Transferrin

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  Subject Areas on Research

  • A mutation in Sec15l1 causes anemia in hemoglobin deficit (hbd) mice. 
  • A novel murine protein with no effect on iron homoeostasis is homologous with transferrin and is the putative inhibitor of carbonic anhydrase. 
  • Altered proteolytic activities of ADAMTS-4 expressed by C-terminal processing. 
  • Antibodies to endometrial transferrin and alpha 2-Heremans Schmidt (HS) glycoprotein in patients with endometriosis. 
  • Apical and basolateral endocytic pathways of MDCK cells meet in acidic common endosomes distinct from a nearly-neutral apical recycling endosome. 
  • Balancing acts: molecular control of mammalian iron metabolism. 
  • Brefeldin A rapidly disrupts plasma membrane polarity by blocking polar sorting in common endosomes of MDCK cells. 
  • Cloning, sequencing, and recombinant expression of the porcine inhibitor of carbonic anhydrase: a novel member of the transferrin family. 
  • Comparison of the interactions of transferrin receptor and transferrin receptor 2 with transferrin and the hereditary hemochromatosis protein HFE. 
  • Copper-stimulated endocytosis and degradation of the human copper transporter, hCtr1. 
  • DMT1 expression is increased in the lungs of hypotransferrinemic mice. 
  • Deficiency of α-1-antitrypsin influences systemic iron homeostasis. 
  • Definition of distinct compartments in polarized Madin-Darby canine kidney (MDCK) cells for membrane-volume sorting, polarized sorting and apical recycling. 
  • Distribution of transferrin saturations in the African-American population. 
  • Effect of Oral Iron Repletion on Exercise Capacity in Patients With Heart Failure With Reduced Ejection Fraction and Iron Deficiency: The IRONOUT HF Randomized Clinical Trial. 
  • Effect of iron deficiency on tissue oxygen delivery in cyanotic congenital heart disease. 
  • Enhanced mobilization of iron from body stores in malnourished patients during intravenous nutritional support. 
  • Enhancement of the activity of cefotaxime by iron-binding proteins. 
  • Evidence for a low Km transporter for non-transferrin-bound iron in isolated rat hepatocytes. 
  • Evidence of Fe3+ interaction with the plug domain of the outer membrane transferrin receptor protein of Neisseria gonorrhoeae: implications for Fe transport. 
  • Expression of EGF receptor and transferrin by F9 and PC13 teratocarcinoma cells. 
  • Expression of the DMT1 (NRAMP2/DCT1) iron transporter in mice with genetic iron overload disorders. 
  • Fe3+ coordination and redox properties of a bacterial transferrin. 
  • Hfe deficiency increases susceptibility to cardiotoxicity and exacerbates changes in iron metabolism induced by doxorubicin. 
  • Hijacking transferrin bound iron: protein-receptor interactions involved in iron transport in N. gonorrhoeae. 
  • Identification of the segments of the mouse transferrin receptor 1 required for mouse mammary tumor virus infection. 
  • Identifying responders to oral iron supplementation in heart failure with a reduced ejection fraction: a post-hoc analysis of the IRONOUT-HF trial. 
  • Improving sensitivity and specificity of capturing and detecting targeted cancer cells with anti-biofouling polymer coated magnetic iron oxide nanoparticles. 
  • In vitro preparation of nonenzymatically glucosylated human transferrin, alpha 2-macroglobulin, and fibrinogen with preservation of function. 
  • Iron deficiency anemia: its relationship to infection susceptibility and host defense. 
  • Iron deficiency in young Lebanese children: association with elevated blood lead levels. 
  • Iron homeostasis and oxidative stress in idiopathic pulmonary alveolar proteinosis: a case-control study. 
  • Iron importers Zip8 and Zip14 are expressed in retina and regulated by retinal iron levels. 
  • Iron increases expression of iron-export protein MTP1 in lung cells. 
  • Iron metabolism: iron deficiency and iron overload. 
  • Iron overload following red blood cell transfusion and its impact on disease severity. 
  • Kinetics and mechanism of iron release from the bacterial ferric binding protein nFbp: exogenous anion influence and comparison with mammalian transferrin. 
