • Effect of increased intracranial pressure on gastric acid secretion. 
  • Effects of ZD6169, a K ATP channel opener, on neurally-mediated plasma extravasation in the rat urinary bladder induced by chemical or electrical stimulation of nerves. 
  • Effects of chronic chlorisondamine administration on the sympatho-adrenal axis. 
  • Effects of vitamin A and phenobarbital on liver endoplasmic reticulum of rats. 
  • Efficacy and safety of ganirelix acetate versus leuprolide acetate in women undergoing controlled ovarian hyperstimulation. 
  • Epithelial responses of rabbit tongues and their involvement in taste transduction. 
  • Expression of cytokine mRNA in murine splenic dendritic cells and better induction of T cell-derived cytokines by dendritic cells than by macrophages during in vitro costimulation assay using specific antigens. 
  • Facilitatory effects of 4-aminopyridine on normal neuromuscular transmission. 
  • Food reward in the absence of taste receptor signaling. 
  • Functional expression of human 5-HT1A receptors and differential coupling to second messengers in CHO cells. 
  • Glutamate acting at NMDA receptors stimulates embryonic cortical neuronal migration. 
  • Gonadotropin release in patients with androgen insensitivity. Testicular feminization syndrome. 
  • Growth retardation in the Lesch-Nyhan syndrome. 
  • Hemodynamic changes during hemodialysis: role of dialyzate. 
  • Hemodynamic evaluation of glucagon in symptomatic heart disease. 
  • Heterogeneity of adenylate cyclase-coupled beta-adrenergic receptors. 
  • Hydrocortisone inhibits mucin secretion from guinea pig gallbladder. 
  • Impaired lymphocyte transformation in Hodgkin's disease. Evidence for depletion of circulating t-lymphocytes. 
  • Impaired second phase insulin response of diabetes-prone C57BL/6J mouse islets. 
  • In vitro modulation of macrophage tumoricidal activity: partial characterization of a macrophage-activating factor(s) in supernatants of NaIO4-treated peritoneal cells. 
  • In vitro stimulation of alkaline phosphatase activity in immature embryonic chick pelvic cartilage by adenosine 3'5'-monophosphate. 
  • Inhibition of premature labor: a multicenter comparison of ritodrine and ethanol. 
  • Inhibitory action of a new sympathomimetic amino (DU-21220) on the nongravid uterus. 
  • Interactions between salt and acid stimuli: a lesson in gustation from simultaneous epithelial and neural recordings. 
  • Intercycle variability of day 3 follicle-stimulating hormone levels and its effect on stimulation quality in in vitro fertilization. 
  • Interferon gamma (IFNgamma) gene transfer of an EMT6 tumor that is poorly responsive to IFNgamma stimulation: increase in tumor immunogenicity is accompanied by induction of a mouse class II transactivator and class II MHC. 
  • Interferon-gamma and tumour necrosis factor induce expression of major histocompatibility complex antigen on rat retinal astrocytes. 
  • Ionotropic and metabotropic receptors, protein kinase A, protein kinase C, and Src contribute to C-fiber-induced ERK activation and cAMP response element-binding protein phosphorylation in dorsal horn neurons, leading to central sensitization. 
  • Isolation of protein factors from oviduct polysomes which stimulate protein synthesis. 
  • Lysophosphatidic acid stimulates neurotransmitter-like conductance changes that precede GABA and L-glutamate in early, presumptive cortical neuroblasts. 
  • Maturation of sympathetic neurotransmission in the rat heart. I. Ontogeny of the synaptic vesicle uptake mechanism and correlation with development of synaptic function. Effects of neonatal methadone administration on development of synaptic vesicles. 
  • Maturation of sympathetic neurotransmission in the rat heart. II. Enhanced development of presynaptic and postsynaptic components of noradrenergic synapses as a result of neonatal hyperthyroidism. 
  • Mechanism of estrogen action: early transcriptional and translational events. 
  • Mice lacking the dopamine transporter display altered regulation of distal colonic motility. 
  • Monoamine mediation of cocaine-induced hypothalamo-pituitary-adrenal activation. 
  • NADPH-dependent oxygen reductase activity in pulmonary macrophages. 
  • Neural responses to bitter compounds in rats. 
  • Neuronal localization of the enhanced adenylate cyclase responsiveness to catecholamines in the rat cerebral cortex following reserpine injections. 
  • Pathogenesis of duodenal ulcer. Gastric hyperacidity caused by propionitrile and cysteamine in rats. 
  • Peroxide detoxification affecting the production of immunoglobulin by mouse myeloma tumor cells in vitro. 
  • Pharmacologic activation of the human coronary microcirculation in vitro: endothelium-dependent dilation and differential responses to acetylcholine. 
  • Pharmacological stimulation of the cholinergic antiinflammatory pathway. 
  • Phorbol myristate acetate stimulates pinocytosis and membrane spreading in mouse peritoneal macrophages. 
  • Physiologic impairment of olfactory stimulus processing in schizophrenia. 
  • Physiological receptors as physicochemical entities. 
  • Pineal beta adrenergic receptor: correlation of binding of 3H-l-alprenolol with stimulation of adenylate cyclase. 
  • Pituitary adenylate cyclase-activating polypeptide stimulates secretion in T84 cells. 
