T-Lymphocytes

• 

  Subject Areas on Research

  • "The very pulse of the machine": the tuberculous granuloma in motion. 
  • 'Chimeric' grafts assembled from multiple allodisparate donors enjoy enhanced transplant survival. 
  • 4,4'-Diisothiocyanatostilbene-2,2'-disulfonic acid inhibits CD3-T cell antigen receptor-stimulated Ca2+ influx in human T lymphocytes. 
  • A CD91-positive subset of CD11c+ blood dendritic cells: characterization of the APC that functions to enhance adaptive immune responses against CD91-targeted antigens. 
  • A Lennert lymphoma with a helper-T-cell phenotype. 
  • A Novel Carcinoembryonic Antigen T-Cell Bispecific Antibody (CEA TCB) for the Treatment of Solid Tumors. 
  • A Protocol for the Comprehensive Flow Cytometric Analysis of Immune Cells in Normal and Inflamed Murine Non-Lymphoid Tissues. 
  • A RNA interference screen identifies RIP3 as an essential inducer of TNF-induced programmed necrosis. 
  • A T cell intrinsic role of Id3 in a mouse model for primary Sjogren's syndrome. 
  • A birthday for B cells: Lymphopoiesis II, a scientific symposium honoring Max Cooper. 
  • A case of atypical, complete DiGeorge syndrome without 22q11 mutation. 
  • A cell-intrinsic role for Mst1 in regulating thymocyte egress. 
  • A change in the structure of Vbeta chromatin associated with TCR beta allelic exclusion. 
  • A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes. 
  • A comparison of murine T-cell-depleted adult bone marrow and full-term fetal blood cells in hematopoietic engraftment and immune reconstitution. 
  • A critical role for the autophagy gene Atg5 in T cell survival and proliferation. 
  • A crucial role for p80 TNF-R2 in amplifying p60 TNF-R1 apoptosis signals in T lymphocytes. 
  • A cytokine cocktail directly modulates the phenotype of DC-enriched anti-tumor T cells to convey potent anti-tumor activities in a murine model. 
  • A functional analysis of the spacer of V(D)J recombination signal sequences. 
  • A genetic investigation of E2A function in lymphocyte development. 
  • A global approach to tumor immunology. 
  • A human recombinant Fab identifies a human immunodeficiency virus type 1-induced conformational change in cell surface-expressed CD4. 
  • A large-scale method for the selective depletion of alphabeta T lymphocytes from PBSC for allogeneic transplantation. 
  • A metalloporphyrin-based superoxide dismutase mimic inhibits adoptive transfer of autoimmune diabetes by a diabetogenic T-cell clone. 
  • A neutralizing epitope of the superantigen SEA has agonist activity on T cells. 
  • A new look at blockade of T-cell costimulation: a therapeutic strategy for long-term maintenance immunosuppression. 
  • A novel activation pathway for mature thymocytes. Costimulation of CD2 (T,p50) and CD28 (T,p44) induces autocrine interleukin 2/interleukin 2 receptor-mediated cell proliferation. 
  • A novel approach for the analysis of T-cell reconstitution by using a T-cell receptor beta-based oligonucleotide microarray in hematopoietic stem cell transplantation. 
  • A novel polypeptide secreted by activated human T lymphocytes. 
  • A nuclear factor-kappaB inhibitor BAY11-7082 inhibits interactions between human endothelial cells, T cells, and monocytes. 
  • A one-step large-scale method for T- and B-cell depletion of mobilized PBSC for allogeneic transplantation. 
  • A phase I study of intratumoral ipilimumab and interleukin-2 in patients with advanced melanoma. 
  • A phase IIA randomized clinical trial of a multiclade HIV-1 DNA prime followed by a multiclade rAd5 HIV-1 vaccine boost in healthy adults (HVTN204). 
  • A pilot study of IL-2Rα blockade during lymphopenia depletes regulatory T-cells and correlates with enhanced immunity in patients with glioblastoma. 
  • A pilot trial targeting the ICOS-ICOS-L pathway in nonhuman primate kidney transplantation. 
  • A prospective clinical and immunologic analysis of patients with serum sickness. 
  • A regulatory B cell subset with a unique CD1dhiCD5+ phenotype controls T cell-dependent inflammatory responses. 
  • A replication-defective human adenovirus recombinant serves as a highly efficacious vaccine carrier. 
  • A retroviral-derived peptide phosphorylates protein kinase D/protein kinase Cmu involving phospholipase C and protein kinase C. 
  • A role for c-FLIP(L) in the regulation of apoptosis, autophagy, and necroptosis in T lymphocytes. 
  • A role for histone acetylation in the developmental regulation of VDJ recombination. 
  • A role for immunogenic DNA in the pathogenesis of systemic lupus erythematosus. 
  • A role for the cytoplasmic tail of the beta chain of CD8 in thymic selection. 
  • A role for the orphan steroid receptor Nur77 in apoptosis accompanying antigen-induced negative selection. 
  • A second human interleukin-2 binding protein that may be a component of high-affinity interleukin-2 receptors. 
  • A self-assembling peptide acting as an immune adjuvant. 
  • A signaling complex of Ca2+-calmodulin-dependent protein kinase IV and protein phosphatase 2A. 
  • A survival guide to early T cell development. 
  • A synthetic random basic copolymer with promiscuous binding to class II major histocompatibility complex molecules inhibits T-cell proliferative responses to major and minor histocompatibility antigens in vitro and confers the capacity to prevent murine graft-versus-host disease in vivo. 
  • A tale of two TRAPs: LAT and LAB in the regulation of lymphocyte development, activation, and autoimmunity. 
  • AD2, a human molecule involved in the interaction of T cells with epidermal keratinocytes and thymic epithelial cells. 
  • ADAM metallopeptidase domain 17 (ADAM17) is naturally processed through major histocompatibility complex (MHC) class I molecules and is a potential immunotherapeutic target in breast, ovarian and prostate cancers. 
  • ADAM10 is essential for proteolytic activation of Notch during thymocyte development. 
  • ADAPTIVE IMMUNE RESPONSE TO THERAPY IN HMGCR AUTOANTIBODY MYOPATHY 
  • AIDS-associated Kaposi's sarcoma: variables associated with survival. 
  • AIF Is "Always In Fashion" for T Cells. 
  • AMPK Is Essential to Balance Glycolysis and Mitochondrial Metabolism to Control T-ALL Cell Stress and Survival. 
  • ATP-binding cassette transporter G1 negatively regulates thymocyte and peripheral lymphocyte proliferation. 
  • Aberrant production of IL-13 by T cells promotes exocrinopathy in Id3 knockout mice. 
  • Abl family kinases modulate T cell-mediated inflammation and chemokine-induced migration through the adaptor HEF1 and the GTPase Rap1. 
  • Abl tyrosine kinases in T-cell signaling. 
  • Abnormalities in the regulation of human IgE synthesis. 
  • Accelerated development of immunity following transplantation of maternal marrow stem cells into infants with severe combined immunodeficiency and transplacentally acquired lymphoid chimerism. 
  • Accelerated induction of experimental allergic encephalomyelitis in PL/J mice by a non-V beta 8-specific superantigen. 
  • Accelerated thymic maturation and autoreactive T cells in bronchopulmonary dysplasia. 
  • Accessibility control of T cell receptor gene rearrangement in developing thymocytes. The TCR alpha/delta locus. 
  • Acquisition of a functional T cell receptor during T lymphocyte development is enforced by HEB and E2A transcription factors. 
  • Activated Akt promotes increased resting T cell size, CD28-independent T cell growth, and development of autoimmunity and lymphoma. 
  • Activation of T lymphocytes for adhesion and cytokine expression by toxin-conjugated anti-CD3 monoclonal antibodies. 
  • Activation of human B lymphocytes. X. Heterogeneity of concanavalin A-generated suppressor cells of the pokeweed mitogen-induced plaque-forming cell response of human peripheral blood lymphocytes. 
  • Activation of human B lymphocytes. XIV. Characterization of the precursor of the pokeweed mitogen-induced anti-sheep red blood cell plaque-forming cell. 
  • Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung tumors. 
  • Active immunotherapy for TNF-mediated inflammation using self-assembled peptide nanofibers. 
  • Active-specific immunization against melanoma: is the problem at the receiving end? 
  • Acute and chronic phagocyte determinants of cardiac allograft vasculopathy. 
  • Acute graft-versus-host disease: are we close to bringing the bench to the bedside? 
  • Acute lymphoblastic leukemia: classification and characterization with antisera to human T-cell and Ia antigens. 
  • Adenosine deaminase deficiency with late onset of recurrent infections: response to treatment with polyethylene glycol-modified adenosine deaminase. 
  • Adenosine deaminase deficiency with mosaicism for a "second-site suppressor" of a splicing mutation: decline in revertant T lymphocytes during enzyme replacement therapy. 
  • Adenovirus infection triggers a rapid, MyD88-regulated transcriptome response critical to acute-phase and adaptive immune responses in vivo. 
  • Adolescent nicotine: deficits in immune function. 
  • Adoptive immunotherapy for malignant glioma. 
  • Advances in the correction of immunodeficiency by bone marrow transplantation. 
  • Advances in the diagnosis and treatment of primary immunodeficiency diseases. 
  • Advances in the understanding and treatment of human severe combined immunodeficiency. 
  • Aerobic glycolysis suppresses p53 activity to provide selective protection from apoptosis upon loss of growth signals or inhibition of BCR-Abl. 
  • Age related changes in population of peripheral T cells: towards a model of immunosenescence. 
  • Akt-dependent glucose metabolism promotes Mcl-1 synthesis to maintain cell survival and resistance to Bcl-2 inhibition. 
  • Akt1 and Akt2 are required for alphabeta thymocyte survival and differentiation. 
  • Alefacept promotes co-stimulation blockade based allograft survival in nonhuman primates. 
  • Alemtuzumab for the prevention and treatment of graft-versus-host disease. 
  • Allelic exclusion of mouse T cell receptor alpha chains occurs at the time of thymocyte TCR up-regulation. 
  • Allelic exclusion of the T cell receptor alpha-chain: developmental regulation of a post-translational event. 
  • Allogeneic peripheral blood stem cell transplantation may be associated with a high risk of chronic graft-versus-host disease. 
  • Allograft airway fibrosis in the pulmonary milieu: a disorder of tissue remodeling. 
  • Alloimmune lung injury induced by local innate immune activation through inhaled lipopolysaccharide. 
  • Alteration of T-lymphocyte subpopulations in sarcoidosis. 
  • Altered decamer and nonamer from an HLA-A0201-restricted epitope of Survivin differentially stimulate T-cell responses in different individuals. 
  • Altered immune responses in apolipoprotein E-deficient mice. 
  • Altered lymphocyte populations in tumour invaded nodes of breast cancer patients. 
  • Alternative immunomodulatory strategies for xenotransplantation: CD40/154 pathway-sparing regimens promote xenograft survival. 
  • Alternative pathways for the selection of antigen-specific peripheral T cells. 
  • Amelioration of collagen-induced arthritis by CD95 (Apo-1/Fas)-ligand gene transfer. 
  • An alternative and effective HIV vaccination approach based on inhibition of antigen presentation attenuators in dendritic cells. 
  • An electronic method for counting human T and B cell rosettes. 
  • An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181a. 
  • An enhancer-blocking element between alpha and delta gene segments within the human T cell receptor alpha/delta locus. 
  • An expanded role of the tumor suppressor TSC1 in T cell tolerance. 
  • An interferon-β-resistant and NLRP3 inflammasome-independent subtype of EAE with neuronal damage. 
  • Analysis of Fc gamma receptors on human peripheral blood leukocytes by flow microfluorometry. I. Receptor distributions on monocytes, T gamma cells and cells labeled with the 3Al anti-T cell monoclonal antibody. 
  • Analysis of HLA A*02 association with vaccine efficacy in the RV144 HIV-1 vaccine trial. 
  • Analysis of expression of CD2, CD3, and T cell antigen receptor molecules during early human fetal thymic development. 
  • Analysis of primate renal allografts after T-cell depletion with anti-CD3-CRM9. 
  • Analysis of the human thymic perivascular space during aging. 
  • Analysis of the interaction of primate retroviruses with the human RNA interference machinery. 
  • Analysis of the mRNA targetome of microRNAs expressed by Marek's disease virus. 
  • Anti-AIDS agents. 42. Synthesis and anti-HIV activity of disubstituted (3'R,4'R)-3',4'-di-O-(S)-camphanoyl-(+)-cis-khellactone analogues. 
  • Anti-idiotypic antibodies as vaccine candidates. The immune network. 
  • Anti-receptor antibody-induced suppression of murine H-Y-specific delayed-type hypersensitivity responses. 
  • Anti-self HLA may be clonally expressed. 
  • Antibodies against the CD44 p80, lymphocyte homing receptor molecule augment human peripheral blood T cell activation. 
  • Antibody against T lymphoblastic leukemia-associated antigen (3-40) identifies vimentin and keratin intermediate filaments in normal cells. 
  • Antibody response to a T-dependent antigen requires B cell expression of complement receptors. 
  • Antibody valence and induced signal transduction: the role of antibody valence in anti-CD3-induced signal transduction in isolated normal T cells. 
  • Antibody, T-cell and dendritic cell immunotherapy for malignant brain tumors. 
  • Antibody-mediated B-cell depletion before adoptive immunotherapy with T cells expressing CD20-specific chimeric T-cell receptors facilitates eradication of leukemia in immunocompetent mice. 
  • Antibody-selected mimics of hepatitis C virus hypervariable region 1 activate both primary and memory Th lymphocytes. 
  • Antigenicity and immunogenicity of a synthetic human immunodeficiency virus type 1 group m consensus envelope glycoprotein. 
  • Antioxidants suppress mortality in the female NZB x NZW F1 mouse model of systemic lupus erythematosus (SLE). 
  • Antiviral antibodies are necessary for control of simian immunodeficiency virus replication. 
  • Apolipoprotein E-derived peptides ameliorate clinical disability and inflammatory infiltrates into the spinal cord in a murine model of multiple sclerosis. 
  • Apoptosis abnormalities of splenic lymphocytes in autoimmune lpr and gld mice. 
  • Apoptosis and autophagy in the regulation of T lymphocyte function. 
  • Arrested rearrangement of TCR V beta genes in thymocytes from children with X-linked severe combined immunodeficiency disease. 
  • Assessing immunophenotyping performance: proficiency-validation for adopting improved flow cytometry methods. 
  • Association of myosin light chain kinase with lymphocyte membrane-cytoskeleton complex. 
  • Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. 
  • Association of the human type C retrovirus with a subset of adult T-cell cancers. 
  • Attenuated PfSPZ Vaccine induces strain-transcending T cells and durable protection against heterologous controlled human malaria infection. 
  • Atypical lymphocytic angiitis of the optic nerve and central nervous system. 
  • Augmentation of tumor-specific immunity by upregulation of apoptotic melanoma cell calreticulin expression. 
  • Autoantibodies and their significance. 
  • Autocrine Complement Inhibits IL10-Dependent T-cell-Mediated Antitumor Immunity to Promote Tumor Progression. 
  • Autoimmune dacryoadenitis of NOD/LtJ mice and its subsequent effects on tear protein composition. 
  • Autoimmunity. The Fas track. 
  • Autophagy and lymphocyte homeostasis. 
  • Autophagy is essential for mitochondrial clearance in mature T lymphocytes. 
  • Autophagy regulates T lymphocyte proliferation through selective degradation of the cell-cycle inhibitor CDKN1B/p27Kip1. 
  • Autotaxin, an ectoenzyme that produces lysophosphatidic acid, promotes the entry of lymphocytes into secondary lymphoid organs. 
  • B cell antigen receptor endocytosis and antigen presentation to T cells require Vav and dynamin. 
  • B cell depletion reduces the development of atherosclerosis in mice. 
  • B cells in the pathophysiology of myasthenia gravis. 
  • B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies. 
  • B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB. 
  • B-lymphocyte effector functions in health and disease. 
  • BAFF is increased in renal transplant patients following treatment with alemtuzumab. 
  • Basement membranes and autoimmune diseases. 
  • Belatacept and sirolimus prolong nonhuman primate renal allograft survival without a requirement for memory T cell depletion. 
  • Beta adrenergic receptors in lymphocyte subpopulations. 
  • Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7. 
  • Beta-arrestin-2 regulates the development of allergic asthma. 
  • Beyond Oncolytics: E1B55K-Deleted Adenovirus as a Vaccine Delivery Vector. 
  • Bispecific antibodies engage T cells for antitumor immunotherapy. 
  • Blazing a new TRAIL in hematopoietic cell transplantation. 
  • Blockade of T- and B-lymphocyte development by antibody to the gamma c subunit of the receptors for interleukins 2, 4, and 7. 
  • Blocking CCR7 at the ocular surface impairs the pathogenic contribution of dendritic cells in allergic conjunctivitis. 
  • Both hematopoietic-derived and non-hematopoietic-derived {beta}-arrestin-2 regulates murine allergic airway disease. 
  • Breakthroughs in the understanding and therapy of primary immunodeficiency. 
  • Bromelain treatment of human T cells removes CD44, CD45RA, E2/MIC2, CD6, CD7, CD8, and Leu 8/LAM1 surface molecules and markedly enhances CD2-mediated T cell activation. 
  • C-C Motif Chemokine 5 Attenuates Angiotensin II-Dependent Kidney Injury by Limiting Renal Macrophage Infiltration. 
  • CAR T Cells Targeting Podoplanin Reduce Orthotopic Glioblastomas in Mouse Brains. 
  • CD154 blockade, sirolimus, and donor-specific transfusion prevents renal allograft rejection in cynomolgus monkeys despite homeostatic T-cell activation. 
  • CD20 deficiency in humans results in impaired T cell-independent antibody responses. 
  • CD28 costimulatory signal induces protein arginine methylation in T cells. 
  • CD28 ligation induces rapid tyrosine phosphorylation of the linker molecule LAT in the absence of Syk and ZAP-70 tyrosine phosphorylation. 
