Triglycerides

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  Subject Areas on Research

  • A LCMS-based untargeted lipidomics analysis of cleft palate in mouse. 
  • A Liver-Specific Thyromimetic, VK2809, Decreases Hepatosteatosis in Glycogen Storage Disease Type Ia. 
  • A Systems Approach Dissociates Fructose-Induced Liver Triglyceride from Hypertriglyceridemia and Hyperinsulinemia in Male Mice. 
  • A comparison of methods for the estimation of plasma low- and very low-density lipoprotein cholesterol. The Lipid Research Clinics Prevalence Study. 
  • A comparison of the effectiveness of lipid-lowering therapy between HIV- and non-HIV-infected subjects with hyperlipidaemia. 
  • A comparison of time dependent Cox regression, pooled logistic regression and cross sectional pooling with simulations and an application to the Framingham Heart Study. 
  • A futile metabolic cycle activated in adipocytes by antidiabetic agents. 
  • A physicochemical study of fat absorption in rats. Limitation of methods in vitro. 
  • A randomized trial examining the effectiveness of switching from olanzapine, quetiapine, or risperidone to aripiprazole to reduce metabolic risk: comparison of antipsychotics for metabolic problems (CAMP). 
  • A review of low-carbohydrate ketogenic diets. 
  • A rodent model of rapid-onset diabetes induced by glucocorticoids and high-fat feeding. 
  • A telephone-delivered intervention for patients with NIDDM. Effect on coronary risk factors. 
  • A text messaging-assisted randomized lifestyle weight loss clinical trial among overweight adults in Beijing. 
  • A very low-carbohydrate, low-saturated fat diet for type 2 diabetes management: a randomized trial. 
  • AMP-activated kinase reciprocally regulates triacylglycerol synthesis and fatty acid oxidation in liver and muscle: evidence that sn-glycerol-3-phosphate acyltransferase is a novel target. 
  • Ablation of calcineurin Aβ reveals hyperlipidemia and signaling cross-talks with phosphodiesterases. 
  • Abnormalities of carbohydrate and lipid metabolism in Dahl rats. 
  • Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease. 
  • Accurate fatty acid composition estimation of adipose tissue in the abdomen based on bipolar multi-echo MRI. 
  • Achievement of recommended lipid and lipoprotein levels with combined ezetimibe/statin therapy versus statin alone in patients with and without diabetes. 
  • Activation of direct and indirect pathways of glycogen synthesis by hepatic overexpression of protein targeting to glycogen. 
  • Acute changes in serum lipids and lipoprotein subclasses in triathletes as assessed by proton nuclear magnetic resonance spectroscopy. 
  • Acyl-CoAs are functionally channeled in liver: potential role of acyl-CoA synthetase. 
  • Adaptation to fat markedly increases pancreatic secretory response to intraduodenal fat in rats. 
  • Adenomas induced by polycyclic aromatic hydrocarbons in strain A/J mouse lung correlate with time-integrated DNA adduct levels. 
  • Adenovirus-mediated overexpression of uncoupling protein-2 in pancreatic islets of Zucker diabetic rats increases oxidative activity and improves beta-cell function. 
  • Adiposity, cardiometabolic risk, and vitamin D status: the Framingham Heart Study. 
  • Adrenergic effects on plasma lipoprotein metabolism. Speculation on mechanisms of action. 
  • Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis. 
  • Advanced lipoprotein testing does not improve identification of subclinical atherosclerosis in young adults: the Bogalusa Heart Study. 
  • Adverse Cardiovascular Response to Aerobic Exercise Training: Is This a Concern? 
  • Adverse metabolic response to regular exercise: is it a rare or common occurrence? 
  • Age-related macular degeneration and risk of coronary heart disease and stroke: the Cardiovascular Health Study. 
  • Altered lipoprotein subclass distribution and PAF-AH activity in subjects with generalized aggressive periodontitis. 
  • Amelioration of proximal renal tubular dysfunction in type I glycogen storage disease with dietary therapy. 
  • An adverse lipoprotein phenotype-hypertriglyceridaemic hyperapolipoprotein B-and the long-term risk of type 2 diabetes: a prospective, longitudinal, observational cohort study. 
  • Analytical performance and clinical utility of a direct LDL-cholesterol assay in a hyperlipidemic pediatric population. 
  • ApoB-48 and apoB-100 differentially influence the expression of type-III hyperlipoproteinemia in APOE*2 mice. 
  • ApoB. 
  • Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: systematic review and meta-analysis of 14,015 stroke cases and pooled analysis of primary biomarker data from up to 60,883 individuals. 
  • Apolipoprotein E-deficient mice created by systemic administration of antisense oligodeoxynucleotides: a new model for lipoprotein metabolism studies. 
  • Assessing the accuracy of a point-of-care analyzer for hyperlipidaemia in western Kenya. 
  • Assessment of intrahepatic triglyceride content using magnetic resonance spectroscopy. 
  • Association Between Magnetic Resonance Imaging-Proton Density Fat Fraction and Liver Histology Features in Patients With Nonalcoholic Fatty Liver Disease or Nonalcoholic Steatohepatitis. 
