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Subject Areas on Research
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A Step Toward Balance: Thrombin Generation Improvement via Procoagulant Factor and Antithrombin Supplementation.
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A c-Fos- and E1A-interacting component of the tissue factor basal promoter complex mediates synergistic activation of transcription by transforming growth factor-beta1.
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A cell-based model of thrombin generation.
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A commentary on "A rapid, sensitive and specific assay to measure TF activity based on chromogenic determination of thrombin generation".
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A model for the tissue factor pathway to thrombin. I. An empirical study.
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A possible mechanism of action of activated factor VII independent of tissue factor.
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A unique protein kinase C-dependent pathway for tissue factor downregulation in pericytes.
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A20 protects from CD40-CD40 ligand-mediated endothelial cell activation and apoptosis.
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Aberrant NF-kappaB activity is critical in focal necrosis formation of human glioblastoma by regulation of the expression of tissue factor.
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Activated protein C cleaves factor Va more efficiently on endothelium than on platelet surfaces.
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Active site-inactivated factors VIIa, Xa, and IXa inhibit individual steps in a cell-based model of tissue factor-initiated coagulation.
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Aminonaphthalenesulfonamides, a new class of modifiable fluorescent detecting groups and their use in substrates for serine protease enzymes.
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An activated factor VII variant with enhanced tissue factor-independent activity speeds wound healing in a mouse hemophilia B model.
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Antibodies from patients with heparin-induced thrombocytopenia stimulate monocytic cells to express tissue factor and secrete interleukin-8.
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Autoantibodies against the cell surface-associated chaperone GRP78 stimulate tumor growth via tissue factor.
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Bench to bedside: targeting coagulation and fibrinolysis in acute lung injury.
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Binding of anti-GRP78 autoantibodies to cell surface GRP78 increases tissue factor procoagulant activity via the release of calcium from endoplasmic reticulum stores.
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Blockade of tissue factor-factor X binding attenuates sepsis-induced respiratory and renal failure.
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Blockade of tissue factor: treatment for organ injury in established sepsis.
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Cellular interactions in hemostasis.
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Circulating tissue factor accumulates in thrombi, but not in hemostatic plugs.
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Coagulation blockade prevents sepsis-induced respiratory and renal failure in baboons.
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Complement-induced vesiculation and exposure of membrane prothrombinase sites in platelets of paroxysmal nocturnal hemoglobinuria.
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Complex-dependent inhibition of factor VIIa by antithrombin III and heparin.
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Cooperative activation of human factor IX by the human extrinsic pathway of blood coagulation.
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Cooperative interaction of divalent metal ions, substrate, and tissue factor with factor VIIa.
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D-Dimer in African Americans: Whole Genome Sequence Analysis and Relationship to Cardiovascular Disease Risk in the Jackson Heart Study.
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Deencryption of cellular tissue factor is independent of its cytoplasmic domain.
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Development of DX-9065a, a novel direct factor Xa antagonist, in cardiovascular disease.
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Differential expression of tissue factor protein in directional atherectomy specimens from patients with stable and unstable coronary syndromes.
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Disseminated intravascular coagulation (DIC): an approach.
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Dysregulation of hemostasis by cancer.
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Expression of tissue factor in tumor stroma correlates with progression to invasive human breast cancer: paracrine regulation by carcinoma cell-derived members of the transforming growth factor beta family.
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Extravascular fibrin formation and dissolution in synovial tissue of patients with osteoarthritis and rheumatoid arthritis.
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Extrinsic coagulation blockade attenuates lung injury and proinflammatory cytokine release after intratracheal lipopolysaccharide.
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Extrinsic pathway proteolytic activity.
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Factor Xa induces tissue factor expression in endothelial cells by P44/42 MAPK and NF-κB-dependent pathways.
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Factors IXa and Xa play distinct roles in tissue factor-dependent initiation of coagulation.
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Fine mapping of inhibitory anti-factor V antibodies using factor V C2 domain mutants. Identification of two antigenic epitopes involved in phospholipid binding.
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Glioblastoma cell populations with distinct oncogenic programs release podoplanin as procoagulant extracellular vesicles.
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HIV envelope gp120 activates human arterial smooth muscle cells.
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Human monocytes support factor X activation by factor VIIa, independent of tissue factor: implications for the therapeutic mechanism of high-dose factor VIIa in hemophilia.
