Synovial Fluid
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Subject Areas on Research
- 3D osteoarthritic changes in TMJ condylar morphology correlates with specific systemic and local biomarkers of disease.
- A comparative analysis of bone and cartilage metabolism in two strains of guinea-pig with varying degrees of naturally occurring osteoarthritis.
- Acute dislocation of the patella. A correlative pathoanatomic study.
- Alpha defensin-1 attenuates surgically induced osteoarthritis in association with promoting M1 to M2 macrophage polarization.
- Amino Acid Profile of Synovial Fluid Following Intra-articular Ankle Fracture.
- Anti-inflammatory effects of naproxen sodium on human osteoarthritis synovial fluid immune cells.
- Antigen-induced arthritis. Decreased proteoglycan content and inhibition of proteoglycan synthesis in articular cartilage.
- Articular ankle fracture results in increased synovitis, synovial macrophage infiltration, and synovial fluid concentrations of inflammatory cytokines and chemokines.
- Ascorbic acid accumulates in cartilage in vivo.
- Ascorbic acid increases the severity of spontaneous knee osteoarthritis in a guinea pig model.
- Aspiration of the asymptomatic metatarsophalangeal joint in gout patients and hyperuricemic controls.
- Aspiration of the knee joint before revision arthroplasty.
- Assessment of the utility of biomarkers of osteoarthritis in the guinea pig.
- Association of chemokine expression in anterior cruciate ligament deficient knee with patient characteristics: Implications for post-traumatic osteoarthritis.
- Both systemic and local lipopolysaccharide (LPS) burden are associated with knee OA severity and inflammation.
- Changes in serum and synovial fluid biomarkers after acute injury (NCT00332254).
- Colchicine effectiveness in symptom and inflammation modification in knee osteoarthritis (COLKOA): study protocol for a randomized controlled trial.
- Colchicine lack of effectiveness in symptom and inflammation modification in knee osteoarthritis (COLKOA): a randomized controlled trial.
- Collagen, collagenase and clinicians.
- Commercially Available Polymerase Chain Reaction Has Minimal Utility in the Diagnosis of Periprosthetic Joint Infection.
- Comparison of synovial fluid cartilage marker concentrations and chondral damage assessed arthroscopically in acute knee injury.
- Conditional Macrophage Depletion Increases Inflammation and Does Not Inhibit the Development of Osteoarthritis in Obese Macrophage Fas-Induced Apoptosis-Transgenic Mice.
- Cytokine-regulated expression of activated leukocyte cell adhesion molecule (CD166) on monocyte-lineage cells and in rheumatoid arthritis synovium.
- DEK in the synovium of patients with juvenile idiopathic arthritis: characterization of DEK antibodies and posttranslational modification of the DEK autoantigen.
- Diagnosis of Prosthetic Joint Infection.
- Diagnosis of crystal induced arthritis by dark field microscopy.
- Differential activation of human neutrophil cytosolic phospholipase A2 and secretory phospholipase A2 during priming by 1,2-diacyl- and 1-O-alkyl-2-acylglycerols.
- Dysregulated Inflammatory Response Related to Cartilage Degradation after ACL Injury.
- Editorial: Insulin Resistance: Releasing the Brakes on Synovial Inflammation and Osteoarthritis?
- Effects of intraarticular IL1-Ra for acute anterior cruciate ligament knee injury: a randomized controlled pilot trial (NCT00332254).
- Enrichment of malondialdehyde-acetaldehyde antibody in the rheumatoid arthritis joint.
- Evidence for polymorphonuclear-leucocyte-derived proteinases in arthritic cartilage.
- Extracellular Vesicles as Biological Indicators and Potential Sources of Autologous Therapeutics in Osteoarthritis.
- Fibronectin in the tendon-synovial complex: quantitation in vivo and in vitro by ELISA and relative mRNA levels by polymerase chain reaction and northern blot.
- Functional and prognostic relevance of the -173 polymorphism of the macrophage migration inhibitory factor gene in systemic-onset juvenile idiopathic arthritis.
- Hyaluronan molecular weight distribution is associated with the risk of knee osteoarthritis progression.
- Immune cell profiles in synovial fluid after anterior cruciate ligament and meniscus injuries.
- Immune cell profiling in the joint following human and murine articular fracture.
- In vivo cartilage strain increases following medial meniscal tear and correlates with synovial fluid matrix metalloproteinase activity.
- Inflammatory Cytokines and Matrix Metalloproteinases in the Synovial Fluid After Intra-articular Ankle Fracture.
- Inflammatory Microenvironment Persists After Bone Healing in Intra-articular Ankle Fractures.
- Inflammatory biomarkers in osteoarthritis.
- Inflammatory cytokines and cellular metabolites as synovial fluid biomarkers of posttraumatic ankle arthritis.
- Inflammatory cytokines and matrix metalloproteinases in the synovial fluid after intra-articular elbow fracture.
- Infrapatellar fat pad abnormalities are associated with a higher inflammatory synovial fluid cytokine profile in young adults following ACL tear.
- Interaction of lubricin with type II collagen surfaces: adsorption, friction, and normal forces.
- Intra-Articular Synovial Fluid With Hematoma After Ankle Fracture Promotes Cartilage Damage In Vitro Partially Attenuated by Anti-Inflammatory Agents.