  • Association Between Triglycerides and Residual Cardiovascular Risk in Patients With Type 2 Diabetes Mellitus and Established Cardiovascular Disease (From the Bypass Angioplasty Revascularization Investigation 2 Diabetes [BARI 2D] Trial). 
  • Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels. 
  • Association of HIV serostatus and metabolic syndrome with neurobehavioral disturbances. 
  • Association of levels of lipoprotein Lp(a), plasma lipids, and other lipoproteins with coronary artery disease documented by angiography. 
  • Association of lipid profile biomarkers with breast cancer by molecular subtype: analysis of the MEND study. 
  • Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks. 
  • Association study of genetic polymorphisms of SLC2A10 gene and type 2 diabetes in the Taiwanese population. 
  • Associations between APOE variants and metabolic traits and the impact of psychological stress. 
  • Associations between cardiovascular risk factors and early age-related macular degeneration in a rural Chinese adult population. 
  • Associations of ABCB1 and IL-10 genetic polymorphisms with sirolimus-induced dyslipidemia in renal transplant recipients. 
  • Associations of gestational cardiovascular health with pregnancy outcomes: the Hyperglycemia and Adverse Pregnancy Outcome study. 
  • Atherogenic dyslipidemia and residual cardiovascular risk in statin-treated patients. 
  • Basal laminar deposit formation in APO B100 transgenic mice: complex interactions between dietary fat, blue light, and vitamin E. 
  • Baseline blood pressure, low- and high-density lipoproteins, and triglycerides and the risk of vascular events in the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial. 
  • Bed rest worsens impairments in fat and glucose metabolism in older, overweight adults. 
  • Behavioral health mediators of the link between posttraumatic stress disorder and dyslipidemia. 
  • Beneficial effects of pinacidil on blood lipids: comparisons with prazosin and placebo in patients with hypertension. Pinacidil-Prazosin and Pinacidil-Placebo Research Groups, Lilly Research Laboratories. 
  • Beverage Consumption and Longitudinal Changes in Lipoprotein Concentrations and Incident Dyslipidemia in US Adults: The Framingham Heart Study. 
  • Bezafibrate induces autophagy and improves hepatic lipid metabolism in glycogen storage disease type Ia. 
  • Biochemical mechanism of lipid-induced impairment of glucose-stimulated insulin secretion and reversal with a malate analogue. 
  • Biological, clinical and population relevance of 95 loci for blood lipids. 
  • Branched-chain α-keto acids and glutamate/glutamine: Biomarkers of insulin resistance in childhood obesity. 
  • Bupropion SR vs. placebo for weight loss in obese patients with depressive symptoms. 
  • C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis. 
  • CCAAT/enhancer-binding protein beta deletion reduces adiposity, hepatic steatosis, and diabetes in Lepr(db/db) mice. 
  • Calibration of methylene-referenced lipid-dissolved xenon frequency for absolute MR temperature measurements. 
  • Cardio-metabolic risk factors and prehypertension in persons without diabetes, hypertension, and cardiovascular disease. 
  • Cardiometabolic Correlates of Physical Activity and Sedentary Patterns in U.S. Youth. 
  • Cardiometabolic Risks and Severity of Obesity in Children and Young Adults. 
  • Cardiovascular risk factor profiles in familial hypercholesterolemia patients with and without genetic mutation compared to a nationally representative sample of adults in a high-risk European country. 
  • Causal associations of blood lipids with risk of ischemic stroke and intracerebral hemorrhage in Chinese adults. 
  • Causal effects of cardiovascular risk factors on onset of major age-related diseases: A time-to-event Mendelian randomization study. 
  • Changes in lipid values and lipoprotein patterns of serum samples contaminated with bacteria. 
  • Changes in plasma lipid and lipoprotein levels in men and women after a program of moderate exercise. 
  • Changes in serum lipids in patients with condylomata acuminata treated with interferon alfa-n1 (Wellferon). 
  • Characterization of Adipogenic Chemicals in Three Different Cell Culture Systems: Implications for Reproducibility Based on Cell Source and Handling. 
  • Chemical shift imaging of atherosclerosis at 7.0 Tesla. 
  • Cholesterol and cognitive performance among community volunteers from the Czech Republic. 
  • Cholesterol curves to identify population norms by age and sex in healthy weight children. 
  • Cholesterol levels and in-hospital mortality in patients with acute decompensated heart failure. 
  • Chronic family stress moderates the association between a TOMM40 variant and triglyceride levels in two independent Caucasian samples. 
  • Chylomicron formation and secretion is required for lipid-stimulated release of incretins GLP-1 and GIP. 
  • Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. 
  • Common variants associated with plasma triglycerides and risk for coronary artery disease. 
  • Comparison of Recommended Eligibility for Primary Prevention Statin Therapy Based on the US Preventive Services Task Force Recommendations vs the ACC/AHA Guidelines. 
  • Comparison of low- and high-carbohydrate diets for type 2 diabetes management: a randomized trial. 
  • Contraction of insulin-resistant muscle normalizes insulin action in association with increased mitochondrial activity and fatty acid catabolism. 
