Trisomy

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  Subject Areas on Research

  • A de novo direct duplication of 16q22.1 --> q23.1 in a boy with midface hypoplasia and mental retardation. 
  • Abnormal amniotic fetal antigen 2 concentrations in trisomy 18 and trisomy 21. 
  • Abnormal production of interleukin-1 by microglia from trisomy 16 mice. 
  • Composite lymphoma of follicular B-cell and peripheral T-cell types with distinct zone distribution in a 75-year-old male patient: a case study. 
  • Concurrent acute myeloid leukemia with inv(16)(p13.1q22) and chronic lymphocytic leukemia: molecular evidence of two separate diseases. 
  • Constellation of congenital abnormalities in an infant: a new syndrome or tissue-specific mosaicism for trisomy 18? 
  • Cytogenetics and mechanisms of spontaneous abortions: increased apoptosis and decreased cell proliferation in chromosomally abnormal villi. 
  • Detection of trisomy 12 by fluorescence in situ hybridization on archival cytopathologic material in chronic lymphocytic leukemia/small lymphocytic lymphoma. 
  • Down syndrome childhood acute lymphoblastic leukemia has a unique spectrum of sentinel cytogenetic lesions that influences treatment outcome: a report from the Children's Oncology Group. 
  • Enhanced production of superoxide anion by microglia from trisomy 16 mice. 
  • Evidence for a striking increase in acetylcholinesterase activity in cultured human fibroblasts which are trisomic for chromosome two. 
  • Fetal choroid plexus lesions. Relationship of antenatal sonographic appearance to clinical outcome. 
  • Increased expression of NR2A subunit does not alter NMDA-evoked responses in cultured fetal trisomy 16 mouse hippocampal neurons. 
  • Interphase fluorescence in situ hybridization for trisomy 12 on archival ovarian sex cord-stromal tumors. 
  • Isolated trisomy of chromosomes 8, 11, 13 and 21 is an adverse prognostic factor in adults with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B 8461. 
  • Malignant giant cell tumor of synovium (malignant pigmented villonodular synovitis). 
  • Management Considerations for Ongoing Pregnancies Complicated by Trisomy 13 and 18. 
  • Microphthalmia, Dermal Aplasia, and Sclerocornea Syndrome: Endoscopic Cyclophotocoagulation in the Management of Congenital Glaucoma. 
  • Mortality and morbidity of VLBW infants with trisomy 13 or trisomy 18. 
  • Mosaic trisomy 9 hematopoietic chimera. 
  • Perinatal findings of partial trisomy 13q (13q14.1-->qter) resulting from paternal pericentric inversion of chromosome 13. 
  • Prenatal diagnosis and genetic analysis of double trisomy 48,XXX,+18. 
  • Prenatal diagnosis of complete sole trisomy 1q. 
  • Prenatal diagnosis of mosaic trisomy 13: a case report. 
  • Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461). 
  • Prolonged pancytopenia in a gene therapy patient with ADA-deficient SCID and trisomy 8 mosaicism: a case report. 
  • Redox regulation of neuronal migration in a Down Syndrome model. 
  • Simultaneous presence of major secondary chromosomal abnormalities in blast crisis of chronic myeloid leukemia. 
  • Somatic activation of AKT3 causes hemispheric developmental brain malformations. 
  • Transfusion medicine illustrated: Mosaic Trisomy 9 in an infant with mixed-field ABO blood grouping. 
  • Trisomy 15 associated with nonimmune hydrops. 
  • Trisomy 8 mosaicism: selective growth advantage of normal cells vs. growth disadvantage of trisomy 8 cells. 
  • Trisomy of rat chromosome 1 associated with mesothelial cell transformation. 
  • Variegated aneuploidy in two siblings: phenotype, genotype, CENP-E analysis, and literature review.