Transplantation, Autologous

• 

  Subject Areas on Research

  • "Short course" bortezomib plus melphalan and prednisone as induction prior to transplant or as frontline therapy for nontransplant candidates in patients with previously untreated multiple myeloma. 
  • 4-hydroperoxycyclophosphamide--purged peripheral blood stem cells for autologous transplantation in patients with acute myeloid leukemia. 
  • A Biomechanical Evaluation of Auricular Cartilage Autografts in Orbital Floor Defect Repair. 
  • A Phase I study of active immunotherapy with carcinoembryonic antigen peptide (CAP-1)-pulsed, autologous human cultured dendritic cells in patients with metastatic malignancies expressing carcinoembryonic antigen. 
  • A biomechanical study of human lateral ankle ligaments and autogenous reconstructive grafts. 
  • A feasibility study of multiple cycle therapy with melphalan, thiotepa, and paclitaxel followed by mitoxantrone, thiotepa, and paclitaxel with autologous hematopoietic cell support for metastatic breast cancer. 
  • A functional tethered ligand thrombin receptor is present on human hematopoietic progenitor cells. 
  • A new preparatory regimen for autologous bone marrow transplantation for patients with lymphoma. 
  • A phase 1/2 study of an adjuvanted varicella-zoster virus subunit vaccine in autologous hematopoietic cell transplant recipients. 
  • A phase 3, randomized, double-blinded, active-controlled, unblinded standard of care study assessing the efficacy and safety of intramyocardial autologous CD34+ cell administration in patients with refractory angina: design of the RENEW study. 
  • A phase I trial of recombinant human interleukin-1 beta (OCT-43) following high-dose chemotherapy and autologous bone marrow transplantation. 
  • A phase I/II study of CY and topotecan in patients with high-risk malignancies undergoing autologous hematopoietic cell transplantation: the St Jude long-term follow-up. 
  • A predictive model for relapse in high-risk primary breast cancer patients treated with high-dose chemotherapy and autologous stem-cell transplant. 
  • A radiologic syndrome after high dose chemotherapy and autologous bone marrow transplantation, with clinical and pathologic features of systemic candidiasis. 
  • A randomized phase III comparative trial of immediate consolidation with high-dose chemotherapy and autologous peripheral blood progenitor cell support compared to observation with delayed consolidation in women with metastatic breast cancer and only bone metastases following intensive induction chemotherapy. 
  • A randomized study of erythropoietin and granulocyte colony-stimulating factor (G-CSF) versus placebo and G-CSF for patients with Hodgkin's and non-Hodgkin's lymphoma undergoing autologous bone marrow transplantation. 
  • A randomized trial of recombinant human interleukin-11 following autologous bone marrow transplantation with peripheral blood progenitor cell support in patients with breast cancer. 
  • Aerosol transfer of bladder urothelial and smooth muscle cells onto demucosalized colonic segments for bladder augmentation: in vivo, long term, and functional pilot study. 
  • Allograft anterior cruciate ligament reconstruction in a sheep model. The effect of synthetic augmentation. 
  • Alterations in L-selectin expression and elastase activity in neutrophils from patients receiving granulocyte colony-stimulating factor alone or in conjunction with high-dose chemotherapy with autologous bone marrow transplantation. 
  • Alveolar rhabdomyosarcoma that metastasized to the orbit. 
  • Amendment to Clinical Research Project. Project 90-C-195. April 1, 1993. Treatment of severe combined immunodeficiency disease (SCID) due to adenosine deaminase deficiency with autologous lymphocytes transduced with a human ADA gene. 
  • An adherence tensiometer for evaluation of burn dressings. 
  • Analysis of failures after vascularized fibular grafting in femoral head necrosis. 
  • Auto-SCT for AML in second remission: CALGB study 9620. 
  • Autologous and allogeneic transplantation for burkitt lymphoma outcomes and changes in utilization: a report from the center for international blood and marrow transplant research. 
  • Autologous bone marrow transplantation in acute myelogenous leukemia: in vitro treatment with myeloid-specific monoclonal antibodies and drugs in combination. 