  • Conversion to atorvastatin in patients intolerant or refractory to simvastatin therapy: the CAPISH study. 
  • Cord blood lipids in infants born to HIV-1-infected women treated with combination antiretroviral therapy. 
  • Correction of diet-induced hyperglycemia, hyperinsulinemia, and skeletal muscle insulin resistance by moderate hyperleptinemia. 
  • Correction: Mouse Models of Diet-Induced Nonalcoholic Steatohepatitis Reproduce the Heterogeneity of the Human Disease. 
  • Correlates of systolic and diastolic blood pressure in men 40 to 59 years of age sampled from United States of America and Union of Soviet Socialist Republics Lipid Research Clinics populations. 
  • DIACYLGLYCEROL ACYLTRANSFERASE1 Contributes to Freezing Tolerance. 
  • Deletion of p47phox attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-deficient mice. 
  • Delivery of glucose-6-phosphatase in a canine model for glycogen storage disease, type Ia, with adeno-associated virus (AAV) vectors. 
  • Detection of dyslipoproteinemia with the use of plasma total cholesterol and triglyceride as screening tests. The Lipid Research Clinics Program Prevalence Study. 
  • Determination of high density lipoprotein-cholesterol in stored human plasma. 
  • Diet and exercise interventions reduce intrahepatic fat content and improve insulin sensitivity in obese older adults. 
  • Dietary branched-chain amino acid restriction alters fuel selection and reduces triglyceride stores in hearts of Zucker fatty rats. 
  • Dietary fructose reduces circulating insulin and leptin, attenuates postprandial suppression of ghrelin, and increases triglycerides in women. 
  • Dietary lipids in glycogen storage disease type III: A systematic literature study, case studies, and future recommendations. 
  • Dietary patterns and the metabolic syndrome in obese and non-obese Framingham women. 
  • Differential association of serum lipids with diabetic retinopathy and diabetic macular edema. 
  • Differential changes in plasma high-density lipoprotein-cholesterol levels in obese men and women during weight reduction 
  • Differential metabolic effects of adenovirus-mediated glucokinase and hexokinase I overexpression in rat primary hepatocytes. 
  • Direct antidiabetic effect of leptin through triglyceride depletion of tissues. 
  • Discordant risk: overweight and cardiometabolic risk in Chinese adults. 
  • Discovery and refinement of loci associated with lipid levels. 
  • Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver. 
  • Distinct patterns of fat metabolism in skeletal muscle of normal-weight, overweight, and obese humans. 
  • Distinctive clinical and genetic features of lean vs overweight fatty liver disease using the UK Biobank. 
  • Domain 3 of hepatitis C virus core protein is sufficient for intracellular lipid accumulation. 
  • Dyslipidaemia and microvascular disease in the retina. 
  • Effect of actinomycin D on serum betalipoproteins of partially hepatectomized dogs. I. Proteins, lipids, triglycerides and cholesterol. 
  • Effect of apolipoproteins on the induction of hepatic steatosis in rats. 
  • Effect of apoproteins on hepatic uptake of triglyceride emulsions in the rat. 
  • Effect of whole body gamma irradiation on fatty acid composition of liver lipids of female rats and radioprotection by cystamine. 
  • Effects of PREMIER lifestyle modifications on participants with and without the metabolic syndrome. 
  • Effects of Sacubitril/Valsartan on Serum Lipids in Heart Failure With Preserved Ejection Fraction. 
  • Effects of Tirzepatide, a Dual GIP and GLP-1 RA, on Lipid and Metabolite Profiles in Subjects With Type 2 Diabetes. 
  • Effects of aerobic training with and without weight loss on insulin sensitivity and lipids. 
  • Effects of estrogen/progestin agents on plasma retinoids and chylomicron remnant metabolism. 
  • Effects of exercise on lipoprotein particles in women with polycystic ovary syndrome. 
  • Effects of exercise on the Type A (coronary prone) behavior pattern. 
  • Effects of exercise training on cardiovascular function and plasma lipid, lipoprotein, and apolipoprotein concentrations in premenopausal and postmenopausal women. 
  • Effects of exercise training on ventricular function in patients with recent myocardial infarction. 
  • Effects of ezetimibe, simvastatin and ezetimibe/simvastatin on correlations between apolipoprotein B, LDL cholesterol and non-HDL cholesterol in patients with primary hypercholesterolemia. 
  • Effects of fasting, refeeding, and intraluminal triglyceride on proglucagon expression in jejunum and ileum. 
  • Effects of heparin and cardiac catheterization on serum lipoprotein and triglyceride levels. 
  • Effects of low-carbohydrate diets versus low-fat diets on metabolic risk factors: a meta-analysis of randomized controlled clinical trials. 
  • Effects of low-carbohydrate vs low-fat diets on weight loss and cardiovascular risk factors: a meta-analysis of randomized controlled trials. 
  • Effects of the amount and intensity of exercise on plasma lipoproteins. 
  • Effects on blood lipids of a blood pressure-lowering diet: the Dietary Approaches to Stop Hypertension (DASH) Trial. 
