Subarachnoid Hemorrhage

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  Subject Areas on Research

  • A Double-Blind, Randomized, Placebo-Controlled Trial of Soluble Epoxide Hydrolase Inhibition in Patients with Aneurysmal Subarachnoid Hemorrhage. 
  • A Narrative Review of Cardiovascular Abnormalities After Spontaneous Intracerebral Hemorrhage. 
  • A novel apoE-derived therapeutic reduces vasospasm and improves outcome in a murine model of subarachnoid hemorrhage. 
  • A risk score for in-hospital death in patients admitted with ischemic or hemorrhagic stroke. 
  • ACR Appropriateness Criteria® Cerebrovascular Diseases-Aneurysm, Vascular Malformation, and Subarachnoid Hemorrhage. 
  • Accuracy of transcranial Doppler ultrasonography and single-photon emission computed tomography in the diagnosis of angiographically demonstrated cerebral vasospasm. 
  • Acute hypertension after stroke: the scientific basis for treatment decisions. 
  • Acute subdural hematomas secondary to aneurysmal subarachnoid hemorrhage confer poor prognosis: a national perspective. 
  • An apoE-derived mimic peptide, COG1410, alleviates early brain injury via reducing apoptosis and neuroinflammation in a mouse model of subarachnoid hemorrhage. 
  • An observational pilot study of CSF diversion in subarachnoid haemorrhage. 
  • Aneurysmal Subarachnoid Hemorrhage in Patients with Coronavirus Disease 2019 (COVID-19): A Case Series. 
  • Aneurysmal subarachnoid hemorrhage in patients under 35-years-old: a single-center experience. 
  • Angiographic Features of Intracranial Aneurysms in Ecuador. 
  • Apolipoprotein E Exerts a Whole-Brain Protective Property by Promoting M1? Microglia Quiescence After Experimental Subarachnoid Hemorrhage in Mice. 
  • Apolipoprotein E mimetic peptide CN-105 improves outcome in a murine model of SAH. 
  • Aspirin and Intracranial Aneurysms. 
  • Assessment of circulating blood volume with fluid administration targeting euvolemia or hypervolemia. 
  • Association Between Hospital Volumes and Clinical Outcomes for Patients With Nontraumatic Subarachnoid Hemorrhage. 
  • Attenuation of cerebral vasospasm after subarachnoid hemorrhage in mice overexpressing extracellular superoxide dismutase. 
  • Biospecimens and Molecular and Cellular Biomarkers in Aneurysmal Subarachnoid Hemorrhage Studies: Common Data Elements and Standard Reporting Recommendations. 
  • CT evaluation of subarachnoid hemorrhage: a practical review for the radiologist interpreting emergency room studies. 
  • CT perfusion-derived mean transit time predicts early mortality and delayed vasospasm after experimental subarachnoid hemorrhage. 
  • Cardiac Dysfunction After Neurologic Injury: What Do We Know and Where Are We Going? 
  • Cerebral aneurysms: mechanisms of injury and critical care interventions. 
  • Cerebral blood flow dynamics and head-of-bed changes in the setting of subarachnoid hemorrhage. 
  • Cerebral blood flow velocity response to magnesium sulfate in patients after subarachnoid hemorrhage. 
  • Cerebral hemodynamic and metabolic changes caused by brain retraction after aneurysmal subarachnoid hemorrhage. 
  • Cerebral mycotic aneurysm in a child with Down's syndrome: a unique association. 
  • Cerebral oxygen metabolism after aneurysmal subarachnoid hemorrhage. 
  • Cerebrospinal fluid atrial natriuretic factor in intracranial disease. 
  • Cervical sympathetic block to reverse delayed ischemic neurological deficits after aneurysmal subarachnoid hemorrhage. 
  • Changing outcome from aneurysmal subarachnoid hemorrhage: another step closer. 
  • Characteristics of Unruptured Compared to Ruptured Intracranial Aneurysms: A Multicenter Case-Control Study. 
  • Characteristics of nontraumatic subarachnoid hemorrhage in the United States in 2003. 
