Streptococcus pyogenes

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  Subject Areas on Research

  • A combination of independent transcriptional regulators shapes bacterial virulence gene expression during infection. 
  • A direct link between carbohydrate utilization and virulence in the major human pathogen group A Streptococcus. 
  • A light-inducible CRISPR-Cas9 system for control of endogenous gene activation. 
  • Activity of faropenem against middle ear fluid pathogens from children with acute otitis media in Costa Rica and Israel. 
  • Adherence of streptococcus pyogenes, Escherichia coli, and Pseudomonas aeruginosa to fibronectin-coated and uncoated epithelial cells. 
  • Annihilating host defense. 
  • Azithromycin chemoprophylaxis. 
  • Cas9 loosens its grip on off-target sites. 
  • Characterization of Staphylococcus aureus Cas9: a smaller Cas9 for all-in-one adeno-associated virus delivery and paired nickase applications. 
  • Comparative evaluation of medium and atmosphere of incubation for isolation of Streptococcus pyogenes. 
  • Crystal structure of Streptococcus pyogenes sortase A: implications for sortase mechanism. 
  • Degradation of 14C-labeled streptococcal cell walls by egg white lysozyme and lysosomal enzymes. 
  • Delayed myonecrosis in a leukemic patient with invasive group A streptococcal disease. 
  • Diagnosis of streptococcal pharyngitis by detection of Streptococcus pyogenes in posterior pharyngeal versus oral cavity specimens. 
  • Distinct single amino acid replacements in the control of virulence regulator protein differentially impact streptococcal pathogenesis. 
  • Effect of atmosphere and duration of incubation on primary isolation of group A streptococci from throat cultures. 
  • Etiology of pediatric fever in western Kenya: a case-control study of falciparum malaria, respiratory viruses, and streptococcal pharyngitis. 
  • Evaluation of penicillin and hyperbaric oxygen in the treatment of streptococcal myositis. 
  • Exploring the basis of peptide-carbohydrate crossreactivity: evidence for discrimination by peptides between closely related anti-carbohydrate antibodies. 
  • Hyperendemic Streptococcus pyogenes infection despite prophylaxis with penicillin G benzathine. 
  • Hypervirulent group A Streptococcus emergence in an acaspular background is associated with marked remodeling of the bacterial cell surface. 
  • Identification of a chimeric emm gene and novel emm pattern in currently circulating strains of emm4 Group A Streptococcus. 
  • In vitro activity of BAY 12-8039, a new fluoroquinolone, against species representative of respiratory tract pathogens. 
  • In vitro activity of telithromycin against macrolide-susceptible and macrolide-resistant pharyngeal isolates of group A streptococci in the United States. 
  • Increasing the specificity of CRISPR systems with engineered RNA secondary structures. 
  • Index of suspicion. 
  • Interpreting a single antistreptolysin O test: a comparison of the "upper limit of normal" and likelihood ratio methods. 
  • Is parental report of upper respiratory infection at the onset of obsessive-compulsive disorder suggestive of pediatric autoimmune neuropsychiatric disorder associated with streptococcal infection? 
  • Modulation of lymphocyte functions by group A streptococcal membrane. 
  • Molecular characterization of group A Streptococcus maltodextrin catabolism and its role in pharyngitis. 
  • Multicentre surveillance of the prevalence and molecular epidemiology of macrolide resistance among pharyngeal isolates of group A streptococci in the USA. 
  • National Department of Defense surveillance data for antibiotic resistance and emm gene types of clinical group A streptococcal isolates from eight basic training military sites. 
  • Necrotizing fasciitis and myositis caused by group A streptococci. Epidemiology, diagnosis, and treatment of "flesh-eating bacteria". 
  • Niche-specific contribution to streptococcal virulence of a MalR-regulated carbohydrate binding protein. 
  • Obsessive-compulsive disorder in children and adolescents: a review of the past 10 years. 
  • Oral erythromycin prophylaxis against Streptococcus pyogenes infection in penicillin-allergic military recruits: a randomized clinical trial. 
  • Performance of rapid streptococcal antigen testing varies by personnel. 
  • Pericolic abscess due to Streptococcus pyogenes: report of a case that clinically mimicked acute cholecystitis. 
  • Periocular necrotizing fasciitis in an infant. 
  • Pharyngeal colonization prevalence rates for Streptococcus pyogenes and Streptococcus pneumoniae in a respiratory chemoprophylaxis intervention study using azithromycin. 
  • Pooled analysis of the phase 3 REVIVE trials: randomised, double-blind studies to evaluate the safety and efficacy of iclaprim versus vancomycin for treatment of acute bacterial skin and skin-structure infections. 
  • Predicting bacteremic pneumonia in HIV-1-infected patients consulting the ED. 
  • Prevention of invasive group A streptococcal disease among household contacts of case patients and among postpartum and postsurgical patients: recommendations from the Centers for Disease Control and Prevention. 
  • Respiratory diseases among U.S. military personnel: countering emerging threats. 
  • Rheumatic Heart Disease in the Twenty-First Century. 
  • Serologic evidence of respiratory and rickettsial infections among Somali refugees. 
  • Strep throat: guidelines for diagnosis and treatment. 
  • Streptococcal pharyngitis leading to corneal ulceration. 
  • Streptococcal toxic shock syndrome: a physician tells the story of her survival. 
  • Successful management of orbital cellulitis and temporary visual loss after blepharoplasty. 
  • Suppression of hepatitis B virus DNA accumulation in chronically infected cells using a bacterial CRISPR/Cas RNA-guided DNA endonuclease. 
  • Toxic strep syndrome.