  • Efficacy and Safety of Alternate-Day Versus Daily Dosing of Statins: a Systematic Review and Meta-Analysis. 
  • Efficacy and safety of acarbose in metformin-treated patients with type 2 diabetes. 
  • Efficacy of provitamin A carotenoids in reversing vitamin A deficiency induced lesions in brain lipids of chicks. 
  • Elevated hepatocyte levels of the Forkhead box A2 (HNF-3beta) transcription factor cause postnatal steatosis and mitochondrial damage. 
  • Elevated resistin levels induce central leptin resistance and increased atherosclerotic progression in mice. 
  • Enhanced GLUT4-Dependent Glucose Transport Relieves Nutrient Stress in Obese Mice Through Changes in Lipid and Amino Acid Metabolism. 
  • Exenatide Protects Against Glucose- and Lipid-Induced Endothelial Dysfunction: Evidence for Direct Vasodilation Effect of GLP-1 Receptor Agonists in Humans. 
  • Exercise effects on lipids in persons with varying dietary patterns-does diet matter if they exercise? Responses in Studies of a Targeted Risk Reduction Intervention through Defined Exercise I. 
  • Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction. 
  • Expanded Clinical Evaluation of Lovastatin (EXCEL) study results. Effect of patient characteristics on lovastatin-induced changes in plasma concentrations of lipids and lipoproteins. 
  • Extended-release niacin for modifying the lipoprotein profile. 
  • Extended-release niacin therapy and risk of ischemic stroke in patients with cardiovascular disease: the Atherothrombosis Intervention in Metabolic Syndrome with low HDL/High Triglycerides: Impact on Global Health Outcome (AIM-HIGH) trial. 
  • Extended-release niacin vs gemfibrozil for the treatment of low levels of high-density lipoprotein cholesterol. Niaspan-Gemfibrozil Study Group. 
  • Extreme elevations of low-density lipoprotein cholesterol with very low carbohydrate, high fat diets. 
  • Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes. 
  • Fasting might not be necessary before lipid screening: a nationally representative cross-sectional study. 
  • Fat distribution and glucose metabolism in older, obese men and women. 
  • Fatty acid elongase-5 (Elovl5) regulates hepatic triglyceride catabolism in obese C57BL/6J mice. 
  • Female steroid hormones and lipoprotein synthesis in the cockerel: effects of progesterone and nafoxidine on the estrogenic stimulation of very low density lipoproteins (VLDL) synthesis. 
  • Fenofibrate rapidly decreases hepatic lipid and glycogen storage in neonatal mice with glycogen storage disease type Ia. 
  • Flicker light-induced retinal vasodilation in diabetes and diabetic retinopathy. 
  • Frequency of low serum high-density lipoprotein cholesterol levels in hospitalized patients with "desirable" total cholesterol levels. 
  • Fructose and glucose can regulate mammalian target of rapamycin complex 1 and lipogenic gene expression via distinct pathways. 
  • GLP-1 reduces intestinal lymph flow, triglyceride absorption, and apolipoprotein production in rats. 
  • Gain-of-function lipoprotein lipase variant rs13702 modulates lipid traits through disruption of a microRNA-410 seed site. 
  • Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations. 
  • Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels. 
  • Genetically determined height and coronary artery disease. 
  • Glucose down-regulates the expression of the peroxisome proliferator-activated receptor-alpha gene in the pancreatic beta -cell. 
  • Glycated hemoglobin and the risk of kidney disease and retinopathy in adults with and without diabetes. 
  • Glycerol-3-phosphate acyltransferase (GPAT)-1, but not GPAT4, incorporates newly synthesized fatty acids into triacylglycerol and diminishes fatty acid oxidation. 
  • HPLC measurement, blood distribution, and pharmacokinetics of oral clotrimazole, potentially useful antisickling agent. 
  • Hepatic Lipid Catabolism via PPARα-Lysosomal Crosstalk. 
  • Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance. 
  • Hepatic insulin signaling is required for obesity-dependent expression of SREBP-1c mRNA but not for feeding-dependent expression. 
  • Hepatic mitochondrial dysfunction is a feature of Glycogen Storage Disease Type Ia (GSDIa). 
  • Hepatic overexpression of glycerol-sn-3-phosphate acyltransferase 1 in rats causes insulin resistance. 
  • Hepatic triglyceride synthesis and nonalcoholic fatty liver disease. 
  • Hepatotoxic effects of CCl4 on English sole (Parophrys vetulus): possible indicators of liver dysfunction. 
  • Heterogeneity of healthy aging: comparing long-lived families across five healthy aging phenotypes of blood pressure, memory, pulmonary function, grip strength, and metabolism. 
  • High normal plasma triglycerides are associated with preserved cognitive function in Chinese oldest-old. 
  • High-density lipoprotein subfractions. 
  • Higher high-density lipoprotein cholesterol in African-American women with polycystic ovary syndrome compared with Caucasian counterparts. 
  • Hypercholesterolemia in rats with chronic renal insufficiency not aggravated by recombinant human growth hormone. 
  • Hypertriglyceridemia in Dahl rats: effect of sodium intake and gender. 