  • CD28 ligation induces tyrosine phosphorylation of Pyk2 but not Fak in Jurkat T cells. 
  • CD28 negative T cells: is their loss our gain? 
  • CD4 enhances T cell sensitivity to antigen by coordinating Lck accumulation at the immunological synapse. 
  • CD4+CD8+ T cells represent a significant portion of the anti-HIV T cell response to acute HIV infection. 
  • CD40 is a functional activation antigen and B7-independent T cell costimulatory molecule on normal human lung fibroblasts. 
  • CD40 ligand-dependent T cell activation: requirement of B7-CD28 signaling through CD40. 
  • CD40 mediated activation of gingival and periodontal ligament fibroblasts. 
  • CD44 antibody against In(Lu)-related p80, lymphocyte-homing receptor molecule inhibits the binding of human erythrocytes to T cells. 
  • CD44--a molecule involved in leukocyte adherence and T-cell activation. 
  • CD58/LFA-3 and IL-12 provided by activated monocytes are critical in the in vitro expansion of CD56+ T cells. 
  • CD6. 
  • CD69 gene is differentially regulated in T and B cells by evolutionarily conserved promoter-distal elements. 
  • CD7+, CD4-, CD8- acute leukemia: a syndrome of malignant pluripotent lymphohematopoietic cells. 
  • CD8+ T-cell alveolitis in familial pulmonary alveolar microlithiasis. 
  • CD83 influences cell-surface MHC class II expression on B cells and other antigen-presenting cells. 
  • CDX-1307: a novel vaccine under study as treatment for muscle-invasive bladder cancer. 
  • CFLAR/c-FLIPL: a star in the autophagy, apoptosis and necroptosis alliance. 
  • CTLA4Ig: bridging the basic immunology with clinical application. 
  • CXCL10/IP-10 is a biomarker and mediator for Kawasaki disease. 
  • CXCR3 and CCR5 ligands in rheumatoid arthritis synovium. 
  • Ca2+/calmodulin-dependent protein kinase IV and calcium signaling. 
  • Calcineurin mutants render T lymphocytes resistant to cyclosporin A. 
  • Calcium/calmodulin-dependent kinase IV in immune and inflammatory responses: novel routes for an ancient traveller. 
  • Calmodulin-dependent protein kinase IV regulates nuclear export of Cabin1 during T-cell activation. 
  • Can the thymus win the battle against drug-resistant HIV? 
  • Candidate counterparts of Sézary cells and adult T-cell lymphoma-leukaemia cells in normal peripheral blood: an ultrastructural study with the immunogold method and monoclonal antibodies. 
  • Cell adhesion molecules involved in intrathymic T cell development. 
  • Cell surface F1Fo ATP synthase: a new paradigm? 
  • Cell surface differentiation antigens of the malignant T cell in Sezary syndrome and mycosis fungoides. 
  • Cell-mediated immune responses to vaccine peptides derived from the circumsporozoite protein of Plasmodium falciparum. 
  • Cellular FLIP Inhibits Myeloid Cell Activation by Suppressing Selective Innate Signaling. 
  • Cellular anti-GP120 cytolytic reactivities in HIV-1 seropositive individuals. 
  • Cellular immune response to viral peptides in patients exposed to HIV. 
  • Cellular immune responses in neonates. 
  • Cellular immunity elicited by human immunodeficiency virus type 1/ simian immunodeficiency virus DNA vaccination does not augment the sterile protection afforded by passive infusion of neutralizing antibodies. 
  • Cellular requirements for anti-DNA production induced in mice by immunization with bacterial DNA. 
  • Cellular targeting in autoimmunity. 
  • Challenges in therapeutic strategies for transplantation: where now from here? 
  • Characteristics of alloreactive rat T cell lines established from low and high rejecting orthotopic liver transplants. 
  • Characterization and immunotherapeutic potential of gammadelta T-cells in patients with glioblastoma. 
  • Characterization of T lymphocyte and monocyte populations in HLA B8/DRw3 normal individuals and in patients with dermatitis herpetiformis. 
  • Characterization of a monoclonal antibody that defines an immunoregulatory T cell subset for immunoglobulin synthesis in humans. 
  • Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients. 
  • Characterization of cord blood natural killer and lymphokine activated killer lymphocytes following ex vivo cellular engineering. 
  • Characterization of cultured thymus tissue used for transplantation with emphasis on promiscuous expression of thyroid tissue-specific genes. 
  • Characterization of functional and phenotypic changes in anti-Gag vaccine-induced T cell responses and their role in protection after HIV-1 infection. 
  • Characterization of human CD7 transgenic mice. 
  • Characterization of human T lymphocytes that express the C3b receptor. 
  • Characterization of murine BATF: a negative regulator of activator protein-1 activity in the thymus. 
  • Characterization of the human B cell RAG-associated gene, hBRAG, as a B cell receptor signal-enhancing glycoprotein dimer that associates with phosphorylated proteins in resting B cells. 
  • Characterization of the interleukin-1-stimulated phospholipase C activity in human T lymphocytes. 
  • Characterization of thymus-derived lymphocyte subsets in acute Epstein-Barr virus-induced infectious mononucleosis. 
  • Characterizing the Switching Thresholds of Magnetophoretic Transistors. 
  • Checkpoint blockade in combination with cancer vaccines. 
  • Chemokine Signaling in Allergic Contact Dermatitis: Toward Targeted Therapies. 
  • Chemokines as adjuvants for immunotherapy: implications for immune activation with CCL3. 
  • Chromatin Dynamics and the Development of the TCRα and TCRδ Repertoires. 
  • Chromatin architecture, CCCTC-binding factor, and V(D)J recombination: managing long-distance relationships at antigen receptor loci. 
  • Chronic mucocutaneous candidiasis. Immunologic studies of three generations of a single family. 
  • Circulating adhesion molecules and inflammatory mediators in demyelination: a review. 
  • Clinical and immunologic effects of prolonged infusion of low-dose recombinant interleukin-2 after autologous and T-cell-depleted allogeneic bone marrow transplantation. 
  • Clinical application of whole-genome sequencing in patients with primary immunodeficiency. 
  • Clinicopathologic aspects of E rosette negative T cell acute lymphocytic leukemia: a Pediatric Oncology Group study. 
  • Cloning of a novel cell type from human fetal liver expressing cytoplasmic CD3 delta and epsilon but not membrane CD3. 
  • Cloning of murine splenic T lymphocytes and natural killer (NK) cells on filter paper discs: detection of a novel NK/T phenotype. 
  • Cloning, mapping, and characterization of activated leukocyte-cell adhesion molecule (ALCAM), a CD6 ligand. 
  • Co-delivery of antigen and IL-12 by Venezuelan equine encephalitis virus replicon particles enhances antigen-specific immune responses and antitumor effects. 
  • Combination Adenovirus and Protein Vaccines Prevent Infection or Reduce Viral Burden after Heterologous Clade C Simian-Human Immunodeficiency Virus Mucosal Challenge. 
  • Combined chemoseparation and immunoseparation of clonogenic T lymphoma cells from human bone marrow using 2'-deoxycoformycin, deoxyadenosine, 3A1 monoclonal antibody, and complement. 
  • Comparative analysis of antigen loading strategies of dendritic cells for tumor immunotherapy. 
  • Comparative immunogenicity in rhesus monkeys of multi-protein HIV-1 (CRF02_AG) DNA/MVA vaccines expressing mature and immature VLPs. 
  • Comparative structural analysis of HLA-A2 antigens distinguishable by cytotoxic T lymphocytes: variants M7 and DR1. 
  • Comparison of Minnesota antilymphoblast globulin and Upjohn antithymocyte globulin for induction immunosuppression of human renal allografts. 
  • Comparison of Viral Env Proteins from Acute and Chronic Infections with Subtype C Human Immunodeficiency Virus Type 1 Identifies Differences in Glycosylation and CCR5 Utilization and Suggests a New Strategy for Immunogen Design 
  • Comparison of anti-HIV-1 ADCC reactivities in infected humans and chimpanzees. 
  • Comparison of in vivo efficacy and mechanism of action of antimurine monoclonal antibodies directed against TCR alpha beta (H57-597) and CD3 (145-2C11). 
  • Comparison of outcomes of hematopoietic stem cell transplantation without chemotherapy conditioning by using matched sibling and unrelated donors for treatment of severe combined immunodeficiency. 
  • Competing Actions of Type 1 Angiotensin II Receptors Expressed on T Lymphocytes and Kidney Epithelium during Cisplatin-Induced AKI. 
  • Complete DiGeorge syndrome: development of rash, lymphadenopathy, and oligoclonal T cells in 5 cases. 
  • Complete DiGeorge syndrome: persistence of profound immunodeficiency. 
  • Complete hematologic and cytogenetic response to 2-amino-9-beta-D-arabinosyl-6-methoxy-9H-guanine in a patient with chronic myelogenous leukemia in T-cell blastic phase: a case report and review of the literature. 
  • Composite lymphoma of mycosis fungoides and cutaneous small B-cell lymphoma in a 73-year-old male patient. 
  • Computational investigations into the origins of short-term biochemical memory in T cell activation. 
  • Constitutive Notch signalling promotes CD4 CD8 thymocyte differentiation in the absence of the pre-TCR complex, by mimicking pre-TCR signals. 
  • Constitutive expression of a groEL-related protein on the surface of human gamma/delta cells. 
  • Control of CD4 gene expression: connecting signals to outcomes in T cell development. 
  • Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine. 
  • Control of thymic T cell maturation, deletion and egress by the RNA-binding protein HuR. 
  • Controlling lymphopoiesis with a combinatorial E-protein code. 
  • Conversion of a stem cell leukemia from a T-lymphoid to a myeloid phenotype induced by the adenosine deaminase inhibitor 2'-deoxycoformycin. 
  • Conversion of an immunogenic human immunodeficiency virus (HIV) envelope synthetic peptide to a tolerogen in chimpanzees by the fusogenic domain of HIV gp41 envelope protein. 
  • Cooperation between core binding factor and adjacent promoter elements contributes to the tissue-specific expression of interleukin-3. 
  • Coordinated posttranscriptional mRNA population dynamics during T-cell activation. 
  • Correct splicing despite mutation of the invariant first nucleotide of a 5' splice site: a possible basis for disparate clinical phenotypes in siblings with adenosine deaminase deficiency. 
  • Correction of proliferative responses in purine nucleoside phosphorylase (PNP)-deficient T lymphocytes by retroviral-mediated PNP gene transfer and expression. 
  • Correction of severe combined immunodeficiency by fetal liver cells. 
  • Corticosteroids regulate epithelial cell differentiation and Hassall body formation in the human thymus. 
  • Costimulation blockade: Towards clinical application 
  • Costimulation, coinhibition and cancer. 
  • Costimulatory molecules are active in the human xenoreactive T-cell response but not in natural killer-mediated cytotoxicity. 
  • Cowpox virus induces interleukin-10 both in vitro and in vivo. 
  • Cranial irradiation leads to acute and persistent neuroinflammation with delayed increases in T-cell infiltration and CD11c expression in C57BL/6 mouse brain. 
  • Creation of tolerogenic human dendritic cells via intracellular CTLA4: a novel strategy with potential in clinical immunosuppression. 
  • Cross-reacting antigens on L5178Y cells which serve as targets for cytotoxic T-lymphocyte lysis during establishment of the tumor dormant state. 
  • Cross-reactive potential of human T-lymphocyte responses in HIV-1 infection. 
  • Cross-subtype T-cell immune responses induced by a human immunodeficiency virus type 1 group m consensus env immunogen. 
  • Cross-subtype antibody and cellular immune responses induced by a polyvalent DNA prime-protein boost HIV-1 vaccine in healthy human volunteers. 
  • Cross-subtype antibody and cellular immune responses induced by a polyvalent DNA prime-protein boost HIV-1 vaccine in healthy human volunteers. 
  • Crosstalk Between T and B Cells in the Germinal Center After Transplantation. 
  • Cryopreserved Mesenchymal Stromal Cells Are Susceptible to T-Cell Mediated Apoptosis Which Is Partly Rescued by IFNγ Licensing. 
  • Current Knowledge and Priorities for Future Research in Late Effects after Hematopoietic Stem Cell Transplantation (HCT) for Severe Combined Immunodeficiency Patients: A Consensus Statement from the Second Pediatric Blood and Marrow Transplant Consortium International Conference on Late Effects after Pediatric HCT. 
  • Current Treatment, Emerging Translational Therapies, and New Therapeutic Targets for Autoimmune Myasthenia Gravis. 
  • Current status of adoptive immunotherapy of malignancies. 
  • Cutaneous T-cell lymphoma presenting as a rapidly enlarging ocular adnexal tumor. 
  • Cutaneous manifestations of serum sickness in patients receiving antithymocyte globulin. 
  • Cutting Edge: Localization of linker for activation of T cells to lipid rafts is not essential in T cell activation and development. 
  • Cutting edge: Rapamycin augments pathogen-specific but not graft-reactive CD8+ T cell responses. 
  • Cutting edge: Role of osteopontin and integrin αv in T cell-mediated anti-inflammatory responses in endotoxemia. 
  • Cyclic AMP modulates the functional plasticity of immature dendritic cells by inhibiting Src-like kinases through protein kinase A-mediated signaling. 
  • Cyclophosphamide diminishes inflammation and prolongs transgene expression following delivery of adenoviral vectors to mouse liver and lung. 
  • Cyclophosphamide plus ATG conditioning is insufficient for sustained hematopoietic reconstitution in patients with severe aplastic anemia transplanted with marrow from HLA-A, B, DRB matched unrelated donors. 
  • Cyclosporine A inhibits Ca2+-dependent stimulation of the Na+/H+ antiport in human T cells. 
  • Cytochalasins enhance the proliferation of CD4 cells through the CD3-Ti antigen receptor complex or the CD2 molecule through an effect on early events of activation. 
  • Cytokine-dependent and cytokine-independent roles for Mcl-1: genetic evidence for multiple mechanisms by which Mcl-1 promotes survival in primary T lymphocytes. 
  • Cytokines, leptin, and stress-induced thymic atrophy. 
  • Cytoplasmic domain truncation enhances fusion activity by the exterior glycoprotein complex of human immunodeficiency virus type 2 in selected cell types. 
  • Cytotoxic T lymphocyte antigen 4 (CTLA4) blockade accelerates the acute rejection of cardiac allografts in CD28-deficient mice: CTLA4 can function independently of CD28. 
  • DNA repair and epidemiology of basal cell carcinoma. 
  • DNA-MVA-protein vaccination of rhesus macaques induces HIV-specific immunity in mucosal-associated lymph nodes and functional antibodies. 
  • Defective Fc-receptor functions associated with the HLA-B8/DRw3 haplotype: studies in patients with dermatitis herpetiformis and normal subjects. 
  • Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency. 
  • Defective T cell development and function in the absence of Abelson kinases. 
  • Defective survival and activation of thymocytes in transgenic mice expressing a catalytically inactive form of Ca2+/calmodulin-dependent protein kinase IV. 
  • Deficient innate immunity, thymopoiesis, and gene expression response to radiation in survivors of childhood acute lymphoblastic leukemia. 
  • Delayed onset of infectious mononucleosis associated with acquired agammaglobulinemia and red cell aplasia. 
  • Deletion of CD4 and CD8 coreceptors permits generation of alphabetaT cells that recognize antigens independently of the MHC. 
  • Deletion of Trpm7 disrupts embryonic development and thymopoiesis without altering Mg2+ homeostasis. 
  • Delivery of CCL21 to metastatic disease improves the efficacy of adoptive T-cell therapy. 
  • Deltex1 redirects lymphoid progenitors to the B cell lineage by antagonizing Notch1. 
  • Demonstration of abnormalities in expression of thymic epithelial surface antigens in severe cellular immunodeficiency diseases. 
  • Demonstration of abnormalities in expression of thymic epithelial surface antigens in severe cellular immunodeficiency diseases. 
  • Dendritic Cells Enhance Polyfunctionality of Adoptively Transferred T Cells That Target Cytomegalovirus in Glioblastoma. 
  • Dendritic cell CD83: a therapeutic target or innocent bystander? 
  • Dendritic cell maturation in active immunotherapy strategies. 
  • Dendritic cell vaccines targeting survivin in head and neck cancer. 
  • Dendritic cells and the immunopathogenesis of idiopathic inflammatory myopathies. 
  • Dendritic cells cultured in anti-CD40 antibody-immobilized plates elicit a highly efficient peptide-specific T-cell response. 
  • Dendritic cells pulsed with pancreatic cancer total tumor RNA generate specific antipancreatic cancer T cells. 
  • Dendritic epidermal T cells regulate skin antimicrobial barrier function. 
  • Depressed interleukin-12-producing activity by monocytes correlates with adverse clinical course and a shift toward Th2-type lymphocyte pattern in severely injured male trauma patients. 
  • Dermatologic aspects of thyroid disease. 
  • Description of monoclonal antibody defining an HLA allotypic determinant that includes specificities within the B5 cross-reacting group. 
  • Detailed analysis of cytomegalovirus (CMV)-specific T cells expanded for adoptive immunotherapy of CMV infection following allogeneic stem cell transplantation for malignant disease. 
  • Detailed analysis of gene expression during development of T cell lineages in the thymus. 
  • Detection and partial characterization of human thymus-leukemia antigens. 
  • Detection of metastatic tumors in nude mice: brief communication. 
  • Detection of minimal residual T cell acute lymphoblastic leukemia by flow cytometry. 
  • Determinants of deoxyadenosine toxicity in hybrids between human T- and B- lymphoblasts as a model for the development of drug resistance in T-cell acute lymphoblastic leukemia. 
  • Determination of the functional status of alloreactive T cells by interferon-gamma kinetics. 
  • Development of a rapid whole blood flow cytometry procedure for the diagnosis of X-linked hyper-IgM syndrome patients and carriers. 