  • Autologous cortical bone grafts with microsurgical anastomosis of periosteal vessels. 
  • Autologous dendritic cells transfected with prostate-specific antigen RNA stimulate CTL responses against metastatic prostate tumors. 
  • Autologous or reduced-intensity conditioning allogeneic hematopoietic cell transplantation for chemotherapy-sensitive mantle-cell lymphoma: analysis of transplantation timing and modality. 
  • Autologous stem cell transplantation for autoimmune diseases: issues in protocol development. 
  • Autologous transplantation of CD133 selected hematopoietic progenitor cells for treatment of relapsed acute lymphoblastic leukemia. 
  • Autologous tumor rejection in humans: trimming the myths. 
  • Avascular necrosis of the talus: current treatment options. 
  • Behavior of sutures used in anterior cruciate ligament reconstructive surgery. 
  • Biologic activity of irradiated, autologous, GM-CSF-secreting leukemia cell vaccines early after allogeneic stem cell transplantation. 
  • Bone marrow transplantation for hematologic malignancies: the Stanford experience. 
  • Bone marrow transplantation. Part II--autologous. 
  • Bone-grafting in total hip replacement for acetabular protrusion. 
  • Brachial artery reconstruction using the heparin-bonded Sundt shunt. 
  • Busulfan/etoposide--initial experience with a new preparatory regimen for autologous bone marrow transplantation in patients with acute nonlymphoblastic leukemia. 
  • Can We Cure Light Chain Deposition Disease of the Kidneys?-A Review and Case Report of a Patient Treated With a Triple Transplant Approach. 
  • Can underpowered clinical trials be justified? 
  • Clinical utility of computed tomography screening of chest, abdomen, and sinuses before hematopoietic stem cell transplantation: the St. Jude experience. 
  • Coagulation and fibrinolytic protein kinetics in cardiopulmonary bypass. 
  • Comparative effects of granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) on priming peripheral blood progenitor cells for use with autologous bone marrow after high-dose chemotherapy. 
  • Comparison of benefits on myocardial performance of cellular cardiomyoplasty with skeletal myoblasts and fibroblasts. 
  • Comparison of ¹²³I-metaiodobenzylguanidine (MIBG) and ¹³¹I-MIBG semi-quantitative scores in predicting survival in patients with stage 4 neuroblastoma: a report from the Children's Oncology Group. 
  • Complete and incomplete revascularization at aortocoronary bypass surgery: experience with 392 consecutive patients. 
  • Complex abdominal wall hernias: a new classification system and approach to management based on review of 133 consecutive patients. 
  • Corticosteroid therapy for diffuse alveolar hemorrhage in autologous bone marrow transplant recipients. 
  • Delayed autotransplantation of a solitary kidney facilitated by pump perfusion preservation. 
  • Delivery of primary autologous skeletal myoblasts into rabbit heart by coronary infusion: a potential approach to myocardial repair. 
  • Diagnostic challenge in recurrent skin rash after autologous bone marrow transplantation. 
  • Disabling immune tolerance by programmed death-1 blockade with pidilizumab after autologous hematopoietic stem-cell transplantation for diffuse large B-cell lymphoma: results of an international phase II trial. 
  • Disseminated intravascular coagulation and renal failure: Production in the monkey with autologous red blood cell stroma. 
  • Dynamic assessment of quality of life after autologous bone marrow transplantation. 
  • Early failure of frontline rituximab-containing chemo-immunotherapy in diffuse large B cell lymphoma does not predict futility of autologous hematopoietic cell transplantation. 
  • Effects of granulocyte-macrophage colony stimulating factor produced in Chinese hamster ovary cells (regramostim), Escherichia coli (molgramostim) and yeast (sargramostim) on priming peripheral blood progenitor cells for use with autologous bone marrow after high-dose chemotherapy. 
  • Effects of leukocyte depleted blood on renal reperfusion injury in a porcine model. 
  • Efficacy and safety of edifoligide, an E2F transcription factor decoy, for prevention of vein graft failure following coronary artery bypass graft surgery: PREVENT IV: a randomized controlled trial. 
  • Efficacy and safety of hematopoietic stem cell remobilization with plerixafor+G-CSF in adult patients with germ cell tumors. 
