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Subject Areas on Research
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A mechanism-based complementary screening approach for the amelioration and reversal of neurobehavioral teratogenicity.
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An evaluative process for assessing human reproductive and developmental toxicity of agents.
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Antiepileptic Drug Teratogenicity and De Novo Genetic Variation Load.
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Autophagy-dependent metabolic reprogramming sensitizes TSC2-deficient cells to the antimetabolite 6-aminonicotinamide.
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Bipolar Depression: Pregnancy, Postpartum, and Lactation.
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Cell signaling as a target and underlying mechanism for neurobehavioral teratogenesis.
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Chlorpyrifos elicits mitotic abnormalities and apoptosis in neuroepithelium of cultured rat embryos.
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Cloning genes that encode drug-metabolizing enzymes: developmental pharmacology and teratology.
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Compound- and mixture-specific differences in resistance to polycyclic aromatic hydrocarbons and PCB-126 among Fundulus heteroclitus subpopulations throughout the Elizabeth River estuary (Virginia, USA).
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Convergent effects on cell signaling mechanisms mediate the actions of different neurobehavioral teratogens: alterations in cholinergic regulation of protein kinase C in chick and avian models.
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Criteria for identifying and listing substances known to cause reproductive toxicity under California's Proposition 65.
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Critical review: nicotine for the fetus, the infant and the adolescent?
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Developmental exposure to terbutaline alters cell signaling in mature rat brain regions and augments the effects of subsequent neonatal exposure to the organophosphorus insecticide chlorpyrifos.
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Developmental exposure to terbutaline and chlorpyrifos: pharmacotherapy of preterm labor and an environmental neurotoxicant converge on serotonergic systems in neonatal rat brain regions.
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Dynamic zebrafish interactome reveals transcriptional mechanisms of dioxin toxicity.
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Early biochemical detection of adverse effects of a neurobehavioral teratogen: influence of prenatal methylmercury exposure on ornithine decarboxylase in brain and other tissues of fetal and neonatal rat.
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Effects of fetal dexamethasone exposure on postnatal control of cardiac adenylate cyclase: beta-adrenergic receptor coupling to Gs regulatory protein.
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Embryo toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin to the wood duck (Aix sponsa).
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Evaluating chemical and other agent exposures for reproductive and developmental toxicity.
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Exposure of developing chicks to perfluorooctanoic acid induces defects in prehatch and early posthatch development.
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Exposure to 1,2-Propanediol Impacts Early Development of Zebrafish (Danio rerio) and Induces Hyperactivity.
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Fetal alcohol exposure impairs Hedgehog cholesterol modification and signaling.
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Fetal cocaine exposure causes persistent noradrenergic hyperactivity in rat brain regions: effects on neurotransmitter turnover and receptors.
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Heroin neuroteratogenicity: targeting adenylyl cyclase as an underlying biochemical mechanism.
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Identification of rat yolk sac target protein of teratogenic antibodies, gp280, as intrinsic factor-cobalamin receptor.
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Improving the Safety of Teratogen Prescribing Practices in a Pediatric Rheumatology Clinic.
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In search of a mechanism for receptor-mediated neurobehavioral teratogenesis by nicotine: catecholamine release by nicotine in immature rat brain regions.
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Joint models for toxicology studies with dose-dependent number of implantations.
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Later life swimming performance and persistent heart damage following subteratogenic PAH mixture exposure in the Atlantic killifish (Fundulus heteroclitus).
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NIEHS/EPA Workshops. Growth and differentiation factors.
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NIEHS/EPA Workshops. Pattern formation.
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Neurobehavioral teratogenicity of perfluorinated alkyls in an avian model.
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Neurobehavioral teratogenicity of sarin in an avian model.
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Nicotine evokes cell death in embryonic rat brain during neurulation.
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Normal development of the human female reproductive tract and alterations resulting from experimental exposure to diethylstilbestrol.
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Prenatal cocaine and/or nicotine exposure in rats: preliminary findings on long-term cognitive outcome and genital development at birth.
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Prenatal exposure to toluene results in abnormal neurogenesis and migration in rat somatosensory cortex.
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Prevention of fumonisin B1-induced neural tube defects by folic acid.
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Response to the letter of Hanley et al. ([1999] Teratology 59:323-324), concerning the article by Roy et al. ([1998] Teratology 58:62-68)
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Retinoic acid-mediated gene expression in transgenic reporter zebrafish.
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Reversal of chlorpyrifos neurobehavioral teratogenicity in mice by allographic transplantation of adult subventricular zone-derived neural stem cells.
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Teratogenic, bioenergetic, and behavioral effects of exposure to total particulate matter on early development of zebrafish (Danio rerio) are not mimicked by nicotine.
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The effect of fumonisin B1 on developing chick embryos: correlation between de novo sphingolipid biosynthesis and gross morphological changes.
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The intrinsic factor-vitamin B12 receptor and target of teratogenic antibodies is a megalin-binding peripheral membrane protein with homology to developmental proteins.
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The transcriptional response to oxidative stress during vertebrate development: effects of tert-butylhydroquinone and 2,3,7,8-tetrachlorodibenzo-p-dioxin.
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Use of human cumulus granulosa cells for in vitro screening of reproductive toxicants.