  • Development of immunity in human severe primary T cell deficiency following haploidentical bone marrow stem cell transplantation. 
  • Development of multiple monoclonal serum immunoglobulins (multiclonal gammopathy) following both HLA-identical unfractionated and T cell-depleted haploidentical bone marrow transplantation in severe combined immunodeficiency. 
  • Development of tolerogenic strategies in the clinic. 
  • Developmental activation of the TCR alpha enhancer requires functional collaboration among proteins bound inside and outside the core enhancer. 
  • Developmental regulation of V(D)J recombination at the TCR alpha/delta locus. 
  • Developmental regulation of VDJ recombination by the core fragment of the T cell receptor alpha enhancer. 
  • Developmental regulation of alpha beta T cell antigen receptor expression results from differential stability of nascent TCR alpha proteins within the endoplasmic reticulum of immature and mature T cells. 
  • Developmental regulation of lymphocyte-specific protein 1 (LSP1) expression in thymus during human T-cell maturation. 
  • Dextran sulfate sodium-induced colitis in immunodeficient rats. 
  • Diacylglycerol kinase ζ deficiency in a non-CD4(+) T-cell compartment leads to increased peanut hypersensitivity. 
  • Diacylglycerol kinases in immune cell function and self-tolerance. 
  • Different immune cells mediate mechanical pain hypersensitivity in male and female mice. 
  • Differential Requirements of TCR Signaling in Homeostatic Maintenance and Function of Dendritic Epidermal T Cells. 
  • Differential effects of donor-specific alloantibody. 
  • Differential expression of alternatively spliced pX mRNAs in HTLV-I-infected cell lines. 
  • Differential regulation of accessory mitogenic signaling receptors by the T cell antigen receptor. 
  • Differential regulation of leucocyte L-selectin (CD62L) expression in normal lymphoid and inflamed extralymphoid tissues. 
  • Differentiation of human T cells. 
  • Differentiation of human T lymphocytes. I. Acquisition of a novel human cell surface protein (p80) during normal intrathymic T cell maturation. 
  • Differentiation of human T lymphocytes: II. Phenotypic difference in skin and blood malignant T-cells in cutaneous T-cell lymphoma. 
  • Direct detection of cellular immune responses to cancer vaccines. 
  • Direct interaction between HLA-B and carbamazepine activates T cells in patients with Stevens-Johnson syndrome. 
  • Disruption of Mekk2 in mice reveals an unexpected role for MEKK2 in modulating T-cell receptor signal transduction. 
  • Disruption of diacylglycerol metabolism impairs the induction of T cell anergy. 
  • Disseminated Mycobacterium kansasii disease in complete DiGeorge syndrome. 
  • Distinct Epigenetic Effects of Tobacco Smoking in Whole Blood and among Leukocyte Subtypes. 
  • Diverse patterns of T-cell response against multiple newly identified human Y chromosome-encoded minor histocompatibility epitopes. 
  • Donor-derived regulatory B cells are important for suppression of murine sclerodermatous chronic graft-versus-host disease. 
  • Donor-reactive T-cell stimulation history and precursor frequency: barriers to tolerance induction. 
  • Down-regulation of IL-2 receptor alpha (CD25) characterizes human gammadelta-T cells rendered resistant to apoptosis after CD2 engagement in the presence of IL-12. 
  • Driving an improved CAR for cancer immunotherapy. 
  • Durable HIV-1 antibody and T-cell responses elicited by an adjuvanted multi-protein recombinant vaccine in uninfected human volunteers. 
  • Dynamic actin polymerization drives T cell receptor-induced spreading: a role for the signal transduction adaptor LAT. 
  • Dynamic microRNA gene transcription and processing during T cell development. 
  • Dysfunctional T cell metabolism in the tumor microenvironment. 
  • Dyshematopoiesis in combined immune deficiency with congenital neutropenia. 
  • Dystrophin immunity in Duchenne's muscular dystrophy. 
  • E proteins are required to activate germline transcription of the TCR Vbeta8.2 gene. 
  • E2A and HEB are required to block thymocyte proliferation prior to pre-TCR expression. 
  • ECDI-fixed allogeneic splenocytes induce donor-specific tolerance for long-term survival of islet transplants via two distinct mechanisms. 
  • EGFRvIII mCAR-modified T-cell therapy cures mice with established intracerebral glioma and generates host immunity against tumor-antigen loss. 
  • EGFRvIII-specific chimeric antigen receptor T cells migrate to and kill tumor deposits infiltrating the brain parenchyma in an invasive xenograft model of glioblastoma. 
  • ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation. 
  • Early events in human T cell ontogeny. Phenotypic characterization and immunohistologic localization of T cell precursors in early human fetal tissues. 
  • Early growth response 1 and NF-ATc1 act in concert to promote thymocyte development beyond the beta-selection checkpoint. 
  • Early-outgrowth of endothelial progenitor cells can function as antigen-presenting cells. 
  • Ectopic expression of the proto-oncogene Mer in pediatric T-cell acute lymphoblastic leukemia. 
  • Effect of an intravitreal cyclosporine implant on experimental uveitis in horses. 
  • Effect of thymectomy on peripheral lymphocyte subsets in myasthenia gravis: selective effect on T-cells in patients with thymic atrophy. 
  • Effective inactivation of human immunodeficiency virus with chlorhexidine antiseptics containing detergents and alcohol. 
  • Effects of cyclosporine in experimental cryptococcal meningitis. 
  • Effects of enzyme replacement therapy on immune function in ADA deficiency patient. 
  • Effects of murine cytomegalovirus infection on the immune response to a tumor allograft. 
  • Effects of mutational loss of adenosine kinase and deoxycytidine kinase on deoxyATP accumulation and deoxyadenosine toxicity in cultured CEM human T-lymphoblastoid cells. 
  • Efficacy and toxicity of 9-beta-D-arabinofuranosylguanine (araG) as an agent to purge malignant T cells from murine bone marrow: application to an in vivo T-leukemia model. 
  • Efficient nonviral Sleeping Beauty transposon-based TCR gene transfer to peripheral blood lymphocytes confers antigen-specific antitumor reactivity. 
  • Elimination of clonogenic malignant human T cells using monoclonal antibodies in combination with 2'-deoxycoformycin. 
  • Elimination of malignant clonogenic T cells from human bone marrow using chemoimmunoseparation with 2'-deoxycoformycin, deoxyadenosine and an immunotoxin. 
  • Emerging Skin T-Cell Functions in Response to Environmental Insults. 
  • Emerging immunotherapies for glioblastoma. 
  • Endocytosis and recycling of the T3-T cell receptor complex. The role of T3 phosphorylation. 
  • Engagement of the adhesion receptor CD22 triggers a potent stimulatory signal for B cells and blocking CD22/CD22L interactions impairs T-cell proliferation. 
  • Engraftment of human synovium into severe combined immune deficient mice. Migration of human peripheral blood T cells to engrafted human synovium and to mouse lymph nodes. 
  • Enhanced T cell responses due to diacylglycerol kinase zeta deficiency. 
  • Enhanced allergen-induced airway inflammation in paucity of lymph node T cell (plt) mutant mice. 
  • Enhanced dendritic cell antigen presentation in RNA-based immunotherapy. 
  • Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells. 
  • Enteral glutamine supplementation for very low birth weight infants decreases morbidity. 
  • Enteropathy-associated T cell lymphoma subtypes are characterized by loss of function of SETD2. 
  • Enumerating antigen-specific T-cell responses in peripheral blood: a comparison of peptide MHC Tetramer, ELISpot, and intracellular cytokine analysis. 
  • Epigallocatechin gallate affects human dendritic cell differentiation and maturation. 
  • Epithelial-thymocyte interactions in human thymus. 
  • Epitope-specific signaling through CD45 on T lymphocytes leads to cAMP synthesis in monocytes after ICAM-1-dependent cellular interaction. 
  • Epstein-Barr virus-associated posttransplantation lymphoproliferative disorder after high-dose immunosuppressive therapy and autologous CD34-selected hematopoietic stem cell transplantation for severe autoimmune diseases. 
  • Epstein-Barr virus-negative diffuse large B cell lymphoma with aberrant expression of CD3 and other T cell-associated antigens: report of three cases with a review of the literature. 
  • Epstein-Barr-associated leiomyomatosis and T-cell chimerism after haploidentical bone marrow transplantation for severe combined immunodeficiency disease. 
  • Estimating the probability of polyreactive antibodies 4E10 and 2F5 disabling a gp41 trimer after T cell-HIV adhesion. 
  • Estrogen-related receptor-α is a metabolic regulator of effector T-cell activation and differentiation. 
  • Evaluation of lymphocyte differentiation in primary and secondary immunodeficiency diseases. 
  • Evidence for immune-mediated reduction of viral replication in Macaca nemestrina mucosally immunized with inactivated SHIV(89.6). 
  • Evidence for susceptibility of intrathymic T-cell precursors and their progeny carrying T-cell antigen receptor phenotypes TCR alpha beta + and TCR gamma delta + to human immunodeficiency virus infection: a mechanism for CD4+ (T4) lymphocyte depletion. 
  • Ex vivo expanded human Vgamma9Vdelta2+ gammadelta-T cells mediate innate antitumor activity against human prostate cancer cells in vitro. 
  • Ex vivo expansion, maturation, and activation of umbilical cord blood-derived T lymphocytes with IL-2, IL-12, anti-CD3, and IL-7. Potential for adoptive cellular immunotherapy post-umbilical cord blood transplantation. 
  • Ex vivo spermine dialdehyde treatment prevents lethal GVHD in a murine bone marrow transplantation model. 
  • Expanded breadth of the T-cell response to mosaic human immunodeficiency virus type 1 envelope DNA vaccination. 
  • Expansion of tumor-T cell pairs from fine needle aspirates of melanoma metastases. 
  • Expansion or elimination of B cells in vivo: dual roles for CD40- and Fas (CD95)-ligands modulated by the B cell antigen receptor. 
  • Expansions of NK-like αβT cells with chronologic aging: novel lymphocyte effectors that compensate for functional deficits of conventional NK cells and T cells. 
  • Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis. 
  • Expression of Mls determinants in mice exhibiting the severe combined immunodeficiency (scid) mutation or X-linked immunodeficiency (xid) defect. 
  • Expression of T-lymphoblast-encoded HLA-DR antigens on human T-B lymphoblast hybrids. 
  • Expression of T-lymphoblast-encoded HLA-DR, MT, and SB antigens on human T-B lymphoblast hybrids. 
  • Expression of a wide T cell receptor V beta repertoire in human T lymphocytes derived in vitro from embryonic liver cell precursors. 
  • Expression of class I histocompatibility antigens on human T-B lymphoblast hybrids. 
  • Expression of cytokine mRNA in murine splenic dendritic cells and better induction of T cell-derived cytokines by dendritic cells than by macrophages during in vitro costimulation assay using specific antigens. 
  • Expression of early activation antigen (CD69) during human thymic development. 
  • Expression of human T cell receptor-gamma delta structural forms. 
  • Expression of human interleukin-3 (multi-CSF) is restricted to human lymphocytes and T-cell tumor lines. 
  • Expression of intercellular adhesion molecule (ICAM)-1 or ICAM-2 is critical in determining sensitivity of pancreatic cancer cells to cytolysis by human gammadelta-T cells: implications in the design of gammadelta-T-cell-based immunotherapies for pancreatic cancer. 
  • Expression of multiple chemokine genes by a human mast cell leukemia. 
  • Expression of the CD7 ligand K-12 in human thymic epithelial cells: regulation by IFN-gamma. 
  • Expression of the gene defect in X-linked agammaglobulinemia. 
  • Extensive junctional diversity of rearranged human T cell receptor delta genes. 
  • FKBP12 is the only FK506 binding protein mediating T-cell inhibition by the immunosuppressant FK506. 
  • FOXN1 mutation abrogates prenatal T-cell development in humans. 
  • FTY720 stimulates multidrug transporter- and cysteinyl leukotriene-dependent T cell chemotaxis to lymph nodes. 
  • Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands. 
  • First-in-man application of a novel therapeutic cancer vaccine formulation with the capacity to induce multi-functional T cell responses in ovarian, breast and prostate cancer patients. 
  • Flow cytometry analysis of adenosine deaminase (ADA) expression: a simple and reliable tool for the assessment of ADA-deficient patients before and after gene therapy. 
  • Fluorescence-based measurement of cystine uptake through xCT shows requirement for ROS detoxification in activated lymphocytes. 
  • Follicular mucinosis as a presenting sign of acute myeloblastic leukemia. 
  • Follicular mucinosis as a presenting sign of acute myeloblastic leukemia. 
  • FoxO-dependent regulation of diacylglycerol kinase α gene expression. 
  • Frequency of MART-1/MelanA and gp100/PMel17-specific T cells in tumor metastases and cultured tumor-infiltrating lymphocytes. 
  • Frequent detection and isolation of cytopathic retroviruses (HTLV-III) from patients with AIDS and at risk for AIDS. 
  • Fulfilling the promise of immunotherapy. 
  • Function of the LFA-1 and T4 molecules in the direct activation of resting human B lymphocytes by T lymphocytes. 
  • Functional association of CD7 with phosphatidylinositol 3-kinase: interaction via a YEDM motif. 
  • Functional coordination and HuR-mediated regulation of mRNA stability during T cell activation. 
  • Functional development of the T cell receptor for antigen 
  • Functional markers: a new perspective on malignant lymphomas. 
  • Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis. 
  • Functions of E2A-HEB heterodimers in T-cell development revealed by a dominant negative mutation of HEB. 
  • Functions of skin-resident γδ T cells. 
  • Further investigation of simian immunodeficiency virus Vif function in human cells. 
  • G protein-coupled receptor kinase 2 in multiple sclerosis and experimental autoimmune encephalomyelitis. 
  • GPI-defective monocytes from paroxysmal nocturnal hemoglobinuria patients show impaired in vitro dendritic cell differentiation. 
  • Gamma (immune) interferon produced by leukocytes from a patients with a T cell proliferation disease. 
  • Gamma (immune) interferon production by leukocytes from a patient with a TG cell proliferative disease. 
  • Gastrin-releasing peptide, immune responses, and lung disease. 
  • Gastroesophageal reflux-associated aspiration alters the immune response in asthma. 
  • Gene duplications at the chemokine locus on mouse chromosome 4: multiple strain-specific haplotypes and the deletion of secondary lymphoid-organ chemokine and EBI-1 ligand chemokine genes in the plt mutation. 
  • Gene expression profiling of anticancer immune responses. 
  • Gene therapy for human SCID: dreams become reality. 
  • Generation of CAR T cells for adoptive therapy in the context of glioblastoma standard of care. 
  • Generation of Dhx9-deficient clones in T-cell development with a mitotic recombination technique. 
  • Generation of anti-idiotypic reagents in the EGFRvIII tumor-associated antigen system. 
  • Generation of mucosal anti-human immunodeficiency virus type 1 T-cell responses by recombinant Mycobacterium smegmatis. 
  • Genes regulating HLA class I antigen expression in T-B lymphoblast hybrids. 
  • Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells. 
  • Genetic analysis of MRL-lpr mice: relationship of the Fas apoptosis gene to disease manifestations and renal disease-modifying loci. 
  • Genetic analysis of intracranial tumors in a murine model of glioma demonstrate a shift in gene expression in response to host immunity. 
  • Genotype, phenotype, and outcomes of nine patients with T-B+NK+ SCID. 
  • Germinal center formation, immunoglobulin class switching, and autoantibody production driven by "non alpha/beta" T cells. 
  • Germline transcription from T-cell receptor Vbeta gene is uncoupled from allelic exclusion. 
  • Glimpse of natural selection of long-lived T-cell clones in healthy life. 
  • Glucose metabolism attenuates p53 and Puma-dependent cell death upon growth factor deprivation. 
  • Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival. 
  • Glucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways. 
  • Graft survival in a rhesus renal transplant model after immunotoxin-mediated T-cell depletion is enhanced by mycophenolate and steroids. 
  • Graft-versus-host reactions: anti-leukemia effects of donor T cells. 
  • Granulocyte-macrophage colony-stimulating factor and interleukin-3 mRNAs are produced by a small fraction of blood mononuclear cells. 
  • Greater chemotherapy-induced lymphopenia enhances tumor-specific immune responses that eliminate EGFRvIII-expressing tumor cells in patients with glioblastoma. 
  • Growth hormone accelerates immune recovery following allogeneic T-cell-depleted bone marrow transplantation in mice. 
  • Growth-dependent regulation of cellular ceramides in human T-cells. 
  • Guanine arabinoside as a bone marrow-purging agent. 
  • Gut immune maturation depends on colonization with a host-specific microbiota. 
  • H-2K-, H-21- and H-2D-restricted hybridoma contact sensitivity effector cells. 
  • HER2 dendritic cell vaccines. 
  • HIV infection and the dynamic interplay between the thymus and the peripheral T cell pool. 
  • HIV infection--induced posttranslational modification of T cell signaling molecules associated with disease progression. 
  • HIV-1 CD4-induced (CD4i) gp120 epitope vaccines promote B and T-cell responses that contribute to reduced viral loads in rhesus macaques. 
  • HIV-1 Nef protein: An invitation to a kill. 
  • HIV-1 infection of human T lymphocytes results in enhanced alpha 5 beta 1 integrin expression. 
  • HIV-1 infection stimulates T cell invasiveness and synthesis of the 92-kDa type IV collagenase. 
  • HIV-1 neutralization profile and plant-based recombinant expression of actinohivin, an Env glycan-specific lectin devoid of T-cell mitogenic activity. 
  • HIV-1-induced cell fusion is mediated by multiple regions within both the viral envelope and the CCR-5 co-receptor. 
  • HIV-DNA priming alters T cell responses to HIV-adenovirus vaccine even when responses to DNA are undetectable. 
  • HLA class II molecules on monocytes regulate T cell proliferation through physical interaction in the CD3 activation pathway. 
  • HPV clearance and the neglected role of stochasticity. 