  • Endolymphatic immunotherapy in inoperable hepatocellular carcinoma. 
  • Engraftment in 86 with patients lymphoid malignancy after autologous marrow transplantation. 
  • Enrichment of peripheral blood stem cells in a primate model following administration of a single dose of rh-IL-1 beta. 
  • Epstein-Barr virus-associated lymphoproliferative disorder following autologous bone marrow transplantation for non-Hodgkin's lymphoma. 
  • Ethical issues in umbilical cord blood banking. Working Group on Ethical Issues in Umbilical Cord Blood Banking. 
  • Etoposide, cyclophosphamide and fractionated total body irradiation as a preparative regimen for marrow transplantation in patients with advanced hematological malignancies: a phase I study. 
  • Evaluation of the spectra Optia® mononuclear cell collection procedure in multiple myeloma patients. 
  • Exercise echocardiographic comparison of pulmonary autograft and aortic homograft replacements for aortic valve disease in adults. 
  • Experimental cryopreservation and autotransplantation of parathyroid glands: technique and demonstration of function. 
  • Factors associated with infection following anterior cruciate ligament reconstruction. 
  • Factors associated with insulin and narcotic independence after islet autotransplantation in patients with severe chronic pancreatitis. 
  • Family-directed umbilical cord blood banking. 
  • Feasibility of autologous cord blood cells for infants with hypoxic-ischemic encephalopathy. 
  • Feasibility of frequent patient-reported outcome surveillance in patients undergoing hematopoietic cell transplantation. 
  • Four-cycle high-dose therapy with hematopoietic support for metastatic breast cancer: no improvement in outcomes compared with single-course high-dose therapy. 
  • Free vascularized fibular graft reconstruction of large skeletal defects after tumor resection. 
  • Free vascularized fibular grafting preserves athletic activity level in patients with osteonecrosis. 
  • Frequent detection of tumor cells in hematopoietic grafts in neuroblastoma and Ewing's sarcoma. 
  • Functional abnormalities of experimental autogenous vein graft neoendothelium. 
  • Gait abnormalities and inflammatory cytokines in an autologous nucleus pulposus model of radiculopathy. 
  • Generation of autologous tumor-specific cytotoxic T-cells using HLA-A region matched allogeneic melanoma. 
  • Graft-bone healing of a meniscus autograft anchored in bone tunnels. 
  • Hematopoietic cell transplant comorbidity index is predictive of survival after autologous hematopoietic cell transplantation in multiple myeloma. 
  • Hematopoietic recovery following high-dose combined alkylating-agent chemotherapy and autologous bone marrow support in patients in phase-I clinical trials of colony-stimulating factors: G-CSF, GM-CSF, IL-1, IL-2, M-CSF. 
  • High-dose alkylating agent chemotherapy with autologous bone marrow support in patients with stage III/IV epithelial ovarian cancer. 
  • High-dose chemotherapy and autologous bone marrow support as consolidation after standard-dose adjuvant therapy for high-risk primary breast cancer. 
  • High-dose chemotherapy with autologous stem-cell rescue in children and adults with newly diagnosed pineoblastomas. 
  • High-dose chemotherapy with autologous stem-cell rescue in patients with recurrent and high-risk pediatric brain tumors. 
  • High-dose combination alkylating agents with bone marrow support as initial treatment for metastatic breast cancer. 
  • High-dose combination cyclophosphamide, cisplatin, and melphalan with autologous bone marrow support. A clinical and pharmacologic study. 
  • High-dose immunosuppressive therapy for severe systemic sclerosis: initial outcomes. 
  • High-dose therapy and autologous bone marrow transplantation for follicular lymphoma in first complete or partial remission: results of a phase II clinical trial. 
  • High-dose therapy and autologous hematopoietic progenitor cell transplantation for recurrent or refractory Hodgkin's disease: analysis of the Stanford University results and prognostic indices. 
  • Hypertension and reversible myocardial depression associated with autologous bone marrow transplantation. 
  • Immunopharmacologic purging of breast cancer from bone marrow for autologous bone marrow transplantation. 
