Sympathetic Nervous System

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  Subject Areas on Research

  • Abnormalities of cardiac sympathetic function in pacing-induced heart failure as assessed by [123I]metaiodobenzylguanidine scintigraphy. 
  • Accelerated development of rat sympathetic neurotransmission caused by neonatal triiodothyronine administration. 
  • Accentuated vagal antagonism of beta-adrenergic effects on ventricular repolarization. Evidence of weaker antagonism in hostile type A men. 
  • Adolescent nicotine exposure produces immediate and long-term changes in CNS noradrenergic and dopaminergic function. 
  • Aerobic exercise reduces levels of cardiovascular and sympathoadrenal responses to mental stress in subjects without prior evidence of myocardial ischemia. 
  • Alterations in the development of catecholamine turnover induced by perinatal methadone: differences in central vs. peripheral sympathetic nervous systems. 
  • An in vitro neurite-promoting antigen functions in axonal regeneration in vivo. 
  • An intrinsic adrenergic system in mammalian heart. 
  • Anatomy and physiology of the cornea. 
  • Apparent treatment-resistant hypertension and chronic kidney disease: another cardiovascular-renal syndrome? 
  • Association of Resting Heart Rate With Blood Pressure and Incident Hypertension Over 30 Years in Black and White Adults: The CARDIA Study. 
  • Autonomic activation links CNS oxygen toxicity to acute cardiogenic pulmonary injury. 
  • Baroreceptor Modulation of the Cardiovascular System, Pain, Consciousness, and Cognition. 
  • Baroreflex activation in conscious rats modulates the joint inflammatory response via sympathetic function. 
  • Behavioral effects of acute hexamethonium in rats chronically intoxicated with nicotine. 
  • Beta adrenergic control of macromolecule synthesis in neonatal rat heart, kidney and lung: relationship to sympathetic neuronal development. 
  • Beyond pharmacological treatment: an insight into therapies that target specific aspects of heart failure pathophysiology. 
  • Beyond the Anatomy of Renal Nerves: Functional Diversity of Renal Nerves. 
  • Biobehavioral basis of coronary-prone behavior in middle-aged men. Part I: Evidence for chronic SNS activation in Type As. 
  • Blood pressure dipping: ethnicity, sleep quality, and sympathetic nervous system activity. 
  • Brain control of blood glucose levels: implications for the pathogenesis of type 2 diabetes. 
  • CNS inflammation and bone marrow neuropathy in type 1 diabetes. 
  • Can behavioural factors produce a sustained elevation of blood pressure? Some observations and a hypothesis. 
  • Cardiovascular hemodynamics during stress in premenopausal versus postmenopausal women. 
  • Carotid body resection for sympathetic modulation in systolic heart failure: results from first-in-man study. 
  • Carotid sinus nerve electrical stimulation in conscious rats attenuates systemic inflammation via chemoreceptor activation. 
  • Central catecholaminergic lesions in the developing rat: effects of cardiac noradrenaline levels, turnover and release. 
  • Central glucagon like peptide-1 delays solid gastric emptying via central CRF and peripheral sympathetic pathway in rats. 
  • Central sympathetic blockade ameliorates brain death-induced cardiotoxicity and associated changes in myocardial gene expression. 
  • Cerebral vasodilation and vasoconstriction associated with acute anxiety. 
  • Characterization of the hyperpolarization-activated chloride current in dissociated rat sympathetic neurons. 
  • Comments on Point:Counterpoint: The dominant contributor to systemic hypertension: Chronic activation of the sympathetic nervous system vs. Activation of the intrarenal renin-angiotensin system. Activated intrarenal renin-angiotensin system is correlated with high blood pressure in humans. 
  • Connexin 43 Mediates White Adipose Tissue Beiging by Facilitating the Propagation of Sympathetic Neuronal Signals. 
  • Contributions of neuroendocrine and local autocrine-paracrine mechanisms to the pathophysiology and pharmacology of congestive heart failure. 
  • Delta 9 -tetrahydrocannabinol and ethanol: differential effects on sympathetic activity in differing environmental setting. 
  • Depression and anxiety symptoms are related to increased 24-hour urinary norepinephrine excretion among healthy middle-aged women. 
  • Development of central control of norepinephrine turnover and release in the rat heart: responses to tyramine, 2-deoxyglucose and hydralazine. 
  • Development of prejunctional alpha 2 adrenergic receptor mediated feedback control of the pressor response to sympathetic nerve stimulation in hypertensive and normotensive rats. 
  • Developmental effects of alpha-fluoromethylhistidine, an irreversible inhibitor of histidine decarboxylase, on growth and on levels and turnover of catecholamines. 
  • Developmental neurotoxicity targeting hepatic and cardiac sympathetic innervation: effects of organophosphates are distinct from those of glucocorticoids. 
  • Developmental shift from local to central control of norepinephrine release in the cardiac-sympathetic axis: effects of cocaine and related drugs. 
  • Differential sympathetic neural control of oxygenation in resting and exercising human skeletal muscle. 
  • Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons. 
  • Do sympathetic neurons coordinate cellular development in the heart and kidney? Effects of neonatal central and peripheral catecholaminergic lesions on cardiac and renal nucleic acids and proteins. 
  • Effect of autonomic blockade on the hemodynamic findings in acute cardiac tamponade. 
  • Effect of brief myocardial ischemia on sympathetic coronary vasoconstriction. 
  • Effects of chronic chlorisondamine administration on the sympatho-adrenal axis. 
  • Effects of electroacupuncture on gastric motility and heart rate variability in conscious rats. 
  • Effects of perinatal exposure to methadone on development of neurotransmission: biochemical bases for behavioral alterations. 
  • Effects of postnatal reserpine administration on sympatho-adrenal development in the rat. 
  • Effects of vasomotor- and mediator-induced hypotension on bronchomotor tone in swine. 
  • Electrocardiographic characteristics of potential organ donors and associations with cardiac allograft use. 
  • Evidence for p53-mediated modulation of neuronal viability. 
  • Exendin-4 increases blood glucose levels acutely in rats by activation of the sympathetic nervous system. 
  • Fetal dexamethasone exposure interferes with establishment of cardiac noradrenergic innervation and sympathetic activity. 
  • Fetal nicotinic overload, blunted sympathetic responsivity, and obesity. 
  • Force-frequency relations in the failing rabbit heart and responses to adrenergic stimulation. 
  • Formation and maintenance of synaptic connections in autonomic ganglia. 
  • Gata3 loss leads to embryonic lethality due to noradrenaline deficiency of the sympathetic nervous system. 
  • Glucocorticoids and the development of neuronal function: effects of prenatal dexamethasone exposure on central noradrenergic activity. 
  • Hemodynamic and sympathetic nervous system responses to stress during the menstrual cycle. 
  • Hepatic fibrogenesis requires sympathetic neurotransmitters. 
  • Homeostatic regulation of airway smooth muscle tone by catecholamine secretion in swine. 
  • Hostility is related to blunted beta-adrenergic receptor responsiveness among middle-aged women. 
  • How does lower education get inside the body to raise blood pressure? What can we do to prevent this? 
  • Hypotensive effect of clonidine is not mediated by enhanced baroreflex gain in rats. 
  • Impaired development of central and peripheral catecholamine neurotransmitter systems in preweanling rats treated with alpha-difluoromethylornithine, a specific irreversible inhibitor of ornithine decarboxylase. 
  • Increased expression of galanin in the rat superior cervical ganglion after pre- and postganglionic nerve lesions. 
  • Inhibition of spinal p38 MAPK prevents articular neutrophil infiltration in experimental arthritis via sympathetic activation. 
  • Inhibition of sympathetic pathways restores postoperative ileus in the upper and lower gastrointestinal tract. 
  • Interaction of signals influencing renin release. 
  • Intracranial and extracranial blood flow during acute anxiety. 
  • Involvement of the sympathetic nervous system in the urinary bladder internal sphincter and in penile erection in the anesthetized cat. 
  • Learning new tricks from old dogs: beta-adrenergic receptors teach new lessons on firing up adipose tissue metabolism. 
  • Lower central nervous system serotonergic function and risk of cardiovascular disease: where are we, what's next? 
  • Magnitude of abdominal incision affects the duration of postoperative ileus in rats. 
  • Maturation of sympathetic neurotransmission in the rat heart--III. Developmental changes in reserpine inhibition of norepinephrine uptake into isolated synaptic vesicles. 
  • Maturation of sympathetic neurotransmission in the rat heart. IV. Effects guanethidine-induced sympathectomy on neonatal development of synaptic vesicles, synaptic terminal function and heart growth. 
  • Maturation of sympathetic neurotransmission in the rat heart. IX. Development of transsynaptic regulation of cardiac adrenergic sensitivity. 
  • Maturation of sympathetic neurotransmission in the rat heart. V. Development of baroreceptor control of sympathetic tone. 
