Trachea

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  Subject Areas on Research

  • A biomimetic multicellular model of the airways using primary human cells. 
  • A comparative analysis of marine mammal tracheas. 
  • A comparison of a silicone wire-reinforced tube with the Parker and polyvinyl chloride tubes for tracheal intubation through an intubating laryngeal mask airway in patients with normal airways undergoing general anesthesia. 
  • A genome-wide analysis of open chromatin in human tracheal epithelial cells reveals novel candidate regulatory elements for lung function. 
  • A method for preventing endotracheal tube cuff overdistention caused by nitrous oxide diffusion. 
  • A revised airway epithelial hierarchy includes CFTR-expressing ionocytes. 
  • A role for sonic hedgehog signaling in the pathogenesis of human tracheoesophageal fistula. 
  • Accuracy of the 7-8-9 Rule for endotracheal tube placement in the neonate. 
  • Activated armadillo/beta-catenin does not play a general role in cell migration and process extension in Drosophila. 
  • Acute external laryngotracheal trauma: diagnosis and management. 
  • Age-related changes in the cellular composition and epithelial organization of the mouse trachea. 
  • Airway smooth muscle dysfunction in Pompe (Gaa-/- ) mice. 
  • Allograft airway fibrosis in the pulmonary milieu: a disorder of tissue remodeling. 
  • An unusual presentation of an airway tear. 
  • Assessing oropharyngeal dysphagia after lung transplantation: altered swallowing mechanisms and increased morbidity. 
  • BMP antagonism by Noggin is required in presumptive notochord cells for mammalian foregut morphogenesis. 
  • BMP signaling and cellular dynamics during regeneration of airway epithelium from basal progenitors. 
  • BOugie or stylet in patients UnderGoing Intubation Emergently (BOUGIE): protocol and statistical analysis plan for a randomised clinical trial. 
  • Basal cells as stem cells of the mouse trachea and human airway epithelium. 
  • Beta-arrestins specifically constrain beta2-adrenergic receptor signaling and function in airway smooth muscle. 
  • Bilateral Upper Lobe Bronchi Originating from the Trachea. 
  • Biofilm accumulation on endotracheal tubes following prolonged intubation. 
  • Blunt tracheobronchial injuries: treatment and outcomes. 
  • Bronchodilator S-nitrosothiol deficiency in asthmatic respiratory failure. 
  • Bronchoscopy-guided transtracheal and transbronchial fine-needle aspiration biopsy: a 5-year institutional review of 111 cases. 
  • Building organs from buds, branches and tubes. 
  • Carbohydrate histochemistry of surface epithelium of rat trachea: backscatter and x-ray imaging. 
  • Carcinogen-induced unscheduled DNA synthesis in xenotransplanted human tracheobronchial epithelium: comparison with rat tracheal epithelium. 
  • Cholinergic mechanisms involved with histamine hyperreactivity in immune rabbit airways challenged with ragweed antigen. 
  • Chondrogenesis by free and vascularized rabbit auricular perichondrium. 
  • Ciliated epithelial cell lifespan in the mouse trachea and lung. 
  • Clinical considerations for blunt laryngotracheal trauma in children. 
  • Coblation of suprastomal granulomas in tracheostomy-dependent children. 
  • Combined anatomical optical coherence tomography and intraluminal pressure reveal viscoelasticity of the in vivo airway. 
  • Combined systemic and mucosal immunization with microsphere-encapsulated inactivated simian immunodeficiency virus elicits serum, vaginal, and tracheal antibody responses in female rhesus macaques. 
  • Compartmentalization of the foregut tube: developmental origins of the trachea and esophagus. 
  • Complete disruption of right main bronchus: a case report and literature review. 
  • Composite tissue allotransplantation: current challenges. 
  • Concurrent production of reactive oxygen and nitrogen species by airway epithelial cells in vitro. 
  • Cost and time savings following introduction of rejection criteria for clinical specimens. 
  • Current management of laryngotracheal trauma: case report and literature review. 