  • Characteristics, performance measures, and in-hospital outcomes of the first one million stroke and transient ischemic attack admissions in get with the guidelines-stroke. 
  • Clinical Policy: Critical Issues in the Evaluation and Management of Adult Patients Presenting to the Emergency Department With Acute Headache. 
  • Clinical and Imaging Features of Contrast-Induced Neurotoxicity After Neurointerventional Surgery. 
  • Clinical prediction models for aneurysmal subarachnoid hemorrhage: a systematic review. 
  • Clinicopathological conference of the Medical University of South Carolina. "Convulsion in a 55 year old man with protracted chronic osteomyelitis". 
  • Comments on "sensitivity of noncontrast cranial computed tomography for the emergency department diagnosis of subarachnoid hemorrhage". 
  • Common Data Element for Unruptured Intracranial Aneurysm and Subarachnoid Hemorrhage: Recommendations from Assessments and Clinical Examination Workgroup/Subcommittee. 
  • Common Data Elements for Radiological Imaging of Patients with Subarachnoid Hemorrhage: Proposal of a Multidisciplinary Research Group. 
  • Common Data Elements for Subarachnoid Hemorrhage and Unruptured Intracranial Aneurysms: Recommendations from the Working Group on Subject Characteristics. 
  • Common Data Elements for Unruptured Intracranial Aneurysm and Subarachnoid Hemorrhage Clinical Research: Recommendations from the Working Group on Long-Term Therapies. 
  • Common Data Elements for Unruptured Intracranial Aneurysms and Aneurysmal Subarachnoid Hemorrhage: Recommendations from the Working Group on Hospital Course and Acute Therapies-Proposal of a Multidisciplinary Research Group. 
  • Common Data Elements for Unruptured Intracranial Aneurysms and Subarachnoid Hemorrhage Clinical Research: A National Institute for Neurological Disorders and Stroke and National Library of Medicine Project. 
  • Comparison of techniques for ventriculoperitoneal shunting in 523 patients with subarachnoid hemorrhage. 
  • Continuous and intermittent CSF diversion after subarachnoid hemorrhage: a pilot study. 
  • Continuous cerebral spinal fluid drainage associated with complications in patients admitted with subarachnoid hemorrhage. 
  • Continuous monitoring of cerebrovascular reactivity through pulse transit time and intracranial pressure. 
  • Correlation of serum brain natriuretic peptide with hyponatremia and delayed ischemic neurological deficits after subarachnoid hemorrhage. 
  • Costs of vasospasm in patients with aneurysmal subarachnoid hemorrhage. 
  • Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society's Multidisciplinary Consensus Conference. 
  • Current practices of triple-H prophylaxis and therapy in patients with subarachnoid hemorrhage. 
  • Decompressive craniectomy in aneurysmal subarachnoid hemorrhage: Who and when? - A systematic review and meta-analysis. 
  • Development and validation of outcome prediction models for aneurysmal subarachnoid haemorrhage: the SAHIT multinational cohort study. 
  • Differential Sex Response to Aspirin in Decreasing Aneurysm Rupture in Humans and Mice. 
  • Diffuse cerebral venous air embolism following subarachnoid hemorrhage. Case illustration. 
  • Dissociation between vasospasm and functional improvement in a murine model of subarachnoid hemorrhage. 
  • Distinguishing Characteristics of Headache in Nontraumatic Subarachnoid Hemorrhage. 
  • Diverse Use of the WEB Device: A Technical Note on WEB Stenting and WEB Coiling of Complex Aneurysms. 
  • Dual antiplatelet therapy in aneurysmal subarachnoid hemorrhage: association with reduced risk of clinical vasospasm and delayed cerebral ischemia. 
  • Dual antiplatelet therapy. 
  • Dynamic CT perfusion imaging in subarachnoid hemorrhage-related vasospasm. 
  • Dysregulation of oxygen hemodynamic responses to synaptic train stimulation in a rat hippocampal model of subarachnoid hemorrhage. 
  • Effect of High-Dose Simvastatin on Cerebral Blood Flow and Static Autoregulation in Subarachnoid Hemorrhage. 
  • Effect of normal saline bolus on cerebral blood flow in regions with low baseline flow in patients with vasospasm following subarachnoid hemorrhage. 