  • Maturation of sympathetic neurotransmission in the rat heart. VI. The effect of neonatal central catecholaminergic lesions. 
  • Maturation of sympathetic neurotransmission in the rat heart. VII. Suppression of sympathetic responses by dexamethasone. 
  • Maturation of sympathetic neurotransmission in the rat heart. VIII. Slowed development of noradrenergic synapses resulting from hypothyroidism. 
  • Mechanisms of reflex bladder activation by pudendal afferents. 
  • Mechanistic Insights into Sympathetic Neuronal Regeneration: Multitracer Molecular Imaging of Catecholamine Handling After Cardiac Transplantation. 
  • Metaiodobenzylguanidine imaging in diabetes mellitus: assessment of cardiac sympathetic denervation and its relation to autonomic dysfunction and silent myocardial ischemia. 
  • Modulation of experimental arthritis by vagal sensory and central brain stimulation. 
  • Modulation of the BP response to diet by genes in the renin-angiotensin system and the adrenergic nervous system. 
  • Myocardial G protein-coupled receptor kinases: implications for heart failure therapy. 
  • Neonatal central catecholaminergic lesions with intracisternal 6-hydroxydopamine: effects on development of presynaptic and postsynaptic components of peripheral sympathetic pathways and on the ornithine decarboxylase/polyamine system in heart, lung and kidney. 
  • Neonatal methylmercury poisoning in the rat: effects on development of peripheral sympathetic nervous system. Neuronal participation in methylmercury-induced cardiac and renal overgrowth. 
  • Neonatal nutritional deprivation or enhancement: the cardiac-sympathetic axis and its role in cardiac growth and stress responses. 
  • Neural factors in the development of renal function: effect of neonatal central catecholaminergic lesions with 6-hydroxydopamine. 
  • Neural input and the development of adrenergic intracellular signaling: neonatal denervation evokes neither receptor upregulation nor persistent supersensitivity of adenylate cyclase. 
  • Neural substrate for atrial fibrillation: implications for targeted parasympathetic blockade in the posterior left atrium. 
  • Neural units in the superior cervical ganglion of the guinea-pig. 
  • Neurobiology, cellular and molecular biology, and psychosomatic medicine. 
  • Neurohormonal control of exocrine pancreatic secretion. 
  • Neurohumoral mechanisms in heart failure: role in pathogenesis, therapy, and drug tolerance. 
  • Neuronal control of cardiac and hepatic macromolecule synthesis in the neonatal rat: effects of sympathectomy. 
  • Nighttime blood pressure dipping: the role of the sympathetic nervous system. 
  • Non-canonical Ret signaling augments p75-mediated cell death in developing sympathetic neurons. 
  • Norepinephrine induces hepatic fibrogenesis in leptin deficient ob/ob mice. 
  • Norepinephrine regulates hepatic innate immune system in leptin-deficient mice with nonalcoholic steatohepatitis. 
  • Obligatory role of thyroid hormones in development of peripheral sympathetic and central nervous system catecholaminergic neurons: effects of propylthiouracil-induced hypothyroidism on transmitter levels, turnover and release. 
  • Ornithine decarboxylase as a tool in developmental neurobiology. 
  • Ornithine decarboxylase in developing rat heart and brain: role of sympathetic development for responses to autonomic stimulants and the effects of reserpine on maturation. 
  • Orthostatic intolerance and gastrointestinal motility in adolescents with nausea and abdominal pain. 
  • Oxidative stress and nerve function after cardiopulmonary bypass in patients with diabetes. 
  • Pathophysiology of experimental renovascular hypertension. 
  • Persistent innervation of mammalian sympathetic neurones by native and foreign fibres. 
  • Pharmacological blockade of a β(2)AR-β-arrestin-1 signaling cascade prevents the accumulation of DNA damage in a behavioral stress model. 
  • Polycystic kidney disease strikes a nerve. 
  • Possible difference in the sympathetic activation on extreme dippers with or without exaggerated morning surge. 
  • Precocious development of sympatho-adrenal function in rats whose mothers received methadone. 
  • Premature development of cardiac sympathetic neurotransmission in the fetal alcohol syndrome. 
  • Prenatal exposure to nicotine via maternal infusions: effects on development of catecholamine systems. 
  • Presynaptic and postsynaptic contributions to ontogeny of sympathetic control of heart rate in the pre-weanling rat. 
  • Race and gender comparisons: II. Predictions of work blood pressure from laboratory baseline and cardiovascular reactivity measures. 