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Hypercoagulable states in cardiovascular disease.
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Infant cardiopulmonary bypass: a procoagulant state.
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Inflammation does not predispose to bleeding in hemophilia.
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Ischemia/reperfusion injury in microvascular surgery.
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Manipulation of prothrombin concentration improves response to high-dose factor VIIa in a cell-based model of haemophilia.
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Microparticles in the blood of patients with systemic lupus erythematosus (SLE): phenotypic characterization and clinical associations.
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Monitoring warfarin therapy in patients with lupus anticoagulants.
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Newer concepts of blood coagulation.
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P-selectin induces the expression of tissue factor on monocytes.
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PF4/heparin-antibody complex induces monocyte tissue factor expression and release of tissue factor positive microparticles by activation of FcγRI.
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Partial glycosylation at asparagine-2181 of the second C-type domain of human factor V modulates assembly of the prothrombinase complex.
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Perivascular tissue factor is down-regulated following cutaneous wounding: implications for bleeding in hemophilia.
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Platelet activity of high-dose factor VIIa is independent of tissue factor.
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Platelet binding and activity of a factor VIIa variant with enhanced tissue factor independent activity.
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Platelet procoagulant complex assembly in a tissue factor-initiated system.
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Platelet-dependent action of high-dose factor VIIa.
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Porcine endothelial cells cocultured with smooth muscle cells became procoagulant in vitro.
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Rapid evaluation of coagulopathies after cardiopulmonary bypass in children using modified thromboelastography.
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Rethinking the coagulation cascade.
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Sodium binding site of factor Xa: role of sodium in the prothrombinase complex.
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Some things I thought I knew about tissue factor that turn out to be wrong.
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Sphingosine inhibits monocyte tissue factor-initiated coagulation by altering factor VII binding.
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Suppression of Fibrinolysis and Hypercoagulability, Severity of Hypoxemia, and Mortality in COVID-19 Patients: A Retrospective Cohort Study.
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Surface-dependent hemostasis.
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Synovial mononuclear phagocytes in rheumatoid arthritis and osteoarthritis: quantitative and functional aspects.
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The Tissue Factor Pathway and Wound Healing.
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The action of high-dose factor VIIa (FVIIa) in a cell-based model of hemostasis.
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The coagulation cascade in cirrhosis.
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The effect of active site-inhibited factor VIIa on tissue factor-initiated coagulation using platelets before and after aspirin administration.
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The effect of pathogen inactivation on cryoprecipitate: a functional and quantitative evaluation.
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The effect of temperature and pH on the activity of factor VIIa: implications for the efficacy of high-dose factor VIIa in hypothermic and acidotic patients.
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The effects of activated factor VII in a cell-based model for tissue factor-initiated coagulation.
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The evaluation of complex-dependent alterations in human factor VIIa.
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The immune consequences of trauma.
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The multiple roles of tissue factor in wound healing.
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The next best thing in factor VIIa.
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The subunit structure of normal and hemophilic factor VIII.
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Thrombogenesis in atrial fibrillation contributing mechanisms and natural history.
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Tissue factor and fibrin in tumor angiogenesis.
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Tissue factor around dermal vessels has bound factor VII in the absence of injury.
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Tissue factor de-encryption: ionophore treatment induces changes in tissue factor activity by phosphatidylserine-dependent and -independent mechanisms.
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Tissue factor in brain is not saturated with factor VIIa: implications for factor VIIa dosing in intracerebral hemorrhage.
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Tissue factor in experimental acute lung injury.
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Tissue factor is the receptor for plasminogen type 1 on 1-LN human prostate cancer cells.
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Tissue factor, thrombin, and cancer.
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Tissue factor-activated thromboelastograms in children undergoing cardiac surgery: baseline values and comparisons.
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Translating nucleic acid aptamers to antithrombotic drugs in cardiovascular medicine.
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Transmission of a procoagulant signal from tissue factor-bearing cell to platelets.
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Tumor necrosis factor induces tissue factor-like activity in human leukemia cell line U937 and peripheral blood monocytes.
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Variability in platelet procoagulant activity in healthy volunteers.
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Vascular endothelial tissue factor pathway inhibitor kinetics in culture following exposure to DX-9065a--a selective and direct factor Xa inhibitor.
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Wound healing in hemophilia B mice and low tissue factor mice.
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Keywords of People