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Subject Areas on Research
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6-Hydroxydopamine injections into the nigrostriatal pathway attenuate striatal malonate and 3-nitropropionic acid lesions.
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A Neural Circuit for Gut-Induced Reward.
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Abrogation of α-synuclein-mediated dopaminergic neurodegeneration in LRRK2-deficient rats.
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Activation of substantia nigra neurons: role in the propagation of seizures in kindled rats.
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Activation of substantia nigra pars reticulata neurons: role in the initiation and behavioral expression of kindled seizures.
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Activity of neurons in monkey globus pallidus during oculomotor behavior compared with that in substantia nigra pars reticulata.
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Acute and chronic nicotinic interactions with dopamine systems and working memory performance.
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Anatomy of disturbed sleep in pallido-ponto-nigral degeneration.
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Androgen decreases dopamine neurone survival in rat midbrain.
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Anticonvulsant action of intranigral gamma-vinyl-GABA: role of nonadrenergic neurotransmission.
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Augmented methamphetamine-induced overflow of striatal dopamine 1 day after GDNF administration.
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Autophagy protects against aminochrome-induced cell death in substantia nigra-derived cell line.
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Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice.
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Bidirectional modulation of substantia nigra activity by motivational state.
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Biochemical and behavioral evaluation of pergolide as a dopamine agonist in the rat brain.
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CHEMICAL STIMULATION OF RED NUCLEUS, SUBSTANTIA NIGRA, AND BASIS PEDUNCULI IN ALERT CATS.
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Central acoustic tract in an echolocating bat: an extralemniscal auditory pathway to the thalamus.
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Changes in dynorphin, enkephalin and cholecystokinin content of hippocampus and substantia nigra after amygdala kindling.
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Characterization of the axon initial segment of mice substantia nigra dopaminergic neurons.
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Chronic cocaine administration increases CNS tyrosine hydroxylase enzyme activity and mRNA levels and tryptophan hydroxylase enzyme activity levels.
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Chronic lithium administration has no effect on haloperidol-induced supersensitivity of pre- and postsynaptic dopamine receptors in rat brain.
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Cloning, pharmacological characterization, and chromosome assignment of the human dopamine transporter.
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Colocalization of excitatory and inhibitory neurotransmitter markers in striatal projection neurons in the rat.
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Combined treatment with acupuncture reduces effective dose and alleviates adverse effect of L-dopa by normalizing Parkinson's disease-induced neurochemical imbalance.
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Creatine and cyclocreatine attenuate MPTP neurotoxicity.
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Differential LRRK2 expression in the cortex, striatum, and substantia nigra in transgenic and nontransgenic rodents.
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Differential expression of the B'beta regulatory subunit of protein phosphatase 2A modulates tyrosine hydroxylase phosphorylation and catecholamine synthesis.
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Differential response of ventral midbrain and striatal progenitor cells to lesions of the nigrostriatal dopaminergic projection.
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Does dopamine contribute to striatal damage caused by impaired mitochondrial function?
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Dopamine and α-synuclein dysfunction in Smad3 null mice.
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Dopamine receptors status after unilateral nigral 6-OHDA lesion. Autoradiographic and in situ hybridization study in the rat brain.
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Dopamine: burning the candle at both ends.
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Dopaminergic neurodegeneration induced by Parkinson's disease-linked G2019S LRRK2 is dependent on kinase and GTPase activity.
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Dual control of dopamine synthesis and release by presynaptic and postsynaptic dopamine D2 receptors.
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Effects of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP)-induced hemiparkinsonism on the kinematics of a two-dimensional,multijoint arm movement in the rhesus monkey.
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Effects of intranigral application of clinically-effective anticonvulsants on electroshock-induced seizures.
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Evidence implicating alpha-2 adrenergic receptors in the anticonvulsant action of intranigral muscimol.
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Evidence implicating substantia nigra in regulation of kindled seizure threshold.
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Evidence that Substantia Nigra is crucial to neural network of kindled seizures.
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Exploring the role of the substantia nigra pars reticulata in eye movements.
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Expression profiling of substantia nigra in Parkinson disease, progressive supranuclear palsy, and frontotemporal dementia with parkinsonism.
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Extraocular muscle dystonia due to acquired (non-Wilsonian) hepatocerebral degeneration.
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Fast serotonin voltammetry as a versatile tool for mapping dynamic tissue architecture: I. Responses at carbon fibers describe local tissue physiology.
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Frequency-Specific Optogenetic Deep Brain Stimulation of Subthalamic Nucleus Improves Parkinsonian Motor Behaviors.
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Functional association of the parkin gene promoter with idiopathic Parkinson's disease.
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GDNF protection against 6-OHDA-induced reductions in potassium-evoked overflow of striatal dopamine.
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Gene delivery of neurturin to putamen and substantia nigra in Parkinson disease: A double-blind, randomized, controlled trial.
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Genetic regulation of alpha-synuclein mRNA expression in various human brain tissues.
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Genomic convergence to identify candidate genes for Parkinson disease: SAGE analysis of the substantia nigra.
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Genomic convergence: identifying candidate genes for Parkinson's disease by combining serial analysis of gene expression and genetic linkage.
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Identification and quantification of dolichol and dolichoic acid in neuromelanin from substantia nigra of the human brain.