  • Postsynaptic effect of La3+ at the frog neuromuscular junction. 
  • Pregnenolone-sulfate: an endogenous antagonist of the gamma-aminobutyric acid receptor complex in brain? 
  • Prenatal reserpine administration: permanent changes in adrenal tyrosine hydroxylase and dopamine beta-hydroxylase. 
  • Protein biosynthesis in the testis. 3. Dual effect of glucose. 
  • Protein biosynthesis in the testis. I. Comparison between stimulation by FSH and glucose. 
  • Protein biosynthesis in the testis. II. Role of adenosine triphosphate (ATP) in stimulation by glucose. 
  • Protein biosynthesis in the testis. V. Concerning the mechanism of stimulation by follicle-stimulating hormone. 
  • Protein biosynthesis on chick oviduct polyribosomes. I. Changes during estrogen-mediated tissue differentiation. 
  • Protein biosynthesis on chick oviduct polyribosomes. II. Regulation by progesterone. 
  • Protein kinase C: cellular target of the second messenger arachidonic acid? 
  • RNA synthesis in liver nuclei of young rats fed varying amounts of vitamin A. 
  • Rates of induction of specific translatable messenger RNAs for ovalbumin and avidin by steroid hormones. 
  • Real-time three-dimensional echocardiography to construct clinically ready, load-independent indices of myocardial contractile performance. 
  • Regulation of the prostaglandin enzymatic system by estradiol and progesterone in nonpregnant sheep cervix. 
  • Respiratory and telencephalic modulation of vocal motor neurons in the zebra finch. 
  • Sensitizing effects of leukotriene B4 on intradental primary afferents. 
  • Serotonergic cell signaling in an animal model of aging and depression: olfactory bulbectomy elicits different adaptations in brain regions of young adult vs aging rats. 
  • Simultaneous monitoring of tissue PO2 and NADH fluorescence during synaptic stimulation and spreading depression reveals a transient dissociation between oxygen utilization and mitochondrial redox state in rat hippocampal slices. 
  • Steroid hormone induction of a specific translatable messenger RNA. 
  • Stimulation of endothelial cell prostacyclin release by retina-derived factors. 
  • Stimulation of secretion by the T84 colonic epithelial cell line with dietary flavonols. 
  • Structural and functional response of toad urinary bladder to LiCl. 
  • Studies on mode of action of vitamin A. 
  • Substituting ornithine for arginine in total parenteral nutrition eliminates enhanced tumor growth. 
  • Sustained release of nerve growth factor from biodegradable polymer microspheres. 
  • Sympatho-adrenal development in perinatally addicted rats. 
  • Synaptic organization and acetylcholine sensitivity of multiply innervated autonomic ganglion cells. 
  • Synergistic effects of oPL and insulin on glycogen metabolism in fetal rat hepatocytes. 
  • Taste-specific neuronal ensembles in the gustatory cortex of awake rats. 
  • Temperature immutability of adenyl cyclase-coupled beta adrenergic receptors. 
  • The cubic ternary complex receptor-occupancy model. III. resurrecting efficacy. 
  • The influence of changes in blood volume on angina pectoris. A study of the effect of phlebotomy. 
  • The influence of lipofectin on the in vitro stimulation of murine spleen cells by bacterial DNA and plasmid DNA vectors. 
  • The influence of removing extracellular Ca2+ in the desensitization responses to capsaicin, zingerone and olvanil in rat trigeminal ganglion neurons. 
  • The value of basal serum follicle stimulating hormone, luteinizing hormone and oestradiol concentrations following pituitary down-regulation in predicting ovarian response to stimulation with highly purified follicle stimulating hormone. 
  • Tissue specificity of renin promoter activity and regulation in mice. 
  • Transfection of ovarian cancer cells with tumor necrosis factor-alpha (TNF-alpha) antisense mRNA abolishes the proliferative response to interleukin-1 (IL-1) but not TNF-alpha. 
  • Tumor necrosis factor-alpha induces increased hydrogen peroxide production and Fc receptor expression, but not increased Ia antigen expression by peritoneal macrophages. 
  • Upake of plasma lipids by extrahepatic tissues of vitamin A fed rats. 
  • Urea tolerance as a molecular adaptation of elasmobranch hemoglobins. 
  • Use of nitroprusside to increase tissue temperature during local hyperthermia in normal and tumor-bearing dogs. 
  • Vasoactive intestinal peptide stimulates protein phosphorylation in a colonic epithelial cell line. 
  • [The combined effect of 2 first-line anti-arrhythmia drugs on the conduction velocity of myocardial stimulation]. 
  • beta-Adrenergic action on wild-type and KPQ mutant human cardiac Na+ channels: shift in gating but no change in Ca2+:Na+ selectivity. 
  • p-Chlorophenylalanine-induced enhancement of the effects of morphine on the adrenal medulla. 
  • β-Arrestin mediates oxytocin receptor signaling, which regulates uterine contractility and cellular migration. 
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  Keywords of People

  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Bradford, Daniel William, Professor of Psychiatry and Behavioral Sciences, Psychiatry, Child & Family Mental Health & Community Psychiatry
  • Schwartz-Bloom, Rochelle D., Professor Emeritus of Pharmacology & Cancer Biology, Duke Science & Society