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Subject Areas on Research
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"Blueprinting" thrombogenicity and antithrombotic drug response at the bedside in patients presenting emergently with symptoms of acute stroke.
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"Systematic review of viscoelastic testing (TEG/ROTEM) in obstetrics and recommendation from the women's SSC of the ISTH": Response to comment from Kitchen et al.
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A comparative evaluation of rotation thromboelastometry and standard coagulation tests in hemodilution-induced coagulation changes after cardiac surgery.
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A conundrum: general or neuraxial anesthesia and the use of ROTEM.
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A novel method to assess platelet inhibition by eptifibatide with thrombelastograph.
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A prospective, randomized comparison of thromboelastographic coagulation profile in patients receiving lactated Ringer's solution, 6% hetastarch in a balanced-saline vehicle, or 6% hetastarch in saline during major surgery.
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A systematic review of thromboelastography utilization in vascular and endovascular surgery.
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Adenosine diphosphate-induced platelet-fibrin clot strength: a new thrombelastographic indicator of long-term poststenting ischemic events.
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Anticoagulation and reversal paradigms: is too much of a good thing bad?
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Antiplatelet Effect Durability of a Novel, 24-Hour, Extended-Release Prescription Formulation of Acetylsalicylic Acid in Patients With Type 2 Diabetes Mellitus.
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Argatroban "reversal" is caused by nonphysiologic stimulation of coagulation, not activated factor VII.
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Association of weight gain with coronary artery disease, inflammation and thrombogenicity.
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Bedside thromboelastography to rapidly assess the pharmacodynamic response of anticoagulants and aspirin in COVID-19: evidence of inadequate therapy in a predominantly minority population.
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Bivalirudin and clopidogrel with and without eptifibatide for elective stenting: effects on platelet function, thrombelastographic indexes, and their relation to periprocedural infarction results of the CLEAR PLATELETS-2 (Clopidogrel with Eptifibatide to Arrest the Reactivity of Platelets) study.
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Bleeding and management of coagulopathy.
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Central aortic pulse pressure, thrombogenicity and cardiovascular risk.
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Clopidogrel (Plavix) and cardiac surgical patients: implications for platelet function monitoring and postoperative bleeding.
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Coagulopathy Characterized by Rotational Thromboelastometry in a Porcine Pediatric ECMO Model.
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Delayed thrombin-induced platelet-fibrin clot generation by clopidogrel: a new dose-related effect demonstrated by thrombelastography in patients undergoing coronary artery stenting.
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Determination of non-Vitamin K oral anticoagulant (NOAC) effects using a new-generation thrombelastography TEG 6s system.
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Drop-of-blood acoustic tweezing technique for integrative turbidimetric and elastometric measurement of blood coagulation.
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Effect of two doses of tranexamic acid on fibrinolysis evaluated by thromboelastography during cardiac surgery: a randomised, controlled study.
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Effects of a plasma-derived C1 esterase inhibitor on hemostatic activation, clot formation, and thrombin generation.
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Effects of recombinant activated factor VII on thrombin-mediated feedback activation of coagulation.
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Evaluation of a novel kallikrein inhibitor on hemostatic activation in vitro.
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Evaluation of dose-related effects of aspirin on platelet function: results from the Aspirin-Induced Platelet Effect (ASPECT) study.
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Evaluation of dynamic parameters of thrombus formation measured on whole blood using rotational thromboelastometry in children undergoing cardiac surgery: a descriptive study.
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Fibrinogen and bleeding: old molecule--new ideas.
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Finding the optimal concentration range for fibrinogen replacement after severe haemodilution: an in vitro model.
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First report of the point-of-care TEG: A technical validation study of the TEG-6S system.
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Functional maturity of the coagulation system in children: an evaluation using thrombelastography.
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Gender differences in thrombogenicity among patients with angina and non-obstructive coronary artery disease.
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Haemodilution-induced profibrinolytic state is mitigated by fresh-frozen plasma: implications for early haemostatic intervention in massive haemorrhage.
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Hematologic and economic impact of aprotinin in reoperative pediatric cardiac operations.
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Heparin neutralization by recombinant platelet factor 4 and protamine.
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Hypercoagulability, platelet function, inflammation and coronary artery disease acuity: results of the Thrombotic RIsk Progression (TRIP) study.
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In vitro comparative study of hemostatic components in warfarin-treated and fibrinogen-deficient plasma.
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In vitro effects of recombinant activated factor VII on thrombin generation and coagulation following inhibition of platelet procoagulant activity by prasugrel.
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In-vitro evaluation of anti-factor IXa aptamer on thrombin generation, clotting time, and viscoelastometry.
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Increased risk in patients with high platelet aggregation receiving chronic clopidogrel therapy undergoing percutaneous coronary intervention: is the current antiplatelet therapy adequate?
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Influence of Amlodipine on Haemostatic Measurements during Clopidogrel Treatment in Patients with Coronary Artery Disease.
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Influence of race and sex on thrombogenicity in a large cohort of coronary artery disease patients.
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Key Pathogenic Factors in Coronavirus Disease 2019-Associated Coagulopathy and Acute Lung Injury Highlighted in a Patient With Copresentation of Acute Myelocytic Leukemia: A Case Report.
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Low plasma fibrinogen levels with the Clauss method during anticoagulation with bivalirudin.
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Multicenter Evaluation of the Quantra QPlus System in Adult Patients Undergoing Major Surgical Procedures.
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Nucleic acid scavengers inhibit thrombosis without increasing bleeding.
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Optimal use of intravenous tranexamic acid for hemorrhage prevention in pregnant women.
