Synaptosomes
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Subject Areas on Research
- A selective imidazobenzodiazepine antagonist of ethanol in the rat.
- Acute stress enhances the activity of the GABA receptor-gated chloride ion channel in brain.
- Age-related differences in neurosteroid potentiation of muscimol-stimulated 36Cl(-) flux following chronic ethanol treatment.
- Alcohols stimulate gamma-aminobutyric acid receptor-mediated chloride uptake in brain vesicles: correlation with intoxication potency.
- Aspartate release from rat hippocampal synaptosomes.
- Barbiturate and picrotoxin-sensitive chloride efflux in rat cerebral cortical synaptoneurosomes.
- Beta-adrenergic receptor binding: synaptic localization in rat brain.
- Bidirectional modulation of GABA-gated chloride channels by divalent cations: inhibition by Ca2+ and enhancement by Mg2+.
- Calcium-dependent cytosolic phospholipase A2 activation is implicated in neuroinflammation and oxidative stress associated with ApoE4.
- Calcium-dependent cytosolic phospholipase A2 activation is implicated in neuroinflammation and oxidative stress associated with ApoE4.
- Calcium/calmodulin inhibits direct binding of spectrin to synaptosomal membranes.
- Catecholamine synthesis, storage and release in adrenal medulla and whole brain during acute and chronic methadone administration.
- Cellular regulation of the benzodiazepine/GABA receptor: arachidonic acid, calcium, and cerebral ischemia.
- Characterization of GABAA receptor-mediated 36chloride uptake in rat brain synaptoneurosomes.
- Chlorpyrifos releases norepinephrine from adult and neonatal rat brain synaptosomes.
- Concomitant development of [3H]-dopamine and [3H]-5-hydroxytryptamine uptake systems in rat brain regions.
- Demonstration of GABA/barbiturate-receptor-mediated chloride transport in rat brain synaptoneurosomes: a functional assay of GABA receptor-effector coupling.
- Development of alpha-noradrenergic and Dopaminergic receptor systems depends on maturation of their presynaptic nerve terminals in the rat brain.
- Development of polyamine and biogenic amine systems in brains and hearts of neonatal rats given dexamethasone: role of biochemical alterations in cellular maturation for producing deficits in ontogeny of neurotransmitter levels, uptake, storage and turnover.
- Differential seizure sensitivities to picrotoxinin in two inbred strains of mice (DBA/2J and BALB/c ByJ): parallel changes in GABA receptor-mediated chloride flux and receptor binding.
- Dual role of the exocyst in AMPA receptor targeting and insertion into the postsynaptic membrane.
- Effect of cocaine and cocaine congeners on veratridine-induced depolarization in mouse cerebrocortical synaptoneurosomes.
- Effects of maternal ethanol ingestion on amine uptake into synaptosomes of fetal and neonatal rat brain.
- Effects of neonatal hypoxia on brain development in the rat: immediate and long-term biochemical alterations in discrete regions.
- Ethanol stimulates gamma-aminobutyric acid receptor-mediated chloride transport in rat brain synaptoneurosomes.
- Exposure to methylmercury in utero: effects on biochemical development of catecholamine neurotransmitter systems.
- Factors modulating the sensitivity of the GABA receptor-gated chloride ion channel.
- Functionally relevant gamma-aminobutyric acidA receptors: equivalence between receptor affinity (Kd) and potency (EC50)?
- GABA receptor-mediated chloride transport in a "cell-free" membrane preparation from brain.
- GBR12909 stimulates hypothalamo-pituitary-adrenal activity by inhibition of uptake at hypothalamic dopamine neurons.
- Glutamate and dynorphin release from a subcellular fraction enriched in hippocampal mossy fiber synaptosomes.
- Impairment of synaptic vesicle clustering and of synaptic transmission, and increased seizure propensity, in synapsin I-deficient mice.
- Indirect and direct inhibition of dopamine beta-hydroxylase by amphetamine in storage vesicles and synaptosomes.
- Inhibition of GABA-gated chloride channel function by arachidonic acid.
- Inhibition of GABA-gated chloride channels in brain by the arachidonic acid metabolite, thromboxane A2.
- Measurement of chloride movement in neuronal preparations.
- Methadone inhibits serotonin and norephinephrine uptake into rat brain synaptosomes and synaptic vesicles in vitro but not in vivo.
- Neonatal methylmercury poisoning in the rat: effects on development of central catecholamine neurotransmitter systems.
- Ontogeny of (--)-[3H]norepinephrine uptake properties of synaptic storage vesicles of rat brain.
- Perforant path lesion depletes glutamate content of fascia dentata synaptosomes.
- Perinatal methadone addiction affects brain synaptic development of biogenic amine systems in the rat.
- Postsynaptic response to stimulation of the Schaffer collaterals with properties similar to those of synaptosomal aspartate release.
- Reduced aspartate release from rat hippocampal synaptosomes loaded with Clostridial toxin light chain by electroporation: evidence for an exocytotic mechanism.
- Regulation of gamma-aminobutyric acid/barbiturate receptor-gated chloride ion flux in brain vesicles by phospholipase A2: possible role of oxygen radicals.
- Regulation of hippocampal sympathetic ingrowth: role of afferent input.
- Regulatory changes in presynaptic cholinergic function assessed in rapid autopsy material from patients with Alzheimer disease: implications for etiology and therapy.
- Release of glutamate and aspartate from CA1 synaptosomes: selective modulation of aspartate release by ionotropic glutamate receptor ligands.
- Serotonin transporter expression in rat brain regions and blood platelets: aging and glucocorticoid effects.
- Sex differences in neurochemical effects of dopaminergic drugs in rat striatum.
- Sodium-dependent proline and glutamate uptake by hippocampal synaptosomes during postnatal development.
- Sodium-dependent proline uptake in the rat hippocampal formation: association with ipsilateral-commissural projections of CA3 pyramidal cells.
- Subcellular distribution of transmitter-related enzyme activities in discrete areas of the rat dentate gyrus.
- Synaptic development in brains of rats exposed perinatally to ethanol.
- Transformation of mu-opioid receptor agonists into biologically potent mu-opioid receptor antagonists.
- Undernutrition and overnutrition in the neonatal rat: long-term effects on noradrenergic pathways in brain regions.
- Uptake of (-) 3H-norepinephrine by storage vesicles prepared from whole rat brain: properties of the uptake system and its inhibition by drugs.
- Uptake of serotonin into rat platelets and synaptosomes: comparative structure-activity relationships, energetics and evaluation of the effects of acute and chronic nortriptyline administration.
- cAMP analogs inhibit gamma-aminobutyric acid-gated chloride flux and activate protein kinase A in brain synaptoneurosomes.
- cAMP and forskolin decrease gamma-aminobutyric acid-gated chloride flux in rat brain synaptoneurosomes.
- gamma-Aminobutyric acid (GABA)- and barbiturate-mediated 36Cl- uptake in rat brain synaptoneurosomes: evidence for rapid desensitization of the GABA receptor-coupled chloride ion channel.
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Keywords of People
- Bennett, Vann, George Barth Geller Distinguished Professor of Molecular Biology, Duke Cancer Institute