  • Effects of patient-level noise abatement orders on sound levels experienced by critically ill subarachnoid hemorrhage patients: an observational study. 
  • Efficacy of multiple intraarterial papaverine infusions for improvement in cerebral circulation time in patients with recurrent cerebral vasospasm. 
  • Endovascular Treatment of Ruptured Vertebrobasilar Dissecting Aneurysms Using Flow Diversion Embolization Devices: Single-Institution Experience. 
  • Endovascular management of cerebral vasospasm following aneurysm rupture: outcomes and predictors in 116 patients. 
  • Endovascular treatment of cerebral vasospasm. 
  • Endovascular treatment of distal intracranial aneurysms with Onyx 18/34. 
  • Estrogen protects against intracranial aneurysm rupture in ovariectomized mice. 
  • External Ventricular Drain and Hemorrhage in Aneurysmal Subarachnoid Hemorrhage Patients on Dual Antiplatelet Therapy: A Retrospective Cohort Study. 
  • Galbraith Award: simvastatin attenuates experimental cerebral vasospasm and ameliorates serum markers of neuronal and endothelial injury in patients after subarachnoid hemorrhage: a dose-response effect dependent on endothelial nitric oxide synthase. 
  • Global Survey of Outcomes of Neurocritical Care Patients: Analysis of the PRINCE Study Part 2. 
  • Global, regional, and national burden of stroke and its risk factors, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. 
  • Haptoglobin genotype and aneurysmal subarachnoid hemorrhage: Individual patient data analysis. 
  • Healthcare Economics of Hydrocephalus After Aneurysmal Subarachnoid Hemorrhage in the United States. 
  • Hemodynamic management of subarachnoid hemorrhage. 
  • Hemorrhage associated with ventriculoperitoneal shunt placement in aneurysmal subarachnoid hemorrhage patients on a regimen of dual antiplatelet therapy: a retrospective analysis. 
  • Hospital case volume is associated with mortality in patients hospitalized with subarachnoid hemorrhage. 
  • Hospitalization and case-fatality rates for subarachnoid hemorrhage in Canada from 1982 through 1991. The Canadian Collaborative Study Group of Stroke Hospitalizations. 
  • Imaging evaluation of the patient with worst headache of life--it's not all subarachnoid hemorrhage. 
  • Impact of ruptured cerebral aneurysm coiling and clipping on the incidence of cerebral vasospasm and clinical outcome. 
  • In Reply: External Ventricular Drain and Hemorrhage in Aneurysmal Subarachnoid Hemorrhage Patients on Dual Antiplatelet Therapy: A Retrospective Cohort Study. 
  • In vitro and numerical simulation of blood removal from cerebrospinal fluid: comparison of lumbar drain to Neurapheresis therapy. 
  • In-hospital outcomes of aneurysmal subarachnoid hemorrhage associated with cocaine use in the USA. 
  • Incidence of cerebral ischemic events after discontinuation of clopidogrel in patients with intracranial aneurysms treated with stent-assisted techniques. 
  • Influence of stroke subtype on quality of care in the Get With The Guidelines-Stroke Program. 
  • Infundibular Dilations and Subarachnoid Hemorrhage: to Treat or Not to Treat? 
  • Inhibition of Blood-Brain Barrier Disruption by an Apolipoprotein E-Mimetic Peptide Ameliorates Early Brain Injury in Experimental Subarachnoid Hemorrhage. 
  • Inpatient costs of specific cerebrovascular events at five academic medical centers. 
  • Intraventricular extension of an aneurysmal subarachnoid hemorrhage is an independent predictor of a worse functional outcome. 
  • Letter by Hasan et al Regarding Article, "Aspirin and Risk of Subarachnoid Hemorrhage: Systematic Review and Meta-Analysis". 
  • Leukocytosis as an independent risk factor for cerebral vasospasm following aneurysmal subarachnoid hemorrhage. 
  • Levetiracetam is neuroprotective in murine models of closed head injury and subarachnoid hemorrhage. 
  • Long-Term Cognitive Deficits After Subarachnoid Hemorrhage in Rats. 