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Identification of a novel gene linked to parkin via a bi-directional promoter.
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Induction of c-fos mRNA by kindled seizures: complex relationship with neuronal burst firing.
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Interactions of nigrostriate synaptic transmission, iontophoretic O-methylated phenethylamines, dopamine, apomorphine and acetylcholine.
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Intranigral administration of D2 dopamine receptor antisense oligodeoxynucleotides establishes a role for nigrostriatal D2 autoreceptors in the motor actions of cocaine.
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Intranigral dynorphin-1-13 suppresses kindled seizures by a naloxone-insensitive mechanism.
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Kindling model of epilepsy.
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Kindling: an animal model of complex partial epilepsy.
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LC/MS analysis of cardiolipins in substantia nigra and plasma of rotenone-treated rats: Implication for mitochondrial dysfunction in Parkinson's disease.
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Lesioning of the striatum reverses motor asymmetry in the 6-hydroxydopamine rodent model of parkinsonism.
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Leucine-rich Repeat Kinase 2 (LRRK2) Pharmacological Inhibition Abates α-Synuclein Gene-induced Neurodegeneration.
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Levels of alpha-synuclein mRNA in sporadic Parkinson disease patients.
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Luminopsins integrate opto- and chemogenetics by using physical and biological light sources for opsin activation.
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MR microscopy at 7.0 T: effects of brain iron.
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MRI of brain iron.
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Mechanisms of action selection and timing in substantia nigra neurons.
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Microinjection of a benzodiazepine into substantia nigra elevates kindled seizure threshold.
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Mitochondrial DNA damage: molecular marker of vulnerable nigral neurons in Parkinson's disease.
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Morphometry of the human substantia nigra in ageing and Parkinson's disease.
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Neurobiochemical changes in tardive dyskinesia.
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Neuroinflammation and α-synuclein dysfunction potentiate each other, driving chronic progression of neurodegeneration in a mouse model of Parkinson's disease.
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Neurological disturbances, nigrostriate synapses, and iontophoretic dopamine and apomorphine after haloperidol.
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Neurotensin-induced dopamine release in vivo and in vitro from substantia nigra and nucleus caudate.
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Nitrated alpha-synuclein immunity accelerates degeneration of nigral dopaminergic neurons.
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Oestrogen receptors enhance dopamine neurone survival in rat midbrain.
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Operant self-stimulation of dopamine neurons in the substantia nigra.
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Overexpression of VMAT-2 and DT-diaphorase protects substantia nigra-derived cells against aminochrome neurotoxicity.
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Parkinson plus syndrome: diagnosis using high field MR imaging of brain iron.
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Quantitative 1H magnetic resonance spectroscopic imaging determines therapeutic immunization efficacy in an animal model of Parkinson's disease.
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Regulatory T cells attenuate Th17 cell-mediated nigrostriatal dopaminergic neurodegeneration in a model of Parkinson's disease.
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Relationships between the nigrotectal pathway and the cells of origin of the predorsal bundle.
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Relative contributions of local cell and passing fiber activation and silencing to changes in thalamic fidelity during deep brain stimulation and lesioning: a computational modeling study.
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Resting state networks distinguish human ventral tegmental area from substantia nigra.
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Role of the substantia nigra in the kindling model of limbic epilepsy.
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Safety/feasibility of targeting the substantia nigra with AAV2-neurturin in Parkinson patients.
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Single-cell redox imaging demonstrates a distinctive response of dopaminergic neurons to oxidative insults.
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Stimulation of substantia nigra pars reticulata enhances dentate granule cell excitability.
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Striatonigral control of movement velocity in mice.
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Substantia nigra activity level predicts trial-to-trial adjustments in cognitive control.
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Synapsins differentially control dopamine and serotonin release.
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Synthesis and dopamine agonist properties of (+-)-trans-3,4,4a,10b-tetrahydro-4-propyl-2H,5H-[1]benzopyrano [4,3-b]-1,4-oxazin-9-ol and its enantiomers.
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Targeted deletion of GD3 synthase protects against MPTP-induced neurodegeneration.
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The G2019S LRRK2 mutation increases myeloid cell chemotactic responses and enhances LRRK2 binding to actin-regulatory proteins.
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The effects of chronic bromocriptine treatment on behaviour and dopamine receptor binding in the rat striatum.
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The nigral projection to predorsal bundle cells in the superior colliculus of the rat.
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The nigrotectal projection in the cat: an electron microscope autoradiographic study.
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The role of substantia nigra in the development of kindling: pharmacologic and lesion studies.
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The role of the substantia nigra in posture control.
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The sources of the nigrotectal pathway.
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The surface oxidation potential of human neuromelanin reveals a spherical architecture with a pheomelanin core and a eumelanin surface.
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Therapeutic immunization protects dopaminergic neurons in a mouse model of Parkinson's disease.
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Tyrosine hydroxylase mRNA in the neurons of the tuberoinfundibular region and zona incerta examined after gonadal steroid hormone treatment.
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Voltammetric evidence for discrete serotonin circuits, linked to specific reuptake domains, in the mouse medial prefrontal cortex.
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Working memory performance and cholinergic effects in the ventral tegmental area and substantia nigra.
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α-Synuclein fibril-induced inclusion spread in rats and mice correlates with dopaminergic Neurodegeneration.
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Keywords of People