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Overestimation of platelet aspirin resistance detection by thrombelastograph platelet mapping and validation by conventional aggregometry using arachidonic acid stimulation.
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Personalizing Antithrombotic Therapy in COVID-19: Role of Thromboelastography and Thromboelastometry.
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Pharmacodynamic effects of a new fixed-dose clopidogrel-aspirin combination compared with separate administration of clopidogrel and aspirin in patients treated with coronary stents: The ACCEL-COMBO trial.
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Platelet Function Changes in a Time-Dependent Manner Following Traumatic Brain Injury in a Murine Model.
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Platelet function measurement-based strategy to reduce bleeding and waiting time in clopidogrel-treated patients undergoing coronary artery bypass graft surgery: the timing based on platelet function strategy to reduce clopidogrel-associated bleeding related to CABG (TARGET-CABG) study.
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Point of care devices for assessing bleeding and coagulation in the trauma patient.
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Postpartum hemorrhage management in 2012: predicting the future.
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Predicting and treating coagulopathies after cardiopulmonary bypass in children.
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Race and sex differences in thrombogenicity: risk of ischemic events following coronary stenting.
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Rapid evaluation of coagulopathies after cardiopulmonary bypass in children using modified thromboelastography.
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Relation of fish oil supplementation to markers of atherothrombotic risk in patients with cardiovascular disease not receiving lipid-lowering therapy.
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Reversal of dabigatran effects in models of thrombin generation and hemostasis by factor VIIa and prothrombin complex concentrate.
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Rotational thromboelastometry-guided blood product management in major spine surgery.
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Rotational thromboelastometry-guided transfusion during lumbar pedicle subtraction osteotomy for adult spinal deformity: preliminary findings from a matched cohort study.
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Statin therapy and thromboxane generation in patients with coronary artery disease treated with high-dose aspirin.
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Systematic review of viscoelastic testing (TEG/ROTEM) in obstetrics and recommendations from the women's SSC of the ISTH.
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The Impact of platelet-fibrin clot strength on occurrence and clinical outcomes of peripheral artery disease in patients with significant coronary artery disease.
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The anticoagulant effect of protamine sulfate is attenuated in the presence of platelets or elevated factor VIII concentrations.
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The effect of elinogrel on high platelet reactivity during dual antiplatelet therapy and the relation to CYP2C19*2 genotype: first experience in patients.
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The effect of ionised magnesium on coagulation using thromboelastography.
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The effect of pathogen inactivation on cryoprecipitate: a functional and quantitative evaluation.
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The effects of milrinone on platelets in patients undergoing cardiac surgery.
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The effects of platelet count on clot retraction and tissue plasminogen activator-induced fibrinolysis on thrombelastography.
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The kaolin-activated Thrombelastograph predicts bleeding after cardiac surgery.
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The link between heightened thrombogenicity and inflammation: pre-procedure characterization of the patient at high risk for recurrent events after stenting.
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The procoagulant properties of purified fibrinogen concentrate are enhanced by carbon monoxide releasing molecule-2.
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The role of viscoelastic testing in assessing peri-interventional platelet function and coagulation.
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Thrombin generation assay and viscoelastic coagulation monitors demonstrate differences in the mode of thrombin inhibition between unfractionated heparin and bivalirudin.
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Thrombin-Induced Platelet-Fibrin Clot Strength Identified by Thrombelastography: A Novel Prothrombotic Marker of Coronary Artery Stent Restenosis.
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Thrombin-activated thrombelastography for evaluation of thrombin interaction with thrombin inhibitors.
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Thrombin-induced platelet-fibrin clot strength: relation to high on-clopidogrel platelet reactivity, genotype, and post-percutaneous coronary intervention outcomes.
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Thromboelastography and rotational thromboelastometry in bleeding patients with coagulopathy: Practice management guideline from the Eastern Association for the Surgery of Trauma.
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Thromboelastography as a perioperative measure of anticoagulation resulting from low molecular weight heparin: a comparison with anti-Xa concentrations.
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Thromboelastography detects inadequate response to abciximab therapy during stent-assisted cerebral aneurysm coil embolization complicated by stroke.
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Thrombogenicity markers for early diagnosis and prognosis in COVID-19: a change from the current paradigm?
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Tissue factor-activated thromboelastograms in children undergoing cardiac surgery: baseline values and comparisons.
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Update on massive transfusion.
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Use of Earlier-Reported Rotational Thromboelastometry Parameters to Evaluate Clotting Status, Fibrinogen, and Platelet Activities in Postpartum Hemorrhage Compared to Surgery and Intensive Care Patients.
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Usefulness of thrombelastography platelet mapping assay to measure the antiplatelet effect of P2Y(12) receptor inhibitors and high on-treatment platelet reactivity.
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Using antifibrinolytics in the peripartum period - concern for a hypercoagulable effect?
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Utility of viscoelastic coagulation testing in liver surgery: a systematic review.
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Utilization of Thromboelastography with Platelet Mapping to Predict Infection and Poor Wound Healing in Postoperative Vascular Patients.
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Viscoelastic Coagulation Testing: Use and Current Limitations in Perioperative Decision-making.
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Viscoelastic properties of clot formation and their clinical impact in East Asian versus Caucasian patients with stable coronary artery disease: a COMPARE-RACE analysis.
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Viscoelastic testing to assess the effects of rapid fibrinogen concentrate administration after cardiopulmonary bypass: insights from the REPLACE study.
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Warfarin reversal with prothrombin complex concentrate confers better antifibrinolytic activity compared with recombinant activated factor VII.