  • Impact of antipsychotic treatment on nonfasting triglycerides in the CATIE Schizophrenia Trial phase 1. 
  • Impact of gene variants on sex-specific regulation of human Scavenger receptor class B type 1 (SR-BI) expression in liver and association with lipid levels in a population-based study. 
  • Impact of psychological stress on the associations between apolipoprotein E variants and metabolic traits: findings in an American sample of caregivers and controls. 
  • In vivo NMR detection of diet-induced changes in adipose tissue composition. 
  • In vivo acylation of triglycerides and phosphoglycerides of liver subcellular fractions with palmitate-1-14C in rats fed vitamin A. 
  • Inactivation of the Glucose-Dependent Insulinotropic Polypeptide Receptor Improves Outcomes following Experimental Myocardial Infarction. 
  • Incorporation of palmitate-1-14C into liver lipids of rats fed millet (Sorghum vulgarie) at different protein levels. 
  • Increased lipid accumulation and insulin resistance in transgenic mice expressing DGAT2 in glycolytic (type II) muscle. 
  • Increases in serum sphingomyelin by 17 beta-estradiol. 
  • Induction of autophagy improves hepatic lipid metabolism in glucose-6-phosphatase deficiency. 
  • Influence of apolipoprotein E on soluble and heparin-immobilized hepatic lipase. 
  • Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis. 
  • Inhibition of de novo ceramide synthesis reverses diet-induced insulin resistance and enhances whole-body oxygen consumption. 
  • Interaction of methylation-related genetic variants with circulating fatty acids on plasma lipids: a meta-analysis of 7 studies and methylation analysis of 3 studies in the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium. 
  • Interaction of vitamin A and cortisol on liver and plasma lipids of rats. 
  • Intestinal Alkaline Phosphatase Attenuates Alcohol-Induced Hepatosteatosis in Mice. 
  • Intestinal alkaline phosphatase prevents metabolic syndrome in mice. 
  • Intramuscular fatty acid metabolism in contracting and non-contracting human skeletal muscle. 
  • Intramuscular triacylglycerol and insulin resistance: guilty as charged or wrongly accused? 
  • Is nuclear magnetic resonance lipoprotein subclass related to diabetic retinopathy? The multi-ethnic study of atherosclerosis (MESA). 
  • Laboratory markers of cardiovascular risk in pediatric SLE: the APPLE baseline cohort. 
  • Leptin directly alters lipid partitioning in skeletal muscle. 
  • Leptin opposes insulin's effects on fatty acid partitioning in muscles isolated from obese ob/ob mice. 
  • Leptin therapy in insulin-deficient type I diabetes. 
  • Lipid Effects of Icosapent Ethyl in Women with Diabetes Mellitus and Persistent High Triglycerides on Statin Treatment: ANCHOR Trial Subanalysis. 
  • Lipid changes associated with antiretroviral therapy: results differ by reporting approach. 
  • Lipid levels in patients hospitalized with coronary artery disease: an analysis of 136,905 hospitalizations in Get With The Guidelines. 
  • Lipids and lactate in human immunodeficiency virus-1 infected pregnancies with or without protease inhibitor-based therapy. 
  • Lipoprotein (a): purification and kinetic analysis. 
  • Lipoprotein response to exercise training and a low-fat diet in older subjects with glucose intolerance. 
  • Lipoprotein-like particles and cholesteryl esters in human Bruch's membrane: initial characterization. 
  • Liver fibrosis during clinical ascertainment of glycogen storage disease type III: a need for improved and systematic monitoring. 
  • Liver transplantation for glycogen storage disease type Ia. 
  • Liver-specific loss of long chain acyl-CoA synthetase-1 decreases triacylglycerol synthesis and beta-oxidation and alters phospholipid fatty acid composition. 
  • Long-term efficacy and safety of mipomersen in patients with familial hypercholesterolaemia: 2-year interim results of an open-label extension. 
  • Lovastatin and coadministered antihypertensive/cardiovascular agents. 
  • Lovastatin increases exercise-induced skeletal muscle injury. 
  • Low glycemic diet for weight loss in hypertriglyceridemic patients attending a lipid clinic. 
  • Low-density lipoprotein 4: a novel predictor of coronary artery disease severity. 
  • Major lipids, apolipoproteins, and risk of vascular disease. 
  • Maternal BMI and Glycemia Impact the Fetal Metabolome. 
  • Maternal Dietary Patterns are Associated with Lower Levels of Cardiometabolic Markers during Pregnancy. 
  • Maternal metabolites during pregnancy are associated with newborn outcomes and hyperinsulinaemia across ancestries. 
  • Mediation of the APOE associations with Alzheimer's and coronary heart diseases through body mass index and lipids. 
  • Metabolic Networks and Metabolites Underlie Associations Between Maternal Glucose During Pregnancy and Newborn Size at Birth. 
  • Metabolic effects and efficacy of a triphasic oral contraceptive (norgestimate/ethinyl estradiol). 
  • Metabolic profiling of muscle contraction in lean compared with obese rodents. 
  • Metabolic remodeling of human skeletal myocytes by cocultured adipocytes depends on the lipolytic state of the system. 