  • Defective innate immunity and hyperinflammation in newborn cystic fibrosis transmembrane conductance regulator-knockout ferret lungs. 
  • Dehydroepiandrosterone and analogs inhibit DNA binding of AP-1 and airway smooth muscle proliferation. 
  • Determinants of tracheobronchial histologic alterations during conventional mechanical ventilation. 
  • Development of a citric acid aerosol as a smoking cessation aid. 
  • Development of a tracheal implant xenograft model to expose human bronchial epithelial cells to toxic gases. 
  • Developmental expression of neurokinin A and functional neurokinin-2 receptors in lung. 
  • Different high-frequency ventilator strategies: effect on the propagation of tracheobronchial histopathologic changes. 
  • Different ontogeny of rate of force generation and shortening velocity in guinea pig trachealis. 
  • Dorso-ventral heterogeneity in tracheal basal stem cells. 
  • Effect of allergic bronchoconstriction on airways epithelial permeability to large polar solutes in the guinea pig. 
  • Effect of cooling on the responsiveness of canine tracheal muscle. 
  • Effect of intraoperative ischemia on chondrogenesis by vascularized auricular perichondrium grafted in the airway. 
  • Effect of lidocaine on endothelin-1-mediated airway smooth muscle contraction in the rat trachea. 
  • Effect of maturational changes in myosin content and morphometry on airway smooth muscle contraction. 
  • Effect of substance P on neurally mediated contraction of rabbit airway smooth muscle. 
  • Effects of temperature on cholinergic contractility of rabbit airway muscle. 
  • Elective Venovenous Extracorporeal Membrane Oxygenation for Resection of Endotracheal Tumor: A Case Report. 
  • Emergent thoracotomy for airway control after intrathoracic tracheal injury. 
  • Endotracheal artificial larynx. 
  • Endotracheal flumazenil: a new route of administration for benzodiazepine antagonism. 
  • Epithelial stem cells of the lung: privileged few or opportunities for many? 
  • Epithelial stem/progenitor cells in lung postnatal growth, maintenance, and repair. 
  • Evaluating laryngotracheal stenosis in a canine model with virtual bronchoscopy. 
  • Expression of airway contractile properties and acetylcholinesterase activity in swine. 
  • Extracellular Ca2+ mobilization in potential-dependent contraction of trachealis of maturing swine. 
  • Extrinsic coagulation blockade attenuates lung injury and proinflammatory cytokine release after intratracheal lipopolysaccharide. 
  • Fibroblast growth factor signaling in the developing tracheoesophageal fistula. 
  • Focal abnormalities of the trachea and main bronchi. 
  • G protein-coupled receptor kinase 5 regulates airway responses induced by muscarinic receptor activation. 
  • Healing of a free tracheal autograft is enhanced by topical vascular endothelial growth factor in an experimental rabbit model. 
  • Hepatic microsomal phospholipids in rats exposed intratracheally to coal fly ash. 
  • Hyperbaric tracheobronchial compression in cetaceans and pinnipeds. 
  • Hypersecretion of mucin in response to inflammatory mediators by guinea pig tracheal epithelial cells in vitro is blocked by inhibition of nitric oxide synthase. 
  • IL-6/STAT3 promotes regeneration of airway ciliated cells from basal stem cells. 
  • Immune cells in a mouse airway model of obliterative bronchiolitis. 
  • Immunohistologic quantification of Pseudomonas aeruginosa in the tracheobronchial tree from patients with cystic fibrosis. 
  • In situ assessment of intraepithelial neoplasia in hamster trachea epithelium using angle-resolved low-coherence interferometry. 
  • Intercellular growth factor signaling and the development of mouse tracheal submucosal glands. 
  • Laryngeal and tracheal anomalies in an infant with oral-facial-digital syndrome type VI (Váradi-Papp): report of a transitional type. 
  • Laryngeal transplantation and 40-month follow-up. 
  • Laryngotracheal foreign bodies in children. A comparison with bronchial foreign bodies. 
  • Length oscillation induces force potentiation in infant guinea pig airway smooth muscle. 
