Transcription, Genetic

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  Subject Areas on Research

  • 'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR. 
  • (Pro)renin receptor is expressed in human retinal pigment epithelium and participates in extracellular matrix remodeling. 
  • 16 alpha-substituted analogs of the antiprogestin RU486 induce a unique conformation in the human progesterone receptor resulting in mixed agonist activity. 
  • 27-Hydroxycholesterol: a potential endogenous regulator of estrogen receptor signaling. 
  • 27-hydroxycholesterol is an endogenous selective estrogen receptor modulator. 
  • 3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro. 
  • A 30-kDa alternative translation product of the CCAAT/enhancer binding protein alpha message: transcriptional activator lacking antimitotic activity. 
  • A 40-kilodalton protein binds specifically to an upstream sequence element essential for muscle-specific transcription of the human myoglobin promoter. 
  • A 6-Mb high-resolution physical and transcription map encompassing the hereditary prostate cancer 1 (HPC1) region. 
  • A BMP pathway regulates cell fate allocation along the sea urchin animal-vegetal embryonic axis. 
  • A CNS catecholaminergic cell line expresses voltage-gated currents. 
  • A CaMK cascade activates CRE-mediated transcription in neurons of Caenorhabditis elegans. 
  • A Drosophila CREB/CREM homolog encodes multiple isoforms, including a cyclic AMP-dependent protein kinase-responsive transcriptional activator and antagonist. 
  • A Functional Polymorphism (rs2494752) in the AKT1 Promoter Region and Gastric Adenocarcinoma Risk in an Eastern Chinese Population. 
  • A Lamina-Associated Domain Border Governs Nuclear Lamina Interactions, Transcription, and Recombination of the Tcrb Locus. 
  • A Mep2-dependent transcriptional profile links permease function to gene expression during pseudohyphal growth in Saccharomyces cerevisiae. 
  • A Molecular Switch Regulating Cell Fate Choice between Muscle Progenitor Cells and Brown Adipocytes. 
  • A Novel Mycovirus Evokes Transcriptional Rewiring in the Fungus Malassezia and Stimulates Beta Interferon Production in Macrophages. 
  • A T cell-specific transcriptional enhancer within the human T cell receptor delta locus. 
  • A Xenopus egg factor with DNA-binding properties characteristic of terminus-specific telomeric proteins. 
  • A cAMP response element in the beta 2-adrenergic receptor gene confers transcriptional autoregulation by cAMP. 
  • A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type. 
  • A case study of the reproducibility of transcriptional reporter cell-based RNAi screens in Drosophila. 
  • A cis-acting sequence homologous to the yeast filamentation and invasion response element regulates expression of a pectinase gene from the bean pathogen Colletotrichum lindemuthianum. 
  • A combinatorial mechanism for determining the specificity of E2F activation and repression. 
  • A complex intronic enhancer regulates expression of the CFTR gene by direct interaction with the promoter. 
  • A comprehensive structure-function analysis of Arabidopsis SNI1 defines essential regions and transcriptional repressor activity. 
  • A connection between stress and development in the multicellular prokaryote Streptomyces coelicolor A3(2). 
  • A conserved sorting-associated protein is mutant in chorea-acanthocytosis. 
  • A direct link between carbohydrate utilization and virulence in the major human pathogen group A Streptococcus. 
  • A fluorogenic C. neoformans reporter strain with a robust expression of m-cherry expressed from a safe haven site in the genome. 
  • A gene atlas of the mouse and human protein-encoding transcriptomes. 
  • A genomic approach to identify regulatory nodes in the transcriptional network of systemic acquired resistance in plants. 
  • A genomic- and proteomic-based hypothesis on the eclectic effects of systemic interleukin-2 administration in the context of melanoma-specific immunization. 
  • A human protein related to yeast Cdc6p. 
  • A light-inducible CRISPR-Cas9 system for control of endogenous gene activation. 
  • A link between breast cancer and local estrogen biosynthesis suggested by quantification of breast adipose tissue aromatase cytochrome P450 transcripts using competitive polymerase chain reaction after reverse transcription. 
  • A mechanism of COOH-terminal binding protein-mediated repression. 
  • A method for analysis of gene expression patterns. 
  • A molecular mechanism for the differential regulation of TGF-beta1 expression due to the common SNP -509C-T (c. -1347C > T). 
  • A mouse homologue of FAST-1 transduces TGF beta superfamily signals and is expressed during early embryogenesis. 
  • A mutation in the largest subunit of RNA polymerase II alters RNA chain elongation in vitro. 
  • A naturally occurring gamma globin gene mutation enhances SP1 binding activity. 
  • A negative coregulator for the human ER. 
  • A novel activation pathway for mature thymocytes. Costimulation of CD2 (T,p50) and CD28 (T,p44) induces autocrine interleukin 2/interleukin 2 receptor-mediated cell proliferation. 
  • A novel basal promoter element is required for expression of the rat tyrosine hydroxylase gene. 
  • A novel domain in Set2 mediates RNA polymerase II interaction and couples histone H3 K36 methylation with transcript elongation. 
  • A paired-end sequencing strategy to map the complex landscape of transcription initiation. 
  • A pathway of neuronal apoptosis induced by hypoxia/reoxygenation: roles of nuclear factor-kappaB and Bcl-2. 
  • A phosphorylated cytoplasmic autoantigen, GW182, associates with a unique population of human mRNAs within novel cytoplasmic speckles. 
  • A polymorphism of the human matrix gamma-carboxyglutamic acid protein promoter alters binding of an activating protein-1 complex and is associated with altered transcription and serum levels. 
  • A precisely regulated gene expression cassette potently modulates metastasis and survival in multiple solid cancers. 
  • A predictive model for transcriptional control of physiology in a free living cell. 
  • A promoter deletion reduces the rate of mitotic, but not meiotic, recombination at the HIS4 locus in yeast. 
  • A recombination-based assay demonstrates that the fragile X sequence is transcribed widely during development. 
  • A role for TREK1 in generating the slow afterhyperpolarization in developing starburst amacrine cells. 
  • A role for cohesin in T-cell-receptor rearrangement and thymocyte differentiation. 
  • A role for nuclear inositol 1,4,5-trisphosphate kinase in transcriptional control. 
  • A signaling complex of Ca2+-calmodulin-dependent protein kinase IV and protein phosphatase 2A. 
  • A single base substitution in the variable pocket of yeast tRNA(Arg) eliminates species-specific aminoacylation. 
  • A small interfering RNA screen for modulators of tumor cell motility identifies MAP4K4 as a promigratory kinase. 
  • A small regulatory element from chromosome 19 enhances liver-specific gene expression. 
  • A specialized nucleosome modulates transcription factor access to a C. glabrata metal responsive promoter. 
  • A specific 31-nucleotide domain of U1 RNA directly interacts with the 70K small nuclear ribonucleoprotein component. 
  • A standardized approach to PCR-based semiquantitation of multiple cytokine gene transcripts from small cell samples. 
  • A study of the repetitive structure and distribution of short motifs in human genomic sequences. 
  • A surface of Escherichia coli sigma 70 required for promoter function and antitermination by phage lambda Q protein. 
  • A susceptibility gene for affective disorders and the response of the human amygdala. 
  • A targeted analysis reveals relevant shifts in the methylation and transcription of genes responsible for bile acid homeostasis and drug metabolism in non-alcoholic fatty liver disease. 
  • A three-dimensional culture system recapitulates placental syncytiotrophoblast development and microbial resistance. 
  • A transcription factor affinity-based code for mammalian transcription initiation. 
  • A transcription network of interlocking positive feedback loops maintains intracellular iron balance in archaea. 
  • A transcriptional signature accurately identifies Aspergillus Infection across healthy and immunosuppressed states. 
  • A truncated form of fibroblast growth factor receptor 1 inhibits signal transduction by multiple types of fibroblast growth factor receptor. 
  • A variant in the CHEK2 promoter at a methylation site relieves transcriptional repression and confers reduced risk of lung cancer. 
  • A20 modulates lipid metabolism and energy production to promote liver regeneration. 
  • ABL1 promoter methylation can exist independently of BCR-ABL transcription in chronic myeloid leukemia hematopoietic progenitors. 
  • AP-1 subunits converge promiscuously at enhancers to potentiate transcription. 
  • ARID1A-mutated ovarian cancers depend on HDAC6 activity. 
  • AT2 receptor and vascular smooth muscle cell differentiation in vascular development. 
  • Abasic sites in the transcribed strand of yeast DNA are removed by transcription-coupled nucleotide excision repair. 
  • Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease. 
  • Acidic stress promotes a glioma stem cell phenotype. 
  • Actions of steroids in mitochondria. 
  • Activated cAMP-response element-binding protein regulates neuronal expression of presenilin-1. 
  • Activation and repression of mammalian gene expression by the c-myc protein. 
  • Activation of MEF2 by muscle activity is mediated through a calcineurin-dependent pathway. 
  • Activity of a Py-Im polyamide targeted to the estrogen response element. 
  • Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance. 
  • Addressing biological uncertainties in engineering gene circuits. 
  • Adenovirus-mediated expression of the catalytic subunit of glucose-6-phosphatase in INS-1 cells. Effects on glucose cycling, glucose usage, and insulin secretion. 
  • Adrenergic Stimulation of DUSP1 Impairs Chemotherapy Response in Ovarian Cancer. 
  • Agonist-induced sensitization of beta-adrenoceptor signaling in neonatal rat heart: expression and catalytic activity of adenylyl cyclase. 
  • All cyclophilins and FK506 binding proteins are, individually and collectively, dispensable for viability in Saccharomyces cerevisiae. 
  • Allelic loss at the tuberous sclerosis 2 locus in spontaneous tumors in the Eker rat. 
  • Alpha-fetoprotein-specific genetic immunotherapy for hepatocellular carcinoma. 
  • Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients. 
  • Altered intragraft immune responses and improved renal function in MHC class II-deficient mouse kidney allografts. 
  • Alternative activation of extracellular signal-regulated protein kinases in curcumin and arsenite-induced HSP70 gene expression in human colorectal carcinoma cells. 
  • Alternative processing of androgen-binding protein RNA transcripts in fetal rat liver. Identification of a transcript formed by trans splicing. 
  • Alternative splicing: a mechanism for phenotypic rescue of a common inherited defect. 
  • Alternative translation initiation site usage results in two structurally distinct forms of Pit-1. 
  • Alternative translation of osteopontin generates intracellular and secreted isoforms that mediate distinct biological activities in dendritic cells. 
  • Alu RNA-protein complexes formed in vitro react with a novel lupus autoantibody. 
  • An activity necessary for in vitro transcription is a DNase inhibitor. 
  • An enhancer-blocking element between alpha and delta gene segments within the human T cell receptor alpha/delta locus. 
  • An essential role for Mad homology domain 1 in the association of Smad3 with histone deacetylase activity*. 
  • An evolutionarily conserved mechanism delimiting SHR movement defines a single layer of endodermis in plants. 
  • An integrated encyclopedia of DNA elements in the human genome. 
  • An intron facilitates activation of the calspermin gene by the testis-specific transcription factor CREM tau. 
  • Anabolic function of the type II isozyme of hexokinase in hepatic lipid synthesis. 
  • Analyses of promoter-proximal pausing by RNA polymerase II on the hsp70 heat shock gene promoter in a Drosophila nuclear extract. 
  • Analysis of expression of multiple genes encoding calmodulin during spermatogenesis. 
  • Analysis of the individual regulatory components of the IncFII plasmid replication control system. 
  • Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. 
  • Analysis of the mouse transcriptome for genes involved in the function of the nervous system. 
  • Analysis of the role of E2A-encoded proteins in insulin gene transcription. 
  • Analysis of trans-acting response decoy RNA-mediated inhibition of human immunodeficiency virus type 1 transactivation. 
  • Analysis of transcriptome complexity through RNA sequencing in normal and failing murine hearts. 
  • Ancient polymorphism and functional variation in the primate MHC-DQA1 5' cis-regulatory region. 
  • Androgen receptor variant-driven prostate cancer: clinical implications and therapeutic targeting. 
  • Angiotensin II induces c-fos expression in smooth muscle via transcriptional control. 
  • Angiotensin II responses in AT1A receptor-deficient mice: a role for AT1B receptors in blood pressure regulation. 
  • Angiotensin II-induced hypertrophy of rat vascular smooth muscle is associated with increased 18 S rRNA synthesis and phosphorylation of the rRNA transcription factor, upstream binding factor. 
  • Antagonism between apolipoprotein AI regulatory protein 1, Ear3/COUP-TF, and hepatocyte nuclear factor 4 modulates apolipoprotein CIII gene expression in liver and intestinal cells. 
  • Antiestrogen can establish nonproductive receptor complexes and alter chromatin structure at target enhancers. 
  • Antitermination by bacteriophage lambda Q protein. 
  • Antitumorigenesis of antioxidants in a transgenic Rac1 model of Kaposi's sarcoma. 
  • Antiviral activity of mismatched double-stranded RNA against human immunodeficiency virus in vitro. 
  • Apoptosis in atretic ovarian follicles is associated with selective decreases in messenger ribonucleic acid transcripts for gonadotropin receptors and cytochrome P450 aromatase. 
  • Application of random peptide phage display to the study of nuclear hormone receptors. 
  • Arabidopsis BRCA2 and RAD51 proteins are specifically involved in defense gene transcription during plant immune responses. 
  • Arabidopsis SNI1 and RAD51D regulate both gene transcription and DNA recombination during the defense response. 
  • Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF. 
  • Aromatic hydrocarbon receptor interaction with the retinoblastoma protein potentiates repression of E2F-dependent transcription and cell cycle arrest. 
  • Ascorbic acid modulates collagen type I gene expression by cells from an eye tissue--trabecular meshwork. 
  • Aspartate release and signalling in the hippocampus. 
  • Association between a functional serotonin transporter promoter polymorphism and citalopram treatment in adult outpatients with major depression. 
  • Association of a functional tandem repeats in the downstream of human telomerase gene and lung cancer. 
  • Association of heat shock proteins with all-cause mortality. 
  • Association of increased spontaneous mutation rates with high levels of transcription in yeast. 
  • Augmentation of cardiac contractility mediated by the human beta(3)-adrenergic receptor overexpressed in the hearts of transgenic mice. 
  • Axotomy-induced regulation of c-Jun expression in regenerating rat retinal ganglion cells. 
  • BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8+ T cells. 
  • BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner. 
  • BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein. 
  • BET Bromodomain Inhibition Promotes Anti-tumor Immunity by Suppressing PD-L1 Expression. 
  • Baby Genomics: Tracing the Evolutionary Changes That Gave Rise to Placentation. 
  • Bacterial expression vectors for calmodulin. 
  • Bacterial infection of osteoblasts induces interleukin-1beta and interleukin-18 transcription but not protein synthesis. 
  • Bacterial lipids: metabolism and membrane homeostasis. 
  • Bacteriophage T4 initiates bidirectional DNA replication through a two-step process. 
  • BayFish: Bayesian inference of transcription dynamics from population snapshots of single-molecule RNA FISH in single cells. 
  • Beta-adrenergic receptors in hamster smooth muscle cells are transcriptionally regulated by glucocorticoids. 
  • Beta-catenin is a mediator of the response of fibroblasts to irradiation. 
  • Beta-catenin signaling pathway is crucial for bone morphogenetic protein 2 to induce new bone formation. 
  • Beyond intuitive modeling: combining biophysical models with innovative experiments to move the circadian clock field forward. 
  • Binary Fate Choice between Closely Related Interneuronal Types Is Determined by a Fezf1-Dependent Postmitotic Transcriptional Switch. 
  • Binding of HMG-I(Y) elicits structural changes in a silencer of the human beta-globin gene. 
  • Binding of the global response regulator protein CovR to the sag promoter of Streptococcus pyogenes reveals a new mode of CovR-DNA interaction. 
  • Biochemistry. A glucose-to-gene link. 
  • Biological functions and transcriptional targets of CaRF in neurons. 
  • Biosynthesis and in vivo localization of the decapentaplegic-Vg-related protein, DVR-6 (bone morphogenetic protein-6). 
  • Bombesin and [Leu8]phyllolitorin promote fetal mouse lung branching morphogenesis via a receptor-mediated mechanism. 
  • Brain-specific polyA- transcripts are detected in polyA+ RNA: do complex polyA- brain RNAs really exist? 
  • Branching process deconvolution algorithm reveals a detailed cell-cycle transcription program. 
  • Broad H3K4me3 is associated with increased transcription elongation and enhancer activity at tumor-suppressor genes. 
  • CAF-mediated human immunodeficiency virus (HIV) type 1 transcriptional inhibition is distinct from alpha-defensin-1 HIV inhibition. 
  • CBF, Myb, and Ets binding sites are important for activity of the core I element of the murine retrovirus SL3-3 in T lymphocytes. 
  • CCI-779 inhibits cell-cycle G2-M progression and invasion of castration-resistant prostate cancer via attenuation of UBE2C transcription and mRNA stability. 
  • CD25+CD4+ regulatory T cell migration requires L-selectin expression: L-selectin transcriptional regulation balances constitutive receptor turnover. 
  • CD30-activation-mediated growth inhibition of anaplastic large-cell lymphoma cell lines: apoptosis or cell-cycle arrest? 
  • CD8+ T cell-mediated suppressive activity inhibits HIV-1 after virus entry with kinetics indicating effects on virus gene expression. 
  • CD8+ T lymphocyte-mediated inhibition of HIV-1 long terminal repeat transcription: a novel antiviral mechanism. 
  • CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity. 
  • CIP2A mediates erlotinib-induced apoptosis in non-small cell lung cancer cells without EGFR mutation. 
  • CTLA-4-Mediated inhibition of early events of T cell proliferation. 
  • Ca2+/calmodulin-dependent protein kinase IV and calcium signaling. 
  • Calcineurin colocalizes with P-bodies and stress granules during thermal stress in Cryptococcus neoformans. 
  • Calcineurin enhances acetylcholinesterase mRNA stability during C2-C12 muscle cell differentiation. 
  • Calcineurin is required for hyphal elongation during mating and haploid fruiting in Cryptococcus neoformans. 