  • Immunotherapy with autologous, human dendritic cells transfected with carcinoembryonic antigen mRNA. 
  • Impact of pre-transplant depression on outcomes of allogeneic and autologous hematopoietic stem cell transplantation. 
  • Improved quality of life following total pancreatectomy and auto-islet transplantation for chronic pancreatitis. 
  • Incidence and clinical significance of cardiac biomarker elevation during stem cell mobilization, apheresis, and intramyocardial delivery: an analysis from ACT34-CMI. 
  • Increased yield of endothelial cells from peripheral blood for cell therapies and tissue engineering. 
  • Induced corneal astigmatism after macular translocation surgery with scleral infolding. 
  • Influence of preparatory regimen and source of hematopoietic cells on outcome of autotransplantation for non-Hodgkin's lymphoma. 
  • Inhaled steroids as prophylaxis for delayed pulmonary toxicity syndrome in breast cancer patients undergoing high-dose chemotherapy and autologous stem cell transplantation. 
  • Inhibition of vessel allograft rejection by endothelial removal. Morphologic and ultrastructural changes. 
  • Intracardiac transplantation of skeletal myoblasts yields two populations of striated cells in situ. 
  • Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial. 
  • Intramyocardial, autologous CD34+ cell therapy for refractory angina. 
  • Isolation and transplantation of autologous circulating endothelial cells into denuded vessels and prosthetic grafts: implications for cell-based vascular therapy. 
  • LDH isoenzymes and myocardial infarction in patients undergoing coronary bypass surgery: an excellent correlation. 
  • Laceration of the flexor pollicis longus tendon: delayed repair by advancement, free graft or direct suture. A clinical and experimental study. 
  • Laparoscopic intracorporeal harvest of jejunal tissue for autologous transplantation. 
  • Late complications of allogeneic and autologous marrow transplantation. 
  • Long-term evaluation of patients with primary parathyroid hyperplasia managed by total parathyroidectomy and heterotopic autotransplantation. 
  • Long-term follow-up of patients who received recombinant human granulocyte-macrophage colony stimulating factor after autologous bone marrow transplantation for lymphoid malignancy. 
  • Magnetic Resonance Imaging Characterization and Clinical Outcomes After NeoCart Surgical Therapy as a Primary Reparative Treatment for Knee Cartilage Injuries. 
  • Management of bone in digital replantation: free vascularized and composite bone grafts. 
  • Management of recurrent melanoma of the extremity. 
  • Marrow transplantation for malignant plasma cell disorders: summary of the Seattle experience. 
  • Metacarpal reconstruction with free autogenous cartilage and bone following tumor resection. A case report. 
  • Microvascular management of ring avulsion injuries. 
  • Mobilization, collection, and processing of autologous peripheral blood stem cells: development of a clinical process with associated costs. 
  • Monkey median nerve repaired by nerve graft or collagen nerve guide tube. 
  • Neuromuscular and biomechanical landing performance subsequent to ipsilateral semitendinosus and gracilis autograft anterior cruciate ligament reconstruction. 
  • Neutrophil migration is defective during recombinant human granulocyte-macrophage colony-stimulating factor infusion after autologous bone marrow transplantation in humans. 
  • Noninvasive assessment of the effects of aorta-coronary bypass grafting on ventricular function during rest and exercise. 
  • Older patients with myeloma derive similar benefit from autologous transplantation. 
  • Optimal timing of autologous cranioplasty after decompressive craniectomy in children. 
  • Osteochondral autologous transfer system. 
  • Osteochondral lesions: medial versus lateral, persistent pain, cartilage restoration options and indications. 
  • Outcome after autogenous brachial-basilic upper arm transpositions in the post-National Kidney Foundation Dialysis Outcomes Quality Initiative era. 
  • Parathyroid autotransplantation: use of cryopreserved glands in an investigation of hypocalcemia. 
  • Pattern formation on lepidopteran wings: determination of an eyespot. 
  • Pediatric femoral avascular necrosis after pyarthrosis: use of free vascularized fibular grafting. 
  • Peripheral nerve regeneration: an opinion on channels, scaffolds and anisotropy. 
