Synovial Membrane

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  Subject Areas on Research

  • Acute joint pathology and synovial inflammation is associated with increased intra-articular fracture severity in the mouse knee. 
  • Antigen-induced arthritis. Decreased proteoglycan content and inhibition of proteoglycan synthesis in articular cartilage. 
  • Arthritis syndromes associated with human T cell lymphotropic virus type I infection. 
  • Articular ankle fracture results in increased synovitis, synovial macrophage infiltration, and synovial fluid concentrations of inflammatory cytokines and chemokines. 
  • Association of the CCR5 gene with juvenile idiopathic arthritis. 
  • B cells in rheumatoid synovitis. 
  • CCN1 Regulates Chondrocyte Maturation and Cartilage Development. 
  • CXCL10 is upregulated in synovium and cartilage following articular fracture. 
  • CXCR3 and CCR5 ligands in rheumatoid arthritis synovium. 
  • Calcification of entheses associated with X-linked hypophosphatemic osteomalacia. 
  • Characterization of the plasminogen receptors of normal and rheumatoid arthritis human synovial fibroblasts. 
  • Chemokines have diverse abilities to form solid phase gradients. 
  • Circulating immune complexes contain citrullinated fibrinogen in rheumatoid arthritis. 
  • Collagenolytic activity of synovium in rheumatoid arthritis. 
  • Contracture and transient receptor potential channel upregulation in the anterior glenohumeral joint capsule of patients with end-stage osteoarthritis. 
  • Cytologic findings in tenosynovial giant cell tumors investigated by fine-needle aspiration cytology. 
  • Differential effects of interleukin-1 alpha, tumor necrosis factor-alpha, indomethacin, hydrocortisone, and macrophage co-culture on the proliferation of human fibroblasts and peritoneal mesothelial cells. 
  • Editorial: Insulin Resistance: Releasing the Brakes on Synovial Inflammation and Osteoarthritis? 
  • Elbow MR imaging findings in patients with synovial fringe syndrome. 
  • Engraftment of human synovium into severe combined immune deficient mice. Migration of human peripheral blood T cells to engrafted human synovium and to mouse lymph nodes. 
  • Evaluation of indium-111 chloride as a radiopharmaceutical for joint imaging in a rabbit model of arthritis. 
  • Expression of CD44 variants in human inflammatory synovitis. 
  • Expression of E-selectin messenger RNA and protein in rheumatoid arthritis. 
  • Extravascular fibrin formation and dissolution in synovial tissue of patients with osteoarthritis and rheumatoid arthritis. 
  • Genetic and cellular evidence of decreased inflammation associated with reduced incidence of posttraumatic arthritis in MRL/MpJ mice. 
  • Genetic control of inflammatory arthritis and glomerulonephritis in congenic lpr mice and their F1 hybrids. 
  • Genetic control of inflammatory arthritis in congenic lpr mice. 
  • Global metabolic profiling of human osteoarthritic synovium. 
  • Glycoprotein 96 perpetuates the persistent inflammation of rheumatoid arthritis. 
  • Heat shock protein 96 is elevated in rheumatoid arthritis and activates macrophages primarily via TLR2 signaling. 
  • Hedgehog inhibits β-catenin activity in synovial joint development and osteoarthritis. 
  • High mobility group box chromosomal protein 1: a novel proinflammatory mediator in synovitis. 
  • Immunohistologic analysis of the distribution of cell adhesion molecules within the inflammatory synovial microenvironment. 
  • Increase in TCR gamma delta T lymphocytes in synovia from rheumatoid arthritis patients with active synovitis. 
  • Inflammation (or synovitis)-driven osteoarthritis: an opportunity for personalizing prognosis and treatment? 
  • Intercondylar synovial septum in two patients with nail-patella syndrome. 
  • Intra-articular clearance of labeled dextrans from naive and arthritic rat knee joints. 
  • Leukocyte homing to synovium. 