  • Long-term cognitive dysfunction following experimental subarachnoid hemorrhage: new perspectives. 
  • Loss of Consciousness at Onset of Aneurysmal Subarachnoid Hemorrhage is Associated with Functional Outcomes in Good-Grade Patients. 
  • MRI SPACE sequence confirmation of occluded MCA M2 dissection stump masquerading as a ruptured MCA aneurysm. 
  • Magnesium neuroprotection is limited in humans with acute brain injury. 
  • Management of post-subarachnoid hemorrhage vasospasm. 
  • Management of unruptured incidentally found intracranial saccular aneurysms. 
  • Mechanical Thrombectomy of Acutely Occluded Flow Diverters. 
  • Medical complications of aneurysmal subarachnoid hemorrhage: a report of the multicenter, cooperative aneurysm study. Participants of the Multicenter Cooperative Aneurysm Study. 
  • Melatonin and risk of mortality in subjects with aneurysmal subarachnoid hemorrhage. 
  • Meta-analysis of intracranial hemorrhage in acute coronary syndromes: incidence, predictors, and clinical outcomes. 
  • Mouse model of subarachnoid hemorrhage associated cerebral vasospasm: methodological analysis. 
  • Multiplexed protein profiling after aneurysmal subarachnoid hemorrhage: characterization of differential expression patterns in cerebral vasospasm. 
  • Navigating the ventricles: Novel insights into the pathogenesis of hydrocephalus. 
  • Neurogenic Stunned Myocardium Following Acute Subarachnoid Hemorrhage: Pathophysiology and Practical Considerations. 
  • Neurogenic pulmonary edema during intracranial endovascular therapy. 
  • Neuroprotection in subarachnoid hemorrhage. 
  • Neuroprotective effect of curcumin in an experimental rat model of subarachnoid hemorrhage. 
  • Neuroprotective efficacy from a lipophilic redox-modulating Mn(III) N-Hexylpyridylporphyrin, MnTnHex-2-PyP: rodent models of ischemic stroke and subarachnoid hemorrhage. 
  • Novel Dual Lumen Catheter and Filtration Device for Removal of Subarachnoid hemorrhage: First Case Report. 
  • Novel Treatment of Cerebral Vasospasm Using Solitaire Stent Retriever-Assisted Angioplasty: Case Series. 
  • Pathophysiology of Delayed Cerebral Ischemia After Subarachnoid Hemorrhage: A Review. 
  • Perioperative fever and outcome in surgical patients with aneurysmal subarachnoid hemorrhage. 
  • Perioperative management of aneurysmal subarachnoid hemorrhage: Part 1. Operative management. 
  • Perioperative management of aneurysmal subarachnoid hemorrhage: Part 2. Postoperative management. 
  • Persistent perioperative hyperglycemia as an independent predictor of poor outcome after aneurysmal subarachnoid hemorrhage. 
  • Pharmacologically augmented S-nitrosylated hemoglobin improves recovery from murine subarachnoid hemorrhage. 
  • Phase 1/2a Trial of ISPASM. 
  • Physiological and histopathological responses following closed rotational head injury depend on direction of head motion. 
  • Possible role for vascular cell proliferation in cerebral vasospasm after subarachnoid hemorrhage. 
  • Potential implications of Apolipoprotein E in early brain injury after experimental subarachnoid hemorrhage: Involvement in the modulation of blood-brain barrier integrity. 
  • Potential role of aspirin in the prevention of aneurysmal subarachnoid hemorrhage. 
  • Predictors of Delayed Cerebral Ischemia in Patients with Aneurysmal Subarachnoid Hemorrhage with Asymptomatic Angiographic Vasospasm on Admission. 
  • Preliminary results in the analysis of the immune response after aneurysmal subarachnoid hemorrhage. 
  • Prevention of chronic cerebral vasospasm in dogs with milrinone. 
  • Prioritization and Timing of Outcomes and Endpoints After Aneurysmal Subarachnoid Hemorrhage in Clinical Trials and Observational Studies: Proposal of a Multidisciplinary Research Group. 
  • Processed electroencephalogram during donation after cardiac death. 
