Thyroid Hormones

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  Subject Areas on Research

  • A critical period for the role of thyroid hormone in development of renal alpha-adrenergic receptors. 
  • A rapid cytoplasmic mechanism for PI3 kinase regulation by the nuclear thyroid hormone receptor, TRβ, and genetic evidence for its role in the maturation of mouse hippocampal synapses in vivo. 
  • Acromegaly and Cushing's syndrome associated with a foregut carcinoid tumor. 
  • Adrenergic effects on plasma lipoprotein metabolism. Speculation on mechanisms of action. 
  • An inhibitory region of the DNA-binding domain of thyroid hormone receptor blocks hormone-dependent transactivation. 
  • Analysis of thyroid hormones in serum by liquid chromatography-tandem mass spectrometry. 
  • Associations between Polybrominated Diphenyl Ether (PBDE) Flame Retardants, Phenolic Metabolites, and Thyroid Hormones during Pregnancy 
  • Associations of birth outcomes with maternal polybrominated diphenyl ethers and thyroid hormones during pregnancy. 
  • Basal and thyroid hormone receptor auxiliary protein-enhanced binding of thyroid hormone receptor isoforms to native thyroid hormone response elements. 
  • Beta-adrenergic receptors: biochemical mechanisms of physiological regulation. 
  • Cardiac alpha-adrenergic receptor expression is regulated by thyroid hormone during a critical developmental period. 
  • Changes in Hepatic TRβ Protein Expression, Lipogenic Gene Expression, and Long-Chain Acylcarnitine Levels During Chronic Hyperthyroidism and Triiodothyronine Withdrawal in a Mouse Model. 
  • Changes in Serum Calcitonin Concentrations, Incidence of Medullary Thyroid Carcinoma, and Impact of Routine Calcitonin Concentration Monitoring in the EXenatide Study of Cardiovascular Event Lowering (EXSCEL). 
  • Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism. 
  • Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism. 
  • Concentrations of perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) and their associations with human semen quality measurements. 
  • Daily physical activity is negatively associated with thyroid hormone levels, inflammation, and immune system markers among men and women in the NHANES dataset. 
  • Developmental toxicity of the PBDE metabolite 6-OH-BDE-47 in zebrafish and the potential role of thyroid receptor β. 
  • Diagnosis and treatment of hypothyroidism in the elderly. 
  • Dioxin-like activity and maternal thyroid hormone levels in second trimester maternal serum. 
  • Direct effects of thyroid hormones on hepatic lipid metabolism. 
  • Disruption of thyroid hormone sulfotransferase activity by brominated flame retardant chemicals in the human choriocarcinoma placenta cell line, BeWo. 
  • Effect of exercise and menstrual cycle status on plasma lipids, low density lipoprotein particle size, and apolipoproteins. 
  • Endocrine changes and metabolic responses in a validated canine brain death model. 
  • Estimation of energetic condition in wild baboons using fecal thyroid hormone determination. 
  • Exposure to a PBDE/OH-BDE mixture alters juvenile zebrafish (Danio rerio) development. 
  • FoxO1 deacetylation regulates thyroid hormone-induced transcription of key hepatic gluconeogenic genes. 
  • Genetic regulation of beta-adrenergic receptors. 
  • Gestational thyroid hormone concentrations and risk of attention-deficit hyperactivity disorder in the Norwegian Mother, Father and Child Cohort Study. 
  • Glycolytic reprogramming in cancer cells: PKM2 dimer predominance induced by pulsatile PFK-1 activity. 
  • Half-site arrangement of hybrid glucocorticoid and thyroid hormone response elements specifies thyroid hormone receptor complex binding to DNA and transcriptional activity. 
  • Hepatic FOXO1 Target Genes Are Co-regulated by Thyroid Hormone via RICTOR Protein Deacetylation and MTORC2-AKT Protein Inhibition. 
  • Hormonal control of angiotensinogen production. 
  • Hypothalamic insufficiency: the cause of hypopituitarism in sarcoidosis. 
  • Impacts of Unregulated Novel Brominated Flame Retardants on Human Liver Thyroid Deiodination and Sulfotransferation. 
  • Increased coiling frequency linked to apoptosis in the brain and altered thyroid signaling in zebrafish embryos (Danio rerio) exposed to the PBDE metabolite 6-OH-BDE-47. 
  • Independent signals control expression of the calcineurin inhibitory proteins MCIP1 and MCIP2 in striated muscles. 
  • Intracellular proteolytic cleavage of 9-cis-retinoic acid receptor alpha by cathepsin L-type protease is a potential mechanism for modulating thyroid hormone action. 
  • Long-term contractile activity and thyroid hormone supplementation produce engineered rat myocardium with adult-like structure and function. 
  • Loss of pyruvate kinase M2 limits growth and triggers innate immune signaling in endothelial cells. 
  • Low level exposure to the flame retardant BDE-209 reduces thyroid hormone levels and disrupts thyroid signaling in fathead minnows. 