  • Hairy cell leukemia-associated familial lymphoproliferative disorder: immunologic abnormalities in unaffected family members. 
  • Haploidentical bone marrow stem cell transplantation in human severe combined immunodeficiency. 
  • Hapten-specific T cell response to 4-hydroxy-3-nitrophenyl acetyl. X. Characterization of distinct T cell subsets mediating cutaneous sensitivity responses. 
  • Hapten-specific T cell responses to 4-hydroxy-3-nitrophenyl acetyl. 
  • Hapten-specific T cell responses to 4-hydroxy-3-nitrophenyl acetyl. VI. Evidence for different T cell receptors in cells that mediate H-21-restricted and H-2D-restricted cutaneous sensitivity responses. 
  • Hapten-specific T cell responses to 4-hydroxy-3-nitrophenyl acetyl. VIII. Suppressor cell pathways in cutaneous sensitivity responses. 
  • Hematopoietic chimerism achieved by in utero hematopoietic stem cell injection does not induce donor-specific tolerance for renal allografts in sheep. 
  • Hematopoietic stem cell dose correlates with the speed of immune reconstitution after stem cell transplantation. 
  • Hematopoietic stem cell transplantation for severe combined immunodeficiency in the neonatal period leads to superior thymic output and improved survival. 
  • Hematopoietic stem-cell transplantation for the treatment of severe combined immunodeficiency. 
  • Heparan sulfate is a plasma biomarker of acute cellular allograft rejection. 
  • Heparan sulfate, an endogenous TLR4 agonist, promotes acute GVHD after allogeneic stem cell transplantation. 
  • Heterogeneity of acute lymphocytic leukemia cell surface markers as detected by monoclonal antibodies. 
  • Heterogeneity of lymphocyte subpopulations in severe combined immunodeficiency. Evidence against a stem cell defect. 
  • Heterogeneity of phenotype in two siblings with adenosine deaminase deficiency. 
  • Heterologous envelope immunogens contribute to AIDS vaccine protection in rhesus monkeys. 
  • Hierarchical Bayesian mixture modelling for antigen-specific T-cell subtyping in combinatorially encoded flow cytometry studies. 
  • High incidence of T-cell tumors in E2A-null mice and E2A/Id1 double-knockout mice. 
  • High-frequency alloreactive T cells augment effector function of low-frequency CD8+ T-cell responses under CD28/CD154 blockade. 
  • High-resolution, noninvasive longitudinal live imaging of immune responses. 
  • High-throughput sequencing detects minimal residual disease in acute T lymphoblastic leukemia. 
  • Highlights from the 46 th annual meeting of the American Society of Hematology. 
  • Histopathologic features of rejecting orthotopic corneal xenografts. 
  • Host genetic determinants of T cell responses to the MRKAd5 HIV-1 gag/pol/nef vaccine in the step trial. 
  • How and why do T cells and their derived cytokines affect the injured and healthy brain? 
  • Human Epistatic Interaction Controls IL7R Splicing and Increases Multiple Sclerosis Risk. 
  • Human IgE biosynthesis in vitro: studies with atopic and normal blood mononuclear cells and subpopulations. 
  • Human T cell antigen expression by primate T cells. 
  • Human T cell antigen expression during the early stages of fetal thymic maturation. 
  • Human T cell receptor-gamma and -delta chain pairing analyzed by transfection of a T cell receptor-delta negative mutant cell line. 
  • Human T cell reconstitution in DiGeorge syndrome and HIV-1 infection. 
  • Human T lymphocyte antigens as defined by monoclonal antibodies. 
  • Human T-B lymphoblast hybrids express HLA-DR specificities not expressed by either parent. 
  • Human T-cell leukemia virus type 1 tax attenuates the ATM-mediated cellular DNA damage response. 
  • Human T-cell leukemia/lymphoma virus: studies of host-virus interaction. 
  • Human T-cell lymphotropic virus IIIB glycoprotein (gp120) bound to CD4 determinants on normal lymphocytes and expressed by infected cells serves as target for immune attack. 
  • Human T-cell tumours containing chromosome 14 inversion or translocation with breakpoints proximal to immunoglobulin joining regions at 14q32. 
  • Human antiporcine mixed lymphocyte reaction. 
  • Human dendritic cells, pulsed with either melanoma tumor cell lysates or the gp100 peptide(280-288), induce pairs of T-cell cultures with similar phenotype and lytic activity. 
  • Human epidermal keratinocytes are induced to secrete interleukin-6 and co-stimulate T lymphocyte proliferation by a CD40-dependent mechanism. 
  • Human equivalent of the mouse Nude/SCID phenotype: long-term evaluation of immunologic reconstitution after bone marrow transplantation. 
  • Human immunodeficiency virus type 1 infection despite prior immunization with a recombinant envelope vaccine regimen. 
  • Human immunodeficiency virus. Chaperoning a pathogen. 
  • Human intrathymic T cell differentiation. 
  • Human lymphocyte antigens: production of a monoclonal antibody that defines functional thymus-derived lymphocyte subsets. 
  • Human lymphocyte motility: normal characteristics and anomalous behavior of chronic lymphocytic leukemia cells. 
  • Human lymphocyte proliferation responses following primary immunization with rabies vaccine as neoantigen. 
  • Human medullary thymocyte p80 antigen and In(Lu)-related p80 antigen reside on the same protein. 
  • Human monocytes as intermediaries between allogeneic endothelial cells and allospecific T cells: a role for direct scavenger receptor-mediated endothelial membrane uptake in the initiation of alloimmunity. 
  • Human nasopharyngeal-associated lymphoreticular tissues. Functional analysis of subepithelial and intraepithelial B and T cells from adenoids and tonsils. 
  • Human placental cytotrophoblasts attract monocytes and CD56(bright) natural killer cells via the actions of monocyte inflammatory protein 1alpha. 
  • Human platelets activate porcine endothelial cells through a CD154-dependent pathway. 
  • Human postnatal CD4- CD8- CD3- thymic T cell precursors differentiate in vitro into T cell receptor delta-bearing cells. 
  • Human retrovirus-related synthetic peptides inhibit T lymphocyte proliferation. 
  • Human serum sickness. 
  • Human serum sickness: a prospective analysis of 35 patients treated with equine anti-thymocyte globulin for bone marrow failure. 
  • Human spleen contains phenotypic subsets of macrophages and dendritic cells that occupy discrete microanatomic locations. 
  • Human splenic sinusoidal lining cells express antigens associated with monocytes, macrophages, endothelial cells, and T lymphocytes. 
  • Human thymic epithelial cells directly induce activation of autologous immature thymocytes. 
  • Human thymic epithelial cells function as accessory cells for autologous mature thymocyte activation. 
  • Human thymic epithelial cells produce IL-6, granulocyte-monocyte-CSF, and leukemia inhibitory factor. 
  • Human thymic epithelium and T cell development: current issues and future directions. 
  • Humoral autoimmunity in mice overexpressing B cell surface CD19: vital role for MHC class II. 
  • Humoral immune responses in L-selectin-deficient mice. 
  • Hyper IgM syndrome associated with defective CD40-mediated B cell activation. 
  • ICAM-1 (CD54) expression on B lymphocytes is associated with their costimulatory function and can be increased by coactivation with IL-1 and IL-7. 
  • ICON: the early diagnosis of congenital immunodeficiencies. 
  • IL-1 receptors: structure and signals. 
  • IL-12/GM-CSF coadministration in an SIV DNA prime/protein boost protocol enhances Gag-specific T cells but not virus-specific neutralizing antibodies in rhesus macaques. 
  • IL-1β-dependent activation of dendritic epidermal T cells in contact hypersensitivity. 
  • IL-2, IL-4, and IFN-gamma gene expression versus secretion in superantigen-activated T cells. Distinct requirement for costimulatory signals through adhesion molecules. 
  • IL-2-induced CD4+ T-cell expansion in HIV-infected patients is associated with long-term decreases in T-cell proliferation. 
  • IL-7 engages multiple mechanisms to overcome chronic viral infection and limit organ pathology. 
  • IL-7 enhances the survival and maintains the size of naive T cells. 
  • IL-7 is essential for homeostatic control of T cell metabolism in vivo. 
  • IL-7 promotes Glut1 trafficking and glucose uptake via STAT5-mediated activation of Akt to support T-cell survival. 
  • Ia+ T cells in new onset Graves' disease. 
  • Identification and utilization of arbitrary correlations in models of recombination signal sequences. 
  • Identification of App1 as a regulator of phagocytosis and virulence of Cryptococcus neoformans. 
  • Identification of Functional and Expression Polymorphisms Associated With Risk for Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis. 
  • Identification of a 43-kilodalton human T lymphocyte membrane protein as a receptor for pertussis toxin. 
  • Identification of alpha-melanocyte stimulating hormone as a potential immunosuppressive factor in aqueous humor. 
  • Identification of an essential site for transcriptional activation within the human T-cell receptor delta enhancer. 
  • Identification of human T cell leukemia virus in a Japanese patient with adult T cell leukemia and cutaneous lymphomatous vasculitis. 
  • Identification of human and mouse p19, a novel CDK4 and CDK6 inhibitor with homology to p16ink4. 
  • Identification of putative human T cell receptor delta complementary DNA clones. 
  • Identification of subpopulations of mononuclear cells in cutaneous infiltrates. I. Differentiation between B cells, T cells, and histiocytes. 
  • Identification of transforming growth factor-beta as an immunosuppressive factor in aqueous humor. 
  • Idiopathic CD4+ T-lymphocytopenia. 
  • IgE Fc receptor positive T and B lymphocytes in patients with the hyper IgE syndrome. 
  • IgE Fc receptor positive T, B and NK cells in patients with the hyper-IgE syndrome. 
  • Immature human thymocytes can be driven to differentiate into nonlymphoid lineages by cytokines from thymic epithelial cells. 
  • Immune (gamma) interferon production by a murine T cell lymphoma: requirements for macromolecular synthesis and lack of relationship with cell cycle. 
  • Immune function during intravenous administration of a soybean oil emulsion. 
  • Immune pathogenesis of heparin-induced thrombocytopenia. 
  • Immune reconstitution after unrelated cord blood transplantation. 
  • Immune reconstitution in patients with HIV infection. 
  • Immune recovery in adult patients after myeloablative dual umbilical cord blood, matched sibling, and matched unrelated donor hematopoietic cell transplantation. 
  • Immune status assay (ISA): a noninvasive procedure for studying allograft rejection. 
  • Immune surveillance by mast cells during dengue infection promotes natural killer (NK) and NKT-cell recruitment and viral clearance. 
  • Immunity to malaria after administration of ultra-low doses of red cells infected with Plasmodium falciparum. 
  • Immunization with an SIV-based IDLV Expressing HIV-1 Env 1086 Clade C Elicits Durable Humoral and Cellular Responses in Rhesus Macaques. 
  • Immunization with cocktail of HIV-derived peptides in montanide ISA-51 is immunogenic, but causes sterile abscesses and unacceptable reactogenicity. 
  • Immunodominant liver-specific expression suppresses transgene-directed immune responses in murine pompe disease. 
  • Immunodominant sites of human T cell lymphotropic virus type 1 envelope protein for murine helper T cells. 
  • Immunofluorescent analysis of expression of the RNA tumor virus major glycoprotein, gp71, on the surfaces of normal murine cells. 
  • Immunogenicity of a vaccine regimen composed of simian immunodeficiency virus DNA, rMVA, and viral particles administered to female rhesus macaques via four different mucosal routes. 
  • Immunogenicity of attenuated vesicular stomatitis virus vectors expressing HIV type 1 Env and SIV Gag proteins: comparison of intranasal and intramuscular vaccination routes. 
  • Immunohistologic analysis of the distribution of cell adhesion molecules within the inflammatory synovial microenvironment. 
  • Immunologic and clinicopathologic features of common acute lymphoblastic leukemia antigen-positive childhood T-cell leukemia. A Pediatric Oncology Group Study. 
  • Immunologic aspects of monoclonal B-cell lymphocytosis. 
  • Immunologic basis for allopurinol-induced severe cutaneous adverse reactions: HLA-B*58:01-restricted activation of drug-specific T cells and molecular interaction. 
  • Immunologic monitoring of cancer vaccine therapy: results of a workshop sponsored by the Society for Biological Therapy. 
  • Immunologic studies on T and B lymphocytes in chimpanzees: effects of thymectomy and irradiation. 
  • Immunologic tolerance. 
  • Immunological and clinical responses in metastatic renal cancer patients vaccinated with tumor RNA-transfected dendritic cells. 
  • Immunological disruption of antiangiogenic signals by recruited allospecific T cells leads to corneal allograft rejection. 
  • Immunological findings in thymoma and thymoma-related syndromes. 
  • Immunological responses in a patient with glioblastoma multiforme treated with sequential courses of temozolomide and immunotherapy: case study. 
  • Immunomagnetic selection of purified monocyte and lymphocyte populations from peripheral blood mononuclear cells following cryopreservation. 
  • Immunomodulator effect of picroliv and its potential in treatment against resistant Plasmodium yoelii (MDR) infection in mice. 
  • Immunomodulatory peptides with high binding affinity for class II MHC molecules for the prevention of graft-versus-host disease. 
  • Immunoregulatory T cells in cancer immunotherapy. 
  • Immunoregulatory aberrations in systemic lupus erythematosus. 
  • Immunoregulatory disorders associated with hereditary angioedema. II. Serologic and cellular abnormalities. 
  • Immunoregulatory mechanisms of the eye. 
  • Immunosenescence of ageing. 
  • Immunosuppressive protocols and immunological challenges related to hand transplantation. 
  • Immunosuppressive therapies in myasthenia gravis. 
  • Immunotherapy and Checkpoint Inhibitors in Recurrent and Metastatic Head and Neck Cancer. 
  • Immunotoxin FN18-CRM9 induces stronger T cell signaling than unconjugated monoclonal antibody FN18. 
  • Impact of pronase on flow cytometric crossmatch outcome. 
  • Improving defences at the portal of HIV entry: mucosal and innate immunity. 
  • Improving the outcome of umbilical cord blood transplantation through ex vivo expansion or graft manipulation. 
  • In Vitro Pre-Clinical Validation of Suicide Gene Modified Anti-CD33 Redirected Chimeric Antigen Receptor T-Cells for Acute Myeloid Leukemia. 
  • In Vivo Fluorescence Imaging of the Activity of CEA TCB, a Novel T-Cell Bispecific Antibody, Reveals Highly Specific Tumor Targeting and Fast Induction of T-Cell-Mediated Tumor Killing. 
  • In situ and systemic cellular immunity associated with orthotopic rat liver allograft acceptance or rejection. 
  • In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability. 
  • In utero transplantation of rat hematopoietic stem cells induces xenogeneic chimerism in mice. 
  • In vitro analysis of the human antiporcine T-cell repertoire. 
  • In vitro and in vivo human T cell repertoire in kidney allograft rejection. 
  • In vitro autoantibody production by normal adult and cord blood B cells. 
  • In vitro growth and phenotypic characterization of mesodermal-derived and epithelial components of normal and abnormal human thymus. 
  • In vitro priming and expansion of cytomegalovirus-specific Th1 and Tc1 T cells from naive cord blood lymphocytes. 
  • In vivo T cell costimulation blockade with abatacept for acute graft-versus-host disease prevention: a first-in-disease trial. 
  • In vivo models of human lymphopoiesis and autoimmunity in severe combined immune deficient mice. 
  • Incidence and clinical significance of cardiac biomarker elevation during stem cell mobilization, apheresis, and intramyocardial delivery: an analysis from ACT34-CMI. 
  • Increase in TCR gamma delta T lymphocytes in synovia from rheumatoid arthritis patients with active synovitis. 
  • Increased IL-4 production and attenuated proliferative and pro-inflammatory responses of splenocytes from wild-caught rats (Rattus norvegicus). 
  • Increased accumulation of tissue ACE in human atherosclerotic coronary artery disease. 
  • Increased biodiversity in the environment improves the humoral response of rats. 
  • Increased circulating Ia-antigen-bearing T cells in type I diabetes mellitus. 
  • Increased inflammation but similar physical composition and function in older-aged, HIV-1 infected subjects. 
  • Increased production of IL-4 by gut T-cell lines from patients with dermatitis herpetiformis compared to patients with isolated gluten-sensitive enteropathy. 
  • Increased vaccine-specific T cell frequency after peptide-based vaccination correlates with increased susceptibility to in vitro stimulation but does not lead to tumor regression. 
  • Inducing unresponsiveness by the use of anti-CD3 immunotoxin, CTLA4-Ig, and anti-CD40 ligand. 
  • Induction of CD4(+) and CD8(+) T-cell responses to the human stromal antigen, fibroblast activation protein: implication for cancer immunotherapy. 
  • Induction of CD56 and TCR-independent activation of T cells with aging. 
  • Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires. 
  • Induction of HIV-1 broad neutralizing antibodies in 2F5 knock-in mice: selection against membrane proximal external region-associated autoreactivity limits T-dependent responses. 
  • Induction of HIVMN neutralizing antibodies in primates using a prime-boost regimen of hybrid synthetic gp120 envelope peptides. 
  • Induction of T cell CD7 gene transcription by nonmitogenic ionomycin-induced transmembrane calcium flux. 
  • Induction of hsp70-mediated Th17 autoimmunity can be exploited as immunotherapy for metastatic prostate cancer. 
  • Induction of human dendritic cell maturation using transfection with RNA encoding a dominant positive toll-like receptor 4. 
  • Induction of immune responses by schistosome granuloma macrophages. 
  • Induction of immune responses with anti-idiotypic antibodies: implications for the induction of protective immunity. 
  • Induction of immunity to human immunodeficiency virus type-1 by vaccination. 
  • Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement. 
  • Infection of the HTLV-II-bearing T-cell line C3 with HTLV-III/LAV is highly permissive and lytic. 
  • Infection with Francisella tularensis LVS clpB leads to an altered yet protective immune response. 