  • Prognostic value of premorbid hypertension and neurological status in aneurysmal subarachnoid hemorrhage: pooled analyses of individual patient data in the SAHIT repository. 
  • Prospective Trial of Cerebrospinal Fluid Filtration After Aneurysmal Subarachnoid Hemorrhage via Lumbar Catheter (PILLAR). 
  • Proteomic biomarker discovery in cerebrospinal fluid for cerebral vasospasm following subarachnoid hemorrhage. 
  • Quantitative Assessment of Ventriculostomy-Related Hemorrhage: A Volume-Based Classification System to Predict New Neurological Symptoms. 
  • Quantitative Susceptibility Mapping as a Possible Tool to Radiographically Diagnose Sentinel Headache Associated with Intracranial Aneurysm: Case Report. 
  • Randomized pilot trial of intensive management of blood pressure or volume expansion in subarachnoid hemorrhage (IMPROVES). 
  • Reversal of warfarin associated coagulopathy with 4-factor prothrombin complex concentrate in traumatic brain injury and intracranial hemorrhage. 
  • Review of medical prevention of vasospasm after aneurysmal subarachnoid hemorrhage: a problem of neurointensive care. 
  • Risk of cerebral vasopasm after subarachnoid hemorrhage reduced by statin therapy: A multivariate analysis of an institutional experience. 
  • Risk of hemorrhagic complication associated with ventriculoperitoneal shunt placement in aneurysmal subarachnoid hemorrhage patients on dual antiplatelet therapy. 
  • Risk of intracranial aneurysms in families with subarachnoid hemorrhage. 
  • Risk of ventriculostomy-related hemorrhage in patients with acutely ruptured aneurysms treated using stent-assisted coiling. 
  • Role of vascular mitogens in subarachnoid hemorrhage-associated cerebral vasculopathy. 
  • SAHIT Investigators--on the outcome of some subarachnoid hemorrhage clinical trials. 
  • Safety and Efficacy of a 600-mg Loading Dose of Clopidogrel 24 Hours Before Pipeline Embolization Device Treatment. 
  • Secular Increases in Spontaneous Subarachnoid Hemorrhage during Pregnancy: A Nationwide Sample Analysis. 
  • Serum von Willebrand factor, matrix metalloproteinase-9, and vascular endothelial growth factor levels predict the onset of cerebral vasospasm after aneurysmal subarachnoid hemorrhage. 
  • Sex differences in delayed cerebral ischemia after subarachnoid hemorrhage. 
  • Short- and long-term opioid use in survivors of subarachnoid hemorrhage. 
  • Simvastatin increases endothelial nitric oxide synthase and ameliorates cerebral vasospasm resulting from subarachnoid hemorrhage. 
  • Simvastatin reduces vasospasm after aneurysmal subarachnoid hemorrhage: results of a pilot randomized clinical trial. 
  • Simvastatin treatment duration and cognitive preservation in experimental subarachnoid hemorrhage. 
  • Single-Dose Intraventricular Nimodipine Microparticles Versus Oral Nimodipine for Aneurysmal Subarachnoid Hemorrhage. 
  • Smooth Muscle Peroxisome Proliferator-Activated Receptor γ Plays a Critical Role in Formation and Rupture of Cerebral Aneurysms in Mice In Vivo. 
  • Spontaneous delayed migration/shortening of the pipeline embolization device: report of 5 cases. 
  • Spontaneous vertebral dissection: clinical, conventional angiographic, CT, and MR findings. 
  • Stent-assisted coiling of wide-necked aneurysms in the setting of acute subarachnoid hemorrhage: experience in 65 patients. 
  • Stress cardiomyopathy with an "inverse" takotsubo pattern in a patient with acute aneurysmal subarachnoid hemorrhage. 
  • Subarachnoid Hemorrhage International Trialists data repository (SAHIT). 
  • Subarachnoid hemorrhage from intracranial dissecting aneurysm. 
  • Subarachnoid hemorrhage trials. 
  • Synthes Award for Resident Research in Spinal Cord & Spinal Column Injury: Statins for the treatment of neurological injury: a role beyond cholesterol lowering. 