  • Metabolic syndrome and risk of age-related cataract over time: an analysis of interval-censored data using a random-effects model. 
  • Metabolic syndrome components and age-related cataract: the Singapore Malay eye study. 
  • Metabolic syndrome, C-reactive protein, and prognosis in patients with established coronary artery disease. 
  • Metabolomic profiling identifies complex lipid species and amino acid analogues associated with response to weight loss interventions. 
  • Metabolomics reveals broad-scale metabolic perturbations in hyperglycemic mothers during pregnancy. 
  • Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential in liver for the metabolism of excess acyl-CoAs. 
  • Modification of postprandial hyperglycemia with insulin lispro improves glucose control in patients with type 2 diabetes. 
  • Mouse models of diet-induced nonalcoholic steatohepatitis reproduce the heterogeneity of the human disease. 
  • Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity. 
  • Multi-dimensional characterization of prediabetes in the Project Baseline Health Study. 
  • Multi-omic profiles of hepatic metabolism in TPN-fed preterm pigs administered new generation lipid emulsions. 
  • Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. 
  • Multiple genetic variants explain measurable variance in type 2 diabetes-related traits in Pakistanis. 
  • Myocardial Lipin 1 knockout in mice approximates cardiac effects of human LPIN1 mutations. 
  • Myocardial Steatosis Among Antiretroviral Therapy-Treated People With Human Immunodeficiency Virus Participating in the REPRIEVE Trial. 
  • NAFLD is associated with methylation shifts with relevance for the expression of genes involved in lipoprotein particle composition. 
  • Niacin and heart disease prevention: Engraving its tombstone is a mistake. 
  • Night shift work and cardiovascular disease biomarkers in female nurses. 
  • Nonfasting triglycerides and cardiovascular risk. 
  • Nonionic Ethoxylated Surfactants Induce Adipogenesis in 3T3-L1 Cells. 
  • Nuclear estrogen receptor in the avian liver: correlation with biologic response. 
  • Nutrition for the diabetic pregnant woman. 
  • Nutritional supplements for older adults: review and recommendations--Part II. 
  • Osteopontin deficiency ameliorates Alport pathology by preventing tubular metabolic deficits. 
  • PPARγ coactivator-1α contributes to exercise-induced regulation of intramuscular lipid droplet programming in mice and humans. 
  • Parenteral and enteral metabolism of anaplerotic triheptanoin in normal rats. II. Effects on lipolysis, glucose production, and liver acyl-CoA profile. 
  • Pathogenesis of hepatic steatosis in the parenterally fed rat. 
  • Periodontitis and multiple markers of cardiometabolic risk in the fourth decade: A cohort study. 
  • Peripapillary choroidal thickness assessed using automated choroidal segmentation software in an Asian population. 
  • Peripheral artery disease and glaucoma: the singapore malay eye study. 
  • Peroxisome proliferator-activated receptor-alpha regulates fatty acid utilization in primary human skeletal muscle cells. 
  • Perturbation of fuel homeostasis caused by overexpression of the glucose-6-phosphatase catalytic subunit in liver of normal rats. 
  • Phosphatase and tensin homolog (PTEN) regulates hepatic lipogenesis, microsomal triglyceride transfer protein, and the secretion of apolipoprotein B-containing lipoproteins. 
  • Physical activity, television viewing time, and retinal vascular caliber. 
  • Physiological and nutritional regulation of enzymes of triacylglycerol synthesis. 
  • Plasma fibrinogen levels and their correlates in 6457 coronary heart disease patients. The Bezafibrate Infarction Prevention (BIP) Study. 
  • Plasma lipoproteins of free-ranging howling monkeys (Alouatta palliata). 
  • Poor oral health is associated with coronary heart disease and elevated systemic inflammatory and haemostatic factors. 
  • Populations and methods for assessing dyslipoproteinemia and its correlates. The Lipid Research Clinics Program Prevalence Study. 
  • Postprandial triglycerides in response to high fat: role of dietary carbohydrate. 
  • Pparg-P465L mutation worsens hyperglycemia in Ins2-Akita female mice via adipose-specific insulin resistance and storage dysfunction. 
  • Prevalence of cardiovascular risk factors and the serum levels of 25-hydroxyvitamin D in the United States: data from the Third National Health and Nutrition Examination Survey. 
  • Prevalence of lipid abnormalities in Poland. The NATPOL 2011 survey. 
  • Prevalence of the metabolic syndrome in patients with schizophrenia: baseline results from the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) schizophrenia trial and comparison with national estimates from NHANES III. 
  • Prevalences of type 2 diabetes, the insulin resistance syndrome, and coronary heart disease in an elderly, biethnic population. 
  • Pro- and antiatherogenic effects of a dominant-negative P465L mutation of peroxisome proliferator-activated receptor-γ in apolipoprotein E-Null mice. 
  • Prognostic significance of serum total cholesterol and triglyceride levels in patients hospitalized for heart failure with reduced ejection fraction (from the EVEREST Trial). 
  • Protection from death in endotoxin shock: does fish oil need a LIF? 