  • Localization of collagenase mRNA in rheumatoid arthritis synovium by in situ hybridization histochemistry. 
  • Loss of cartilage structure, stiffness, and frictional properties in mice lacking PRG4. 
  • MR imaging of infrapatellar plica injury. 
  • Malignant giant cell tumor of synovium (malignant pigmented villonodular synovitis). 
  • Measurement of an adhesion molecule as an indicator of inflammatory disease activity. Up-regulation of the receptor for hyaluronate (CD44) in rheumatoid arthritis. 
  • Mechanisms of prostanoid synthesis in human synovial cells: cytokine-peptide synergism. 
  • Methods for high-dimensional analysis of cells dissociated from cryopreserved synovial tissue 
  • Modulation of plasminogen activation and type IV collagenase activity by a synthetic peptide derived from the laminin A chain. 
  • Nitric oxide synthase and cyclooxygenase interactions in cartilage and meniscus: relationships to joint physiology, arthritis, and tissue repair. 
  • Pancarpal synovial and tenosynovial chondromatosis in a 65-year-old man: a highly unusual presentation of a common condition. 
  • Plasminogen activation stimulates an increase in intracellular calcium in human synovial fibroblasts. 
  • Prominent expression of mRNA for proinflammatory cytokines in synovium in patients with juvenile rheumatoid arthritis or chronic Lyme arthritis. 
  • Radiation synovectomy with 165Dy-FHMA: lymph node uptake and radiation dosimetry calculations. 
  • Recurrent para-articular chondroma of the ankle: a case report. 
  • Reply to "Does progranulin account for the opposite effects of etanercept and infliximab/adalimumab in osteoarthritis?" by Wei et al. 
  • Rheumatologic manifestations of cancer. 
  • Role of adhesion molecules in the pathogenesis of rheumatoid arthritis. 
  • Suppressive Effects of Insulin on Tumor Necrosis Factor-Dependent Early Osteoarthritic Changes Associated With Obesity and Type 2 Diabetes Mellitus. 
  • Synergistic Roles of Macrophages and Neutrophils in Osteoarthritis Progression. 
  • Synovectomy of the rheumatoid knee using intra-articular injection of dysprosium-165-ferric hydroxide macroaggregates. 
  • Synovial lipomatosis arborescens of the peroneal tendon sheath. 
  • Synovial microenvironment-T cell interactions. Human T cells bind to fibroblast-like synovial cells in vitro. 
  • Synovial plicae of the knee. 
  • TLR3 Ligand Poly(I:C) Exerts Distinct Actions in Synovial Fibroblasts When Delivered by Extracellular Vesicles. 
  • Targets to tackle--the pathophysiology of the disease. 
  • The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the guinea pig. 
  • The development of clinical signs of rheumatoid synovial inflammation is associated with increased synthesis of the chemokine CXCL8 (interleukin-8). 
  • The induction of matrix metalloproteinase and cytokine expression in synovial fibroblasts stimulated with immune cell microparticles. 
  • The role of innate immunity in osteoarthritis: when our first line of defense goes on the offensive. 
  • Therapeutic opportunities to prevent post-traumatic arthritis: Lessons from the natural history of arthritis after articular fracture. 
  • Thrombomodulin expression by human blood monocytes and by human synovial tissue lining macrophages. 
  • Transforming growth factor-beta 1 and 2 in the synovial-like interface membrane between implant and bone in loosening of total hip arthroplasty. 
  • Treatment of inflammatory arthritis via targeting of tristetraprolin, a master regulator of pro-inflammatory gene expression. 
  • Up-regulation of the alpha2-macroglobulin signaling receptor on rheumatoid synovial fibroblasts. 
  • Use of liposomes as carriers for radiation synovectomy. 
  • Value of biomarkers in osteoarthritis: current status and perspectives. 
  • Whipple's arthritis: direct detection of Tropheryma whippelii in synovial fluid and tissue.