  • Systematic review of the prevention of delayed ischemic neurological deficits with hypertension, hypervolemia, and hemodilution therapy following subarachnoid hemorrhage. 
  • Temporal bone fracture. 
  • Temporal changes in glutamate, glutamate transporters, basilar arteries wall thickness, and neuronal variability in an experimental rat model of subarachnoid hemorrhage. 
  • The Chicken or the Egg: Hypertension Secondary to Intraoperative Subarachnoid Hemorrhage. 
  • The Safety and Efficacy of Continuous Tirofiban as a Monoantiplatelet Therapy in the Management of Ruptured Aneurysms Treated Using Stent-Assisted Coiling or Flow Diversion and Requiring Ventricular Drainage. 
  • The Subarachnoid Hemorrhage International Trialists (SAHIT) Repository: advancing clinical research in subarachnoid hemorrhage. 
  • The association between fluid balance and outcomes after subarachnoid hemorrhage. 
  • The new standing guideline committee policy of the American Stroke Association Stroke Council. 
  • The relationship of blunt head trauma, subarachnoid hemorrhage, and rupture of pre-existing intracranial saccular aneurysms. 
  • The risk of intracranial aneurysms in families with subarachnoid hemorrhage. 
  • The significance of intraocular hemorrhages due to subarachnoid hemorrhage. 
  • The use of S100B as a biomarker in subarachnoid hemorrhage: clarity in its promise and limits. 
  • The use of alternatives to clopidogrel in flow-diversion treatment with the Pipeline embolization device. 
  • The utility of cone beam volume CT in the evaluation of thrombosed intracranial aneurysms in subarachnoid hemorrhage. 
  • The utility of cone beam volume CT in the evaluation of thrombosed intracranial aneurysms in subarachnoid hemorrhage. 
  • The value of CT angiography and transcranial doppler sonography in triaging suspected cerebral vasospasm in SAH prior to endovascular therapy. 
  • Therapeutic implications of estrogen for cerebral vasospasm and delayed cerebral ischemia induced by aneurysmal subarachnoid hemorrhage. 
  • Thrombotic, infectious, and procedural complications of the jugular bulb catheter in the intensive care unit. 
  • Timing of symptomatic vasospasm in aneurysmal subarachnoid hemorrhage: the effect of treatment modality and clinical implications. 
  • Tirofiban Protocol Protects Against Delayed Cerebral Ischemia: A Case-Series Study. 
  • Transcranial Doppler Ultrasound During Critical Illness in Children: Survey of Practices in Pediatric Neurocritical Care Centers. 
  • Treatment and diagnosis of cerebral aneurysms in the post-International Subarachnoid Aneurysm Trial (ISAT) era: trends and outcomes. 
  • Treatment of cerebral vasospasm after subarachnoid hemorrhage--a review. 
  • Treatment outcome of aneurysmal subarachnoid hemorrhage in patients aged 70 years and older. 
  • Use of the peak troponin value to differentiate myocardial infarction from reversible neurogenic left ventricular dysfunction associated with aneurysmal subarachnoid hemorrhage. 
  • Utility of CT angiography in the identification and characterization of supraclinoid internal carotid artery blister aneurysms. 
  • Utility of levetiracetam in patients with subarachnoid hemorrhage. 
  • Validity of exchangeable solute balance as a measure of blood volume in neurologically injured adults. 
  • Which H is the most important in triple-H therapy for cerebral vasospasm? 
  • [Prevention of vasospasm secondary to subarachnoid hemorrhage caused by ruptured aneurysm: management]. 
  • pH-sensitive NMDA inhibitors improve outcome in a murine model of SAH. 
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  Keywords of People

  • Curtis, Lesley H., Professor in Population Health Sciences, Medicine, General Internal Medicine
  • James, Michael Lucas, Associate Professor of Anesthesiology, Anesthesiology
  • Laskowitz, Daniel Todd, Professor of Neurology, Duke Science & Society
  • Reed, Shelby Derene, Professor in Population Health Sciences, Duke Science & Society
  • Sheng, Huaxin, Associate Professor in Anesthesiology, Anesthesiology