  • Quantitative and Qualitative Role of Antagonistic Heterogeneity in Genetics of Blood Lipids. 
  • Racial differences in the interaction between family history and risk factors associated with diabetes in the National Health and Nutritional Examination Survey, 1999-2004. 
  • Radioprotection of liver lipids of whole-body gamma-irradiated female rats by cystamine. 
  • Rapid and weight-independent improvement of glucose tolerance induced by a peptide designed to elicit apoptosis in adipose tissue endothelium. 
  • Rationale and design of a secondary prevention trial of increasing serum high-density lipoprotein cholesterol and reducing triglycerides in patients with clinically manifest atherosclerotic heart disease (the Bezafibrate Infarction Prevention Trial). 
  • Re-patterning of skeletal muscle energy metabolism by fat storage-inducing transmembrane protein 2. 
  • Reduction of atherogenic risk factors by short-term weight reduction. Evidence of the efficacy of National Cholesterol Education Program guidelines for the obese. 
  • Refocusing the AIM on HDL in the metabolic syndrome. 
  • Relation of fish oil supplementation to markers of atherothrombotic risk in patients with cardiovascular disease not receiving lipid-lowering therapy. 
  • Relations of GlycA and lipoprotein particle subspecies with cardiovascular events and mortality: A post hoc analysis of the AIM-HIGH trial. 
  • Relations of trait depression and anxiety to low lipid and lipoprotein concentrations in healthy young adult women. 
  • Relationship of lipoproteins to cardiovascular events: the AIM-HIGH Trial (Atherothrombosis Intervention in Metabolic Syndrome With Low HDL/High Triglycerides and Impact on Global Health Outcomes). 
  • Relative and cumulative effects of lipid and blood pressure control in the Stroke Prevention by Aggressive Reduction in Cholesterol Levels trial. 
  • Relative effects of statin therapy on stroke and cardiovascular events in men and women: secondary analysis of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) Study. 
  • Renal Disease Risk Factors Among Risk Groups Comprised of African American Women With Type 2 Diabetes: A Secondary Analysis. 
  • Reproducibility of adipogenic responses to metabolism disrupting chemicals in the 3T3-L1 pre-adipocyte model system: An interlaboratory study. 
  • Response to low-carbohydrate diets and cardiovascular risk factors by Santos et al. 
  • Retinol and adrenal lipids of rats. 
  • Retinol feeding and low and high density lipoproteins of plasma of rats. 
  • Reversing adipocyte differentiation: implications for treatment of obesity. 
  • Risk of stroke and cardiovascular events after ischemic stroke or transient ischemic attack in patients with type 2 diabetes or metabolic syndrome: secondary analysis of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial. 
  • Role of homocysteine & MTHFR C677T gene polymorphism as risk factors for coronary artery disease in young Indians. 
  • SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. 
  • Separation & estimation of human serum lipids by silicic acid column chromatography. 
  • Serum Cholesterol Levels within the High Normal Range Are Associated with Better Cognitive Performance among Chinese Elderly. 
  • Serum apolipoprotein AI and B are stronger biomarkers of diabetic retinopathy than traditional lipids. 
  • Serum lipid profile and risk of prostate cancer recurrence: Results from the SEARCH database. 
  • Serum triglyceride elevation following high-dose vitamin A treatment for pityriasis rubra pilaris. 
  • Serum triglycerides in Alzheimer disease: Relation to neuroimaging and CSF biomarkers. 
  • Sex differences in biomarkers associated with insulin resistance in obese adolescents: metabolomic profiling and principal components analysis. 
  • Short-term effects of dietary fatty acids on muscle lipid composition and serum acylcarnitine profile in human subjects. 
  • Sinorhizobium meliloti phospholipase C required for lipid remodeling during phosphorus limitation. 
  • Skeletal muscle-specific Cre recombinase expression, controlled by the human α-skeletal actin promoter, improves glucose tolerance in mice fed a high-fat diet. 
  • Studies on mode of action of vitamin A. 
  • Studies on the cellular toxicity of polychlorinated biphenyls (PCBs). I. Effect of PCBs on microsomal enzymes and on synthesis and turnover of microsomal and cytoplasmic lipids of rat liver- a morphological and biochemical study. 
  • Sugar-Sweetened Beverage Consumption May Modify Associations Between Genetic Variants in the CHREBP (Carbohydrate Responsive Element Binding Protein) Locus and HDL-C (High-Density Lipoprotein Cholesterol) and Triglyceride Concentrations. 
  • Systematic review and meta-analysis of clinical trials of the effects of low carbohydrate diets on cardiovascular risk factors. 
  • Targeted replacement of the mouse apolipoprotein E gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis. 
  • Testing for causality between systematically identified risk factors and glioma: a Mendelian randomization study. 
  • The Association Between Lipoproteins, Disability, and Physical Function Among Older Costa Rican Adults. 
  • The Clinical Antipsychotic Trials Of Intervention Effectiveness (CATIE) Schizophrenia Trial: clinical comparison of subgroups with and without the metabolic syndrome. 
  • The Dose-Response Relationship Between Physical Activity and Cardiometabolic Health in Young Adults. 