  • Loss of basal cells precedes bronchiolitis obliterans-like pathological changes in a murine model of chlorine gas inhalation. 
  • Maturation of acetylcholinesterase expression in tracheal smooth muscle contraction. 
  • Maturation of guinea pig tracheal strip stiffness. 
  • Maturation of neuromodulatory effect of substance P in rabbit airways. 
  • Maturational changes in airway smooth muscle shortening and relaxation. Implications for asthma. 
  • Mechanisms of airway hypercontractility in basenji-greyhound dogs. 
  • Mechanisms of substance P-induced contraction of rabbit airway smooth muscle. 
  • Morphogenesis of the trachea and esophagus: current players and new roles for noggin and Bmps. 
  • Multiple roles for Sox2 in the developing and adult mouse trachea. 
  • Neurokinin receptors mediating substance P-induced contraction in adult rabbit airways. 
  • Neurokinin subtype receptors mediating substance P contraction in immature rabbit airways. 
  • Neuromodulation mediated by neurokinin-1 subtype receptors in adult rabbit airways. 
  • Neutralizing antibody vaccine for pandemic and pre-emergent coronaviruses. 
  • Nonoperative management of postintubation tracheal injuries. 
  • Novel Airway and Ventilator Management of Tracheobronchial Disruption After Blunt Trauma. 
  • On the terminology for describing the length-force relationship and its changes in airway smooth muscle. 
  • One shall become two: Separation of the esophagus and trachea from the common foregut tube. 
  • Ontogenesis of myosin light chain kinase mRNA and protein content in guinea pig tracheal smooth muscle. 
  • Ontogenesis of myosin light chain phosphorylation in guinea pig tracheal smooth muscle. 
  • Ontogenic expression of acetylcholinesterase activity in trachealis of young swine. 
  • Ontogeny of shortening velocity in porcine trachealis. 
  • Optoacoustic Evaluation of Endotracheal Tube Depth in Pediatrics. 
  • Outcomes of tracheobronchial stents in patients with malignant airway disease. 
  • Oxidant stress stimulates mucin secretion and PLC in airway epithelium via a nitric oxide-dependent mechanism. 
  • PAF-induced contraction of canine trachea mediated by 5-hydroxytryptamine in vivo. 
  • Parent stem cells can serve as niches for their daughter cells. 
  • Pericyte requirement for anti-leak action of angiopoietin-1 and vascular remodeling in sustained inflammation. 
  • Persistent endotracheal tube cuff overdistension: a sign of tracheomalacia. 
  • Perspective volume rendering of CT and MR images: applications for endoscopic imaging. 
  • Physiological mechanisms mediating enhanced force generation during development and immune sensitization. 
  • Potentiation of vagal contractile response by thromboxane mimetic U-46619. 
  • Protection from experimental asthma by an endogenous bronchodilator. 
  • Protein kinase C and Ca2+ activation of mucin secretion in airway goblet cells. 
  • Protein phosphorylation responses in normal and cystic fibrosis airway epithelial cell lines. 
  • Pulmonary hemodynamic consequences of ECG-synchronized ventilation. 
  • Quantification of beta adrenergic receptor subtypes in beta-arrestin knockout mouse airways. 
  • Radiation-induced narrowing of the tracheobronchial tree: an in-depth analysis. 
  • Radiographic appearance of the Lanz tracheal tube. 
  • Radiographic features of mediastinal anatomy. 
  • Radiology quiz case 1. Tracheocele. 
  • Rapacuronium augments acetylcholine-induced bronchoconstriction via positive allosteric interactions at the M3 muscarinic receptor. 
  • Reconstruction of the rabbit trachea with vascularized auricular perichondrium. 
  • Recurrent arteriotracheal fistula. 
  • Reduced spontaneous relaxation in immature guinea pig airway smooth muscle is associated with increased prostanoid release. 
  • Rejection criteria for endotracheal aspirates from adults. 
  • Rejection criteria for endotracheal aspirates from pediatric patients. 
  • Rejection criteria for endotracheal aspirates. 
  • Relaxation of guinea pig trachealis during electrical field stimulation increases with age. 
