Thymidine Kinase
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Subject Areas on Research
- A herpes simplex virus 1 integration site in the mouse genome defined by somatic cell genetic analysis.
- A novel mouse model of depletion of stellate cells clarifies their role in ischemia/reperfusion- and endotoxin-induced acute liver injury.
- A p-[18F]fluoroethoxyphenyl bicyclic nucleoside analogue as a potential positron emission tomography imaging agent for varicella-zoster virus thymidine kinase gene expression.
- A simple method to cure established tumors by inflammatory killing of normal cells.
- Aedes albopictus cells resistant to adenosine because of a defect in nucleoside transport.
- Airway injury in lung disease pathophysiology: selective depletion of airway stem and progenitor cell pools potentiates lung inflammation and alveolar dysfunction.
- Angiotensin II can regulate gene expression by the AP-1 binding sequence via a protein kinase C-dependent pathway.
- Antineoplastic activity of a series of boron analogues of alpha-amino acids.
- Conditionally replicating lentiviral-hybrid episomal vectors for suicide gene therapy.
- DNA fragments from F9 PyEC mutants increase expression of heterologous genes in transfected F9 cells.
- Directed enzyme pro-drug gene therapy for pancreatic cancer in vivo.
- Discrete amino acid sequences of the alpha 1-adrenergic receptor determine the selectivity of coupling to phosphatidylinositol hydrolysis.
- Elevated frequency of microsatellite mutations in TK6 human lymphoblast clones selected for mutations at the thymidine kinase locus.
- Eradication of solid human breast tumors in nude mice with an intravenously injected light-emitting oncolytic vaccinia virus.
- Estrogen and thyroid hormone interaction on regulation of gene expression.
- Evidence for coincident mutations in human lymphoblast clones selected for functional loss of a thymidine kinase gene.
- Functions of fission yeast orp2 in DNA replication and checkpoint control.
- Generation of reovirus core-like particles in cells infected with hybrid vaccinia viruses that express genome segments L1, L2, L3, and S2.
- Imaging of musculoskeletal bacterial infections by [124I]FIAU-PET/CT.
- Impaired fear response in mice lacking GIT1.
- Induction of cell stress through gene transfer of an engineered heat shock transcription factor enhances tumor immunogenicity.
- Inhibition of glycosylation of bovine herpesvirus 1 glycoproteins by the thymidine analog (E)-5-(2 Bromovinyl)-2'-deoxyuridine.
- Molecular mechanisms of spontaneous and induced loss of heterozygosity in human cells in vitro.
- Oncolytic adenovirus delivering herpes simplex virus thymidine kinase suicide gene reduces the growth of human retinoblastoma in an in vivo mouse model.
- Preliminary validation of varicella zoster virus thymidine kinase as a novel reporter gene for PET.
- Prolactin induction of insulin gene transcription: roles of glucose and signal transducer and activator of transcription 5.
- Reduced expression of brain-enriched microRNAs in glioblastomas permits targeted regulation of a cell death gene.
- Retroviral vector gene expression in F9 embryonal carcinoma cells.
- Schwann cell influence on motor neuron regeneration accuracy.
- Synergy of adoptive T-cell therapy and intratumoral suicide gene therapy is mediated by host NK cells.
- Synthesis and biological evaluation of an 123I-labeled bicyclic nucleoside analogue (BCNA) as potential SPECT tracer for VZV-tk reporter gene imaging.
- Synthesis and preliminary evaluation of 18F- or 11C-labeled bicyclic nucleoside analogues as potential probes for imaging varicella-zoster virus thymidine kinase gene expression using positron emission tomography.
- Targeted Treatment of Experimental Spinal Cord Glioma With Dual Gene-Engineered Human Neural Stem Cells.
- The need for enhancers in gene expression first appears during mouse development with formation of the zygotic nucleus.
- Transgenic indicator mice for studying activated retinoic acid receptors during development.
- VSV-G pseudotyped, MuLV-based, semi-replication-competent retrovirus for cancer treatment.
- Vector modifications to eliminate transposase expression following piggyBac-mediated transgenesis.
- Viruses in the treatment of brain tumors.
- [Experimental studies on human lung cancer gene-therapy with HSV-TK/GCV system].
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Keywords of People
- Chitneni, Satish K., Associate Professor in Radiology, Radiology