  • Inherited DOCK2 Deficiency in Patients with Early-Onset Invasive Infections. 
  • Inhibition by anti-HLA class II monoclonal antibodies of monoclonal antibody OKT3-induced T cell proliferation. Studies at the mRNA level. 
  • Inhibition of HIV type 1 infection of mononuclear phagocytes by anti-CD44 antibodies. 
  • Inhibition of HIV-1 proviral DNA synthesis and RNA accumulation by mismatched dsRNA. 
  • Inhibition of fetal thymic caspases abrogates the consequences of adenosine deaminase deficiency. 
  • Inhibition of in vitro anti-DNA B-cell responses by cyclosporine. 
  • Initiation of allelic exclusion by stochastic interaction of Tcrb alleles with repressive nuclear compartments. 
  • Innate anti-breast cancer immunity of apoptosis-resistant human gammadelta-T cells. 
  • Innate immune activation potentiates alloimmune lung disease independent of chemokine (C-X-C motif) receptor 3. 
  • Integrase-defective lentiviral-vector-based vaccine: a new vector for induction of T cell immunity. 
  • Interaction of Bordetella pertussis with mast cells, modulation of cytokine secretion by pertussis toxin. 
  • Interaction of pokeweed mitogen with monocytes in the activation of human lymphocytes. 
  • Interactions of innate and adaptive immunity in brain development and function. 
  • Interferon alfa-2a in the treatment of cutaneous T cell lymphoma. 
  • Interleukin-1 stimulates diacylglycerol production in T lymphocytes by a novel mechanism. 
  • Interleukin-21: a multifunctional regulator of immunity to infections. 
  • Interleukin-3 expression by activated T cells involves an inducible, T-cell-specific factor and an octamer binding protein. 
  • Interleukin-7 permits Th1/Tc1 maturation and promotes ex vivo expansion of cord blood T cells: a critical step toward adoptive immunotherapy after cord blood transplantation. 
  • Interpreting low T-cell receptor excision circles in newborns with DiGeorge anomaly: importance of assessing naive T-cell markers. 
  • Intrathecal morphine suppresses immune function in rats with inflammatory-induced pain. 
  • Involvement of linker for activation of T cells in the costimulatory signaling pathways. 
  • Involvement of protein tyrosine phosphorylation in immunotoxin effects on T lymphocytes. 
  • Irradiation and immunotherapy: From concept to the clinic. 
  • Is tolerance induction the answer to adolescent non-adherence? 
  • Isolation and characterization of the genomic human CD7 gene: structural similarity with the murine Thy-1 gene. 
  • Juvenile arthritis and autoimmunity to type II collagen. 
  • K12/SECTM1, an interferon-γ regulated molecule, synergizes with CD28 to costimulate human T cell proliferation. 
  • Keyhole limpet haemocyanin - a model antigen for human immunotoxicological studies. 
  • Kinetics of TCR use in response to repeated epitope-specific immunization. 
  • Kinetics of expression of multiply spliced RNA in early human immunodeficiency virus type 1 infection of lymphocytes and monocytes. 
  • Knock-in mutation of the distal four tyrosines of linker for activation of T cells blocks murine T cell development. 
  • L-selectin and intercellular adhesion molecule 1 mediate lymphocyte migration to the inflamed airway/lung during an allergic inflammatory response in an animal model of asthma. 
  • L-selectin shedding does not regulate constitutive T cell trafficking but controls the migration pathways of antigen-activated T lymphocytes. 
  • LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation. 
  • LKLF: A transcriptional regulator of single-positive T cell quiescence and survival. 
  • Lack of generation of killer cells in the mixed lymphocyte reaction between mitogen-stimulated and unstimulated autologous lymphocytes. 
  • Lenalidomide enhances the function of chimeric antigen receptor T cells against the epidermal growth factor receptor variant III by enhancing immune synapses. 
  • Leprosy in a mangabey monkey--naturally acquired infection. 
  • Leptin receptor is expressed in thymus medulla and leptin protects against thymic remodeling during endotoxemia-induced thymus involution. 
  • Lessons learned from HIV-1 vaccine trials: new priorities and directions. 
  • Leukemias and lymphomas of thymic differentiation. 
  • Leukemic reticuloendotheliosis: presence of a receptor for cytophilic antibody. 
  • Leukocyte composition of human breast cancer. 
  • Leukocyte entry into sites of inflammation requires overlapping interactions between the L-selectin and ICAM-1 pathways. 
  • Leukocyte homing to synovium. 
  • Leukocyte subpopulations in cerebrospinal fluid of normal rabbits. 
  • Lifespan-extending caloric restriction or mTOR inhibition impair adaptive immunity of old mice by distinct mechanisms. 
  • Ligand-independent toll-like receptor signals generated by ectopic overexpression of MyD88 generate local and systemic antitumor immunity. 
  • Linker for activation of B cells: a functional equivalent of a mutant linker for activation of T cells deficient in phospholipase C-gamma1 binding. 
  • Linker for activation of T cells (LAT), a novel immunohistochemical marker for T cells, NK cells, mast cells, and megakaryocytes: evaluation in normal and pathological conditions. 
  • Linking immune responses with fibrosis in allergic eye disease. 
  • Local mutational diversity drives intratumoral immune heterogeneity in non-small cell lung cancer. 
  • Locus-specific somatic hypermutation in germinal centre T cells. 
  • Long term disease-free survival and T cell and antibody responses in women with high-risk Her2+ breast cancer following vaccination against Her2. 
  • Long-distance regulation of fetal V(δ) gene segment TRDV4 by the Tcrd enhancer. 
  • Long-term follow-up of allogeneic marrow transplants in patients with aplastic anemia conditioned by cyclophosphamide combined with antithymocyte globulin. 
  • Long-term in vivo imaging of multiple organs at the single cell level. 
  • Long-term interleukin 10 therapy in chronic hepatitis C patients has a proviral and anti-inflammatory effect. 
  • Long-term outcome of non-ablative booster BMT in patients with SCID. 
  • Lupus nephritis: update on pathogenesis and disease mechanisms. 
  • Ly6Chi monocytes regulate T cell responses in viral hepatitis. 
  • Lymphocyte Galactocerebrosidase Activity by LC-MS/MS for Post-Newborn Screening Evaluation of Krabbe Disease. 
  • Lymphocyte abnormalities in preleukemia--I. Decreased NK activity, anomalous immunoregulatory cell subsets and deficient EBV receptors. 
  • Lymphocyte and monocyte subset changes during cardiopulmonary bypass: effects of aging and gender. 
  • Lymphocyte development and selection in germinal centers. 
  • Lymphocyte subpopulations and responsiveness in rats bearing intracranial tumors induced by avian sarcoma virus. 
  • Lymphocytic leukemia in children: prognostic significance of clinical and laboratory findings at time of diagnosis. 
  • Lymphocytic vasculitis involving the central nervous system occurs in patients with X-linked lymphoproliferative disease in the absence of Epstein-Barr virus infection. 
  • Lymphodepletional strategies in transplantation. 
  • Lymphotoxin alpha/beta and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen. 
  • Lyphocyte migration in L-selectin-deficient mice. Altered subset migration and aging of the immune system. 
  • Lyt phenotype of H-2b CTL effectors and precursors specific for the SV40 transplantation rejection antigen. 
  • MCA106 fibrosarcoma cells transduced with granulocyte/macrophage colony-stimulating factor are not superior to the wild-type cells in suppressing the growth of hepatic metastases. 
  • MHC class I-peptide interactions and TCR recognition. 
  • Maintaining T lymphocyte homeostasis: another duty of autophagy. 
  • Maintenance of T cell specification and differentiation requires recurrent notch receptor-ligand interactions. 
  • Mast cells process bacterial Ags through a phagocytic route for class I MHC presentation to T cells. 
  • Mature T lymphocyte apoptosis--immune regulation in a dynamic and unpredictable antigenic environment. 
  • Maximizing the retention of antigen specific lymphocyte function after cryopreservation. 
  • Mcl-1 promotes survival of thymocytes by inhibition of Bak in a pathway separate from Bcl-2. 
  • Measurement of an adhesion molecule as an indicator of inflammatory disease activity. Up-regulation of the receptor for hyaluronate (CD44) in rheumatoid arthritis. 
  • Measurement of mouse T cell receptor excision circles. 
  • Mechanism of Epstein-Barr virus-induced human B-lymphocyte activation. 
  • Mechanism of deoxyadenosine-induced catabolism of adenine ribonucleotides in adenosine deaminase-inhibited human T lymphoblastoid cells. 
  • Mechanisms of peripheral T cell tolerance. 
  • Mechanisms of tolerance induced by an immunotoxin against CD3 epsilon in a rhesus kidney allograft model. 
  • Memory T cells in organ transplantation: progress and challenges. 
  • Memory T-cell-specific therapeutics in organ transplantation. 
  • Metabolic Barriers to T Cell Function in Tumors. 
  • Metabolic pathways in T cell fate and function. 
  • Metabolic reprogramming is required for antibody production that is suppressed in anergic but exaggerated in chronically BAFF-exposed B cells. 
  • Metabolism and autophagy in the immune system: immunometabolism comes of age. 
  • Metabolites from apoptotic thymocytes inhibit thymopoiesis in adenosine deaminase-deficient fetal thymic organ cultures. 
  • Metastable tolerance in nonhuman primates and humans. 
  • Mice deficient in LRG-47 display increased susceptibility to mycobacterial infection associated with the induction of lymphopenia. 
  • Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization. 
  • Mice lacking expression of the chemokines CCL21-ser and CCL19 (plt mice) demonstrate delayed but enhanced T cell immune responses. 
  • Mice lacking the p53-effector gene Gadd45a develop a lupus-like syndrome. 
  • MicroRNA-17-92 controls T-cell responses in graft-versus-host disease and leukemia relapse in mice. 
  • MicroRNA-34a enhances T cell activation by targeting diacylglycerol kinase ζ. 
  • Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis. 
  • Microparticles stimulate the synthesis of prostaglandin E(2) via induction of cyclooxygenase 2 and microsomal prostaglandin E synthase 1. 
  • Minimal requirement of tyrosine residues of linker for activation of T cells in TCR signaling and thymocyte development. 
  • Mitophagy in the little lymphocytes: an essential role for autophagy in mitochondrial clearance in T lymphocytes. 
  • Mixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanes. 
  • Mobilization of dendritic cells from patients with breast cancer into peripheral blood stem cell leukapheresis samples using Flt-3-Ligand and G-CSF or GM-CSF. 
  • Modeling Sjögren's syndrome with Id3 conditional knockout mice. 
  • Modified LSA2-L2 treatment in 53 children with E-rosette-positive T-cell leukemia: results and prognostic factors (a Pediatric Oncology Group Study). 
  • Modified MHC restriction of donor-origin T cells in humans with severe combined immunodeficiency transplanted with haploidentical bone marrow stem cells. 
  • Modified T-cell receptor ligands: moving beyond a strict occupancy model for T-cell activation by antigen. 
  • Modified responses to recipient and donor B cells by genetically donor T cells from human haploidentical bone marrow chimeras. 
  • Modulating adaptive immune responses to peptide self-assemblies. 
  • Modulation of the intracellular Ca2+ and inositol trisphosphate concentrations in murine T lymphocytes by the glycosylphosphatidylinositol-anchored protein sgp-60. 
  • Molecular and cellular profiling of acute responses to total body radiation exposure in ovariectomized female cynomolgus macaques. 
  • Molecular and immunohistochemical characterization of the onset and resolution of human renal allograft ischemia-reperfusion injury. 
  • Molecular basis of T cell inactivation by CTLA-4. 
  • Molecular identification, cloning and characterization of transmitted/founder HIV-1 subtype A, D and A/D infectious molecular clones. 
  • Molecular measurement of T cell receptor excision circles. 
  • Molecular mechanism of desensitization of the chemokine receptor CCR-5: receptor signaling and internalization are dissociable from its role as an HIV-1 co-receptor. 
  • Monitoring cellular immune responses to cancer immunotherapy. 
  • Monoclonal antibodies against human T cell leukemia-lymphoma virus (HTLV) p24 internal core protein. Use as diagnostic probes and cellular localization of HTLV. 
  • Monoclonal antibodies to CD2 and lymphocyte function-associated antigen 3 inhibit human thymic epithelial cell-dependent mature thymocyte activation. 
  • Monoclonal antibodies to T-helper/inducer and T-suppressor/cytotoxic lymphocyte subsets recognize antigens on splenic sinusoidal lining cells. 
  • Monoclonal antibodies to the common gamma-chain as cytokine receptor antagonists in vivo: effect on intrathymic and intestinal intraepithelial T lymphocyte development. 
  • Monoclonal antibodies to tissue-associated antigens as antitumor reagents. 
  • Monoclonal antibody OKT3-induced T cell proliferation: differential role of HLA class II determinants expressed by T cells and monocytes. 
  • Monoclonal antibody defines human cell surface protein p80 on intrathymic T cells. 
  • Monoclonal antibody definition of T cell acute leukemia: a Pediatric Oncology Group study. 
  • Monocyte infiltration and kidney allograft dysfunction during acute rejection. 
  • Monolayer absorption of human cytotoxic T cells: evidence for clonality. 
  • Mononuclear cells from patients with the hyper-IgE syndrome produce little IgE when they are stimulated with recombinant human interleukin-4. 
  • Mucosal and systemic immune activation is present in human immunodeficiency virus-exposed seronegative women. 
  • Multi-envelope HIV-1 vaccine devoid of SIV components controls disease in macaques challenged with heterologous pathogenic SHIV. 
  • Multiple constraints at the level of TCRalpha rearrangement impact Valpha14i NKT cell development. 
  • Multiple myeloma-associated amyloidosis and giant cell arteritis. 
  • Multiple proteins interact with the nuclear inhibitory protein repressor element in the human interleukin-3 promoter. 
  • Murine CXCR-4 is a functional coreceptor for T-cell-tropic and dual-tropic strains of human immunodeficiency virus type 1. 
  • Murine granulocyte-macrophage colony-stimulating factor expressed from a bicistronic simian immunodeficiency virus-based integrase-defective lentiviral vector does not enhance T-cell responses in mice. 
  • Murine monoclonal anti-T cell antibodies for treatment of steroid-resistant acute graft-versus-host disease. 
  • Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development. 
  • Mutations in genes required for T-cell development: IL7R, CD45, IL2RG, JAK3, RAG1, RAG2, ARTEMIS, and ADA and severe combined immunodeficiency: HuGE review. 
  • NLRP3 inflammasome induces chemotactic immune cell migration to the CNS in experimental autoimmune encephalomyelitis. 
  • NOX2 protects against prolonged inflammation, lung injury, and mortality following systemic insults. 
  • Natural IgM Switches the Function of Lipopolysaccharide-Activated Murine Bone Marrow-Derived Dendritic Cells to a Regulatory Dendritic Cell That Suppresses Innate Inflammation. 
  • Natural killing target antigens as inducers of interferon: studies with an immunoselected, natural killing-resistant human T lymphoblastoid cell line. 
  • Negative regulation of T cell activation and autoimmunity by the transmembrane adaptor protein LAB. 
  • Negative regulation of TCR signaling by linker for activation of X cells via phosphotyrosine-dependent and -independent mechanisms. 
  • Negative regulation of lymphocyte activation by the adaptor protein LAX. 
  • Neonatal chlorpyrifos administration elicits deficits in immune function in adulthood: a neural effect? 
  • Neonates support "homeostatic" proliferation. 
  • Neutralizing BAFF/APRIL with atacicept prevents early DSA formation and AMR development in T cell depletion induced nonhuman primate AMR model. 
  • Neutrophils with myeloid derived suppressor function deplete arginine and constrain T cell function in septic shock patients. 
  • New perspectives on zoledronic acid in breast cancer: potential augmentation of anticancer immune response. 
  • Nicotinamide adenine dinucleotide (NAD) and its metabolites inhibit T lymphocyte proliferation: role of cell surface NAD glycohydrolase and pyrophosphatase activities. 
  • Noncoding transcription controls downstream promoters to regulate T-cell receptor alpha recombination. 
  • Nonmyeloablative regimen preserves "niches" allowing for peripheral expansion of donor T-cells. 
  • Norepinephrine regulates hepatic innate immune system in leptin-deficient mice with nonalcoholic steatohepatitis. 
  • Notch 1 signaling regulates peripheral T cell activation. 
  • Notch promotes survival of pre-T cells at the beta-selection checkpoint by regulating cellular metabolism 
  • Notch signaling is a potent inducer of growth arrest and apoptosis in a wide range of B-cell malignancies. 
  • Notch signalling in B cells. 
  • Notch1 perturbation of hemopoiesis involves non-cell- autonomous modifications. 
  • Novel adenoviral vector induces T-cell responses despite anti-adenoviral neutralizing antibodies in colorectal cancer patients. 
  • Novel interleukin-2 receptor subunit detected by cross-linking under high-affinity conditions. 
  • Novel splicing, missense, and deletion mutations in seven adenosine deaminase-deficient patients with late/delayed onset of combined immunodeficiency disease. Contribution of genotype to phenotype. 
  • Nucleosome in patients with systemic sclerosis: possible association with immunological abnormalities via abnormal activation of T and B cells. 
  • Nutritional effects on T-cell immunometabolism. 
  • Once daily i.v. busulfan and fludarabine (i.v. Bu-Flu) compares favorably with i.v. busulfan and cyclophosphamide (i.v. BuCy2) as pretransplant conditioning therapy in AML/MDS. 
  • Ontogeny of T-cell precursors: a model for the initial stages of human T-cell development. 
  • Ontogeny of the human thymus during fetal development. 
  • Optimizing parallel induction of HIV type 1-specific antibody and T-cell responses by multicomponent subunit vaccines. 
  • Orchestrating T-cell receptor α gene assembly through changes in chromatin structure and organization. 
  • Orchestration of invariant natural killer T cell development by E and Id proteins. 
  • Orientation-specific RAG activity in chromosomal loop domains contributes to Tcrd V(D)J recombination during T cell development. 
  • Orphan nuclear receptors in T lymphocyte development. 
  • Overcoming Chronic Rejection-Can it B? 
  • Overexpression of the Notch target genes Hes in vivo induces lymphoid and myeloid alterations. 
  • PD-1/PD-L1, but not PD-1/PD-L2, interactions regulate the severity of experimental autoimmune encephalomyelitis. 
  • PF4/heparin complexes are T cell-dependent antigens. 
  • PP6 controls T cell development and homeostasis by negatively regulating distal TCR signaling. 
  • Pain regulation by non-neuronal cells and inflammation. 
  • Paired cloning of the T cell receptor alpha and beta genes from a single T cell without the establishment of a T cell clone. 
  • Palmitoylation-dependent plasma membrane transport but lipid raft-independent signaling by linker for activation of T cells. 
  • Paradoxical expression of adenosine deaminase in T cells cultured from a patient with adenosine deaminase deficiency and combine immunodeficiency. 
  • Pathogenicity of simian-human immunodeficiency virus SHIV-89.6P and SIVmac is attenuated in cynomolgus macaques and associated with early T-lymphocyte responses. 
  • Pathophysiologic mechanisms of acute graft-vs.-host disease. 
  • Peptide-conjugated PAMAM dendrimer as a universal DNA vaccine platform to target antigen-presenting cells. 
  • Peptide-major histocompatibility complex class II complexes with mixed agonist/antagonist properties provide evidence for ligand-related differences in T cell receptor-dependent intracellular signaling. 
  • Performance of serum-supplemented and serum-free media in IFNgamma Elispot Assays for human T cells. 
  • Permanent survival of fully MHC-mismatched islet allografts by targeting a single chemokine receptor pathway. 
  • Persistent Toll-like receptor signals are required for reversal of regulatory T cell-mediated CD8 tolerance. 
  • Persistent coinfection of T lymphocytes with HTLV-II and HIV and the role of syncytium formation in HIV-induced cytopathic effect. 
  • Perspective: research highlights at the Duke University center for AIDS research. Immunoreconstitution in HIV infection: the role of the thymus. 
  • Pertussis toxin triggers rapid second messenger production in human T lymphocytes. 
  • Pharmacologic purging of malignant T cells from human bone marrow using 9-beta-D-arabinofuranosylguanine. 
  • Phase 1 Dose Escalation Study of MEDI-565, a Bispecific T-Cell Engager that Targets Human Carcinoembryonic Antigen, in Patients With Advanced Gastrointestinal Adenocarcinomas. 
  • Phase 1 clinical trial of HER2-specific immunotherapy with concomitant HER2 kinase inhibition [corrected]. 
  • Phase 1 gene therapy for Duchenne muscular dystrophy using a translational optimized AAV vector. 
  • Phenotypic and functional characterization of human malignant T cells. 
  • Phenotypic characterization and ontogeny of components of the human thymic microenvironment. 
  • Phenotypic characterization of cutaneous T-cell lymphoma. Use of monoclonal antibodies to compare with other malignant T cells. 
  • Phenotypic characterization of human cytolytic T lymphocytes in mixed lymphocyte culture. 
  • Phenotypic characterization of skin-infiltrating T cells in cutaneous T-cell lymphoma: comparison with benign cutaneous T-cell infiltrates. 
  • Phenotypic variation in the response to the human immunodeficiency virus among derivatives of the CEM T and WIL-2 B cell lines. 
  • Piceatannol in combination with low doses of cyclosporine A prolongs kidney allograft survival in a stringent rat transplantation model. 
  • Pillars Article: Identification of a Putative Second T-cell Receptor. Nature. 1986. 322: 145-149. 
  • Polyclonal immune responses to antigens associated with cancer signaling pathways and new strategies to enhance cancer vaccines. 
  • Polyfunctional T-Cell Signatures to Predict Protection from Cytomegalovirus after Lung Transplantation. 
  • Polyfunctional cytomegalovirus-specific immunity in lung transplant recipients receiving valganciclovir prophylaxis. 
  • Porcine CD80: cloning, characterization, and evidence for its role in direct human T-cell activation. 
  • Positive Family History, Infection, Low Absolute Lymphocyte Count (ALC), and Absent Thymic Shadow: Diagnostic Clues for All Molecular Forms of Severe Combined Immunodeficiency (SCID). 
  • Positive and negative elements regulate human interleukin 3 expression. 
  • Positive and negative regulation of FcepsilonRI-mediated signaling by the adaptor protein LAB/NTAL. 
  • Possible extrathymic development of nonfunctional T cells in a patient with complete DiGeorge syndrome. 
  • Postbinding functions of CD4 in HIV infection. 
  • Posttranslational regulation of TCR Valpha allelic exclusion during T cell differentiation. 
  • Potency of a Scalable Nanoparticulate Subunit Vaccine. 
  • Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference. 
  • Potent, protective anti-HIV immune responses generated by bimodal HIV envelope DNA plus protein vaccination. 
  • Potential To Streamline Heterologous DNA Prime and NYVAC/Protein Boost HIV Vaccine Regimens in Rhesus Macaques by Employing Improved Antigens. 
  • Potentiation of CD3-induced expression of the linker for activation of T cells (LAT) by the calcineurin inhibitors cyclosporin A and FK506. 
  • Pre-T cell receptor's clashing signals: "should I stay or should I go". 
  • Precision cancer immunotherapy: optimizing dendritic cell-based strategies to induce tumor antigen-specific T-cell responses against individual patient tumors. 
  • Preclinical evaluation of ex vivo expanded/activated γδ T cells for immunotherapy of glioblastoma multiforme. 
  • Preclinical studies of human immunodeficiency virus/AIDS vaccines: inverse correlation between avidity of anti-Env antibodies and peak postchallenge viremia. 
  • Prediction of T-cell reconstitution by assessment of T-cell receptor excision circle before allogeneic hematopoietic stem cell transplantation in pediatric patients. 
  • Prednisone-responsive aplastic anemia associated with T-lymphocyte proliferation. 
  • Preexisting compensatory amino acids compromise fitness costs of a HIV-1 T cell escape mutation. 
  • Premature T Cell Senescence in Pediatric CKD. 
  • Prenatal test for X-linked severe combined immunodeficiency by analysis of maternal X-chromosome inactivation and linkage analysis. 
  • Preoperative mobilization of circulating dendritic cells by Flt3 ligand administration to patients with metastatic colon cancer. 
  • Preparation and characterization of an intravenous solution of IgG from human immunodeficiency virus-seropositive donors. 
  • Pretreatment cytokinetic studies in 94 children with acute leukemia. Relationship to other variables at diagnosis and to outcome of standard treatment. 
  • Prevention and treatment of graft-versus-host disease. 
  • Prevention of GVHD without losing GVL effect: windows of opportunity. 
  • Prevention of autoimmune islet allograft destruction by engraftment of donor T cells. 
  • Prevention of graft-versus-host disease by a novel immunosuppressant, PG490-88, through inhibition of alloreactive T cell expansion. 
  • Prevention of graft-versus-host disease by peptides binding to class II major histocompatibility complex molecules. 
  • Prevention of graft-versus-host disease while preserving graft-versus-leukemia effect after selective depletion of host-reactive T cells by photodynamic cell purging process. 
  • Primary cellular immunodeficiencies. 
  • Primary intraocular T-cell-rich large B-cell lymphoma. 
  • Priming, boosting, measuring. 
  • Production and role of cytokines in the CNS of mice with acute viral encephalomyelitis. 
  • Profiling of CD4+, CD8+, and CD4+CD25+CD45RO+FoxP3+ T cells in patients with malignant glioma reveals differential expression of the immunologic transcriptome compared with T cells from healthy volunteers. 
  • Progesterone inhibits glucocorticoid-induced murine thymocyte apoptosis. 
  • Programming the magnitude and persistence of antibody responses with innate immunity 
  • Progress in graft-versus-host disease. 
  • Proinflammatory actions of thromboxane receptors to enhance cellular immune responses. 
  • Proline isomerases at the crossroads of protein folding, signal transduction, and immunosuppression. 
  • Prolonged discordant xenograft survival and delayed xenograft rejection in a pig-to-baboon orthotopic cardiac xenograft model. 
  • Prominent expression of mRNA for proinflammatory cytokines in synovium in patients with juvenile rheumatoid arthritis or chronic Lyme arthritis. 
  • Protection against malaria at 1 year and immune correlates following PfSPZ vaccination. 
  • Protection of macaques against intrarectal infection by a combination immunization regimen with recombinant simian immunodeficiency virus SIVmne gp160 vaccines. 
  • Protective immunosurveillance and therapeutic antitumor activity of gammadelta T cells demonstrated in a mouse model of prostate cancer. 
  • Proteomics for monitoring immune responses to cancer vaccines. 
  • Purification, characterization, and structural elucidation of the active moiety of the previously called "suppressor activating factor (SAF)". 
  • Purified lymphocyte function-associated antigen-3 (LFA-3) activates human thymocytes via the CD2 pathway. 
  • Purine nucleoside phosphorylase deficiency. 
  • Quality control in the flow cytometric measurement of T-lymphocyte subsets: the multicenter AIDS cohort study experience. The Multicenter AIDS Cohort Study Group. 
  • Quantitating therapeutically relevant T-cell responses to cancer vaccines. 
  • Quantitative and qualitative differences in the T cell response to HIV in uninfected ugandans exposed or unexposed to HIV-infected partners 
  • Quiescent phenotype of tumor-specific CD8+ T cells following immunization. 
  • RIP1-dependent and independent effects of necrostatin-1 in necrosis and T cell activation. 
  • RORgamma t, a novel isoform of an orphan receptor, negatively regulates Fas ligand expression and IL-2 production in T cells. 
  • Rabbit antithymocyte globulin decreases acute rejection after lung transplantation: results of a randomized, prospective study. 
  • Race-related differences in antibody responses to the inactivated influenza vaccine are linked to distinct pre-vaccination gene expression profiles in blood. 
  • Radiation and a metalloporphyrin radioprotectant in a mouse prostate tumor model. 
  • Radiation combined with thermal injury induces immature myeloid cells. 
  • Randomized, double-blind, Phase 1 trial of an alphavirus replicon vaccine for cytomegalovirus in CMV seronegative adult volunteers. 
  • Rapamycin antagonizes cyclosporin A- and tacrolimus (FK506)-mediated augmentation of linker for activation of T cell expression in T cells. 
  • Rapid SIV Env-specific mucosal and serum antibody induction augments cellular immunity in protecting immunized, elite-controller macaques against high dose heterologous SIV challenge. 
  • Rapid and specific conversion of precursor interleukin 1 beta (IL-1 beta) to an active IL-1 species by human mast cell chymase. 
  • Rapid serologic diagnosis of serum sickness from antithymocyte globulin therapy using enzyme immunoassay. 
  • Recent advances in immunosuppressive therapy for prevention of renal allograft rejection. 
  • Recent areas of development for dendritic cell vaccines. 
  • Receptor signaling in immune cell development and function. 
  • Receptor-mediated antigen delivery into macrophages. Complexing antigen to alpha 2-macroglobulin enhances presentation to T cells. 
  • Receptors for prostaglandin E(2) that regulate cellular immune responses in the mouse. 
  • Recipient Myd88 Deficiency Promotes Spontaneous Resolution of Kidney Allograft Rejection. 
  • Recognition and killing of autologous, primary glioblastoma tumor cells by human cytomegalovirus pp65-specific cytotoxic T cells. 
  • Recognition of glioma stem cells by genetically modified T cells targeting EGFRvIII and development of adoptive cell therapy for glioma. 
  • Recollective homeostasis and the immune consequences of peritransplant depletional induction therapy. 
  • Recombinant Mycobacterium bovis BCG prime-recombinant adenovirus boost vaccination in rhesus monkeys elicits robust polyfunctional simian immunodeficiency virus-specific T-cell responses. 
  • Recombinant Mycobacterium bovis bacillus Calmette-Guerin elicits human immunodeficiency virus type 1 envelope-specific T lymphocytes at mucosal sites. 
  • Recombinant human IL-4 induces IgE and IgG synthesis by normal and atopic donor mononuclear cells. Similar dose response, time course, requirement for T cells, and effect of pokeweed mitogen. 
  • Recombinant human interleukin 1 alpha: purification and biological characterization. 
  • Recombinant hydrophilic region of murine retroviral protein p15E inhibits stimulated T-lymphocyte proliferation. 
  • Recombinant modified vaccinia virus Ankara provides durable protection against disease caused by an immunodeficiency virus as well as long-term immunity to an orthopoxvirus in a non-human primate. 
  • Recombinant poxvirus boosting of DNA-primed rhesus monkeys augments peak but not memory T lymphocyte responses. 
  • Reconstitution of a T cell receptor-stimulated plasma membrane calcium transporter: lack of dependence on inositol phosphates. 
  • Reconstitution of high affinity IL-2 receptor expression in a human T-cell line using a retroviral cDNA expression vector. 
  • Recruitment of Donor T Cells to the Eyes During Ocular GVHD in Recipients of MHC-Matched Allogeneic Hematopoietic Stem Cell Transplants. 
  • Redirecting migration of T cells to chemokine secreted from tumors by genetic modification with CXCR2. 
  • Reduced thymic maturation but normal effector function of CD8+ T cells in CD8 beta gene-targeted mice. 
  • Reduced-intensity conditioning using fludarabine, melphalan and thiotepa for adult patients undergoing haploidentical SCT. 
  • Regression of human kidney cancer following allogeneic stem cell transplantation is associated with recognition of an HERV-E antigen by T cells. 
  • Regulated protein denitrosylation by cytosolic and mitochondrial thioredoxins. 
  • Regulating T Cell Behavior. 
  • Regulation and properties of the rat Ca2+/calmodulin-dependent protein kinase IV gene and its protein products. 
  • Regulation of RasGRP1 function in T cell development and activation by its unique tail domain. 
  • Regulation of T cell receptor alpha gene assembly by a complex hierarchy of germline Jalpha promoters. 
  • Regulation of T cell receptor- and CD28-induced tyrosine phosphorylation of the focal adhesion tyrosine kinases Pyk2 and Fak by protein kinase C. A role for protein tyrosine phosphatases. 
  • Regulation of T-cell survival and mitochondrial homeostasis by TSC1. 
  • Regulation of cAMP and cGMP signaling: new phosphodiesterases and new functions. 
  • Regulation of early lymphocyte development by E2A family proteins. 
  • Regulation of human immunodeficiency virus replication. 
  • Regulation of leukocyte migration by activation of the leukocyte adhesion molecule-1 (LAM-1) selectin. 
  • Regulation of local and metastatic host-mediated anti-tumour mechanisms by L-selectin and intercellular adhesion molecule-1. 
  • Regulation of nuclear Prointerleukin-16 and p27(Kip1) in primary human T lymphocytes. 
  • Regulation of the B cell response to T-dependent antigens by classical pathway complement. 
  • Regulation of the human interleukin-3 gene. 
  • Regulation of the immune response. I. Regulatory cell equilibrium in the "virgin" state. 
  • Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions. 
  • Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progression. 
  • Regulatory B10 cell development and function. 
  • Relatedness by nucleic acid hybridization of new isolates of human T-cell leukemia-lymphoma virus (HTLV) and demonstration of provirus in uncultured leukemic blood cells. 
  • Relationships among renal allograft biopsy infiltrates, growth of T cell lines, and irreversible rejection. 
  • Renal allograft cell infiltrates associated with irreversible rejection. 
  • Renal effects of cytokines in hypertension. 
  • Renal epithelial cells produce and spread HIV-1 via T-cell contact. 
  • Replicating adenovirus HIV/SIV recombinant priming alone or in combination with a gp140 protein boost results in significant control of viremia following a SHIV89.6P challenge in Mamu-A*01 negative rhesus macaques. 
  • Replicating adenovirus-simian immunodeficiency virus (SIV) recombinant priming and envelope protein boosting elicits localized, mucosal IgA immunity in rhesus macaques correlated with delayed acquisition following a repeated low-dose rectal SIV(mac251) challenge. 
  • Requirement for Ca2+/calmodulin-dependent kinase type IV/Gr in setting the thymocyte selection threshold. 
  • Requirement of the Src homology 2 domain protein Shb for T cell receptor-dependent activation of the interleukin-2 gene nuclear factor for activation of T cells element in Jurkat T cells. 
  • Requirements for T lymphocyte migration in explanted lymph nodes. 
  • Response and toxicity of donor lymphocyte infusions following T-cell depleted non-myeloablative allogeneic hematopoietic SCT from 3-6/6 HLA matched donors. 
  • Results from a human renal allograft tolerance trial evaluating T-cell depletion with alemtuzumab combined with deoxyspergualin. 
  • Results from a human renal allograft tolerance trial evaluating the humanized CD52-specific monoclonal antibody alemtuzumab (CAMPATH-1H). 
  • Retinal pigment epithelial cells induce foxp3(+) regulatory T cells via membrane-bound TGF-β. 
  • Retinoid-related orphan receptor gamma (RORgamma) is essential for lymphoid organogenesis and controls apoptosis during thymopoiesis. 
  • Retrovirus-elicited interleukin-12 and tumour necrosis factor-alpha as inducers of interferon-gamma-mediated pathology in mouse AIDS. 
  • Retroviruses and human cancer: evaluation of T-lymphocyte transformation by human T-cell leukemia-lymphoma virus. 
  • Reversal of acute allograft rejection using immunotoxin. 
  • Review of 54 patients with complete DiGeorge anomaly enrolled in protocols for thymus transplantation: outcome of 44 consecutive transplants. 
  • Rhbdd3 controls autoimmunity by suppressing the production of IL-6 by dendritic cells via K27-linked ubiquitination of the regulator NEMO. 
  • Rheumatoid arthritis and sterile corneal ulceration. Analysis of tissue immune effector cells and ocular epithelial antigens using monoclonal antibodies. 
  • Rho kinase promotes alloimmune responses by regulating the proliferation and structure of T cells. 