  • Repair and regeneration of the respiratory system: complexity, plasticity, and mechanisms of lung stem cell function. 
  • Requirement for reactive oxygen species in serum-induced and platelet-derived growth factor-induced growth of airway smooth muscle. 
  • Saddle nose, red ears, and fatal airway collapse. Relapsing polychondritis. 
  • Salvage Cryoablation for Local Recurrences of Thyroid Cancer Inseparable from the Trachea and Neurovascular Structures. 
  • Sensing Inhalation Injury-Associated Changes in Airway Wall Compliance by Anatomic Optical Coherence Elastography. 
  • Short trachea and endotracheal tube placement. 
  • Spatially resolved measurements of hyperpolarized gas properties in the lung in vivo. Part II: T *(2). 
  • Spiracular fluttering increases oxygen uptake 
  • Study of gastric fluid induced cytokine and chemokine expression in airway smooth muscle cells and airway remodeling. 
  • Subjective response to cigarette smoking following airway anesthetization. 
  • Successful combined surgical approach in a rare case of retrotracheal goitre in a patient with anatomical impediments. 
  • Synthesis and NK(1)/NK(2) binding activities of a series of diacyl-substituted 2-arylpiperazines. 
  • TRPV4 channel participates in receptor-operated calcium entry and ciliary beat frequency regulation in mouse airway epithelial cells. 
  • The "High-Riding" superior pericardial recess: CT findings. 
  • The novel use of computer-generated virtual imaging to assess the difficult pediatric airway. 
  • The regulation of the cGMP-binding cGMP phosphodiesterase by proteins that are immunologically related to gamma subunit of the photoreceptor cGMP phosphodiesterase. 
  • The role of Scgb1a1+ Clara cells in the long-term maintenance and repair of lung airway, but not alveolar, epithelium. 
  • The role of upper airway stimulation in smoking. 
  • The use of tracheal implants in toxicology and carcinogenesis research. 
  • Too big to fail?-An aggressive strategy for a dire problem. 
  • Tracheal compression delays alveolar collapse during deep diving in marine mammals. 
  • Tracheal surgery for airway anomalies associated with increased mortality in pediatric patients undergoing heart surgery: Society of Thoracic Surgeons Database analysis. 
  • Tracheobronchial mucoid pseudotumors. 
  • Tracheobronchial trauma associated with airway management in neonates. 
  • Tracheoscopy with the rapiscope to verify endotracheal tube placement. 
  • Transformation of rat tracheal epithelial cells to immortal growth variants by particulate and soluble nickel compounds. 
  • Tumor necrosis factor-alpha stimulates mucin secretion and cyclic GMP production by guinea pig tracheal epithelial cells in vitro. 
  • Ultrastructural morphology of the lung in cystic fibrosis. 
  • Vagal innervation is required for pulmonary function phenotype in Htr4-/- mice. 
  • Variable levels of normal RNA in different fetal organs carrying a cystic fibrosis transmembrane conductance regulator splicing mutation. 
  • Vascularized auricular perichondrium in airway reconstruction: the effects of stenting with and without a mucosal graft. 
  • Virtual bronchoscopy for directing transbronchial needle aspiration of hilar and mediastinal lymph nodes: a pilot study. 
  • Voice rehabilitation after total laryngectomy and tracheoesophageal puncture using nonmuscle closure. 
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  Keywords of People

  • Driehuys, Bastiaan, Professor of Radiology, Biomedical Engineering
  • Esclamado, Ramon Mitra, Richard Hall Chaney, Sr. Distinguished Professor Emeritus of Otolaryngology, Head and Neck Surgery & Communication Sciences
  • Hogan, Brigid L. M., Research Professor of Cell Biology, Cell Biology
  • Lee, Walter T, Professor of Head and Neck Surgery & Communication Sciences, Radiation Oncology
  • Raynor, Eileen Margolies, Associate Professor of Head and Neck Surgery & Communication Sciences, Pediatrics
  • Sunday, Mary Elizabeth Anne, Professor of Pathology, Cell Biology