  • The Emerging Risk Factors Collaboration: analysis of individual data on lipid, inflammatory and other markers in over 1.1 million participants in 104 prospective studies of cardiovascular diseases. 
  • The Gut Microbiota Modulates Energy Metabolism in the Hibernating Brown Bear Ursus arctos. 
  • The absorption of oleic acid from emulsion and micellar solution. 
  • The absorption of tristearin and stearic acid and tripalmitin and palmitic acid. Studies on the rate-limiting steps in rats. 
  • The association between triglycerides and incident cardiovascular disease: What is "optimal"? 
  • The association between weight change and symptom reduction in the CATIE schizophrenia trial. 
  • The effect of choline supplementation on hepatic steatosis in the parenterally fed rat. 
  • The emerging role of novel antihyperglycemic agents in the treatment of heart failure and diabetes: A focus on cardiorenal outcomes. 
  • The genetic response to short-term interventions affecting cardiovascular function: rationale and design of the Heredity and Phenotype Intervention (HAPI) Heart Study. 
  • The high-production volume fungicide pyraclostrobin induces triglyceride accumulation associated with mitochondrial dysfunction, and promotes adipocyte differentiation independent of PPARγ activation, in 3T3-L1 cells. 
  • The impact of race on metabolic disease risk factors in women with and without posttraumatic stress disorder. 
  • The retina in type 5 hyperlipoproteinemia. 
  • The role of aging, high fat diet and blue light exposure in an experimental mouse model for basal laminar deposit formation. 
  • The structure of helical lipoprotein lipase reveals an unexpected twist in lipase storage. 
  • The use of lipid-lowering drugs in children. 
  • Therapy and clinical trials. 
  • Thiazolidinediones, peripheral oedema and congestive heart failure: what is the evidence? 
  • Thyroid Hormone Decreases Hepatic Steatosis, Inflammation, and Fibrosis in a Dietary Mouse Model of Nonalcoholic Steatohepatitis. 
  • Thyroid receptor antagonism as a contributory mechanism for adipogenesis induced by environmental mixtures in 3T3-L1 cells. 
  • Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained. 
  • Transport of free fatty acid and triglyceride in anhepatic rats. 
  • Triglyceride Induced Metabolic Inflammation: Potential Connection of Insulin Resistance and Recurrent Pregnancy Loss. 
  • Triglyceride-lowering therapies reduce cardiovascular disease event risk in subjects with hypertriglyceridemia. 
  • Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies. 
  • Triglycerides Paradox Among the Oldest Old: "The Lower the Better?". 
  • Triglycerides: Emerging Targets in Diabetes Care? Review of Moderate Hypertriglyceridemia in Diabetes. 
  • Triheptanoin versus trioctanoin for long-chain fatty acid oxidation disorders: a double blinded, randomized controlled trial. 
  • Turnover of pancreas phospholipids in rats fed inadequate dietary protein. 
  • Type III hyperlipoproteinemia and spontaneous atherosclerosis in mice resulting from gene replacement of mouse Apoe with human Apoe*2. 
  • Universal Cholesterol Screening in Childhood: A Systematic Review. 
  • Upake of plasma lipids by extrahepatic tissues of vitamin A fed rats. 
  • Use of ketoconazole to probe the pathogenetic importance of 1,25-dihydroxyvitamin D in absorptive hypercalciuria. 
  • Usefulness of Icosapent Ethyl (Eicosapentaenoic Acid Ethyl Ester) in Women to Lower Triglyceride Levels (Results from the MARINE and ANCHOR Trials). 
  • Using the lymph fistula rat model to study the potentiation of GIP secretion by the ingestion of fat and glucose. 
  • Variability of renal length in type I glycogen storage disease. 
  • Weight-based teasing in youth: Associations with metabolic and inflammatory markers. 
  • Whole Blood DNA Methylation Signatures of Diet Are Associated With Cardiovascular Disease Risk Factors and All-Cause Mortality. 
  • [Association between serum albumin and cognitive performance in elderly Chinese]. 
  • [Middle chain triglycerides]. 
• 

  Keywords of People

  • Charles, Hal Cecil, Adjunct Associate Professor in the Department of Radiology, Radiology
  • Choi, Steven Sok, Associate Professor of Medicine, Medicine, Gastroenterology
  • Freemark, Michael Scott, Robert C. Atkins, M.D. and Veronica Atkins Distinguished Professor of Pediatrics, in the School of Medicine, Pediatrics, Endocrinology
  • Hirschey, Matthew, Associate Professor of Medicine, Cell Biology
  • O'Connor, Christopher Michael, Richard Sean Stack, M.D. Distinguished Professor, Medicine, Clinical Pharmacology
  • Preminger, Glenn Michael, James F. Glenn, M.D. Distinguished Professor of Urology, Surgery, Urology
  • Schanberg, Laura Eve, Professor of Pediatrics, Pediatrics, Rheumatology
  • Stinnett, Sandra Sue, Associate Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics
  • Yancy Jr., William Samuel, Professor of Medicine, Medicine, General Internal Medicine