  • Regional cardiac sympathetic innervation early and late after transmyocardial laser revascularization. 
  • Response to cardiac sympathetic activation in transgenic mice overexpressing beta 2-adrenergic receptor. 
  • Response to role of the carotid body in obesity-related sympathoactivation. 
  • Restraint stress delays solid gastric emptying via a central CRF and peripheral sympathetic neuron in rats. 
  • Role of leptin in fat regulation. 
  • Role of receptor mechanisms in the adaptive response to habitual exercise. 
  • Role of stress in the etiology and treatment of diabetes mellitus. 
  • Role of sympathetic neurons in biochemical and functional development of the kidney: neonatal sympathectomy with 6-hydroxydopamine. 
  • Role of sympathetic neurons in development of beta-adrenergic control of ornithine decarboxylase activity in peripheral tissues: effects of neonatal 6-hydroxydopamine treatment. 
  • Sensory pudendal nerve stimulation increases bladder capacity through sympathetic mechanisms in cyclophosphamide-induced cystitis rats. 
  • Serum dopamine-beta-hydroxylase (DBH) activity and blood pressure response of rat strains to shock-induced fighting. 
  • Stress and autonomic nervous system in type II diabetes. A hypothesis. 
  • Stress in the fetus and newborn. 
  • Sympathectomy in the treatment of angina and arrhythmias. 
  • Sympathetic nervous system inhibition increases hepatic progenitors and reduces liver injury. 
  • Sympathetic nervous system regulation of liver repair. 
  • Sympathetic response to intracranial NGF infusion in the absence of afferent input: axonal sprouting without neurotransmitter production. 
  • Sympathoadrenergic mechanisms in reduced hemodynamic stress responses after exercise. 
  • Sympathohippocampal neurons are inside the blood--brain barrier. 
  • Tactile-kinesthetic stimulation effects on sympathetic and adrenocortical function in preterm infants. 
  • Target size regulates calibre and myelination of sympathetic axons. 
  • The Effects of Tryptophan Enhancement and Depletion on Plasma Catecholamine Levels in Healthy Individuals. 
  • The beta-adrenergic receptors and the control of adipose tissue metabolism and thermogenesis. 
  • The cardiac-sympathetic axis as a teratological model. 
  • The carotid body as a therapeutic target for the treatment of sympathetically mediated diseases. 
  • The effect of pentobarbital anesthesia on the autonomic nervous system control of heart rate during baroreceptor activation. 
  • The effects of peripheral chemosympathectomy and adrenalectomy upon blood pressure responses of the rat to footshock under varying conditions: evidence for behavioral effects on patterning of sympathetic nervous system responses. 
  • The epidemiology, pathophysiology, and management of psychosocial risk factors in cardiac practice: the emerging field of behavioral cardiology. 
  • The impact of aging on adrenergic receptor function: clinical and biochemical aspects. 
  • The renin-angiotensin-aldosterone system: a specific target for hypertension management. 
  • The role of behavior in diabetes care. 
  • The β-adrenoceptor agonist isoproterenol rescues acetaminophen-injured livers through increasing progenitor numbers by Wnt in mice. 
  • Thresholds for thermal damage to normal tissues: an update. 
  • Treatment of HF in an Era of Multiple Therapies: Statement From the HF Collaboratory. 
  • Trophic control of lung development by sympathetic neurons: effects of neonatal sympathectomy with 6-hydroxydopamine. 
  • Type A behavior pattern and coronary atherosclerosis. 
  • Unaltered cerebral blood flow during hypoglycemic activation of the sympathochromaffin system in humans. 
  • Uptake and retention kinetics of para-fluorine-18-fluorobenzylguanidine in isolated rat heart. 
  • Vascular Type 1A Angiotensin II Receptors Control BP by Regulating Renal Blood Flow and Urinary Sodium Excretion. 
  • Vascular α1-Adrenergic Receptor Responsiveness in Masked Hypertension. 
  • Verapamil prolongs atrial fibrillation by evoking an intense sympathetic neurohumoral effect. 
  • Young children are intrinsically motivated to see others helped. 
  • beta(3)-adrenoceptor deficiency blocks nitric oxide-dependent inhibition of myocardial contractility. 
  • α7-cholinergic receptor mediates vagal induction of splenic norepinephrine. 
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  Keywords of People

  • Jordt, Sven Eric, Associate Professor in Anesthesiology, Pharmacology & Cancer Biology