  • Persistence and survival of autologous muscle derived cells versus bovine collagen as potential treatment of stress urinary incontinence. 
  • Popliteal artery aneurysms. Past and present. 
  • Post-mastectomy radiotherapy following adjuvant chemotherapy and autologous bone marrow transplantation for breast cancer patients with greater than or equal to 10 positive axillary lymph nodes. Cancer and Leukemia Group B. 
  • Postoperative function of "free" jejunal transplants for replacement of the cervical esophagus. 
  • Preoperative assessment of left ventricular function in patients selected for direct myocardial revascularization. 
  • Preparation techniques for the injection of human autologous cartilage: an ex vivo feasibility study. 
  • Prospective economic evaluation accompanying a trial of GM-CSF/IL-3 in patients undergoing autologous bone marrow transplantation for Hodgkin's and non-Hodgkin's lymphoma. IL-3 BMT Study Team. 
  • Pubovaginal sling using cadaveric allograft fascia for the treatment of intrinsic sphincter deficiency. 
  • Pulmonary toxicity of induction chemotherapy prior to standard or high-dose chemotherapy with autologous hematopoietic support. 
  • Quality of life among patients with Stage II and III breast carcinoma randomized to receive high-dose chemotherapy with autologous bone marrow support or intermediate-dose chemotherapy: results from Cancer and Leukemia Group B 9066. 
  • Quantitative measures of physical functioning after autologous hematopoietic stem cell transplantation in multiple myeloma: a feasibility study. 
  • Randomized trial of high-dose chemotherapy with autologous bone marrow support as adjuvant therapy for high-risk, multi-node-positive malignant melanoma. 
  • Reconstruction of the rabbit trachea with vascularized auricular perichondrium. 
  • Reduced-intensity conditioning allogeneic hematopoietic cell transplantation for patients with hematologic malignancies who relapse following autologous transplantation: a multi-institutional prospective study from the Cancer and Leukemia Group B (CALGB trial 100002). 
  • Relationship between provider volume and outcomes for orthotopic liver transplantation. 
  • Renal artery aneurysm in a solitary kidney: successful surgical repair. 
  • Renal autotransplants in sheep: investigation of renal function and renovascular hypertension. 
  • Repeated autologous umbilical cord blood infusions are feasible and had no acute safety issues in young babies with congenital hydrocephalus. 
  • Results with titanium ossicular reconstruction prostheses. 
  • Reticulated platelet counts in patients undergoing autologous bone marrow transplantation: an aid in assessing marrow recovery. 
  • Retinopathy and optic neuropathy in bone marrow transplantation for breast cancer. 
  • Risk factors in coronary artery bypass surgery. 
  • Risk of distal embolization and infarction with transluminal extraction atherectomy in saphenous vein grafts and native coronary arteries. NACI Investigators. New Approaches to Coronary Interventions. 
  • Role of Fresh Osteochondral Allografts for Large Talar Osteochondral Lesions. 
  • Role of cytokines in autologous bone marrow transplantation. 
  • SUCCESSFUL REPAIR OF RECURRENT OPTIC DISK PIT MACULOPATHY WITH AUTOLOGOUS PLATELET RICH PLASMA: REPORT OF A SURGICAL TECHNIQUE. 
  • Salvage of advanced squamous cell carcinomas of the head and neck: internal carotid artery sacrifice and extracranial-intracranial revascularization. 
  • Secondary failure of platelet recovery after hematopoietic stem cell transplantation. 
  • Secondary myelodysplasia and acute leukemia in breast cancer patients after autologous bone marrow transplant. 
  • Selection of patients for heterotopic implantation of the areola and nipple. 
  • Semiautologous repair for congenital discontinuous right pulmonary artery. 
  • Sequential high-dose ifosfamide, carboplatin and etoposide with rituximab for relapsed Hodgkin and large B-cell non-Hodgkin lymphoma: increased toxicity without improvement in progression-free survival. 
  • Sequential myeloablative autologous stem cell transplantation and reduced intensity allogeneic hematopoietic cell transplantation is safe and feasible in children, adolescents and young adults with poor-risk refractory or recurrent Hodgkin and non-Hodgkin lymphoma. 