  • Risk of lymphoproliferative disorders after bone marrow transplantation: a multi-institutional study. 
  • Role for the Abi/wave protein complex in T cell receptor-mediated proliferation and cytoskeletal remodeling. 
  • Role of C-C motif ligand 2 and C-C motif receptor 2 in murine pulmonary graft-versus-host disease after lipopolysaccharide inhalations. 
  • Role of T cell recruitment and chemokine-regulated intra-graft T cell motility patterns in corneal allograft rejection. 
  • Role of T lymphocytes in hypertension. 
  • Role of Toll-like receptor-driven innate immunity in thoracic organ transplantation. 
  • Role of calcium in T-lymphocyte activation. 
  • Role of diacylglycerol kinases in T cell development and function. 
  • Role of folylpolyglutamates in biochemical modulation of fluoropyrimidines by leucovorin. 
  • Role of human immunodeficiency virus (HIV) type 1 envelope in the anti-HIV activity of the betulinic acid derivative IC9564. 
  • Role of interleukin 12 and costimulators in T cell anergy in vivo. 
  • Roles of autophagy in lymphocytes: reflections and directions. 
  • S-Nitrosoglutathione Reductase Deficiency Confers Improved Survival and Neurological Outcome in Experimental Cerebral Malaria. 
  • SLE nephritis is associated with an oligoclonal expansion of intrarenal T cells. 
  • STK11/LKB1 Deficiency Promotes Neutrophil Recruitment and Proinflammatory Cytokine Production to Suppress T-cell Activity in the Lung Tumor Microenvironment. 
  • Safety and immunogenicity of a candidate HIV-1 vaccine in healthy adults: recombinant glycoprotein (rgp) 120. A randomized, double-blind trial. NIAID AIDS Vaccine Evaluation Group. 
  • Safety and immunogenicity of a live recombinant canarypox virus expressing HIV type 1 gp120 MN MN tm/gag/protease LAI (ALVAC-HIV, vCP205) followed by a p24E-V3 MN synthetic peptide (CLTB-36) administered in healthy volunteers at low risk for HIV infection. AGIS Group and L'Agence Nationale de Recherches sur Le Sida. 
  • Safety and immunogenicity of a replication-defective adenovirus type 5 HIV vaccine in Ad5-seronegative persons: a randomized clinical trial (HVTN 054). 
  • Safety and immunogenicity of recombinant poxvirus HIV-1 vaccines in young adults on highly active antiretroviral therapy. 
  • Salmonella disrupts lymph node architecture by TLR4-mediated suppression of homeostatic chemokines. 
  • Screening of HIV-1 Env glycoproteins for the ability to raise neutralizing antibody using DNA immunization and recombinant vaccinia virus boosting. 
  • Second malignancies in cutaneous T cell lymphoma. 
  • Secondary acute myeloid leukemia in children treated for acute lymphoid leukemia. 
  • Secondary allergic T cell responses are regulated by dendritic cell-derived thrombospondin-1 in the setting of allergic eye disease. 
  • Secondary cancers after bone marrow transplantation for leukemia or aplastic anemia. 
  • Selection of stem cells by using antibodies that target different CD34 epitopes yields different patterns of T-cell differentiation. 
  • Selective Targeting of High-Affinity LFA-1 Does Not Augment Costimulation Blockade in a Nonhuman Primate Renal Transplantation Model. 
  • Selective antiviral activity of synthetic soluble L-tyrosine and L-dopa melanins against human immunodeficiency virus in vitro. 
  • Selective costimulation modulation with abatacept: a look at quality-of-life outcomes in patients with rheumatoid arthritis. 
  • Selective elimination of alloreactivity from immunotherapeutic T cells by photodynamic cell purging and memory T-cell sorting. 
  • Selective modification of antigen-specific T cells by RNA electroporation. 
  • Selective targeting of human alloresponsive CD8+ effector memory T cells based on CD2 expression. 
  • Self-assembled peptide nanofibers raising durable antibody responses against a malaria epitope. 
  • Senescent phenotypes and telomere lengths of peripheral blood T-cells mobilized by acute exercise in humans. 
  • Sequential delivery of maturation stimuli increases human dendritic cell IL-12 production and enhances tumor antigen-specific immunogenicity. 
  • Sequential immunotherapy by vaccination with GM-CSF-expressing glioma cells and CTLA-4 blockade effectively treats established murine intracranial tumors. 
  • Serial measurement of serum interleukin-2 receptor levels in patients with rheumatoid arthritis: limited evidence for a role of T cell activation in clinical exacerbations. 
  • Serum sickness and haematopoietic recovery with antithymocyte globulin in bone marrow failure patients. 
  • Severe combined immunodeficiency with natural killer-cell predominance: abrogation of graft-versus-host disease and immunologic reconstitution with HLA-identical bone marrow cells. 
  • Shared and restricted T-cell receptor use is crucial for carbamazepine-induced Stevens-Johnson syndrome. 
  • Shear flow-dependent integration of apical and subendothelial chemokines in T-cell transmigration: implications for locomotion and the multistep paradigm. 
  • Short course induction immunosuppression with thymoglobulin for renal transplant recipients. 
  • Short-term adolescent nicotine exposure in rats elicits immediate and delayed deficits in T-lymphocyte function: critical periods, patterns of exposure, dose thresholds. 
  • Signaling by the TNF receptor superfamily and T cell homeostasis. 
  • Signaling via LAT (linker for T-cell activation) and Syk/ZAP70 is required for ERK activation and NFAT transcriptional activation following CD2 stimulation. 
  • Signature for long-term vaccine-mediated control of a Simian and human immunodeficiency virus 89.6P challenge: stable low-breadth and low-frequency T-cell response capable of coproducing gamma interferon and interleukin-2. 
  • Signatures associated with rejection or recurrence in HER-2/neu-positive mammary tumors. 
  • Significance of regional draining lymph nodes in the development of tumor immunity: implications for cancer immunotherapy. 
  • Similar T-cell immune responses induced by group M consensus env immunogens with wild-type or minimum consensus variable regions. 
  • Sites of B-cell activation in vivo. 
  • Skewing of the population balance of lymphoid and myeloid cells by secreted and intracellular osteopontin. 
  • Skin-resident T cells sense ultraviolet radiation-induced injury and contribute to DNA repair. 
  • SnapShot: Immunometabolism. 
  • Soluble B7-H1: Differences in production between dendritic cells and T cells 
  • Some characteristics of mouse immune (y) interferon produced by a T-lymphoma cell line. 
  • Spatial and temporal dynamics of T cell receptor signaling with a photoactivatable agonist. 
  • Specificity and 6-month durability of immune responses induced by DNA and recombinant modified vaccinia Ankara vaccines expressing HIV-1 virus-like particles. 
  • Spermine dialdehyde, a novel ex vivo purging agent for both allogenic and autologous bone marrow transplantations. 
  • Split tolerance induced by immunotoxin in a rhesus kidney allograft model. 
  • Stable Expression of Lentiviral Antigens by Quality-Controlled Recombinant Mycobacterium bovis BCG Vectors. 
  • Stable expression of transdominant Rev protein in human T cells inhibits human immunodeficiency virus replication. 
  • Stage-specific adhesion molecules in human intrathymic T-cell development. 
  • Stage-specific and differential notch dependency at the alphabeta and gammadelta T lineage bifurcation. 
  • Stage-specific functions of E-proteins at the β-selection and T-cell receptor checkpoints during thymocyte development. 
  • Stem cell transplantation for the treatment of Fanconi anaemia using a fludarabine-based cytoreductive regimen and T-cell-depleted related HLA-mismatched peripheral blood stem cell grafts. 
  • Stimulation of lymphocyte responses by angiotensin II promotes kidney injury in hypertension. 
  • Stimulation of the T3-T cell receptor complex induces a membrane-potential-sensitive calcium influx. 
  • Stimulation of the T3-T cell receptor-associated Ca2+ influx enhances the activity of the Na+/H+ exchanger in a leukemic human T cell line. 
  • Stimulation of thymocyte proliferation by phosphorothioate DNA oligonucleotides. 
  • Stoichiometry of the T cell antigen receptor (TCR) complex: each TCR/CD3 complex contains one TCR alpha, one TCR beta, and two CD3 epsilon chains. 
  • Structural and functional features of the HIV envelope glycoprotein and considerations for vaccine development. 
  • Structurally divergent human T cell receptor gamma proteins encoded by distinct C gamma genes. 
  • Studies investigating pretransplant donor-specific blood transfusion, rapamycin, and the CD154-specific antibody IDEC-131 in a nonhuman primate model of skin allotransplantation. 
  • Studies of T-lymphocytes in preleukemic disorders and acute nonlymphocytic leukemia: in vitro radiosensitivity, mitogenic responsiveness, colony formation, and enumeration of lymphocytic subpopulations. 
  • Studies of human bone marrow treated with soybean lectin and sheep erythrocytes: stepwise analysis of cell morphology, phenotype and function. 
  • Studies of tumor-infiltrating lymphocytes from a human choroidal melanoma. 
  • Studies on GM-CSF DNA as an adjuvant for neutralizing Ab elicited by a DNA/MVA immunodeficiency virus vaccine. 
  • Studies on the adapter molecule LAT. 
  • Subcutaneous vaccination with irradiated, cytokine-producing tumor cells stimulates CD8+ cell-mediated immunity against tumors located in the "immunologically privileged" central nervous system. 
  • Sublethal Total Body Irradiation Causes Long-Term Deficits in Thymus Function by Reducing Lymphoid Progenitors. 
  • Substance P and adrenocorticotropic hormone do not affect T-lymphocyte adhesion to vascular endothelium or surface expression of adhesion receptors. 
  • Successful engraftment of human postnatal thymus in severe combined immune deficient (SCID) mice: differential engraftment of thymic components with irradiation versus anti-asialo GM-1 immunosuppressive regimens. 
  • Suppression of FIP200 and autophagy by tumor-derived lactate promotes naïve T cell apoptosis and affects tumor immunity. 
  • Suppression of Glut1 and Glucose Metabolism by Decreased Akt/mTORC1 Signaling Drives T Cell Impairment in B Cell Leukemia. 
  • Suppression of hepatic allograft rejection in the rat by mitomycin C-treated donor splenocytes: analysis of the immune status. 
  • Suppression of human interferon-gamma production by a 17 amino acid peptide homologous to the transmembrane envelope protein of retroviruses: evidence for a primary role played by monocytes. 
  • Supramolecular peptide vaccines: tuning adaptive immunity. 
  • Surfactant protein A integrates activation signal strength to differentially modulate T cell proliferation. 
  • Surrogate markers of response to cancer immunotherapy. 
  • Syn-capping of human T lymphocyte adhesion/activation molecules and their redistribution during interaction with endothelial cells. 
  • Synergistic control of T cell development and tumor suppression by diacylglycerol kinase alpha and zeta. 
  • Synovial microenvironment-T cell interactions. Human T cells bind to fibroblast-like synovial cells in vitro. 
  • Synthetic peptides containing T and B cell epitopes from human immunodeficiency virus envelope gp120 induce anti-HIV proliferative responses and high titers of neutralizing antibodies in rhesus monkeys. 
  • Systemic administration of a bispecific antibody targeting EGFRvIII successfully treats intracerebral glioma. 
  • Systemic adoptive T-cell immunotherapy in recurrent and metastatic carcinoma of the head and neck: a phase 1 study. 
  • Systemic anti-CD25 monoclonal antibody administration safely enhances immunity in murine glioma without eliminating regulatory T cells. 
  • Systemic surfaceome profiling identifies target antigens for immune-based therapy in subtypes of advanced prostate cancer. 
  • T cell CD7 mRNA expression is regulated by both transcriptional and post-transcriptional mechanisms. 
  • T cell activation deficiency associated with an aberrant pattern of protein tyrosine phosphorylation after CD3 perturbation in Down's syndrome. 
  • T cell activation up-regulates the expression of the focal adhesion kinase Pyk2: opposing roles for the activation of protein kinase C and the increase in intracellular Ca2+. 
  • T cell activation within different intraocular compartments during experimental uveitis. 
  • T cell assays and MIATA: the essential minimum for maximum impact. 
  • T cell depletion increases susceptibility to murine cytomegalovirus retinitis. 
  • T cell development: better living through chromatin. 
  • T cell homeostasis requires G protein-coupled receptor-mediated access to trophic signals that promote growth and inhibit chemotaxis. 
  • T cell immunity in neonates. 
  • T cell inactivation by poxviral B22 family proteins increases viral virulence. 
  • T cell metabolic fitness in antitumor immunity. 
  • T cell receptor binding kinetics and special role of Valpha in T cell development and activation. 
  • T cell receptor excision circle assessment of thymopoiesis in aging mice. 
  • T cell receptor gamma/delta expression on lymphocyte populations of breast cancer patients. 
  • T cell receptor-dependent activation of human lymphocytes through cell surface ganglioside GT1b: implications for innate immunity. 
  • T cell subpopulations in CLL: methods of T cell enrichment artificially alter proportions of OKT4 and OKT8 positive cells. 
  • T cell-mediated elimination of B7.2 transgenic B cells. 
  • T cells and B cells in lupus nephritis. 
  • T cells and T-cell subsets in a large population of patients with primary immunodeficiency. 
  • T cells and macrophages responding to oxidative damage cooperate in pathogenesis of a mouse model of age-related macular degeneration. 
  • T cells as a self-referential, sensory organ. 
  • T cells down-regulate macrophage TNF production by IRAK1-mediated IL-10 expression and control innate hyperinflammation. 
  • T cells or active Epstein-Barr virus infection in the development of lymphoproliferative disease in human B cell-injected severe combined immunodeficient mice. 
  • T lymphocyte depletion of human peripheral blood and bone marrow using monoclonal antibodies and magnetic microspheres. 
  • T lymphocyte ontogeny in adenosine deaminase-deficient severe combined immune deficiency after treatment with polyethylene glycol-modified adenosine deaminase. 
  • T lymphocytes with a normal ADA gene accumulate after transplantation of transduced autologous umbilical cord blood CD34+ cells in ADA-deficient SCID neonates. 
  • T-B+NK+ severe combined immunodeficiency caused by complete deficiency of the CD3zeta subunit of the T-cell antigen receptor complex. 
  • T-Cell recovery in adults and children following umbilical cord blood transplantation. 
  • T-cell clonal change after allo-kidney transplantation in humans. 
  • T-cell development of resistance to apoptosis is driven by a metabolic shift in carbon source and altered activation of death pathways. 
  • T-cell exhaustion: characteristics, causes and conversion. 
  • T-cell lines from 2 patients with adenosine deaminase (ADA) deficiency showed the restoration of ADA activity resulted from the reversion of an inherited mutation. 
  • T-cell receptor α enhancer is inactivated in αβ T lymphocytes. 
  • T-cell vaccine strategies for human immunodeficiency virus, the virus with a thousand faces. 
  • T-cell-directed cancer vaccines: mechanisms of immune escape and immune tolerance. 
  • T-cell-directed cancer vaccines: the melanoma model. 
  • T-cell-independent stimulation of immunoglobulin secretion in resting human B lymphocytes by the mannose-specific adhesin of Escherichia coli type 1 fimbriae. 
  • T-cell-mediated pure red-cell aplasia in systemic lupus erythematosus: response to cyclosporin A and mycophenolate mofetil. 
  • T-cell-receptor affinity and thymocyte positive selection. 
  • T-lymphocyte CREB as a potential biomarker of response to antidepressant drugs. 
  • T-lymphocyte alloresponses of Campath-1H-treated kidney transplant patients. 
  • T3 glycoprotein is functional although structurally distinct on human T-cell receptor gamma T lymphocytes. 
  • TCR alpha-CD3 delta epsilon association is the initial step in alpha beta dimer formation in murine T cells and is limiting in immature CD4+ CD8+ thymocytes. 
  • Targeting HIV-1 Env gp140 to LOX-1 Elicits Immune Responses in Rhesus Macaques. 
  • Targeting the local tumor microenvironment with vaccinia virus expressing B7.1 for the treatment of melanoma. 
  • Tcra gene recombination is supported by a Tcra enhancer- and CTCF-dependent chromatin hub. 
  • Temporal and lineage-specific control of T cell receptor alpha/delta gene rearrangement by T cell receptor alpha and delta enhancers. 
  • Temporal regulation of intracellular organelle homeostasis in T lymphocytes by autophagy. 
  • The "dispensable" portion of RAG2 is necessary for efficient V-to-DJ rearrangement during B and T cell development. 
  • The 5' non-coding region of the BCR/ABL oncogene augments its ability to stimulate the growth of immature lymphoid cells. 
  • The Art and Science of Immunosuppression: the Fifth Annual American Society of Transplant Surgeon's State-of-the-Art Winter Symposium. 
  • The BB diabetic rat. Profound T-cell lymphocytopenia. 
  • The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival. 
  • The CC chemokine thymus-derived chemotactic agent 4 (TCA-4, secondary lymphoid tissue chemokine, 6Ckine, exodus-2) triggers lymphocyte function-associated antigen 1-mediated arrest of rolling T lymphocytes in peripheral lymph node high endothelial venules. 
  • The DNA damage- and transcription-associated protein paxip1 controls thymocyte development and emigration. 
  • The DRiP hypothesis decennial: support, controversy, refinement and extension. 
  • The French-American-British (FAB) classification of leukemia. The Pediatric Oncology Group experience with lymphocytic leukemia. 
  • The HB-6, CDw75, and CD76 differentiation antigens are unique cell-surface carbohydrate determinants generated by the beta-galactoside alpha 2,6-sialyltransferase. 
  • The HIV cytopathic effect: potential target for therapy? 
  • The Knife's Edge of Tolerance: Inducing Stable Multilineage Mixed Chimerism but With a Significant Risk of CMV Reactivation and Disease in Rhesus Macaques. 
  • The allo- and viral-specific immunosuppressive effect of belatacept, but not tacrolimus, attenuates with progressive T cell maturation. 
  • The allure and peril of hematopoietic stem cell transplantation: overcoming immune challenges to improve success. 
  • The anti-apoptotic Bcl-2 family member Mcl-1 promotes T lymphocyte survival at multiple stages. 
  • The antigenic properties of bacterial DNA in normal and aberrant immunity. 
  • The association between immunodeficiency and the development of autoimmune disease. 
  • The binding site of human adenosine deaminase for CD26/Dipeptidyl peptidase IV: the Arg142Gln mutation impairs binding to cd26 but does not cause immune deficiency. 
  • The c-FLIPL cleavage product p43FLIP promotes activation of extracellular signal-regulated kinase (ERK), nuclear factor κB (NF-κB), and caspase-8 and T cell survival. 
  • The canine MHC class Ia allele DLA-88*508:01 presents diverse self- and canine distemper virus-origin peptides of varying length that have a conserved binding motif. 
  • The common gamma-chain of cytokine receptors regulates intrathymic T cell development at multiple stages. 
  • The contribution of autophagy to lymphocyte survival and homeostasis. 
  • The cytolytic molecules Fas ligand and TRAIL are required for murine thymic graft-versus-host disease. 
  • The development and function of regulatory B cells expressing IL-10 (B10 cells) requires antigen receptor diversity and TLR signals. 
  • The differential effect of in vivo hydrocortisone on the kinetics of subpopulations of human peripheral blood thymus-derived lymphocytes. 
  • The dynamics of T-cell receptor repertoire diversity following thymus transplantation for DiGeorge anomaly. 
  • The effect of anti-VEGF therapy on immature myeloid cell and dendritic cells in cancer patients. 
  • The effects of leukemosuppressive immunotherapy on bone marrow infectious cell centers in AKR mice. 
  • The effects of leukemosuppressive immunotherapy on thymic infectious cell centers in AKR mice. 
  • The effects of nonsteroidal antiinflammatory drug therapy in early rheumatoid arthritis on serum levels of soluble interleukin 2 receptor, CD4, and CD8. 
  • The eye: A window to the soul of the immune system. 
  • The fine specificity of human T cell lines towards myelin basic protein peptides in southern Italian multiple sclerosis patients. 
  • The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection. 
  • The functions and measurement of human B- and T-lymphocytes. 
  • The future of organ and tissue transplantation: can T-cell costimulatory pathway modifiers revolutionize the prevention of graft rejection? 
  • The future of rheumatoid arthritis treatment. 
  • The gamma delta T cell receptor. 
  • The germinal center: a crucible for lymphocyte selection. 
  • The helix-loop-helix gene E2A is required for B cell formation. 
  • The human antiporcine cellular repertoire. In vitro studies of acquired and innate cellular responsiveness. 
  • The human thymic microenvironment during organ culture. 
  • The human thymic microenvironment. 
  • The human thymus. A chimeric organ comprised of central and peripheral lymphoid components. 
  • The human thymus. A chimeric organ comprised of central and peripheral lymphoid components. 
  • The immune response to staphylococcal nuclease: a probe of cellular and humoral antigen-specific receptors. 
  • The immune system in aging: roles of cytokines, T cells and NK cells. 
  • The immunologic approach to analysis of malignant lymphoma. Mantle zone lymphoma of the ileocecal region. 
  • The impact of duration versus extent of TCR occupancy on T cell activation: a revision of the kinetic proofreading model. 
  • The importance of LAT in the activation, homeostasis, and regulatory function of T cells. 
  • The importance of Src homology 2 domain-containing leukocyte phosphoprotein of 76 kilodaltons sterile-alpha motif domain in thymic selection and T-cell activation. 
  • The in vivo balance between B cell clonal expansion and elimination is regulated by CD95 both on B cells and in their micro-environment. 
  • The induction of matrix metalloproteinase and cytokine expression in synovial fibroblasts stimulated with immune cell microparticles. 
  • The influence of base sequence on the immunological properties of defined oligonucleotides. 
  • The linker for activation of B cells (LAB)/non-T cell activation linker (NTAL) regulates triggering receptor expressed on myeloid cells (TREM)-2 signaling and macrophage inflammatory responses independently of the linker for activation of T cells. 
  • The liver kinase B1 is a central regulator of T cell development, activation, and metabolism. 
  • The long and the short of telomeres in bone marrow recipient SCID patients. 
  • The long isoform of cellular FLIP is essential for T lymphocyte proliferation through an NF-kappaB-independent pathway. 
  • The long quest for neonatal screening for severe combined immunodeficiency. 
  • The metabolic life and times of a T-cell. 
  • The molecular basis of class II MHC allelic control of T cell responses. 
  • The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity. 
  • The n-hexane and chloroform fractions of Piper betle L. trigger different arms of immune responses in BALB/c mice and exhibit antifilarial activity against human lymphatic filarid Brugia malayi. 
  • The nephritogenic immune response. 
  • The pathophysiology and treatment of graft-versus-host disease. 
  • The perforin-dependent immunological synapse allows T-cell activation-dependent tumor targeting by MLV vector particles. 
  • The persistence of lymphocytes with dicentric chromosomes following whole-body X irradiation of mice. 
  • The role and regulation of mTOR in T-lymphocyte function. 
  • The role of CD4-Lck in T-cell receptor antagonism: evidence for negative signaling. 
  • The role of LAT-PLCγ1 interaction in γδ T cell development and homeostasis. 
  • The role of Nef in the replication cycle of the human and simian immunodeficiency viruses. 
  • The role of Ras guanine nucleotide releasing protein 4 in Fc epsilonRI-mediated signaling, mast cell function, and T cell development. 
  • The role of adhesion molecules in epithelial-T-cell interactions in thymus and skin. 
  • The role of apoptosis in the development and function of T lymphocytes. 
  • The role of complement in the induction of antibody responses. 
  • The role of leukocyte adhesion molecules in cellular interactions: implications for the pathogenesis of inflammatory synovitis. 
  • The role of membrane-associated adaptors in T cell receptor signalling. 
  • The role of orphan nuclear receptor in thymocyte differentiation and lymphoid organ development. 
  • The role of the L3T4 molecule in mitogen and antigen-activated signal transduction. 
  • The role of the thymic microenvironment in promotion of early stages of human T cell maturation. 
  • The role of the thymus in immune reconstitution in aging, bone marrow transplantation, and HIV-1 infection. 
  • The role of type 1 angiotensin receptors on T lymphocytes in cardiovascular and renal diseases. 
  • The same epitope on CD22 of B lymphocytes mediates the adhesion of erythrocytes, T and B lymphocytes, neutrophils, and monocytes. 
  • The six-nucleotide deletion/insertion variant in the CASP8 promoter region is inversely associated with risk of squamous cell carcinoma of the head and neck. 
  • The stimulatory potency of T cell antigens is influenced by the formation of the immunological synapse. 
  • The structure and function of gamma c-dependent cytokines and receptors: regulation of T lymphocyte development and homeostasis. 
  • The thymus as an inductive site for T lymphopoiesis. 
  • The tumor dormant state. Quantitation of L5178Y cells and host immune responses during the establishment and course of dormancy in syngeneic DBA/2 mice. 
  • This paper is the winner of an SFB Award in the Hospital Intern, Residency category: Peptide biomaterials raising adaptive immune responses in wound healing contexts. 
  • Three is better than one: pre-ligand receptor assembly in the regulation of TNF receptor signaling. 
  • Thymic epithelial defects and predisposition to autoimmune disease in BB rats. 
  • Thymic expression of the transcription factor Nur77 rescues the T cell but not the B cell abnormality of gld/gld mice. 
  • Thymic function after hematopoietic stem-cell transplantation for the treatment of severe combined immunodeficiency. 
  • Thymic function, aging, and AIDS. 
  • Thymic microenvironment reconstitution after postnatal human thymus transplantation. 
  • Thymic output, T-cell diversity, and T-cell function in long-term human SCID chimeras. 
  • Thymic requirement for cyclical idiotypic and reciprocal anti-idiotypic immune responses to a T-independent antigen. 
  • Thymocyte LFA-1 and thymic epithelial cell ICAM-1 molecules mediate binding of activated human thymocytes to thymic epithelial cells. 
  • Thymocyte binding to human thymic epithelial cells is inhibited by monoclonal antibodies to CD-2 and LFA-3 antigens. 
  • Thymocytes and cultured thymic epithelial cells express transcripts encoding alpha-3, alpha-5, and beta-4 subunits of neuronal nicotinic acetylcholine receptors. Preferential transcription of the alpha-3 and beta-4 genes by immature CD4+8+ thymocytes and evidence for response to nicotine in thymocytes. 
  • Thymoma: lymphoid and epithelial components mirror the phenotype of normal thymus. 
  • Thymopoiesis in HIV-infected adults after highly active antiretroviral therapy. 
  • Thymus transplantation for complete DiGeorge syndrome: European experience. 
  • Thymus transplantation in complete DiGeorge syndrome: immunologic and safety evaluations in 12 patients. 
  • Thymus transplantation. 
  • Timing of plasmid cytokine (IL-2/Ig) administration affects HIV-1 vaccine immunogenicity in HIV-seronegative subjects. 
  • Tissue plasminogen activator (tPA) signal sequence enhances immunogenicity of MVA-based vaccine against tuberculosis. 
  • Tolerance mechanisms and recent progress. 
  • Toll-like receptors in tumor immunotherapy. 
  • Toward an understanding of the correlates of protective immunity to HIV infection. 
  • Toward effective immunotherapy for the treatment of malignant brain tumors. 
  • Transcription factor LKLF is sufficient to program T cell quiescence via a c-Myc-dependent pathway. 
  • Transcription factor NF-kappaB regulates inducible CD83 gene expression in activated T lymphocytes. 
  • Transcriptional regulation of T lymphocyte development and function. 
  • Transcriptomic analysis of peripheral blood mononuclear cells in rapid progressors in early HIV infection identifies a signature closely correlated with disease progression 
  • Transfer of allogeneic CD62L- memory T cells without graft-versus-host disease. 
  • Transgenic mice expressing dominant-negative bright exhibit defects in B1 B cells. 
  • Transient combination therapy targeting the immune synapse abrogates T cell responses and prolongs allograft survival in mice. 
  • Transient subversion of CD40 ligand function diminishes immune responses to adenovirus vectors in mouse liver and lung tissues. 
  • Transmission of HIV by antigen presenting cells during T-cell activation: prevention by 3'-azido-3'-deoxythymidine. 
  • Transplantation of hematopoietic stem cells in human severe combined immunodeficiency: longterm outcomes. 
  • Transplantation of thymus tissue in complete DiGeorge syndrome. 
  • Transplantation outcomes for severe combined immunodeficiency, 2000-2009. 
  • Treatment of autoimmune disease with extracorporeal photochemotherapy: pemphigus vulgaris--preliminary report. 
  • Treatment of chronic granulomatous disease with nonmyeloablative conditioning and a T-cell-depleted hematopoietic allograft. 
  • Treatment of cutaneous T cell lymphoma with 2'-deoxycoformycin (pentostatin). 
  • Treatment of rheumatoid arthritis with a DR4/1 peptide. 
  • Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates. 
  • Treatment with immunotoxin. 
  • Tumor MHC class I expression improves the prognostic value of T-cell density in resected colorectal liver metastases. 
  • Tumor microenvironment: what have we learned studying the immune response in this puzzling battlefield? 
  • Tumor suppressor TSC1 is critical for T-cell anergy. 
  • Tumors as elusive targets of T-cell-based active immunotherapy. 
  • Turning T-cell receptor beta recombination on and off: more questions than answers. 
  • Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain. 
  • Unarmed, tumor-specific monoclonal antibody effectively treats brain tumors. 
  • Understanding specificity and sensitivity of T-cell recognition. 
  • Unexpected role of clathrin adaptor AP-1 in MHC-dependent positive selection of T cells. 
  • Unexpected role of interferon-γ in regulating neuronal connectivity and social behaviour. 
  • Unidirectional, heterologous desensitization of the pertussis toxin receptor by the CD3/TCR complex. 
  • Unique aspects of rejection and tolerance in liver transplantation. 
  • Unusual clinical and immunologic manifestations of transplacentally acquired maternal T cells in severe combined immunodeficiency. 
  • Upregulation of class I major histocompatibility complex antigens by interferon gamma is necessary for T-cell-mediated elimination of recombinant adenovirus-infected hepatocytes in vivo. 
  • Use of a human plaque-forming cell assay to study peripheral blood bursa-equivalent cell activation and excessive suppressor cell activity in humoral immunodeficiency. 
  • Use of allograft biopsies to assess thymopoiesis after thymus transplantation. 
  • Using an adaptive gene network model for self-organizing multicellular behavior. 
  • V(D)J recombinase-mediated processing of coding junctions at cryptic recombination signal sequences in peripheral T cells during human development. 
  • VEGF inhibits T-cell development and may contribute to tumor-induced immune suppression. 
  • Vaccination With Heterologous HIV-1 Envelope Sequences and Heterologous Adenovirus Vectors Increases T-Cell Responses to Conserved Regions: HVTN 083. 
  • Vaccination with T cell-defined antigens. 
  • Variation in DNA and RNA synthetic responses during activation of lymphocytes from inbred strains of mice. 
  • Vascular endothelial growth factor impairs the functional ability of dendritic cells through Id pathways. 
  • Vav and Rac activation in B cell antigen receptor endocytosis involves Vav recruitment to the adapter protein LAB. 
  • Very low affinity B cells form germinal centers, become memory B cells, and participate in secondary immune responses when higher affinity competition is reduced. 
  • Vincristine therapy for severe platelet alloimmunization. 
  • Virus-immune cytotoxic T cells recognize structural differences between serologically indistinguishable HLA-A2 molecules. 
  • What keeps a resting T cell alive? 
  • What's new--what's hot in basic science: American Transplant Congress 2004. 
  • Why newborn screening for severe combined immunodeficiency is essential: a case report. 
  • Workshop on immunizations in older adults: identifying future research agendas. 
  • X-linked lymphoproliferative disease (XLP): a model of impaired anti-viral, anti-tumor and humoral immune responses. 
  • X-linked severe combined immunodeficiency. Diagnosis in males with sporadic severe combined immunodeficiency and clarification of clinical findings. 
  • ZAP-70 tyrosine kinase is required for the up-regulation of Fas ligand in activation-induced T cell apoptosis. 
  • [Characteristics of cells producing immune interferon]. 
  • [Expression of presenilin 1 on the cell surface in motile polarized cells]. 
  • [IL-21 induces regulatory B cell differentiation and immunosuppressive effect through cognate interaction with T cells]. 
  • bcl-2 transgenic Lpr mice show profound enhancement of lymphadenopathy. 
  • c-FLIP protects T lymphocytes from apoptosis in the intrinsic pathway. 
  • c-FLIP protects mature T lymphocytes from TCR-mediated killing. 
  • c-Myb and core-binding factor/PEBP2 display functional synergy but bind independently to adjacent sites in the T-cell receptor delta enhancer. 
  • mTORC1 in Thymic Epithelial Cells Is Critical for Thymopoiesis, T-Cell Generation, and Temporal Control of γδT17 Development and TCRγ/δ Recombination. 
  • mTORC2 in Thymic Epithelial Cells Controls Thymopoiesis and T Cell Development. 
  • miR-181a is an intrinsic modulator of T cell sensitivity and selection. 
  • p53 functional impairment and high p21waf1/cip1 expression in human T-cell lymphotropic/leukemia virus type I-transformed T cells. 
  • rHuEPO and improved treatment outcomes: potential modes of action. 
  • α4β7 Integrin is essential for contact hypersensitivity by regulating migration of T cells to skin. 
• 

  Keywords of People

  • Barfield, Raymond Carlton, Professor of Pediatrics, Duke Science & Society
  • Barker, Piers Christopher Andrew, Professor of Pediatrics, Pediatrics, Cardiology
  • Buckley, Rebecca Hatcher, James Buren Sidbury Professor of Pediatrics, in the School of Medicine, Immunology
  • Chen, Jun, Associate Professor of Medicine, Duke Cancer Institute
  • Choi, Steven Sok, Associate Professor of Medicine, Medicine, Gastroenterology
  • Cianciolo, George James, Associate Professor in Pathology, Pathology
  • Ciofani, Maria, Assistant Professor of Immunology, Immunology
  • Cunningham, Coleen Kathryn, Professor of Pediatrics, Pathology
  • Ferrari, Guido, Associate Professor of Surgery, Molecular Genetics and Microbiology
  • Gunn, Michael Dee, Professor of Medicine, Immunology
  • Kelsoe, Garnett H., James B. Duke Professor of Immunology, Immunology
  • Krangel, Michael S., Mary Bernheim Professor of Immunology, Immunology
  • Lee, Walter T, Associate Professor of Surgery, Radiation Oncology
  • McDonnell, Donald Patrick, Chair, Department of Pharmacology & Cancer Biology, Duke Innovation & Entrepreneurship
  • McLendon, Roger Edwin, Professor of Pathology, Pathology
  • Mosca, Paul Joseph, Associate Professor of Surgery, Surgical Oncology
  • Pitt, Geoffrey Stuart, Adjunct Professor in the Department of Medicine, Medicine, Cardiology
  • Sampson, John Howard, Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine, Immunology
  • Schanberg, Laura Eve, Professor of Pediatrics, Pediatrics, Rheumatology
  • Shinohara, Mari L., Associate Professor of Immunology, Immunology
  • Soderling, Scott Haydn, Professor in Cell Biology, Cell Biology
  • Sunday, Mary Elizabeth Anne, Professor of Pathology, Cell Biology
  • Taylor, Gregory Alan, Associate Professor in Medicine, Immunology
  • Weinhold, Kent James, Joseph W. and Dorothy W. Beard Professor of Experimental Surgery, in the School of Medicine, Immunology
  • Yang, Yiping, Professor of Medicine, Immunology
  • Zhong, Xiaoping, Professor of Pediatrics, Immunology