Thymosin
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Subject Areas on Research
- Altered levels of prothymosin immunoreactive peptide, a growth-related gene product, during liver regeneration after chronic ethanol feeding.
- Demonstration of abnormalities in expression of thymic epithelial surface antigens in severe cellular immunodeficiency diseases.
- Evaluation of skeletal and cardiac muscle function after chronic administration of thymosin beta-4 in the dystrophin deficient mouse.
- Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cell-mediated cardiac protection and functional improvement.
- Hepatic stellate cells express thymosin Beta 4 in chronically damaged liver.
- Identification of human and rodent thymic epithelium using tetanus toxin and monoclonal antibody A2B5.
- Immunoreconstitution.
- Influence of prothymosin-alpha on HIV-1 target cells.
- Monoclonal antibody against human T cell leukemia virus p19 defines a human thymic epithelial antigen acquired during ontogeny.
- Novel function of prothymosin alpha as a potent inhibitor of human immunodeficiency virus type 1 gene expression in primary macrophages.
- Phenotypic characterization and ontogeny of mesodermal-derived and endocrine epithelial components of the human thymic microenvironment.
- Prothymosin-alpha inhibits HIV-1 via Toll-like receptor 4-mediated type I interferon induction.
- Randomized trial of combined modality therapy with and without thymosin fraction V in the treatment of small cell lung cancer.
- Thymosin beta-4 regulates activation of hepatic stellate cells via hedgehog signaling.
- Thymosin fraction 5 inhibits the proliferation of the rat neuroendocrine MMQ pituitary adenoma and C6 glioma cell lines in vitro.
- Use of thymic grafts or thymic factors to augment immunologic recovery after bone marrow transplantation: brief report with 2 to 12 years' follow-up.
- c-Myc creates an activation loop by transcriptionally repressing its own functional inhibitor, hMad4, in young fibroblasts, a loop lost in replicatively senescent fibroblasts.