- Intra-articular delivery of purified mesenchymal stem cells from C57BL/6 or MRL/MpJ superhealer mice prevents posttraumatic arthritis.
- Joint Fluid Proteome after Anterior Cruciate Ligament Rupture Reflects an Acute Posttraumatic Inflammatory and Chondrodegenerative State.
- Kingella kingae expresses type IV pili that mediate adherence to respiratory epithelial and synovial cells.
- Leukemia-associated arthritis: identification of leukemic cells in synovial fluid using monoclonal and polyclonal antibodies.
- Lipid profile of human synovial fluid following intra-articular ankle fracture.
- Longitudinal characterization of synovial fluid biomarkers in the canine meniscectomy model of osteoarthritis.
- MRI of joint fluid in the normal and ischemic hip.
- Matrix metalloproteinase activity and prostaglandin E2 are elevated in the synovial fluid of meniscus tear patients.
- Measurement of an adhesion molecule as an indicator of inflammatory disease activity. Up-regulation of the receptor for hyaluronate (CD44) in rheumatoid arthritis.
- Measurement of synovial fluid volume using urea.
- Mechanism of hypochlorite-mediated inactivation of proteinase inhibition by alpha 2-macroglobulin.
- Medical management of acute gout.
- Microparticles stimulate the synthesis of prostaglandin E(2) via induction of cyclooxygenase 2 and microsomal prostaglandin E synthase 1.
- Molecular abnormalities of human plasminogen isolated from synovial fluid of rheumatoid arthritis patients.
- Monoclonal antibodies to human cartilage oligomeric matrix protein: epitope mapping and characterization of sandwich ELISA.
- Mycoplasma hominis septic arthritis: two case reports and review.
- Novel synovial fluid recovery method allows for quantification of a marker of arthritis in mice.
- PILAR is a novel modulator of human T-cell expansion.
- Post-translational aging of proteins in osteoarthritic cartilage and synovial fluid as measured by isomerized aspartate.
- Premature cell senescence and T cell receptor-independent activation of CD8+ T cells in juvenile idiopathic arthritis.
- Proceedings from the 2018 International Consensus Meeting on Orthopedic Infections: evaluation of periprosthetic shoulder infection.
- Radiographic severity of knee osteoarthritis is conditional on interleukin 1 receptor antagonist gene variations.
- Relationship between T1rho magnetic resonance imaging, synovial fluid biomarkers, and the biochemical and biomechanical properties of cartilage.
- Septic arthritis caused by Propionibacterium acnes.
- Soluble macrophage biomarkers indicate inflammatory phenotypes in patients with knee osteoarthritis.
- Soluble recombinant neutral endopeptidase (CD10) as a potential antiinflammatory agent.
- Sustained intra-articular delivery of IL-1RA from a thermally-responsive elastin-like polypeptide as a therapy for post-traumatic arthritis.
- Synergistic Roles of Macrophages and Neutrophils in Osteoarthritis Progression.
- Synovial Fluid Profile at the Time of Anterior Cruciate Ligament Reconstruction and Its Association With Cartilage Matrix Composition 3 Years After Surgery.
- Synovial and systemic pharmacokinetics (PK) of triamcinolone acetonide (TA) following intra-articular (IA) injection of an extended-release microsphere-based formulation (FX006) or standard crystalline suspension in patients with knee osteoarthritis (OA).
- Synovial fluid biomarker levels predict articular cartilage damage following complete medial meniscectomy in the canine knee.
- Synovial fluid biomarkers associated with osteoarthritis severity reflect macrophage and neutrophil related inflammation.
- Synovial fluid concentrations and relative potency of interleukin-1 alpha and beta in cartilage and meniscus degradation.
- Synovial fluid metabolites in osteonecrosis.
- Synovial fluid pro-inflammatory profile differs according to the characteristics of knee pain.
- TSG-6 - a double-edged sword for osteoarthritis (OA).
- TSG-6 activity as a novel biomarker of progression in knee osteoarthritis.
- The Inflamma-type: a patient phenotype characterized by a dysregulated inflammatory response after lower extremity articular fracture.
- The effects of adipokines on cartilage and meniscus catabolism.
- The role of leukocyte adhesion molecules in cellular interactions: implications for the pathogenesis of inflammatory synovitis.
- Time-Dependent Effects on Synovial Fluid Composition During the Acute Phase of Human Intra-articular Ankle Fracture.
- Traditional Laboratory Markers Hold Low Diagnostic Utility for Immunosuppressed Patients With Periprosthetic Joint Infections.
- Urea as a passive transport marker for arthritis biomarker studies.
- Use of a multiple-enzyme/multiple-reagent assay system to quantify activity levels in samples containing mixtures of matrix metalloproteinases.
- Whole-body bone scintigraphy provides a measure of the total-body burden of osteoarthritis for the purpose of systemic biomarker validation.
- Xanthine oxidase injurious response in acute joint injury.
- alpha(2)-Macroglobulin from rheumatoid arthritis synovial fluid: functional analysis defines a role for oxidation in inflammation.
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Keywords of People
- Olson, Steven Arthur, Goldner Jones Distinguished Professor of Orthopaedic Surgery, Orthopaedic Surgery