  • Spermine dialdehyde, a novel ex vivo purging agent for both allogenic and autologous bone marrow transplantations. 
  • Spinal bone density following spinal fusion. 
  • Stem cell transplantation for multiple myeloma. 
  • Subtalar distraction arthrodesis using interpositional frozen structural allograft. 
  • Systolic contraction within aneurysmal rabbit myocardium following transplantation of autologous skeletal myoblasts. 
  • T lymphocytes with a normal ADA gene accumulate after transplantation of transduced autologous umbilical cord blood CD34+ cells in ADA-deficient SCID neonates. 
  • Technology evaluation: Stem-cell therapy, Aastrom Biosciences Inc. 
  • The Athena trials: Autologous adipose-derived regenerative cells for refractory chronic myocardial ischemia with left ventricular dysfunction. 
  • The Ross procedure: shorter hospital stay, decreased morbidity, and cost effective. 
  • The Stanford experience with high-dose etoposide cytoreductive regimens and autologous bone marrow transplantation in Hodgkin's disease and non-Hodgkin's lymphoma: preliminary data. 
  • The morbidity associated with osteochondral harvest from asymptomatic knees for the treatment of osteochondral lesions of the talus. 
  • The use of autologous adult, allogenic juvenile, and combined juvenile-adult cartilage fragments for the repair of chondral defects. 
  • The use of recombinant human granulocyte-macrophage colony-stimulating factor in autologous bone marrow transplantation. 
  • The viability of cells obtained using the Reamer-Irrigator-Aspirator system and in bone graft from the iliac crest. 
  • Tibial nerve grafting for restoration of plantar sensation. 
  • Tissue-engineered scaffolds are effective alternatives to autografts for bridging peripheral nerve gaps. 
  • Tissue-engineered vascular grafts: autologous off-the-shelf vascular access? 
  • Total pancreatectomy and autologous islet cell transplantation as a means to treat severe chronic pancreatitis. 
  • Toxicity, pharmacology and feasibility of administration of PEG-L-asparaginase as consolidation therapy in patients undergoing bone marrow transplantation for acute lymphoblastic leukemia. 
  • Transplantation for autoimmune diseases in north and South America: a report of the Center for International Blood and Marrow Transplant Research. 
  • Transplantation in miniature swine. 
  • Transplantation of feline islets of Langerhans in the subretinal space of cat eyes. 
  • Transplantation of the parathyroid glands in man: clinical indications and results. 
  • Treatment of osteonecrosis of the femoral head with free vascularized fibular grafting. A long-term follow-up study of one hundred and three hips. 
  • Ulnar artery insufficiency: a guide to treatment. 
  • Umbilical cord blood: a novel alternative source of hematopoietic stem cells for bone marrow transplantation. 
  • Urologic surgery. 
  • Use of autograft quadriceps tendon for double-bundle posterior cruciate ligament reconstruction. 
  • Value of surgical resection in children with high-risk neuroblastoma. 
  • Vascularization and the gliding mechanism of free flexor-tendon grafts inserted by the silicone-rod method. 
  • Vascularized fibula-based physis transfer for pediatric proximal humerus reconstruction. 
  • What do we really know about allografts? 
  • [Assessment of therapeutic results for simple bone cyst with percutaneous injection of autogenous bone marrow]. 
• 

  Keywords of People

  • Alexander, John Hunter Peel, Professor of Medicine, Medicine, Cardiology
  • Attarian, David Edward, Professor of Orthopaedic Surgery, Orthopaedics
  • Barfield, Raymond Carlton, Associate Professor of Pediatrics, Duke Science & Society
  • Berchuck, Andrew, James M. Ingram Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Cohen, Seth Morris, Associate Professor of Surgery, Surgery, Head and Neck Surgery and Communication Sciences
  • Setton, Lori A., Adjunct Professor of Biomedical Engineering, Biomedical Engineering
  • Starmer, Charles Franklin, Professor Emeritus of Computer Science, Computer Science
  • Toth, Cynthia Ann, Joseph A.C. Wadsworth Professor of Ophthalmology, Biomedical Engineering