  • Calcium ions positively modulate follicle-stimulating hormone- and exogenous cyclic 3',5'-adenosine monophosphate-driven transcription of the P450(scc) gene in porcine granulosa cells. 
  • Calcium-sensing receptor activation of rho involves filamin and rho-guanine nucleotide exchange factor. 
  • Calmodulin-dependent protein kinase IV regulates nuclear export of Cabin1 during T-cell activation. 
  • Calspermin gene transcription is regulated by two cyclic AMP response elements contained in an alternative promoter in the calmodulin kinase IV gene. 
  • Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex. 
  • Casein kinase Iepsilon plays a functional role in the transforming growth factor-beta signaling pathway. 
  • Cell cycle-dependent expression of thyroid hormone receptor-beta is a mechanism for variable hormone sensitivity. 
  • Cell identity mediates the response of Arabidopsis roots to abiotic stress. 
  • Cell identity regulators link development and stress responses in the Arabidopsis root. 
  • Cell surface GRP78 signaling: An emerging role as a transcriptional modulator in cancer. 
  • Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms. 
  • Cell-type specific and combinatorial usage of diverse transcription factors revealed by genome-wide binding studies in multiple human cells. 
  • Cellular and molecular responses of the uterus to embryo implantation can be elicited by locally applied growth factors. 
  • Cellular mechanisms which distinguish between hormone- and antihormone-activated estrogen receptor. 
  • Changes in the expression of transcription factors ATF-2 and Fra-2 after axotomy and during regeneration in rat retinal ganglion cells. 
  • Characterization and expression of a rice RAD23 gene. 
  • Characterization of Ca2+/calmodulin-dependent protein kinase IV. Role in transcriptional regulation. 
  • Characterization of a cholesterol response element (CRE) in the promoter of the cholesteryl ester transfer protein gene: functional role of the transcription factors SREBP-1a, -2, and YY1. 
  • Characterization of a male-predominant antisense transcript underexpressed in hybrids of Drosophila pseudoobscura and D. persimilis. 
  • Characterization of kinectin, a kinesin-binding protein: primary sequence and N-terminal topogenic signal analysis. 
  • Characterization of short range DNA looping in endotoxin-mediated transcription of the murine inducible nitric-oxide synthase (iNOS) gene. 
  • Characterization of the mouse FTZ-F1 gene, which encodes a key regulator of steroid hydroxylase gene expression. 
  • Characterization of the mouse transforming growth factor alpha gene: its expression during eyelid development and in waved 1 tissues. 
  • Characterization of the rat type III hexokinase gene promoter. A functional octamer 1 motif is critical for basal promoter activity. 
  • Checkpoints couple transcription network oscillator dynamics to cell-cycle progression. 
  • Chemically induced proximity in biology and medicine. 
  • Chemoattractant-induced activation of c-fos gene expression in human monocytes. 
  • Chicken calmodulin promoter activity in proliferating and differentiated cells. 
  • Chromatin Dynamics and the Development of the TCRα and TCRδ Repertoires. 
  • Chromatin accessibility reveals insights into androgen receptor activation and transcriptional specificity. 
  • Chromatin-bound p53 anchors activated Smads and the mSin3A corepressor to confer transforming-growth-factor-beta-mediated transcription repression. 
  • Chromosomal translocation in a human leukemic stem-cell line disrupts the T-cell antigen receptor delta-chain diversity region and results in a previously unreported fusion transcript. 
  • Chronic N(G)-nitro-L-arginine methyl ester-induced hypertension : novel molecular adaptation to systolic load in absence of hypertrophy. 
  • Chronic cocaine administration increases CNS tyrosine hydroxylase enzyme activity and mRNA levels and tryptophan hydroxylase enzyme activity levels. 
  • Circadian clock-controlled genes isolated from Neurospora crassa are late night- to early morning-specific. 
  • Clonal expansion and decreased occurrence of peripheral blood gamma delta T cells of the V delta 2J delta 3 lineage in multiple sclerosis patients. 
  • Cloning and characterization of rat-brain-specific transcripts: rare, brain-specific transcripts and tyrosine hydroxylase. 
  • Cloning and expression of a human kidney cDNA for an alpha 2-adrenergic receptor subtype. 
  • Cloning and expression of full-length cDNA encoding human vitamin D receptor. 
  • Cloning and molecular characterization of a cDNA clone to statin, a protein specifically expressed in nonproliferating quiescent and senescent fibroblasts. 
  • Cloning and sequence analysis of the human beta 1-adrenergic receptor 5'-flanking promoter region. 
  • Cloning of DNA corresponding to rare transcripts of rat brain: evidence of transcriptional and post-transcriptional control and of the existence of nonpolyadenylated transcripts. 
  • Cloning of a cDNA encoding bovine erythropoietin and analysis of its transcription in selected tissues. 
  • Cloning of an NF-kappa B subunit which stimulates HIV transcription in synergy with p65. 
  • Cloning of the Arabidopsis clock gene TOC1, an autoregulatory response regulator homolog 
  • Cloning of the promoter region of human endoglin, the target gene for hereditary hemorrhagic telangiectasia type 1. 
  • Cloning, characterization, and genetic mapping of the rat type 2 angiotensin II receptor gene. 
  • Co-orientation of replication and transcription preserves genome integrity. 
  • Co-transcriptional splicing of pre-messenger RNAs: considerations for the mechanism of alternative splicing. 
  • Coactivation of liver receptor homologue-1 by peroxisome proliferator-activated receptor gamma coactivator-1alpha on aromatase promoter II and its inhibition by activated retinoid X receptor suggest a novel target for breast-specific antiestrogen therapy. 
  • Cohesin, CTCF and lymphocyte antigen receptor locus rearrangement. 
  • Colonial differentiation in Streptomyces coelicolor depends on translation of a specific codon within the adpA gene. 
  • Comparative analyses of mechanistic differences among antiestrogens. 
  • Comparative genomics in the Brassicaceae: a family-wide perspective. 
  • Comparative physical and transcript maps of approximately 1 Mb around loop-tail, a gene for severe neural tube defects on distal mouse chromosome 1 and human chromosome 1q22-q23. 
  • Comparison of 5.8S ribosomal DNA sequences among the basidiomycetous yeast genera Cystofilobasidium, Filobasidium and Filobasidiella. 
  • Comparison of direct and indirect methods of carrier detection in an X-linked disease. 
  • Comparison of the expression of three highly related genes, Fgf8, Fgf17 and Fgf18, in the mouse embryo. 
  • Complementary techniques: RNA amplification for gene profiling analysis. 
  • Complete sequence of a gene encoding a human type I keratin: sequences homologous to enhancer elements in the regulatory region of the gene. 
  • Complete sequence of the Drosophila nonmuscle myosin heavy-chain transcript: conserved sequences in the myosin tail and differential splicing in the 5' untranslated sequence. 
  • Complex regulation of human c-kit transcription by promoter repressors, activators, and specific myb elements. 
  • Complex structure and regulation of the ABP/SHBG gene. 
  • Components of a calmodulin-dependent protein kinase cascade. Molecular cloning, functional characterization and cellular localization of Ca2+/calmodulin-dependent protein kinase kinase beta. 
  • Composition and dynamics of the Caenorhabditis elegans early embryonic transcriptome. 
  • Comprehensive analysis of the chromatin landscape in Drosophila melanogaster. 
  • Computational analysis reveals a correlation of exon-skipping events with splicing, transcription and epigenetic factors. 
  • Computational prediction of efficient splice sites for trans-splicing ribozymes. 
  • Connections and regulation of the human estrogen receptor. 
  • Conservation of Endo16 expression in sea urchins despite evolutionary divergence in both cis and trans-acting components of transcriptional regulation. 
  • Constitutive cytokine mRNAs mark natural killer (NK) and NK T cells poised for rapid effector function. 
  • Constitutively active ESR1 mutations in gynecologic malignancies and clinical response to estrogen-receptor directed therapies. 
  • Constructing atomic-resolution RNA structural ensembles using MD and motionally decoupled NMR RDCs. 
  • Control elements within the PWS/AS imprinting box and their function in the imprinting process. 
  • Control of gene expression and assembly of chromosomal subdomains by chromatin regulators with antagonistic functions. 
  • Convergent transcriptional specializations in the brains of humans and song-learning birds. 
  • Cooperation of Sp1 and p300 in the induction of the CDK inhibitor p21WAF1/CIP1 during NGF-mediated neuronal differentiation. 
  • Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3. 
  • Coordination of replication and transcription along a Drosophila chromosome. 
  • Coregulators in nuclear estrogen receptor action: from concept to therapeutic targeting. 
  • Cotranscriptional association of mRNA export factor Yra1 with C-terminal domain of RNA polymerase II. 
  • Cowpox virus contains two copies of an early gene encoding a soluble secreted form of the type II TNF receptor. 
  • Cowpox virus genome encodes a second soluble homologue of cellular TNF receptors, distinct from CrmB, that binds TNF but not LT alpha. 
  • Creation of an active estrogen-responsive element by a single base change in the flanking sequence of a cellular oncogene: a possible mechanism for hormonal carcinogenesis? 
  • Cryptic brain cell injury caused by fetal nicotine exposure is associated with persistent elevations of c-fos protooncogene expression. 
  • Cryptococcus neoformans methionine synthase: expression analysis and requirement for virulence. 
  • Crystal structure of MtaN, a global multidrug transporter gene activator. 
  • Crystal structure of the Bacillus subtilis anti-alpha, global transcriptional regulator, Spx, in complex with the alpha C-terminal domain of RNA polymerase. 
  • Crystal structure of the human LRH-1 DBD-DNA complex reveals Ftz-F1 domain positioning is required for receptor activity. 
  • Current insights on the biology and clinical aspects of VEGF regulation. 
  • Cutting Edge: c-Maf Is Required for Regulatory T Cells To Adopt RORγt+ and Follicular Phenotypes. 
  • Cyclic AMP mediated GSTP1 gene activation in tumor cells involves the interaction of activated CREB-1 with the GSTP1 CRE: a novel mechanism of cellular GSTP1 gene regulation. 
  • Cyclophilin A is localized to the nucleus and controls meiosis in Saccharomyces cerevisiae. 
  • Cytochrome P450IIIA activity and cytokine-mediated synthesis of nitric oxide. 
  • Cytokine induction of nuclear factor kappa B in cycling and growth-arrested cells. Evidence for cell cycle-independent activation. 
  • Cytokine regulation of liver injury and repair. 
  • Cytokine transcriptional events during helper T cell subset differentiation. 
  • Cytological evidence of transcription of highly repeated DNA sequences during the lampbrush stage in Triturus cristatus carnifex. 
  • Cytoskeletal actin gene families of Xenopus borealis and Xenopus laevis. 
  • DNA CpG methylation inhibits binding of NF-kappa B proteins to the HIV-1 long terminal repeat cognate DNA motifs. 
  • DNA Sequence Constraints Define Functionally Active Steroid Nuclear Receptor Binding Sites in Chromatin. 
  • DNA and RNA topoisomerase activities of Top3β are promoted by mediator protein Tudor domain-containing protein 3. 
  • DNA methylation in epigenetic control of gene expression. 
  • DNA replication and transcription programs respond to the same chromatin cues. 
  • De Novo SOX6 Variants Cause a Neurodevelopmental Syndrome Associated with ADHD, Craniosynostosis, and Osteochondromas. 
  • Deciphering the molecular basis of multidrug recognition: crystal structures of the Staphylococcus aureus multidrug binding transcription regulator QacR. 
  • Decoy mRNAs reduce beta-amyloid precursor protein mRNA in neuronal cells. 
  • Decreased circulating macrophage migration inhibitory factor (MIF) protein and blood mononuclear cell MIF transcripts in children with Plasmodium falciparum malaria. 
  • Deep-RACE: Comprehensive Search for Novel ncRNAs Associated to a Specific Locus. 
  • Defining Ca2+/calmodulin-dependent protein kinase cascades in transcriptional regulation. 
  • Defining the human macula transcriptome and candidate retinal disease genes using EyeSAGE. 
  • Definition of the cellular mechanisms which distinguish between hormone and antihormone activated steroid receptors. 
  • Definition of the critical cellular components which distinguish between hormone and antihormone activated progesterone receptor. 
  • Definition of the molecular basis for estrogen receptor-related receptor-alpha-cofactor interactions. 
  • Deletion analysis of bacteriophage T4 tertiary origins. A promoter sequence is required for a rifampicin-resistant replication origin. 
  • Delineation of the intronless nature of the genes for the human and hamster beta 2-adrenergic receptor and their putative promoter regions. 
  • Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2. 
  • Derivatives of plant phenolic compound affect the type III secretion system of Pseudomonas aeruginosa via a GacS-GacA two-component signal transduction system. 
  • Destabilization of simple repetitive DNA sequences by transcription in yeast. 
  • Detailed molecular analysis of 1p36 in neuroblastoma. 
  • Detecting separate time scales in genetic expression data. 
  • Detection of DNA damage in transcriptionally active genes by RT-PCR and assessment of repair of cisplatin-induced damage in the glutathione S-transferase-pi gene in human glioblastoma cells. 
  • Detection of murine cytomegalovirus immediate early 1 transcripts in the spleens of latently infected mice. 
  • Determination of estrogen receptor messenger ribonucleic acid (mRNA) and cytochrome P450 aromatase mRNA levels in adipocytes and adipose stromal cells by competitive polymerase chain reaction amplification. 
  • Developmental and transformation-sensitive expression of the Sparc gene on mouse chromosome 11. 
  • Developmental exposure to organophosphates triggers transcriptional changes in genes associated with Parkinson's disease in vitro and in vivo. 
  • Developmental networks. 
  • Developmental neurotoxicity of organophosphates targets cell cycle and apoptosis, revealed by transcriptional profiles in vivo and in vitro. 
  • Developmental regulation of the gibberellin biosynthetic gene GA1 in Arabidopsis thaliana. 
  • Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins. 
  • Dietary regulation of rat intestinal cholecystokinin gene expression. 
  • Differences in apolipoprotein E3/3 and E4/4 allele-specific gene expression in hippocampus in Alzheimer disease. 
  • Differential Apaf-1 levels allow cytochrome c to induce apoptosis in brain tumors but not in normal neural tissues. 
  • Differential cerebral gene expression during cardiopulmonary bypass in the rat: evidence for apoptosis? 
  • Differential display RT-PCR for identifying novel gene expression in the lung. 
  • Differential effects of toll-like receptor stimulation on mRNA-driven myogenic conversion of human and mouse fibroblasts. 
  • Differential expression and regulation of the glucokinase gene in liver and islets of Langerhans. 
  • Differential expression of VEGF isoforms in mouse during development and in the adult. 
  • Differential expression of immediate early genes in the hippocampus in the kindling model of epilepsy. 
  • Differential expression of the homeobox gene Hox-1.3 in F9 embryonal carcinoma cells. 
  • Differential gene expression from a single transcription unit during spermatogenesis. 
  • Differential induction of mRNAs for the glycolytic and ethanolic fermentative pathways by hypoxia and anoxia in maize seedlings. 
  • Differential osteopontin expression in phenotypically distinct subclones of murine breast cancer cells mediates metastatic behavior. 
  • Differential presentation of protein interaction surfaces on the androgen receptor defines the pharmacological actions of bound ligands. 
  • Differential regulation of estrogen receptor alpha, glucocorticoid receptor and retinoic acid receptor alpha transcriptional activity by melatonin is mediated via different G proteins. 
  • Differential regulation of hepatocyte DNA synthesis by cAMP in vitro in vivo. 
  • Differential regulation of inducible nitric oxide synthase gene expression by ethanol in the human intestinal epithelial cell line DLD-1. 
  • Differential regulation of transcription: repression by unactivated mitogen-activated protein kinase Kss1 requires the Dig1 and Dig2 proteins. 
  • Differentiation of a catecholaminergic CNS cell line modifies tyrosine hydroxylase transcriptional regulation. 
  • Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity. 
  • Dimerization of NF-KB2 with RelA(p65) regulates DNA binding, transcriptional activation, and inhibition by an I kappa B-alpha (MAD-3). 
  • Direct carrier testing in 14 families with haemophilia B. 
  • Direct interactions between corepressors and coactivators permit the integration of nuclear receptor-mediated repression and activation. 
  • Direct regulation of the Na,K pump by signal transduction mechanisms. 
  • Direct sequencing of the activation peptide and the catalytic domain of the factor IX gene in six species. 
  • Direct visualization of cardiac transcription factories reveals regulatory principles of nuclear architecture during pathological remodeling. 
  • Discrimination of vanadium from zinc using gene profiling in human bronchial epithelial cells. 
  • Disparate developmental neurotoxicants converge on the cyclic AMP signaling cascade, revealed by transcriptional profiles in vitro and in vivo. 
  • Disruption of mRNA-RNP formation and sorting to dendritic synapses by antisense oligodeoxynucleotides. 
  • Disruption of the mouse oestrogen receptor gene: resulting phenotypes and experimental findings. 
  • Dissection of the LXXLL nuclear receptor-coactivator interaction motif using combinatorial peptide libraries: discovery of peptide antagonists of estrogen receptors alpha and beta. 
  • Dissection of the molecular circuitry controlling virulence in Francisella tularensis. 
  • Distant conserved sequences flanking endothelial-specific promoters contain tissue-specific DNase-hypersensitive sites and over-represented motifs. 
  • Distinct and histone-specific modifications mediate positive versus negative transcriptional regulation of TSHalpha promoter. 
  • Distinct combinations of NF-kappa B subunits determine the specificity of transcriptional activation. 
  • Distinct regulatory mechanisms governing embryonic versus adult adipocyte maturation. 
  • Distinctive variation in the U3R region of the 5' Long Terminal Repeat from diverse HIV-1 strains. 
  • Distribution of binding sites for thromboxane A2 in the mouse kidney. 
  • Divergent gene regulation and growth effects by NF-kappa B in epithelial and mesenchymal cells of human skin. 
  • Diverse functions within the IAP family. 
  • Diverse molecular mechanisms of transcription regulation by the bacterial alarmone ppGpp. 
  • Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA-binding protein gene. 
  • Down-regulation of neu/HER-2 by interferon-gamma in prostate cancer cells. 
  • Down-regulation of platelet-derived growth factor-D inhibits cell growth and angiogenesis through inactivation of Notch-1 and nuclear factor-kappaB signaling. 
  • Downregulation of RNA polymerase III transcription of the hY3 gene in vitro. 
  • Drosophila RNA polymerase II mutants that affect transcription elongation. 
  • Drosophila TFIID binds to a conserved downstream basal promoter element that is present in many TATA-box-deficient promoters. 
  • Drosophila genome-wide RNAi screens: are they delivering the promise? 
  • Dying for NF-kappaB? Control of cell death by transcriptional regulation of the apoptotic machinery. 
  • Dynamic Metabolite Profiling in an Archaeon Connects Transcriptional Regulation to Metabolic Consequences. 
  • Dynamic interaction between a Drosophila transcription factor and RNA polymerase II. 
  • Dynamic microRNA gene transcription and processing during T cell development. 
  • Dynamic zebrafish interactome reveals transcriptional mechanisms of dioxin toxicity. 
  • Dynamics of BAF-Polycomb complex opposition on heterochromatin in normal and oncogenic states. 
  • Dysfunction of the TP53 tumor suppressor gene in lymphoid malignancies. 
  • Dysregulation of hedgehog signalling predisposes to synovial chondromatosis. 
  • E1A-mediated inhibition of myogenesis correlates with a direct physical interaction of E1A12S and basic helix-loop-helix proteins. 
  • E2A and IRF-4/Pip promote chromatin modification and transcription of the immunoglobulin kappa locus in pre-B cells. 
  • E2F1-Mediated Induction of NFYB Attenuates Apoptosis via Joint Regulation of a Pro-Survival Transcriptional Program. 
  • E2F3 activity is regulated during the cell cycle and is required for the induction of S phase. 
  • E2F4-RB and E2F4-p107 complexes suppress gene expression by transforming growth factor beta through E2F binding sites. 
  • ELF3 is a repressor of androgen receptor action in prostate cancer cells. 
  • ETS transcription factors regulate an enhancer activity in the third intron of TNF-alpha. 
  • EZH2 regulates the transcription of estrogen-responsive genes through association with REA, an estrogen receptor corepressor. 
  • Early de novo DNA methylation and prolonged demethylation in the muscle lineage. 
  • Early fetal hypoxia leads to growth restriction and myocardial thinning. 
  • Ectopic expression of the proto-oncogene Mer in pediatric T-cell acute lymphoblastic leukemia. 
  • Editing the epigenome: technologies for programmable transcription and epigenetic modulation. 
  • Effect of allelic variation at the NACP-Rep1 repeat upstream of the alpha-synuclein gene (SNCA) on transcription in a cell culture luciferase reporter system. 
  • Effect of alpha-isopropylmalate on the synthesis of RNA and protein in Neurospora. 
  • Effect of estrogen on gene expression in the chick oviduct. Regulation of the ovomucoid gene. 
  • Effect of estrogen on the synthesis and processing of ovalbumin messenger RNA in the chick oviduct. 
  • Effects of cholecystokinin on pancreatic ornithine decarboxylase gene expression. 
  • Effects of diethylstilbestrol on rat granulosa cell and thecal/interstitial cell transforming growth factor-beta 2 mRNA expression in vivo: analysis by reverse transcription-polymerase chain reaction. 
  • Effects of early life exposure to ultraviolet C radiation on mitochondrial DNA content, transcription, ATP production, and oxygen consumption in developing Caenorhabditis elegans. 
  • Effects of growth hormone and IGF-I on cardiac hypertrophy and gene expression in mice. 
  • Effects of liver growth factors on hepadnavirus replication in chronically infected duck hepatocytes. 
  • Effects of mismatch repair and Hpr1 on transcription-stimulated mitotic recombination in the yeast Saccharomyces cerevisiae. 
  • Effects of physiological and synthetic IAP antagonism on c-IAP-dependent signaling. 
  • Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release. 
  • Efficacy of gene therapy for a prototypical lysosomal storage disease (GSD-II) is critically dependent on vector dose, transgene promoter, and the tissues targeted for vector transduction. 
  • Elevated expression of a subset of interferon inducible genes in primary bone marrow cells expressing p185 Bcr-Abl versus p210 Bcr-Abl by DNA microarray analysis. 
  • Elevated nitric oxide production in children with malarial anemia: hemozoin-induced nitric oxide synthase type 2 transcripts and nitric oxide in blood mononuclear cells. 
  • Elongation by Drosophila RNA polymerase II. Transcription of 3'-extended DNA templates. 
  • Endogenous S-nitrosothiols protect against myocardial injury. 
  • Endosymbiont gene functions impaired and rescued by polymerase infidelity at poly(A) tracts. 
  • Endotoxin and NO induce MIP-1gamma gene transcription in ANA-1 murine macrophages. 
  • Endotoxin stress-response in cardiomyocytes: NF-kappaB activation and tumor necrosis factor-alpha expression. 
  • Endotoxin-mediated nitric oxide synthesis inhibits IL-1beta gene transcription in ANA-1 murine macrophages. 
  • Endotoxin-mediated synthesis of nitric oxide is dependent on Gq protein signal transduction. 
  • Enforced expression of wild-type p53 curtails the transcription of the O(6)-methylguanine-DNA methyltransferase gene in human tumor cells and enhances their sensitivity to alkylating agents. 
  • Enhanced central response to dehydration in mice lacking angiotensin AT(1a) receptors. 
  • Enhancement of estrogen receptor transcriptional activity by the coactivator GRIP-1 highlights the role of activation function 2 in determining estrogen receptor pharmacology. 
  • Enhancer Histone Acetylation Modulates Transcriptional Bursting Dynamics of Neuronal Activity-Inducible Genes. 
  • Epidermal growth factor receptor signaling promotes metastatic prostate cancer through microRNA-96-mediated downregulation of the tumor suppressor ETV6. 
  • Epidermal growth factor receptor-related protein inhibits cell growth and invasion in pancreatic cancer. 
  • Epigenetic Silencing of Recombinant Adeno-associated Virus Genomes by NP220 and the HUSH Complex. 
  • Epigenetic activation of unintegrated HIV-1 genomes by gut-associated short chain fatty acids and its implications for HIV infection. 
  • Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition. 
  • Epigenetics and psychostimulant addiction. 
  • Equalizing cDNA subtraction based on selective suppression of polymerase chain reaction: cloning of Jurkat cell transcripts induced by phytohemaglutinin and phorbol 12-myristate 13-acetate. 
  • Eradication of solid human breast tumors in nude mice with an intravenously injected light-emitting oncolytic vaccinia virus. 
  • Erbin is a protein concentrated at postsynaptic membranes that interacts with PSD-95. 
  • Escherichia coli mutants thermosensitive for deoxyribonucleic acid gyrase subunit A: effects on deoxyribonucleic acid replication, transcription, and bacteriophage growth. 
  • Essential role for Smad3 in regulating MCP-1 expression and vascular inflammation. 
  • Estrogen and thyroid hormone interaction on regulation of gene expression. 
  • Estrogen excess associated with novel gain-of-function mutations affecting the aromatase gene. 
  • Estrogen induction of ovalbumin mRNA: evidence for transcription control. 
  • Estrogen-induced mitogenesis of MCF-7 cells does not require the induction of mitogen-activated protein kinase activity. 
  • Ethanol inhibits liver regeneration in rats without reducing transcripts of key protooncogenes. 
  • Ethanol interferes with regeneration-associated changes in biotransforming enzymes: a potential mechanism underlying ethanol's carcinogenicity? 
  • Eukaryotic gene transcription with purified components. 
  • Eukaryotic transcription termination factor La mediates transcript release and facilitates reinitiation by RNA polymerase III. 
  • Evaluation of CD86/CD28 and CD40/CD154 pathways in regulating monocyte-derived CD80 expression during their interaction with allogeneic endothelium. 
  • Evaluation of chemicals with endocrine modulating activity in a yeast-based steroid hormone receptor gene transcription assay. 
  • Evidence from molecular cloning that SPARC, a major product of mouse embryo parietal endoderm, is related to an endothelial cell 'culture shock' glycoprotein of Mr 43,000. 
  • Evidence that a free-running oscillator drives G1 events in the budding yeast cell cycle. 
  • Exemestane's 17-hydroxylated metabolite exerts biological effects as an androgen. 
  • Exercise stimulates Pgc-1alpha transcription in skeletal muscle through activation of the p38 MAPK pathway. 
  • Exon 10b of the NF1 gene represents a mutational hotspot and harbors a recurrent missense mutation Y489C associated with aberrant splicing. 
  • Expansion of Signal Transduction Pathways in Fungi by Extensive Genome Duplication. 
  • Expansion of adult beta-cell mass in response to increased metabolic demand is dependent on HNF-4alpha. 
  • Expression and function of the uvsW gene of bacteriophage T4. 
  • Expression of Kingella kingae type IV pili is regulated by sigma54, PilS, and PilR. 
  • Expression of TGF-beta-related genes during mouse embryo whisker morphogenesis. 
  • Expression of a constitutive form of calcium/calmodulin dependent protein kinase II leads to arrest of the cell cycle in G2. 
  • Expression of a distinctive BCR-ABL oncogene in Ph1-positive acute lymphocytic leukemia (ALL). 
  • Expression of a peptide inhibitor of protein phosphatase 1 increases phosphorylation and activity of CREB in NIH 3T3 fibroblasts. 
  • Expression of chimeric tRNA-driven antisense transcripts renders NIH 3T3 cells highly resistant to Moloney murine leukemia virus replication. 
  • Expression of cyp26b1 during zebrafish early development. 
  • Expression of erythropoietin receptor splice variants in human cancer. 
  • Expression of five selected human mismatch repair genes simultaneously detected in normal and cancer cell lines by a nonradioactive multiplex reverse transcription-polymerase chain reaction. 
  • Expression of functional chicken oviduct progesterone receptors in yeast (Saccharomyces cerevisiae). 
  • Expression of osteocalcin and its transcriptional regulators core-binding factor alpha 1 and MSX2 in osteoid-forming tumours. 
  • Expression of photosynthesis genes in relation to nitrogen fixation in the diazotrophic filamentous nonheterocystous cyanobacterium Trichodesmium sp. IMS 101. 
  • Expression of rRNA and tRNA genes in Escherichia coli: evidence for feedback regulation by products of rRNA operons. 
  • Expression of renin-angiotensin system and extracellular matrix genes in cardiovascular cells and its regulation through AT1 receptor. 
  • Expression of surface CD1d in the extravillous trophoblast cells of early gestational placenta is downregulated in a manner dependent on trophoblast differentiation. 
  • Expression of transcription factor E2F1 induces quiescent cells to enter S phase. 
  • Expression of transforming growth factor-beta type II receptor in rat lung is regulated during development. 
  • Expression profiling of in vivo ductal carcinoma in situ progression models identified B cell lymphoma-9 as a molecular driver of breast cancer invasion. 
  • Expression profiling using microarrays fabricated by an ink-jet oligonucleotide synthesizer. 
  • Extensive evolutionary changes in regulatory element activity during human origins are associated with altered gene expression and positive selection. 
  • Extracellular superoxide dismutase. 
  • Extreme thyroid hormone resistance in a patient with a novel truncated TR mutant. 
  • F-actin homeostasis through transcriptional regulation and proteasome-mediated proteolysis. 
  • FBW2 targets GCMa to the ubiquitin-proteasome degradation system. 
  • FGF23 at the crossroads of phosphate, iron economy and erythropoiesis. 
  • FHIT and FRA3B 3p14.2 allele loss are common in lung cancer and preneoplastic bronchial lesions and are associated with cancer-related FHIT cDNA splicing aberrations. 
  • FKF1 F-box protein mediates cyclic degradation of a repressor of CONSTANS in Arabidopsis 
  • Failure of terminal erythroid differentiation in EKLF-deficient mice is associated with cell cycle perturbation and reduced expression of E2F2. 
  • Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) alpha knock-out mice. Evidence for compensatory regulation by PPAR delta. 
  • Female steroid hormones and target cell nuclei. 
  • Fluid shear stress induces endothelial transforming growth factor beta-1 transcription and production. Modulation by potassium channel blockade. 
  • Follicle-stimulating hormone, the Sertoli cell, and spermatogenesis. 
  • Formation of a rate-limiting intermediate in 5S RNA gene transcription. 
  • Formation of supercoiling domains in plasmid pBR322. 
  • FoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs -8118 and -7750 upstream from the transcription start site. 
  • FoxO1 deacetylation regulates thyroid hormone-induced transcription of key hepatic gluconeogenic genes. 
  • Fractionation of transcription factors for RNA polymerase II from Drosophila Kc cell nuclear extracts. 
  • Fragile X males with unmethylated, full mutation trinucleotide repeat expansions have elevated levels of FMR1 messenger RNA. 
  • Frequent overexpression of ETS-related gene-1 (ERG1) in prostate cancer transcriptome. 
  • From induction to conduction: how intrinsic transcriptional priming of extrinsic neuronal connectivity shapes neuronal identity. 
  • Functional analysis of the transforming growth factor beta responsive elements in the WAF1/Cip1/p21 promoter. 
  • Functional coordination and HuR-mediated regulation of mRNA stability during T cell activation. 
  • Functional divergence in tandemly duplicated Arabidopsis thaliana trypsin inhibitor genes. 
  • Functional domains of the human vitamin D3 receptor regulate osteocalcin gene expression. 
  • Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans. 
  • Functional heterogeneity of mammalian TATA-box sequences revealed by interaction with a cell-specific enhancer. 
  • Functionally significant renal allograft rejection is defined by transcriptional criteria. 
  • Functions that protect Escherichia coli from DNA-protein crosslinks. 
  • Further evidence that transposition of Tn5 in Escherichia coli is strongly enhanced by constitutively activated RecA proteins. 
  • Fusion order controls expression level and activity of elastin-like polypeptide fusion proteins. 
  • G Protein-Coupled Receptor Endocytosis Confers Uniformity in Responses to Chemically Distinct Ligands. 
  • G9a Promotes Breast Cancer Recurrence through Repression of a Pro-inflammatory Program. 
  • GTL1 and DF1 regulate root hair growth through transcriptional repression of ROOT HAIR DEFECTIVE 6-LIKE 4 in Arabidopsis. 
  • Gamma-globin gene promoter elements required for interaction with globin enhancers. 
  • Gender differences in molecular remodeling in pressure overload hypertrophy. 
  • Gene and protein expressions of nitric oxide synthases in ischemia-reperfused peripheral nerve of the rat. 
  • Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300. 
  • Gene expression analysis of messenger RNP complexes. 
  • Gene expression disruptions of organism versus organ in Drosophila species hybrids. 
  • Gene expression of the renin-angiotensin system in human tissues. Quantitative analysis by the polymerase chain reaction. 
  • Gene expression profiling in RAS oncogene-transformed cell lines and in solid tumors using subtractive suppression hybridization and cDNA arrays. 
  • Gene expression signatures as a guide to treatment strategies for in-transit metastatic melanoma. 
  • Gene transcription, metabolite and lipid profiling in eco-indicator daphnia magna indicate diverse mechanisms of toxicity by legacy and emerging flame-retardants. 
  • Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells. 
  • Genetic analysis of transcription-associated mutation in Saccharomyces cerevisiae. 
  • Genetic evidence for preferential strand transfer during meiotic recombination in yeast. 
  • Genetic mechanisms that determine oxidative capacity of striated muscles. Control of gene transcription. 
  • Genetic requirements for spontaneous and transcription-stimulated mitotic recombination in Saccharomyces cerevisiae. 
  • Genetic studies in Alzheimer's disease with an NACP/alpha-synuclein polymorphism. 
  • Genistein and bisphenol A exposure cause estrogen receptor 1 to bind thousands of sites in a cell type-specific manner. 
  • Genome accessibility is widely preserved and locally modulated during mitosis. 
  • Genome wide analysis and clinical correlation of chromosomal and transcriptional mutations in cancers of the biliary tract. 
  • Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types. 
  • Genome-wide identification of calcium-response factor (CaRF) binding sites predicts a role in regulation of neuronal signaling pathways. 
  • Genome-wide regulatory analysis using en masse nuclear run-ons and ribonomic profiling with autoimmune sera. 
  • Genome-wide survey and expression analysis of the OSCA gene family in rice. 
  • Genomic FHIT analysis in RER+ and RER- adenocarcinomas of the pancreas. 
  • Genomic amplification with transcript sequencing. 
  • Genomic distribution of CHD7 on chromatin tracks H3K4 methylation patterns. 
  • Genomic organization and polymorphism of human angiotensin II type 2 receptor: no evidence for its gene mutation in two families of human premature ovarian failure syndrome. 
  • Genomic organization of the human T-cell antigen-receptor alpha/delta locus. 
  • Genomic sequence and expression of a cloned human carbonyl reductase gene with daunorubicin reductase activity. 
  • Genomic structure and amino acid sequence domains of the human La autoantigen. 
  • Germline and somatic thyroid hormone receptor mutations in man. 
  • Germline transcription: a key regulator of accessibility and recombination. 
  • Gill-specific transcriptional regulation of Na+/K+ -ATPase alpha-subunit in the euryhaline shore crab Pachygrapsus marmoratus: sequence variants and promoter structure. 
  • Gli2 and p53 cooperate to regulate IGFBP-3- mediated chondrocyte apoptosis in the progression from benign to malignant cartilage tumors. 
  • Global Transcriptional Programs in Archaea Share Features with the Eukaryotic Environmental Stress Response. 
  • Global control of cell-cycle transcription by coupled CDK and network oscillators. 
  • Global re-wiring of p53 transcription regulation by the hepatitis B virus X protein. 
  • Global transcriptional and proteomic analysis of the Sig1 heat shock regulon of Deinococcus radiodurans. 
  • Global transcriptome profile of Cryptococcus neoformans during exposure to hydrogen peroxide induced oxidative stress. 
  • Global translational reprogramming is a fundamental layer of immune regulation in plants. 
  • GlpR Is a Direct Transcriptional Repressor of Fructose Metabolic Genes in Haloferax volcanii. 
  • Glucocorticoid regulation of preproglucagon transcription and RNA stability during stress. 
  • Glucose metabolism attenuates p53 and Puma-dependent cell death upon growth factor deprivation. 
  • Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression. 
  • Glutamate receptor activation regulates mRNA at both transcriptional and posttranscriptional levels. 
  • Glycoprotein nonmetastatic melanoma protein B, a potential molecular therapeutic target in patients with glioblastoma multiforme. 
  • Gnotobiotic zebrafish reveal evolutionarily conserved responses to the gut microbiota. 
  • Gonadotropin regulation of the rat proopiomelanocortin promoter: characterization by transfection of primary ovarian granulosa cells. 
  • Gradients of transgene expression directed by the human myoglobin promoter in the developing mouse heart. 
  • Granulocyte-macrophage colony-stimulating factor and interleukin-3 mRNAs are produced by a small fraction of blood mononuclear cells. 
  • Group-I intron family in the nuclear ribosomal RNA small subunit genes of Cenococcum geophilum isolates. 
  • Guanine repeat-containing sequences confer transcription-dependent instability in an orientation-specific manner in yeast. 
  • HDAC4 regulates muscle fiber type-specific gene expression programs. 
  • HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor. 
  • HEC of a job regulating stem cells. 
  • HES factors regulate specific aspects of chondrogenesis and chondrocyte hypertrophy during cartilage development. 
  • HIF-1alpha induces genetic instability by transcriptionally downregulating MutSalpha expression. 
  • HIV-1 Proviral Transcription and Latency in the New Era. 
  • HLA-B-associated transcript 3 (Bat3)/Scythe is essential for p300-mediated acetylation of p53. 
  • HNF-4alpha: from MODY to late-onset type 2 diabetes. 
  • HNF4α regulates sulfur amino acid metabolism and confers sensitivity to methionine restriction in liver cancer. 
  • Half-site arrangement of hybrid glucocorticoid and thyroid hormone response elements specifies thyroid hormone receptor complex binding to DNA and transcriptional activity. 
  • Heat shock-induced appearance of RNA polymerase II in karyoskeletal protein-enriched (nuclear "matrix") fractions correlates with transcriptional shutdown in Drosophila melanogaster. 
  • Heat-shock-specific phosphorylation and transcriptional activity of RNA polymerase II. 
  • Hel-N1: an autoimmune RNA-binding protein with specificity for 3' uridylate-rich untranslated regions of growth factor mRNAs. 
  • Hemorrhage in lesions caused by cowpox virus is induced by a viral protein that is related to plasma protein inhibitors of serine proteases. 
  • Hepatic SRC-1 activity orchestrates transcriptional circuitries of amino acid pathways with potential relevance for human metabolic pathogenesis. 
  • Hepatocellular expression of glucose-6-phosphatase is unaltered during hepatic regeneration. 
  • Hepatocyte nuclear factor-4alpha mediates redox sensitivity of inducible nitric-oxide synthase gene transcription. 
  • Herpes Simplex Virus 1 Infection of Tree Shrews Differs from That of Mice in the Severity of Acute Infection and Viral Transcription in the Peripheral Nervous System. 
  • Hierarchical assembly and disassembly of a transcriptionally active RAG locus in CD4+CD8+ thymocytes. 
  • High frequency of hypermethylation at the 14-3-3 sigma locus leads to gene silencing in breast cancer. 
  • High level expression of biologically active estrogen receptor in Saccharomyces cerevisiae. 
  • High-resolution genome-wide in vivo footprinting of diverse transcription factors in human cells. 
  • High-resolution labeling and functional manipulation of specific neuron types in mouse brain by Cre-activated viral gene expression. 
  • High-throughput RNA isolation technologies. New tools for high-resolution gene expression profiling in plant systems. 
  • HipBA-promoter structures reveal the basis of heritable multidrug tolerance. 
  • Hormonal and metabolic regulation of human chondrosarcoma in vitro. 
  • Hormone control and expression of androgen receptor coregulator MAGE-11 in human endometrium during the window of receptivity to embryo implantation. 
  • Host cell transcriptome profile during wild-type and attenuated dengue virus infection. 
  • Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections. 
  • HspR is a global negative regulator of heat shock gene expression in Deinococcus radiodurans. 
  • Human La antigen is required for the hepatitis C virus internal ribosome entry site-mediated translation. 
  • Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets. 
  • Human apolipoprotein E2, E3, and E4 isoform-specific transgenic mice: human-like pattern of glial and neuronal immunoreactivity in central nervous system not observed in wild-type mice. 
  • Human brain glycogen phosphorylase. Cloning, sequence analysis, chromosomal mapping, tissue expression, and comparison with the human liver and muscle isozymes. 
  • Human centromeric chromatin is a dynamic chromosomal domain that can spread over noncentromeric DNA. 
  • Human estrogen receptor transactivational capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions. 
  • Human glycogen debranching enzyme gene (AGL): complete structural organization and characterization of the 5' flanking region. 
  • Human peripheral mononuclear cells do not show proinflammatory patterns of cytokine transcription in early trauma: a preliminary report. 
  • Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function. 
  • Human promoters are intrinsically directional. 
  • Human smooth muscle alpha-actin gene is a transcriptional target of the p53 tumor suppressor protein. 
  • Hydrophobic residues Phe751 and Leu753 are essential for STAT5 transcriptional activity. 
  • Hyperosmotic stress stimulates promoter activity and regulates cellular utilization of the serum- and glucocorticoid-inducible protein kinase (Sgk) by a p38 MAPK-dependent pathway. 
  • Hyperphosphorylated C-terminal repeat domain-associating proteins in the nuclear proteome link transcription to DNA/chromatin modification and RNA processing. 
  • Hypoxia Signaling Cascade for Erythropoietin Production in Hepatocytes. 
  • Hypoxia in the thymus: role of oxygen tension in thymocyte survival. 
  • IFN-{beta} signaling positively regulates tumorigenesis in aggressive fibromatosis, potentially by modulating mesenchymal progenitors. 
  • IFN-α inhibits telomerase in human CD8⁺ T cells by both hTERT downregulation and induction of p38 MAPK signaling. 
  • Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. 
  • Identification and characterization of cDNA clones specific for cholesterol side-chain cleavage cytochrome P-450. 
  • Identification and functional characterization of the human glutathione S-transferase P1 gene as a novel transcriptional target of the p53 tumor suppressor gene. 
  • Identification and sequence of the initiation site for rat 45S ribosomal RNA synthesis. 
  • Identification of E2A target genes in B lymphocyte development by using a gene tagging-based chromatin immunoprecipitation system. 
  • Identification of Smoking-Associated Differentially Methylated Regions Using Reduced Representation Bisulfite Sequencing and Cell type-Specific Enhancer Activation and Gene Expression. 
  • Identification of a Novel Coregulator, SH3YL1, That Interacts With the Androgen Receptor N-Terminus. 
  • Identification of a distinctive mutation spectrum associated with high levels of transcription in yeast. 
  • Identification of a genetic signature of activated signal transducer and activator of transcription 3 in human tumors. 
  • Identification of a muscle-specific enhancer within the 5'-flanking region of the human myoglobin gene. 
  • Identification of a negative regulatory element involved in tissue-specific expression of mouse renin genes. 
  • Identification of a negative regulatory function for steroid receptors. 
  • Identification of a negative regulatory surface within estrogen receptor alpha provides evidence in support of a role for corepressors in regulating cellular responses to agonists and antagonists. 
  • Identification of a new subclass of Alu DNA repeats which can function as estrogen receptor-dependent transcriptional enhancers. 
  • Identification of a novel set of genes regulated by a unique liver X receptor-alpha -mediated transcription mechanism. 
  • Identification of a structural gene for a RNA polymerase II polypeptide in Drosophila melanogaster and mammalian species. 
  • Identification of a third autonomous activation domain within the human estrogen receptor. 
  • Identification of a two-component fatty acid kinase responsible for host fatty acid incorporation by Staphylococcus aureus. 
  • Identification of an essential site for transcriptional activation within the human T-cell receptor delta enhancer. 
  • Identification of calcium-modulating cyclophilin ligand (CAML) as transducer of angiotensin II-mediated nuclear factor of activated T cells (NFAT) activation. 
  • Identification of co-regulated transcripts affecting male body size in Drosophila. 
  • Identification of functional elements and regulatory circuits by Drosophila modENCODE. 
  • Identification of mZnf8, a mouse Krüppel-like transcriptional repressor, as a novel nuclear interaction partner of Smad1. 
  • Identification of negative and positive regulatory elements in the human renin gene. 
  • Identification of novel innate immune genes by transcriptional profiling of macrophages stimulated with TLR ligands. 
  • Identification of novel steroid-response elements. 
  • Identification of specific protein-RNA target sites using libraries of natural sequences. 
  • Identification of the gene for fly non-muscle myosin heavy chain: Drosophila myosin heavy chains are encoded by a gene family. 
  • Identification of the promoter region of the human betaIGH3 gene. 
  • Identification of the sequences within the human complement 3 promoter required for estrogen responsiveness provides insight into the mechanism of tamoxifen mixed agonist activity. 
  • Identification, molecular cloning, and mutagenesis of Saccharomyces cerevisiae RNA polymerase genes. 
  • Imidazole acetic acid as a substitute for cAMP. 
  • Immune surveillance by mast cells during dengue infection promotes natural killer (NK) and NKT-cell recruitment and viral clearance. 
  • Immunomodulation of human CD8⁺ T cells by thymoglobulin in vitro. 
  • Importance of the tmRNA system for cell survival when transcription is blocked by DNA-protein cross-links. 
  • Improved gene expression upon transfer of the adenosine deaminase minigene outside the transcriptional unit of a retroviral vector. 
  • In Situ Gene Therapy via AAV-CRISPR-Cas9-Mediated Targeted Gene Regulation. 
  • In Vitro Transcribed mRNA Vaccines with Programmable Stimulation of Innate Immunity. 
  • In cardiomyocyte hypoxia, insulin-like growth factor-I-induced antiapoptotic signaling requires phosphatidylinositol-3-OH-kinase-dependent and mitogen-activated protein kinase-dependent activation of the transcription factor cAMP response element-binding protein. 
  • In mice with type 2 diabetes, a vascular endothelial growth factor (VEGF)-activating transcription factor modulates VEGF signaling and induces therapeutic angiogenesis after hindlimb ischemia. 
  • In vitro analysis of the human antiporcine T-cell repertoire. 
  • In vitro selection of an RNA epitope immunologically cross-reactive with a peptide. 
  • In vitro selection of aptamers from RNA libraries. 
  • In vitro transcriptional studies of the roles of the thyroid hormone (T3) response elements and minimal promoters in T3-stimulated gene transcription. 
  • In vivo differences between endothelial transcriptional profiles of coronary and iliac arteries revealed by microarray analysis 
  • In vivo growth conditions suppress the expression of ganglioside GM2 and favour that of lacto series gangliosides in the human glioma D-54MG cell line. 
  • IncFII plasmid incompatibility product and its target are both RNA transcripts. 
  • Incompatibility and IncFII plasmid replication control. 
  • Incorporation of ribonucleoside 5'-(alpha-P-borano)triphosphates into a 20-mer RNA by T7 RNA polymerase. 
  • Independent signals control expression of the calcineurin inhibitory proteins MCIP1 and MCIP2 in striated muscles. 
  • Indistinguishable nuclear factor binding to functional core sites of the T-cell receptor delta and murine leukemia virus enhancers. 
  • Induction by leptin of uncoupling protein-2 and enzymes of fatty acid oxidation. 
  • Induction of CD4(+) and CD8(+) T-cell responses to the human stromal antigen, fibroblast activation protein: implication for cancer immunotherapy. 
  • Induction of SENP1 in myocardium contributes to abnormities of mitochondria and cardiomyopathy. 
  • Induction of T cell CD7 gene transcription by nonmitogenic ionomycin-induced transmembrane calcium flux. 
  • Induction of ferritin and heme oxygenase-1 by endotoxin in the lung. 
  • Induction of interleukin-6 mRNA in rat alveolar macrophages by in vitro exposure to both Cryptococcus neoformans and anti-C. neoformans antiserum. 
  • Induction of lef1 during zebrafish fin regeneration. 
  • Induction of polyclonal prostate cancer-specific CTL using dendritic cells transfected with amplified tumor RNA. 
  • Induction of the unfolded protein response drives enhanced metabolism and chemoresistance in glioma cells. 
  • Inefficient reprogramming of fibroblasts into cardiomyocytes using Gata4, Mef2c, and Tbx5. 
  • Inflammation and functional iron deficiency regulate fibroblast growth factor 23 production. 
  • Information processing without brains--the power of intercellular regulators in plants. 
  • Informative structure priors: joint learning of dynamic regulatory networks from multiple types of data. 
  • Inhibition of 1,25-dihydroxyvitamin D3-dependent transcription by synthetic LXXLL peptide antagonists that target the activation domains of the vitamin D and retinoid X receptors. 
  • Inhibition of CYP1A1 enzyme activity in mouse hepatoma cell culture by soybean isoflavones. 
  • Inhibition of HIV-1 proviral DNA synthesis and RNA accumulation by mismatched dsRNA. 
  • Inhibition of NF-kappa B by S-nitrosylation. 
  • Inhibition of androgen receptor-dependent transcriptional activity by DDT isomers and methoxychlor in HepG2 human hepatoma cells. 
  • Inhibition of prostate cancer cell growth by second-site androgen receptor antagonists. 
  • Inhibition of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase pathway induces p53-independent transcriptional regulation of p21(WAF1/CIP1) in human prostate carcinoma cells. 
  • Inhibitory effects of vesicular stomatitis virus on cellular and influenza viral RNA metabolism and protein synthesis. 
  • Inositol phosphate multikinase dependent transcriptional control. 
  • Insights into X-linked retinitis pigmentosa type 3, allied diseases and underlying pathomechanisms. 
  • Insulin-like growth factor I induces tumor hexokinase RNA expression in cancer cells. 
  • Integrated detection of natural antisense transcripts using strand-specific RNA sequencing data. 
  • Integrated proteomic and transcriptomic profiling of mouse lung development and Nmyc target genes. 
  • Integrative analysis identifies targetable CREB1/FoxA1 transcriptional co-regulation as a predictor of prostate cancer recurrence. 
  • Interaction between transcriptional activator protein LAC9 and negative regulatory protein GAL80. 
  • Interaction of Galpha 12 and Galpha 13 with the cytoplasmic domain of cadherin provides a mechanism for beta -catenin release. 
  • Interaction of atrial natriuretic polypeptide and angiotensin II on protooncogene expression and vascular cell growth. 
  • Interaction of the Dr1 inhibitory factor with the TATA binding protein is disrupted by adenovirus E1A. 
  • Interactions between p53 and MDM2 in a mammalian cell cycle checkpoint pathway. 
  • Interactions between sustained contractile activity and beta-adrenergic receptors in regulation of gene expression in skeletal muscles. 
  • Interactions of estrogen- and thyroid hormone receptors on a progesterone receptor estrogen response element (ERE) sequence: a comparison with the vitellogenin A2 consensus ERE. 
  • Interferon regulatory factors are transcriptional regulators of adipogenesis. 
  • Intestinal apolipoprotein AI gene transcription is regulated by multiple distinct DNA elements and is synergistically activated by the orphan nuclear receptor, hepatocyte nuclear factor 4. 
  • Intracellular CMTM2 negatively regulates human immunodeficiency virus type-1 transcription through targeting the transcription factors AP-1 and CREB. 
  • Intracellular lipid metabolism impairs β cell compensation during diet-induced obesity. 
  • Intragenic regulation of the synthesis of phi chi 174 gene A proteins. 
  • Intronic cis-regulatory modules mediate tissue-specific and microbial control of angptl4/fiaf transcription. 
  • InvB is a type III secretion chaperone specific for SspA. 
  • Investigating Conservation of the Cell-Cycle-Regulated Transcriptional Program in the Fungal Pathogen, Cryptococcus neoformans. 
  • Involvement of Sonic hedgehog (Shh) in mouse embryonic lung growth and morphogenesis. 
  • Ionotropic glutamate receptor subtypes activate c-fos transcription by distinct calcium-requiring intracellular signaling pathways. 
  • Iron increases expression of iron-export protein MTP1 in lung cells. 
  • Isolation and characterization of a new chemokine receptor gene, the putative chicken CXCR1. 
  • Isolation and characterization of cDNAs encoding human brain ankyrins reveal a family of alternatively spliced genes. 
  • Isolation and characterization of the rat chromosomal gene for a polypeptide (pS1) antigenically related to statin. 
  • Isolation and functional analysis of the mouse RXRgamma1 gene promoter in anterior pituitary cells. 
  • Isolation and initial characterization of the 5' flanking region of the human and murine cyclic guanosine monophosphate-phosphodiesterase beta-subunit genes. 
  • Isolation and initial characterization of the BRCA2 promoter. 
  • Isolation of a diverged homeobox gene, MOX1, from the BRCA1 region on 17q21 by solution hybrid capture. 
  • Isolation of the structural gene for calmodulin. 
  • JMJD5 couples with CDK9 to release the paused RNA polymerase II. 
  • Juglone, an inhibitor of the peptidyl-prolyl isomerase Pin1, also directly blocks transcription. 
  • KRAS Activation and over-expression of SIRT1/BCL6 Contributes to the Pathogenesis of Endometriosis and Progesterone Resistance. 
  • Kin28, the TFIIH-associated carboxy-terminal domain kinase, facilitates the recruitment of mRNA processing machinery to RNA polymerase II. 
  • Kinome screen of ferroptosis reveals a novel role of ATM in regulating iron metabolism. 
  • LXRalpha functions as a cAMP-responsive transcriptional regulator of gene expression. 
  • Lack of genomic imprinting of DNA primase, polypeptide 2 (PRIM2) in human term placenta and white blood cells. 
  • Lack of requirement of osteopontin for inflammation, bone erosion, and cartilage damage in the K/BxN model of autoantibody-mediated arthritis. 
  • Lactic acidosis triggers starvation response with paradoxical induction of TXNIP through MondoA. 
  • Large-scale mapping and validation of Escherichia coli transcriptional regulation from a compendium of expression profiles. 
  • Learning new tricks from old dogs: beta-adrenergic receptors teach new lessons on firing up adipose tissue metabolism. 
  • Learning protein-DNA interaction landscapes by integrating experimental data through computational models. 
  • Lefty inhibits receptor-regulated Smad phosphorylation induced by the activated transforming growth factor-beta receptor. 
  • Ligand-selective interactions of ER detected in living cells by fluorescence resonance energy transfer. 
  • Ligand-specific dynamics of the androgen receptor at its response element in living cells. 
  • Ligation of cell surface GRP78 with antibody directed against the COOH-terminal domain of GRP78 suppresses Ras/MAPK and PI 3-kinase/AKT signaling while promoting caspase activation in human prostate cancer cells. 
  • Light-inducible gene regulation with engineered zinc finger proteins. 
  • Liver X receptor is a regulator of orphan nuclear receptor NOR-1 gene transcription in adipocytes. 
  • Liver genomic responses to ciguatoxin: evidence for activation of phase I and phase II detoxification pathways following an acute hypothermic response in mice. 
  • LncRNA wires up Hippo and Hedgehog signaling to reprogramme glucose metabolism. 
  • Localization of a retroviral element within the rd gene coding for the beta subunit of cGMP phosphodiesterase. 
  • Localized H3K36 methylation states define histone H4K16 acetylation during transcriptional elongation in Drosophila. 
  • Localizing synaptic mRNAs at the neuromuscular junction: it takes more than transcription. 
  • Locus-specific variation in phosphorylation state of RNA polymerase II in vivo: correlations with gene activity and transcript processing. 
  • Loss of phosphatase and tensin homologue increases transforming growth factor beta-mediated invasion with enhanced SMAD3 transcriptional activity. 
  • Loss of the sigma activity of RNA polymerase of Bacillus subtilis during sporulation. 
  • Loss of tumor suppressor KDM6A amplifies PRC2-regulated transcriptional repression in bladder cancer and can be targeted through inhibition of EZH2. 
  • Low K+ promotes NF-kappaB/DNA binding in neuronal apoptosis induced by K+ loss. 
  • Lysosomal inhibition attenuates peroxisomal gene transcription via suppression of PPARA and PPARGC1A levels. 
  • MCF-7 and T47D human breast cancer cells contain a functional peroxisomal response. 
  • MGSA/GRO transcription is differentially regulated in normal retinal pigment epithelial and melanoma cells. 
  • MIG-10 (Lamellipodin) stabilizes invading cell adhesion to basement membrane and is a negative transcriptional target of EGL-43 in C. elegans. 
  • MOP2 (SLA2) affects the abundance of the plasma membrane H(+)-ATPase of Saccharomyces cerevisiae. 
  • Maf1 is an essential mediator of diverse signals that repress RNA polymerase III transcription. 
  • Maleylated-BSA induces hydrolysis of PIP2, fluxes of Ca2+, NF-kappaB binding, and transcription of the TNF-alpha gene in murine macrophages. 
  • Mammalian Y chromosomes retain widely expressed dosage-sensitive regulators. 
  • Mammalian homologs of Drosophila ELAV localized to a neuronal subset can bind in vitro to the 3' UTR of mRNA encoding the Id transcriptional repressor. 
  • Mapping and characterization of the functional domains responsible for the differential activity of the A and B isoforms of the human progesterone receptor. 
  • Mapping mutations in genes encoding the two large subunits of Drosophila RNA polymerase II defines domains essential for basic transcription functions and for proper expression of developmental genes. 
  • Mapping of the human renin transcription start site: evidence for a single functional promoter. 
  • Mapping the complexity of transcription control in higher eukaryotes. 
  • Mast cell interleukin-10 drives localized tolerance in chronic bladder infection. 
  • Mating type (MAT) locus and possible sexuality of the opportunistic pathogen Exophiala dermatitidis. 
  • Matrix gla protein is regulated by a mechanism functionally related to the calcium-sensing receptor. 
  • Mechanism of insulin gene regulation by the pancreatic transcription factor Pdx-1: application of pre-mRNA analysis and chromatin immunoprecipitation to assess formation of functional transcriptional complexes. 
  • Mechanisms controlling agonist and antagonist potential of selective progesterone receptor modulators (SPRMs). 
  • Mechanisms of chromium-induced suppression of RNA synthesis in cellular and cell-free systems: relationship to RNA polymerase arrest. 
  • Mechanisms of specificity in neuronal activity-regulated gene transcription. 
  • Membrane association of the myristoylated alanine-rich C kinase substrate (MARCKS) protein appears to involve myristate-dependent binding in the absence of a myristoyl protein receptor. 
  • Memory of Inflammation in Regulatory T Cells. 
  • Messenger RNAs of a strongly-expressed late gene of cowpox virus contain 5'-terminal poly(A) sequences. 
  • Metazoan operons accelerate recovery from growth-arrested states. 
  • Microbiota modulate transcription in the intestinal epithelium without remodeling the accessible chromatin landscape. 
  • Minimal and inducible regulation of tissue factor pathway inhibitor-2 in human gliomas. 
  • Mining the complexities of the estrogen signaling pathways for novel therapeutics. 
  • Mitochondrial transcription factor A induction by redox activation of nuclear respiratory factor 1. 
  • Modulation of RNA polymerase II elongation efficiency by C-terminal heptapeptide repeat domain kinase I. 
  • Modulation of coreceptor transcription during positive selection dictates lineage fate independently of TCR/coreceptor specificity. 
  • Modulation of estrogen receptor-alpha transcriptional activity by the coactivator PGC-1. 
  • Modulation of oncogene and tumor suppressor gene expression in a hamster model of chronic lung injury with varying degrees of pulmonary neuroendocrine cell hyperplasia. 
  • Molecular analysis of P16(Ink4)/CDKN2 and P15(INK4B)/MTS2 genes in primary human testicular germ cell tumors. 
  • Molecular characterization of hypoxia-hypothermia-conditioned human endothelial cells and their interaction with human monocytes. 
  • Molecular cloning and characterization of a novel histone deacetylase HDAC10. 
  • Molecular cloning of a cDNA of a camptothecin-resistant human DNA topoisomerase I and identification of mutation sites. 
  • Molecular cloning of ovomucoid gene sequences from partially purified ovomucoid messenger RNA. 
  • Molecular cloning of rat glucose-dependent insulinotropic peptide (GIP). 
  • Molecular cloning of the cDNA and promoter sequences for the mouse sodium-hydrogen exchanger regulatory factor. 
  • Molecular diagnosis of Burkitt's lymphoma. 
  • Molecular evaluation of BK polyomavirus nephropathy. 
  • Molecular hallmarks of endogenous chromatin complexes containing master regulators of hematopoiesis. 
  • Molecular mechanism of fibronectin gene activation by cyclic stretch in vascular smooth muscle cells. 
  • Molecular structure and function of the novel BrnT/BrnA toxin-antitoxin system of Brucella abortus. 
  • Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data. 
  • Monoclonal antibodies against EGFRvIII are tumor specific and react with breast and lung carcinomas and malignant gliomas. 
  • Monocyte Polarization is Altered by Total-Body Irradiation in Male Rhesus Macaques: Implications for Delayed Effects of Acute Radiation Exposure. 
  • Multidrug resistance in ocular melanoma. 
  • Multiple potential regulatory elements in the 5' flanking region of the human alpha 1a-adrenergic receptor. 
  • Multiple transcription start sites and 5' alternate splicing of murine IL-3 receptor beta-chain transcripts. 
  • Mutagenic processing of ribonucleotides in DNA by yeast topoisomerase I. 
  • Mutant and wild-type androgen receptors exhibit cross-talk on androgen-, glucocorticoid-, and progesterone-mediated transcription. 
  • Mutation analysis of the THRA1 gene in breast cancer: deletion/fusion of the gene to a novel sequence on 17q in the BT474 cell line. 
  • Mutation of MeCP2 alters transcriptional regulation of select immediate-early genes. 
  • Mutation-specific pathophysiological mechanisms define different neurodevelopmental disorders associated with SATB1 dysfunction. 
  • Mutational analysis of the lysyl hydroxylase 1 gene (PLOD) in six unrelated patients with Ehlers-Danlos syndrome type VI: prenatal exclusion of this disorder in one family. 
  • Mutations in exon 3 of the glycogen debranching enzyme gene are associated with glycogen storage disease type III that is differentially expressed in liver and muscle. 
  • Myc controls transcriptional regulation of cardiac metabolism and mitochondrial biogenesis in response to pathological stress in mice. 
  • Myocardial remodelling and matrix metalloproteinases in heart failure: turmoil within the interstitium. 
  • Myotilin is mutated in limb girdle muscular dystrophy 1A. 
  • N-methyl-D-aspartate receptors activate transcription of c-fos and NGFI-A by distinct phospholipase A2-requiring intracellular signaling pathways. 
  • NADH inhibition of SIRT1 links energy state to transcription during time-restricted feeding. 
  • NAFLD is associated with methylation shifts with relevance for the expression of genes involved in lipoprotein particle composition. 
  • NCP activates chloroplast transcription by controlling phytochrome-dependent dual nuclear and plastidial switches. 
  • NF-kappa B and transcriptional control of renal epithelial-inducible nitric oxide synthase. 
  • NF-kappaB cis-acting motifs of the human immunodeficiency virus (HIV) long terminal repeat regulate HIV transcription in human macrophages. 
  • NF-κB- and AP-1-mediated DNA looping regulates osteopontin transcription in endotoxin-stimulated murine macrophages. 
  • NRF2 activation promotes the recurrence of dormant tumour cells through regulation of redox and nucleotide metabolism. 
  • Neocentromeres: a place for everything and everything in its place. 
  • Neonatal Rhesus Macaques Have Distinct Immune Cell Transcriptional Profiles following HIV Envelope Immunization. 
  • Nerve activity-dependent modulation of calcineurin signaling in adult fast and slow skeletal muscle fibers. 
  • Netrin-1 and peripheral nerve regeneration in the adult rat. 
  • Network building: transcriptional circuits in the root. 
  • Network calisthenics: control of E2F dynamics in cell cycle entry. 
  • Network motifs are enriched with transcription factors whose transcripts have short half-lives. 
  • Neurobiological functions of transcriptional enhancers. 
  • Neurotrophins: peripherally and centrally acting modulators of tactile stimulus-induced inflammatory pain hypersensitivity. 
  • New genetic loci link adipose and insulin biology to body fat distribution. 
  • Next-generation sequencing of apoptotic DNA breakpoints reveals association with actively transcribed genes and gene translocations. 
  • Nitric oxide and acetaminophen-mediated oxidative injury: modulation of interleukin-1-induced nitric oxide synthesis in cultured rat hepatocytes. 
  • Nitric oxide inhibits expression of cytochrome B in endotoxin-stimulated murine macrophages. 
  • Nitric oxide production and nitric oxide synthase type 2 expression by human mononuclear phagocytes: a review. 
  • Nitric oxide-associated regulation of hepatocyte glutathione synthesis is a guanylyl cyclase-independent event. 
  • Nitric oxide-dependent osteopontin expression induces metastatic behavior in HepG2 cells. 
  • Nitric oxide-dependent ribosomal RNA cleavage is associated with inhibition of ribosomal peptidyl transferase activity in ANA-1 murine macrophages. 
  • Nitrosative stress-induced apoptosis through inhibition of NF-kappa B. 
  • Noncoding Transcription Is a Driving Force for Nucleosome Instability in spt16 Mutant Cells. 
  • Noncoding transcription controls downstream promoters to regulate T-cell receptor alpha recombination. 
  • Novel Sfp1 transcriptional regulation of Saccharomyces cerevisiae gene expression changes during spaceflight. 
  • Novel transcriptional activities of vitamin E: inhibition of cholesterol biosynthesis. 
  • Nuclear factor erythroid-derived factor 2-related factor 2 regulates transcription of CCAAT/enhancer-binding protein β during adipogenesis. 
  • Nuclear protein CBP is a coactivator for the transcription factor CREB. 
  • Nuclear receptor LXRalpha is involved in cAMP-mediated human renin gene expression. 
  • Nuclear responses to depletion of mitochondrial DNA in human cells. 
  • Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy. 
  • Ocular mucosal CD11b+ and CD103+ mouse dendritic cells under normal conditions and in allergic immune responses. 
  • Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism. 
  • Ontogeny and oncogenesis balance the transcriptional profile of renal cell cancer. 
  • Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity. 
  • Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function. 
  • Organizing mRNA export. 
  • Ornithine Decarboxylase in Macrophages Exacerbates Colitis and Promotes Colitis-Associated Colon Carcinogenesis by Impairing M1 Immune Responses. 
  • Oscillating gene expression determines competence for periodic Arabidopsis root branching. 
  • Osteopontin induces ubiquitin-dependent degradation of STAT1 in RAW264.7 murine macrophages. 
  • Osteopontin inhibits expression of cytochrome c oxidase in RAW 264.7 murine macrophages. 
  • Overexpression of TAR sequences renders cells resistant to human immunodeficiency virus replication. 
  • Overexpression of urokinase-type plasminogen activator in pancreatic adenocarcinoma is regulated by constitutively activated RelA. 
  • Overlapping transcription units in the transient receptor potential locus of Drosophila melanogaster. 
  • Oxidative and excitatory mechanisms of developmental neurotoxicity: transcriptional profiles for chlorpyrifos, diazinon, dieldrin, and divalent nickel in PC12 cells. 
  • Oxidative stress increases hepatocyte iNOS gene transcription and promoter activity. 
  • PARP-1 Controls the Adipogenic Transcriptional Program by PARylating C/EBPβ and Modulating Its Transcriptional Activity. 
  • PAX3-FOXO1 fusion gene in rhabdomyosarcoma. 
  • PD-L1 is commonly expressed and transcriptionally regulated by STAT3 and MYC in ALK-negative anaplastic large-cell lymphoma. 
  • PGC-1alpha regulates a HIF2alpha-dependent switch in skeletal muscle fiber types. 
  • PGC-1α provides a transcriptional framework for synchronous neurotransmitter release from parvalbumin-positive interneurons. 
  • PGC-1α senses the CBC of pre-mRNA to dictate the fate of promoter-proximally paused RNAPII. 
  • PITK, a PP1 targeting subunit that modulates the phosphorylation of the transcriptional regulator hnRNP K. 
  • PKA, PKC, and the protein phosphatase 2A influence HAND factor function: a mechanism for tissue-specific transcriptional regulation. 
  • PRD-2 mediates clock-regulated perinuclear localization of clock gene RNAs within the circadian cycle of Neurospora. 
  • Pairing of competitive and topologically distinct regulatory modules enhances patterned gene expression. 
  • Parathyroid hormone-related peptide represses chondrocyte hypertrophy through a protein phosphatase 2A/histone deacetylase 4/MEF2 pathway. 
  • Pathogen Evasion of Chemokine Response Through Suppression of CXCL10. 
  • Patterns of expression of murine Vgr-1 and BMP-2a RNA suggest that transforming growth factor-beta-like genes coordinately regulate aspects of embryonic development. 
  • Patterns of flanking sequence conservation and a characteristic upstream motif for microRNA gene identification. 
  • Peptide antagonists of the human estrogen receptor. 
  • Peripheral and central mechanisms of inflammatory pain, with emphasis on MAP kinases. 
  • Peripherally derived macrophages can engraft the brain independent of irradiation and maintain an identity distinct from microglia. 
  • Peritoneal and subperitoneal stroma may facilitate regional spread of ovarian cancer. 
  • Peroxisome proliferator-activated receptor gamma negatively regulates IFN-beta production in Toll-like receptor (TLR) 3- and TLR4-stimulated macrophages by preventing interferon regulatory factor 3 binding to the IFN-beta promoter. 
  • Peroxisome proliferator-activated receptor-alpha regulates fatty acid utilization in primary human skeletal muscle cells. 
  • Phage T3 DNA contains an exact copy of the 23 base-pair phage T7 RNA polymerase promoter sequence. 
  • Phosphorylated MED1 links transcription recycling and cancer growth. 
  • Phosphorylation and functions of the RNA polymerase II CTD. 
  • Phosphorylation dependence of the initiation of productive transcription of Balbiani ring 2 genes in living cells. 
  • Phosphorylation of RNA polymerase II C-terminal domain and transcriptional elongation. 
  • Phosphorylation of Ser158 regulates inflammatory redox-dependent hepatocyte nuclear factor-4alpha transcriptional activity. 
  • Phosphorylation of the group A Streptococcal CovR response regulator causes dimerization and promoter-specific recruitment by RNA polymerase. 
  • Phosphorylation of the rRNA transcription factor upstream binding factor promotes its association with TATA binding protein. 
  • Photosynthesis genes in marine viruses yield proteins during host infection. 
  • Phycomyces MADB interacts with MADA to form the primary photoreceptor complex for fungal phototropism. 
  • Phylogenetic utility of indels within ribosomal DNA and beta-tubulin sequences from fungi in the Rhizoctonia solani species complex. 
  • Physiological genomics of human arteries: quantitative relationship between gene expression and arterial stiffness. 
  • Pol II docking and pausing at growth and stress genes in C. elegans. 
  • Polarized monocyte response to cytokine stimulation. 
  • Polycistronic vesicular stomatitis virus RNA transcripts. 
  • Polycystic kidney disease in SBM transgenic mice: role of c-myc in disease induction and progression. 
  • Polymerase chain reaction detection of the BCR-ABL fusion transcript after allogeneic marrow transplantation for chronic myeloid leukemia: results and implications in 346 patients. 
  • Population perspectives on functional genomic variation in yeast. 
  • Positive patches and negative noodles: linking RNA processing to transcription? 
  • Positive regulation of the vitamin D receptor by its cognate ligand in heterologous expression systems. 
  • Post-transcriptional gene regulation by HuR promotes a more tumorigenic phenotype. 
  • Post-transcriptional inhibition of lipopolysaccharide-induced expression of inducible nitric oxide synthase by Gö6976 in murine microglia. 
  • Post-transcriptional regulation of antiviral gene expression by N6-methyladenosine. 
  • Posttranslational, translational, and transcriptional responses to nitric oxide stress in Cryptococcus neoformans: implications for virulence. 
  • Posttransplant diastolic hypertension: associations with intragraft transforming growth factor-beta, endothelin, and renin transcription. 
  • Potentiation of CD3-induced expression of the linker for activation of T cells (LAT) by the calcineurin inhibitors cyclosporin A and FK506. 
  • Potentiation of progesterone receptor-mediated transcription by the immunosuppressant FK506. 
  • Preconditioning Vaccine Sites for mRNA-Transfected Dendritic Cell Therapy and Antitumor Efficacy. 
  • Pressure-mediated oligonucleotide transfection of rat and human cardiovascular tissues. 
  • Pretranslational regulation of myoglobin gene expression. 
  • Prevalence of transcription promoters within archaeal operons and coding sequences. 
  • Probing RNA Structure in Liquid-Liquid Phase Separation Using SHAPE-MaP. 
  • Profiling microRNA expression in hepatocellular carcinoma reveals microRNA-224 up-regulation and apoptosis inhibitor-5 as a microRNA-224-specific target. 
  • Programmable mutually exclusive alternative splicing for generating RNA and protein diversity. 
  • Progressive cardiac dysfunction and fibrosis in the cardiomyopathic hamster and effects of growth hormone and angiotensin-converting enzyme inhibition. 
  • Proinflammatory cytokines and ARDS pulmonary edema fluid induce CD40 on human mesenchymal stromal cells-A potential mechanism for immune modulation. 
  • Prokaryotic transcription regulators: more than just the helix-turn-helix motif. 
  • Prolactin induction of insulin gene transcription: roles of glucose and signal transducer and activator of transcription 5. 
  • Promoter logic. 
  • Promoters, enhancers, and transcription target RAG1 binding during V(D)J recombination. 
  • Promoting developmental transcription. 
  • Prostaglandin F2 alpha receptors in the human trabecular meshwork. 
  • Proteasome-mediated turnover of the transcription coactivator NPR1 plays dual roles in regulating plant immunity. 
  • Protection from mitochondrial complex II inhibition in vitro and in vivo by Nrf2-mediated transcription. 
  • Protection from nitrosative stress: a central role for microbial flavohemoglobin. 
  • Protective responses in the ischemic myocardium. 
  • Protein expression and functional analysis of the FHIT gene in human tumor cells. 
  • Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism. 
  • Protein kinase C is a target for diverse developmental neurotoxicants: transcriptional responses to chlorpyrifos, diazinon, dieldrin and divalent nickel in PC12 cells. 
  • Protein kinase C zeta transactivates hypoxia-inducible factor alpha by promoting its association with p300 in renal cancer. 
  • Protein kinase C-mediated modulation of FIH-1 expression by the homeodomain protein CDP/Cut/Cux. 
  • Protein-DNA binding dynamics predict transcriptional response to nutrients in archaea. 
  • Proteome-wide analysis reveals widespread lysine acetylation of major protein complexes in the malaria parasite. 
  • Proteomic analysis of mitotic RNA polymerase II reveals novel interactors and association with proteins dysfunctional in disease. 
  • Proximity-dependent and proximity-independent trans-splicing in mammalian cells. 
  • Purified MotA protein binds the -30 region of a bacteriophage T4 middle-mode promoter and activates transcription in vitro. 
  • Purkinje cell degeneration associated with erythroid ankyrin deficiency in nb/nb mice. 
  • Quantitative analysis of mRNA amplification by in vitro transcription. 
  • Quantitative determination that one of two potential RNA-binding domains of the A protein component of the U1 small nuclear ribonucleoprotein complex binds with high affinity to stem-loop II of U1 RNA. 
  • Quantitative measurement of alternatively spliced amyloid precursor protein mRNA expression in Alzheimer's disease and normal brain by S1 nuclease protection analysis. 
  • Quantitative switch in integrin expression accompanies differentiation of F9 cells treated with retinoic acid. 
  • Quiescent phenotype of tumor-specific CD8+ T cells following immunization. 
  • RB regulates transcription of the p21/WAF1/CIP1 gene. 
  • RECQ5 helicase associates with the C-terminal repeat domain of RNA polymerase II during productive elongation phase of transcription. 
  • RINT-1 interacts with MSP58 within nucleoli and plays a role in ribosomal gene transcription. 
  • RNA Pol II accumulates at promoters of growth genes during developmental arrest. 
  • RNA Vaccination Therapy: Advances in an Emerging Field. 
  • RNA dynamics: it is about time. 
  • RNA polymerase from sporulating Bacillus subtilis. Purification and properties of a modified form of the enzyme containing two sporulation polypeptides. 
  • RNA polymerase-associated interactions near template promoter sequences of defective interfering particles of vesicular stomatitis virus. 
  • RNA regulons: coordination of post-transcriptional events. 
  • RNA sequence and transcriptional properties of the 3' end of the Newcastle disease virus genome. 
  • RNA sequencing of isolated cell populations expressing human APOL1 G2 risk variant reveals molecular correlates of sickle cell nephropathy in zebrafish podocytes. 
  • RNA subunit of mitochondrial RNA-processing enzyme is induced by contractile activity in striated muscle. 
  • RNA-DNA hybrid formation at a bacteriophage T4 replication origin. 
  • RNA-based analyses reveal fungal communities structured by a senescence gradient in the moss Dicranum scoparium and the presence of putative multi-trophic fungi. 
  • RNA-guided transcriptional silencing in vivo with S. aureus CRISPR-Cas9 repressors. 
  • Randomization and selection of RNA to identify targets for RRM RNA-binding proteins and antibodies. 
  • Rank order metrics for quantifying the association of sequence features with gene regulation. 
  • Rapamycin induces the G0 program of transcriptional repression in yeast by interfering with the TOR signaling pathway. 
  • Rapid 16S ribosomal DNA sequencing from a single colony without DNA extraction or purification. 
  • Rapid and transient localization of the leader RNA of vesicular stomatitis virus in the nuclei of infected cells. 
  • Rapid up-regulation of peptide elongation factor EF-1alpha protein levels is an immediate early event during oxidative stress-induced apoptosis. 
  • Ras induces p21Cip1/Waf1 cyclin kinase inhibitor transcriptionally through Sp1-binding sites. 
  • Reciprocal gut microbiota transplants from zebrafish and mice to germ-free recipients reveal host habitat selection. 
  • Recognition of multiple drugs by a single protein: a trivial solution of an old paradox. 
  • Reconciling conflicting models for global control of cell-cycle transcription. 
  • Reconstitution of the vitamin D-responsive osteocalcin transcription unit in Saccharomyces cerevisiae. 
  • Reconstructing regulatory network transitions. 
  • Reconstructing the temporal ordering of biological samples using microarray data. 
  • Recruitment of CREB binding protein is sufficient for CREB-mediated gene activation. 
  • Recruitment of endoplasmic reticulum-targeted and cytosolic mRNAs into membrane-associated stress granules. 
  • Redeployment of Myc and E2f1-3 drives Rb-deficient cell cycles. 
  • Redox rhythm reinforces the circadian clock to gate immune response 
  • Redox-mediated upregulation of hepatocyte iNOS transcription requires coactivator PC4. 
  • Reduced expression of TGF beta1RII in agnogenic myeloid metaplasia is not due to mutation or methylation. 
  • Reduced expression of transforming growth factor beta type I receptor contributes to the malignancy of human colon carcinoma cells. 
  • Reduced growth, abnormal kidney structure, and type 2 (AT2) angiotensin receptor-mediated blood pressure regulation in mice lacking both AT1A and AT1B receptors for angiotensin II. 
  • Reduced reperfusion-induced Ins(1,4,5)P3 generation and arrhythmias in hearts expressing constitutively active alpha1B-adrenergic receptors. 
  • Regional rearrangements in chromosome 15q21 cause formation of cryptic promoters for the CYP19 (aromatase) gene. 
  • Regulating the regulator: NF-kappaB signaling in heart. 
  • Regulation and function of the calcium/calmodulin-dependent protein kinase IV/protein serine/threonine phosphatase 2A signaling complex. 
  • Regulation of Co-transcriptional Pre-mRNA Splicing by m⁶ A through the Low-Complexity Protein hnRNPG. 
  • Regulation of E2A activities by histone acetyltransferases in B lymphocyte development. 
  • Regulation of Frizzled by fat-like cadherins during planar polarity signaling in the Drosophila compound eye. 
  • Regulation of I-309 gene expression in human monocytes by endogenous interleukin-1. 
  • Regulation of MEF2 by histone deacetylase 4- and SIRT1 deacetylase-mediated lysine modifications. 
  • Regulation of MUC5AC expression by NAD(P)H:quinone oxidoreductase 1. 
  • Regulation of T cell receptor alpha gene assembly by a complex hierarchy of germline Jalpha promoters. 
  • Regulation of T cell receptor beta allelic exclusion at a level beyond accessibility. 
  • Regulation of T cell receptor delta gene rearrangement by c-Myb. 
  • Regulation of T cell receptor-alpha gene recombination by transcription. 
  • Regulation of TCR delta and alpha repertoires by local and long-distance control of variable gene segment chromatin structure. 
  • Regulation of alpha-synuclein expression: implications for Parkinson's disease. 
  • Regulation of biliary secretion through apical purinergic receptors in cultured rat cholangiocytes. 
  • Regulation of cholecystokinin gene expression in rat intestine. 
  • Regulation of cholecystokinin synthesis and secretion in rat intestine. 
  • Regulation of chondrocytic gene expression by biomechanical signals. 
  • Regulation of chromatin accessibility and Zic binding at enhancers in the developing cerebellum. 
  • Regulation of chromatin accessibility for V(D)J recombination. 
  • Regulation of cytokine production in the human thymus: epidermal growth factor and transforming growth factor alpha regulate mRNA levels of interleukin 1 alpha (IL-1 alpha), IL-1 beta, and IL-6 in human thymic epithelial cells at a post-transcriptional level. 
  • Regulation of gonadotropin-releasing hormone by protein kinase-A and -C in immortalized hypothalamic neurons. 
  • Regulation of growth-defense balance by the JASMONATE ZIM-DOMAIN (JAZ)-MYC transcriptional module. 
  • Regulation of interleukin-8 expression by cellular pH in human pancreatic adenocarcinoma cells. 
  • Regulation of lipoprotein synthesis. Studies on the molecular mechanisms of lipoprotein synthesis and their regulation by estrogen in the cockerel. 
  • Regulation of phospholipid biosynthesis in Escherichia coli. Cloning of the structural gene for the biosynthetic sn-glycerol-3-phosphate dehydrogenase. 
  • Regulation of the T-cell receptor delta enhancer by functional cooperation between c-Myb and core-binding factors. 
  • Regulation of the beta 2-adrenergic receptor and its mRNA in the rat ventral prostate by testosterone. 
  • Regulation of transcription of the repA1 gene in the replication control region of IncFII plasmid NR1 by gene dosage of the repA2 transcription repressor protein. 
  • Regulation of vascular endothelial growth factor expression by acidosis in human cancer cells. 
  • Regulation of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF-A) expression in podocytes. 
  • Regulator of G protein signaling 5 is highly expressed in parathyroid tumors and inhibits signaling by the calcium-sensing receptor. 
  • Regulatory cascades involving calmodulin-dependent protein kinases. 
  • Regulatory elements governing transcription in specialized myofiber subtypes. 
  • RelB modulation of IkappaBalpha stability as a mechanism of transcription suppression of interleukin-1alpha (IL-1alpha), IL-1beta, and tumor necrosis factor alpha in fibroblasts. 
  • Relationship between expression of coactivators and corepressors of hormone receptors and resistance of ovarian cancers to growth regulation by steroid hormones. 
  • Relationship of acivicin-induced monocytoid differentiation of human myeloid leukemia cells to acivicin-induced modulation of growth factor, cytokine, and protooncogene mRNA expression. 
  • Reliability of transcriptional cycles and the yeast cell-cycle oscillator. 
  • Remodeling of global transcription patterns of Cryptococcus neoformans genes mediated by the stress-activated HOG signaling pathways. 
  • Renal cell carcinoma development in the rat independent of alterations at the VHL gene locus. 
  • Repetitive transcranial magnetic stimulation activates specific regions in rat brain. 
  • Replication and preferential inheritance of hypersuppressive petite mitochondrial DNA. 
  • Replication of the Escherichia coli chromosome in RNase HI-deficient cells: multiple initiation regions and fork dynamics. 
  • Replication of the vesicular stomatitis virus genome in permissive and nonpermissive host cells. 
  • Repression of yeast Ste12 transcription factor by direct binding of unphosphorylated Kss1 MAPK and its regulation by the Ste7 MEK. 
  • Research resource: Transcriptional profiling in a cellular model of breast cancer reveals functional and mechanistic differences between clinically relevant SERM and between SERM/estrogen complexes. 
  • Research resource: nuclear receptor atlas of human retinal pigment epithelial cells: potential relevance to age-related macular degeneration. 
  • Resistance to dual blockade of the kinases PI3K and mTOR in KRAS-mutant colorectal cancer models results in combined sensitivity to inhibition of the receptor tyrosine kinase EGFR. 
  • Results from a human renal allograft tolerance trial evaluating T-cell depletion with alemtuzumab combined with deoxyspergualin. 
  • Retroviral E-DNA: persistence and gene expression in nondividing immune cells. 
  • Retroviral vector gene expression in F9 embryonal carcinoma cells. 
  • Retroviruses and human cancer: evaluation of T-lymphocyte transformation by human T-cell leukemia-lymphoma virus. 
  • Reverse genetics of Drosophila RNA polymerase II: identification and characterization of RpII140, the genomic locus for the second-largest subunit. 
  • Revertants and partial transformants of rat fibroblasts infected with Fujinami sarcoma virus. 
  • Revising messages traveling along the cellular information superhighway. 
  • Rho GTPase activity modulates Wnt3a/beta-catenin signaling. 
  • Ribonucleoprotein infrastructure regulating the flow of genetic information between the genome and the proteome. 
  • Ribonucleotides and Transcription-Associated Mutagenesis in Yeast. 
  • Ribosomal protein S4 acts in trans as a translational repressor to regulate expression of the alpha operon in Escherichia coli. 
  • Ribozyme-mediated repair of RNAs encoding mutant tumor suppressors. 
  • Role for topoisomerase 1 in transcription-associated mutagenesis in yeast. 
  • Role of MotA transcription factor in bacteriophage T4 DNA replication. 
  • Role of hypoxia in inflammatory upper airway disease. 
  • S-nitrosylation in the regulation of gene transcription. 
  • S-nitrosylation of heterogeneous nuclear ribonucleoprotein A/B regulates osteopontin transcription in endotoxin-stimulated murine macrophages. 
  • SB-431542, a small molecule transforming growth factor-beta-receptor antagonist, inhibits human glioma cell line proliferation and motility. 
  • SFRP2 regulates cardiomyogenic differentiation by inhibiting a positive transcriptional autofeedback loop of Wnt3a. 
  • SHP-1 as a critical regulator of Mycoplasma pneumoniae-induced inflammation in human asthmatic airway epithelial cells. 
  • STAT1-induced ASPP2 transcription identifies a link between neuroinflammation, cell polarity, and tumor suppression. 
  • SV40 enhancer-binding factors are required at the establishment but not the maintenance step of enhancer-dependent transcriptional activation. 
  • Sakacin P non-producing Lactobacillus sakei strains contain homologues of the sakacin P gene cluster. 
  • Salmonella Activation of STAT3 Signaling by SarA Effector Promotes Intracellular Replication and Production of IL-10. 
  • Satellite DNA is transcribed on lampbrush chromosomes. 
  • Searching for transcriptional regulators of Ang II-induced vascular pathology. 
  • Selection of an RNA molecule that mimics a major autoantigenic epitope of human insulin receptor. 
  • Sequence and chromosomal location of the I-309 gene. Relationship to genes encoding a family of inflammatory cytokines. 
  • Sequence and expression of zebrafish foxc1a and foxc1b, encoding conserved forkhead/winged helix transcription factors. 
  • Sequence elements required for transcriptional activity of the human myoglobin promoter in intact myocardium. 
  • Sequence specificity incompletely defines the genome-wide occupancy of Myc. 
  • Sequences that direct rat tyrosine hydroxylase gene expression. 
  • Sequences within the coding regions of clotting factor VIII and CFTR block transcriptional elongation. 
  • Sequential activation of splenic nuclear RNA polymerases by erythropoietin. 
  • Sequential synthesis of small capped RNA transcripts in vitro by vesicular stomatitis virus. 
  • Shaping Chromatin States in Prostate Cancer by Pioneer Transcription Factors. 
  • Short-term integration of Cdc25 dynamics controls mitotic entry during Drosophila gastrulation. 
  • Signal transduction in cardiac hypertrophy--dissecting compensatory versus pathological pathways utilizing a transgenic approach. 
  • Signaling repression of transcription by RNA polymerase III in yeast. 
  • Simian virus 40 transcriptional complexes incorporate mercurated nucleotides into RNA in vitro. 
  • Single cell RNA-seq reveals profound transcriptional similarity between Barrett's oesophagus and oesophageal submucosal glands. 
  • Single transcriptional and translational preQ1 riboswitches adopt similar pre-folded ensembles that follow distinct folding pathways into the same ligand-bound structure. 
  • Single-Cell Analysis of Quiescent HIV Infection Reveals Host Transcriptional Profiles that Regulate Proviral Latency. 
  • Sir2 suppresses transcription-mediated displacement of Mcm2-7 replicative helicases at the ribosomal DNA repeats. 
  • Slip into something more functional: selection maintains ancient frameshifts in homopolymeric sequences. 
  • Slow nucleosome dynamics set the transcriptional speed limit and induce RNA polymerase II traffic jams and bursts. 
  • Slow-release nanoparticle-encapsulated delivery system for laryngeal injection. 
  • Smoothelin-like 1 protein is a bifunctional regulator of the progesterone receptor during pregnancy. 
  • Smoothened signaling in vertebrates is facilitated by a G protein-coupled receptor kinase. 
  • Sodium regulation of angiotensinogen mRNA expression in rat kidney cortex and medulla. 
  • Somatic mutations in the transcriptional corepressor gene BCORL1 in adult acute myelogenous leukemia. 
  • Somatic single hits inactivate the X-linked tumor suppressor FOXP3 in the prostate. 
  • Spatial encoding of cyclic AMP signaling specificity by GPCR endocytosis. 
  • Specific blockade of basic fibroblast growth factor gene expression in endothelial cells by antisense oligonucleotide. 
  • Specific chemopreventive agents trigger proteasomal degradation of G1 cyclins: implications for combination therapy. 
  • Specific nuclear binding of adenosine 3',5'-monophosphate-binding protein complex with subsequent poly(A) RNA synthesis in embryonic chick cartilage. 
  • Spontaneous development of endoplasmic reticulum stress that can lead to diabetes mellitus is associated with higher calcium-independent phospholipase A2 expression: a role for regulation by SREBP-1. 
  • Stable expression of transdominant Rev protein in human T cells inhibits human immunodeficiency virus replication. 
  • Steroid and high-temperature induction of the small heat-shock protein genes in Drosophila. 
  • Steroid hormone receptors selectively affect transcriptional activation but not basal repression by thyroid hormone receptors. 
  • Steroid hormone regulation of specific gene expression. 
  • Steroid hormone regulation of specific messenger RNA and protein synthesis in eucaryotic cells. 
  • Stimulation of GCMa transcriptional activity by cyclic AMP/protein kinase A signaling is attributed to CBP-mediated acetylation of GCMa. 
  • Stimulation of cartilage macromolecule synthesis by adenosine 3',5'-monophosphate. 
  • Stimulation of cytoplasmic actin gene transcription and translation in cultured Drosophila cells by ecdysterone. 
  • Stimulation of mitotic recombination events by high levels of RNA polymerase II transcription in yeast. 
  • Structural and functional studies of cyclic GMP phosphodiesterase. 
  • Structural and transcriptional analyses of a purine nucleotide-binding protein from Pyrococcus furiosus: a component of a novel, membrane-bound multiprotein complex unique to this hyperthermophilic archaeon. 
  • Structural basis for ADP-mediated transcriptional regulation by P1 and P7 ParA. 
  • Structural basis of DNA-protein recognition. 
  • Structural characterization of the 5' regions of the human phenylalanine hydroxylase gene. 
  • Structural domains that contribute to substrate specificity in facilitated glucose transporters are distinct from those involved in kinetic function: studies with GLUT-1/GLUT-2 chimeras. 
  • Structural mechanism of transcription regulation of the Staphylococcus aureus multidrug efflux operon mepRA by the MarR family repressor MepR. 
  • Structure and evolution of prokaryotic and eukaryotic RNA polymerases: a model. 
  • Structure and regulation of the chicken erythroid delta-aminolevulinate synthase gene. 
  • Structure and regulation of the mouse ing1 gene. Three alternative transcripts encode two phd finger proteins that have opposite effects on p53 function. 
  • Structure of the eukaryotic transcription apparatus: features of the gene for the largest subunit of Drosophila RNA polymerase II. 
  • Structure of the genes encoding transcription factor IIB and TATA box-binding protein from Drosophila melanogaster. 
  • Structure, chromosome location, and expression of the human gamma-actin gene: differential evolution, location, and expression of the cytoskeletal beta- and gamma-actin genes. 
  • Structures of BmrR-drug complexes reveal a rigid multidrug binding pocket and transcription activation through tyrosine expulsion. 
  • Studies of the regulatory mechanism of Ca2+/calmodulin-dependent protein kinase II. Mutation of threonine 286 to alanine and aspartate. 
  • Studies on the repression of basal transcription (silencing) by artificial and natural human thyroid hormone receptor-beta mutants. 
  • Substitutions in bacteriophage T4 AsiA and Escherichia coli sigma(70) that suppress T4 motA activation mutations. 
  • Superoxide dismutase-3 promotes full expression of the EPO response to hypoxia. 
  • Superoxide enhances interleukin 1beta-mediated transcription of the hepatocyte-inducible nitric oxide synthase gene. 
  • Suppression of CHK1 by ETS Family Members Promotes DNA Damage Response Bypass and Tumorigenesis. 
  • Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor. 
  • Suppression of the microRNA pathway by bacterial effector proteins. 
  • Synaptic, transcriptional and chromatin genes disrupted in autism. 
  • Synergistic interactions between heterologous upstream activation elements and specific TATA sequences in a muscle-specific promoter. 
  • Synthetic LXXLL peptide antagonize 1,25-dihydroxyvitamin D3-dependent transcription. 
  • Systematic analysis of F-box proteins reveals a new branch of the yeast mating pathway. 
  • Systems approaches to identifying gene regulatory networks in plants. 
  • Systems biology approaches to defining transcription regulatory networks in halophilic archaea. 
  • Systems proteomics of cardiac chromatin identifies nucleolin as a regulator of growth and cellular plasticity in cardiomyocytes. 
  • T cell CD7 mRNA expression is regulated by both transcriptional and post-transcriptional mechanisms. 
  • T cell activation up-regulates the expression of the focal adhesion kinase Pyk2: opposing roles for the activation of protein kinase C and the increase in intracellular Ca2+. 
  • T-cell receptor α enhancer is inactivated in αβ T lymphocytes. 
  • TAFII70 isoform-specific growth suppression correlates with its ability to complex with the GADD45a protein. 
  • TCF1 Is Required for the T Follicular Helper Cell Response to Viral Infection. 
  • TOR controls transcriptional and translational programs via Sap-Sit4 protein phosphatase signaling effectors. 
  • Tagging ribozyme reaction sites to follow trans-splicing in mammalian cells. 
  • Targeted inactivation of the EGF and amphiregulin genes reveals distinct roles for EGF receptor ligands in mouse mammary gland development. 
  • Targeted inhibition of V(D)J recombination by a histone methyltransferase. 
  • Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells. 
  • Tat-SF1 is not required for Tat transactivation but does regulate the relative levels of unspliced and spliced HIV-1 RNAs. 
  • Tbx5 and Tbx20 act synergistically to control vertebrate heart morphogenesis. 
  • Techniques used to study transcription on chromatin templates. 
  • Temperature-dependent sex determination is mediated by pSTAT3 repression of Kdm6b. 
  • Temperature-sensitive mRNA degradation is an early event in hepatocyte de-differentiation. 
  • Temporal and tissue-specific expression of distinct retrovirus-like (VL30) elements during mouse development. 
  • Temporally regulated nuclear entry of the Drosophila period protein contributes to the circadian clock. 
  • Tenascin-C inhibits extracellular matrix-dependent gene expression in mammary epithelial cells. Localization of active regions using recombinant tenascin fragments. 
  • The 5' non-coding region of the BCR/ABL oncogene augments its ability to stimulate the growth of immature lymphoid cells. 
  • The 58-kda microspherule protein (MSP58) represses human telomerase reverse transcriptase (hTERT) gene expression and cell proliferation by interacting with telomerase transcriptional element-interacting factor (TEIF). 
  • The 70-kDa heat shock cognate protein (Hsc73) gene is enhanced by ovarian hormones in the ventromedial hypothalamus. 
  • The A and B isoforms of the human progesterone receptor operate through distinct signaling pathways within target cells. 
  • The ABL2 kinase regulates an HSF1-dependent transcriptional program required for lung adenocarcinoma brain metastasis. 
  • The AZFc region of the Y chromosome features massive palindromes and uniform recurrent deletions in infertile men. 
  • The Alzheimer's associated 5' region of the SORL1 gene cis regulates SORL1 transcripts expression. 
  • The Arabidopsis RGA gene encodes a transcriptional regulator repressing the gibberellin signal transduction pathway. 
  • The Aryl Hydrocarbon Receptor: A Mediator and Potential Therapeutic Target for Ocular and Non-Ocular Neurodegenerative Diseases. 
  • The C-terminal repeat domain of RNA polymerase II largest subunit is essential in vivo but is not required for accurate transcription initiation in vitro. 
  • The Cryptococcus neoformans capsule: a sword and a shield. 
  • The DAZ gene cluster on the human Y chromosome arose from an autosomal gene that was transposed, repeatedly amplified and pruned. 
  • The DNA damage- and transcription-associated protein paxip1 controls thymocyte development and emigration. 
  • The Drosophila Translational Control Element (TCE) is required for high-level transcription of many genes that are specifically expressed in testes. 
  • The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal. 
  • The ERF11 Transcription Factor Promotes Internode Elongation by Activating Gibberellin Biosynthesis and Signaling. 
  • The Ess1 prolyl isomerase is linked to chromatin remodeling complexes and the general transcription machinery. 
  • The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling. 
  • The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer. 
  • The LS locus of pea encodes the gibberellin biosynthesis enzyme ent-kaurene synthase A. 
  • The Local Edge Machine: inference of dynamic models of gene regulation. 
  • The MTE, a new core promoter element for transcription by RNA polymerase II. 
  • The NMDA receptor subunit GluN3A regulates synaptic activity-induced and myocyte enhancer factor 2C (MEF2C)-dependent transcription. 
  • The Novel Progesterone Receptor Antagonists RTI 3021-012 and RTI3021-022 Exhibit Complex Glucocorticoid Receptor Antagonist Activities: Implications for the Development of Dissociated Antiprogestins. 
  • The Nuclear Pore Complex in Cell Type-Specific Chromatin Structure and Gene Regulation. 
  • The Phycomyces madA gene encodes a blue-light photoreceptor for phototropism and other light responses. 
  • The RNA polymerase II CTD kinase CTDK-I affects pre-mRNA 3' cleavage/polyadenylation through the processing component Pti1p. 
  • The RNA-binding protein DND1 acts sequentially as a negative regulator of pluripotency and a positive regulator of epigenetic modifiers required for germ cell reprogramming. 
  • The Ribbon-Helix-Helix Domain Protein CdrS Regulates the Tubulin Homolog ftsZ2 To Control Cell Division in Archaea. 
  • The SCARECROW gene regulates an asymmetric cell division that is essential for generating the radial organization of the Arabidopsis root. 
  • The SV40 core sequence functions as a repressor element in yeast. 
  • The Saccharomyces and Drosophila heat shock transcription factors are identical in size and DNA binding properties. 
  • The Smads: transcriptional regulation and mouse models. 
  • The Staphylococcus aureus pSK41 plasmid-encoded ArtA protein is a master regulator of plasmid transmission genes and contains a RHH motif used in alternate DNA-binding modes. 
  • The TCT motif, a key component of an RNA polymerase II transcription system for the translational machinery. 
  • The TOR kinases link nutrient sensing to cell growth. 
  • The TOR signaling cascade regulates gene expression in response to nutrients. 
  • The TP53 tumor suppressor and autophagy in malignant lymphoma. 
  • The TetR family of transcriptional repressors. 
  • The Ties that Bind (the Igh Locus). 
  • The accessible chromatin landscape of the human genome. 
  • The activity of a highly promiscuous AP-1 element can be confined to neurons by a tissue-selective repressive element. 
  • The anatomy of microbial cell state transitions in response to oxygen. 
  • The angiotensin II type I receptor-associated protein, ATRAP, is a transmembrane protein and a modulator of angiotensin II signaling. 
  • The anti-inflammatory actions of platelet endothelial cell adhesion molecule-1 do not involve regulation of endothelial cell NF-kappa B. 
  • The antisense transcriptomes of human cells. 
  • The aryl hydrocarbon nuclear translocator alters CD30-mediated NF-kappaB-dependent transcription. 
  • The autonomous activity of calcium/calmodulin-dependent protein kinase IV is required for its role in transcription. 
  • The bHLH transcription factor POPEYE regulates response to iron deficiency in Arabidopsis roots. 
  • The biochemistry and molecular biology of glucocorticoid-induced apoptosis in the immune system. 
  • The carboxyl-terminal repeat domain of RNA polymerase II is not required for transcription factor Sp1 to function in vitro. 
  • The cell-cycle transcriptional network generates and transmits a pulse of transcription once each cell cycle. 
  • The circadian regulatory proteins BMAL1 and cryptochromes are substrates of casein kinase Iepsilon. 
  • The claret locus in Drosophila encodes products required for eyecolor and for meiotic chromosome segregation. 
  • The clinical significance of tenascin-C splice variant expression in chondrosarcoma. 
  • The compact chromatin structure of a Ty repeated sequence suppresses recombination hotspot activity in Saccharomyces cerevisiae. 
  • The complete sequence of a unique RNA species synthesized by a DI particle of VSV. 
  • The crystal structure of the RsbN-σBldN complex from Streptomyces venezuelae defines a new structural class of anti-σ factor. 
  • The cyclic AMP response element directs tyrosine hydroxylase expression in catecholaminergic central and peripheral nervous system cell lines from transgenic mice. 
  • The downstream core promoter element, DPE, is conserved from Drosophila to humans and is recognized by TAFII60 of Drosophila. 
  • The effect of osmotic stress on the production of nukacin ISK-1 from Staphylococcus warneri ISK-1. 
  • The effects of ascorbic acid on cartilage metabolism in guinea pig articular cartilage explants. 
  • The endogenous immunoglobulin heavy chain enhancer can activate tandem VH promoters separated by a large distance. 
  • The estrogen receptor beta-isoform (ERbeta) of the human estrogen receptor modulates ERalpha transcriptional activity and is a key regulator of the cellular response to estrogens and antiestrogens. 
  • The evolution of transcriptional regulation in eukaryotes. 
  • The exoribonuclease Xrn1 is a post-transcriptional negative regulator of autophagy. 
  • The fast and transient transcriptional network of gravity and mechanical stimulation in the Arabidopsis root apex. 
  • The forkhead transcription factor FoxI1 remains bound to condensed mitotic chromosomes and stably remodels chromatin structure. 
  • The gamma2 late glycoprotein K promoter of equine herpesvirus 1 is differentially regulated by the IE and EICP0 proteins. 
  • The gene coding for the Hrp pilus structural protein is required for type III secretion of Hrp and Avr proteins in Pseudomonas syringae pv. tomato. 
  • The genome of a songbird. 
  • The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans. 
  • The global dynamics of RNA stability orchestrates responses to cellular activation. 
  • The histone deacetylase HDAC4 connects neural activity to muscle transcriptional reprogramming. 
  • The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote. 
  • The human CYP19 (aromatase P450) gene: update on physiologic roles and genomic organization of promoters. 
  • The human gene for mannan-binding lectin-associated serine protease-2 (MASP-2), the effector component of the lectin route of complement activation, is part of a tightly linked gene cluster on chromosome 1p36.2-3. 
  • The human gene for the type III isozyme of hexokinase: structure, basal promoter, and evolution. 
  • The human progesterone receptor A-form functions as a transcriptional modulator of mineralocorticoid receptor transcriptional activity. 
  • The initial nucleotide sequence of DNA transcribed from avian myeloblastosis virus 70 S RNA by RNA-dependent DNA polymerase. 
  • The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes. 
  • The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes. 
  • The mammalian HSF4 gene generates both an activator and a repressor of heat shock genes by alternative splicing. 
  • The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor. 
  • The mechanism of steroid-hormone regulation of transcription of specific eukaryotic genes. 
  • The metabolic fate of independently initiated VSV mRNA transcripts. 
  • The monomeric receptor binding domain of tetrameric α2-macroglobulin binds to cell surface GRP78 triggering equivalent activation of signaling cascades. 
  • The natural 5' splice site of simian virus 40 large T antigen can be improved by increasing the base complementarity to U1 RNA. 
  • The nicotinic acetylcholine receptor gene family of the silkworm, Bombyx mori. 
  • The nontranscribed chicken calmodulin pseudogene cross-hybridizes with mRNA from the slow-muscle troponin C gene. 
  • The nuclear corepressors NCoR and SMRT are key regulators of both ligand- and 8-bromo-cyclic AMP-dependent transcriptional activity of the human progesterone receptor. 
  • The nuclear hormone receptor coactivator SRC-1 is a specific target of p300. 
  • The ompU Paralogue vca1008 is required for virulence of Vibrio cholerae. 
  • The opposing transcriptional activities of the two isoforms of the human progesterone receptor are due to differential cofactor binding. 
  • The origin of O6-methylguanine-DNA methyltransferase in Chinese hamster ovary cells transfected with human DNA. 
  • The ovalbumin gene. Partial purification of the coding strand. 
  • The peroxisome proliferator-activated receptor alpha is a phosphoprotein: regulation by insulin. 
  • The plus strand of reovirus gene S2 is identical with its in vitro transcript. 
  • The polyphony of BACH2. 
  • The proto-oncogene bcl-3 encodes an I kappa B protein. 
  • The regulation of ferroptosis by MESH1 through the activation of the integrative stress response. 
  • The regulatory light chain of nonmuscle myosin is encoded by spaghetti-squash, a gene required for cytokinesis in Drosophila. 
  • The repression of hormone-activated PEPCK gene expression by glucose is insulin-independent but requires glucose metabolism. 
  • The robustness of the transcriptional response to alterations in morphogenetic gradients. 
  • The role of Gla proteins in vascular calcification. 
  • The role of HOM-C genes in segmental transformations: reexamination of the Drosophila Sex combs reduced embryonic phenotype. 
  • The role of NAD(P)H:quinone oxidoreductase in mitomycin C- and porfiromycin-resistant HCT 116 human colon-cancer cells. 
  • The role of Osteopontin in tumor metastasis. 
  • The role of orphan nuclear receptor in thymocyte differentiation and lymphoid organ development. 
  • The role of p53 in cell-cycle control and apoptosis: implications for cancer. 
  • The roles of steroidogenic factor-1 in reproductive function. 
  • The second-largest subunit of the poxvirus RNA polymerase is similar to the corresponding subunits of procaryotic and eucaryotic RNA polymerases. 
  • The signal sequence receptor, unlike the signal recognition particle receptor, is not essential for protein translocation. 
  • The strength and periodicity of D. melanogaster circadian rhythms are differentially affected by alterations in period gene expression. 
  • The structural organization of the chicken calmodulin gene. 
  • The structure of the trpE, trpD and 5' trpC genes of Bacillus pumilus. 
  • The transcription factor B-Myb is maintained in an inhibited state in target cells through its interaction with the nuclear corepressors N-CoR and SMRT. 
  • The transcription factor HLH-2/E/Daughterless regulates anchor cell invasion across basement membrane in C. elegans. 
  • The transcriptional response of the islet to pregnancy in mice. 
  • Therapeutic immunization protects dopaminergic neurons in a mouse model of Parkinson's disease. 
  • Thromboxane A2modulates the fibrinolytic system in glomerular mesangial cells. 
  • Thymocytes and cultured thymic epithelial cells express transcripts encoding alpha-3, alpha-5 and beta-4 subunits of neuronal nicotinic acetylcholine receptors: preferential transcription of the alpha-3 and beta-4 genes by immature CD4 + 8 + thymocytes. 
  • Thymocytes and cultured thymic epithelial cells express transcripts encoding alpha-3, alpha-5, and beta-4 subunits of neuronal nicotinic acetylcholine receptors. Preferential transcription of the alpha-3 and beta-4 genes by immature CD4+8+ thymocytes and evidence for response to nicotine in thymocytes. 
  • Thyroid hormone action at the cellular, genomic and target gene levels. 
  • Thyroid hormone negatively regulates CDX2 and SOAT2 mRNA expression via induction of miRNA-181d in hepatic cells. 
  • Tissue specificity of renin promoter activity and regulation in mice. 
  • Tissue- and strain-specific effects of a genotoxic carcinogen 1,3-butadiene on chromatin and transcription. 
  • Tissue-specific expression of the mammalian bombesin gene. 
  • Tissue-specific gene expression in mouse F9 embryonal carcinoma cells: type IV collagen. 
  • Tissue-specific transcription of the rat tyrosine hydroxylase gene requires synergy between an AP-1 motif and an overlapping E box-containing dyad. 
  • Topoisomerase 1-dependent deletions initiated by incision at ribonucleotides are biased to the non-transcribed strand of a highly activated reporter. 
  • Topoisomerase I and Genome Stability: The Good and the Bad. 
  • Topoisomerase I plays a critical role in suppressing genome instability at a highly transcribed G-quadruplex-forming sequence. 
  • Topology and control of the cell-cycle-regulated transcriptional circuitry. 
  • Tor and cyclic AMP-protein kinase A: two parallel pathways regulating expression of genes required for cell growth. 
  • Tracking transcription factor mobility and interaction in Arabidopsis roots with fluorescence correlation spectroscopy. 
  • Trans-splicing reactions by ribozymes. 
  • Transactivation functions facilitate the disruption of chromatin structure by estrogen receptor derivatives in vivo. 
  • Transcribing the connectome: roles for transcription factors and chromatin regulators in activity-dependent synapse development. 
  • Transcript length heterogeneity at the small heat shock protein genes of Drosophila. 
  • Transcription Factor-Directed Re-wiring of Chromatin Architecture for Somatic Cell Nuclear Reprogramming toward trans-Differentiation. 
  • Transcription as a source of genome instability. 
  • Transcription errors induce proteotoxic stress and shorten cellular lifespan. 
  • Transcription factor Nrg1 mediates capsule formation, stress response, and pathogenesis in Cryptococcus neoformans. 
  • Transcription factor TFII-I causes transcriptional upregulation of GRP78 synthesis in prostate cancer cells. 
  • Transcription factor decoy. 
  • Transcription factors MYOCD, SRF, Mesp1 and SMARCD3 enhance the cardio-inducing effect of GATA4, TBX5, and MEF2C during direct cellular reprogramming. 
  • Transcription factors are required for the meiotic recombination hotspot at the HIS4 locus in Saccharomyces cerevisiae. 
  • Transcription in mouse embryo cells permissively infected by murine cytomegalovirus. 
  • Transcription inhibits the replication of autonomously replicating plasmids in human cells. 
  • Transcription initiation patterns indicate divergent strategies for gene regulation at the chromatin level. 
  • Transcription interruption may be a common mechanism of c-myc regulation during HL-60 differentiation. 
  • Transcription of H-2 and Qa genes in embryonic and adult mice. 
  • Transcription of a poxvirus early gene is regulated both by a short promoter element and by a transcriptional termination signal controlling transcriptional interference. 
  • Transcription of class III genes: formation of preinitiation complexes. 
  • Transcription of orthopoxvirus telomeres at late times during infection. 
  • Transcription of spacer sequences flanking the rat 45S ribosomal DNA gene. 
  • Transcription of the RelB gene is regulated by NF-kappaB. 
  • Transcription of the SsrAB regulon is repressed by alkaline pH and is independent of PhoPQ and magnesium concentration. 
  • Transcription of the terminal loop region of vaccinia virus DNA is initiated from the telomere sequences directing DNA resolution. 
  • Transcription profiling of estrogen target genes in young and old mouse uterus. 
  • Transcription recycling assays identify PAF1 as a driver for RNA Pol II recycling. 
  • Transcription-associated mutagenesis in yeast is directly proportional to the level of gene expression and influenced by the direction of DNA replication. 
  • Transcription-associated mutagenesis. 
  • Transcription-associated mutation of lasR in Pseudomonas aeruginosa. 
  • Transcription-dependent mobilization of nucleosomes at accessible TCR gene segments in vivo. 
  • Transcription-factor-dependent enhancer transcription defines a gene regulatory network for cardiac rhythm. 
  • Transcriptional Circuit Fragility Influences HIV Proviral Fate. 
  • Transcriptional Profiling of Somatostatin Interneurons in the Spinal Dorsal Horn. 
  • Transcriptional Regulation in Archaea: From Individual Genes to Global Regulatory Networks. 
  • Transcriptional Regulation of SDHa flavoprotein by nuclear respiratory factor-1 prevents pseudo-hypoxia in aerobic cardiac cells. 
  • Transcriptional Timers Regulating Mitosis in Early Drosophila Embryos. 
  • Transcriptional activation of the IL-6 gene in human contracting skeletal muscle: influence of muscle glycogen content. 
  • Transcriptional analysis of tumor-specific T-cell responses in cancer patients. 
  • Transcriptional and posttranscriptional regulation of cytokine gene expression in HIV-1 antigen-specific CD8+ T cells that mediate virus inhibition. 
  • Transcriptional and posttranscriptional regulation of transcription factor expression in Arabidopsis roots. 
  • Transcriptional attenuation following cAMP induction requires PP-1-mediated dephosphorylation of CREB. 
  • Transcriptional biomarkers distinguish between vulnerable periods for developmental neurotoxicity of chlorpyrifos: Implications for toxicogenomics. 
  • Transcriptional brakes on the road to adipocyte thermogenesis. 
  • Transcriptional components of anteroposterior positional information during zebrafish fin regeneration. 
  • Transcriptional control of cognitive development. 
  • Transcriptional control of erythropoiesis. 
  • Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation. 
  • Transcriptional control of intestinal cytochrome P-4503A by 1alpha,25-dihydroxy vitamin D3. 
  • Transcriptional control of mitochondrial biogenesis and its interface with inflammatory processes. 
  • Transcriptional control of tissue formation throughout root development. 
  • Transcriptional diversity and bioenergetic shift in human breast cancer metastasis revealed by single-cell RNA sequencing. 
  • Transcriptional down-regulation of tumor necrosis factor-alpha gene expression by a synthetic peptide homologous to retroviral envelope protein. 
  • Transcriptional enhancer elements in the mouse immunoglobulin heavy chain locus. 
  • Transcriptional inhibition by carcinogenic chromate: relationship to DNA damage. 
  • Transcriptional network of multiple capsule and melanin genes governed by the Cryptococcus neoformans cyclic AMP cascade. 
  • Transcriptional networks controlling plant development. 
  • Transcriptional pausing in a region important for plasmid NR1 replication control. 
  • Transcriptional profiles of JIA patient blood with subsequent poor response to methotrexate. 
  • Transcriptional profiles reveal similarities and differences in the effects of developmental neurotoxicants on differentiation into neurotransmitter phenotypes in PC12 cells. 
  • Transcriptional profiling of whole blood and serum protein analysis of mice exposed to the neurotoxin Pacific Ciguatoxin-1. 
  • Transcriptional programmes underlying cellular identity and microbial responsiveness in the intestinal epithelium. 
  • Transcriptional regulation and the evolution of development. 
  • Transcriptional regulation of Bim by FOXO3a and Akt mediates scleroderma serum-induced apoptosis in endothelial progenitor cells. 
  • Transcriptional regulation of N-acetylglutamate synthase. 
  • Transcriptional regulation of Src homology 2 domain-containing leukocyte phosphoprotein of 76 kDa: dissection of key promoter elements. 
  • Transcriptional regulation of matrix gla protein. 
  • Transcriptional regulation of survivin by c-Myc in BCR/ABL-transformed cells: implications in anti-leukaemic strategy. 
  • Transcriptional regulation of the cholesteryl ester transfer protein gene by the orphan nuclear hormone receptor apolipoprotein AI regulatory protein-1. 
  • Transcriptional regulation of the human T cell receptor delta gene. 
  • Transcriptional regulation of the human alpha1a-adrenergic receptor gene. Characterization Of the 5'-regulatory and promoter region. 
  • Transcriptional regulation of the mouse presenilin-1 gene. 
  • Transcriptional regulation of the mouse uncoupling protein-2 gene. Double E-box motif is required for peroxisome proliferator-activated receptor-gamma-dependent activation. 
  • Transcriptional regulation of the tyrosine hydroxylase gene by glucocorticoid and cyclic AMP. 
  • Transcriptional regulator Id2 is required for the CD4 T cell immune response in the development of experimental autoimmune encephalomyelitis. 
  • Transcriptional regulatory functions of heterogeneous nuclear ribonucleoprotein-U and -A/B in endotoxin-mediated macrophage expression of osteopontin. 
  • Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease. 
  • Transcriptional repressor functions of Drosophila E2F1 and E2F2 cooperate to inhibit genomic DNA synthesis in ovarian follicle cells. 
  • Transcriptional response to hypoxia in human tumors. 
  • Transcriptional switches direct plant organ formation and patterning. 
  • Transcriptionally abundant major histocompatibility complex class I alleles are fundamental to nonhuman primate simian immunodeficiency virus-specific CD8+ T cell responses. 
  • Transcriptome analysis of mouse stem cells and early embryos. 
  • Transcriptome profiling of genes involved in neural tube closure during human embryonic development using long serial analysis of gene expression (long-SAGE). 
  • Transforming growth factor β-mediated suppression of antitumor T cells requires FoxP1 transcription factor expression. 
  • Transient expression of a winged-helix protein, MNF-beta, during myogenesis. 
  • Translating Alzheimer's disease-associated polymorphisms into functional candidates: a survey of IGAP genes and SNPs. 
  • Triiodothyronine (T3) decreases binding to DNA by T3-receptor homodimers but not receptor-auxiliary protein heterodimers. 
  • Triiodothyronine (T3) differentially affects T3-receptor/retinoic acid receptor and T3-receptor/retinoid X receptor heterodimer binding to DNA. 
  • Tristetraprolin (TTP) coordinately regulates primary and secondary cellular responses to proinflammatory stimuli. 
  • Tumor necrosis factor induces neuroendocrine differentiation in small cell lung cancer cell lines. 
  • Tumor suppressor MMAC/PTEN inhibits cytokine-induced NFkappaB activation without interfering with the IkappaB degradation pathway. 
  • Two distinct forms of soluble MHC class I molecules synthesized by different mechanisms in normal rat cells in vitro. 
  • Two distinct mechanisms of Topoisomerase 1-dependent mutagenesis in yeast. 
  • Two distinct pathways for cAMP-mediated down-regulation of the beta 2-adrenergic receptor. Phosphorylation of the receptor and regulation of its mRNA level. 
  • Two proteins of gene A of psiX174. 
  • Two steps in Maf1-dependent repression of transcription by RNA polymerase III. 
  • Type 1 neurofibromatosis gene: identification of a large transcript disrupted in three NF1 patients. 
  • Tyrosine hydroxylase transcription depends primarily on cAMP response element activity, regardless of the type of inducing stimulus. 
  • U1-snRNP-A protein selects a ten nucleotide consensus sequence from a degenerate RNA pool presented in various structural contexts. 
  • UV radiation is a transcriptional inducer of p21(Cip1/Waf1) cyclin-kinase inhibitor in a p53-independent manner. 
  • Uncoupling of genomic and epigenetic signals in the maintenance and inheritance of heterochromatin domains in fission yeast. 
  • Uncovering Gene Regulatory Networks Controlling Plant Cell Differentiation. 
  • Update in podocyte biology: putting one's best foot forward. 
  • Use of a specific probe for ovalbumin messenger RNA to quantitate estrogen-induced gene transcripts. 
  • Use of immuno-LCM to identify the in situ expression profile of cellular constituents of the tumor microenvironment. 
  • Use of phage display to identify novel mineralocorticoid receptor-interacting proteins. 
  • Vaccinia virus directs the synthesis of early mRNAs containing 5' poly(A) sequences. 
  • Variation in DNA-Damage Responses to an Inhalational Carcinogen (1,3-Butadiene) in Relation to Strain-Specific Differences in Chromatin Accessibility and Gene Transcription Profiles in C57BL/6J and CAST/EiJ Mice. 
  • Vesicular Trafficking Systems Impact TORC1-Controlled Transcriptional Programs in Saccharomyces cerevisiae. 
  • Vesicular stomatitis virus defective interfering particle containing a muted internal leader RNA gene. 
  • Viral transcription is necessary and sufficient for vesicular stomatitis virus to inhibit maturation of small nuclear ribonucleoproteins. 
  • Vitamin D receptor interaction with specific DNA requires a nuclear protein and 1,25-dihydroxyvitamin D3. 
  • Vitamin D receptors repress basal transcription and exert dominant negative activity on triiodothyronine-mediated transcriptional activity. 
  • Whole-Genome and Transcriptional Analysis of Treatment-Emergent Small-Cell Neuroendocrine Prostate Cancer Demonstrates Intraclass Heterogeneity. 
  • X-chromosome hyperactivation in mammals via nonlinear relationships between chromatin states and transcription. 
  • Yeast RPO41 gene product is required for transcription and maintenance of the mitochondrial genome. 
  • Yin Yang 1 Promotes Thymocyte Survival by Downregulating p53. 
  • Zebrafish as a model for apolipoprotein biology: comprehensive expression analysis and a role for ApoA-IV in regulating food intake. 
  • Zfp423 Maintains White Adipocyte Identity through Suppression of the Beige Cell Thermogenic Gene Program. 
  • [Design, synthesis and evaluation of novel 2H-1, 4-benzodiazepine-2-ones as inhibitors of HIV-1 transcription]. 
  • beta-Arrestin 2 expression determines the transcriptional response to lysophosphatidic acid stimulation in murine embryo fibroblasts. 
  • beta-Arrestin scaffolding of the ERK cascade enhances cytosolic ERK activity but inhibits ERK-mediated transcription following angiotensin AT1a receptor stimulation. 
  • beta-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins. 
  • c-Jun Contributes to Transcriptional Control of GNA12 Expression in Prostate Cancer Cells. 
  • c-Jun enhancement of cyclic adenosine 3',5'-monophosphate response element-dependent transcription induced by transforming growth factor-beta is independent of c-Jun binding to DNA. 
  • c-Myc Represses Transcription of Epstein-Barr Virus Latent Membrane Protein 1 Early after Primary B Cell Infection. 
  • c-Myc creates an activation loop by transcriptionally repressing its own functional inhibitor, hMad4, in young fibroblasts, a loop lost in replicatively senescent fibroblasts. 
  • c-Myc represses FOXO3a-mediated transcription of the gene encoding the p27(Kip1) cyclin dependent kinase inhibitor. 
  • cAMP stimulates transcription of the beta 2-adrenergic receptor gene in response to short-term agonist exposure. 
  • cDNA cloning of the type 1 neurofibromatosis gene: complete sequence of the NF1 gene product. 
  • dUTP incorporation into genomic DNA is linked to transcription in yeast. 
  • hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization. 
  • mRNA Metabolism in Cardiac Development and Disease: Life After Transcription. 
  • mRNAs coding for proteins of the cGMP cascade in the degenerative retina of the rd mouse. 
  • mTOR coordinates transcriptional programs and mitochondrial metabolism of activated Treg subsets to protect tissue homeostasis. 
  • n-Butyrate, a cell cycle blocker, inhibits early amplification of duck hepatitis B virus covalently closed circular DNA after in vitro infection of duck hepatocytes. 
  • optix Drives the Repeated Convergent Evolution of Butterfly Wing Pattern Mimicry 
  • p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene. 
  • p53 does not repress hypoxia-induced transcription of the vascular endothelial growth factor gene. 
  • p62, A TFIIH subunit, directly interacts with thyroid hormone receptor and enhances T3-mediated transcription. 
  • uORF-mediated translation allows engineered plant disease resistance without fitness costs. 
  • ¹H, ¹³C and ¹⁵N backbone and side-chain resonance assignments of Drosophila melanogaster Ssu72. 
  • β-arrestin1 mediates metastatic growth of breast cancer cells by facilitating HIF-1-dependent VEGF expression. 
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  Keywords of People

  • Bejsovec, Amy, Associate Professor of Biology, Biology
  • Bennett, Vann, George Barth Geller Distinguished Professor of Molecular Biology, Duke Cancer Institute
  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Ciofani, Maria, Associate Professor of Integrative Immunobiology, Cell Biology
  • Ferrari, Guido, Professor in Surgery, Molecular Genetics and Microbiology
  • Hartemink, Alexander J., Professor in the Department of Computer Science, Biology
  • Hirschey, Matthew, Associate Professor of Medicine, Cell Biology
  • Hogan, Brigid L. M., Research Professor of Cell Biology, Cell Biology
  • Krangel, Michael S., George Barth Geller Distinguished Professor of Immunology, Integrative Immunobiology
  • Linardic, Corinne Mary, Associate Professor of Pediatrics, Cell Biology
  • McDonnell, Donald Patrick, Glaxo-Wellcome Distinguished Professor of Molecular Cancer Biology, in the School of Medicine, Cell Biology
  • McLendon, Roger Edwin, Professor of Pathology, Pathology
  • Reddy, Timothy E, Associate Professor of Biostatistics & Bioinformatics,, Molecular Genetics and Microbiology
  • Schmid, Amy K., David M. Goodner Associate Professor, Duke Science & Society
  • Shinohara, Mari L., Professor of Integrative Immunobiology, Cell Biology
  • Weinhold, Kent James, Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery, Integrative Immunobiology
  • Wray, Gregory Allan, Professor of Biology, Evolutionary Anthropology
  • Zhong, Xiaoping, Professor of Pediatrics, Integrative Immunobiology