  • Kinetics of iron release from ferric binding protein (FbpA): mechanistic implications in bacterial periplasm-to-cytosol Fe3+ transport. 
  • Levels of transferrin and alpha 2-HS glycoprotein in women with and without endometriosis. 
  • Lung injury after ozone exposure is iron dependent. 
  • Massive pleural transudate following a vertebral fusion in a 49-year-old woman. 
  • Metabolic capacity regulates iron homeostasis in endothelial cells. 
  • Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport. 
  • Oxygen toxicity and iron accumulation in the lungs of mice lacking heme oxygenase-2. 
  • Phosphate ester hydrolysis is catalyzed by a bacterial transferrin: potential implications for in vivo iron transport mechanisms. 
  • Phosphoinositide 3-kinase regulates beta2-adrenergic receptor endocytosis by AP-2 recruitment to the receptor/beta-arrestin complex. 
  • Plasma proteins as indices of response to nutritional therapy in cancer patients. 
  • Prevalence of heterozygotes for hemochromatosis in the white population of the United States. 
  • Protein kinase activity of phosphoinositide 3-kinase regulates beta-adrenergic receptor endocytosis. 
  • Real-Time Transferrin-Based PET Detects MYC-Positive Prostate Cancer. 
  • Receptors on hepatocytes that bind ligands containing fucosyl alpha 1,3 N-acetylglucosamine linkages. 
  • Redox properties of human transferrin bound to its receptor. 
  • Regulation of Sertoli cell differentiation by the testicular paracrine factor PModS: potential role of immediate-early genes. 
  • Regulation of Sertoli cell function and differentiation through the actions of a testicular paracrine factor P-Mod-S. 
  • Regulation of iron absorption in Hfe mutant mice. 
  • Relationship between transferrin saturation and iron stores in the African American and US Caucasian populations: analysis of data from the third National Health and Nutrition Examination Survey. 
  • STRUCTURE AND FUNCTION OF IRON-FLAVOPROTEINS. 
  • Scara5 is a ferritin receptor mediating non-transferrin iron delivery. 
  • Simultaneous and completely automated methods for serum iron and iron-binding capacity determinations. 
  • Sulfate as a synergistic anion facilitating iron binding by the bacterial transferrin FbpA: the origins and effects of anion promiscuity. 
  • Targeted drug delivery to C6 glioma by transferrin-coupled liposomes. 
  • The antiproliferative effect of a transferrin-toxin on human retinal pigment epithelial cells and rabbit fibroblasts. 
  • The binding of fucose-containing glycoproteins by hepatic lectins. Re-examination of the clearance from blood and the binding to membrane receptors and pure lectins. 
  • The clearance of human fibrinogen fragments D1, D2, D3 and fibrin fragment D1 dimer in mice. 
  • The influence of the synergistic anion on iron chelation by ferric binding protein, a bacterial transferrin. 
  • The measurement of free erythrocyte porphyrin (FEP) as a simple means of distinguishing iron deficiency from beta-thalassemia trait in subjects with microcytosis. 
  • The molecular defect in hypotransferrinemic mice. 
  • The molecular regulation of iron metabolism. 
  • The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression. 
  • Transferrin increases adherence of iron-deprived Neisseria gonorrhoeae to human endometrial cells. 
  • Transferrin is a major determinant of hepcidin expression in hypotransferrinemic mice. 
  • Transferrin is required for early T-cell differentiation. 
  • Transferrin receptor is necessary for development of erythrocytes and the nervous system. 
  • Transferrin-ricin A chain toxin limits the development of experimental proliferative vitreoretinopathy. 
  • Unusual Synergism of Transferrin and Citrate in the Regulation of Ti(IV) Speciation, Transport, and Toxicity. 
  • Use of beta-2-transferrin to diagnose CSF leakage following spinal surgery: a case report. 
  • Vascular release of nonheme iron in perfused rabbit lungs. 
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  Keywords of People

  • Turi, Jennifer Lilly, Associate Professor of Pediatrics, Pediatrics, Critical Care Medicine