  • Maternal Urinary Triclosan Concentration in Relation to Maternal and Neonatal Thyroid Hormone Levels: A Prospective Study. 
  • Metabolomics to Assess Thyroid Hormone Status? 
  • Microarray analysis of knockout mice identifies cyclin D2 as a possible mediator for the action of thyroid hormone during the postnatal development of the cerebellum. 
  • Mitochondrial Quality Control as a Therapeutic Target. 
  • Modulation of hepatic adrenergic receptor ontogeny by thyroid hormone. 
  • New insights into thyroid hormone action. 
  • Nonalcoholic Fatty Liver Disease and Hypercholesterolemia: Roles of Thyroid Hormones, Metabolites, and Agonists. 
  • Novel Transcriptional Mechanisms for Regulating Metabolism by Thyroid Hormone. 
  • Obligatory role of thyroid hormones in development of peripheral sympathetic and central nervous system catecholaminergic neurons: effects of propylthiouracil-induced hypothyroidism on transmitter levels, turnover and release. 
  • PBDEs Concentrate in the Fetal Portion of the Placenta: Implications for Thyroid Hormone Dysregulation. 
  • PKM1 Exerts Critical Roles in Cardiac Remodeling Under Pressure Overload in the Heart. 
  • Pediatric radiology case of the day. Congenital goiter secondary to inherited thyroid dyshormonogenesis. 
  • Perfluoroalkyl and polyfluoroalkyl substances and fetal thyroid hormone levels in umbilical cord blood among newborns by prelabor caesarean delivery. 
  • Perfluoroalkyl and polyfluroalkyl substances and maternal thyroid hormones in early pregnancy. 
  • Pharmacological Inhibition of Lysosomal Activity as a Method For Monitoring Thyroid Hormone-induced Autophagic Flux in Mammalian Cells In Vitro. 
  • Physiological and molecular basis of thyroid hormone action. 
  • Rapid method for the measurement of circulating thyroid hormones in low volumes of teleost fish plasma by LC-ESI/MS/MS. 
  • Repair-related activation of hedgehog signaling in stromal cells promotes intrahepatic hypothyroidism. 
  • Resistance to thyroid hormone in a patient without thyroid hormone receptor mutations. 
  • Role of thyroid hormone in hepatic gene regulation, chromatin remodeling, and autophagy. 
  • Role of thyroid hormone in the development of beta adrenergic control of ornithine decarboxylase in rat heart and kidney. 
  • Role of thyroid status in the ontogeny of adrenergic cell signaling in rat brain: beta receptors, adenylate cyclase, ornithine decarboxylase and c-fos protooncogene expression. 
  • The cardiac-sympathetic axis as a teratological model. 
  • The developmental switch in ventricular myosin expression in vivo is not triggered by an increase in cyclic AMP. 
  • The thermogenic effect of thyroid hormone and its clinical implications. 
  • Thermogenesis in Adipose Tissue Activated by Thyroid Hormone. 
  • Thyroid Hormone Decreases Hepatic Steatosis, Inflammation, and Fibrosis in a Dietary Mouse Model of Nonalcoholic Steatohepatitis. 
  • Thyroid Hormone Signaling Pathways: Time for a More Precise Nomenclature. 
  • Thyroid Hormones and Thyromimetics: A New Approach to Nonalcoholic Steatohepatitis? 
  • Thyroid hormone action at the cellular, genomic and target gene levels. 
  • Thyroid hormone fluctuations indicate a thermoregulatory function in both a tropical (Alouatta palliata) and seasonally cold-habitat (Macaca fuscata) primate. 
  • Thyroid hormone levels in term and preterm neonates. 
  • Thyroid hormone modulation of agonist--beta-adrenergic receptor interactions in the rat heart. 
  • Thyroid hormone negatively regulates CDX2 and SOAT2 mRNA expression via induction of miRNA-181d in hepatic cells. 
  • Thyroid hormone regulates ontogeny of beta adrenergic receptors and adenylate cyclase in rat heart and kidney: effects of propylthiouracil-induced perinatal hypothyroidism. 
  • Thyroid hormone regulation of alpha-adrenergic receptors: studies in rat myocardium. 
  • Thyroid hormone regulation of hepatic genes in vivo detected by complementary DNA microarray. 
  • Thyroid hormone regulation of hepatic lipid and carbohydrate metabolism. 
  • Thyroid hormone response elements differentially modulate the interactions of thyroid hormone receptors with two receptor binding domains in the steroid receptor coactivator-1. 
  • Thyroid hormone use during cardiac transplant organ procurement. 
  • Thyroid hormones affect recovery from depression during antidepressant treatment. 
  • Thyroid hormones and 3,5-diiodothyropropionic acid: new keys for new locks. 
  • Thyroid toxicity due to subchronic exposure to a complex mixture of 16 organochlorines, lead, and cadmium. 
  • Tissue distribution and thyroid hormone effects on mRNA abundance for membrane transporters Mct8, Mct10, and organic anion-transporting polypeptides (Oatps) in a teleost fish. 
  • Umbilical cord thiocyanate and thyroid function in intrauterine growth-restricted infants of the smoking gravida. 
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  Keywords of People

  • Pang, Herbert, Adjunct Assistant Professor in the Department of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics